Wolfgang Kreyling - NanoImpactNet

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NP Trafficking across Lung Epithelium inhalation AM HelmholtzZentrum münchen German Research Center for EnvironmentalHealth Airway epithelium Acinus Rapid translocation from surface Institute of Lung Biology & Disease NP clearance Airways NP re-entrainment Alveolar epithelium Semmler-Behnke et al., EHP 2007 Focus Network Nanoparticles and Health
NP Trafficking across Lung Epithelium interstitium Epithelial lining layer blood erythrocyte • Translocation into blood is a minor transport mechanism Courtesy P. Gehr • But relocation from the epithelial surface to into the epithelium and interstitium is a prominant transport mechanism including re-entrainment of NP back to the epithelial surface + macrophage-mediated clearance towards the larynx HelmholtzZentrum münchen German Research Center for EnvironmentalHealth Institute for Inhalation Biology Ir NP: Semmler-Behnke et al., 2007 Focus Network Nanoparticles and Health
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Wolfgang Kreyling - NanoImpactNet

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