Psych. Eileen Wollburg

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Psychophysiological Effects of Breathing Training in Panic Disorder and Episodic Anxiety ACKNOWLEDGEMENTS I am deeply grateful to my supervisor Dr. Walton T. Roth, MD, for making this experience possible for me and sharing his expertise throughout the entire time. I would also like to thank Prof. Burkhard Brocke, my supervisor at the Technical University of Dresden, for supporting my intention to write my master’s thesis at Stanford University and continue on to my dissertation. All this work would have not been accomplished without the help of many people. Most of all, my co-workers Joo-Young Song, Pearl Chang, and Jen Sauvé with whom I managed many struggles and joys of conducting a research study. They were extremely helpful in all stages of the project. Great thanks to our student therapists Lindsey Duca, Erin Joyce, Themis Yiaslas, Elizabeth Looney, and Julia Hoffman from the Pacific Graduate School of Psychology. Many thanks to all our international students, especially Paola Cojuangco and Julia Wölffel, who helped to a great extent with data preparation, as well as Franziska Bertram, Julia Burau, Ines Behring, Franziska Schreiber, and our volunteer Jane Hsiao. I cannot express how much I owe to my clinical supervisor Dr. Sunyoung Kim for her encouragement and support in countless ways. My time at Stanford University and the Palo Alto Veterans Hospital would have not been the same without her friendship! This research was supported by grants to Dr. Roth as principal investigator from the National Institute of Health (RO1 MH-66953) and the Department of Veterans Affairs (ROT-42825). ii
Psychophysiological Effects of Breathing Training in Panic Disorder and Episodic Anxiety TABLE OF CONTENTS Acknowledgements……………………………………………………………………….ii Table of contents…………………………………………………………………………iii Acronyms………………………………………………………………………………….v List of Tables and Figures……………………………………………………………….vii Summary………………………………………………………………………….……..viii Zusammenfassung……………………………………………………………..…………..x Introduction…………………………………………………………………………..……1 Respiratory Abnormalities in Panic Disorder...............................................................1 Baseline Differences.............................................................................................1 Voluntary Hyperventilation..................................................................................3 Voluntary Hypoventilation....................................................................................6 Physiological Theories of Panic Disorder...................................................................11 Treatment of Breathing Abnormalities........................................................................14 Respiratory Abnormalities in other Anxiety Patients..................................................16 Method……………………………………………………………………………...……19 Inclusion Criteria.........................................................................................................19 Participant Characteristics..........................................................................................20 Procedure.....................................................................................................................23 Treatment.....................................................................................................................23 Psychological assessment............................................................................................25 Diagnostic Interviews.........................................................................................25 Questionnaires....................................................................................................25 iii
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Psych. Eileen Wollburg

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