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INcontrol And The BioGienie - Fort Richard Laboratories Ltd

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<strong>INcontrol</strong> <strong>And</strong> <strong>The</strong><br />

<strong>BioGienie</strong><br />

.


History<br />

• <strong>INcontrol</strong>, supports a range of infection<br />

control products supported across<br />

Australasia by <strong>Fort</strong> <strong>Richard</strong> <strong>Laboratories</strong><br />

<strong>Ltd</strong> and Able Scientific.


Backed by renowned companies<br />

in Australia and New Zealand<br />

• <strong>Fort</strong> <strong>Richard</strong> – a family business with facilities in<br />

Auckland & Melbourne operating since 1974<br />

specializing in the manufacture and supply of culture<br />

media and related microbiology consumables to<br />

clinical laboratories/hospitals throughout new<br />

Zealand and Australia. Many years experience in<br />

supplying products for the surveillance of HAI’s.<br />

• Able Scientific – a family business based in Perth WA<br />

since 1990 supplying Life Science/biotechnology<br />

products to Animal Research Facilities/Universities<br />

throughout Australasia.


Global alliances in Healthcare<br />

• <strong>Fort</strong> <strong>Richard</strong> acquired the Biogenie agency for Australasia<br />

following contact with parent company Hygienics<br />

Biosecurity at Medica 2009, recognizing the need to move<br />

into prevention of HAI’s as well as surveillance.<br />

• In order to best serve both Australia and New Zealand <strong>Fort</strong><br />

<strong>Richard</strong> has partnered with Able Scientific to represent the<br />

Biogenie and several infection control products already<br />

distributed by Able Scientific. This range of products forms<br />

our brand <strong>INcontrol</strong>.<br />

• Personnel from both companies received extensive training<br />

on the Biogenie at Alton, UK in April 2010.<br />

• Through our network of distribution facilities in Auckland,<br />

Melbourne, and Perth, we will provide the ultimate in<br />

service and support across Australasia.


<strong>And</strong> now, let us introduce the<br />

<strong>BioGienie</strong>


<strong>BioGienie</strong> - prevention is<br />

better than cure<br />

• <strong>The</strong> most technologically advanced yet simpleto-use<br />

decontamination system on the market<br />

today.<br />

• Built on the successful history of H2O2 room<br />

decontamination by utilizing lower-risk<br />

disinfectant (meaning a much more portable<br />

and available system), easy-to-use intuitive<br />

software, light and maneuverable design<br />

features, and a more effective kill due to the<br />

ionized and nucleated dry-mist vapor.<br />

• All this combines to deliver an affordable inhouse<br />

decontamination system previously<br />

unavailable to healthcare organizations.


<strong>The</strong> Problem – HAI (Healthcare<br />

Acquired Infection) -<br />

• HAI’s cost aproximately $1 billion each<br />

year*<br />

– 175,000 patients infected whilst in hospital<br />

each year<br />

• 5 days extra days in hospital<br />

• A patient costs $2 - 20k extra to treat<br />

• Litigation increasing<br />

• ~20% mortality<br />

• A very emotive subject


<strong>The</strong> Problem – HAI (Healthcare<br />

Acquired Infection)<br />

• Common Pathogens include:<br />

• MRSA<br />

• Clostridium Difficile *<br />

• Acinetobacter<br />

• Norovirus<br />

• VRE/ESBL


<strong>The</strong> Problem – HAI (Healthcare<br />

Acquired Infection) - Australia<br />

• A report released by professor Graves in<br />

September 2009 estimates that “the<br />

annual direct cost of treating HAI<br />

(Hospital Acquired infections) was close<br />

to $1 billion, and that improving<br />

infection control could save roughly<br />

$600 million”


<strong>The</strong> Problem – HAI (Healthcare<br />

Acquired Infection) - Australia<br />

• Latest news in Australia has the press saying “A stomach<br />

bug that has killed thousands in Canada, USA, Britain &<br />

Europe has been found in Australia. It is known as “the<br />

Quebec strain of Clostridium difficile’ & does not respond<br />

to the alcoholic hand cleanser now used throughout<br />

Australia’s hospitals. A full hand wash with disinfectant<br />

soap & water, isolation of patients & disinfecting wards is<br />

required to prevent it spreading. Australia is ill-prepared if<br />

there is a spread from the 3 patients confirmed in<br />

Melbourne’s Epworth hospital. Only two laboratories in<br />

Australia - In Sydney & Perth – can positively identify this<br />

serious bug, but moves are afoot to enable<br />

microbiologists in each state to rapidly identify any<br />

outbreak.”


Our Solution – Biogienie<br />

• A Hydrogen Peroxide Dry Mist Vapour<br />

Robot<br />

– Effective<br />

– Safe<br />

– Simple to Use<br />

– Inexpensive


Decontamination - Challenges<br />

– Normal cleaning methods not enough<br />

• Limited effectiveness<br />

• Pathogen resistance<br />

• Recontamination<br />

• Costly Downtime<br />

– High risk alternatives<br />

• Ozone gas<br />

• Ethylene oxide gas<br />

• High concentration H2O2 vapour<br />

RECURRENT CYCLE<br />

OF CONTAMINATION<br />

SURFACE<br />

AIR


Effective<br />

• Clinically proven against major pathogens<br />

(spores, bacteria, viruses and fungi)<br />

• Ionised & nucleated dry mist<br />

– Very efficient dispersal of disinfectant<br />

– Smaller dry zone than competitors<br />

• Single unit decontaminates 4m³ - 200m³<br />

– Multiple units used for larger areas


• Biocidal disinfectant<br />

Safe<br />

– Uses Hyproxil Active - 6% H2O2 / 60ppm Ag+<br />

• Much lower H 2O 2 level then competitors (can be<br />

>30%)<br />

• Complies with EEC 98/8 standard<br />

• Eliminates Bio Immunity<br />

• Clinically proven results<br />

• Sealed recyclable cartridges<br />

– Avoids risk of spillage<br />

– Environmentally responsible


• Built in Safety<br />

• Clear warning lights<br />

Safe<br />

• Safety sensors monitor key areas e.g. liquid leak<br />

• Light and manoeuvrable<br />

• Weighs just 39kg<br />

• Built for ease of movement<br />

• Operator friendly<br />

• User panel at optimum height<br />

• Easy to load Hyproxil Active<br />

cartridge


Simple to use<br />

• Program via colour touch screen<br />

– Set operation for :<br />

• Flow rate allows room sizes from 4 m³ to 200 m³<br />

• Number of ml per m³ dosage<br />

• Level of concentration (valuable for pathogen<br />

variants)<br />

• Pre-programmed rooms (quick set up)<br />

– Multi–level security and downloadable audit trail


Inexpensive<br />

• For the cost of approximately 3 HAI<br />

cases, you can own a Biogienie.<br />

• We have a flexible approach to<br />

ownership offering, outright buy, rent-toown,<br />

and rental.<br />

• Ongoing consumable costs from $625.00<br />

per 2000 m3 of room space<br />

decontaminated


Some Current <strong>BioGienie</strong> Users<br />

National Blood Service


Biogienie - the Internationally<br />

proven solution<br />

Nottingham University Hospitals NHS Trust<br />

“50% reduction in C.diff rates since introduction Dry Mist HPV”<br />

University Hospitals of Leicester NHS Trust<br />

“Major contributor to 65% reduction in C.diff rates”<br />

Kettering General Hospital NHS Trust<br />

“Substantial reduction in patients relapsing with C.diff in isolation<br />

rooms since introducing Dry Mist HPV”<br />

Sandwell Hospital, Birmingham<br />

“After vaporisation we had big reductions in incidences of recurrent<br />

C.diff”<br />

Southend Teaching Hospitals NHS Trust<br />

“Prior to the use of Dry Mist HPV micro-organisms were noted.<br />

Post Dry Mist HPV no micro-organisms were noted after 48 hours”


Biogienie - backed by clinical studies<br />

• In a recent study, hydrogen peroxide vapour<br />

decontamination was 82% more effective at eradicating C.<br />

difficile than conventional wiping and disinfecting using<br />

hypochlorite.<br />

• A Journal of Hospital Infection study of MRSA showed that<br />

after conventional terminal cleaning, 66% of 124 swabs<br />

yielded MRSA (74% by direct plating), while after hydrogen<br />

peroxide vapour decontamination, only 1 of 85 swabs<br />

yielded MRSA (by enrichment culture only).<br />

• Another study showed 100% elimination of C. difficile<br />

contamination after hydrogen peroxide vapour<br />

decontamination.<br />

• Over half of the UK hospitals have purchased the Biogienie<br />

and attribute a 50% reduction in HAI’s to the use of this<br />

system.


Results: C difficile<br />

C difficile NCTC 11209<br />

C difficile NCTC 11223<br />

C difficile NCTC 11382<br />

Clinical isolates (n=8)<br />

Typical kill rates<br />

4 x 10 6 – 1.8 x 10 7<br />

1.E+08<br />

1.E+07<br />

1.E+06<br />

1.E+05<br />

1.E+04<br />

1.E+03<br />

1.E+02<br />

1.E+01<br />

1.E+00<br />

Pre-exposure<br />

Post-exposure<br />

NCTC 11209 NTCT 11223 NCTC 11382 Clinical isolates<br />

(n=8)


Summary<br />

• <strong>BioGienie</strong> - Next generation technology<br />

– Effective<br />

– Safe<br />

– Simple to Use<br />

– Inexpensive<br />

Available Now

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