Richard Silver PV
Richard Silver PV
Richard Silver PV
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How should “early” <strong>PV</strong> be diagnosed?<br />
RBC remains preferable.<br />
• Absolute increase in red blood cells<br />
(not Hgb), RBC determined by RCM<br />
using Cr 51.<br />
• JAK2 V617F or Exon 12 mutation always<br />
present n = 292 (The Cornell<br />
experience)<br />
• Virtually always accompanied by other<br />
evidence of myeloproliferation<br />
(confirmatory)
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