Chapter 2 Biological Inventions - Japan Patent Office

Part VII Chapter 2 Biological Inventions
(a) a protein whose amino acid sequence is represented by Met-Tyr-Cys-Leu
(b) a protein derived from the protein of (a) by substitution, deletion or addition of one or
several amino acids in the amino acid sequence defined in (a) and having the activity of
enzyme A.
[Note]
The protein (a) has the activity of enzyme A.
The gene encoding the protein (b) is described in the detailed description of the
invention in such a manner that a person skilled in the art can make the said gene without
large amount of trials and errors or complicated experimentation beyond the reasonable
extent that can be expected from a person skilled in the art who is supposed to have
ordinary skill.
Example 2:
A gene selected from the group consisting of:
(a) a DNA whose nucleotide sequence is represented by ATGTATCGG・・・TGCCT
(b) a DNA which hybridizes under stringent conditions to the DNA, whose nucleotide
sequence is complementary to that of the DNA defined in (a) and encodes the human
protein having the activity of enzyme B.
[Note]
A protein encoded by the DNA (a) has the activity of enzyme B.
"Stringent conditions" are described in the detailed description of the invention.
4 A gene may be described by specifying functions, physiochemical properties, origin or
source of the said gene, a process for producing the said gene, etc. (provided that the claimed
invention is clear and the enablement requirement is met (See 1.1.2.1 below)).
(2) Vectors
A vector should be described by specifying a base sequence of its DNA, a cleavage map of
DNA, molecular weight, number of base pairs, source of the vector, process for producing the
vector, function or characteristics of the vector, etc.
[Note] A cleavage map is a map which shows the relative location and distance of the cleavage
sites by various restriction enzymes.
(3) Recombinant vectors
A recombinant vector may be described by specifying at least one of the gene and the vector.
Example:
A recombinant vector containing a DNA whose base sequence is represented by ACAGCA・・・・・・
AGTCAC.
(4) Transformants
A transformant may be described by specifying at least one of 1 its host and 2 the gene which
is introduced (or the recombinant vector) (provided the that the claimed invention is clear and
enablement requirement is met (See 1.1.2.1 below)).
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