Quick Disconnect Couplings for - Colder Products Company

Quick Disconnect Couplings for

2 

Colder Products Company 

Colder Products Company is the worldwide leader in the design and manufacture of 

quick disconnect couplings that allow flexible tubing to be quickly and easily 

connected and disconnected. These specially-engineered solutions lend flexibility, 

control and safety to a broad range of 

applications. Colder’s connections make 

systems cleaner, drier and safer, while 

adding new value and functionality to 

smaller-scale applications. 

Colder supports its product lines and 

literature with an interactive Web site. 

The site showcases new product 

innovations and technologies, and 

provides easy, immediate access to 

product and industry information, 

application tools and more. 

Visit www.colder.com for: 

■ Information and literature on Colder product lines and technologies 

• Bioprocessing 

• Medical Device & Equipment 

• High Purity & Chemical Management 

• Industrial 

• IdentiQuik Technology 

• Food, Beverage & Water 

■ Validation reports 

Medical Device Chemical 

Management 

■ Steam-Thru ® movies 

■ Downloadable CAD drawings 

■ Online tools and selector guides 

■ Information on custom applications 

■ Direct connections to Colder engineers 

On-line Catalogs and Literature 

Industrial Smart Technology 

Food, Beverage & Water 

Call toll free 1-800-444-2474 or visit us at www.colder.com 

Copyright © 2004-2006 by Colder Products Company. All rights reserved. Colder Products Company, Colder Products and CPC are registered trademarks with the US Patent & Trademark Office.

Advantages of Disposable Systems 

Increase Productivity 

The reliability of single-use systems result in increased productivity through the 

reduction of system downtime associated with cleaning and cleaning validation. 

Reducing downtime of key processes allows manufacturers to increase output while 

also decreasing time to market. 

Add Flexibility 

Flexibility is an equally important factor as processors strive to increase 

productivity and prepare facilities for new drugs. Unlike hard-plumbed piping 

systems, disposable systems can be easily modified for alternative media handling. 

For instance, the implementation of single-use technologies can increase 

production capacity at an existing facility where traditional fixed systems would 

normally require costly facility expansion. 

Minimize Risk 

Reducing risks continues to be a fundamental concern in the bioprocessing 

industry. Media contamination can lead to product quality issues. Subsequently, 

expensive reprocessing activities are often required to prevent the loss of a valuable 

batch of media. Contamination risk becomes an even larger concern as companies 

are now conducting more multi-product manufacturing. In addition to having a 

negative effect on operational efficiency, cross-contamination can negatively 

impact a company’s reputation. The integration of single-use systems can help 

minimize this possibility. 

Reduce Cost 

Cost savings include the reduced chemical and utility expenses of cleaning and 

labor. Capital savings on new construction can be attributed to disposable systems 

because upfront capital requirements are reduced due to lower equipment and 

floor space needs. Finally, existing facilities can reduce WFI requirements 

associated with traditional systems. 

Reliable, flexible, compatible, sterile. 

Colder – first choice in connections. 


Copyright © 2004-2006 by Colder Products Company. All rights reserved. Colder Products Company, Colder Products and CPC are registered trademarks with the US Patent & Trademark Office. 

3

4 

How to Integrate Disposables into 

your Stainless Steel World 

Today’s biopharm manufacturers are pressured to improve production yields, decrease 

time to market and increase multi-product manufacturing within single facilities. In 

response they are increasingly incorporating disposable connections into their 

production processes. Colder Products Company’s Steam-Thru ® and SaniQuik 

Connections provide innovative solutions for integrating disposable systems with 

manufacturers’ existing processing equipment. 

Steam-Thru ® Connections 

The Steam-Thru Connection’s patented three-port design allows steam to pass 

directly through the lower ports to “steam on” to stainless equipment. After the SIP 

cycle is completed, the connector’s valve is actuated, creating a sterile flow path to 

single-use systems. Media can then be safely transferred without the cleaning and 

validation concerns associated with reusable components. 

The new Steam-Thru II builds upon this proven technology by offering the flexibility 

of “steam on” and “steam off” functionality. The innovative design allows the valve 

to be returned to the steam position enabling a second SIP cycle following media 

transfer. The “steam off” disconnection of disposable systems minimizes crosscontamination 

risks associated with reusable components. 

Steam-Thru Benefits 

• Provides a sterile connection between hard-plumbed and 

disposable systems 

• Sterilize prior to removal from equipment 

(Steam-Thru II) 

• Eliminates need for laminar flow hoods 

• Disposable design saves time and money by eliminating 

unnecessary cleaning procedures 

• Reduces cleaning and validation issues associated with reusable components 

• Ideal for use in feeding, cell harvesting and sampling applications 


SaniQuik Connections 

SaniQuik connections provide a quick and easy link between stainless equipment and 

single-use bag systems, tube sets or sampling systems. SaniQuik’s integral sanitary 

termination attaches directly to hard-plumbed systems with a sanitary gasket and 

tri-clover clamp. Once attached to equipment the connection’s integral 

coupling adaptor provides the interface to disposable systems which 

incorporate widely accepted Colder MPC or MPX couplings. SaniQuik 

not only decreases connection time it also allows tube sets to be 

specified with disposable plastic couplings in place of the more 

expensive stainless steel sanitary fittings. 

Sanitary Series Couplings 

SaniQuik Benefits 

• Provides a quick and easy link between 

disposable systems and existing stainless steel 

processing equipment 

• Connects to hard-plumbed systems with 

standard sanitary gasket and tri-clover clamp 

• Mates with Colder’s MPC and MPX disposable 

couplings 

• Increases operational efficiency 

• Withstands multiple sterilization cycles 

• Reduces sanitary gasket replacements 

• Ideal for use in feeding, cell harvesting, and 

sampling applications 

In addition to the SaniQuik, Colder offers the Sanitary Series 

which allows a quick and easy connection between the hard 

plumbed and disposable systems. The Sanitary Series is a costeffective 

plastic disposable solution for connecting to existing 

sanitary terminations. 



5

6 

Bioprocessing Couplings 

PAGE10 

PAGE12 

PAGE14 

PAGE16 

Table of Contents 

Couplings connected and shown actual size (approximate). 

For additional terminations and configurations, see product pages. 

Cv values are expressed in English based on gpm and psi and in metric (shown in parentheses) based on lpm and bar. 

Steam-Thru ® 

Connections 

STC2020200 

MPC Series 

MC22004T03M & MPC17006T03 

MPX Series 

MPX22839M & MPX17839 


SQCX222424M 

Straight 

Thru 

Single 

Shutoff 

Double 

Shutoff 

Non-Spill 

Material: Medical-Grade Polysulfone 

Tubing Range: 3/8" & 1/2" ID (9.5mm & 12.7mm) 

Sanitary Size: 3/4" mini and 1-1/2" maxi 

Feature: Disposable; innovative design 

Cv~8.0 (115.00) max 

Material: Medical-Grade ABS, 

Polycarbonate and Polysulfone 

Tubing Range: 1/4" & 3/8" ID (6.4mm & 9.5mm) 

Feature: Reusable coupling 

Cv~5.5 (79.25) max 

Material: Medical-Grade Polycarbonate 

and Polysulfone 

Tubing Range: 3/8" and 1/2" ID 

(9.5mm and 12.7mm) 

Feature: Reusable coupling with higher flow 

Cv~14.2 (204.60) max 

Material: 316 Stainless 

Tubing Range: 1/4" to 1/2" ID 

(6.4mm and 12.7mm) 

Sanitary Size: 3/4" mini and 1-1/2" maxi 

Feature: Transition from stainless sanitaries 

to disposable MPC/MPX bodies 

Cv~14.2 (204.60) max 



Bioprocessing Couplings 

PAGE18 

Table of Contents (continued) 

Straight 

Thru 

Single 

Shutoff 



Double 

Shutoff 


MPU Series 

MPU171239 & MPU221239M 


Tubing Range: 3/4" ID (19.0mm) 

Feature: Large flow capacity 

Cv~20.9 (301.14) max 

Non-Spill 

PAGE17 Sanitary Series 

MPC22006T39M & MPC3301239 


Tubing Range: 1/4" & 3/8" ID for insert 

(6.4mm & 9.5mm) 

Sanitary Size: 3/4" mini & 1" maxi 

(19.0mm & 25.4mm) 

Feature: Attaches directly to sanitary 

hardware assemblies 

Cv~5.5 (79.25) max with MPC 

inserts and 14.2 (204.60) max 

with MPX inserts 

PAGE19 

HFC39 Series 

HFC22639M & HFCD17839M 


Tubing Range: 1/4", 3/8" & 1/2" ID 

(6.4mm, 9.5mm & 12.7mm) 

Feature: Automatic shutoff valves 

Cv~1.6 (23.05) max 

Cv~1.5 (21.61) max 



7

8 

High Purity ChemQuik ® and DrumQuik ® Series 

PAGE20 

PAGE21 

Technical Information 

PAGE22 

Custom Solutions 

PAGE23 

Table of Contents (continued) 




CQG06 Series 

CQGD06200108 & CQGD06100108 

DrumQuik ® 

MODULAR Series 

(shown with shipping plugs installed) 

DrumQuik ® photos not to scale 

Sterilization Methods and Guide 

Special Application Capabilities 

Straight 

Thru 

Single 

Shutoff 

Wetted Material: Natural, Virgin Polypropylene 

Tubing Range: 3/8", 1/2", & 3/4" OD 

(9.5mm, 12.7mm & 19.0mm) 

Feature: Pressure-balanced design 

Cv~2.7 (38.90) max 

Wetted Material: Virgin Polypropylene or PTFE 

(shown with couplings installed) 


Double 

Shutoff 

Non-Spill 


Steam-Thru ® Connections 

Ease The Transition 

Colder Products Company advances steam-in-place technology with the 

introduction of Steam-Thru ® Connections. The innovative design allows a quick 

and easy sterile connection between biopharmaceutical processing equipment and 

disposable bag and tube assemblies. 

The Steam-Thru Connection’s patented three-port design allows steam to pass 

directly through the lower ports to “steam on” to stainless equipment. After the 

SIP cycle is completed, the connector’s valve is actuated, creating a sterile flow 

path to single-use systems. Media can then be safely transferred without the 

cleaning and validation concerns associated with reusable components. 

The new Steam-Thru II builds upon this proven technology by offering the 

flexibility of “steam on” and “steam off” functionality. The innovative design 

allows the valve to be returned to the steam position enabling a second SIP cycle 

following media transfer. The “steam off” disconnection of disposable systems 

minimizes cross-contamination risks associated with reusable components. 

Today’s biopharmaceutical manufacturers are meeting the challenges of increased 

productivity, reduced costs and decreased time to market with the help of Colder’s 

Steam-Thru Connections. 

FEATURES BENEFITS 

Innovative three-port design Allows a true steam-through SIP process 

Eliminates “dead legs” where bacteria can grow 

Eliminates the need for laminar flow hoods 

Patented valve design Creates “steam-on” sterile connection 

Allows “steam-off” sterile disconnection 

Permits high media flow rate 

Thumb latch/Tear-away sleeve Provides visual indicator of process stage 

Secures valve position 

Industry standard terminations Speeds connection to the process equipment 

Connects to popular sizes of flexible tubing 

Medical-grade polysulfone Meets USP Class VI biocompatibility 

Animal-free materials 

Compatible with standard sterilization methods 

Single-use design Saves time and money by eliminating unnecessary 

cleaning procedures 

Reduces cleaning and validation issues associated 

with reusable components 



59

10 

Steam-Thru ® Process 

Steam Position Flow Position 

Tear-Away 

Sleeve 

Steam-Thru ® II 

Process 

*An audible “click” and the visual indicator of the raised thumb latch 

provide assurance that the valve is locked in the flow or steam position. 

Steam On Position Flow Position 

Steam Off Position 

To Steam Trap 

Steam 

Flow 

To Steam Trap 

Process 

Equipment 

Steam flows from the process equipment 

through the Steam-Thru II creating a 

“steam on” sterile connection. 

Transition to Flow 

Once the “steam on” 

cycle is complete and 

the steam trap has been 

closed, simply press the 

thumb latch to allow the 

valve to be moved down 

to the flow position. 

Steam 

Flow 

Process 

Equipment 

Steam flows from the process equipment 

through the Steam-Thru to sterilize the 

connection. With the tear-away sleeve in 

place, the transfer of fluid to or from the 

bioreactor is prevented. 

Single-Use 

Bag or Tubing 

Assembly 

From 

Media Flow OR 

Once the valve is locked in the flow 

position a sterile flow path has been 

created allowing media transfer. 

To 

Single-Use 

Bag or Tubing 

Assembly 

Thumb latch 

recessed during 

valve transition 

Media Flow 

Process 

Equipment 

Transition to Steam 

Process 

Equipment 

When the tear-away sleeve is removed, and 

the Steam-Thru is actuated, the connection 

to the steam trap is disabled and a sterile 

flow path is established between the process 

equipment and the disposable system. 

To Steam Trap 

Steam 

Flow 

Once the valve is locked in the steam 

position, complete a second SIP cycle to 

“steam off” the connection. 

Once media transfer 

is complete, simply 

press the thumb 

latch to allow the 

valve to be moved 

back up to the 

steam position. 

Process 

Equipment 



From 

To 

OR

Steam-Thru ® Specifications 

Pressure: 

Steam position: Up to 30 psi, 2.07 bar (Steam-Thru); 

35 psi, 2.41 bar (Steam-Thru II) 

Flow position: Vacuum to 20 psi, 1.38 bar 

Temperature: 

Steam position: Up to 130° C (266° F) for 60 minutes 

(Steam-Thru); Up to 135° C (275° F) for 60 minutes 


Flow position: 4° C to 40° C (39° F to 104° F) 

Typical Flow Rate: 

Cv = 3.3 - 3.4 (Steam-Thru 3/8" hose barb); 

Cv = 4.1 - 4.5 (Steam-Thru 1/2" hose barb); 

Cv = 5.2 - 8.0 (Steam-Thru II 1/2" hose barb) 

Materials: 

Connection: Polysulfone, USP Class VI 

Seals: Silicone (clear), platinum-cured, USP Class VI 

Tear-away sleeve: Polyethylene or polycarbonate 

(Steam-Thru only) 

Steam-Thru Configurations 

Polysulfone with Polyethylene Sleeve 

Steam-Thru II Configurations 

Sterilization: 

Gamma: Up to 50 kGy gamma irradiation 

Autoclave: At 128° C (265° F) for 30 minutes, up to 

two cycles (applies only to part numbers STC1700500- 

STC1700800) 

SIP process: Up to 130° C (266° F) for 60 minutes 

(Steam-Thru); Up to 135° C (275° F) for 60 minutes 


Tubing sizes: 3/8" and 1/2" ID (Steam-Thru) 

9.5mm and 12.7mm ID 

1/2" ID (Steam-Thru II) 

12.7mm ID 

PART NO. TERMINATIONS A B C D E 

STC1700000 3/4" x 3/4" sanitary x 1/2” HB 1.20 (30.5) 2.00 (50.8) 0.89 (22.6) 5.09 (129.3) 4.44 (112.8) 

STC1700100 3/4”x 3/4” sanitary x 3/8” HB 1.20 (30.5) 2.00 (50.8) 0.60 (15.2) 4.80 (121.9) 4.15 (105.4) 

STC1700200 3/4" x 1-1/2" sanitary x 1/2” HB 1.20 (30.5) 2.00 (50.8) 0.89 (22.6) 5.09 (129.3) 4.44 (112.8) 

STC1700300 3/4”x 1-1/2” sanitary x 3/8” HB 1.20 (30.5) 2.00 (50.8) 0.60 (15.2) 4.80 (121.9) 4.15 (105.4) 

Polysulfone with Autoclavable Polycarbonate Sleeve 

All measurements are in inches (millimeters). 


STC1700500 3/4" x 3/4" sanitary x 1/2” HB 1.20 (30.5) 2.00 (50.8) 0.89 (22.6) 5.09 (129.3) 4.44 (112.8) 

STC1700600 3/4”x 3/4” sanitary x 3/8” HB 1.20 (30.5) 2.00 (50.8) 0.60 (15.2) 4.80 (121.9) 4.15 (105.4) 

STC1700700 3/4" x 1-1/2" sanitary x 1/2” HB 1.20 (30.5) 2.00 (50.8) 0.89 (22.6) 5.09 (129.3) 4.44 (112.8) 

STC1700800 3/4”x 1-1/2” sanitary x 3/8” HB 1.20 (30.5) 2.00 (50.8) 0.60 (15.2) 4.80 (121.9) 4.15 (105.4) 

All measurements are in inches (millimeters). 


STC2020000 3/4" x 3/4" sanitary x 1/2" HB 1.42 (36.1) 2.40 (61.0) .89 (22.6) 6.84 (173.7) 5.93 (150.6) 

STC2020200 3/4" x 1-1/2" sanitary x 1/2" HB 1.42 (36.1) 2.40 (61.0) .89 (22.6) 6.85 (173.7) 5.93 (150.6) 

A 

A 

C 

E 

E 

D 

= Actuated Length 

D 

= Actuated Length 



C 

B 

B 

11

12 

MPC Series Couplings 

Material: Medical-Grade Polycarbonate and Polysufone 

MPC Series couplings add ease of use and security to your most 

critical fluid handling applications. Choose from a full line of 

connectors and configurations, including pressure sealing caps and 

plugs in sizes to fit 1/4” and 3/8” tubing. MPC couplings offer 

optional locking sleeves to further guard against accidental 

disconnects. 


Ergonomic thumb latch Easy to operate–even with gloved hands 

Audible “click” when connected Assures connection is secure 

Meets USP Class VI criteria, and 

MEM elution, agarose overlay and 

hemolysis in vitro (see page 22) 

Acceptable for a wide variety of applications 

Sterilizable by autoclave, Et0, Reusable, yet economical enough to allow 

e-beam, or gamma (see page 22) disposability 

Coupling halves can be rotated 

when connected 

Reduces tube kinks 

Thin, tapered barb minimizes dead Minimizes fluid turbulence and decreases 

space between tubing and coupling area for particle entrapment 

All measurements are in inches (millimeters) unless otherwise noted. Tubing must meet stated inside diameters. 

Coupling Bodies 

Polycarbonate 

In-Line 

Hose Barb 

In-Line 

Hose Barb with Lock 

Polysulfone 

In-Line 

Hose Barb 

In-Line 


Tethered Caps & Plugs 

PVC 

Applications may include: 

• Cell culture media 

packaging and transfer lines 

• Harvest and collection 

applications 

• Buffer solutions 

• Tube sets 

• Urology drainage/collection 

systems 

• Hypo/hyperthermia blankets 

TUBING METRIC EQ. FLOW PART NO. HEIGHT LENGTH TERM. LENGTH 

1/4" ID 6.4mm .210" MPC17004T03 .93 (23.6) 1.30 (33.0) .60 (15.2) 

3/8" ID 9.5mm .290" MPC17006T03 .93 (23.6) 1.30 (33.0) .60 (15.2) 


1/4" ID 6.4mm .210" MPCK17004T03 .99 (25.2) 1.30 (33.0) .60 (15.2) 

3/8" ID 9.5mm .290" MPCK17006T03 .99 (25.2) 1.30 (33.0) .60 (15.2) 


1/4" ID 6.4mm .210" MPC17004T39 .93 (23.6) 1.30 (33.0) .60 (15.2) 

3/8" ID 9.5mm .290" MPC17006T39 .93 (23.6) 1.30 (33.0) .60 (15.2) 


1/4" ID 6.4mm .210" MPCK17004T39 .99 (25.2) 1.30 (33.0) .60 (15.2) 

3/8" ID 9.5mm .290" MPCK17006T39 .99 (25.2) 1.30 (33.0) .60 (15.2) 

MATERIALS TUBING SIZE PART NO. DESCRIPTION 

Soft, flexible, For use with MPC coupling MPC30L Leash plug for MPC body 

medical-grade PVC inserts and bodies MPC32L Leash cap for MPC insert 



MPC Series Specifications 

Polycarbonate and Polysulfone 

Pressure: Vacuum to 60 psi, 4.14 bar 

Temperature: -40° F to 300° F, Polysulfone 

-40° C to 148.9° C 

-40° F to 250° F, Polycarbonate 

-40° C to 121° C 

Materials: 

Main components: Polysulfone (amber), USP Class VI 

Polycarbonate (purple tint), USP Class VI 

Locking sleeves: Polysulfone (white) 


Tubing Sizes: 1/4" and 3/8" ID 

6.4mm and 9.5mm ID 


Coupling Inserts 

Polycarbonate 

Silicone Seal 

USP Class VI 

Polysulfone 

Silicone Seal 

USP Class VI 

Sealing Caps 

Polycarbonate 

Polysulfone 

Sealing Plugs 

Polycarbonate 

Silicone Seal 

USP Class VI 

Polysulfone 

Silicone Seal 

USP Class VI 


1/4" ID 6.4mm .210" MPC22004T03M .60 (15.2) 1.30 (33.0) .61 (15.5) 

3/8" ID 9.5mm .290" MPC22006T03M .60 (15.2) 1.30 (33.0) .61 (15.5) 


1/4" ID 6.4mm .210" MPC22004T39M .60 (15.2) 1.30 (33.0) .61 (15.5) 

3/8" ID 9.5mm .290" MPC22006T39M .60 (15.2) 1.30 (33.0) .61 (15.5) 

SEALING CAP SEALING CAP W/LOCK HEIGHT LENGTH 

MPC32003 MPCK32003 .93 (23.6) 1.30 (33.0) 


MPC32039 MPCK32039 .99 (25.2) 1.30 (33.0) 

SEALING PLUG HEIGHT LENGTH 

MPC30003M .75 (19.1) 1.24 (31.5) 


MPC30039M .75 (19.1) 1.24 (31.5) 



13

14 

MPX Series Couplings 

Material: Polycarbonate and Polysulfone 

MPX Series couplings add ease of use and security to your most 

critical fluid handling applications. Choose from a full line of 

connectors and configurations, including pressure sealing caps and 

plugs in sizes to fit 3/8” and 1/2” tubing. MPX couplings offer 

optional locking sleeves to further guard against accidental 

disconnects. 


Ergonomic thumb latch Easy to operate–even with gloved hands 


Meets USP Class VI criteria, and 

MEM elution, agarose overlay and 

hemolysis in vitro (see page 22) 

Acceptable for a wide variety of applications 

Sterilizable by autoclave, Et0, Reusable, yet economical enough to allow 

e-beam, or gamma (see page 22) disposability 

Coupling halves can be rotated 

when connected 

Reduces tube kinks 

Thin, tapered barb minimizes dead Minimizes fluid turbulence and decreases 

space between tubing and coupling area for particle entrapment 



Polycarbonate 

In-Line 

Hose Barb 

In-Line 


Polysulfone 

In-Line 

Hose Barb 

In-Line 



• Cell culture media 

packaging and transfer lines 


applications 

• Buffer solutions 

• Tube sets 

• Flexible bag systems 


1/2" ID 12.7mm .500" MPX17803 1.28 (32.5) 1.96 (49.8) .89 (22.6) 


1/2" ID 12.7mm .500" MPXK17803 1.28 (32.5) 1.96 (49.8) .89 (22.6) 


1/2" ID 12.7mm .500" MPX17839 1.28 (32.5) 1.96 (49.8) .89 (22.6) 


1/2" ID 12.7mm .500" MPXK17839 1.28 (32.5) 1.96 (49.8) .89 (22.6) 



MPX Series Specifications 


Temperature: -40° F to 300° F, Polysulfone 

-40° C to 148.9° C 

-40° F to 250° F, Polycarbonate 

-40° C to 121° C 

Materials: 

Main components: Polysulfone (amber), USP Class VI; 

Polycarbonate (purple tint), USP Class VI 

Locking sleeves: Polysulfone (white) 


Tubing Sizes: 3/8" to 1/2" ID 

9.5mm to 12.7mm ID 



Polycarbonate 

Silicone Seal 

USP Class VI 

Polysulfone 

Silicone Seal 

USP Class VI 

Sealing Caps 

Polycarbonate 

Polysulfone 

Sealing Plugs 

Polycarbonate 

Silicone Seal 

USP Class VI 

Polysulfone 

Silicone Seal 

USP Class VI 


3/8" ID 9.5mm .375" MPX22603M .85 (21.6) 1.90 (48.3) .94 (23.9) 

1/2" ID 12.7mm .500" MPX22803M .85 (21.6) 1.90 (48.3) .94 (23.9) 


3/8" ID 9.5mm .375" MPX22639M .85 (21.6) 1.90 (48.3) .89 (22.6) 

1/2" ID 12.7mm .500" MPX22839M .85 (21.6) 1.90 (48.3) .89 (22.6) 


MPX32003 MPXK32003 1.28 (32.5) 1.67 (42.4) 


MPX32039 MPXK32039 1.28 (32.5) 1.67 (42.4) 


MPX30003M 1.10 (27.9) 1.66 (42.2) 


MPX30039M 1.10 (27.9) 1.66 (42.2) 



15

16 


Material: 316 Stainless 

Colder’s new SaniQuik connection answers the question of how 

to integrate disposables with your existing stainless processing 

equipment. This integral sanitary termination attaches to hardplumbed 

systems with tri-clover clamps. Once attached it permits 

quick and easy connection to single-use bag systems, manifolds 

or tube sets which incorporate Colder disposable couplings. 

SaniQuik connections reduce sanitary gasket replacement, 

enabling cost-effective media transfer solutions for feeding, 

harvesting or sampling applications. 


316 stainless Withstands multiple sterilization cycles 

1-1/2” and 3/4” sanitary Connects to hard plumbed systems with 

standard terminations sanitary gasket and tri-clover clamps 

Compatible with MPC and Quick and easy connections to industry 

MPX Series standard plastic couplings used on 

disposable bag and tube sets 

Integral coupling adaptor Disconnecting coupling reduces sanitary 

gasket replacement 

USP Class VI platinum-cured Meets industry material compatibility 

silicone seal requirements 

SaniQuik Specifications 


Temperature: -40° F to 300° F (-40° C to 148.9° C) 

Sterilization: Autoclave 


• Flexible bags 

• Media transfer lines 

• Bioreactor feeding 

• Cell harvesting 

• Stainless and glass 

vessel filling 

• Chromatography 

• Filtration 

Materials: 

Main component: 316 stainless 




PART NUMBER MATING COUPLING BODY SANITARY SIZE SANITARY BORE HEIGHT LENGTH 

SQCC221212M MPC Series 3/4" 3/4" .89" (22.6) 1.39" (35.3) 

SQCC222424M MPC Series 1-1/2" 1-1/2" 1.98" (50.3) 1.50" (38.1) 

SQCX221212M MPX Series 3/4" 3/4" .89" (22.6) 1.54" (39.1) 

SQCX222416M MPX Series 1-1/2" 1" 1.98" (50.3) 1.50" (38.1) 

SQCX222424M MPX Series 1-1/2" 1-1/2" 1.98" (50.3) 1.50" (38.1) 

Mates with: MPC Polycarbonate and Polysulfone bodies and sealing caps (see pages 12 and 13) 

and MPX Polycarbonate and Polysulfone bodies and sealing caps (see pages 14 and 15). 

Replacement Seals 

Silicone (clear), Platinum-cured USP Class VI 

PART NO. MATING SANIQUIK 

143700 SQCC221212M, SQCC222424M 

934000 SQCX221212M, SQCX222416M, SQCX222424M 



Sanitary Series 

Material: Polysulfone 

Sanitary couplings attach directly to popular 3/4" mini and 

1" maxi size sanitary connections, eliminating the need for 

cumbersome adapters or tubing assemblies. Direct attachment 

allows faster connection to and disconnection from installed, 

rigid and flexible piping systems. 


Attaches directly to sanitary Eliminates the need for cumbersome adapters 

hardware assemblies or tubing; provides thumb latch convenience 

3/4" mini & 1" maxi sanitary Popular sanitary sizes can now be used with 

termination sizes the convenience of the Colder quick disconnect 

Colder sanitary couplings attach Installed with your existing hardware and 

to your sanitary connections with provides a reliable, secure seal 

standard gaskets and clamps 

USP Class VI polysulfone material Provides durability, compatible with your 

existing processes and can be sterilized for 

reusability (see page 22) 

Sanitary Series Specifications 


Temperature: -40° F to 300° F, -40° C to 148.9° C 

Termination Size: 3/4” mini and 1” maxi 

19.0mm and 25.4mm 


• Piping systems 

• Bioreactors 

• Fermentation systems 

• Bioprocessing labs 

• Cell culture media transfer 

• Filtration equipment 

Materials: 

Main components: Polysulfone (amber tint) 

Seals (mating insert)*: Silicone (clear), platinum-cured, 

USP Class VI 



Polysulfone 


Polysulfone 

Silicone Seal 

USP Class VI 

*Mating inserts detailed on this page are polysulfone. 

MPC and MPX mating inserts are available in 

polycarbonate. Please refer to pages 12 – 15 of this 

catalog for further information. 

**QD sanitary couplings are compatible with both 

stainless steel and plastic clamps. Clamps and 

gaskets are referenced for illustration and are not 

available through Colder. 

SANITARY SIZE SANITARY O.D. PART NO. HEIGHT LENGTH 

3/4" Mini 1.0" 25.4mm MPC3301239 .98 (24.9) 1.40 (35.6) 

1" Maxi 1.5" 38.1mm MPC3301639 1.50 (38.1) 1.40 (35.6) 

3/4" Mini 1.0" 25.4mm MPX3301239 1.28 (32.5) 1.70 (43.2) 


1/4" ID 6.4mm .210" MPC22004T39M .60 (15.2) 1.30 (33.0) .61 (15.5) 

3/8" ID 9.5mm .290" MPC22006T39M .60 (15.2) 1.30 (33.0) .61 (15.5) 

3/8" ID 9.5mm .375" MPX22639M .85 (21.6) 1.90 (48.3) .89 (22.6) 

1/2" ID 12.7mm .500" MPX22839M .85 (21.6) 1.90 (48.3) .89 (22.6) 

Quick Disconnect Sanitary 

Coupling attaches to sanitary 

connector or hardware** 

3/4" mini and 

1" maxi sizes 

Clear polysulfone 

provides flow visibility Leak-free 

silicone o-ring 

Thumb latch design 

provides quick disconnect 

with Colder insert 

Inserts available for 

use with 1/4", 3/8" 

and 1/2" size tubing 



17

18 

MPU Series Couplings 


The MPU’s twist-to-connect design features an easy-to-use 

locking mechanism that guards against accidental disconnects 

and provides a reliable, secure connection. A 3/4" hose barb 

provides smooth, rapid media transfer. 


3/4" hose barb Facilitates rapid fill and empty of 

bioprocessing bags 


Locking feature Guards against accidental disconnect 

Medical-grade polysulfone Compatible with popular sterilization methods, 

yet economical enough to allow disposibility 

Sharp barb end Minimizes fluid turbulence and dead space 

Shrouded, leak-free seal and Protects valuable fluids and eliminates 

smooth, internal flow path potential to contaminate fluid path 

Low profile Offers ease of use and handling 

Lightweight Removes extra weight from assemblies 

MPU Series Specifications 



Tubing Sizes: 3/4” ID, 19mm ID 


Coupling Body 

Polysulfone 

In-Line 

Hose Barb 

Coupling Insert 

Polysulfone 

Silicone Seal 

USP Class VI 

Sealing Cap 

Polysulfone 

Sealing Plug 

Polysulfone 


• Laboratory tubing 

connections 

• Cell culture media packaging 

and transfer lines 


applications 

• Diagnostic manufacturing 

• Compression therapy cuffs 

Materials: 

Main components: Polysulfone (amber tint), USP Class VI 



3/4'' ID 19mm .710" MPU171239 1.75 (44.5) 2.37 (60.2) 1.50 (38.1) 


3/4'' ID 19mm .710" MPU221239M 1.56 (39.6) 2.88 (73.2) 1.50 (38.1) 

DESCRIPTION PART NO. HEIGHT LENGTH 

Cap for: MPU221239M MPU32039 1.75 (44.5) .79 (20.1) 

DESCRIPTION PART NO. HEIGHT LENGTH 

Plug for: MPU171239 MPU30039M 1.56 (39.6) 1.38 (35.1) 

Sharp hose barb minimizes 

fluid turbulence 

All USP Class VI 

flow path Shrouded seal reduces 

potential for contamination 

Latch guards against 

accidental disconnect 

USP Class VI silicone 

o-rings 

Smooth 

internal flow 

path reduces 

catch points 



HFC39 Series High Flow 

Couplings 


HFC39 couplings feature automatic shutoff valves, and offer a 

cost-effective replacement for expensive, heavy, stainless steel 

connectors or fittings. HFC’s medical-grade polysulfone meets the 

most stringent requirements such as USP Class VI, MEM elution, 

agarose overlay, hemolysis in vitro, and USP physicochemical tests. 


Automatic shutoff valves Stops flow and eliminates need for awkward 

pinch clamps 

Audible “click” when engaged Confidence of a secure connection 

USP Class VI polysulfone material Physical strength, durability and an excellent 

replacement for stainless steel 

Sterilizable by autoclave, Et0, Reusable and compatible with your existing 

E-beam, or gamma (see page 22) processes 

Lightweight Removes extra weight from assemblies 

HFC39 Series Specifications 



Tubing Sizes: 1/4", 3/8" and 1/2" ID 

6.4mm, 9.5mm and 12.7mm ID 

Patent Protected 



• Bioprocessing 

• Laboratory tubing 

connections 

• Cell culture media transfer 

• Kidney dialysis equipment 

• Pharmaceutical equipment 

• Diagnostic manufacturing 

Materials: 

Main components: Polysulfone (amber tint), USP Class VI 


Springs: 316 stainless steel 



Polysulfone 

In-Line 

Hose Barb 


Polysulfone 

Silicone Seal 

USP Class VI 

TUBING METRIC EQ. FLOW STRAIGHT THRU SHUTOFF HEIGHT LENGTH TERM. LENGTH 

1/4" ID 6.4mm ID 1/4" HFCD17439M 1.44 (36.6) 2.82 (71.6) .65 (16.5) 

3/8" ID 9.5mm ID 3/8" HFCD17639M 1.44 (36.6) 2.82 (71.6) .65 (16.5) 

1/2" ID 12.5mm ID 3/8" HFCD17839M 1.44 (36.6) 2.82 (71.6) .65 (16.5) 

TUBING METRIC EQ. FLOW STRAIGHT THRU SHUTOFF HEIGHT LENGTH TERM. LENGTH 

1/4" ID 6.4mm ID 1/4" HFC22439M HFCD22439M 1.00 (25.4) 2.02 (51.3) .65 (16.5) 



Clear polysulfone 

provides flow visibility 

Excellent laminar flow 

in both directions 

Shutoff valves for 

automatic flow stop 

Push-button thumb latch 

for easy disconnects 

High-efficiency valves for 

low pressure drop 


USP Class VI 

silicone o-rings 

19

20 

ChemQuik ® CQG06 Series 

Material: Polypropylene 

The CQG06 Series is the lowest cost version of our pressurebalanced, 

non-spill, high purity couplings. Molded, virgin 

polypropylene, Viton ® seals, and a 100% springless and 

metal-free flow path provide broad chemical resistance. CQG06 

couplings offer exceptionally high flow capacity, allowing 

instant disconnects (and reconnects), even under pressure. 


Non-spill design Ultimate protection from chemicals and 

fumes 

Pressure-balanced design Failsafe disconnect, even under pressure 

Springless flow path design Eliminates source of metallic contaminants 

Mechanical keying system Helps prevent accidental misconnects 

CQG06 Series Specifications 

Pressure: See graph 

Temperature: See graph 

Materials: 

Main components: Natural, virgin polypropylene 

Seals: Viton ® FKM, Simriz ® ChemQuik 

FFKM perfluoroelastomer (optional) 

Springs (non-wetted): Hastelloy C 

Flare nuts: PVDF 

® CQHD06 Flow Performance 

60 7.6 (lpm) 15.1 22.7 30.3 37.9 45.4 

4.14 

50 

3.44 

40 

2.75 

30 

2.07 

20 

Cv~1.6 

1.38 

10 

0.69 

Pressure Drop (psid) 

Lubricants: None used 

0 

0.0 

2.0 4.0 6.0 8.0 10.0 12.0 

Flow Rate (gpm) 

Spillage (air inclusion):

DrumQuik ® MODULAR 

Dispense System 

Material: Polypropylene and PTFE 

The easy-to-use DrumQuik ® chemical dispense system combines 

your choice of ChemQuik ® couplings with a modular dip-tubebased 

system for the extraction of aggressive or ultra-pure 

chemcials from drums and IBCs. This reliable, closed system 

increases operator safety and reduces downtime by eliminating 

dangerous spills and fumes. 


Modular design Provides flexibility in system configuration 

Two-port system Eliminates fumes and allows N2 ports and recirculation 

Standard threads Fits common drum bungs 

DrumQuik Specifications (will vary based on couplings and container selected) 

Pressure: 0 to 45 psig, 0 to 3.10 bar 

Temperature: 0° F to 150° F, -17° C to 65° C; 

polypropylene limited to 32° F, 0° C 

Materials: 

Main components: Natural, virgin PTFE or polypropylene 

Dip-tube seal: FEP Encapsulated Viton ® FKM 

Vent check valve: PVDF with Hastelloy C spring, Viton ® seal 

Back flow check valve: See note below; PFA, Kalrez ® seal 

Seal kits: EPDM, Viton ® FKM, FEP Encapsulated Viton ® 

Lubricants: None used 

Coupling components: Dependent on coupling 

(see catalog for specifications) 

Standard Products 

Drum Inserts 

Dip-Tubes 

Seal Kits 

Pipe Plugs 

Vent Check Valve (VCV) 

(prevents fumes from escaping) 

Back Flow Check Valve (BCV) 

(prevents return flow to drum) 

Construction Type: Modular drum insert bung and dip-tube 

Number of Ports: Two; one 3/4” female NPT liquid port and 

one 3/8” female NPT vent port (with backup seals) 

Drum Thread: Industry standard 2” buttress and 2” NPS 

(others available) 

Dip-Tube Length: 35.3” (897mm) or 55” (1397mm) 

(measured from sealing surface) 

NOTE: Some applications require the use of a back flow check valve (BCV) 

which prevents reverse flow when suction pump is turned off. Colder 

recommends that the BCV be installed immediately downstream from the 

liquid line coupling body. Similarly, to allow air into drum, but prevent fumes 

from escaping, install a vent check valve (VCV) in vent port. Contact Colder 

factory for assistance. 

DESCRIPTION PART NO. 

Bung, polypropylene, 3/4” NPT liquid port, 3/8” NPT vent, 2” buttress DQMDI2PP2BUT 

Bung, polypropylene, 3/4" NPT liquid port, 3/8” NPT vent, 2" NPS DQMDI2PTFE2NPS 

Bung, PTFE, 3/4” NPT liquid port, 3/8” NPT vent, 2” buttress DQMDI2PTFE2BUT 

Bung, PTFE, 3/4" NPT liquid port, 3/8" NPT vent, 2" NPS DQMDI2PP2NPS 


Dip-tube, polypropylene, 35.3” (897mm) long from sealing surface DQMDTUBEPP35 

Dip-tube, polypropylene, 55” (1397mm) long from sealing surface DQMDTUBEPP55 

Dip-tube, PTFE, 35.3” (897mm) long from sealing surface DQMDTUBEPTFE35 

Dip-tube, PTFE, 55” (1397mm) long from sealing surface DQMDTUBEPTFE55 


Complete seal kit (liquid and vent ports and bung), EPDM DQMSKITEPDM 

Complete seal kit (liquid and vent ports and bung), Viton ® DQMSKITVITON 

Complete seal kit (liquid and vent ports and bung), FEP encap, Viton ® DQMSKITFEPVITON 


Hex pipe plug, 3/8” NPT, PFA material DQMPLUGPFA06 

Hex pipe plug, 3/8” NPT, PFA material DQMPLUGPFA12 


For DrumQuik vent port DQMCKPVDF0206 


Mount downstream of liquid coupling DQMCVPFA0308 


• Clean-in-place 

• Process chemical delivery 

from drums and IBC 

(tote) connections for CIP 

and process chemicals 



21

22 

Technical Information 

Sterilization Methods 

PRODUCT SERIES MATERIAL AUTOCLAVE ETO GAMMA IRRADIATION E-BEAM 

MPC/MPX Polycarbonate YES* YES YES* YES* 

at 250° F for up to five cycles up to 50 Kilograys; up to 50 Kilograys; 

30 minutes, up coupling color shift to coupling color shift to 

to 10 cycles clear at 25 Kilograys clear at 25 Kilograys 

**Steam-Thru Polysulfone YES NO YES NO 

at 128° C (265° F) up to 50 Kilograys, 

for 30 minutes, up to for one cycle 

two cycles (applies only to part 

numbers STC1700500-1700800) 

MPC/MPX 

MPU 

Quick Disconnect 

Sanitary 

HFC39 

**Steam-Thru ® Connections are compatible with SIP sterilization up to 30 psi and 266° F in combination with the gamma or autoclave 

sterilization methods as outlined above. Colder does not suggest the combination of all three sterilization methods on a single STC assembly. 

Polysulfone YES* YES YES* YES* 

at 270° F for up to five cycles up to 50 Kilograys up to 50 Kilograys 

60 minutes, 

up to 25 cycles 

MPC Tethered Vinyl NO YES YES YES 

Caps and Plugs up to 5 cycles up to 50 Kilograys up to 50 Kilograys 

*Colder Products Company did not conduct any sterilization test above 50 Kilograys. Bodies and inserts 

should remain uncoupled during autoclave sterilization. Manufacturer’s specifications for materials 

stated above may differ from Colder’s actual test results. Et0 cycle parameters available upon request. 

Working pressures and other technical information have been prepared from actual test results and 

other data considered to be reliable. Sterilization process outcomes vary substantially depending on 

equipment and specific process. Colder represents the sterilization methods information as reference 

only. Since so many factors affect the sterilization capability of a material, it is the customer’s 

responsibility to test Colder products under their own sterilization conditions. 

Biocompatibility Testing 

MPC/MPX, Steam-Thru, MPU, QD Sanitary, and HFC39 satisfy stringent 

requirements such as USP Class VI criteria, as well as MEM elution, agarose 

overlay, hemolysis in vitro, and USP physicochemical tests. Test results 

available upon request. 



Still Looking for the Perfect Solution? 

Even with thousands of standard quick disconnect couplings available, we know you still may not have 

found the precise part you need. That’s why, for more than 28 years, Colder’s Application Engineering Team 

has worked with customers around the world to design custom coupling solutions to solve their specific 

problems and improve their products’ performance. Colder has solid modeling capabilities, prototype 

equipment, an expansive test lab, and thousands of solutions. Combine that with our years of experience 

and a “can do” attitude, and there is no need for you to design your solution alone. 

Consider a Custom-Designed Connector When: 

■ A quick disconnect will add value to your product, making it easier to use and more reliable 

■ Your requirements cannot be met by a standard Colder product 

■ Unique requirements, budgets or timing warrant your designer’s collaboration with Colder’s 

Application Engineering Team 

Remember, standard catalog items generally have the advantage of quick availability 

and many times, lower cost, with no initial investment of time or money. 

However, depending on your volumes and technical requirements, it may make 

sense to work with our Application Engineering Team to design a unique 

solution tailored for your needs. 

Custom-designed products are exclusively produced for a specific customer. These proprietary products might not be for sale. 

Contact your local distributor for special application couplings. 



23

Colder Patent Statement: 

Colder Products Company takes pride in 

its innovative quick disconnect coupling 

solutions, many of which have been 

awarded United States and international 

patents. Colder Products Company has a 

strong tradition of leadership in the quick 

disconnect market, and aggressively 

pursues and protects its proprietary 

information and intellectual property. In 

cases where it is practical and as a benefit 

to its customers, Colder Products Company 

has licensed its proprietary technology. 

Please contact Colder Products to discuss 

your unique needs. 

SaniQuik is a trademark with the US Patent 

and Trademark Office. 

ChemQuik ® , DrumQuik ® and Steam-Thru ® are 

registered trademarks and with the US Patent 

and Trademark Office. 

Chemraz ® is a registered trademark of 

Greene, Tweed & Co. Simriz ® is a registered 

trademark of Freudenberg-NOK. Teflon ® 

is a registered trademark of DuPont Dow 

Elastomers. Viton ® is a registered trademark 

of DuPont Dow Elastomers. Dyneon is a 

trademark of 3M-Hoechst. 

Colder Products Company 

1001 Westgate Drive 

St. Paul, Minnesota 55114 

U.S.A. 

Phone: 651-645-0091 

Fax: 651-645-5404 

Toll Free: 800-444-2474 

info@colder.com 

www.colder.com 

Distributed By: 

Colder Products Company GmbH 

Schmalweg 50 

D-55252 Mainz-Kastel 

Germany 

Phone: +49-6134-2878-0 

Fax: +49-6134-287828 

cpcgmbh@colder.com 


Colder Products Company Limited 

Room 1503, 15/F, SBI Center 

54 – 58 Des Voeux Road Central 

Hong Kong 

Phone: 852-2987-5272 

Fax: 852-2987-2509 

asiapacific@colder.com 


Colder Warranty Statement: Colder Products Company warrants its products against defects in workmanship and materials for a period of 

12 months from the date of sale by Colder Products Company to its initial customer (regardless of any subsequent sale of the products). 

This warranty is void if the product is misused, altered, tampered with or is installed or used in a manner that is inconsistent with Colder 

Product Company’s written recommendations, specifications and/or instructions, or fails to perform due to normal wear and tear. Colder 

Products Company does not warrant the suitability of the product for any particular application. Determining product application suitability 

is solely the customer's responsibility. Colder Products Company is not liable for special, indirect, incidental, consequential or other damages 

including, but not limited to, loss, damage, personal injury, or any other expense directly or indirectly arising from the use of or inability to 

use its products either separately or in combination with other products. ALL OTHER WARRANTIES EXPRESS OR IMPLIED, WHETHER ORAL, 

WRITTEN OR IN ANY OTHER FORM, INCLUDING BUT NOT LIMITED TO WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A 

PARTICULAR PURPOSE, ARE EXPRESSLY EXCLUDED. 

The sole and exclusive remedy under this warranty is limited, at the option of Colder Products Company, to replacement of the defective 

product or an account credit in the amount of the original selling price. All allegedly defective Colder Products Company products must be 

returned prepaid transportation to Colder Products Company, together with information describing the product's application and 

performance, unless otherwise authorized in writing by Colder Products Company. 

Copyright © 2004-2006 by Colder Products Company. All rights reserved. Colder Products Company, 

Colder Products and CPC are registered trademarks with the US Patent & Trademark Office. LICP54 11/06 DG/2M Printed in the U.S.A

Quick Disconnect Couplings for - Colder Products Company

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