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GFS Organics Modern Acetylene Chemistry for ... - ThomasNet

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and phenylacetylene has<br />

become a base chemistry<br />

plat<strong>for</strong>m <strong>for</strong> several on-going<br />

projects as well as new<br />

development projects and<br />

alternative chemistry routes<br />

<strong>for</strong> existing products.<br />

Alkynes have become core<br />

building blocks <strong>for</strong> several<br />

other functionalized products<br />

such as our specialty olefins,<br />

diactylenic intermediates and<br />

specialty heterocycles, to<br />

name a few. We estimate that<br />

alkyne chemistry is responsible<br />

<strong>for</strong> approximately 15%<br />

of all R&D work today. The<br />

growing number of literature<br />

references that use acetylenic<br />

intermediates in organic<br />

synthesis demonstrates the<br />

impact this chemical family<br />

continues to have on the<br />

research community from<br />

“Click <strong>Chemistry</strong>” ® used to<br />

assemble complex heteroaromatics<br />

and other heterocycles<br />

to the construction<br />

of chromophores.<br />

4<br />

ALKYNES<br />

R C C R<br />

R C<br />

O<br />

O H<br />

R C OH<br />

R CC n<br />

R C<br />

C C m X<br />

O<br />

H<br />

R C C H<br />

R C C(O)R’<br />

R C<br />

R C C C n X<br />

O<br />

O R’<br />

R C C R’<br />

R C C<br />

OH

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