JOHN E. KAPLAN, Ph.D. Business Address - Albany Medical Center

JOHN E. KAPLAN, Ph.D.
Business Address:
Center for Cardiovascular Sciences, Mail Code-8
Albany Medical College
47 New Scotland Avenue
Albany, New York 12208
Phone: (518)262-5543
Fax: (518)262-5689
E-Mail: kaplanj@mail.AMC.EDU
Date of Birth: December 4, 1950
Marital Status:
Married; two children
Social Security No:
EDUCATION:
1968-1972: University of Illinois, Urbana, IL; B.S. in Biology
1972-1973: Predoctoral Student, Department of Physiology, University of Illinois College of
Medicine, Chicago, IL
1973-1975: Predoctoral Student, Department of Physiology, Albany Medical College, Albany, NY;
1975-1977: NIH-NRSA Postdoctoral Research Fellow, Department of Physiology, Albany Medical
College, Albany, NY
1983-1984: Coursework - Institute of Administration & Management, Union College,
Schenectady, NY
POSITIONS HELD:
2008-Present:
2007-Present:
2006-Present:
2000-present:
2001-present:
Director of Graduate Studies, Alden March Bioethics Institute at Albany Medical College
Professor of Bioethics, Graduate College of Union University
Faculty, Alden March Bioethics Institute at Albany Medical College
Professor, Center for Cardiovascular Sciences, Albany Medical College
Member, Center for Medical Ethics, Education and Research, Albany Medical College
2002-2006: Professor of Bioethics, Joint Program AMC and Graduate College of Union University
1998-2000: Professor of Biochemistry & Molecular Biology, Albany Medical College
1997-2000: Member, Vascular Biology Research Group, Albany Medical College
1991-1998: Associate Dean for Graduate Studies, Albany Medical College
1990-present: Professor of Biomedical Sciences, State University of New York,
School of Public Health
1986-2000: Professor of Physiology & Cell Biology, Albany Medical College
1990-1991: Vice Chairman of Physiology & Cell Biology, Albany Medical College
1984-1990: Associate Professor of Biomedical Sciences, State University of New York,
School of Public Health

1980-1986: Associate Professor of Physiology, Albany Medical College
1977-1980: Assistant Professor of Physiology, Albany Medical College
1976-1977: Instructor in Physiology, Albany Medical College
HONORS, FELLOWSHIPS and SCHOLARSHIPS:
National Merit Letter of Commendation
Illinois State Scholarships (Honorary)
Edmond J. James Scholar (University of Illinois-Urbana)
Honors Day Recognition (University of Illinois-Urbana)
Predoctoral Fellowship (University of Illinois-Chicago)
Predoctoral Fellowship (Albany Medical College)
Trustee Scholarship (Albany Medical College)
National Research Science Awardee and Fellow
Recipient, Research Career Development Award, National Inst. General Medical Sciences
Scholar of Alexandrine and Alexander R. Sinsheimer Fund
Research Volunteer Award, American Heart Association, NYS Affiliate
Lifetime Achievement Award of Graduate Student Organization (Albany Medical College)
SOCIETY MEMBERSHIPS:
Sigma Xi (State University of New York at Albany chapter)
Society for Leukocyte Biology
American Heart Association (Northeastern New York Chapter & Thrombosis Council)
American Association for the Advancement of Science
American Physiological Society
Shock Society
New York Academy of Science
American Society of Cell Biology
America Association of Medical Colleges –
Group on Graduate Research Education and Training - (GREAT Group)
GREAT Group Planning Committee
Group on Institutional Planning
REVIEWER FOR:
Guest Referee: Journal of Leukocyte Biology
Journal of Laboratory and Clinical Medicine
Experimental and Molecular Pathology
Circulatory Shock
American Journal of Physiology
Analytical Biochemistry
Journal of Biological Chemistry
Federation Proceedings
Journal of the American Society of Veterinary Medicine
Microvascular Research
Journal of Clinical Investigation
Journal of Pharmacology and Experimental Therapeutics
Journal of Applied Physiology
Proceeding of the National Academy of Sciences
Thrombosis Research
American Journal of Respiratory and Critical Care Medicine
2

TEACHING EXPERIENCE:
Medical:
Lecture, laboratory & conference teaching - Medical Physiology and Integrated Curriculum, Albany
Medical College
Theme Leader – Endocrinology and Metabolism Theme, Integrated First Year Curriculum, Albany
Medical College
Comprehensive Care Case Studies-first and second year
Evidence Based Health Care-first and second year
Health Care and Society-first and second year
Learning to Teach, Teaching to Learn-fourth year
Undergraduate:
Laboratory Teaching - Physiology - Albany College of Pharmacy
Lecture, lab. & conference teaching - Systems Physiology - Rensselaer Polytechnic Institute
Graduate Course Instruction:
Albany Medical College:
Pathophysiology of the Reticuloendothelial System
Cardiovascular Response to Shock
Physiology of Plasma Proteins
Radioisotope Methology
Physiology of Blood Coagulation and Hemostasis (Course Director)
Cellular & Molecular Immunology
Cell Biology of Phagocytic Cells
Mammalian Physiology
Physiology for the Allied Health Sciences
Cellular and Molecular Basis of Disease
Molecular Basis of Integrin Function (Co-Course Director)
Discussions in Scientific Integrity (Course Director)
Introduction to Ethics (Course Director)
Fundamentals of Research Ethics (Course Director)
SUNYA School of Public Health Sciences:
Introduction to Biomedical Sciences
Responsible Conduct of Research (Course Director)
ADVISOR and MENTOR to:
Graduate Students:
Philip Snedeker, Ph.D. (1977-1982)
Dudley Moon, Ph.D. (1979-1983)
Paul Sherman, M.S. (1986-1989)
Brian Matayoshi, Ph.D. (1982-1989)
Abia Tloti, M.S. (1987-1989; Fulbright Fellow)
Catherine Venturini, Ph.D. (1987-1990)
Scott Blystone, Ph.D. (1987-1992)
Lisa Weston, M.S. (1989-1993)
Stan Penc (Ph.D. Program, 1990-1995)
Won Chung (M.D./M.S., 1992-1998)
Steven An (M.S. Program, 1993-1998)
Sofia Bhattacharya (M.S. Program, 1995-1997)
Danira Mayes (M.S. Program, 1995-2000)
Yasmeen Syed (M.S. Program, 1995-1999)
Advisor to multiple MS in Bioethics students, Alden March Bioethics Institute
M.D. with Distinction in Research: Vijay Nayak M.D., 1998-2000
Postdoctoral Fellows:
F. James Rourke, Ph.D. (NRSA Fellow, 1981-1983)
Elia Sahioun, M.D. (Middle Eastern Peace Fellow)
Raymond Ciaglowski, Ph.D. (NRSA Fellow, 1984)
Kenneth Burhop, Ph.D. (NRSA Fellow, 1984-1986)
3

Jonathan Shepard, Ph.D. (NRSA Fellow, 1985-1987)
Philip Paty, M.D. (NRSA Fellow, 1988-1990)
Multiple undergraduate and medical students
4

ADMINISTRATIVE RESPONSIBILITIES:
Albany Medical College:
DEPARTMENT OF PHYSIOLOGY AND CELL BIOLOGY
Chairman, Department of Physiology Graduate Studies Committee ................................ 1977-1985
Chairman, Department of Physiology Seminar Committee ............................................ 1978
Faculty Search Committee, Department of Physiology ................................................. 1979
Director, Shared Instrumentation Program Grant "Scintigraphic Evaluation of
Physiologic Events" .............................................................................................. 1980-1984
Vice Chair............................................................................................................. 1990-1991
Chair - Space Committee ........................................................................................ 1990
Search Coordinator - Faculty Recruitment .................................................................. 1996
MEDICAL COLLEGE
Secretary, Ad Hoc Committee of the Board of Trustees for Development
of a Research Practice Plan ................................................................................... 1980-1981
Member, Medical Admissions Committee .................................................................. 1980-1985,1999-
Member, Subcommittee on Essential Medical Knowledge-General Professional
Education of the Physician .................................................................................... 1983
Member, Minority Summer Fellowship Committee ....................................................... 1982
Member, Accreditation Task Force-Liaison Committee Medical
Education Accreditation ........................................................................................ 1983
Faculty Participation Subcommittee of Minority Affairs Committee ................................ 1983-1984
Physiology Representative-Faculty Grievance Committee ............................................. 1986-1990
Minority Affairs Committee ..................................................................................... 1986-1990
Chairman, Physiology Coordinating Committee, Liaison Committee for Medical
Education Accreditation Site Visit ........................................................................... 1987-1989
Department Representative to Faculty Senate ............................................................ 1988-1991,1999
Faculty Senate Representative to Academic Governing Council ..................................... 1988-1989,1999
Vice Chairman, Faculty Senate ................................................................................ 1989-1991,1999
Faculty Senate Representative to Executive Committee of the
Academic Governing Council ................................................................................. 1989-1991,1999
Member, Minority Screening Subcommittee of the Medical School Admissions
Committee .......................................................................................................... 1989-1991
Search Committee for Chairman of Anesthesiology ..................................................... 1989
Member, Academic Governance Task Force ............................................................... 1990-1991
Scope of Search Committee for Chairman of Anatomy ................................................ 1991
Chairman, Search Committee for Chair of Anatomy .................................................... 1991-1992
Commencement Committee .................................................................................... 1991-1998
Library Advisory Committee .................................................................................... 1991-1998
Academic Governing Council ................................................................................... 1991-1998
Executive Committee of Academic Governing Council ................................................ 1991-1998
Committee on College Affairs, Invited Guest .............................................................. 1991-1993
Research Advisory Committee ................................................................................. 1991-1994
Continuing Medical Education Committee, Basic Science Chair ..................................... 1992-1995
Selection Committee MD with Distinction in Research ................................................ 1992-1998
Scientific Advisory Board ........................................................................................ 1994-1998
Education Priority Task Force .................................................................................. 1995-1996
Liaison Committee for Medical Education- Self Study Preparation ................................. 1995-1996
-- Institutional Self Study Task Force
-- Subcommittee on Institution Reports
-- Chair, Subcommittee on Graduate Education in the Sciences Basic to Medicine
Search Committee for Director of Experimental Pathology ............................................ 1996
Academic Strategic Planning and Quality Council ........................................................ 1996-1998
5

-- Academic Quality Council Planning Group
-- Education Quality Improvement Team
-- Chair, Customer Relations Quality Improvement Team
MSA Accreditation Self Study Steering Committee ..................................................... 1996-1998
-- Chair, MSA Self Study Committee - Graduate Studies Research Team
Member, First and Second Year Promotions Committee .............................................. 1998-1999
Member, Comprehensive Care Case Studies Advisory Committee…………………………….1999-
Undergraduate Medical Education Council………………………………………………………….2000-
Committee to Implement Public Health Service-Responsible Conduct of Research Requirement and Chair of the
Working Committee…………………………………………………………………………………….2000-
RPI/AMC Biomedical Program-Joint Curriculum Committee………………………………………2000-
GRADUATE PROGRAM
Physiology Representative, Committee for Admissions & Student Evaluation of the
Graduate Studies Program ...................................................................................... 1977-1985
Secretary, Committee for Admissions & Student Evaluation ......................................... 1979-1983
Chairman, Committee for Admissions & Student Evaluation ......................................... 1984-1986
Chairman, Subcom. Development of Combined Residency-Graduate Program .................. 1985-1986
Chairman, Subcommittee for Assessment of Ph.D. Thesis Requirements ........................ 1980
Member, Executive Faculty of Graduate Studies Program ............................................. 1984-1986
Member, Community Day Committee of Graduate Studies Program .............................. 1978
Chairman, Graduate Student Awards Day Committee .................................................. 1980-1994
Coordinator,Self Study-Dept. Physiology for New York State Doctoral
Program Accreditation .......................................................................................... 1982-1983
Member, Subcommittee on the Relationship of Research to Graduate Education
of the Coordinating Committee for Middle States Association
Accreditation Site Visit ......................................................................................... 1986-1987
Member, Catalog and Rules Committee, Graduate School ............................................ 1987-1991
Chairman, MSA Accreditation Self Study Committee-Student Affairs ............................ 1988-1989
Member, New York State Doctoral Review Self Study Committee of
Graduate School Governance ................................................................................. 1990-1991
Associate Dean ..................................................................................................... 1991-1998
Chairman, Executive Committee, Graduate Studies Program ......................................... 1991-1998
Coordinator, MSA Periodic Review Report ................................................................. 1994
Albany Medical Center:
Member, Radioisotope & Radiation Safety Committee and
Chairman, Subcommittee on Research Protocol Review ............................................. 1988-1991
Member, Academic Facilities Redevelopment Committee ............................................. 1988-1989
Safety Committee .................................................................................................. 1992-1996
Improvement Team (to implement Total Quality Improvement) ...................................... 1993-1994
-- Working Group - Assessment and Measurement
-- Working Group - Improvement Action System
-- Process Improvement Team Facilitator - Purchasing for Research
Board of Trustees, Invited Guest .............................................................................. 1994-1998
Annual Fund Drive, Basic Science Chair .................................................................... 1994-1996
Strategic Planning Committee .................................................................................. 1994-1996
-- Research Tack Force, Co-Chair ........................................................................... 1995
-- Education Tack Force ........................................................................................ 1995
Organizational Framework Implementation Team ....................................................... 1995-1996
Organizational Framework Communication Design Team ............................................. 1995-1996
Quality Council ...................................................................................................... 1996-1998
Quality Council Customer Service Team .................................................................... 1996-1997
SUNYA School of Public Health Science:
Curriculum Committee, Department of Biomedical Sciences (Deputy Chairman) ............... 1987-1990
Student Recruitment Committee .............................................................................. 1988-1989
Biomedical Sciences Executive Committee (as AMC Liason) ......................................... 1997-1998
6

OTHER RESEARCH, EDUCATIONAL and VOLUNTEER ACTIVITIES:
Site Visit and Study Section Consultant:
National Institute of General Medical Sciences, Center Grant Site Visit, August 1982
National Heart, Lung and Blood Institute, Program Project Site Visit, October 1982
American Heart Association, Peer-Review Certification Site Visit, New York City, 1987
Special Emphasis Panel, National Heart, Lung and Blood Institute - Clinical Investigator
Development Award, 1992
National Institute of General Medical Sciences, Training Grant Site Visit, March 1994
National Institute of Health Lung Biology and Pathology Study Section, October 1995
National Institute of Health Lung Biology and Pathology Special Emphasis Panel, December 1995
Ad Hoc Reviewer For:
Arthritis Society
National Science Foundation
National Research Council of Canada
American Institute for Biological Science (Army Combat Casualty Care and Office of Naval Research
Grants)
Respondent to:
National Research Council Assessment of Physiology Doctoral Programs
Volunteer Activities:
Chairman, Ad Hoc Committee of Board of Education to Review Programs for Gifted and
Talented Students, Bethlehem, NY…………………………………………………………………1983-1984
Long-Range Planning Committee, Bethlehem Central Schools, Bethlehem, NY……………. 1994-1995
Board of Directors, Albany Medical College - Alumni Association……………………………. 1995-date
Nominating Committee………………………………………………………………………………1996-date
Membership Committee……………………………………………………………………………..2000-date
Committee on Spending Guidelines……………………………………………………………….2000-date
Consultant, Research Course, Bethlehem Central High School……………………………….. 1996-date
Board of Directors, Science Technology and Engineering Mentors…………………………….1998-date
Vice President, Science Technology and Engineering Mentors……………………………….. 1999-date
American Heart Association:
Member, Peer-Review Committee, New York State Affiliate ....................................... 1983-1987
Member, Long Range Planning Committee, New York State Affiliate ........................... 1985-1986
Chairman, Peer-Review Committee, New York State Affiliate ..................................... 1985-1987
Member, Research Committee, New York State Affiliate ........................................... 1985-1987
New York State Representative, Upper Atlantic Research Committee .......................... 1985-1987
Chairman, Research Committee, New York State Affiliate .......................................... 1987-1989
Member, Affiliate Cabinet, New York State Affiliate .................................................. 1987-1988
Board of Directors, Northeastern New York Chapter, New York State Affiliate .............. 1987-1990
President-Elect, Northeastern New York Chapter, New York State Affiliate ................... 1988-1989
President, Northeastern New York Chapter, New York State Affiliate .......................... 1989-1992
Scientific Advisor, Northeastern New York Chapter, New York State Affiliate ............... 1990-1994
Executive Committee, Northeastern New York Chapter, New York State Affiliate .......... 1990-1994
Member, Program Committee, New York State Affiliate ............................................ 1989-1991
Director-At-Large, New York State Affiliate ............................................................. 1988-1991
Secretary, Board of Directors, New York State Affiliate ............................................. 1991-1992
Chairman, Long Range Planning Committee ............................................................. 1991-1992
Member, Albany County Council ............................................................................ 1990-1996
Division Task Force, New York State Affiliate .......................................................... 1992-1993
Chairman, Community Organization Committee, Northeastern New York Area .............. 1992-1993
7

RESEARCH SUPPORT
As Principal Investigator:
Grant Support
Heart Association of Northeastern New York ................................................................ 1977-1978
[Reticuloendothelial Clearance of Coagulation Products]
National Institutes of Health (GM-25946) .................................................................... 1978-1985
[Phagocytic Control of Thrombosis During Sepsis]
Upjohn Company ...................................................................................................... 1978-1979
[Steroid Effects on Reticuloendothelial System Function Trauma and Sepsis]
National Institutes of Health (P41-GM-27405) (Shared Instrumentation Program) ............... 1979-1983
[Scintigraphic Evaluation of Physiological Events]
Alexandrine and Alexander R. Sinsheimer Fund ............................................................. 1980-1983
[Fibronectin in Thrombosis and Vascular Injury]
National Institutes of Health (GM-00488) (Research Career Development Award) .............. 1980-1985
[Phagocytic Control of Thrombosis During Sepsis]
Abbott Laboratories .................................................................................................. 1983-1984
[Studies of Monkey Fibrinogen]
Sterling-Winthrop Research Institute ........................................................................... 1983-1986
[Role of Fibronectin in Rheumatoid Arthritis]
Upjohn Company ...................................................................................................... 1984-1986
[Cyclooxygenase Products and Reticuloendothelial Function]
National Institutes of Health (HL-39536) (Small Instrumentation Program) ........................ 1987-1988
[Platelet Ionized Calcium Aggregometer and Others]
National Institutes of Health (HL-32418) (Program Project) ............................................. 1985-1990
[Pathophysiology of Pulmonary Vascular Injury and Edema; Program Director - Dr. Asrar Malik]
[PI of Section 5 - Effect of Platelet Aggregation on Pulmonary Endothelial Permeability]
American Heart Association, New York State Affiliate ................................................... 1990-1991
[Fibronectin in Macrophage Fibrin Binding and Degradation]
National Institutes of Health (P01-GM-40761) (Program Project) ..................................... 1991-1997
Tissue Injury and Repair: Fibronectin and Macrophages; Program Director
PI of Core; PI of Project 1 - Fibronectin in Macrophage Fibrin Binding and Degradation
American Heart Association New York State Affilliate .................................................. 1996-1999
Fibronectin and the Platelet Response to Vascular Surgery Injury
8

As Co-Investigator:
National Institutes of Health (GM-26l02) ...................................................................... 1979-1981
[Hemolysis and Phagocytic Dysfunction During Shock; PI - Dr. Daniel Loegering]
National Institutes of Health (AI-l7635) ....................................................................... 1981-1983
[Fibronectin Co-Factors and Macrophage Phagocytosis; PI - Dr. Frank Blumenstock]
National Institutes of Health (HL-17355) ...................................................................... 1981-1986
[Pulmonary Vascular Adjustments in Circulatory Collapse; PI - Dr. Asrar Malik]
American Heart Association - New York State Affiliate .................................................. 1985-1987
[Role of Fibronectin in Fibrinolysis; PI - Dr. Nissan Gilboa]
National Institutes of Health (GM-15426) (Center Grant) ................................................ 1979-1990
[On Line Computer Study of Therapy for Human Shock; PI - Dr. Dhiraj Shah]
[Co-Investigator on Section - Plasma Fibronectin Turnover in Septic Injured Patients]
National Institutes of Health (R01-GM-21447) .............................................................. 1977-1991
[Systemic Host Defense Following Trauma; PI - Dr. Thomas Saba]
American Heart Association (920-06960) .................................................................... 1992-1995
[Platelet Effect on Pulmonary Vascular Barrier Function - Dr. Fred L. Minnear]
Training Grant Staff Member:
National Heart Lung & Blood Institute (T32-HL-07194) .................................................. 1976-1999
[Predoctoral Training Grant - Cardiovascular Disease Training]
National Institute of General Medical Sciences (T32-GM-07033) ..................................... 1975-1999
[Postdoctoral Training Grant - Basic & Clinical Science Trauma Research Training]
National Heart, Lung & Blood Institute (T32-HL-07529) ................................................. 1981-1999
[Postdoctoral Training Grant – Mechanisms & Treatment of Pulmonary Edema]
9

INVITED LECTURES, SYMPOSIA, and RELATED ACTIVITIES:
Department of Physiology, Chicago Medical School ...................................................... March 1977
"Reticuloendothelial Function During Shock"
Symposium on the Pathogenesis of Liver Disease, Wurzburg, Germany ........................... Oct. 1979
"Physiological and Pathophysiological Factors Determining Phagocytosis"
Department of Physiology, University of Illinois Medical School ...................................... Oct. 1980
"Fibronectin, The Reticuloendothelial System and Thrombosis"
Respiratory Physiology Seminar, Univ. Pennsylvania School of Medicine ......................... Nov. 1981
"Relationship of Fibronectin and the Reticuloendothelial System to Thrombosis"
Symposium on Liposomes and Targeted Chemotherapy, San Francisco, CA ..................... Nov. 1981
"The Reticuloendothelial System"
Hematology/Oncology Conference, Albany Medical College ............................................ April 1982
"The Reticuloendothelial System, Fibronectin and Thrombosis"
Session Chairman, FASEB Meeting, Chicago, IL ............................................................ April 1983
"Cell Biology of Platelets and White Cells"
Guest Seminar Speaker, Veterans Administration Medical Center, Albany, NY .................. May 1983
Symposium Organizer, 6th National Meeting, Shock Society Meeting ............................. June 1983
"Hematological Consequences of Shock"
Symposium Speaker, Shock Society ........................................................................... June 1983
"The Role of Fibronectin in Shock"
Guest Speaker, American Heart Assoc. Annual Meeting - Mid-Hudson Chapter ................. June 1986
Guest Seminar Speaker, Veterans Administration Medical Center, Albany, NY .................. Dec. 1986
Presenter of Research Workshop, American Heart Association Annual Meeting
New York State Affiliate ....................................................................................... June 1988
Seminar Speaker, Department of Biochemistry, Albany Medical College ........................... Nov. 1988
Guest Faculty, Hemostasis Conference, Michigan State University,
East Lansing, MI .................................................................................................. May 1990
Seminar Speaker, Cardeza Foundation for Hematologic Research,
Jefferson Medical College, Philadelphia, PA ............................................................. April 1991
Chairman, Planning Retreat, American Heart Association,
New York State Affilliate ...................................................................................... Nov. 1991
Guest Seminar Speaker, Veterans Administration Medical Center, Albany, NY .................. Feb. 1993
Moderator, Twelfth Annual Awards Program for Medical Student Research -
Associated Medical Schools of New York ................................................................ May 1993
Participant, Executive Development Seminar for Associate Deans and Department Chairs,
American Associate of Medical Colleges……………………………………………………….. Oct. 1993
Judge, New York State High School Science and Humanities Symposium………………….. May 1996
Judge, Capital District Science and Engineering Fair…………………………………………….. March 1997
Guest Panelist, Sigma Xi Meeting - Instruction in Scientific Integrity…………………………. March 1997
Judge, New York State High School Science and Humanities Symposium……………………April 1997
Judge, New York State High School Science and Humanities Symposium……………………April 1998
Facilitator, American Association of Medical Colleges-Group on Graduate Research
Education and Training. Discussion on Jobs in Biotechnology……………………………….Oct. 1998
Judge, Science Fair, Albany Academy………………………………………………………………Feb. 1999
Guest Speaker, College of Saint Rose………………………………………………………………..March 1999
“Effect of the Media on the Public Perception of Biomedical Science”
Judge, New York State High School Science and Humanities Symposium……………………March 1999
Judge, John Henry Science Fair, City Schools of Albany…………………………………………April 1999
10

PUBLICATIONS
Full Manuscripts:
Ryder, K.W., Jr., Kaplan, J.E. and Saba, T.M.: Serum calcium and hepatic Kupffer cell phagocytosis.
Proc. Soc. Exp. Biol. Med. 149:163-167, 1975.
Kaplan, J.E.: Mechanisms of reticuloendothelial system depression following trauma. Doctoral Thesis,
Albany Medical College of Union University, Albany, New York, pp. 1-178, 1975.
Kaplan, J.E. and Saba, T.M.: Humoral deficiency and reticuloendothelial depression after traumatic shock.
Am. J. Physiol. 230:7-14, 1976.
Malik, A.B., Kaplan, J.E. and Saba, T.M.: Reference sample method for cardiac output and regional blood
flow determinations in the rat. J. Appl. Physiol. 40:472-475, 1976.
Kaplan, J.E., Saba, T.M. and Cho, E.: Serological modification of reticuloendothelial capacity and altered
resistance to traumatic shock. Circ. Shock 3:203-210, 1976.
Malik, A.B., Loegering, D.J., Kaplan, J.E. and Saba, T.M.: Regional blood flow following traumatic shock.
In: Microcirculation, volume 2 (J. Grayson and W. Zingg, eds.), New York, Plenum Press, pp. 164-166,
1976.
Loegering, D.J., Kaplan, J.E. and Saba, T.M.: Elevation of plasma lysosomal enzyme levels after trauma in
association with impairment of hepatic reticuloendothelial function. In: Microcirculation, volume 2 (J.
Grayson and W. Zingg, eds.), New York, Plenum Press, pp. 242-243, 1976.
Scovill, W.A., Saba, T.M., Kaplan, J.E., Bernard, H. and Powers, S.: Deficits in reticuloendothelial humoral
mechanisms after trauma. J. Trauma 16:898-904, 1976.
Kaplan, J.E., Molnar, J., Saba, T.M. and Allen, C.: Comparative disappearance and localization of
isotopically labelled opsonic protein and soluble albumin following surgical trauma. J. Reticuloendothelial
Soc. 20:375-384, 1976.
Loegering, D.J., Kaplan, J.E. and Saba, T.M.: Correlation of plasma lysosomal enzyme levels with hepatic
reticuloendothelial function after trauma. Proc. Soc. Exp. Biol. Med. 152:42-46, 1976.
Kaplan, J.E., Scovill, W.A., Bernard, H.R., Saba, T.M. and Gray, V.C.: Reticuloendothelial phagocytic
response to bacterial challenge after traumatic shock. Circ. Shock 4:1-12, 1977.
Kaplan, J.E. and Saba, T.M.: Alpha-2-glycoprotein opsonic deficiency after trauma. Proc. Soc. Exp. Biol.
Med. 156:14-18, 1977.
Scovill, W.A., Saba, T.M., Kaplan, J.E., Bernard, H.R. and Powers, S.R., Jr.: Disturbances in circulating
opsonic activity in man after operative and blunt trauma. J. Surg. Res. 22:709-716, 1977.
Malik, A.B., Loegering, D.J., Saba, T.M. and Kaplan, J.E.: Cardiac output and regional distribution of
blood flow following trauma. Circ. Shock 5:61-71, 1977.
Kaplan, J.E. and Saba, T.M.: Low-grade intravascular coagulation and reticuloendothelial function. Am. J.
Physiol. 234:H323-H329, 1978.
Kaplan, J.E. and Saba, T.M.: Platelet removal from the circulation by the liver and spleen.
235:H314-H320, 1978.
Am. J. Physiol.
Kaplan, J.E., Blumenstock, F.A. and Saba, T.M.: A radial immunodiffusion method for the measurement of
rat fibrinogen and fibrin degradation products. Vox Sanguinis 36:65-71, 1979.
11

Kaplan, J.E.: Effect of reticuloendothelial blockade on the development of hypotension after trauma,
sepsis and intravascular coagulation. Adv. Shock Res. 2:73-82, 1979.
Kaplan, J.E. and Saba, T.M.: Immunoreactive serum opsonic α2SB glycoprotein as a non-invasive index of
RES systemic defense after trauma. Adv. Shock Res. 2: 83-92, 1979.
Kaplan, J.E.: Influence of methylprednisolone on reticuloendothelial phagocytic and opsonic function
during traumatic and septic shock. Adv. Shock Res. 4: 11-25, 1980.
Kaplan, J.E. and Snedeker, P.W.: Maintenance of fibrin solubility by plasma fibronectin.
96:1054-1061, 1980.
J. Lab. Clin. Med.
Kaplan, J.E. and Saba, T.M.: Enhancement of reticuloendothelial activity by low-dose heparin during intravascular
coagulation in rats. J. Reticuloendothelial Soc. 29:381-393, 1981.
Blumenstock, F.A., Roccario, E., Cho, E., Saba, T.M. and Kaplan, J.E.: Evaluation of circulating fibronectin
activity utilizing a peritoneal macrophage monolayer microbioassay. J. Reticuloendothelial Soc. 30:61-
72, 1981.
Ehrlich, M.I., Krushell, J.S., Blumenstock, F.A. and Kaplan, J.E.: Depression of phagocytosis by plasmin
degradation products of plasma fibronectin. J. Lab. Clin. Med. 98:263-271, 1981.
Aukburg, S.J. and Kaplan, J.E.: The influence of elevated fibronectin levels during sepsis on the
distribution of blood-borne particles. Adv. Shock Res. 6:37-44, 1981.
Malik, A.B., Tahamont, M.V., Minnear, F.L., Johnson, A. and Kaplan, J.E.: Lung fluid and protein
exchange after pulmonary thrombosis: Role of formed elements. Chest 81S:54S-56S, 1982.
Kaplan, J.E.: Plasma fibronectin and resistance to thrombosis during sepsis. Adv. Shock Res.
1982.
12
7:159-172,
Johnson, A., Tahamont, M.V., Kaplan, J.E. and Malik, A.B.: Lung fluid balance after pulmonary embolization:
effects of thrombin vs. fibrin aggregates. J. Appl. Physiol. 52:1565-1590, 1982.
Minnear, F.L., Moon, D.G., Kaplan, J.E. and Malik, A.B.: Effect of ADP-induced platelet aggregation on
lung fluid balance in sheep. Am. J. Physiol. 242: H645-H651, 1982.
Loegering, D.J., Kaplan, J.E. and Grover, G.J.: Effect of erythrocyte stroma on reticuloendothelial system
phagocytic function. J. Lab. Clin. Med. 102:231-239, 1983.
Kaplan, J.E., Baum, S.H., Snedeker, P.W., Moon, D.G. and Minnear, F.L.: Influence of plasma fibronectin
on the response to infusion of thrombin and adenosine diphosphate. Thrombosis Haemostasis 49:217-
22, 1983.
Kaplan, J.E., Moon, D.G., Minnear, F.L. and Saba, T.M.: Depressed reticuloendothelial clearance of altered
platelets after trauma. Am. J. Physiol. 246: (Heart Circ. Physiol. 15):H180-H188, 1984.
Saba, T.M., Blumenstock, F.A., Shah, D.M., Kaplan, J.E., Cho, E., Scovill, W.A., Newell, J.C., Gottlieb,
M., Stratton, H.H., Sedransk, N. and Rahm, R.: Reversal of fibronectin and opsonic deficiency in
patients: A controlled study. Ann. Surg. 199:87-96, 1984.
Rourke, F.J., Blumenstock, F.A. and Kaplan, J.E.: Effect of fibronectin fragments on macrophage uptake
of gelatinized particles. J. Immunol. 132:1931-1936, 1984.
Glass, M., Aukburg, S., Kaplan, J.E., Macarak, E.J. and Fisher, S.B.: Serum fibronectin is elevated during
normobaric and hyperbaric oxygen exposure. Am. Rev. Resp. Dis. 130:237-241, 1984.
Cooper, J.A., Solano, S.J., Bizios, R., Kaplan, J.E. and Malik, A.B.: Pulmonary neutrophil kinetics after
thrombin-induced intravascular coagulation. J. Appl. Physiol. 57:826-832, 1984.

Johnson, A., Garcia-Szabo, R., Kaplan, J.E. and Malik, A.B.: Fibrin degradation products increase lung
transvascular fluid filtration after thrombin-induced pulmonary microembolism. Thromb. Res. 37:543-
554, 1985.
Weinberg, D.A., Weston, L.K. and Kaplan, J.E.: Influence of prostaglandin I 2 on fibronectin mediated
phagocytosis in vivo and in vitro. J. Leukocyte Biol. 37:151-159, 1985.
Connolly, K., Stecher, V.J., Saelens, J.K., Kaplan, J.E. The relationship between plasma fibronectin levels
and autoimmune disease activity in MRL/1 mice. Proc. Soc. Exp. Biol. Med. 180:149-154, 1985.
Connolly, K., Stecher, V.J., Kaplan, J.E., Mielens, Z., Rostemi, H.J. and Saelens, J.K. The effect of antiinflammatory
drugs on plasma fibronectin. J. Rheumatol. 12:758-762, 1985.
Loegering, D.J., Moon, D.G., Kaplan, J.E., Weber, P. and Blumenstock, F.A. Reticuloendothelial
depressing substance: Studies on the mechanism of action. J. Leukocyte Biol. 38:613-624, 1985.
Gilboa, N. and Kaplan, J.E. Plasma fibronectin enhances fibrinolytic system in vivo. Thrombosis
Haemostasis 54(3):639-644, 1985.
Moon, D.G., Kaplan, J.E. and Mazurkiewicz, J.E. The inhibitory effect of plasma fibronectin on collageninduced
platelet aggregation. Blood 67:450-457, 1986.
Stecher, V.J., Kaplan, J.E., Connolly, K., Mielens, Z., Saelens, J.K. Fibronectin in acute and chronic
inflammation. Arthritis and Rheumatism 29:394-399, 1986.
Burhop, K.E., van der Zee, H., Bizios, R., Kaplan, J.E. and Malik, A.B. Platelet activating factor: Pulmonary
vascular response in awake sheep and role of cyclooxygenase metabolites. Am. Rev. Resp. Dis.
134:548-554, 1986.
Cerda, J., Urizar, R.E., Conran, R., Blumenstock, F.A., Kaplan, J.E., Malik, A.B. and Simon, R. Disseminated
intravascular coagulation (DIC) induced by liquid (polymetholsulfonate) in the rat. V. Effects on
circulating fibronectin. Brit. J. Exp. Pathol. 67:623-628, 1986.
Burhop, K.E., Garcia, J.G.N., Selig, W.M., Lo, S.K., van der Zee, H., Kaplan, J.E. and Malik, A.B. Platelet
activating factor increases lung vascular permeability to protein. J. Appl. Physiol. 61:2210-2217, 1986.
Ciaglowski, R.E., Moon, D.G., Weston, L.K. and Kaplan, J.E. Thrombin induced fibronectin binding to rat
platelets: Relationship to other inducing agents. Ann. N.Y. Acad. Sci. 485:396-399, 1986.
Schreir, H., Abra, R.M., Kaplan, J.E. and Hunt, C.A. Murine plasma fibronectin depletion after intravenous
injection of liposomes. Internat. J. Pharmaceutics 37:233-238, 1987.
Lo, S.K., Burhop, K.E., Kaplan, J.E. and Malik, A.B. Role of platelets in maintenance of pulmonary
vascular permeability to protein. Am. J. Physiol. 254:H763-H771, 1988.
Loegering, D.J., Kaplan, J.E., Vincent, P.A. and Saba, T.M. Kupffer cell complement receptor clearance
function after surgical injury and phagocytosis of immune complexes: Effect of changes of plasma
fibronectin. J. Lab. Clin. Med. 111:504-510, 1988.
McCandless, B.K., Kaplan, J.E., Cooper, J.A., Malik, A.B. Platelet kinetics after pulmonary microembolism
in sheep. J. Appl. Physiol. 65:1716-1722, 1988.
Kaplan, J.E., Cardarelli, P.M., Rourke, F.J., Weston, L.K., Blumenstock, F.A. Fibronectin augments macrophage
uptake of fibrin. J. Lab. Clin. Med. 113:168-176, 1989.
Venturini, C.M., Del Vecchio, P.J. and Kaplan, J.E. Thrombin induced platelet adhesion is modified by
endothelial derived relaxing factor (EDRF). Biochem. Biophys. Res. Commun. 157:349-354, 1989.
Shepard, J.M., Moon, D.G., Weston, L.K., Del Vecchio, P.J., Minnear, F.L., Malik, A.B., and Kaplan, J.E.
13

Platelets decrease albumin permeability of endothelial cell monolayers. Microvasc. Res. 37:256-266,
1989.
Kaplan, J.E., Moon, D.G., Weston, L.K., Minnear, F.L., Del Vecchio, P.J., Shepard, J.M. and Fenton, J.W.
II: Platelets adhere to thrombin treated endothelial cells in vitro. Am. J. Physiol. 257:H423-H433,1989.
Thompson, C., Blumenstock, F.A., Saba, T.M., Feustel, P.J., Kaplan, J.E., Fortune, J.B., Hough, L. and
Gray, V. Plasma fibronectin synthesis in normal and injured humans as determined by stable isotope
incorporation. J. Clin. Invest. 84:1226-1235, 1989.
Venturini, C.M., Fenton, J.W. II, Minnear, F.L. and Kaplan, J.E.: Platelets adhere to thrombin-treated lungs
under flow conditions. Thrombosis and Haemostasis 62:1006-1010, 1989.
Moon, D.G., van der Zee, H., Morton, K.A., Kaplan, J.E. and Fenton, J.W. II. Platelet activating factor and
sheep platelets. A sensitive bioassay. Thromb. Res. 57:551-564, 1990.
Moon, D.G., Minnear, F.L., Weston, L.K., Hill, L.A., Gudewicz, P.W., Fenton, J.W. II, and Kaplan, J.E.
Thrombin-induced platelet neutrophil interactions. Thrombosis Haemostasis 63:91-96, 1990.
van der Zee, H., Moon, D.G., Kaplan, J.E., Gudewicz, P.W. and Fenton, J.W. II. Thrombin-induced
leukopenia and thrombotyopenia is attenuated by PAF antagonist WEB 2086. J. Lab. Clin. Med.
117:305-312, 1991.
Tloti, M.A., Moon, D.G., Weston, L.K. and Kaplan, J.E. Effect of 13-Hydroxyoctadeca-9,11-Dienoic Acid
(13-HODE) on thrombin induced platelet adherence to endothelial cells in vitro. Thrombosis Res.
62:305-317, 1991.
Blystone, S.D., Weston, L.K. and Kaplan, J.E.: Fibronectin dependent macrophage fibrin binding.
78:2900-2907, 1991.
Blood
Horvath, C.J., Kaplan, J.E. and Malik, A.B.: Role of platelet-activating factor in mediating Tumor Necrosis
Factor Alpha-induced pulmonary vasoconstriction and plasma-lymph protein transport. Am. Rev. Resp.
Dis. 144:1337-1441, 1991.
Blystone, S.D. and Kaplan, J.E.: Isolation of an amino-terminal fibronectin binding protein on human U937
cells and rat peritoneal macrophages. J. Biol. Chem. 267:3968-3975, 1992.
Paty, P.S.K., Sherman, P.F., Shepard, J.M., Malik, A.B. and Kaplan, J.E. The role of adenosine in platelet
mediated reduction in pulmonary vascular permeability. Am. J. Physiol. 262:H771-H777, 1992.
Venturini, C.M., Weston, L.K. and Kaplan, J.E.: Platelet cGMP, but not cAMP, inhibits thrombin induced
platelet adhesion to pulmonary vascular endothelium. Am. J. Physiol. 263:H606-H612, 1992.
Kaplan, J.E.: Biomedical Research Training Must Remain a Priority. Academic Medicine 68:61, 1993.
Moon, D.G., Matayoshi, B.M., Weston, L.K., Minnear, F.L. and Kaplan, J.E.: Fibronectin inhibition of
platelet thrombus formation in an in vivo porcine model of vascular injury. Thrombosis Research
76:343-351, 1994.
Penc, S.F., Blumenstock, F.A. and Kaplan, J.E.: A role for a 70 kD amino-terminal fibronectin fragment in
soluble gelatin binding by rat peritoneal macrophages. Journal of Leukocyte Biology , 58:501-509,
1995.
Patil, S., Kaplan, J.E., Minnear, F.L.: Protein, not adenosine or adenine nucleotides, mediates platelet
decrease in endothelial permeability. Am J Physiol 273:H2304-H2311, 1997.
Penc, S., Blumenstock, F.A., Kaplan, J.E.: A 70 kD amino terminal fibronectin fragment supports gelatin
binding to macrophages and decrease gelatinase activity. J Leukocyte, 64:351-357, 1998.
14

Invited Reviews and Book Chapters:
Saba, T.M., Blumenstock, F.A., Weber, P. and Kaplan, J.E.: Physiologic role for cold insoluble globulin in
system host defense: Implications of its characterization as the opsonic α2SB glycoprotein. Ann. N.Y.
Acad. Sci. 312:43-55, 1978.
Kaplan, J.E.: Physiological and pathophysiological factors determining phagocytosis. In: The Reticuloendothelial
System and Liver Disease (H. Liehr & M.R. Grun, eds.), Amsterdam, The Netherlands, Elsevier/-
North Holland Press, pp. 55-68, 1980.
Kaplan, J.E.: The role of the reticuloendothelial system in control of hemostatic and thrombotic mechanisms.
In: Pathophysiology of the Reticuloendothelial System (B.M. Altura and T.M. Saba, eds.), New
York, Raven Press, pp. 111-129, 1981.
Blumenstock, F.A., Saba, T.M. and Kaplan, J.E.: Plasma fibronectin: Biochemical properties and clinical
relevance. In: Proceedings of the Sixth Annual Symposium on Blood Transfusion: Bleeding Problems and
Blood Transfusion. Martinus Nyhoff, pp. 119-131, 1983.
Sherman, L.A. and Kaplan, J.E.: Hemostasis. In: The Reticuloendothelial System, A Comprehensive
Treatise, Volume VIIa, Physiology (J.P. Filkins and S.M. Reichard, eds.), New York, Plenum Press, pp.
221-236, 1984.
Kaplan, J.E. and Moon, D.G.: Platelets. In: The Reticuloendothelial System, A Comprehensive Treatise,
Volume VIIa, Physiology (J.P. Filkins and S.M. Reichard, eds.), New York, Plenum Press, 237-266,
1984.
Kaplan, J.E. and Saba, T.M.: Macrophage metabolism of fibrin: Role of fibronectin. In: Survey of Immunologic
Research - The Year in Immunology-1983. 3:164-168, 1984.
Kaplan, J.E. and Malik, A.B.: Thrombin-induced intravascular coagulation: Role in vascular injury. In:
Seminars in Thrombosis and Hemostasis 13:398-416, 1987.
Moon, D.G. and Kaplan, J.E.: Fibronectin in blood coagulation. In: Fibronectin in Health and Disease
Carsons, ed.). CRC Press Inc., Boca Raton, pp. 147-160, 1989.
Venturini, C.M., Minnear, F.L., Del Vecchio, P.J., Fenton, J.W. II, and Kaplan, J.E.: Thrombin-induced
platelet adhesion to endothelial cells in culture and under flow conditions: Role of endothelium derived
nitric oxide and prostacyclin. In: Endothelium-Derived Relaxing Factors (G. Rubanyi and P. Vanhoutte,
eds.), Karger Press, Basel Switzerland, pp. 315-324, 1990.
Kaplan, J.E. and Malik, A.B.: The contribution of platelets to pulmonary embolism. In: The Platelet in
Health and Disease (C. Page, ed.). Blackwell, Oxford, pp. 210-227, 1991.
Venturini, C.M. and Kaplan, J.E.: Thrombin induces platelet adhesion to endothelial cells. In: Seminars in
Thrombosis and Hemostasis 18:275-283, 1992.
Venturini, C.M. and Kaplan, J.E.: Thrombin-induced platelet adhesion to pulmonary vasculature. In: Lung
Vascular Injury: Molecular and Cellular Response (A. Johnson, T.J. Ferro, eds.), Marcel Dekker, New
York, 11:309-327, 1992.
Saba, T.M., Kaplan, J.E., and Blumenstock, F.A.: Opsonic fibronectin and hepatic host defense: Tissue
injury and organ failure. In: Multiple Systems Organ Failure: Hepatic Regulation of Systemic Host
Defense (G.M. Matuschak, ed.), Marcel Dekker, New York, pp. 99-130, 1993.
Blystone, S.D. and Kaplan, J.E.: Fibronectin in macrophage fibrin binding. A potential mechanism for high
affinity, high capacity clearance of circulating fibrin. Blood Coagulation and Fibrinolysis, 4:769-781,
1993.
Kaplan J.E.: Responsible conduct of research, in Mayer DM, Evidence Based Medicine: A Basic Text.
15
(S.

Cambridge University Press. In Press – publications scheduled for 2003.
Abstracts:
Ryder, K., Jr., Kaplan, J.E. and Saba, T.M.: Serum calcium, ionic strength, and osmolarity as physiologic
factors influencing the phagocytic event. Fed. Proc. 32:438a, 1973.
Kaplan, J.E., Saba, T.M. and Scovill, W.A.: Reticuloendothelial response to injury in adrenalectomized rats.
Physiologist 16:359, 1973.
Kaplan, J.E. and Saba, T.M.: Localization of l25 I opsonic protein in injured tissue following surgery: Its
significance to host resistance to circulating malignant cells. J. Reticuloendothelial Soc. 15:68a, 1974.
Kaplan, J.E., Saba, T.M. and Cho, E. Mechanism mediating reticuloendothelial alterations following
traumatic shock. Fed. Proc. 33:298, 1974.
Kaplan, J.E. and Saba, T.M. Humoral opsonic deficiency in the etiology of hepatic reticuloendothelial
failure following shock. Physiologist 15:257, 1974.
Saba, T.M., Scovill, W.A., Kaplan, J.E., Powers, S.R. and Bernard, H. Humoral parameters of
reticuloendothelial failure following traumatic shock. Physiologist 18:373, 1975.
Kaplan, J.E., Bernard, H.R., Scovill, W.A., Saba, T.M. and Gray, V.C. Relationship of reticuloendothelial
systemic defense to bacterial challenge following trauma. Physiologist 18:272, 1975.
Kaplan, J.E. and Saba, T.M.: Reticuloendothelial dysfunction during disseminated intravascular coagulation:
Relevance to post-shock microembolization. Physiologist 19:248, 1976.
Saba, T.M., Blumenstock, F.A., Weber, P. and Kaplan, J.E.: Electroimmunoassay of serum alpha-2-
opsonic protein as an index of reticuloendothelial clearance: RE failure and traumatic shock. Physiologist
19:348, 1976.
Kaplan, J.E. and Saba, T.M.: Reticuloendothelial dysfunction and its reversal by heparin following
intravascular coagulation. J. Reticuloendothelial Soc. 20:22A, 1976.
Scovill, W.A., Saba, T.M., Kaplan, J.E., Bernard, H.R. and Powers, S.R.: Depressed reticuloendothelial
humoral control following multiple trauma. Assoc. Acad. Surg., presented 1976.
Kaplan, J.E. and Saba, T.M.: Defective reticuloendothelial clearance of platelets after whole-body trauma.
Thrombosis and Haemostasis 38:141, 1977.
Scovill, W.A., Saba, T.M., Kaplan, J.E., Bernard, H. and Powers, S.: Deficits in reticuloendothelial humoral
mechanisms after trauma. Rev. Surg. 34:384, 1977.
Kaplan, J.E. and Saba, T.M.: Reticuloendothelial clearance of platelets as influenced by platelet load and
RES blockade. Physiologist 30:49, 1977.
Saba, T.M., Blumenstock, F.A., Bernard, H. and Kaplan, J.E.: Prevention of reticuloendothelial depression
following surgery by intravenous opsonic glycoprotein administration. J. Reticuloendothelial Soc.
22:31a, 1977.
Kaplan, J.E. and Saba, T.M.: Prevention of opsonic activity by aprotinin mediated proteolytic inhibition. J.
Reticuloendothelial Soc. 22:60a, 1977.
Kaplan, J.E.: Impaired platelet clearance during methylpalmitate induced reticuloendothelial system
depression. Fed. Proc. 37:551, 1978.
16

Kaplan, J.E. and Saba, T.M.: Immunoreactive serum opsonic α2 SB glycoprotein as a non-invasive index of
RES systemic defense after trauma. Circ. Shock 5:188, 1978.
Kaplan, J.E.: Effect of reticuloendothelial blockade on the development of hypotension after trauma,
sepsis and intravascular coagulation. Circ. Shock 5:187, 1978.
Snedeker, P.W., Kaplan, J.E. and Saba, T.M.: Effect of traumatic shock and alteration of reticuloendotheli-
-al function on the vascular clearance of soluble fibrin. Physiologist 21:113, 1978.
Kaplan, J.E.: Influence of methylprednisolone on reticuloendothelial phagocytic and opsonic function
during traumatic and septic shock. Circ. Shock 6:183-184, 1979.
Snedeker, P.W., Kaplan, J.E. and Saba, T.M.: Effect of intravascular coagulation on the vascular clearance
of soluble fibrin monomer. Circ. Shock 6:196-197, 1979.
Kaplan, J.E., Blumenstock, F.A. and Saba, T.M.: Relationship of plasminolysis to reticuloendothelial
function during traumatic shock. Physiologist 22:66, 1979.
Kaplan, J.E. and Snedeker, P.W.: Inhibition of fibrin collagen binding by plasma fibronectin.
39:871, 1980.
Fed. Proc.
Aukburg, S.J. and Kaplan, J.E.: The influence of elevated fibronectin levels during sepsis on the
distribution of blood-borne particles. Circ. Shock 7: 212, 1980.
Snedeker, P.W. and Kaplan, J.E.: Reticuloendothelial clearance and vascular localization of soluble fibrin
monomers. Circ. Shock 7:207, 1980.
Kaplan, J.E., Baum, S.H. and Snedeker, P.W.: Relationship of plasma fibronectin to thrombotic resistance.
Physiologist 23:173, 1980.
Snedeker, P.W. and Kaplan, J.E.: Non-invasive quantitation of reticuloendothelial (RES) function by
dynamic scintigraphy. Fed. Proc. 40:812, 1981.
Blumenstock, F.A., Kaplan, J.E., Erhlich, M.I. and Krushell, J.S.: Depression of reticuloendothelial
phagocytic function by plasma derived fibronectin degradation products. Fed. Proc. 40:769, 1981.
Moon, D.G. and Kaplan, J.E.: Plasma fibronectin inhibition of collagen and ADP-induced platelet aggregation.
Fed. Proc. 40:768, 1981.
Kaplan, J.E.: Plasma fibronectin and resistance to thrombosis during sepsis. Circ. Shock 8:225, 1981.
Malik, A.B., Minnear, F.L., Tahamont, M.V., Moon, D.G. and Kaplan, J.E.: Does ADP-induced platelet
aggregation mediate lung vascular injury. Thrombosis Haemostasis 46:222, 1981.
Moon, D.G. and Kaplan, J.E.: Inhibition of ADP-induced platelet aggregation by plasma fibronectin.
Thrombosis and Haemostasis 46:83, 1981.
Minnear, F.L., Tahamont, M.V., Kaplan, J.E. and Malik, A.B.: The role of platelet aggregation in mediating
pulmonary insufficiency. Anatomical Records 199:174a, 1981.
Aukburg, S., Forman, H., Williams, J., Kaplan, J. and Fisher, A.: Elevated serum fibronectin as an
indicator of oxygen toxicity. Am. Rev. Resp. Dis. 123:200, 1981.
Kaplan, J.E. and Weinberg, D.A.: Depression of reticuloendothelial clearance by prostacyclin.
41:1691, 1983.
Fed. Proc.
Powers, M.R., Bell, D.R., Kaplan, J.E. and Moon, D.G.: Evaluation of capillary permeability in thrombocytopenic
rabbits. Fed. Proc. 41:1498, 1982.
17

Moon, D.G. and Kaplan, J.E.: Protective effect of plasma fibronectin during collagen-induced thrombosis.
Circ. Shock 9:167, 1982.
Gupta, Y.K., Kaplan, J.E. and Balint, J.A.: Fibronectin levels in plasma and peritoneal fluid of patients with
cirrhosis of liver. Presented at American College of Physicians, Upstate New York, October 1982 and
submitted to Gastroenterology Society, 1983 Annual Meeting.
Stecher, V.J., Kaplan, J.E., Connolly, K. and Saelens, J.K.: Plasma levels of fibronectin in normal and
arthritic rats. Arthritis and Rheumatism, 1983.
Moon, D.G. and Kaplan, J.E.: The influence of plasma fibronectin on platelet adherence to collagen in
vitro. Fed. Proc. 42:1355, 1983.
Gilboa, N. and Kaplan, J.E.: Plasma fibronectin enhances activation of plasminogen by tissue plasminogen
activator (TPA) and shortens clot lysis time. Fed. Proc. 42:1030, 1983.
Kaplan, J.E.: Discrimination between fibrin and fibrinogen in fibronectin mediated macrophage responses.
Fed. Proc. 42:1032, 1983.
Rourke, F.J., Blumenstock, F.A. and Kaplan, J.E.: Effect of fibronectin degradation on macrophage uptake
of gelatinized particles. Fed. Proc. 42:1031, 1983.
Gudewicz, P.W., Cardarelli, J.M., Rourke, F.J., Kaplan, J.E., Saba, T.M. and Blumenstock, F.A.: Failure to
stimulate Kupffer cell chemiluminescence during fibronectin mediated uptake of particulate and soluble
molecules. Fed. Proc. 42:695, 1983.
Saba, T.M., Blumenstock, F.A., Shah, D.M., Cho, E., Stratton, H.H., Scovill, W.A., Newell, J.C., Gottlieb,
M., Rahm, R. and Kaplan, J.E.: A controlled study on reversal of fibronectin deficiency in injured
patients: Plasma cryoprecipitate vs cryoprecipitate extracted plasma. Fed. Proc. 42:778, 1983.
Johnson, A., Garcia-Szabo, R.R., Kaplan, J.E. and Malik, A.B.: Plasminogen activation (PA) contributes to
lung vascular injury. Fed. Proc. 42:1108, 1983.
Moon, D.G. and Kaplan, J.E.: Plasma fibronectin inhibits phagocytosis of platelets in vitro.
43:979, 1984.
Fed. Proc.
van Grondelle, A., Moon, D.G., Kaplan, J.E. and Del Vecchio, P.: Apparatus to assess the influence of
shear stress on cultured cells. Fed. Proc. 43:522, 1984.
Kaplan, J.E., Rourke, F.J. and Blumenstock, F.A.: Characteristics of fibronectin-mediated uptake of fibrin
monomer by macrophages. Fed. Proc. 43:603, 1984.
Gilboa, N., Waxner, J., Blum, L. and Kaplan, J.E.: Effect of plasma fibronectin on plasminogen activation
by tissue plasminogen activator, urokinase, renal cortical tissue. Role of lysine binding sites. Thrombosis
Haemostasis 54:105, 1985.
Matayoshi, B.M., Moon, D.G. and Kaplan, J.E.: Reduction of the thrombotic response to vascular injury by
plasma fibronectin. Thrombosis Haemostasis 54:218, 1985.
Kaplan, J.E., Burhop, K., van der Zee, H. and Malik, A.B.: Influence of platelet activating factor on
pulmonary vascular permeability. Presented at New Horizons in Platelet Activating Factor Research,
Hilton Head, SC, October 1985.
Gilboa, N., Waxner, J., Blum, L. and Kaplan, J.E.: Effect of plasma fibronectin on plasminogen activation
by tissue plasminogen activator, urokinase, and renal cortical tissue. Role of lysine-binding sites. Clin.
Res. 33:340A, 1985.
18

Cooper, J.A., McCandless, B.K., Kaplan, J.E., Line, B.R. and Malik, A.B. Relationship of fibrinolysis to
neutrophil and platelet uptake after pulmonary microembolism with fibrin. Am. Rev. Resp. Dis.
133:A273, 1986.
Moon, D.G., Ciaglowski, R.E., Weston, L.K. and Kaplan, J.E.: Thrombin induced fibronectin
binding to rat platelets: Relationship to other inducing agents. For presentation at New York Academy
of Sciences Symposium on Thrombin, February 1986.
Moon, D.G., Weston, L.K., Kaplan, J.E. and Malik, A.B.: Platelet neutrophil interaction: Platelet activation
factor induced superoxide anion production. For presentation at International Conference on Platelet
Activating Factor, October 1986.
Moon, D.G., Hill, L.A., Minnear, F.L., Fenton, J.W. and Kaplan, J.E.: Platelet-neutrophil interactions:
Transmission electron microscopy of thrombin-induced platelet-neutrophil contacts. Fed. Proc. 46:1041,
1987.
Kaplan, J.E., Weston, L.K., Moon, D.G., Del Vecchio, P.J. and Fenton, J.W.: Thrombin and phorbol
myristate acetate (PMA) increase platelet adherence to endothelium. Fed. Proc. 46:971, 1987.
Shepard, J.M., Moon, D.G., Weston, L.K., Del Vecchio, P.J., Minnear, F.L., Malik, A.B. and Kaplan, J.E.:
Platelets decrease permeability of cultured endothelial monolayers. Fed. Proc. 46:979, 1987.
van der Zee, H., Moon, D.G., Krasodomski, J. and Kaplan, J.E.: Sheep platelets and platelet activating
factor (PAF). Fed. Proc. 46:1041, 1987.
Loegering, D.J. and Kaplan, J.E.: Effect of plasma fibronectin levels on the in vivo clearance function of
Kupffer cell complement receptors. Fed. Proc. 46:1432, 1987.
Shepard, J.M., Moon, D.G., Weston, L.K., Burhop, K.E., Malik, A.B. and Kaplan, J.E.: Platelets reduce
albumin permeability of pulmonary endothelial cells. Fed. Proc. 46:1541, 1987.
Del Vecchio, P.J., Judge, T.K., Kaplan, J.E., Bizios, R. and Nehal, K.: Fibronectin is not required for
serum-induced proliferation of human retinal pigment epithelial (HRPE) cells. Invest. Ophthalmol.
28:256, 1987.
Blumenstock, F.A., Thompson, C., Feustel, P., Gray, V., Hough, L., Kaplan, J.E. and Saba, T.M.:
Synthetic rate of plasma fibronectin in humans determined by stable isotope analysis. FASEB J.
2:A1512, 1988.
Minnear, F.L., DeMichele, M.A.A., Weston, L.K. and Kaplan, J.E.: Isoproterenol reduces the thrombininduced
increase in endothelial permeability in vitro in association with an increase in intracellular cAMP
and a decrease in thrombin binding to endothelial cells. FASEB J. 2:A298, 1988.
Venturini, C.M., Krebs, S.W. and Kaplan, J.E.: Platelets adhere to thrombin treated endothelium under
flow conditions. FASEB J. 2:A1163, 1988.
van der Zee, H., Moon, D.G., Morton, K., Fenton, J.W. II, Gudewicz, P.W. and Kaplan, J.E.: The PAF
antagonist WEB 2086 attenuates thrombin-induced leukopenia and thrombocytopenia in sheep. FASEB
J. 2:A1576, 1988.
Moon, D.G., van der Zee, H., Krasodomski, J., Fenton, J.W. II and Kaplan, J.E.: Isolated sheep platelets
are a sensitive bioassay for platelet activating factor. FASEB J. 2:A412, 1988.
Shepard, J.M., Weston, L.K., Sherman, P.F., Malik, A.B. and Kaplan, J.E.: Influence of platelets and
platelet mediators on albumin permeability of pulmonary artery endothelial cells. FASEB J. 2:A1078,
1988.
Kaplan, J.E., Weston, L.K., Moon, D.G., Del Vecchio, P.J. and Fenton, J.W.: Characterization of thrombin
mediated platelet adherence to endothelium. FASEB J. 2:A1163, 1988.
19

Paty, P.S.K., Shepard, J.M., Sherman, P.F., Weston, L.K. and Kaplan J.E.: Role of adenosine in plateletmediated
enhancement of endothelial barrier function. Soc. Univ. Surgeons (presented in Resident's
Program), 1989.
Paty, P.S.K., Sherman, P.F., Shepard, J.M., Weston, L.K., Moon, D.G. and Kaplan, J.E.: Preliminary
characterization of a platelet derived endothelial permeability decreasing factor. FASEB J. 3:A1308,
1989.
Shepard, J.M., Paty, P.S.K., Sherman, P.F., Weston, L.K. and Kaplan, J.E.: Role of adenosine in platelet
mediated enhancement of endothelial barrier function. FASEB J. 3:A1308, 1989.
Kaplan, J.E., Weston, L.K., Venturini, C.M., Del Vecchio, P.J. and Fenton, J.W. II: Platelet adherence to
endothelial cells is promoted by activators of platelet protein kinase C. FASEB J. 3:A305, 1989.
Venturini, C.M. and Kaplan, J.E.: Thrombin-induced platelet attachment to endothelium is modified by
EDRF in vitro and under flow conditions. FASEB J. 3:A304, 1989.
Tloti, M.A., Moon, D.G. and Kaplan, J.E.: Thrombin inhibits 13-hydroxyoctadecadienoic acid (13-HODE)
production by cultured sheep pulmonary artery endothelial cells. FASEB J. 3:A305, 1989.
Moon, D.G., van der Zee, H., Krasodomski, J., Morton, K., Fenton, J.W. II and Kaplan, J.E.: Platelet
modulation of neutrophil production of superoxide anion. FASEB J. 3:A267, 1989.
van der Zee, H., Moon, D.G., Morton, K., Krasodomski, J., Fenton, J.W. II and Kaplan, J.E.: The
role of platelet activating factor in thrombin-induced platelet neutrophil superoxide anion production.
FASEB J. 3:A1142, 1989.
Gudewicz, P.W., Odekon, L.E., Blystone, S.D., Kaplan, J.E., Gilboa, N. and Saba, T.M.: Proteolytic
digestion of plasma fibronectin generates fragments chemotactic for human neutrophils. FASEB J.
3:A913, 1989.
Blystone, S.D. and Kaplan, J.E.: Evidence for amino terminal plasma fibronectin binding by rat peritoneal
macrophages. FASEB J. 3:A305, 1989.
Horvath, C.J., Kaplan, J.E., Moon, D.G. and Malik, A.B.: Role of platelet activating factor (PAF) in the
tumor necrosis factor (TNFa)-induced increase in lung vascular permeability. FASEB J. 3:A696, 1989.
DeMichele, M.A.A., Moon, D.G., Kaplan, J.E., Fenton, J.W. II and Minnear, F.L.: Thrombin increases
permeability of pulmonary artery endothelial cell monolayers by an enzymatic rather than a receptor
binding mechanism. Thrombosis Haemostasis 62:436, 1989.
Venturini, C.M. and Kaplan, J.E.: EDRF modifies thrombin-induced platelet attachment to endothelium in
vitro and under flow conditions. J. Vasc. Med. Biol. 1:121, 1989.
Venturini, C.M., Weston, L.K., and Kaplan, J.E. Modulation of thrombin-induced platelet adhesion to
endothelial cells by 8-bromo-cGMP and L-NMMA, an inhibitor of EDRF release. J. Cell Biol. 109:314a,
1989.
Paty, P.S.K., Kaplan, J.E., Everitt, J., and Malik, A.B. Adenosine reduces pulmonary transcapillary
filtration rate. Soc. Univ. Surgeons (presented in Resident's program), 1990.
Moon, D.G., Kaplan, J.E., Fenton, J.W. II, Weston, L.K. and Beaver, J.A.: Activated platelet binding to
macrophages is mediated by fibrinogen. FASEB J. 4:A834, 1990.
Blystone, S.D., Weston, L.K. and Kaplan, J.E.: Fluid phase interactions between fibronectin and fibrin
mediate fibronectin dependent macrophage fibrin binding. FASEB J. 4:A497, 1990.
Paty, P.S.K., Kaplan, J.E., Everitt, J. and Malik, A.B.: Adenosine reduces pulmonary transcapillary
filtration rate. FASEB J. 4:A1147, 1990.
20

Weston, L.K., Paty, P.S.K. and Kaplan, J.E.: Enhancement of endothelial barrier function by low concentrations
of platelets requires platelet activation. FASEB J. 4:A1148, 1990.
Venturini, C.M. and Kaplan, J.E.: The differential effects of platelet cGMP and cAMP on thrombin induced
platelet adhesion to endothelium. FASEB J. 4:A1148, 1990.
Venturini, C.M. and Kaplan, J.E.: Endothelium derived nitric oxide (EDNO) and CGMP inhibit thrombininduced
platelet adhesion to endothelium. Presented at the IUPHAR Satellite Symposium on EDRF,
1990.
Blystone, S.D. and Kaplan, J.E.: Fibronectin amino-terminal domains enhance macrophage fibrin binding.
Evidence for an amino terminal fibronectin receptor. Circ. Shock 31:26, 1990.
Blystone, S.D. and Kaplan, J.E.: Isolation of an amino-terminal fibronectin binding protein on macrophages.
J. Cell Biol. 111:12a, 1990.
Blystone, S.D., Chung, W.G., and Kaplan, J.E.: Isolation and characterization of an amino-terminal
fibronectin binding protein on macrophages. J. Cell Biol. 115(3):290A, 1991.
Penc, S.F., Blumenstock, F.A., and Kaplan, J.E.: Effect of fibronectin on gelatin uptake by rat peritoneal
macrophages. J. Cell Biol. 115(3):136a, 1991.
Weston, L.K. and Kaplan, J.E.: Effect of fibronectin on plasminogen-dependent and -independent fibrin
degradation by macrophages. J. Cell Biol. 115(3):116A, 1991.
Weston, L.K., Blystone, S.D., Chung, W.G., Cleary, L. and Kaplan, J.E.: Identification of a macrophage
surface protein as a receptor for the amino terminus of fibronectin. J. Leukocyte Biol. suppl 3:49,
1992.
Penc, S.F., Kaplan, J.E. and Blumenstock, F.A.: Soluble gelatin binds to macrophages in both fibronectin
dependent and independent pathways. J. Leukocyte Biol. suppl 3:49, 1992.
Penc, S.F. and Kaplan, J.E.: Rat peritoneal macrophages degrade surface bound and internalized soluble
gelatin in the presence or absence of fibronectin. Molec. Biol. Cell 4:288a, 1993.
Weston, L.K., Blystone, S.D., Chung, W.G., and Kaplan, J.E.: Specific amino-terminal fibronectin binding
to macrophages is inhibited by antibody to a 67 kD cell surface protein. FASEB J. 7:A826, 1993.
Line, B.R., Herrmannsdoerfer, A.J., Kaplan, J.E., Dansereau, R.N., Battles, A. and Blumenstock, F.A.:
Simple model of pulmonary embolism in the rat. J. Nuclear Med. 34:178P, 1993.
Penc, S.F., Blumenstock, F.A. and Kaplan, J.E.: 70 kD amino-terminal fibronectin fragment and soluble
gelatin induces 70 kD mediated 125 I-gelatin binding by rat peritoneal macrophages. FASEB J 8:134a,
1994.
Penc, S.F., Blumenstock, F.A. and Kaplan, J.E.: A 70 kD amino-terminal fibronectin fragment and gelatin
induce augmented macrophage binding of gelatin in the presence of the 70 kD fragement.
Molec. Biol. Cell 5:374a, 1994.
Chung, W.G. and Kaplan, J.E., Adenosine mediated attenuation of amino terminal fibronectin binding to
human peripheral monocytes. Molec. Biol. Cell 5:64a, 1994.
Patil, S.T., Kaplan, J.E. and Minnear, F.L.: Platelet derived factors decrease endothelial cell permeability:
Role of adenosine. Drug Development Res. 31:4, 1994.
Patil, S.T., Kaplan, J.E. and Minnear, F.L.: Preliminary characterization of a platelet-derived factor that
decreases endothelial monolayer permeability. FASEB J. 9:A58, 1995.
21

An, S.S., Minnear, F.L. and Kaplan, J.E.: Effects of fibronection on isolated human platelet morphological
changes and protein tyrosine kinase activity. FASEB J. 9:A542, 1995.
Patil, S.T., Kaplan, J.E., and Minnear, F.L.: A heat resistant factor > 3.5 kD mediates the platelet-induced
decrease in endothelial permeability in vitro. FASEB J. 10:A353, 1996.
Kaplan, J.E., An, S.S., Bhattacharaya, S., Mayes, D., Syed, Y. and Giunta, C.: Spreading of "Non-
Activated" Platelets on Fibronectin is Dependent on α11b ß3. Submitted to Gordon Research Conference
on Wound Repair, May 1997.
Minnear, F.L., Patil, S.T., Blumenstock, F.A., Morton, C.A., Owusu, K., Gonzalez, M., Kaplan, J.E.:
Negatively charged, heat-stabile protein mediated platelet-induced decrease in endothelial permeability
in vitro. Am J Respir Crit Care Med 155:A898, 1997.
22