APPENDIXES - AHRQ Effective Health Care Program

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Table C11. Comparative effectiveness of laparoscopic versus retropubic radical prostatectomy (adapted from the systematic review by Rassweiler et al) C21 Author Population Treatment Sample ORTime Complication Reintervention Analgesics Blood Loss Transfusion Size (minutes) (%) (%) (mg) (cc) (%) Guilloneau, 2000 LRP RRP Total 220 45 PSA ng/ml 11.2 11 RRP 100 135 Not reported Not reported Not reported 850 31 Case series Gleason score 6 6 LRP 120 239 7.3 2.5 Not reported 402 10 Stage pT2 85 107 pT3a 8 7 pT3b 7 6 Salomon, 2002 46 Case series Rassweiler, 2003 47 Case series Bhayani, 2003 48 Case series Roumeguere, 2003 49 Nonrandomized clinical trial Artibani, 2003 50 Case series RRP PRP LRP Total 401 Age 65 64.6 64.1 RRP 219 197 23.8 Not reported Not reported Not reported 26.2 PSA 21 13.2 11.6 PRP 219 178 16.7 Not reported Not reported Not reported 15.9 Gleason Score 5.7 5.7 5.7 LRP 219 285 18.1 Not reported Not reported Not reported 2.9 RRP LRP LRP Early Later Age 65 64 64 pT1 5 5 1 pT2a 55 43 39 pT2b 40 73 103 pT3a 72 53 49 pT3b 21 35 22 pT4 24 10 5 Gleason score 7 6 6 PSA (ng./ml) 12 14.6 10.6 RRP LRP Age (years) 60.5 57.4 PSA (ng/ml) 8.6 6.74 Gleason score 6.13 6.06 T1a 1 0 T1c 14 21 T2a 8 11 T2b 1 1 RRP LRP Age 64 62.5 PSA (ng/ml) 11 8.6 Gleason score 5.4 5.4 RRP LRP Age 64.3 63 PSA (ng/ml) 11 16 T1b 4 1 T1c 26 20 Total 657 RRP 219 196 19.1 6.8 50.8a 1,550 55.7 LRP early 219 288 13.9 4.2 33.8 1,100 30.1 LRP late 219 218 6.1 2 30.1 800 9.6 Total 60 RRP 24 168 20.8 12.5 45 1,473 Not reported LRP 36 348 21.2 6 53c 533 Not reported Total 162 RRP 77 168 24.6 7.8 Not reported 1514 Not reported ELRP 85 288 11.8 3.5 Not reported 522 Not reported Total 121 RRP 50 105 20 4 Not reported Not reported 34 LRP 71 180 37 4.2 Not reported Not reported 63
Table C11. Comparative effectiveness of laparoscopic versus retropubic radical prostatectomy (adapted from the systematic review by Rassweiler et al) (continued) C22 Author Population Treatment Brown, 2004 51 Case series T2a 15 34 T2b 4 10 T3 1 6 Gleason score 5.7 5.8 LRP RRP Age 59 59 PSA (ng/ml) 6.4 5.6 T1a/b 0 1 T1c 47 45 T2a 13 11 T2b 0 3 Sample Size ORTime (minutes) Complication (%) Reintervention (%) Analgesics (mg) Blood Loss (cc) Transfusion (%) Total 120 RRP 60 Not reported 18.3 3.3 Not reported 1355 52 LRP 60 330 25 3.3 Not reported 317 1.7 Fornara, 2004 52 Total 64 Nonrandomized RRP 32 140 9.3 Not reported 35 550 17 clinical trial ELRP 32 220 3.1 Not reported 33 200 6 Remzi, 2005 44 Case series Keller, 2005 53,54 Nonrandomized clinical trial LRP RRP Total 121 Age (years) 59 60 RRP 41 195 Not reported 7.3 300 385 Not reported PSA (ng/ml) 8.1 6.9 LRP 39 279 Not reported 7.7 290 290 Not reported Gleason score 5.5 4.7 ELRP 41 217 Not reported 2.4 189 189 Not reported PSA >10 ng/ml Gleason score >5 Total 150 RRP 50 150 Not reported Not reported Not reported 739 4 PRP 50 86 Not reported Not reported Not reported 269 0 LRP 50 249 Not reported Not reported Not reported 322 16
Page 1 and 2: APPENDIXES
Page 3 and 4: Appendix A: Search Strategy (contin
Page 6 and 7: Appendix C: Evidence Tables and Fig
Page 8 and 9: Table C1. Disease specific mortalit
Page 10 and 11: Table C2. Biochemical progression/r
Page 12 and 13: Table C2. Biochemical progression/r
Page 14 and 15: Table C4. Incidence of distant meta
Page 16 and 17: Figure C2. Diseasespecific surviv
Page 18 and 19: Table C8. Outcomes after cryosurgic
Page 24 and 25: Table C10. Comparative effectivenes
Page 30 and 31: Table C13. Perioperative and pathol
Page 32 and 33: Figure C4. Comparative studies of t
Page 42 and 43: Table C17. Clinical outcomes after
Page 44 and 45: Table C19. Late toxicity outcomes a
Page 46 and 47: Table C20. Patient outcomes after h
Page 48 and 49: Table C21. Proton radiation for loc
Page 50 and 51: Table C23. Adjusted percentage dist
Page 52 and 53: Table C25. QOL studies of treatment
Page 60 and 61: Figure C6. Search strategy Database
Page 62 and 63: Table C27. Quality (% of maximum po
Page 64 and 65: Table C29. Geographic variations in
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Table C30. Geographic variations in
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Table C31. Association between hosp
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Table C36. Association between surg
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Table C41. Sampling sources of stud
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Table C43. Association between phys
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Figure C8. Percentage of responses
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Table C44. Variability in managemen
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Table C44. Variability in managemen
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Table C45. Association between prov
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Table C45. Association between prov
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Table C47. Distribution of urologis
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Table C49. Significant geographic d
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Figure C14. Distribution of radiati
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Figure C16. Ratio* of radiation onc
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Figure C19. Geographic variations i
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Figure C20. Incidence of prostate c
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Table C55. Incidence of localized p
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Figure C21. Percentage of patients
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Table C62. Significant variations i
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Figure C29. Length of stay in hospi
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Figure C30. Hospital charges for ra
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Table C73. Geographic differences i
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Figure C31. Mortality from prostate
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Figure C33. Difference in surgery
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Figure C35. Relative risk of surger
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Figure C37. Difference in surgery r
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Figure C39. Difference in surgery r
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Figure C41. Difference in length of
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Figure C43. Difference in rates of
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Table C76. Odds ratio and attributa
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Table C78. Odds ratio of outcomes,
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Appendix C: Evidence Tables and Fig
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Appendix D: List of Excluded Studie
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Appendix E: Sample Abstraction Form
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APPENDIXES - AHRQ Effective Health Care Program

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