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AN INTRODUCTION TO RECOMBINATION AND LINKAGE ANALYSIS

AN INTRODUCTION TO RECOMBINATION AND LINKAGE ANALYSIS

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Derivation of Mather’s Formula<br />

Under NCI assumption, if there are N crossovers in the chiasma<br />

process on an interval, with N>0, the the chance of having i crossovers<br />

on a given chromatid is<br />

Recombination will occur in the interval If the chromatid is involved in<br />

an odd number of crossovers

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