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Venous Thromboembolism Prophylaxis Who, when and what?

Venous Thromboembolism Prophylaxis Who, when and what?

Venous Thromboembolism Prophylaxis Who, when and what?

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Adequate Thromboprophylaxis in<br />

Critically Ill Patients<br />

• Critically ill patients may need much higher<br />

doses of LMWH than other patients<br />

• Reasons<br />

- full immobilisation<br />

- limited bioavailability (oedema, vasopressors)<br />

- impaired protein binding<br />

Robinson S, et al. Critical Care 2010; 14: R41<br />

Levi M. Critical Care 2010; 14: 142<br />

Priglinger U, et al. Crit Care Med 2003; 31: 1405-1409<br />

Haas CE, et al. J trauma 2005; 59; 1336-1343

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