Comparison of Candesartan vs Amlodipine Comparison of ...
Comparison of Candesartan vs Amlodipine Comparison of ...
Comparison of Candesartan vs Amlodipine Comparison of ...
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<strong>Candesartan</strong> <strong>vs</strong> <strong>vs</strong> Standard Standard with ACEi<br />
Primary endpoint<br />
MACE<br />
CV death + MI<br />
UAP<br />
HF<br />
Stroke<br />
other CV events<br />
Secondary endpoints<br />
<strong>Candesartan</strong> ACEi HR<br />
P<br />
(n=1024) (n=723) [95%CI] value<br />
264 (25.8%)<br />
57 (5.6%)<br />
151 (14.7%) ( %)<br />
40 (3.9%)<br />
45 (4.4%)<br />
35 (3.4%)<br />
203 (28.1%)<br />
40 (5.5%)<br />
117 (16.2%)<br />
35 (4.8%)<br />
38 (5.3%)<br />
27 (3.7%)<br />
0.90 [0.75-1.08]<br />
1.01 [0.67-1.51]<br />
0.90 [0.70-1.14] [ ]<br />
0.80 [0.51-1.26]<br />
0.83 [0.54-1.27]<br />
0.91 [0.55-1.50]<br />
0.24<br />
0.96<br />
0.38<br />
0.34<br />
0.39<br />
0.70<br />
revascularization 256 (25.0%) 192 (26.6%) 0.92 [0.77-1.12] 0.41<br />
NNew-onset tDM DM 7/645 (1.1%) (1 1%) 12/418 (2.9%) 037[0150 0.37 [0.15-0.94] 94] 0.04
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