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APPENDIXES - AHRQ Effective Health Care Program

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Table C32. Association between hospital volumes (radical prostatectomy) and complications (cardiac, respiratory or vascular events,<br />

the need for reoperation, bleeding, renal failure, and shock)<br />

C­80<br />

Reference<br />

Period<br />

Design<br />

Yao, 1999 123<br />

1991­1994<br />

Retrospective cohort<br />

Evidence: II­2C<br />

Quality: 0.677<br />

Hu, 2003 118<br />

1997­1998<br />

Retrospective cohort<br />

Evidence: II­2C<br />

Population<br />

101,604<br />

Medicare<br />

beneficiaries<br />

after radical<br />

prostatectomy<br />

2,292<br />

Medicare<br />

beneficiaries<br />

after radical<br />

prostatectomy<br />

Data Source<br />

Volume<br />

Definition<br />

Medicare claims<br />

data<br />

Number of<br />

procedures/time<br />

of the study<br />

Medicare claims<br />

data.<br />

Number of<br />

procedures/time<br />

of the study<br />

Outcome<br />

In­hospital<br />

complications<br />

In­hospital<br />

complications<br />

Analysis/Units<br />

Logistic<br />

regression<br />

Unit: Patient<br />

Goodness­offit:<br />

Not reported<br />

Discrimination:<br />

Not reported<br />

Multiple<br />

regression<br />

Unit: Patient<br />

Goodness­offit:<br />

Not reported<br />

Risk<br />

Adjustment<br />

Patient age,<br />

race,<br />

comorbidities;<br />

surgeon<br />

specialty,<br />

hospital<br />

teaching<br />

status<br />

Patient age,<br />

race,<br />

comorbidities,<br />

hospital type,<br />

region<br />

Volume<br />

Categories<br />

Hospital<br />

Volume<br />

141 (36/year)<br />

141 (36/year)<br />

Hospital volume<br />

(% of<br />

procedures)<br />

Low (85.2)<br />

(60 /year)<br />

Outcome<br />

Rate<br />

(%)<br />

Any<br />

complications<br />

31.3(30.8­<br />

31.9)<br />

28.7(28.2­<br />

29.3)<br />

27.8(27.2­<br />

28.3)<br />

26.3(25.8­<br />

26.9)<br />

Postoperative<br />

complications<br />

21.6<br />

16.8<br />

Adjusted<br />

Volume Effect<br />

Serious<br />

complications<br />

1.4 3(1.37; 1.48)<br />

1.25 (1.19; 1.31)<br />

1.09 (1.03; 1.15)<br />

1(reference)<br />

1.28 (1.24; 1.32)<br />

1.13 (1.08; 1.17)<br />

1.08 (1.04; 1.12)<br />

1 (reference)<br />

1 (reference)<br />

0.84(0.59; 1.19)<br />

Quality: 0.86<br />

Begg, 2002 122<br />

1992­1996<br />

Retrospective cohort<br />

Evidence: II­2C<br />

Quality: 0.63<br />

11,522<br />

Medicare<br />

beneficiaries<br />

(Parts A and<br />

B) after radical<br />

prostatectomy,<br />

6,421 with<br />

localized PC;<br />

403 hospitals<br />

SEER data<br />

base linked to<br />

Medicare claims<br />

Average<br />

number of<br />

procedures/year<br />

Postoperative<br />

complications<br />

during 30<br />

days after<br />

surgery<br />

Discrimination:<br />

Yes<br />

GEE­logistic<br />

regression<br />

Unit: Patient<br />

Goodness­offit:<br />

Not reported<br />

Discrimination:<br />

Not reported<br />

Patient age,<br />

race, stage of<br />

cancer, co<br />

morbidities;<br />

hospital ­<br />

surgeon<br />

correlations<br />

Annual Hospital<br />

Volume (%<br />

hospitals)<br />

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