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Syphilis Testing in Northern California Kaiser

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Treponemal<br />

Results<br />

negative (nonreactive)<br />

negative (nonreactive)<br />

positive<br />

(reactive)<br />

positive<br />

(reactive)<br />

positive<br />

(reactive)<br />

RPR Q TPPA Report/Interpretation for all except<br />

neonates or <strong>in</strong>fants<br />

not<br />

performe<br />

d<br />

not<br />

performed<br />

reactive nonreactive<br />

nonreactive<br />

nonreactive<br />

No serological evidence of <strong>in</strong>fection with T.<br />

pallidum (<strong>in</strong>cubat<strong>in</strong>g or early primary syphilis<br />

cannot be excluded)<br />

Current <strong>in</strong>fection unlikely, probability of<br />

biological false positive secondary to other<br />

medical conditions (febrile diseases,<br />

immunization, IVDU, autoimmune diseases, etc.)<br />

reactive Probably past treated <strong>in</strong>fection; additional<br />

test<strong>in</strong>g maybe necessary for cl<strong>in</strong>ical suspicion of<br />

late syphilis or neurosyphilis.<br />

nonreactive<br />

reactive not<br />

performed<br />

Probably false positive Trep Antibody result<br />

Cl<strong>in</strong>ical correlation required<br />

Evidence of current <strong>in</strong>fection (if low positive<br />

RPR with history of treatment, this is serofast<br />

state.)

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