Chapter 7 - Oakland University

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The structure of the 16S rRNA at the P and A sites of the ribosome influences the accuracy of translation. Charging a tRNA only with its correct amino acid clearly is critical. This is a function of the aminoacyl-tRNA synthetase. Probably the error rate varies with the particular enzyme, but generally mistakes occur in
Recoding events occur when the meaning of a codon or series of codons is changed from that predicted by the genetic code. It may involve altered interactions between aminoacyl-tRNA and mRNA that are influenced by the ribosome Changes in codon meaning can be caused by mutant tRNAs or by tRNAs with special properties. The reading frame can be changed by frameshifting or bypassing, both of which depend on properties of the mRNA.
Page 1 and 2: Genetic Code Chapter 7 By Rasul Cha
Page 3 and 4: # of codons/amino acid
Page 5 and 6: Codon-anticodon recognition involve
Page 7 and 8: Unusual pairing possible at 3 rd ba
Page 9 and 10: A mature tRNA is generated by proce
Page 11 and 12: • The many tRNA-modifying enzymes
Page 13 and 14: Restricted Pairing
Page 15 and 16: • In Mycoplasma capricolum, UGA c
Page 17 and 18: The insertion of seleno-Cys Cys-tRN
Page 19 and 20: • Mutations in 4 sel genes create
Page 22 and 23: Crystal structures of aminoacetyl t
Page 24 and 25: Specificity of recognition of both
Page 28 and 29: A suppressor is a second mutation t
Page 30 and 31: The general importance of these obs
Page 34 and 35: Frameshifting typically involves ch
Page 36 and 37: In retroviruses, translation of the

Chapter 7 - Oakland University

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