Honc: Late recurrence of breast CA
Honc: Late recurrence of breast CA
Honc: Late recurrence of breast CA
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Neurotransmitters <strong>of</strong> clinical<br />
significance<br />
• Dopamine<br />
▫ D-2 antagonists<br />
▫ Metoclopramide, Prochlorperazine (Compazine)<br />
• Serotonin (5-HT)<br />
▫ Selective antagonists 5-HT3 receptor<br />
▫ Ondansetron (Z<strong>of</strong>ran), palonosetron (Aloxi)<br />
▫ Side effect: constipation, mild HA,<br />
• Substance P<br />
▫ Neurokinin-1-receptor antagonists<br />
▫ Aprepitant (Emend)<br />
• Endocannabinoids<br />
▫ Dronabinol and nabilone<br />
▫ Side effects: postural hypotension, dysphoria<br />
23