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Prevalence of IDA in pregnancy - Idpas.org

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Side Effects: IOM Report, 2001<br />

• High dose supplements associated with constipation, nausea,<br />

vomit<strong>in</strong>g, diarrhea<br />

• Less effect at lower dose, with food, slow release<br />

• “Lower Observed Adverse Effect Level” = 60 mg/d suppl + 11 mg<br />

diet = 71 mg/d, and<br />

• “No Observed Adverse Effect Level” = “Upper Limit” = 45 mg/d<br />

“Critical<br />

Study”<br />

Effect<br />

Nausea<br />

Placebo<br />

4<br />

60 mg Fe<br />

6<br />

Gastric pa<strong>in</strong><br />

10<br />

19<br />

Constipation<br />

20<br />

35*<br />

Diarrhea<br />

19<br />

37<br />

All effects<br />

14<br />

25*

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