Classic BILAG Index

1. Any one of the Category A criteria above
2. Proteinuria
(a) urinary dipstick which has risen by 1+ or more to at least 2+, or
(b) 24 hour urinary protein rising from > 1g by >50% but 130 µmol/l and having risen to 115% of previous
value
Category C
One of the following:
24 hour urinary protein > 0.25g
Urinary dipstick 1+ or more
Rising blood pressure, defined as
(i) systolic rise of > 30mm and
(ii) diastolic rise of >15mm and
(iii) the recorded values are > 140/90)
Category D
Previous involvement
Category E
No previous involvement
Haematological
Category A
One of the following:
White cell count < 1000
Platelet count < 25
Haemoglobin < 8
Category B
One of the following:
White cell count < 2500
Platelet count < 100
Haemoglobin < 11
Coombs Test positive and evidence of active haemolysis, e.g. raised
bilirubin +/- increased Reticulocyte Count
Category C
One of the following:
White cell count < 4000
Platelet count < 150
Lymphocyte count < 1500
Coombs Test positive but no evidence of active haemolysis
Evidence of circulating lupus anticoagulant or other antiphospholipid
antibody
Category D
Previous involvement
Category E
No previous involvement
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