Summary Report 2012 - Boehringer Ingelheim
Summary Report 2012 - Boehringer Ingelheim
Summary Report 2012 - Boehringer Ingelheim
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Value through Innovation<br />
<strong>Summary</strong> <strong>Report</strong> <strong>2012</strong>
BOEHRINGER INGELHEIM<br />
GROUP OF COMPANIES<br />
Amounts in millions of EUR,<br />
unless otherwise indicated <strong>2012</strong> 2011 Change<br />
Net sales 14,691 13,171 12%<br />
by region<br />
Europe 29% 31%<br />
Americas 47% 46%<br />
Asia, Australasia, Africa 24% 23%<br />
by business<br />
Human Pharmaceuticals 93% 93%<br />
Animal Health 7% 7%<br />
Research and development 2,795 2,516 11%<br />
Personnel costs 4,024 3,664 10%<br />
Average number of employees 46,228 44,094 5%<br />
Operating income 1,853 2,272 — 18%<br />
Operating income as % of net sales 12.6% 17.3%<br />
Income after taxes 1,237 1,476 — 16%<br />
Income after taxes as % of net sales 8.4% 11.2%<br />
Shareholders’ equity 6,178 7,466 — 17%<br />
Return on shareholders’ equity 16.6% 22.8%<br />
Cash flow 2,225 2,378 — 6%<br />
Investments in tangible assets 562 458 23%<br />
Depreciation of tangible assets 793 535 48%<br />
2<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> summary report <strong>2012</strong>
usiness year <strong>2012</strong><br />
financial highlights<br />
OUR COMPANY<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> is a research-driven<br />
company dedicated to researching and<br />
developing, manufacturing and marketing<br />
pharmaceuticals that improve health and<br />
quality of life.<br />
Our business areas consist of Human Pharma -<br />
ceuticals and Animal Health. We have more<br />
than 46,000 employees in 140 affi liated companies<br />
worldwide, research and development<br />
(R&D) facilities at six sites worldwide and<br />
20 production plants in 13 countries. R&D<br />
expenditure in Prescription Medicines corresponds<br />
to 22.5% of its net sales.<br />
Our headquarters is at <strong>Ingelheim</strong>, the German<br />
town where the family-owned company was<br />
founded in 1885.<br />
Financial Highlights 3
KEY ASPECTS <strong>2012</strong><br />
andreas barner, wolfram carius, allan hillgrove,<br />
joachim hasenmaier, hubertus von baumbach<br />
(from left to right), the board of managing directors<br />
Dear readers,<br />
Successful long-term, sustainable development of the company,<br />
allied with stable earnings and sound finances, is and<br />
will remain the basis of our independence and is central to<br />
the strategic direction of the <strong>Boehringer</strong> <strong>Ingelheim</strong> group of<br />
companies. Besides independence, the paramount goal is our<br />
most important endeavour to make in equal measure available<br />
a high level of medical progress to patients and physicians<br />
treating them by researching innovative medicines, especially<br />
in indications with urgent medical need.<br />
Growth maintained<br />
In <strong>2012</strong>, <strong>Boehringer</strong> <strong>Ingelheim</strong> was able to build on its successful,<br />
above-market growth from the previous year and<br />
achieved a growth rate of + 11.5%.<br />
4<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> summary report <strong>2012</strong>
usiness year <strong>2012</strong><br />
key aspects <strong>2012</strong><br />
Both our new products, such as the anticoagulant pradaxa®<br />
and the diabetes medication trajenta®, as well as established<br />
products, such as the respiratory medicines spiriva® and<br />
combivent®, were the main growth drivers – all of these<br />
products from our own research.<br />
Stable earnings and financial position in a difficult market<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> made an operating profit of EUR<br />
1,853 million. This corresponds to an operating margin<br />
of 12.6%.<br />
We are satisfied with this result, as the successful operative<br />
business development overall was negatively impacted by a<br />
multitude of one-off and extraordinary effects. These effects are<br />
the result of decisions which we have taken in order to prepare<br />
the group of companies for a changing business environment.<br />
Our financial management aims to ensure liquidity, limit<br />
financial risks and optimise the cost of capital. It is noteworthy<br />
that it allows the overall financing of the group of<br />
companies to maintain our independent, organic growth.<br />
Outlook<br />
We are convinced, on the basis of our established product<br />
portfolio and the successful launches of new products from<br />
our own research and development expected for 2013 and<br />
beyond will sustainably reinforce and expand our position in<br />
the global human and veterinary pharmaceuticals market.<br />
For 2013, we expect to be able to maintain growth and anticipate<br />
a mid-single digit increase in sales compared to the<br />
fi nancial year <strong>2012</strong>.<br />
Key aspects <strong>2012</strong><br />
5
PERSPECTIVES FOR<br />
MEDICAL INNOVATION<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong>’s commitment to emerging science as a<br />
basis for new medicines grows ever stronger. As such, we focus<br />
on studying human disease, the subsets of each disease and<br />
establishing target-disease relationships that enable us to ask<br />
the right questions.<br />
Our aim is to help patients by treating diseases in areas of<br />
high unmet medical need both in our current therapeutic area<br />
focus and in new emerging disease areas. Our R&D activities<br />
include both small molecules and biotherapeutics, thereby<br />
allowing us to choose the most appropriate approach for each<br />
therapeutic concept.<br />
RESEARCH AREAS<br />
[ in focus: six major areas ]<br />
respiratory<br />
diseases<br />
cardiometabolic<br />
diseases<br />
oncology<br />
central nervous<br />
system diseases<br />
immunology<br />
infectious<br />
diseases<br />
6<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> summary report <strong>2012</strong>
perspectives<br />
for medical innovation<br />
OUR RESEARCH AND DEVELOPMENT SITES<br />
[ 3 major and 3 specialised sites ]<br />
2<br />
1<br />
3<br />
4<br />
5<br />
6<br />
1 ridgefield, usa<br />
2 laval, canada<br />
3 biberach and<br />
ingelheim, germany<br />
4 vienna, austria<br />
5 milan, italy<br />
6 kobe, japan<br />
Status 31.12.<strong>2012</strong><br />
THE BOEHRINGER INGELHEIM PIPELINE<br />
[ compounds in development, total 94 ]<br />
17<br />
respiratory<br />
diseases<br />
9<br />
immunology<br />
10<br />
cns diseases<br />
3<br />
infectious<br />
diseases<br />
24<br />
oncology<br />
31<br />
cardiometabolic<br />
diseases<br />
Research & development<br />
7
RESEARCH WITH PASSION<br />
In <strong>2012</strong>, we employed an average of 7,492 people at our R&D<br />
sites. A total of almost EUR 2.8 billion was invested in the research<br />
and development of new medicines. R&D expenditure<br />
in the business area Prescription Medicines corresponds to<br />
+ 22.5% of its net sales.<br />
Human Pharmaceuticals<br />
In Human Pharmaceuticals we are presented with a wellfilled<br />
pipeline of competitive substances, mainly in oncology,<br />
diabetes, asthma and hepatitis C. We also have a tightly scheduled<br />
series of planned launches of product innovations and<br />
thereby continued growth potential.<br />
After entering the diabetes market in 2011, we expect to enter<br />
the oncology market in 2013 and extend our respiratory portfolio.<br />
The substances from the advanced pipeline, foremost<br />
afatinib in lung cancer and tiotropium or olodaterol in respiratory<br />
diseases, have the potential to be ready for the market<br />
as early as in 2013 as well as in the next few years.<br />
8<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> summary report <strong>2012</strong>
perspectives<br />
for medical innovation<br />
Our R&D activities include both small molecules<br />
and biotherapeutics, thereby allowing<br />
us to choose the most appropriate approach<br />
for each therapeutic concept.<br />
Animal Health<br />
In Animal Health the focus is on the research and development<br />
of innovative vaccines, primarily for protecting livestock and<br />
companion animals, as well as on pharmaceutical products.<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> invested around EUR 115 million in <strong>2012</strong>,<br />
roughly 11% of total Animal Health sales, in researching and<br />
developing new products and in building up a global network<br />
of new R&D sites. An average 450 employees worked at Animal<br />
Health’s R&D sites in the USA, Germany, Mexico, China and<br />
Japan in <strong>2012</strong>.<br />
Further information:<br />
annualreport.boehringer-ingelheim.com<br />
Research & development<br />
9
OUR BUSINESS AREAS<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> divides its business activities into<br />
the areas Human Pharmaceuticals, Biopharmaceuticals and<br />
Animal Health.<br />
Human Pharmaceuticals<br />
The sales of our Human Pharmaceuticals business were<br />
EUR 13,080 million, thereby showing gratifying growth<br />
of around + 12%.<br />
Prescription Medicines<br />
The business area Prescription Medicines generated sales<br />
growth of + 13%, amounting to EUR 11,405 million. In <strong>2012</strong>,<br />
our anticoagulant pradaxa®, with sales of EUR 1.1 billion,<br />
exceeded the EUR 1 billion sales mark for the first time.<br />
The products spiriva® (EUR 3.6 billion), already established<br />
for 10 years, micardis® (EUR 1.6 billion) and combivent®<br />
(EUR 883 million) continued to record growth in sales.<br />
In addition, trajenta®, for the treatment of type 2 diabetes,<br />
has significant sales potential. We consider it very disappointing<br />
that trajenta®, a medication developed and manufactured in<br />
Germany, is precisely not available in Germany for patients<br />
with type 2 diabetes. We remain convinced that trajenta®<br />
[ spiriva® ]<br />
[ micardis® ]<br />
10<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> summary report <strong>2012</strong>
kapitelname<br />
perspectives<br />
kapitelname<br />
for better health<br />
has a distinct, patient-relevant, added benefit and we consider<br />
our position confirmed by positive therapeutic experiences in<br />
some 40 countries around the world.<br />
Consumer Health Care<br />
The business area Consumer Health Care expanded again,<br />
mainly in emerging markets and achieved worldwide sales<br />
of EUR 1,505 million, corresponding to growth of + 7.8%<br />
compared to the previous year.<br />
Biopharmaceuticals<br />
The business area Biopharmaceuticals focuses on the development<br />
and production of new, innovative biopharmaceuticals.<br />
It is comprised of the contract manufacturing business,<br />
biosimilars and the research and development of new biological<br />
active ingredients. Here, <strong>Boehringer</strong> <strong>Ingelheim</strong> achieved<br />
net sales amounting to EUR 549 million (+ 5.8%).<br />
Animal Health<br />
The products in our Animal Health business developed<br />
equally favourably, with total sales of EUR 1,062 million<br />
(+ 8.8%) led by ingelvac circoflex®, a swine vaccine, with<br />
sales of EUR 279 million (+ 8.6%).<br />
[ pradaxa® ] [ ingelvac circoflex® ]<br />
Our businesses<br />
11
BOEHRINGER INGELHEIM<br />
CORPORATION<br />
Net sales by businesses<br />
(in millions of EUR) <strong>2012</strong> 2011 Change<br />
Prescription Medicines 11,405 10,096 13.0%<br />
Consumer Health Care 1,505 1,396 7.8%<br />
Pharma Chemicals and<br />
Pharmaceuticals Production 162 178 — 9.0%<br />
Biopharmaceuticals 549 519 5.8%<br />
Animal Health 1,062 976 8.8%<br />
Net sales by region (in millions of EUR) <strong>2012</strong> 2011 Change<br />
Americas 6,905 6,087 13.4%<br />
Europe 4,194 4,037 3.9%<br />
Asia, Australasia, Africa (AAA) 3,592 3,047 17.9%<br />
Key figures (in millions of EUR) <strong>2012</strong> 2011 Change<br />
Net sales 14,691 13,171 11.5%<br />
Operating income 1,853 2,272 — 18.4%<br />
Return on net sales 12.6% 17.3%<br />
RESEARCH AND DEVELOPMENT<br />
R&D Key figures <strong>2012</strong> 2011 2010 2009 2008<br />
Expenditure in millions of EUR 2,795 2,516 2,453 2,215 2,109<br />
– as % of net sales 19.0 19.1 19.5 17.4 18.2<br />
Prescription Medicines<br />
expenditure in millions<br />
of EUR 2,563 2,372 2,306 2,100 2,016<br />
– as % of Prescription<br />
Medicines net sales 22.5 23.5 23.8 20.9 22.1<br />
Average number of employees 7,492 7,159 7,093 6,934 6,788<br />
Investments in tangible assets<br />
(without investments in infrastructure)<br />
in millions of EUR 139 112 83 125 145<br />
12<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> summary report <strong>2012</strong>
usiness year <strong>2012</strong><br />
at a glance<br />
PRESCRIPTION MEDICINES<br />
Net sales (in millions of EUR) <strong>2012</strong> 2011 Change<br />
spiriva® 3,562 3,153 13.0%<br />
micardis® 1,623 1,593 1.9%<br />
pradaxa® 1,108 629 76.2%<br />
combivent® 883 766 15.3%<br />
CONSUMER HEALTH CARE<br />
Net sales (in millions of EUR) <strong>2012</strong> 2011 Change<br />
buscopan® 212 180 17.8%<br />
dulcolax® 193 171 12.9%<br />
mucosolvan® 166 160 3.8%<br />
pharmaton® 136 137 — 0.7%<br />
ANIMAL HEALTH<br />
Net sales (in millions of EUR) <strong>2012</strong> 2011 Change<br />
ingelvac circoflex® 279 257 8.6%<br />
metacam® 99 96 3.1%<br />
ingelvac® prrs 68 57 19.3%<br />
vetmedin® 49 46 6.5%<br />
EMPLOYEES<br />
Average number of employees<br />
by region <strong>2012</strong> 2011<br />
Americas 15,208 14,300<br />
Europe 22,106 21,380<br />
Asia, Australasia, Africa (AAA) 8,914 8,414<br />
46,228 44,094<br />
At a glance<br />
13
CORPORATE BODIES<br />
Shareholders’ Committee<br />
christian boehringer<br />
Chairman of the Shareholders’ Committee<br />
christoph boehringer<br />
erich von baumbach jr.<br />
ferdinand von baumbach<br />
isabel boehringer<br />
dr mathias boehringer<br />
Advisory Board<br />
prof. dr michael hoffmann-becking<br />
Attorney at Law, Düsseldorf, Chairman of the Advisory Board<br />
egbert appel<br />
Trustee, Martin Hilti Family Trust<br />
Member of the Board and Managing Director, Hilti Foundation<br />
dr andreas kreimeyer<br />
Member of the Board of Executive Directors and<br />
Research Executive Director, BASF SE<br />
prof. dr fredmund malik (until 31.12.<strong>2012</strong>)<br />
Chairman of the Board, Malik Management Zentrum St. Gallen AG<br />
jan rinnert<br />
Vice Chairman of the Board of Management, Heraeus Holding GmbH<br />
Board of Managing Directors*<br />
prof.** dr dr andreas barner<br />
Chairman of the Board, Corporate Board Divisions Human Resources and<br />
Research, Development and Medicine<br />
hubertus von baumbach<br />
Corporate Board Division Finance<br />
prof. h.c. dr wolfram carius<br />
Corporate Board Divisions Biopharmaceuticals and Operations<br />
dr joachim hasenmaier (from 01.10.<strong>2012</strong>)<br />
Corporate Board Divisions Animal Health and Consumer Health Care<br />
allan hillgrove (from 01.01.2013)<br />
Corporate Board Division Pharma Marketing and Sales<br />
engelbert tjeenk willink (until 31.12.<strong>2012</strong>)<br />
Corporate Board Division Pharma Marketing and Sales<br />
* Change of structure of Corporate Board Divisions from 01.10.<strong>2012</strong><br />
** Republic of Austria<br />
14<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> summary report <strong>2012</strong>
corporate bodies<br />
imprint<br />
If you have any queries or comments,<br />
please contact us.<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> GmbH<br />
Binger Strasse 173<br />
55216 <strong>Ingelheim</strong><br />
Germany<br />
Telephone + 49 6132 77-0<br />
Fax + 49 6132 72-3000<br />
Contact<br />
Corporate Division Communications<br />
E-mail webmaster@boehringer-ingelheim.com<br />
Internet www.boehringer-ingelheim.com<br />
Issued by<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> GmbH<br />
Design and layout<br />
mpm · Corporate Communication Solutions<br />
www.digitalagentur-mpm.de<br />
Printed by<br />
Süddeutsche Verlagsgesellschaft, Ulm<br />
Copyright<br />
©<br />
<strong>Boehringer</strong> <strong>Ingelheim</strong> GmbH, 2013<br />
All rights reserved. No part of this Annual <strong>Report</strong> <strong>2012</strong> may be reproduced<br />
or transmitted in any form or by any means, electronic or photocopy,<br />
without permission in writing from <strong>Boehringer</strong> <strong>Ingelheim</strong> GmbH.<br />
Figures from third parties used in the annual report are based on data<br />
available at the time the financial statement was drawn up.<br />
With the CO 2<br />
emission reduction certificates we support a project that distributes water<br />
treatment units to households in rural districts in Kenya. The project improves public<br />
health significantly, inasmuch as it guarantees access to clean drinking water.<br />
Imprint<br />
15
www.boehringer-ingelheim.com<br />
annualreport.boehringer-ingelheim.com