A61K - Cooperative Patent Classification

CPC - A61K - 2013.07 - page 69
A61K 49/06 . Nuclear magnetic resonance (NMR) contrast preparations ; Magnetic resonance
imaging (MRI) contrast preparations
NOTE
-
characterised only by the (inorganic) MRI-active nucleus, e.g. 129Xe
A61K 49/08 . . characterised by the carrier
A61K 49/085 . . . { conjugated systems }
A61K 49/10 . . . Organic compounds
NOTE
-
characterised by the carrier carrying the MRI-active nucleus, e.g. inorganic
carrier]
NOTE
-
The MRI-active nucleus being complexed to a complex-forming compound
(e.g. chelating group) or being covalently linked to a molecule, which being
further covalently linked or conjugated to a carrier, e.g. polymer.
Classification being also made according to the nature of the carrier, e.g.
[Gd3+]DOTA-polymer to be classified in A61K 49/085 and in the
appropriate A61K 49/12 adequate subgroup
NOTE
-
the carrier being an organic compound, e.g. 13C-labelled molecule or
perfluorinated alkane, used as MRI in vivo probe, or a small organic
molecule, e.g. a sugar, linked to a Gd-chelate
A61K 49/101 . . . . { the carrier being a complex-forming compound able to form MRI-active
complexes with paramagnetic metals }
NOTE
-
In the A61K 49/101 subgroups, the MRI-active nucleus being
complexed to a complex-forming compound, e.g. chelating group.
Classification being made according to the nature of this
complex-forming agent, if it being either an uncommon or new
complexing agent (not the usual DTPA, DOTA, DOTP, etc...groups)
that forms the real contribution to the claimed MRI invention, or if it
being not conjugated to any further molecule, e.g. which being not
conjugated to a polymer, peptide, protein or antibody. In that latter
case, the MRI probe being e.g. a paramagnetic metal chelate]
A61K 49/103 . . . . . { the complex-forming compound being acyclic, e.g. DTPA }
A61K 49/105 . . . . . . { the metal complex being Gd-DTPA }
A61K 49/106 . . . . . { the complex-forming compound being cyclic, e.g. DOTA }
A61K 49/108 . . . . . . { the metal complex being Gd-DOTA }
A61K 49/12 . . . . Macromolecular compounds
NOTE