The Tell-Tale Stain
The Tell-Tale Stain
The Tell-Tale Stain
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New Mycobacterium species from 2 patients who died of diffuse<br />
lepromatous leprosy (DLL).<br />
DNA extraction from heavily infected freshly frozen liver tissue or<br />
paraffin-embedded skin tissue<br />
Six genes of the organism were sequenced.<br />
Significant genetic differences with M. leprae were found, including a<br />
2.1% divergence of the 16S ribosomal RNA (rRNA) gene,<br />
<strong>The</strong> unique clinicopathologic features of DLL led them to propose<br />
Mycobacterium lepromatosis sp nov.