Venous Thromboembolism Prophylaxis Who, when and what?
Venous Thromboembolism Prophylaxis Who, when and what?
Venous Thromboembolism Prophylaxis Who, when and what?
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Prothrombin time (s)<br />
Correlation of prothrombin time with rivaroxaban<br />
plasma concentration<br />
40<br />
Healthy human subjects<br />
30<br />
20<br />
r = 0.958<br />
10<br />
0<br />
Caveat: INR values must not be compared with<br />
those obtained with warfarin !!!<br />
0 100 200 300 400 500 600<br />
Plasma concentration of rivaroxaban (µg/L)<br />
Kubitza D, et al., Eur J Clin Pharmacol 2005;61:873–80.
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