in-vitro and molecular studies on the resistance of p - Covenant ...

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DEDICATION This Ph.D work is dedicated to The Almighty God, The giver of all knowledge <strong>and</strong> wisdom. iv
ACKNOWLEDGEMENTS ‘Except the Lord builds a house, the builders labour <strong>in</strong> va<strong>in</strong>’. I return all thanks to the Almighty God for his mercies, faithfulness, grace, favour <strong>and</strong> <strong>in</strong>spiration that I enjoyed dur<strong>in</strong>g the course of this Ph.D programme. To him alone is all glory for a successful completion. I profoundly acknowledge the Chancellor of Covenant University for his spiritual motivation <strong>and</strong> for provid<strong>in</strong>g such an enabl<strong>in</strong>g environment from which I have benefited. I wish to express my profound gratitude to the management of Covenant University under the leadership of Prof. (Mrs) Aize Obayan for the support, advice <strong>and</strong> encouragement while the programme lasted. My s<strong>in</strong>cere appreciation goes to my chief supervisor, Professor A.O. Adeyeba for his awesome contributions, fatherly advice, thorough supervision <strong>and</strong> mentorship roles while on the research programme. I am privileged to have studied under his tutelage, most especially I want to appreciate him for h<strong>and</strong><strong>in</strong>g me over to Dr. Olusola Ojurongbe to take on the supervision when he was <strong>in</strong>disposed. I pray God for the speedy restoration of his health. I am s<strong>in</strong>cerely grateful to my supervisor, Dr. Ojurongbe for his useful advice, guided supervision <strong>and</strong> timely encouragement. He came to my rescue when I would have been str<strong>and</strong>ed. I am most grateful. I also want to appreciate Prof. Louis O. Egwari <strong>and</strong> Dr. O.E. Fagade who jo<strong>in</strong>tly co-supervised this work. I am <strong>in</strong>debted to their thoroughness <strong>and</strong> eagle eyes that shaped this work. I profoundly appreciate the Third World Organisation for Women <strong>in</strong> Science-Third World Academy of Science (TWOWS-TWAS) for grant<strong>in</strong>g me the 2007 TWAS-TWOWS postgraduate research fellowship award which was utilized at the National Institute of Malaria Research, New (NIMR) Delhi, India. I greatly appreciate the <strong>in</strong>tellectual, material <strong>and</strong> f<strong>in</strong>ancial contributions of TWOWS, TWAS <strong>and</strong> NIMR. I will forever be grateful for the <strong>in</strong>valuable contributions of Dr. Neena Valecha, my host supervisor <strong>in</strong> India, Dr. Anup Anvikar, the Head of malaria parasite bank <strong>and</strong> cell culture laboratories, Dr. Ruchi S<strong>in</strong>gh of Molecular biology laboratories <strong>and</strong> Dr. Pillai for useful advice care <strong>and</strong>. My special appreciation also goes to all the staff <strong>and</strong> students of Microscopy laboratories, Parasite bank <strong>and</strong> <strong>molecular</strong> biology laboratories for all their love <strong>and</strong> v
Page 1 and 2: IN-VITRO AND MOLECULAR STUDIES ON T
Page 3: DECLARATION We declare that this th
Page 7 and 8: CONTENT Title Page Title Page……
Page 9 and 10: 3.5 Sample Collection…………
Page 11 and 12: ABBREVIATIONS ADP Adenosin<
Page 13 and 14: LIST OF TABLES Table Title Page Tab
Page 15 and 16: ABSTRACT The widespread of drug res

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