Bayer CropScience - Greenbook.net
Bayer CropScience - Greenbook.net
Bayer CropScience - Greenbook.net
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
Revision Date: 09/26/2006<br />
SECTION 1. CHEMICAL PRODUCT AND COMPANY INFORMATION<br />
Product Name<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE AQUEOUS<br />
FLOWABLE<br />
MSDS Number 102000002217<br />
EPA Registration No. 264-379<br />
<strong>Bayer</strong> <strong>CropScience</strong><br />
2 T.W. Alexander Drive<br />
Research Triangle PK, NC 27709<br />
USA<br />
For MEDICAL, TRANSPORTATION or other EMERGENCY call: 1-800-334-7577 (24 hours/day)<br />
For Product Information call: 1-866-99BAYER (1-866-992-2937)<br />
SECTION 2. COMPOSITION/INFORMATION ON INGREDIENTS<br />
Hazardous Component Name CAS-No. Average % by Weight<br />
Thiodicarb 59669-26-0 34.00<br />
Dodecylbenzene sulphonate, isopropylamine salt 26264-05-1 2.20<br />
Synthetic amorphous silica 112926-00-8 1.00<br />
SECTION 3. HAZARDS IDENTIFICATION<br />
NOTE: Please refer to Section 11 for detailed toxicological information.<br />
Emergency Overview Warning! May be fatal if swallowed. Harmful if inhaled or absorbed through skin.<br />
May cause eye irritation. May cause sensitization by skin contact. Do not take<br />
internally. Avoid contact with skin, eyes and clothing. Avoid breathing spray mist.<br />
Toxic to fish. Toxic to aquatic invertebrates. Toxic to bees.<br />
Physical State<br />
Odor<br />
Appearance<br />
Routes of Exposure<br />
Immediate Effects<br />
Eye<br />
Skin<br />
suspension<br />
characteristic<br />
beige<br />
Skin Absorption, Inhalation, Eye contact, Ingestion<br />
May cause eye irritation. Avoid contact with eyes.<br />
Harmful if absorbed through skin. May cause sensitisation by skin contact. Avoid<br />
contact with skin and clothing.<br />
Page 1 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
Ingestion<br />
Inhalation<br />
Chronic or Delayed<br />
Long-Term<br />
Medical Conditions<br />
Aggravated by Exposure<br />
This product causes reversible cholinesterase inhibition. Do not take internally.<br />
May be fatal if swallowed.<br />
Harmful if inhaled. Avoid breathing spray mist.<br />
This product contains ingredients that are considered to be probable or<br />
suspected human carcinogens (see Section 11 - Chronic). This product or its<br />
components may have target organ effects.<br />
This product contains a cholinesterase inhibitor carbamate. Allow no further<br />
exposure to any cholinesterase inhibitor until full recovery is assured. Prolonged<br />
exposure and inhalation may aggravate pre-existing conditions of the respiratory<br />
system.<br />
SECTION 4. FIRST AID MEASURES<br />
General<br />
When possible, have the product container or label with you when calling a<br />
poison control center or doctor or going for treatment.<br />
Eye Rinse immediately with plenty of water, also under the eyelids, for at least 15<br />
minutes. Remove contact lenses, if present, after the first 5 minutes, then<br />
continue rinsing eye. Call a physician or poison control center immediately.<br />
Skin<br />
Ingestion<br />
Inhalation<br />
Notes to Physician<br />
Signs and<br />
Symptoms<br />
Wash off with soap and water. Take off contaminated clothing and shoes<br />
immediately. Call a physician or poison control center immediately.<br />
Do not leave victim unattended. Call a physician or poison control center<br />
immediately. Rinse out mouth and give water in small sips to drink. Never give<br />
anything by mouth to an unconscious person. DO NOT induce vomiting unless<br />
directed to do so by a physician or poison control center.<br />
Move to fresh air. If person is not breathing, call 911 or an ambulance, then give<br />
artificial respiration, preferably mouth-to-mouth if possible. Call a physician or<br />
poison control center immediately.<br />
Local:<br />
Temporary blurred vision due to contraction of the pupils (miosis) following<br />
contact with the eyes.<br />
Systemic:<br />
bradycardia<br />
low blood pressure<br />
salivation<br />
bronchial hypersecretion<br />
nausea<br />
vomiting<br />
diarrhoea<br />
sweating<br />
Page 2 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
muscular fasciculation<br />
spasm<br />
breathing difficulties<br />
respiratory paralysis<br />
somnolence<br />
coma<br />
respiratory failure<br />
hypothermia<br />
convulsions<br />
Hazards<br />
Treatment<br />
This product contains a cholinesterase inhibitor carbamate.<br />
The product inhibits cholinesterase resulting in stimulation of the central nervous<br />
system, the parasympathetic nervous system, and the somatic motor nerves. If<br />
symptoms of carbamate poisoning are present, the administration of atropine<br />
sulfate is indicated.<br />
ANTIDOTE: Administer atropine sulfate in large therapeutic doses. Repeat as<br />
necessary to the point of tolerance. In mild cases, start treatment by giving 1-2<br />
mg of atropine intravenously every 15 minutes until signs of atropinization<br />
appear (dry mouth, flushing and dilated pupils if pupils were originally pinpoint).<br />
In severe cases 2 to 4 mg should be injected intravenously every 10 minutes<br />
until fully atropinized, then intramuscularly every 30 to 60 minutes as needed to<br />
maintain the effect for at least 12 hours. Dosages for children should be<br />
appropriately reduced.<br />
Do not use oximes such as 2-PAM unless organophosphate intoxication is<br />
suspected. Do not give morphine. Watch for pulmonary edema, which may<br />
develop in serious cases of poisoning even after 24-48 hours. At first sign of<br />
pulmonary edema, the patient should be placed in an oxygen tent and treated<br />
symptomatically.<br />
SECTION 5. FIRE FIGHTING MEASURES<br />
Flash point<br />
Autoignition<br />
Temperature<br />
Fire and Explosion<br />
Hazards<br />
Suitable Extinguishing<br />
Media<br />
no data available<br />
580 °C / 1076 °F<br />
The product itself does not burn.<br />
In the event of fire the following can be released:<br />
carbon monoxide (CO)<br />
Sulphur oxides<br />
nitrogen oxides (NOx)<br />
water spray, foam, carbon dioxide (CO2), dry powder<br />
Page 3 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
Fire Fighting<br />
Instructions<br />
Keep out of smoke. Fight fire from upwind position. Cool closed containers<br />
exposed to fire with water spray. Dike area to prevent runoff and contamination<br />
of water sources. Equipment or materials involved in pesticide fires may become<br />
contaminated.<br />
Firefighters should wear NIOSH approved self-contained breathing apparatus<br />
and full protective clothing.<br />
SECTION 6. ACCIDENTAL RELEASE MEASURES<br />
Personal Precautions<br />
Methods for Cleaning Up<br />
Additional Advice<br />
Keep unauthorized people away. Isolate hazard area. Avoid contact with spilled<br />
product or contaminated surfaces.<br />
Recover the product by pumping, suction or absorption using a dry and inert<br />
absorbent clay. Take up with absorbent material (e.g. sand, diatomaceous earth<br />
or a proprietary absorbent material). Pick up and fill the product into a tightly<br />
closed container. When picked up, treat material as prescribed in Ch. 13.<br />
"Disposal considerations".<br />
Contact <strong>Bayer</strong> for further assistance if necessary. Use personal protective<br />
equipment. Do not allow product to enter streams, sewers or other waterways.<br />
SECTION 7. HANDLING AND STORAGE<br />
Handling Procedures<br />
Storing Procedures<br />
Smoking, eating and drinking should be prohibited in the application area.<br />
Keep out of the reach of children.<br />
Store in a cool, dry place and in such a manner as to prevent cross<br />
contamination with other pesticides, fertilizers, food, and feed. Store in original<br />
container and out of the reach of children, preferably in a locked storage area.<br />
Work/Hygienic<br />
Procedures<br />
Wash hands thoroughly with soap and water after handling and before eating,<br />
drinking, chewing gum, using tobacco, using the toilet or applying cosmetics.<br />
Take off contaminated clothing and shoes immediately. Then wash thoroughly<br />
and put on clean clothing.<br />
Remove Personal Protective Equipment (PPE) immediately after handling this<br />
product. Before removing gloves clean them with soap and water. As soon as<br />
practical, wash thoroughly and change into clean clothing.<br />
Min/Max Storage<br />
Temperatures<br />
Do not transport or store above 46 °C / 115 °F<br />
Page 4 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
SECTION 8. EXPOSURE CONTROLS / PERSONAL PROTECTION<br />
General Protection<br />
Cholinesterase activity of the worker should be supervised.<br />
Train employees in safe use of the product. Follow all label instructions.<br />
Follow manufacturer's instructions for cleaning/maintaining PPE. If no such<br />
instructions for washables, use detergent and warm/tepid water. Keep and wash<br />
PPE separately from other laundry.<br />
Engineering Controls<br />
Eye/Face Protection<br />
Hand Protection<br />
Body Protection<br />
Respiratory Protection<br />
Maintain exposure levels below the exposure limit through the use of general<br />
and local exhaust ventilation.<br />
tightly fitting safety goggles<br />
Chemical resistant nitrile rubber gloves<br />
Wear long-sleeved shirt and long pants and shoes plus socks.<br />
When respirators are required, select NIOSH approved equipment based on<br />
actual or potential airborne concentrations and in accordance with the<br />
appropriate regulatory standards and/or Industry recommendations.<br />
Exposure Limits<br />
1,2-Propanediol 57-55-6 WEEL TWA 10 mg/m3<br />
Form of Exposure<br />
Aerosol.<br />
Synthetic amorphous 112926-00-8 ACGIH TWA 10 mg/m3<br />
silica<br />
OSHA Z1A TWA 6 mg/m3<br />
NIOSH REL 6 mg/m3<br />
OSHA Z1 PEL 5 mg/m3<br />
Form of Exposure<br />
Respirable fraction.<br />
OSHA Z1 PEL 15 mg/m3<br />
Form of Exposure<br />
Total dust.<br />
Z3 TWA 15 millions of particles per<br />
cubic foot of air<br />
Form of Exposure<br />
Respirable fraction.<br />
Z3 TWA 50 millions of particles per<br />
cubic foot of air<br />
Form of Exposure<br />
Total dust.<br />
Z3 TWA 5 mg/m3<br />
Form of Exposure<br />
Respirable fraction.<br />
Z3 TWA 15 mg/m3<br />
Form of Exposure<br />
Total dust.<br />
US CA OEL TWA PEL 5 mg/m3<br />
Form of Exposure<br />
Respirable fraction.<br />
US CA OEL TWA PEL 10 mg/m3<br />
Page 5 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
Form of Exposure<br />
Total dust.<br />
US CA OEL TWA PEL 5 mg/m3<br />
Form of Exposure<br />
Respirable fraction.<br />
US CA OEL TWA PEL 10 mg/m3<br />
Form of Exposure<br />
Total dust.<br />
US CA OEL TWA PEL 5 mg/m3<br />
Form of Exposure<br />
Respirable fraction.<br />
US CA OEL TWA PEL 10 mg/m3<br />
Form of Exposure<br />
Total dust.<br />
Z3 TWA 20 millions of particles per<br />
cubic foot of air<br />
Z3 TWA 0.8 mg/m3<br />
Remarks<br />
The value is calculated from<br />
a specified equation using a<br />
value of 100%. Lower values<br />
of % will give higher<br />
exposure limits. See<br />
regulation for specific<br />
equation.<br />
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES<br />
Appearance<br />
Physical State<br />
Odor<br />
beige<br />
suspension<br />
characteristic<br />
pH 4.0 - 6.5 (100 %)<br />
Density ca. 1.14 g/cm³ at 20 °C<br />
Boiling Point 100 °C / 212 °F<br />
Melting / Freezing Point -5 °C / 23 °F<br />
Water solubility<br />
Partition coefficient (noctanol/water)<br />
Viscosity<br />
dispersible<br />
log Pow: 1.62<br />
700 - 1,000 mPa.s<br />
SECTION 10. STABILITY AND REACTIVITY<br />
Chemical Stability<br />
Stable under recommended storage conditions.<br />
Page 6 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
Conditions to Avoid<br />
Incompatibility<br />
Hazardous<br />
Decomposition Products<br />
Heat, flames and sparks.<br />
bases<br />
brass<br />
cupric chloride<br />
iron chlorides<br />
metal salts<br />
mineral acids<br />
rust<br />
Thermal decomposition can lead to release of:<br />
Carbon monoxide<br />
Sulphur oxides<br />
nitrogen oxides (NOx)<br />
SECTION 11. TOXICOLOGICAL INFORMATION<br />
Only acute toxicity studies have been performed on this product as formulated. The non-acute information<br />
pertains to the active ingredient, thiodicarb technical.<br />
Acute Oral Toxicity<br />
male rat: LD50: 357 mg/kg<br />
female rat: LD50: > 330 - < 558 mg/kg<br />
Acute Dermal Toxicity<br />
Acute Inhalation Toxicity<br />
male/female rabbit: LD50: > 2,000 mg/kg<br />
male/female rat: LC50: 1.51 mg/l<br />
Exposure time: 4 h<br />
Determined in the form of liquid aerosol.<br />
male/female rat: LC50: > 2.53 mg/l<br />
Exposure time: 1 h<br />
Determined in the form of liquid aerosol.<br />
Skin Irritation<br />
Eye Irritation<br />
Sensitization<br />
Chronic Toxicity<br />
rabbit: Slight irritation.<br />
rabbit: Slight irritation.<br />
guinea pig: sensitizing<br />
Thiodicarb caused cholinesterase inhibition in a chronic toxicity study in dogs. In<br />
rats and mice, the principal organs affected from long-term dietary exposure to<br />
thiodicarb included the liver, spleen and testis.<br />
Assessment Carcinogenicity<br />
Thiodicarb has been classified by EPA as a Group B2 (probable human carcinogen) based on its<br />
oncogenic potential at high dose levels in mice (liver tumors) and rats (benign testicular tumors). At low<br />
doses the product would not be expected to cause these tumors in humans.<br />
Page 7 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
ACGIH<br />
None.<br />
NTP<br />
None.<br />
IARC<br />
OSHA<br />
None.<br />
Reproductive &<br />
Developmental Toxicity<br />
REPRODUCTION: Thiodicarb is not a primary reproductive toxicant based on a<br />
two-generation study in rats. Reproductive effects (e.g., decreased viability)<br />
were considered secondary to maternal toxicity.<br />
DEVELOPMENTAL TOXICITY: Thiodicarb is not teratogenic based on<br />
developmental toxicity studies in rats, mice and rabbits. Developmental effects<br />
(e.g., delayed ossifications) were observed in rats and were considered<br />
secondary to maternal toxicity.<br />
Neurotoxicity<br />
Mutagenicity<br />
Thiodicarb caused transient neurobehavioral effects related to cholinergic toxicity<br />
in acute and/or subchronic neurotoxicity screening studies in rats. There were<br />
no neuropathological changes observed in either study. Thiodicarb did not<br />
cause neurotoxic effects in a delayed neurotoxicity study with atropinepretreated<br />
hens.<br />
The overall weight of evidence indicates thiodicarb is non-genotoxic or nonmutagenic<br />
based on a battery of in vitro and in vivo mutagenicity studies.<br />
SECTION 12. ECOLOGICAL INFORMATION<br />
Toxicity to Fish<br />
Rainbow trout (Oncorhynchus mykiss)<br />
LC50: 14.4 mg/l<br />
Exposure time: 96 h<br />
Toxicity to Aquatic Plants Selenastrum capricornutum<br />
EC50: > 18 mg/l<br />
Exposure time: 96 h<br />
The value mentioned relates to the active ingredient.<br />
Acute Toxicity to Aquatic<br />
Invertebrates<br />
Water flea (Daphnia magna)<br />
EC50: 0.29 mg/l<br />
Exposure time: 48 h<br />
Bioaccumulation Bluegill sunfish BCF: 6.3<br />
Information refers to the main component.<br />
Page 8 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
Environmental<br />
Precautions<br />
For terrestrial uses, do not apply directly to water, or to areas where surface<br />
water is present, or to intertidal areas below mean high water mark. Do not apply<br />
when weather conditions favor runoff or drift. Drift or run-off from treated areas<br />
may be hazardous to aquatic organisms in neighboring areas. Do not<br />
contaminate surface or ground water by cleaning equipment or disposal of<br />
wastes, including equipment wash water. Apply this product as specified on the<br />
label.<br />
Do not apply this product or allow it to drift to blooming crops or weeds if bees<br />
are visiting the treatment area.<br />
SECTION 13. DISPOSAL CONSIDERATIONS<br />
General Disposal<br />
Guidance<br />
Container Disposal<br />
RCRA Classification<br />
Do not contaminate water, food, or feed by disposal. Pesticide, spray mixture or<br />
rinse water that cannot be used according to label instructions may be disposed<br />
of on site or at an approved waste disposal facility.<br />
Do not re-use empty containers. Triple rinse containers. Puncture container to<br />
avoid re-use. Dispose of empty container in a sanitary landfill or by incineration,<br />
or, if allowed by State/Provincial and local authorities, by burning. If burned, stay<br />
out of smoke.<br />
The RCRA Classifications may be on the individual component(s) and not<br />
necessarily on the product as a whole.<br />
59669-26-0 Thiodicarb<br />
US. EPA Resource Conservation and Recovery Act (RCRA) Composite List of Hazardous<br />
Wastes and Appendix VIII Hazardous Constituents (40 CFR 261): U410<br />
59669-26-0 Thiodicarb<br />
US. EPA Resource Conservation and Recovery Act (RCRA) U List of Hazardous Wastes (40<br />
CFR 261.33(f) and 40 CFR 302 [CERCLA]): U410<br />
SECTION 14. TRANSPORT INFORMATION<br />
DOT CLASSIFICATION:<br />
Carbamate Pesticides, Liquid, Toxic // 6.1 // UN2992 // PG III<br />
IMDG CLASSIFICATION:<br />
Carbamate Pesticides, Liquid, Toxic(Thiodicarb) // 6.1 // UN2992 // PG III<br />
FREIGHT CLASSIFICATION:<br />
Insecticides or Fungicides, N.O.I.; poison, other than gases that are poisonous by inhalation<br />
Page 9 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
SECTION 15. REGULATORY INFORMATION<br />
EPA Registration No. 264-379<br />
US Federal Regulations<br />
TSCA list<br />
Dodecylbenzene sulphonate, isopropylamine 26264-05-1<br />
salt<br />
US. Toxic Substances Control Act (TSCA) Section 12(b) Export Notification (40 CFR 707, Subpt D)<br />
None.<br />
SARA Title III - Section 302 - Notification and Information<br />
None.<br />
SARA Title III - Section 313 - Toxic Chemical Release Reporting<br />
Thiodicarb 59669-26-0 1.0%<br />
US States Regulatory Reporting<br />
CA Prop65<br />
This product contains a chemical known to the State of California to cause cancer.<br />
Thiodicarb 59669-26-0<br />
This product does not contain any substances known to the State of California to cause reproductive<br />
harm.<br />
US State Right-To-Know Ingredients<br />
Thiodicarb 59669-26-0 NJ<br />
Synthetic amorphous silica 112926-00-8 CA, IL, MN, RI<br />
Canadian Regulations<br />
Canadian Domestic Substance List<br />
Dodecylbenzene sulphonate, isopropylamine 26264-05-1<br />
salt<br />
Synthetic amorphous silica 112926-00-8<br />
Environmental<br />
CERCLA<br />
Thiodicarb 59669-26-0 1 lbs<br />
Clean Water Section 307 Priority Pollutants<br />
None.<br />
Safe Drinking Water Act Maximum Contaminant Levels<br />
None.<br />
International Regulations<br />
European Inventory of Existing Commercial Substances (EINECS)<br />
Thiodicarb 59669-26-0<br />
Dodecylbenzene sulphonate, isopropylamine 26264-05-1<br />
salt<br />
Page 10 of 11
<strong>Bayer</strong> <strong>CropScience</strong><br />
Material Safety Data Sheet<br />
LARVIN® BRAND 3.2 THIODICARB INSECTICIDE/OVICIDE<br />
AQUEOUS FLOWABLE<br />
MSDS Number: 102000002217<br />
MSDS Version 2.0<br />
SECTION 16. OTHER INFORMATION<br />
NFPA 704 (National Fire Protection Association):<br />
Health - 2 Flammability - 1 Reactivity - 1 Others - none<br />
0 = minimal hazard, 1 = slight hazard, 2 = moderate hazard, 3 = severe hazard, 4 = extreme hazard<br />
Reason to Revise: Re-numbered due to system update.<br />
Revision Date: 09/26/2006<br />
This information is provided in good faith but without express or implied warranty. The customer assumes all<br />
responsibility for safety and use not in accordance with label instructions. The product names are registered<br />
trademarks of <strong>Bayer</strong>.<br />
Page 11 of 11
Change language