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Efficacy of Sporicidal Wipes - Cardiff University

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FACTORS AFFECTING SPORICIDAL ACTIVITY!<br />

FACTORS! IMPORTANCE FOR EFFICACY! PREDICTABILITY!<br />

Concentration! +++" Concentration exponent (η) "<br />

Type <strong>of</strong> surface!<br />

!<br />

++" Roughness"<br />

Hydrophobicity "<br />

Charge"<br />

Porosity"<br />

Organic load! +++" Chemical nature <strong>of</strong> active"<br />

Soiling (blood, faeces, etc.) "<br />

Temperature! + " Q 10 "<br />

pH! ++ " Chemical nature <strong>of</strong> active"<br />

Contact time! +++" Continuous release (reservoir)"<br />

Relative humidity! ++" Gaseous biocides"<br />

Formulation! ++" Depend on excipients"<br />

Infection Prevention Society, <strong>Cardiff</strong> 2011!

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