Abstract Book 2010 - CIMT Annual Meeting
Abstract Book 2010 - CIMT Annual Meeting
Abstract Book 2010 - CIMT Annual Meeting
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Scientific Program <strong>CIMT</strong> <strong>2010</strong> Day 2 (May 27 th )<br />
16<br />
Session 3: Combination Partners for Vaccination<br />
Chairpersons: A. Hoos (New York), G. Schuler (Erlangen)<br />
08:40-09:10 J. Allison (New York)<br />
Immune checkpoint blockade in cancer therapy: New insights and opportunities<br />
09:10-09:40 A. Ribas (Los Angeles)<br />
Immunosensitization: Targeted therapies to improve tumor immunotherapy<br />
09:40-10:20 H. Chen (Bethesda)<br />
CTEP/NCI’s model to facilitate clinical trials for combination between investigational<br />
agents<br />
10:20-10:50 Coffee break<br />
Short talk session IV: CIP-Session<br />
Chairpersons: C. Ottensmeier (Southampton), M. Welters (Leiden)<br />
10:45-11:00 C. Britten (Mainz)<br />
Overview on CIP activities in 2009<br />
11:00-11:20 C. Gouttefangeas (Tuebingen)<br />
Update on the CIP HLA-multimer panels<br />
11:20-11:40 C. Ottensmeier (Southampton)<br />
Plans for the new ELISPOT panels (IVS T cell in UK and freezing medium in Mainz<br />
11:40-12:00 S. Singh (Leiden)<br />
A stable standard sample for harmonisation and validation of T cell assays<br />
12:00-12:20 S. Janetzki (New York)<br />
Influence of harmonization on assay performance – the CIC experience<br />
Short talk session V: Cellular therapy<br />
Chairpersons: M. Kalos (Philadelphia), R. G. Meyer (Mainz)<br />
10:50-11:05 N. Auphan-Anezin (Marseille) (# 045)<br />
Optimizing effector and memory properties of CD8 T cells for adoptive tumor<br />
immunotherapy<br />
11:05-11:20 D. Schendel (München) (# 048)<br />
High avidity T cell clones specific for tumor-associated antigens and how to find them<br />
11:20-11:35 D. Stolle (Mainz) (# 053)<br />
Generation of HCMV-/TAA-bispecific human T cells by either the genetic equipment of<br />
HCMV+ T cells with tumor-reactive TCRs or the combined retroviral transduction of<br />
bulk human T cells with HCMV-/ TAA-specific TCRs<br />
11:35-11:50 A. Bloetz (Mainz) (# 054)<br />
Allo-reactivity to HLA class II mismatch alleles in CD4+ T-cell subsets<br />
11:50-12:05 H. Echchannaoui (Mainz) (# 058)<br />
Evaluation of the safety of p53 TCR gene transfer in a humanized mouse model<br />
Short talk session VI: Tumor biology / interaction with<br />
the immune system<br />
Chairpersons: V. Umansky (Heidelberg), D. Schendel (Munich)<br />
10:50-11:05 M. Ramacher (Heidelberg) (# 091)<br />
Immunosuppression in transgenic mouse melanoma model induced by myeloid de<br />
rived suppressor cells
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