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Protein Pegylation and Manufacturing - celares Gmbh

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<strong>Protein</strong> PEGylation<br />

<strong>and</strong> <strong>Manufacturing</strong><br />

Celares GmbH <strong>and</strong> Scil <strong>Protein</strong>s<br />

GmbH offer a one-stop-solution for<br />

supply <strong>and</strong> manufacturing of<br />

PEGylated <strong>Protein</strong>s<br />

Integrated solutions for the development of pharmaceutical proteins<br />

Contact:<br />

<strong>celares</strong> GmbH, Robert-Roessle-Str. 10, 13125 Berlin, Germany,<br />

tel. +49(0)30/94 89-23 50, fax: +49(0)30/94 89-23 51,<br />

Dr. Frank Leenders, email: pegylation@<strong>celares</strong>.com, www.<strong>celares</strong>.com


CelaSYS – New St<strong>and</strong>ards for PEGylation<br />

<strong>Protein</strong> PEGylation <strong>and</strong> <strong>Manufacturing</strong><br />

by <strong>celares</strong> GmbH <strong>and</strong> Scil <strong>Protein</strong>s GmbH<br />

PEGylation of proteins offers a potent tool to increase potency, half life <strong>and</strong> solubility of<br />

proteins. Celares GmbH <strong>and</strong> Scil <strong>Protein</strong>s GmbH offer a one-stop-solution for supply<br />

<strong>and</strong> manufacturing of PEGylated proteins.<br />

Our Service<br />

� PEGylation of <strong>Protein</strong>s<br />

� Supply of PEGylated protein variants for validation <strong>and</strong> lead c<strong>and</strong>idate optimization<br />

� Process development for the production of PEGylated proteins<br />

� Production of PEGylated proteins for clinical studies <strong>and</strong> market supply<br />

For research <strong>and</strong> development of therapeutics<br />

� <strong>Protein</strong> design adapted to PEGylation<br />

� Small scale protein production<br />

� PEGylation screening <strong>and</strong> characterisation of conjugates<br />

� Production of PEGylated proteins<br />

For clinical studies <strong>and</strong> market supply<br />

� Development of complete production processes for PEGylated proteins, including<br />

cell lines, upstream <strong>and</strong> downstream processes <strong>and</strong> product sanalyses<br />

� Pilot production for toxicological studies<br />

� GMP production of PEGylated proteins for clinical trials <strong>and</strong> market supply<br />

References

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