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Prescribing Eyeglass Correction for Astigmatism in Infancy and Early ...

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190 Harvey et al<br />

FIG 1. Survey sent to 2004 North American AAPOS Members.<br />

METHODS<br />

Names <strong>and</strong> addresses of the 700 2004 North American<br />

AAPOS members were obta<strong>in</strong>ed from the AAPOS web<br />

site. The survey shown <strong>in</strong> Figure 1, along with a cover<br />

letter, was mailed to each member <strong>in</strong> March 2004. Approximately<br />

1 month later, a second letter <strong>and</strong> survey were<br />

sent to members who did not respond to the first mail<strong>in</strong>g.<br />

RESULTS<br />

A total of 412/700 surveys (59%) was returned. For some<br />

age groups, some pediatric ophthalmologists <strong>in</strong>dicated<br />

“none” or “would not prescribe” <strong>for</strong> amount of astigmatism<br />

needed to prescribe eyeglasses. We <strong>in</strong>terpreted this as<br />

<strong>in</strong>dicat<strong>in</strong>g that, <strong>for</strong> that age group, they would not prescribe<br />

<strong>for</strong> any amount of astigmatism present. A summary<br />

of the percentage of responders who would not prescribe<br />

<strong>for</strong> each age group is provided <strong>in</strong> Table 1.<br />

Table 2 presents a summary of responses, along with<br />

results from the Miller <strong>and</strong> Harvey survey 16 <strong>and</strong> the AAO<br />

guidel<strong>in</strong>es. 17 Results are presented <strong>in</strong> percentiles rather<br />

than means to m<strong>in</strong>imize the effects of extreme values <strong>in</strong><br />

skew<strong>in</strong>g the distribution <strong>and</strong> to allow <strong>for</strong> <strong>in</strong>clusion of all<br />

responses, <strong>in</strong>clud<strong>in</strong>g the “would not prescribe” responses.<br />

The “would not prescribe” responses were assigned a value<br />

beyond the upper limit of the distribution of responses so<br />

that they would be represented at the high end of the<br />

distribution. Percentiles were also calculated exclud<strong>in</strong>g<br />

“would not prescribe” responses. This analysis resulted <strong>in</strong><br />

changes to percentiles primarily <strong>for</strong> the 0 to 6-monthold<br />

age group (percentiles that changed are shown <strong>in</strong><br />

parentheses <strong>in</strong> Table 2).<br />

Paired Wilcoxon signed rank tests compar<strong>in</strong>g responses<br />

<strong>for</strong> bilateral astigmatism across adjacent age groups<br />

yielded significant differences on all comparisons both<br />

when “would not prescribe” responses were <strong>in</strong>cluded <strong>and</strong><br />

when they were excluded (all P values 0.001). All comparisons<br />

of responses <strong>for</strong> astigmatic anisometropia across<br />

adjacent age groups were also significant both when<br />

“would not prescribe” responses were <strong>in</strong>cluded <strong>and</strong> when<br />

they were excluded (all P values 0.001).<br />

DISCUSSION<br />

Journal of AAPOS<br />

Volume 9 Number 2 April 2005<br />

The results of the present study suggest that the 2-year age<br />

group<strong>in</strong>g used <strong>in</strong> the previous survey conducted by Miller<br />

<strong>and</strong> Harvey 16 was too large to provide an accurate picture of<br />

prescrib<strong>in</strong>g practices of pediatric ophthalmologists <strong>for</strong> <strong>in</strong>fants<br />

<strong>and</strong> children less than 2 years of age. As shown <strong>in</strong> Tables 1<br />

<strong>and</strong> 2, when pediatric ophthalmologists were asked to break<br />

down their responses <strong>for</strong> children less than 2 years of age <strong>in</strong>to<br />

three age categories (0 to 6 months, 6 to 12 months, <strong>and</strong><br />

12 to 24 months), there were significant differences across<br />

age categories both <strong>in</strong> whether spectacles would be prescribed<br />

<strong>and</strong> <strong>in</strong> the level of astigmatism at which spectacles would be<br />

prescribed.<br />

The AAO prescrib<strong>in</strong>g guidel<strong>in</strong>es 17 use 1-year age group<strong>in</strong>gs.<br />

As shown <strong>in</strong> Table 2, the AAO guidel<strong>in</strong>es are similar to<br />

the 50th or 75th percentile data <strong>for</strong> prescrib<strong>in</strong>g at all ages<br />

except 0 to 6 months. For this youngest age, AAO guidel<strong>in</strong>es<br />

were more similar to the 25th percentile data than to the<br />

50th or 75th percentile data. This suggests that the general<br />

category of 0 to 1 year used <strong>in</strong> the AAO guidel<strong>in</strong>es may also<br />

be too broad, as prescrib<strong>in</strong>g recommendations based on the<br />

present survey yielded different results <strong>for</strong> 0- to 6- <strong>and</strong> 6- to<br />

12-month olds, with higher prescrib<strong>in</strong>g thresholds <strong>for</strong> the<br />

younger <strong>in</strong>fants.<br />

Similar to the AAO prescrib<strong>in</strong>g guidel<strong>in</strong>es, 17 prescrib<strong>in</strong>g<br />

guidel<strong>in</strong>es used <strong>in</strong> the multicenter CRYO-ROP study 18,19<br />

were based on the consensus of a small number of ophthalmologists<br />

<strong>and</strong>, similar to the AAO guidel<strong>in</strong>es, the CRYO-<br />

ROP guidel<strong>in</strong>es recommend eyeglass correction at levels of<br />

astigmatism <strong>and</strong> astigmatic anisometropia similar to the 50th<br />

<strong>and</strong> 75th percentile data from the present survey.<br />

F<strong>in</strong>ally, it is important to note that prescrib<strong>in</strong>g practices<br />

<strong>for</strong> astigmatism <strong>in</strong> <strong>in</strong>fants <strong>and</strong> young children are likely to<br />

depend on other factors <strong>in</strong> addition to the magnitude of<br />

astigmatism or astigmatic anisometropia. For example, it is<br />

likely that spectacle-prescrib<strong>in</strong>g practices take <strong>in</strong>to account<br />

the presence or absence of amblyopia <strong>and</strong> strabismus,<br />

as well as the axis of the astigmatism. Previous research<br />

has <strong>in</strong>dicated that oblique axis astigmatism presents<br />

a greater risk factor <strong>for</strong> development of amblyopia than<br />

with-the-rule or aga<strong>in</strong>st-the-rule astigmatism. 20,21 The<br />

survey results do not reflect the extent to which these<br />

other factors <strong>in</strong>fluence prescrib<strong>in</strong>g practices.<br />

TABLE 1. Percentage of “Would not Prescribe” responses, based on<br />

survey results from 412 AAPOS members<br />

Condition<br />

Age Range<br />

(months) N (%)<br />

Bilateral astigmatism 0 to 6 96 (23)<br />

6to12 30 (7)<br />

12 to 24 6 (1)<br />

24 to 36 1 (0.2)<br />

Astigmatic anisometropia 0 to 6 83 (20)<br />

6to12 22 (5)<br />

12 to 24 2 (1)<br />

24 to 36 1 (0.2)

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