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A CLINICO.PATHOLOGICAL STUDY OF ANAL FISTULAE

A CLINICO.PATHOLOGICAL STUDY OF ANAL FISTULAE

A CLINICO.PATHOLOGICAL STUDY OF ANAL FISTULAE

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Anal Flstula ,<br />

Review of Literuture<br />

antiviral therapy benefits patients wrttr histotogically sonfirmed disease;<br />

and 4) in patients with persistent immune deficiency( for example, AIDS),<br />

virologic, histologic, and symptomatic relapse occurs after cessation of<br />

antiviral therapy.<br />

f<br />

A reasonable definition of cMV intestinal disease(as opposed to<br />

infection only) is an erosive or ulcerative process in the wall of the gut in<br />

which the presence of cMv is shown by routine histologic examination,<br />

culture, or antigen or DNA staining, in a person in whom other<br />

explanations for the lesion (s) have been excluded.<br />

#<br />

Fig. l0: Endoscopic gastric mucosal biopsy specimen from an AIDS<br />

patient with severe nausea, vomiting, and epigasric pain.showing tlpical<br />

cytomegalic cell shows a large, densely stained nucleus with<br />

intracytoplasmic inclusions (original maginfication x400).<br />

#<br />

f,<br />

React ivat ion and Re infection<br />

cytornegalovirus disease in the setting of immunodeficiency can be<br />

the result of either a primary cMv infection in a previously uninfected<br />

?8

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