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Carbon Monoxide Poisoning

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Delayed Neuropsychiatric Syndrome<br />

Delayed onset of neurologic symptoms after apparent<br />

recovery from acute CO intoxication<br />

Occurs 3-240 days (mean 20) in up to 50% of patients<br />

The development of DNS correlates poorly with COHb levels<br />

Symptoms: cognitive and personality changes, parkinsonism,<br />

dementia, psychosis, movement disorders<br />

Imaging will often show abnormalities within the globus<br />

pallidus and the deep white matter<br />

Recovery occurs in 50-75% of affected persons within one<br />

year

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