Bioisosteres & Validation
Bioisosteres & Validation
Bioisosteres & Validation
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Simple validation<br />
percent of total<br />
80<br />
70<br />
60<br />
50<br />
40<br />
30<br />
20<br />
10<br />
0<br />
Conservative <strong>Bioisosteres</strong><br />
Color Similarity (N=42)<br />
1.8<br />
similarity (0-2)<br />
Random<br />
Known<br />
CUP VIII, Santa Fe, Feb 2007
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