Danny A. Basso, CNMT, NCT, FSNMTS Cardiac Imaging of Augusta ...

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Intracoronary APV Ratio 3.5 3.0 2.5 2.0 1.5 1.0 400-mcg Lexiscan (n=8) 400-mcg Lexiscan + aminophylline (n=4) Time to >2.0-fold above baseline: 30 sec Duration at ≥2.5-fold above baseline: 2.3 min 0 2 4 6 8 10 » Activation of the A 2A adenosine receptor by Lexiscan produces coronary vasodilation and increases coronary blood flow (CBF) 2 » Lexiscan causes a rapid increase in CBF that is sustained for a short duration 2 Time, min The effects of Lexiscan (400-mcg,
Relative Blood Flow of Stress Modalities Blood Flow (ml/min/g)
Page 1: Danny A. Basso, CNMT, NCT, FSNMTS C
Page 4: Incremental vs Submaximal Exercise
Page 8 and 9: Adenosine Dipyridamole blocks re-up
Page 10 and 11: • The ideal pharmacologic stresso
Page 12 and 13: • 2 nd or 3 rd degree AV block
Page 14 and 15: Conclusion: In this pilot safety st
Page 16 and 17: • No calculating doses • No dra
Page 19 and 20: Gaemperli O, et al. J Am Coll Cardi
Page 21 and 22: • Some common prescription drugs
Page 23 and 24: • 5ml of Lexiscan(0.4 mg regadeno
Page 25: Δ APV (cm/sec) 70 50 30 10 Regaden
Page 32 and 33: SOB HA Nausea Any Iskandrian et al,
Page 34 and 35: *Compared to open label adenosine t
Page 36 and 37: • Conclusion: This phase 3 trial
Page 38 and 39: • 62 year old male • Hx of CAD
Page 40: • Starting HR 59bpm BP-144/84 •
Page 46: • A selective A 2A adenosine rece

Danny A. Basso, CNMT, NCT, FSNMTS Cardiac Imaging of Augusta ...

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