Misoprostol: An emerging technology for women's health

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Misoprostol An emerging technology for women’s health Report of a seminar 7–8 May 2001 Population Council New York, New York Caitlin S. Shannon Beverly Winikoff Editors
The Population Council is an international, nonprofit, nongovernmental organization that seeks to improve the well-being and reproductive health of current and future generations around the world and to help achieve a humane, equitable, and sustainable balance between people and resources. The Council conducts biomedical, social science, and public health research and helps build research capacities in developing countries. Established in 1952, the Council is governed by an international board of trustees. Its New York headquarters supports a global network of regional and country offices. Population Council One Dag Hammarskjold Plaza New York, NY 10017 USA 212/339-0500; fax: 212/755-6052 e-mail: pubinfo@popcouncil.org www.popcouncil.org © 2004 by The Population Council, Inc. Any part of this publication may be photocopied without permission from the authors or publisher, provided that publication credit is given and that copies are distributed free. Any commercial reproduction requires prior written permission from the Population Council.
Page 1: M isoprostol An emerging technology
Page 5 and 6: iv PREFACE Pharmaceutical companies
Page 7 and 8: vi Misoprostol: An emerging technol
Page 9 and 10: 2 BACKGROUND Misoprostol’s Import
Page 11 and 12: 4 BOX 4 Overview of misoprostol Wha
Page 13 and 14: 6 TABLE 1 Misoprostol alone for fir
Page 15 and 16: 8 TABLE 5 Dose-finding studies of m
Page 17 and 18: 10 FIGURE 2 Cumulative abortion rat
Page 19 and 20: 12 3 Creinin, M.D. and E. Vittingho
Page 21 and 22: 14 TABLE 11 Complications following
Page 23 and 24: 16 References 1 Cunningham, G. (ed)
Page 25 and 26: 18 Indeed, while the extensive publ
Page 27 and 28: 20 TABLE 15 Six randomized controll
Page 29 and 30: 22 TABLE 18 Comparison of safety of
Page 31 and 32: 24 Use of Misoprostol During the Th
Page 33 and 34: 26 In summary, use of 600 µg oral
Page 35 and 36: 28 3 el-Refaey, H., P. O’Brien, W
Page 37 and 38: 30 TABLE 22 Benefits of cervical pr
Page 39 and 40: 32 The use of misoprostol in postme
Page 41 and 42: 34 CURRENT MEDICAL PRACTICE In most
Page 43 and 44: 36 TABLE 29 Comparison of most comm
Page 45 and 46: 38 in Latin America, one country in
Page 47 and 48: 40 PRIORITIES FOR RESEARCH AND POLI
Page 49 and 50: 42 THE FUTURE OF MISOPROSTOL FOR WO
Page 51 and 52: 44 8 May 2001 Misoprostol: An Impor
Page 53 and 54:
46 Danielle Hassoun, M.D. Hôpital
Page 55 and 56:
48 APPENDIX C: BIBLIOGRAPHY OF PUBL
Page 57 and 58:
50 ———. 2001. “Misoprostol
Page 59 and 60:
52 Tsai, E.M., C.H. Yang, and J.N.
Page 61 and 62:
54 Benchimol, M., J. Gondry, J.E. M
Page 63 and 64:
56 Mundle, W.R. and D.C Young. 1996
Page 65 and 66:
58 Alfirevic, Z., G. Howarth, and A
Page 67 and 68:
60 Li, L., W. Gao, and S. Chen. 199
Page 69 and 70:
62 Shojai, R., L. Piechon, C. d’E
Page 71 and 72:
64 Poma, P.A. 1999. “Cervical rip
Page 73:
66 Shepard, T.H. 1995. “Mobius sy
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