Crystal Induced Arthropathy

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Gout ‐ Treatment Acute Attack ACTH 40 units* or Cosyntrophin 0.25 mg May repeat in 12 and 24 hours Would consider in patients with Renal insufficiency DM PUD NPO May allow you to use lower dose of prednisone * J of Rheum 1994;31:803-5
Gout – Uric Acid Lowering Agents Goal ‐ serum uric acid < 6 mg. /dl. Agents available Uricosurics – Probenecid – need 24 hour urine, not as effective with CrCl < 60 Xanthine Oxidase inhibitors Allopurinol and Febuxostat, no 24 hour urine needed, effective in both underexcretors and over producers Treatment may precipitate an attack in about 25% of patients warn patient If an acute attacks occurs while on uric acid lowering agent, treat the attack but continue the drug treatment with prophylactic colchicine or NSAID prevents 85% of these flares
Page 1 and 2: Update on Crystal Related Arthritis
Page 3 and 4: Gout A disorder related to monosod
Page 5 and 6: Gout ‐ Diagnosis Typically acute
Page 7 and 8: Compensated polarized microscopy -
Page 9: Gout in the Older Patient Incidenc
Page 14 and 15: Gout & Related Conditions Hyperten
Page 16 and 17: Hyperuricemia - A Cause of or Marke
Page 18 and 19: So What Should We Do? Should we tr
Page 20 and 21: Gout - Treatment of Acute Attack C
Page 24 and 25: Allopurinol Dose - Initial ‐ 10
Page 26 and 27: Allopurinol Hypersensitivity Syndro
Page 28 and 29: Febuxostat Approved in U.S. for 40
Page 30 and 31: Other Ways to Reduce Risk of Gout
Page 32 and 33: Treatments on the Horizon Acute at
Page 34 and 35: Calcium Pyrophosphate Dihydrate Dep
Page 36 and 37: Clincal Clues to Diagnosis Pseudog
Page 38 and 39: CPPD ‐ Diagnosis Other suggestiv
Page 40 and 41: From the ACR slide collection ©
Page 42: CPPD ‐ Treatment Psuedogout Asp

Crystal Induced Arthropathy

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