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March is Colorectal Cancer Awareness Month - Surgery

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New Clinical Trials<br />

J. Wesley Alexander, M.D., Div<strong>is</strong>ion of Transplantation:<br />

NIH-funded study at University Hospital and Chr<strong>is</strong>t Hospital: “A<br />

randomized trial of immunomodulating diets with arginine and<br />

omega-3 fatty acids in renal transplant recipients.” Th<strong>is</strong> study will<br />

evaluate the plasma and blood cell membrane absorption levels of<br />

amino acids and fatty acids in renal transplant patients receiving<br />

special transplant dietary supplements and will determine potential<br />

beneficial effects of decreased rejection ep<strong>is</strong>odes, decreased incidence<br />

of acute rejection, improved long-term allograft survival,<br />

reduced cardiac and vascular complications, reduced infectious<br />

complications, and improved quality of life.<br />

Internally funded study at University Hospital and Chr<strong>is</strong>t Hospital:<br />

“A pilot study of relationships of gastrointestinal hormones and<br />

appetite following gastric bypass.” Th<strong>is</strong> study will measure hormones<br />

which may be associated with loss of appetite following<br />

gastrointestinal bypass. Changes in the hormones after the procedure<br />

will be correlated with changes in appetite, the amount of<br />

weight loss and technical features of the operation, such as the size<br />

of the remaining gastric pouch and the lengths of the intestinal<br />

limbs that are a normal part of the operation.<br />

NIH-funded grant for the development of new technologies for<br />

studying the mechan<strong>is</strong>ms of graft acceptance or dysfunction following<br />

renal transplantation. The study, approved by the IRBs at<br />

University Hospital and Chr<strong>is</strong>t Hospital, <strong>is</strong> currently underway.<br />

For further information, please call (513)-558-6006.<br />

Recent Publications<br />

Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV. Modulation<br />

of endotoxin-induced endothelial activity by microtubule depolymerization.<br />

J Trauma 54:104-112, 2003.<br />

Giglia JS, J Ollerenshaw, P Dawson, K Black, WM Abbott.<br />

Cryopreservation prevents arterial allograft dilation. Ann Vasc<br />

Surg 16:762-767, 2002.<br />

Johannigman JA, Miller SL, Dav<strong>is</strong> BR, Dav<strong>is</strong> K, Campbell RS,<br />

Branson RD. Influence of low tidal volumes on gas exchange in<br />

acute respiratory d<strong>is</strong>tress syndrome and the role of recruitment<br />

maneuvers. J Trauma 54:320-325, 2003.<br />

Kitzmiller J. Non-invasive skin measurements after CO 2 and<br />

Erbium laser resurfacing. Aesthetic <strong>Surgery</strong> Journal 23:20-27,<br />

2003.<br />

Song JC, Rangachari PK, Matthews JB. Opposing effects of PKCalpha<br />

and PKC-epsilon on basolateral membrane dynamics in<br />

intestinal epithelia. Am J Physiol (Cell) 283(5):C1548-C1556,<br />

2002.<br />

Yoo J, Nichols A, Song JC, Mammen J, Calvo I, Worrell R,<br />

Cuppoletti J, Matlin K, Matthews JB. Bryostatin-1 attenuates TNFinduced<br />

epithelial barrier dysfunction: Role of novel PKC<br />

<strong>is</strong>ozymes. Am J Physiol (GI/Liver), Dec. 27, 2002.<br />

V<strong>is</strong>iting Professors<br />

Dr. Jeffrey L. Ponsky to V<strong>is</strong>it as John<br />

and Elizabeth McDonough V<strong>is</strong>iting<br />

Professor on April 8-9<br />

The Section of General <strong>Surgery</strong> will<br />

sponsor a v<strong>is</strong>it by Jeffrey L. Ponsky,<br />

M.D., Professor of <strong>Surgery</strong> and the<br />

Director of Endoscopic <strong>Surgery</strong> at<br />

The Cleveland Clinic Foundation.<br />

Dr. Ponsky will speak at Surgical<br />

Grand Rounds on Wednesday, April<br />

9, on “Therapeutic Pancreatico-<br />

Biliary Endoscopy: A Surgical Viewpoint.”<br />

At the Cincinnati Surgical<br />

Society that evening, Dr. Ponsky will<br />

speak on “New Horizons in Surgical<br />

Endoscopy.”<br />

Jeffrey L. Ponsky, M.D.<br />

******<br />

Dr. Gerald Buckberg to Lecture as<br />

V<strong>is</strong>iting Professor on May 13-14<br />

In honor of John B. Flege Jr., M.D.,<br />

Professor of <strong>Surgery</strong>, and establ<strong>is</strong>hment<br />

of the Flege Chair in <strong>Surgery</strong>,<br />

the Section of Cardiothoracic <strong>Surgery</strong><br />

will host Gerald D. Buckberg, M.D.,<br />

Professor of <strong>Surgery</strong>, Div<strong>is</strong>ion of<br />

Thoracic and Cardiovascular <strong>Surgery</strong>,<br />

at UCLA. Dr. Buckberg's v<strong>is</strong>it will<br />

include teaching activities as well as<br />

two lectures: “The Helix and the<br />

Heart” at Surgical Grand Rounds and<br />

“New Geometric Surgical Approaches<br />

Gerald D. Buckberg, M.D.<br />

to Congestive Heart Failure” at the<br />

Cincinnati Surgical Society.<br />

Upcoming Guest Speakers:<br />

May 21, 2003 - Frame Lectureship (Trauma/Critical Care): Rao<br />

R. Ivatury, M.D., Professor of <strong>Surgery</strong>, Medical College of<br />

Virginia - “Towards Optimal Resuscitation After Trauma”<br />

June 4, 2003 - Barrows V<strong>is</strong>iting Professor (Surgical Oncology):<br />

Douglas Evans, M.D., Professor of Surgical Oncology, MD<br />

Anderson <strong>Cancer</strong> Center - Topic to be announced<br />

Area physicians are invited to attend these lectures. Please contact<br />

Gilda Young at 513-558-4206 for further information.<br />

******

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