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Bottom-up and top-down approaches in Computational Neuroscience

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Model connectivity<br />

overall connection probability<br />

0.2<br />

0.1<br />

number of synapses per neuron (norm.)<br />

1.0<br />

0.5<br />

↑<br />

0.0<br />

10 3 10 4 10 5<br />

network size (number of neurons)<br />

0.0<br />

10 3 10 4 10 5<br />

network size (number of neurons)<br />

appropriate model size to:<br />

prevent underestimation of local connectivity<br />

represent most local synapses with<strong>in</strong> the network<br />

September 13th 2011, GRS Markus Diesmann Folie 20

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