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Statistical Event-History Problems for Differential Diagnosis in ...

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<strong>Event</strong>-history <strong>Event</strong> history data on hypertension:<br />

hypertension:<br />

<strong>Differential</strong> diagnosis of apudoma? apudoma<br />

Primary HPT (90% 90%)<br />

Bilateral renal parenchymal disease<br />

(5%) %)<br />

Chronic glomerulonephritis<br />

Interstitial nephritis<br />

Polycystic disease<br />

Diabetic nephropathy<br />

Systematic lupus erythematosus<br />

Amyloidosis<br />

Multiple myeloma<br />

Scleroderma<br />

Wegener’s<br />

Wegener s granulomatosis<br />

Goodpasture’s Goodpasture disease<br />

Periarteritis nodosa<br />

Takayasu’s Takayasu arteritis<br />

Vasculitis<br />

Balkan nephritis<br />

Congenital renal disease<br />

Italics = Have no catecholam<strong>in</strong>e and/or and or<br />

other metabolite excess<br />

Starred = May have paroxysmal HPT<br />

Red = Apudoma (am<strong>in</strong>e ( am<strong>in</strong>e precursor update<br />

and decarboxylation)<br />

decarboxylation)<br />

cells<br />

Other diastolic HPT causes (5% 5%) )<br />

Acute multiple sclerosis<br />

Fatal familial <strong>in</strong>somnia<br />

Sp<strong>in</strong>al cord lesion *<br />

Acute <strong>in</strong>termittent porphyria *<br />

Acute bulbar poliomyelitis *<br />

Baroreflex failure *<br />

Cush<strong>in</strong>g’s Cush<strong>in</strong>g s disease or syndrome<br />

Renal/ Renal/<br />

ren<strong>in</strong>-secret<strong>in</strong>g ren<strong>in</strong> secret<strong>in</strong>g tumor<br />

Acute coronary <strong>in</strong>sufficiency +/- +/<br />

myocardial <strong>in</strong>farct) <strong>in</strong>farct)<br />

*<br />

Hypersensitivity reactions *<br />

Hypothalamic tumor *<br />

Fibrosarcoma <strong>in</strong> pulmonary artery *<br />

Pheochromocytoma *<br />

Neuroblastoma */ Ganglioneuroma *<br />

Gastroenteropancreatic<br />

neuroendocr<strong>in</strong>e tumor *<br />

Intracranial-pressure<br />

Intracranial pressure-caus<strong>in</strong>g caus<strong>in</strong>g<br />

lesions *<br />

Guillian-Barre<br />

Guillian Barre syndrome *<br />

Hypoglycemia *<br />

Clonid<strong>in</strong>e withdrawal<br />

Mastocytosis

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