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Mops/Tris/Sds running buffer for Variogel - anamed Elektrophorese ...

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Safety Safety data data sheet sheet in in accordance accordance with with Regulation Regulation (EC) (EC) No No 11907/2006<br />

1 907/2006<br />

Revision: Revision: 30 30.04.201 30 .201 .2011 .201<br />

Version: Version: 00 0006 00<br />

Replacement of version 00 0005 00<br />

of 29 29.01.20 29 .20 .2010 .20<br />

1. 1. Identification Identification of of the the substance/mixture substance/mixture and and of of the the company/undertaking<br />

company/undertaking<br />

1.1 1.1 Product Product Product Product identifier identifier identifier identifier<br />

Trade name <strong>Mops</strong>-<strong>Tris</strong> <strong>Mops</strong><br />

<strong>Mops</strong> <strong>Tris</strong> <strong>Tris</strong>-SDS <strong>Tris</strong> SDS SDS Running Running Buffer<br />

<strong>for</strong> <strong>for</strong> VarioGel VarioGel<br />

® (20x (20x Concentr Concentrate)<br />

Concentr ate)<br />

Product number anam0031<br />

Item code VM/03<br />

Formulation MTRB<br />

Formulation number 11/05<br />

1.2 1.2 Relevant Relevant Relevant Relevant identified identified identified identified uses uses uses uses of of of of the the the the substance substance substance substance or or or or mixture mixture mixture mixture and and and and uses uses uses uses advised advised advised advised against against against against<br />

The product is used <strong>for</strong> electrophoresis in analytical laboratories.<br />

1.3 1.3 Details Details Details Details of of of of the the the the supplier supplier supplier supplier of of of of the the the the safety safety safety safety data data data data sheet sheet sheet sheet<br />

<strong>anamed</strong> <strong>Elektrophorese</strong> GmbH<br />

Ringstraße 4<br />

D-64401 Gross-Bieberau<br />

Telephone: int+49-(0)6162-809840<br />

e-mail-address of the competent person responsible <strong>for</strong> this Safety Data Sheet:<br />

urban-finking.gefstoff@t-online.de<br />

Technical contact:<br />

<strong>anamed</strong> <strong>Elektrophorese</strong> GmbH<br />

Frau Dr. Vera Kreis / Herr Dieter Lindenberger<br />

Telephone int+49-(0)6162-809840<br />

Fax int+49-(0)6162-8098420<br />

1.4 1.4 Emergency Emergency Emergency Emergency telephone telephon telephon telephone<br />

e e number number number number<br />

Poison Control Center Mainz (Giftin<strong>for</strong>mationszentrum Mainz) or local poison centers<br />

Telephone int+49-(0)6131 19 2 40<br />

2. 2. Hazards Hazards identification<br />

identification<br />

2.1 2.1 Classification Classification Classification Classification of of of of the the the the substance substance substance substance or or or or mixture mixture mixture mixture<br />

The product does not meet the criteria <strong>for</strong> a classification as hazardous in accordance with the current version of<br />

Directive 1999/45/EC.<br />

2.2 2.2 Label Label Label Label elements elements elements elements<br />

Symbol(s) of danger: Not required<br />

Indication(s) of danger: Not required<br />

Hazardous component(s) to be indicated on label: Not required<br />

R phrases: Not required<br />

S phrases: Not required<br />

Special labelling <strong>for</strong> certain mixtures:<br />

In accordance with annex V C. 1. of Directive 1999/45/EC the label on the packaging of mixtures mixtures not not intended<br />

<strong>for</strong> <strong>for</strong> <strong>for</strong> the the the general general public public must bear the following inscription:<br />

“Safety “Safety data data sheet sheet available available <strong>for</strong> <strong>for</strong> professional professional user user on on request.”<br />

request.”<br />

Remarks:<br />

The normal safety precautions <strong>for</strong> handling of chemicals must be observed.<br />

2.3 2.3 Other Other Other Other hazards hazards hazards hazards<br />

Possible health hazard if not used correctly.<br />

Irritant effect on eyes and skin cannot be ruled out.<br />

The product is classified as hazardous to water.<br />

The mixture does not meet the criteria <strong>for</strong> PBT or vPvB.<br />

Page 1 of 8


Safety Safety data data sheet sheet in in accordance accordance accordance with with Regulation Regulation (EC) (EC) No No 1907/200 1907/2006 1907/200<br />

Page 2 of 8<br />

Trade name: <strong>Mops</strong> <strong>Mops</strong>-<strong>Tris</strong> <strong>Mops</strong><br />

<strong>Tris</strong> <strong>Tris</strong>-SDS <strong>Tris</strong> SDS Running Buffer <strong>for</strong> Va VarioGel Va<br />

rioGel ® (20x (20x Concentrate)<br />

Concentrate)<br />

Company/Undertaking: <strong>anamed</strong> <strong>Elektrophorese</strong> <strong>Elektrophorese</strong> GmbH<br />

Ringstraße Ringstraße 44,<br />

4 , DD-64<br />

D 64 6440<br />

401 40 1 Gross Gross-Bieberau<br />

Gross<br />

Bieberau<br />

Telephone: int+49 int+49-(0)61<br />

int+49<br />

(0)61 (0)6162<br />

62-809840<br />

62 809840 Revision: 30.04.2011<br />

Product number: anam0031<br />

3. Composition/in<strong>for</strong>mation Composition/in<strong>for</strong>mation on on ingredients<br />

ingredients<br />

3.2 Mixtures Mixtures Mixtures Mixtures<br />

3.2.1 Characterisation<br />

Characterisation<br />

Characterisation<br />

Characterisation<br />

Ready-to use <strong>buffer</strong> solution (concentrate) <strong>for</strong> mops-tris-sds applications, an aqueous mixture containing several<br />

special substances.<br />

3.2.2 Substances Substances Substances Substances presenting presenting presenting presenting a a a a health/environmental health/environmental health/environmental health/environmental hazard hazard hazard hazard within within within within the the the the meaning meaning meaning meaning of of of of Directive Directive Directive Directive 67/548/EEC<br />

67/548/EEC<br />

67/548/EEC<br />

67/548/EEC<br />

CAS CAS No EC EC No No<br />

Identification Identification<br />

% by weight Classification Indication(s)<br />

of f f danger danger<br />

77-86-1 201-064-4 trometamol < 15 Xi; R36/38 Irritant<br />

151-21-3 205-788-1 sodium dodecyl sulfate < 5 F; R11 Highly flammable<br />

Xn; R21/22<br />

Harmful<br />

Xi; R36/37/38<br />

Irritant<br />

See ee subsection subsection 2.2 2.2 <strong>for</strong> further details details. details<br />

. . Full Full text text of of of the the R R phrases phrases see see sub subsection sub<br />

section section 16.2.<br />

3.2.3 Substances Substances Substances Substances presenting presenting presenting presenting a a a a health/environmental health/environmental health/environmental health/environmental hazard hazard hazard hazard within within within within the the the the meaning meaning meaning meaning of of of of Regulation Regulation Regulation Regulation (EC) (EC) (EC) (EC) No No No No 1272/2008<br />

1272/2008<br />

1272/2008<br />

1272/2008<br />

CAS CAS No EC EC No No<br />

Identification % by weight weight Classification<br />

Classification<br />

77-86-1 201-064-4 trometamol < 15 Eye Irrit. 2; H319<br />

Skin Irrit. 2; H315<br />

151-21-3 205-788-1 sodium dodecyl sulfate < 5 Flam. Sol. 2; H228<br />

Acute Tox. 3; H311<br />

Acute Tox. 4; H302<br />

STOT SE 3; H335<br />

Skin Irrit. 2; H315<br />

Eye Irrit. 2; H319<br />

3.2.4 See See number number 16.4.2 16.4.2 <strong>for</strong> <strong>for</strong> further further further details. details. Full Full text text of of of the hazard statements statements see see subsection subsection 16. 16.3. 16.<br />

Substances<br />

Substa Substa Substances<br />

nces nces which which which which are are are are assigned assigned assigned assigned Community Community Community Community workplace workplace workplace workplace exposure exposure exposure exposure limits limits limits limits and and and and which which which which are are are are not not not not already already already already included included included included under under under under<br />

points points points points 3333.2.2 .2.2 .2.2 .2.2 and and and and 3.2.3 3.2.3 3.2.3 3.2.3 (see (see (see (see also also also also SSSSection ection ection ection 8.) 8.) 8.) 8.)<br />

No substances.<br />

3.3 3.3 Additional Additional Additional Additional in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

None.<br />

4. First First aid aid aid measures<br />

measures<br />

4.1 Description Description Description Description of of of of first first first first aid aid aid aid measures measu measu measures<br />

res res<br />

4.1.1 General General General General in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

Remove contaminated clothing immediately and wash be<strong>for</strong>e reuse.<br />

Emergency eyewash should be provided in the immediate working surroundings.<br />

4. 4.1. 4.<br />

1. 1.2 1. In In In In case case case case of of of of inhalation inhalation inhalation inhalation<br />

Remove the casualty into fresh air. In the event of symptoms take medical treatment.<br />

4. 4.1. 4.<br />

1. 1.3 1. In In In In case case case case of of of of contact contact contact contact with with with with skin skin skin skin<br />

In case of contact with eyes rinse thoroughly with plenty of water.<br />

4. 4.1. 4.<br />

1. 1.4 1. In In In In case case case case of of of of contact contact contact contact with with with with eyes eyes eyes eyes<br />

In case of contact with eyes, rinse immediately with plenty of flowing water <strong>for</strong> 10 to 15 minutes holding eyelids<br />

apart and seek medical advice. Remove contact lenses, if present and easy to do.<br />

4. 4.1. 4.<br />

1. 1.5 1. In In In In case case case case of of of of ingestion ingestion ingestion ingestion<br />

Call physician immediately.<br />

4.2 Most Most Most Most important important important important symptoms symptoms symptoms symptoms and and and and effects, effects, effects, effects, both both both both acute acute acute acute and and and and delayed delayed delayed delayed<br />

Irritant effect on eyes and skin cannot be ruled out.<br />

4.3 Indication Indication Indication Indication of of of of any any any any immediate immediate immediate immediate medical medical medical medical attention attention attention attention and and and and special special special special treatment treatment treatment treatment needed needed needed needed<br />

No in<strong>for</strong>mation available.<br />

5. 5. Firefighting Firefighting measures<br />

measures<br />

5.1 5.1 EEEExtinguishing xtinguishing xtinguishing xtinguishing media media media media<br />

5.1.1 5.1.1 Suitable Suitable Suitable Suitable extinguishing extinguishing extinguishing extinguishing media media media media<br />

Water spray jet, carbon dioxide, dry powder.<br />

5. 5.1. 5. 1. 1.2 1. Unsuitable Unsuitable Unsuitable Unsuitable extinguishing ee<br />

extinguishing<br />

xtinguishing xtinguishing media media media media<br />

Full water jet.<br />

5. 5.2 5. Special Special Special Special hazards hazards hazards hazards arising arising arising arising from from from from the the the the substance substance substance substance or or or or mixture mixture mixture mixture<br />

In the event of fire the following can be released: hydrocarbons, carbon oxides, nitrogen oxides, nitrous gases,<br />

sulfur oxides. Risk of <strong>for</strong>mation of toxic pyrolysis products.<br />

5. 5.3 5. Advice Advice Advice Advice <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> firefighters firefighters firefighters firefighters<br />

Wear self-contained breathing apparatus.<br />

Do not inhale explosion and combustion gases. Cool endangered containers with water spray jet.<br />

Fire residues and contaminated firefighting water must be disposed of in accordance with the local regulations.


Safety Safety data data sheet sheet in in accordance accordance accordance with with Regulation Regulation (EC) (EC) No No 1907/200 1907/2006 1907/200<br />

Page 3 of 8<br />

Trade name: <strong>Mops</strong> <strong>Mops</strong>-<strong>Tris</strong> <strong>Mops</strong><br />

<strong>Tris</strong> <strong>Tris</strong>-SDS <strong>Tris</strong> SDS Running Buffer <strong>for</strong> Va VarioGel Va<br />

rioGel ® (20x (20x Concentrate)<br />

Concentrate)<br />

Company/Undertaking: <strong>anamed</strong> <strong>Elektrophorese</strong> <strong>Elektrophorese</strong> GmbH<br />

Ringstraße Ringstraße 44,<br />

4 , DD-64<br />

D 64 6440<br />

401 40 1 Gross Gross-Bieberau<br />

Gross<br />

Bieberau<br />

Telephone: int+49 int+49-(0)61<br />

int+49<br />

(0)61 (0)6162<br />

62-809840<br />

62 809840 Revision: 30.04.2011<br />

Product number: anam0031<br />

6. 6. 6. Accidental release measures<br />

6.1 6.1 Personal Personal Personal Personal precautions,,,, precautions<br />

precautions<br />

precautions protective protective protective protective equipment equipment equipment equipment and and and and emergency emergency emergency emergency procedures<br />

procedures<br />

procedures<br />

procedures<br />

6.1.1 6.1.1 For For For For non----emergency non non non emergency emergency emergency personnel personnel personnel personnel<br />

Ensure adequate ventilation. Use personal protective clothing.<br />

Use respiratory protection if exposed to vapours. Keep away from unprotected people.<br />

6.1.2 6.1.2 For For For For emergency emergency emergency emergency responders responders responders responders<br />

For suitable fabric <strong>for</strong> personal protective clothing see Section 8.<br />

6.2 6.2 Environmental Environmental Environmental Environmental precautions<br />

precautions<br />

precautions<br />

precautions<br />

Do not discharge into the drains, the aquatic environment and soil.<br />

6.3 6.3 Methods Methods Methods Methods and and and and material material material material <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> containment containment containment containment and and and and cleaning cleaning cleaning cleaning up up up up<br />

Pick up with suitable material. Dispose of absorbed material in accordance with the regulations.<br />

Send in suitable containers <strong>for</strong> recovery or disposal. Flush away residues with plenty of water.<br />

6.4 6.4 Reference Reference Reference Reference to to to to other other other other sections sections sections sections<br />

For personal protective equipment see also Section 8.<br />

For disposal considerations see also Section 13.<br />

7. 7. Handling Handling and and storage<br />

storage<br />

7.1 7.1 Precautions Precautions Precautions Precautions <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> safe safe safe safe handling hh<br />

handling<br />

andling andling<br />

7.1.1 7.1.1 Advice Advice Advice Advice on on on on safe safe safe safe handling handling handling handling<br />

The normal safety precautions <strong>for</strong> handling of chemicals must be observed.<br />

Avoid contact with eyes and skin.<br />

Comply with the minimum standards in accordance with TRGS 5001 .<br />

7.1.2 7.1.2 Advice Advice Advice Advice on on on on general general general general occupational occupational occupational occupational hygiene hygiene hygiene hygiene<br />

Do not inhale vapours. Avoid contact with eyes and skin.<br />

At work do not eat, drink, smoke or take drugs. Remove contaminated clothing immediately and wash be<strong>for</strong>e reuse.<br />

Wash hands be<strong>for</strong>e breaks and after work. Use barrier skin cream.<br />

Emergency eyewash should be provided in the immediate working surroundings.<br />

7.2 7.2 Conditions Conditions Conditions Conditions <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> safe safe safe safe storage, storage, storage, storage, including including including including any any any any incompatibilities<br />

incompatibilities<br />

incompatibilities<br />

incompatibilities<br />

7.2 7.2.1 7.2 .1 Advice Advice Advice Advice on on on on protection protection protection protection against against against against fire fire fire fire and and and and explosion explosion explosion explosion<br />

None.<br />

7.2. 7.2.2 7.2. Requirements Requirements Requirements Requirements <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> storage storage storage storage rooms rooms rooms rooms and and and and vessels vessels vessels vessels<br />

Keep container tightly closed. Keep in a cool place.<br />

7.2. 7.2.3 7.2. Advice Advice Advice Advice on on on on storage storage storage storage compatibility<br />

compatibility<br />

compatibility<br />

compatibility<br />

Do not store together with strong oxidising agents.<br />

The in<strong>for</strong>mation about joint storage given in Table 2 of TRGS 5101 must be observed.<br />

7.2. 7.2.4 7.2. Further Further Further Further in<strong>for</strong>mation in<strong>for</strong>mation in<strong>for</strong>mation in<strong>for</strong>mation on on on on storage storage storage storage conditions conditions conditions conditions<br />

None.<br />

7.2. 7.2.5 7.2. Stor Storage Stor Storage<br />

age age class class class class (<strong>for</strong> (<strong>for</strong> (<strong>for</strong> (<strong>for</strong> Germany Germany Germany Germany only) only) only) only)<br />

LGK 12 (non-combustible liquids) in accordance with TRGS 5101 .<br />

7.3 7.3 Specific Specific Specific Specific end end end end use(s) use(s) use(s) use(s)<br />

The product is only intended <strong>for</strong> the uses mentioned under subsection 1.2.<br />

8. 8. Exposure Exposure controls/ controls/personal controls/ ersonal protection<br />

protection<br />

8.1 8.1 Control Control Control Control parameterssss<br />

parameter parameter parameter<br />

The product does not contain substances <strong>for</strong> which there are exposure limit values.<br />

8.2 8.2 Exposure Exposure Exposure Exposure controls controls controls controls<br />

8.2.1 8.2.1 Appropriate Appropriate Appropriate Appropriate engineering engineering engineering engineering controls controls controls controls<br />

Technical measures and appropriate working operations should be given priority over the use of personal protective<br />

equipment.<br />

See also subsection 7.1.<br />

8.2.2 8.2.2 Individual Individual Individual Individual protection protection protection protection measures, measures, measures, measures, such such such such as as as as personal personal personal personal protective protective protective protective equipment equipment equipment equipment<br />

8.2.2.1 8.2.2.1 Eye/face Eye/face Eye/face Eye/face protection protection protection protection<br />

Tightly fitting safety glasses in accordance with EN 166 (i.e. safety glasses with side shields).<br />

8.2.2.2 8.2.2.2 Skin Skin Skin Skin protection prot prot protection<br />

ection ection<br />

Hand protection protection: protection<br />

In case of operations where skin contact is possible. wear suitable protective gloves.<br />

Chemical protective gloves needs to be selected specifically <strong>for</strong> the workplace, depending on concentrations and<br />

quantities of the hazardous substances handled. In the cases of special applications, it is recommended to check the<br />

chemical resistance with the manufacturer of the gloves.<br />

The protective gloves to be used must comply with the specifications of the standard EN 374.<br />

Body Body protec protection:<br />

protec tion:<br />

Closed work clothing.


Safety Safety data data sheet sheet in in accordance accordance accordance with with Regulation Regulation (EC) (EC) No No 1907/200 1907/2006 1907/200<br />

Page 4 of 8<br />

Trade name: <strong>Mops</strong> <strong>Mops</strong>-<strong>Tris</strong> <strong>Mops</strong><br />

<strong>Tris</strong> <strong>Tris</strong>-SDS <strong>Tris</strong> SDS Running Buffer <strong>for</strong> Va VarioGel Va<br />

rioGel ® (20x (20x Concentrate)<br />

Concentrate)<br />

Company/Undertaking: <strong>anamed</strong> <strong>Elektrophorese</strong> <strong>Elektrophorese</strong> GmbH<br />

Ringstraße Ringstraße 44,<br />

4 , DD-64<br />

D 64 6440<br />

401 40 1 Gross Gross-Bieberau<br />

Gross<br />

Bieberau<br />

Telephone: int+49 int+49-(0)61<br />

int+49<br />

(0)61 (0)6162<br />

62-809840<br />

62 809840 Revision: 30.04.2011<br />

Product number: anam0031<br />

8.2.2.3 8.2.2.3 Respiratory Respiratory Respiratory Respiratory protection protection protection protection<br />

With correct and proper use, and adequate ventilation of the working place, respiratory protection is not required.<br />

In case of inadequate ventilation, and in case of <strong>for</strong>mation of vapours/aerosols, wear respiratory protection.<br />

In<strong>for</strong>mation on appropriate respirator protection is currently not available.<br />

The limitations in wearing time according to the BGR 1902 (rule of the German employers´ liability insurance<br />

association) <strong>for</strong> the use of respirators have to observed.<br />

8.2.2.4 8.2.2.4 8.2.2.4 Thermal Thermal Thermal Thermal hazards hazards hazards hazards<br />

Not relevant.<br />

8.2.3 8.2.3 Environmental Environmental Environmental Environmental exposure exposure exposure exposure controls controls controls controls<br />

See Section 6.<br />

9. 9. 9. Physical Physical and and chemical chemical properties<br />

properties<br />

9.1 9.1 IIIIn<strong>for</strong>mation<br />

n<strong>for</strong>mation n<strong>for</strong>mation<br />

n<strong>for</strong>mation on on on on basic basic basic basic physical physical physical physical and and and and chemical chemical chemical chemical properties properties properties properties<br />

Physical state: liquid<br />

Colour: colourless<br />

Odour: odorless<br />

Odour threshold: no relevant<br />

pH (as supplied): 8.2 – 8.6<br />

pH (of an aqueous solution): not determined<br />

Melting point/freezing point (°C): not determined<br />

Boiling point and boiling range (°C): not determined<br />

Flash point (°C), closed cup: not relevant<br />

Evaporation rate: no data available<br />

Flammability (solid, gas): not relevant<br />

Upper flammability or explosive limit: not relevant<br />

Lower flammability or explosive limit: not relevant<br />

Vapour pressure (20°C) (mbar): no data available<br />

Vapour density (20°C): no data available<br />

Density (g/cm³): not determined<br />

Solubility in water: miscible<br />

Soluble in: not determined<br />

Partition coefficient: n-octanol/water: - 1.56 (trometamol) (external safety data sheet)<br />

1.60 (sodium dodecyl sulfate) (LOGKOW © databank) 3<br />

Auto-ignition temperature (°C): no data available<br />

Decomposition temperature (°C): no data available<br />

Viscosity: no data available<br />

Explosive properties: not explosive<br />

Oxidising properties: not relevant<br />

9.2 9.2 Other Other Other Other in<strong>for</strong>mation in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

None.<br />

10. Stability Stability and reactivity<br />

10.1 10.1 Reactivity Reactivity Reactivity Reactivity<br />

No data available <strong>for</strong> the mixture.<br />

10.2 10.2 Chemical Chemical Chemical Chemical stability stability stability stability<br />

The product is stable under normal ambient and anticipated storage and handling conditions of temperature<br />

and pressure.<br />

10.3 10.3 Possibility Possibility Possibility Possibility of of of of hazardous hazardo hazardo hazardous<br />

us us reactions reactions reactions reactions<br />

Reaction with strong oxidising agents, bases and acids possible.<br />

10.4 10.4 Conditions Conditions Conditions Conditions to to to to avoid avoid avoid avoid<br />

No particular conditions known.<br />

10. 10.5 10.<br />

Materials Materials Materials Materials to to to to avoid avoid avoid avoid<br />

Reaction with strong oxidising agents, bases and acids possible.<br />

10. 10.6 10.<br />

Hazardous Hazardous Hazardous Hazardous decomposition decomposition<br />

decomposition<br />

decomposition products products products products<br />

When used as intended, no hazardous decomposition products known.<br />

For hazardous combustion products see subsection 5.2.


Safety Safety data data sheet sheet in in accordance accordance accordance with with Regulation Regulation (EC) (EC) No No 1907/200 1907/2006 1907/200<br />

Page 5 of 8<br />

Trade name: <strong>Mops</strong> <strong>Mops</strong>-<strong>Tris</strong> <strong>Mops</strong><br />

<strong>Tris</strong> <strong>Tris</strong>-SDS <strong>Tris</strong> SDS Running Buffer <strong>for</strong> Va VarioGel Va<br />

rioGel ® (20x (20x Concentrate)<br />

Concentrate)<br />

Company/Undertaking: <strong>anamed</strong> <strong>Elektrophorese</strong> <strong>Elektrophorese</strong> GmbH<br />

Ringstraße Ringstraße 44,<br />

4 , DD-64<br />

D 64 6440<br />

401 40 1 Gross Gross-Bieberau<br />

Gross<br />

Bieberau<br />

Telephone: int+49 int+49-(0)61<br />

int+49<br />

(0)61 (0)6162<br />

62-809840<br />

62 809840 Revision: 30.04.2011<br />

Product number: anam0031<br />

11. Toxicological in<strong>for</strong>mation<br />

11.1 11.1 In<strong>for</strong>mation In<strong>for</strong>mation In<strong>for</strong>mation In<strong>for</strong>mation on on on on toxicological toxicological toxicological toxicological effects effects effects effects<br />

11.1 11.1.1 11.1 11.1.1<br />

.1 Toxic Toxicokinetics, Toxic Toxicokinetics,<br />

okinetics, okinetics, metabolism metabolism metabolism metabolism and and and and distribution<br />

dis dis distribution<br />

tribution tribution<br />

No data are available <strong>for</strong> the product.<br />

11. 11.1. 11.<br />

1. 1.2 1. Acute Acute Acute Acute effects effects effects effects (acute (acute (acute (acute toxicity, toxicity, toxicity, toxicity, irritation irritation irritation irritation and and and and corrosivity)<br />

corrosivity) corrosivity)<br />

corrosivity)<br />

LD50 rat, oral (mg/kg) > 3000 (trometamol) (RTECS)<br />

1288 (sodium dodecyl sulfate) (RTECS)<br />

> 2000 (4-(morpholino)propanesulfonic acid) (OECD 423)<br />

LD50 rabbit, dermal (mg/kg) 580 (sodium dodecyl sulfate) (IUCLID)<br />

LC50 rat, inhalation (mg/l/4h) No data available.<br />

Irritant effect on skin (rabbit) irritations (sodium dodecyl sulfate) (OECD 404)<br />

Irritant effect on eyes (rabbit) serious irritations (sodium dodecyl sulfate) (OECD 405)<br />

11. 11.1. 11.<br />

1. 1.3 1. Sensitisation<br />

Sensitisation<br />

Sensitisation<br />

Sensitisation<br />

No data available <strong>for</strong> the product.<br />

11. 11.1.4 11.<br />

1.4 CMR CMR CMR CMR effects effects effects effects (carcinogenic<br />

(carcinogen<br />

(carcinogen<br />

(carcinogenic<br />

icity, icity,<br />

ity, ity, mutagenicity, mutagenicity, mutagenicity, mutagenicity, toxicity toxicity toxicity toxicity <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> the the the the reproduction)<br />

reproduction)<br />

reproduction)<br />

reproduction)<br />

Carcinogenicity No data available.<br />

Mutagenicity No data available.<br />

Toxicity <strong>for</strong> the reproduction No data available.<br />

11. 11.1.5 11.<br />

1.5 Comprehensive Comprehensive Comprehensive Comprehensive evaluation evaluation evaluation evaluation of of of of the the the the CMR CMR CMR CMR properties properties properties properties of of of of substances substances substances substances subject subject subject subject to to to to registration<br />

registration<br />

registration<br />

registration<br />

No data available.<br />

11.1.6 11.1.6 In<strong>for</strong>mation In<strong>for</strong>mation In<strong>for</strong>mation In<strong>for</strong>mation on on on on likely likely likely likely routes routes routes routes of of of of exposure exposure exposure exposure<br />

Irritant effect on eyes and skin cannot be ruled out if the product is not used correctly.<br />

11.1.7 11.1.7 Symptoms Symptoms Symptoms Symptoms related related related related to to to to the the the the physical, physical, physical, physical, chemical chemical chemical chemical and and and and toxicological toxicological toxicological toxicological characteristics<br />

characteristics<br />

characteristics<br />

characteristics<br />

The product has not been tested.<br />

11.1.8 11.1.8 Delayed Delayed Delayed Delayed and and and and immediate immediate immediate immediate effects effects effects effects as as as as well well well well as as as as chronic chronic chronic chronic effects effects effects effects from from from from short short short short and and and and lon longggg----term lon lon term term term exposure exposure exposure exposure<br />

Irritant effect on eyes and skin cannot be ruled out.<br />

11.1.9 11.1.9 Interactive Interactive Interactive Interactive efects efects efects efects<br />

No in<strong>for</strong>mation on interactive effects available <strong>for</strong> the product.<br />

11. 11.1.10 11.<br />

1.10 1.10General General General General remarks remarks remarks remarks<br />

The product has not been tested.<br />

12. 12. Ecological in<strong>for</strong>mation<br />

12. 12.1 12.<br />

TTTToxicity oxicity oxicity oxicity<br />

Aquatic Aquatic Aquatic toxicity toxicity: toxicity<br />

LC50 (fish) 4.5 mg/l/96 h (Lepomis macrochirus; bluegill sunfish)<br />

(sodium dodecyl sulfate) (IUCLID)<br />

> 1000 mg/l/96 h (Danio rerio; zebrafish) (OECD 203)<br />

(4-(morpholino)propanesulfonic acid)<br />

EC50 (daphnia) 6 mg/l/48 h (Daphnia magna)<br />

(sodium dodecyl sulfate)<br />

(IUCLID)<br />

> 1000 mg/l/48 h (Daphnia magna) (OECD 202)<br />

IC50 (algae) 53 mg/l/72 h<br />

(4-(morpholino)propanesulfonic acid)<br />

(Desmodesmus subspicatus) (IUCLID)<br />

(sodium dodecyl sulfate)<br />

12. 12.2 12.<br />

Behaviour in sewage works:<br />

works:<br />

Treat by state-of-the-art technology be<strong>for</strong>e discharging into drains.<br />

Persistence Persistence Persistence Persistence and and and and degradability<br />

degradability<br />

degradability<br />

degradability<br />

The product has not been tested.<br />

Sodium dodecyl sulfate: biodegradation 90%, exposure time 28 days (OECD 301 E) (external safety data sheet).<br />

4-(morpholino)propanesulfonic acid:<br />

biodegradation 68%, exposure time 28 days (OECD 301 D) (external safety data sheet).<br />

12. 12.3 12.<br />

Bioaccumulative Bioaccumulative Bioaccumulative Bioaccumulative potential potential potential potential<br />

Partition coefficient n-octanol/water: - 1.56 (trometamol) (external safety data sheet)<br />

Partition coefficient n-octanol/water: 1.60 (sodium dodecyl sulfate ) (LOGKOW © databank) 3<br />

12.4 12.4<br />

Bioaccumulation is not expected.<br />

Mobility Mobility Mobility Mobility in in in in soil soil soil soil<br />

The product has not been tested.<br />

12.5 12.5 Results Results Results Results of of of of PBT PBT PBT PBT and and and and vPvB vPvB vPvB vPvB assessment<br />

assessment<br />

assessment<br />

assessment<br />

No data available.<br />

12.6 12.6 Other Other Other Other adverse adverse adverse adverse effects effects effects effects<br />

Ozone depletion potential No data available.<br />

Photochemical ozone creation potential No data available.<br />

Global warming potential No data available.<br />

AOX-hint Not to apply.


Safety Safety data data sheet sheet in in accordance accordance accordance with with Regulation Regulation (EC) (EC) No No 1907/200 1907/2006 1907/200<br />

Page 6 of 8<br />

Trade name: <strong>Mops</strong> <strong>Mops</strong>-<strong>Tris</strong> <strong>Mops</strong><br />

<strong>Tris</strong> <strong>Tris</strong>-SDS <strong>Tris</strong> SDS Running Buffer <strong>for</strong> Va VarioGel Va<br />

rioGel ® (20x (20x Concentrate)<br />

Concentrate)<br />

Company/Undertaking: <strong>anamed</strong> <strong>Elektrophorese</strong> <strong>Elektrophorese</strong> GmbH<br />

Ringstraße Ringstraße 44,<br />

4 , DD-64<br />

D 64 6440<br />

401 40 1 Gross Gross-Bieberau<br />

Gross<br />

Bieberau<br />

Telephone: int+49 int+49-(0)61<br />

int+49<br />

(0)61 (0)6162<br />

62-809840<br />

62 809840 Revision: 30.04.2011<br />

Product number: anam0031<br />

12. 12.7 12.<br />

Further Further Further Further in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

Chemical oxygen demand (COD) No data available.<br />

Biochemical oxygen demand (BOD5) No data available.<br />

The product is classified as hazardous to water.<br />

Contains according to the <strong>for</strong>mulation <strong>for</strong>mulation following heavy metals and compounds compounds of of EC EC-Directives EC<br />

Directives 2006/11/EC<br />

2006/11/EC<br />

2006/11/EC<br />

and 80/68/EEC:<br />

None.<br />

13. 13. Disposal Disposal considerati considerations<br />

considerati ons<br />

13.1 13.1 Waste Waste Waste Waste treatment treatment treatment treatment methods methods methods methods<br />

Waste disposal according to official state regulations. Consult the local waste disposal expert about waste disposal.<br />

Sewage disposal must be avoided.<br />

Disposal Disposal operations/recovery operations/recovery operations operations according according to to Directive Directive 2008/ 2008/98/EC<br />

2008/ 98/EC<br />

Disposal operations: D 9 Physico-chemical treatment<br />

Recovery operations: R 3 Recycling/reclamation of organic substances which are not used<br />

as solvents<br />

Properties of waste which render it hazardous in accordance with Annex III of Directive 20 2008/98/E 20 2008/98/E<br />

08/98/EC 08/98/E<br />

Not relevant.<br />

13.1 13.1.1 13.1 .1 Product Product Product Product / / / / unused unused unused unused product product product product<br />

Waste disposal corresponding to European Waste Catalogue. Wastes must be classified with respect to their origin<br />

and depending on different processing steps. The waste codes mentioned as follows are only constituted as our<br />

recommendations. Referring to the particular case they should be completed or revised.<br />

EC waste code: 16 05 09<br />

Waste notation:<br />

13. 13.1. 13. 1. 1.2 1. Cont Contaminated Cont Contaminated<br />

aminated aminated packaging packaging packaging packaging<br />

discarded chemicals other than those mentioned in 16 05 06, 16 05 07<br />

or 16 05 08<br />

Recommendation: Contaminated packaging should be emptied as far as possible and after<br />

appropriate cleansing may be taken <strong>for</strong> reuse.<br />

Recommended cleansing agent:<br />

Packaging that cannot be cleaned:<br />

Water.<br />

EC waste code: 15 01 06<br />

Waste notation: mixed packaging<br />

14. 14. Transport Transport in<strong>for</strong>mation<br />

in<strong>for</strong>mation<br />

14.1 14.1 UN UN UN UN number number number number<br />

No dangerous good in accordance with the UN Model Regulations (ADR/RID/ADN/IMDG/ICAO).<br />

14.2 14.2 UN UN UN UN proper proper proper proper shipping shipping shipping shipping name name name name<br />

Not relevant.<br />

14.3 14.3 Transport Transport Transport Transport hazard hazard hazard hazard class(es) class(es) class(es) class(es)<br />

Not relevant.<br />

14.4 14.4 Packing Packing Packing Packing group group group group<br />

Not relevant.<br />

14.5 Environmental Environmental Environmental Environmental hazards hazards hazards hazards<br />

Not relevant.<br />

14.6 14.6 Special Special Special Special precautions precautions precautions precautions <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> user user user user<br />

Not relevant.<br />

14.7 14.7 Transport Transport Transport Transport in in in in bulk bulk bulk bulk according according according according to to to to Annex Annex Annex Annex II II II II of of of of MARPOL MARPOL MARPOL MARPOL 73/78 73/78 73/78 73/78 and and and and the the the the IBC IBC IBC IBC Code Code Code Code<br />

Not relevant.


Safety Safety data data sheet sheet in in accordance accordance accordance with with Regulation Regulation (EC) (EC) No No 1907/200 1907/2006 1907/200<br />

Page 7 of 8<br />

Trade name: <strong>Mops</strong> <strong>Mops</strong>-<strong>Tris</strong> <strong>Mops</strong><br />

<strong>Tris</strong> <strong>Tris</strong>-SDS <strong>Tris</strong> SDS Running Buffer <strong>for</strong> Va VarioGel Va<br />

rioGel ® (20x (20x Concentrate)<br />

Concentrate)<br />

Company/Undertaking: <strong>anamed</strong> <strong>Elektrophorese</strong> <strong>Elektrophorese</strong> GmbH<br />

Ringstraße Ringstraße 44,<br />

4 , DD-64<br />

D 64 6440<br />

401 40 1 Gross Gross-Bieberau<br />

Gross<br />

Bieberau<br />

Telephone: int+49 int+49-(0)61<br />

int+49<br />

(0)61 (0)6162<br />

62-809840<br />

62 809840 Revision: 30.04.2011<br />

Product number: anam0031<br />

15. Regulatory inf in<strong>for</strong>mation<br />

inf<br />

ormation<br />

15.1 15.1 Safety, Safety, Safety, Safety, health health health health and and and and environmental environmental environmental environmental regulations/legislation regulations/legislation regulations/legislation regulations/legislation specific specific specific specific <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> the the the the substance substance substance substance or or or or mixture mixture mixture mixture<br />

15.1.1 15.1.1 15.1.1 In<strong>for</strong>mation In<strong>for</strong>mation In<strong>for</strong>mation In<strong>for</strong>mation regarding regarding regarding regarding relevant relevant relevant relevant Community Community Community Community provisions provisions provisions provisions<br />

None.<br />

15.1.2 15.1.2 In<strong>for</strong>mation In<strong>for</strong>mation In<strong>for</strong>mation In<strong>for</strong>mation regarding regarding regarding regarding national national national national laws/national laws/national<br />

laws/national<br />

laws/national measures measures measures measures that that that that may may may may be be be be relevant relevant relevant relevant (<strong>for</strong> (<strong>for</strong> (<strong>for</strong> (<strong>for</strong> Germany Germany Germany Germany only) only) only) only)<br />

Restriction of occupation: Not relevant<br />

Major-accident Regulation: Not relevant<br />

Fire and explosion hazards: Not relevant<br />

Regulation on clean air (TA Luft): Not relevant<br />

Water hazard class: WGK 2 – hazardous to water<br />

(calculation according to KBwS) 4<br />

German Ordinance on Hazardous Substances<br />

The Federal State Enactment <strong>for</strong> Facilities to Handle Water<br />

Endangering Substances (German VAwS–Anlagen-Verordnung)<br />

has to be observed.<br />

(in accordance with EC-Directive 98/24/EC): Article 6 must be observed<br />

Articles 7, 8 and 14 must be observed as required<br />

Technical Rules <strong>for</strong> Hazardous Substances1 : TRGS 400, 500, 510<br />

Rules of the employers´ liability insurance association2 : BGR 189, 190, 192, 195<br />

15. 15.2 15.<br />

Chemical Chemical Chemical Chemical Safety Safety Safety Safety Assessment<br />

Assessm Assessm Assessment<br />

ent ent<br />

No Chemical Safety Assessment has been carried out <strong>for</strong> a substance in the product.<br />

16. Other in<strong>for</strong>mation<br />

16.1 16.1 Keeping Keeping Keeping Keeping (restrictions) (restrictions)<br />

(restrictions)<br />

(restrictions)<br />

Not relevant<br />

Supply Supply Supply Supply<br />

University (college, academy), industry consumer<br />

16.2 16.2 Full Full Full Full text text text text of of of of the the the the R RR<br />

R phrases phrases phrases phrases referred referred referred referred to to to to under unde unde under<br />

r r point point point point 3.2.2 3.2.2 3.2.2 3.2.2 of of of of the the the the Safety Safety Safety Safety Data Data Data Data Sheet Sheet Sheet Sheet<br />

R11 Highly flammable.<br />

R21/22 Harmful in contact with skin and if swallowed.<br />

R36/38 Irritating to eyes and skin.<br />

R36/37/38 Irritating to eyes, respiratory system and skin.<br />

16.3 16.3 Full Full Full Full text text text text of of of of the the the the hazard hazard hazard hazard statements statements statements statements referred rr<br />

referred<br />

eferred eferred to to to to under under under under point point point point 3.2.3 3.2.3 3.2.3 3.2.3 of of of of the the the the Safety Safety Safety Safety Data Data Data Data Sheet Sheet Sheet Sheet<br />

H228 Flammable solid.<br />

H302 Harmful if swallowed.<br />

H311 Toxic in contact with skin.<br />

H315 Causes skin irritation.<br />

H319 Causes serious eye irritation.<br />

H335 May cause respiratory irritation.<br />

16.4 16.4 CCCClassification lassification lassification lassification and and and and labelling labelling labelling labelling in in in in accordance accordance accordance accordance with with with with Regulation Regulation Regulation Regulation (EC) (EC) (EC) (EC) No No No No 1272/2008<br />

1272/2008<br />

1272/2008<br />

1272/2008<br />

16.4.1 16.4.1 Classification<br />

Classification<br />

Classification<br />

Classification<br />

The product does not meet the criteria <strong>for</strong> a classification as hazardous in accordance with the current version of<br />

Regulation (EC) No 1272/2008.<br />

16.4.2 16.4.2 LLLLabelling abelling abelling abelling<br />

Hazard pictogram(s): No pictogram<br />

Signal word(s): No signal word<br />

Product identifier: Not required<br />

Hazard statements: Not required<br />

Precuationary statements: Not required<br />

Supplemental label <strong>for</strong> certain mixtures:<br />

According to Annex II Part 2 section 2.10 of the Regulation (EC) No 1272/2008 the label on the packaging of mixtures<br />

mixtures<br />

not intended <strong>for</strong> the the general public shall bear the statement:<br />

EUH 210 – “Safety data sheet available on request”.<br />

Remark: The classification and labelling of the product in accordance with Regulation (EC) No 1272/2008<br />

has been provided with the assistance of the the GHS-converter5 of the employers´ liability insurance<br />

association.


Safety Safety data data sheet sheet in in accordance accordance accordance with with Regulation Regulation (EC) (EC) No No 1907/200 1907/2006 1907/200<br />

Page 8 of 8<br />

Trade name: <strong>Mops</strong> <strong>Mops</strong>-<strong>Tris</strong> <strong>Mops</strong><br />

<strong>Tris</strong> <strong>Tris</strong>-SDS <strong>Tris</strong> SDS Running Buffer <strong>for</strong> Va VarioGel Va<br />

rioGel ® (20x (20x Concentrate)<br />

Concentrate)<br />

Company/Undertaking: <strong>anamed</strong> <strong>Elektrophorese</strong> <strong>Elektrophorese</strong> GmbH<br />

Ringstraße Ringstraße 44,<br />

4 , DD-64<br />

D 64 6440<br />

401 40 1 Gross Gross-Bieberau<br />

Gross<br />

Bieberau<br />

Telephone: int+49 int+49-(0)61<br />

int+49<br />

(0)61 (0)6162<br />

62-809840<br />

62 809840 Revision: 30.04.2011<br />

Product number: anam0031<br />

16. 16.5 16.<br />

Key Key Key Key to to to to abbreviations abbreviations abbreviations abbreviations and and and and acronyms acronyms acronyms acronyms used used used used in in in in the the the the safety safety safety safety da data da data<br />

ta ta sheet sheet sheet sheet<br />

ADN: Accord européen relatif au transport international des marchandises dangereuses par voie de<br />

navigation intérieure<br />

ADR: Accord européen relatif au transport international des marchandises dangereuses par route<br />

AOX: adsorbable organically bound halogens<br />

ICAO: International Civil Aviation Organisation.<br />

IMDG-Code: International Maritime Dangerous Goods-Code<br />

IUCLID: International Uni<strong>for</strong>m ChemicaL In<strong>for</strong>mation Database<br />

KBwS: Commission <strong>for</strong> the Evaluation of substances hazardous to waters (Kommission Bewertung<br />

wassergefährdende Stoffe)<br />

LGK: Lagerklasse (storage class)<br />

OECD: Organisation <strong>for</strong> Economic Co-operation and Development<br />

PBT: persistent, bioaccumulative and toxic<br />

RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer<br />

RTECS: Registry of Toxic Effects of Chemical Substances<br />

TRGS: Technische Regeln für Gefahrstoffe (Technical Rules <strong>for</strong> Hazardous Substances)<br />

vPvB: very persistent and very bioaccumulative<br />

16. 16.6 16.<br />

Literature Literature Literature Literature references references references references and and and and sources sources sources sources <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> data data data data<br />

1 http://www.baua.de<br />

2 http://www.arbeitssicherheit.de<br />

3 http://logkow.cisti.nrc.ca<br />

4 http://www.umweltbundesamt.de<br />

5 http://www.gischem.de/ghs/index.htm<br />

16. 16.7 16.<br />

Method Method Method Method used used used used <strong>for</strong> <strong>for</strong> <strong>for</strong> <strong>for</strong> the the the the classification classification classification classification of of of of the the the the mixture mixture mixture mixture<br />

The product does not meet the criteria <strong>for</strong> a classification as hazardous in accordance with the current versions<br />

of Directive 1999/45/EC and Regulation (EC) No 1272/2008.<br />

16.8 16.8 Changes Changes Changes Changes which which which which have have have have been been been been made made made made to to to to the the the the previous previous previous previous version version version version of of of of the the the the safety safety safety safety data data data data sheet sheet sheet sheet<br />

Revised Sections: due to adaptation to Annex I of the Regulation (EU) No 453/2010 (amendment of Annex II<br />

of Regulation (EC) No 1907/2006), this safety data sheet has been completely revised.<br />

The The above above in<strong>for</strong>mation in<strong>for</strong>mation describes describes exclusively exclusively the the safety safety requirements requirements of of the the product product and and is is based based on on our<br />

our<br />

present present-day present<br />

day kn knowledge. kn<br />

owledge. The in<strong>for</strong>mation is intended to give you advice advice about the safe handling of the product<br />

named named in in this this safety safety data data sheet, sheet, <strong>for</strong> <strong>for</strong> storage, storage, processing, processing, transport transport and and disposal. disposal. The The in<strong>for</strong>mation in<strong>for</strong>mation cannot cannot be<br />

be<br />

transferred to other products. In the the case of mixi mixing mixi<br />

ng the product with other products or in the case of<br />

processing, processing, the the in<strong>for</strong>mation in<strong>for</strong>mation on on this this safety safety data data sheet sheet is is not not necessarily necessarily valid valid <strong>for</strong> <strong>for</strong> the the new new made made-up made up material.<br />

material.<br />

Compiled by: Dr. Dr. Michael Michael Urban Urban<br />

Urban<br />

Fachberatung Fachberatung Fachberatung Gefahrstoff Gefahrstoff Gefahrg Gefahrgut Gefahrg ut<br />

Vogelbeerweg 3 D-26180 Rastede-Ipwege / Germany<br />

Tel.: int+49-(0)4402-695620 Fax: int+49-(0)4402-695621

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