Graphical contents list

1198 Contents / Tetrahedron Letters 53 (2012) 1193–1199
Rapid access to pyrido[1,2,5]triazepin-4-ones through intramolecular nucleophilic aromatic substitution pp 1278–1281
Shujuan Jin*, Olivier St-Jean, Sandra I. Baltatu, Vijayaratnam Santhakumar, Mirosław J. Tomaszewski
Novel route to spiropiperidines using N-methyl-4-piperidone, malononitrile and electrophiles pp 1282–1286
Neelakandan Vidhya Lakshmi, G. A. Suganya Josephine, Paramasivan T. Perumal*
R 1
N
H 2
NC
NC
HN
NC
N
R
CN
H
O
N
N
R1
NC
N
R
CN
O
O
N
NC
NC
H N 2
+
CN
CN
NEt ethanol,
3
reflux R1 N
NC N
N
R
O
O
R 1
N
H 2
HN
O
NC
N
CN
H
O
N
N
N
H 2
( or )
HN
( or )
R
H
R2CHO R2 Lewis acid-assisted olefin cross-metathesis reaction: an efficient approach for the synthesis of glycosidicpyrroloquinolinone
based novel building blocks of camptothecin and evaluation of their antitumor activity
Lingaiah Nagarapu*, Hanmant K. Gaikwad, Rajashaker Bantu, Sheeba Rani Manikonda, C. Ganesh Kumar, Sujitha Pombala
N
O
N
+ H
O
R1 R2
R3
Ti(O i Pr)4 30 mol %
[Cl2(Im)(PCy3)Ru=CHPh],
10 mol %, CH2Cl2, 40 °C.
The synthesis of antitumor active glycosidic-pyrroloquinolinone based novel building blocks of camptothecin via Lewis acid-assisted olefin crossmetathesis
reaction.
N
N
O
H
R1
O
R2
R3
O
NC
CN
N
N
pp 1287–1291
Synthesis of a,a-dideutero-b-amino esters pp 1292–1295
S. Chandrasekhar*, Mrunal Pendke, Chandrashekar Muththe, Srirama Murthy Akondi, Prathama S. Mainkar
R
N R'
H
CD 3CN
LDA
THF
-78 °C
R
HN R'
R=Ar,Alkyl;R'=Bn,RorS
CN
D D
Ph
H 2SO 4
CH 3OH
R
HN R'
COOCH 3
D D