Is there a place for conservative management of CIN2? - National ...

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A pragmatic and simplistic view! CIN1 •An acute viral infection •Likely to regress •Conservative management recommended CIN2 CIN 3 •Associated with persistent HPV infection. •Unlikely to regress •Associated with significant risk of invasion •Treatment recommended
My opinion • Many young women with CIN2/ HSIL will undergo spontaneous regression. • Political risk to non screening in under 25s (7 cases 2010/11). • Vaccination rates currently too low to have major impact • Currently conservative management of CIN2 cannot be considered standard treatment. • Those wishing to offer conservative management should enrol patients in Princess.
Page 1 and 2: Peter Sykes NCSP Colposcopy Symposi
Page 3: Aims /outcome measures Study Aims
Page 7 and 8: • Peter Sykes, Bryony Simcock •
Page 9 and 10: How did we get here • Known regre
Page 11 and 12: Adverse pregnancy outcomes associat
Page 13 and 14: Very low risk of cancer under the a
Page 15 and 16: Regression of CIN2 authour date Reg
Page 17 and 18: findings • 452 women under 25 wit
Page 19 and 20: Conservative management greater tha
Page 21 and 22: Currently HPV status most predictiv
Page 23: Biopsy correlates poorly with loop

Is there a place for conservative management of CIN2? - National ...

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