GFS Organics Modern Acetylene Chemistry for ... - ThomasNet
GFS Organics Modern Acetylene Chemistry for ... - ThomasNet
GFS Organics Modern Acetylene Chemistry for ... - ThomasNet
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and phenylacetylene has<br />
become a base chemistry<br />
plat<strong>for</strong>m <strong>for</strong> several on-going<br />
projects as well as new<br />
development projects and<br />
alternative chemistry routes<br />
<strong>for</strong> existing products.<br />
Alkynes have become core<br />
building blocks <strong>for</strong> several<br />
other functionalized products<br />
such as our specialty olefins,<br />
diactylenic intermediates and<br />
specialty heterocycles, to<br />
name a few. We estimate that<br />
alkyne chemistry is responsible<br />
<strong>for</strong> approximately 15%<br />
of all R&D work today. The<br />
growing number of literature<br />
references that use acetylenic<br />
intermediates in organic<br />
synthesis demonstrates the<br />
impact this chemical family<br />
continues to have on the<br />
research community from<br />
“Click <strong>Chemistry</strong>” ® used to<br />
assemble complex heteroaromatics<br />
and other heterocycles<br />
to the construction<br />
of chromophores.<br />
4<br />
ALKYNES<br />
R C C R<br />
R C<br />
O<br />
O H<br />
R C OH<br />
R CC n<br />
R C<br />
C C m X<br />
O<br />
H<br />
R C C H<br />
R C C(O)R’<br />
R C<br />
R C C C n X<br />
O<br />
O R’<br />
R C C R’<br />
R C C<br />
OH