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Table of Contents<br />

word of welcome by the congress chairs 3<br />

word of welcome by the president 4<br />

acknowledgements 5<br />

Committees 6<br />

Awards 8<br />

congress related meetings 9<br />

Poster Viewing 9<br />

corporate Workshops 10<br />

Monday 18 <strong>August</strong> 10<br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong> 12<br />

Wednesday 20 <strong>August</strong> 14<br />

Floor plans Congress Venue <strong>19</strong><br />

List of Exhibitors 21<br />

ORAL PRESENTATIONS<br />

Program Saturday 16 <strong>August</strong> 23<br />

Program at a glance 23<br />

HUPO Educational Day 24<br />

HUPO Initiatives Program 24<br />

Program Sunday 17 <strong>August</strong> 31<br />

Program at a glance 31<br />

HUPO Clinical Day 32<br />

HUPO Initiatives Program 33<br />

Program Monday 18 <strong>August</strong> 35<br />

Program at a glance 35<br />

Plenary speakers 38<br />

Full program details 42<br />

1


Table of Contents<br />

Program <strong>Tuesday</strong> <strong>19</strong> <strong>August</strong> 47<br />

Program at a glance 47<br />

Plenary speakers 48<br />

Full program details 52<br />

Program Wednesday 20 <strong>August</strong> 59<br />

Program at a glance 59<br />

Plenary speakers 60<br />

Full program details 62<br />

poster topics 66<br />

Poster listing 68<br />

Monday 18 <strong>August</strong> 68<br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong> 98<br />

Wednesday 20 <strong>August</strong> 128<br />

Information for Oral and Poster Presenters 159<br />

Exhibition Information 160<br />

General Information 161<br />

Social Program 165<br />

Accompanying Persons Tour / excursion 166<br />

Exhibitor and sponsor listing 167<br />

Hotel Map 176<br />

Word of welcome by the<br />

congress chairs<br />

Dear Colleagues<br />

On behalf of the HUPO 2008 Amsterdam Congress Organizing Committee, HUPO and<br />

EuPA, we would like to extend our warm welcome to all of you attending the HUPO<br />

7th Annual World Congress held in the RAI Convention Centre in Amsterdam, The<br />

Netherlands. We like to thank you for your participation as presenter, exhibitor and/<br />

or attendee.<br />

The theme of the meeting is “Proteome Biology”. With this title the Organizing<br />

Committee wants to indicate that in spite of the amazing complexity of the proteome,<br />

the field of proteomics has matured to a degree where significant progress in biology<br />

and medicine can be realized by applying the powerful proteomic technologies. This<br />

expectation is based on rapid progress in the development of a range of technologies<br />

that increasingly contribute to the editing of comprehensive maps of the various cells’<br />

proteomes and move forward the boundaries of the “terra incognita”. The title of the<br />

meeting should also indicate the need for proteomics to progress beyond identifying the<br />

building blocks of the proteome towards understanding of how the complex biological<br />

functions of a cell are orchestrated via intricate networks of proteins interacting with<br />

themselves and other types of biomolecules.<br />

The meeting offers a full program with more than 140 lectures, 1200 posters,<br />

the Clinical Day and Educational sessions, the HUPO Initiatives progress meetings,<br />

corporate workshops, and a full exhibition with the latest technologies.<br />

Besides a challenging scientific program we also organised a very attractive social<br />

program! We hope that together with all of you we can create a scientifically creative and<br />

socially lively atmosphere at the meeting, whereby the presentations and discussions<br />

will contribute to further progress in the field of proteomics.<br />

Sincerely yours,<br />

Chairs of the HUPO 2008 meeting<br />

Albert Heck<br />

Utrecht University<br />

Netherlands Proteomics Centre<br />

Anne-Claude Gavin<br />

EMBL Heidelberg<br />

Ruedi Aebersold<br />

ETH Zurich and University of Zurich<br />

Institute for Systems Biology, Seattle<br />

2 3


Word of welcome by the<br />

President<br />

Dear Colleagues,<br />

On behalf of the Human Proteome Organisation I welcome you to the HUPO 7th Annual<br />

World Congress in Amsterdam.<br />

This year’s congress is entitled “Proteome Biology” and it emphasizes the need for<br />

proteomics to progress beyond identifying the building blocks of the proteome towards<br />

understanding of how the complex biological functions of a cell are orchestrated<br />

via intricate networks of proteins interacting with themselves and other types of<br />

biomolecules.<br />

Building on the success of HUPO’s past congresses, this collaborative effort between<br />

HUPO and EuPA to bring you once again “The can’t miss <strong>event</strong> of the year” in proteomics,<br />

has built a powerful scientific program led by visionaries in proteomics, and pioneers<br />

in education.<br />

Since proteomics depends heavily on the technologies that will drive this discipline<br />

forward, I am especially pleased and very thankful for the continued participation and<br />

the great support of all the congress exhibitors and sponsors.<br />

Thanks to all participants, many have traveled far away from home, the fascination<br />

with proteomics is represented by the great attendance of this congress, as we have<br />

experienced in past HUPO congresses that are attended by delegates from over 50<br />

different countries. I also extend my sincere greetings to all the funding agencies<br />

and their representatives who are helping shape and define proteomics, its goals and<br />

objectives and in particular are in full support of HUPO and its activities.<br />

Whether you are attending the congress to share information, to learn, to discover new<br />

technologies, to seek collaborations, to be involved, or to simply have the opportunity<br />

to network with scientists of similar interests, I trust that you will find that HUPO’s<br />

passion to the field of proteomics and its commitment to bring the best science to<br />

its congress will help you achieve your goal and will re-confirm that the HUPO Annual<br />

Congress is a must for you and your colleagues throughout the World.<br />

Enjoy your stay in the wonderful city of Amsterdam and hope to see you in Toronto<br />

next year for HUPO 8th Annual World Congress September 26-30, 2009.<br />

Acknowledgements<br />

MAIN sponsors<br />

Elite sponsor HUPO Scientific initiatives<br />

exhibitors<br />

Rolf Apweiler<br />

HUPO President<br />

The 7th HUPO Annual World Congress expresses its warm thanks to our Exhibitors<br />

for supporting the Congress. We encourage all Congress Delegates to visit the<br />

Exhibition and to learn more about the products and services. The Exhibition is located<br />

in Exhibition Hall 10. Please consult the Floor plan.<br />

The exhibitors contact details are listed on pages 167-174.<br />

4 5


Committees<br />

Congress Chairs<br />

Albert Heck<br />

The Netherlands Proteomics Centre<br />

Utrecht University, The Netherlands<br />

Anne-Claude Gavin<br />

EMBL Heidelberg, Germany<br />

Ruedi Aebersold<br />

ETH Zurich<br />

University of Zurich, Switzerland<br />

Institute for Systems Biology, Seattle, USA<br />

Endorsed by<br />

Human Proteome Organisation<br />

www.hupo.org<br />

Netherlands Proteomics Centre<br />

www.netherlandsproteomicscentre.nl<br />

Executive Organizing Committee<br />

Werner Most<br />

Netherlands Proteomics Centre<br />

Silvie Hermsen<br />

Netherlands Proteomics Centre<br />

Wehbeh Barghachie<br />

HUPO Director of Operations<br />

HUPO Executive Committee<br />

Rolf Apweiler<br />

President<br />

Catherine Fenselau<br />

Senior VP<br />

Young-Ki Paik<br />

VP<br />

John Bergeron<br />

Past President<br />

Richard Simpson<br />

Treasurer<br />

Peipei Ping<br />

Secretary General<br />

Mathias Uhlén<br />

Member at Large<br />

European Proteomics Association<br />

www.eupa.org<br />

Congress Secretariat<br />

International Conference Services BV<br />

P.O. Box 14645<br />

1001 LC Amsterdam<br />

The Netherlands<br />

Tel: +31 (0)20 679 32 18<br />

Fax: +31 (0)20 675 82 36<br />

Email: hupo2008@ics-online.nl<br />

www.hupo2008.com<br />

Session Chairs & Pre-Congress Organisers<br />

The Congress Organization wishes to thank all those who have been actively involved<br />

in the organization of the Scientific Program as pre-congress program organizer or<br />

session chair. Their involvement is highly appreciated and has greatly contributed to<br />

the quality of the final program.<br />

6 7


Awards<br />

HUPO Discovery in Proteomic Sciences award:<br />

Catherine Costello<br />

HUPO Distinguished Service Award:<br />

Richard Simpson<br />

HUPO Distinguished Achievement Award in Proteomic Sciences:<br />

This Award is Sponsored by Journal of Proteome Research & ACS<br />

Denis Hochstrasser and Matthias Mann<br />

HUPO Young Investigator Awards:<br />

Jesper Olsen<br />

Shabaz Mohammed<br />

Adriana Paes Leme<br />

EuPA Senior Scientist Award in Proteomic Sciences:<br />

Stellan Hjerten<br />

EuPA Ph.D. Award Nominees:<br />

Bernd Bodenmiller<br />

Simone Lemeer<br />

Anissa Sidibe<br />

Tine E. Thingholm<br />

Leonie Waanders<br />

We thank the 2008 sponsors of student travel awards:<br />

Genome Canada Travel Awards to Canadian Students<br />

Hoffmann – La Roche AG Travel Awards<br />

Congress Related Meetings<br />

(on invitation only)<br />

HUPO Industry Advisory Board Meeting<br />

Sunday 17 <strong>August</strong><br />

Room L - 09.00 - 12.00 hrs<br />

Education Committee Meeting<br />

Sunday 17 <strong>August</strong><br />

Room P - 09.00 - 11.00 hrs<br />

HUPO Council Meeting<br />

Sunday 17 <strong>August</strong><br />

Room CD - 13.30 - 18.00 hrs<br />

Press Conference<br />

Monday 18 <strong>August</strong><br />

Room H - 12.30 - 14.00 hrs<br />

Regional HUPO Presidents’ Breakfast Meeting<br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />

Room P - 07.00 - 07.55 hrs<br />

Editorial Board meeting “Journal of Proteomics” (Elsevier)<br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />

Café Amsterdam - 12.30 - 14.00 hrs<br />

US HUPO Board Meeting<br />

Wednesday 20 <strong>August</strong><br />

Room P - 12.00 - 13.30 hrs<br />

Poster Viewing<br />

Posters will be on display in the exhibition and poster area (Hall 10 of the RAI Convention<br />

Centre). Each day posters can be viewed during meeting breaks which are scheduled<br />

daily on the following hours:<br />

Morning break<br />

Lunch break<br />

Afternoon break<br />

09.30 - 11.00 hrs<br />

12.30 - 14.00 hrs<br />

15.30 - 16.00 hrs<br />

We would like to ask all poster presenters to be present at their poster at least<br />

during the morning and afternoon break. All posters will be on display for one day only,<br />

either on Monday, <strong>Tuesday</strong> or Wednesday. Posters will be numbered as P-MON-#,<br />

P-TUE-# and P-WED-# respectively (see pages 68 – 157).<br />

8 9


Corporate Workshops<br />

QIAGEN<br />

07.00 - 07.50 hrs, room CD<br />

Tickets to be collected at booth 71<br />

Protein and peptide analysis from clinical specimens<br />

Kerstin Steinert, Director R & D, QIAGEN GmbH, Hilden, Germany<br />

Udo Roth, R & D Scientist, QIAGEN GmbH, Hilden, Germany<br />

Direct analysis of peptides in body fluids<br />

Hepcidin is the key regulator of iron metabolism and its concentration in urine provides<br />

diagnostic value in diseases. We present a new technique overcoming current hepcidin<br />

quantification issues by MALDI-MS in combination with sample preparation on-chip.<br />

Hepcidin detected directly in crude urine enables the establishment of HTP quantification<br />

workflows of this peptide.<br />

Standardized sample preparation from different tissues<br />

Huge numbers of Formalin-Fixed Paraffin-Embedded (FFPE) are prepared per year.<br />

Previously, due to the crosslinks formed during the fixation process, their analysis<br />

was limited to histochemical techniques. Here we present a method enabling efficient<br />

extraction of full-length proteins suitable for analysis of specific protein targets or<br />

proteomic approaches.<br />

PROMEGA CORPORATION<br />

07.00 - 07.50 hrs, room EF<br />

Tickets to be collected at booth 42<br />

breakfast workshops<br />

ProteasMAX Surfactant<br />

Improve Overall Confidence in Protein Identification<br />

Incomplete solubilization, digestion and poor peptide recovery are limitations in protein<br />

sample preparation for MS analysis. ProteasMAX Surfactant reduces these<br />

limitations while avoiding negative effects observed with common solubilizing agents.<br />

In-gel digestion showed up to 1.8-fold increase in protein coverage and up to 6.9-fold<br />

increase in MASCOT score.<br />

Monday, 18 <strong>August</strong><br />

AGILENT TECHNOLOGIES<br />

12.30 - 14.00 hrs, room B<br />

Tickets to be collected at booth 32<br />

Agilent’s HPLC-Chip/LC-MS:<br />

A key enabling technology for integrated proteomics workflows<br />

HPLC-Chip/LC-MS sits at the center of an integrated proteomics workflow from<br />

sample preparation to data analysis, encompassing identification and characterization,<br />

biomarker discovery and quantitation. We discuss the new HPLC-Chip 6530 Accurate<br />

Mass Q-TOF for more confident protein identification and the HPLC-Chip / 6460 Triple<br />

Quadrupole for sensitive targeted peptide quantitation. Leading scientists will present<br />

applications using the innovative HPLC-Chip/MS technology.<br />

APPLIED BIOSYSTEMS /<br />

MDS ANALYTICAL TECHNOLOGIES<br />

12.30 - 14.00 hrs, room CD<br />

Tickets to be collected at booth 63<br />

Increasing Throughput and Quality of Results in Protein Biomarker Discovery<br />

and Verification<br />

Increasing throughput can often mean compromising the quality of data and results.<br />

Innovations from Applied Biosystems/MDS Analytical Technologies break this paradigm<br />

and actually increase the quality of results along with increasing sample throughput.<br />

This workshop will discuss how advances in MS systems, <strong>software</strong>, reagents and<br />

workflows enable new levels of protein biomarker productivity.<br />

BRUKER DALTONICS<br />

12.30 - 14.00 hrs, room EF<br />

Tickets to be collected at booth 22<br />

lunch workshops<br />

(R)evolution in Label-free Proteomics and Data Evaluation<br />

A prestigious researchers’ panel will present talks detailing a series of innovative applications<br />

utilizing the maXis for protein identification and quantitation with accurate<br />

mass, ultra high resolution across a broad mass range, high sensitivity, all at the high<br />

speed needed to take full advantage of ultra-high performance liquid chromatography.<br />

10 11


Corporate Workshops<br />

ROSETTA BIOSOFTWARE<br />

07.00 - 07.50 hrs, room B<br />

Tickets to be collected at booth 85<br />

Real-World Proteomics:<br />

A Spectrum of Workflows in the Rosetta Elucidator System<br />

Presented by Tim Bonnert, Ph.D. Rosetta Bio<strong>software</strong> & Hendrik Neubert, Ph.D.<br />

Pfizer Global Research and Development<br />

The diversity of scientific questions that are being addressed by LC/MS proteomics<br />

necessitates a varied approach to experimental design and execution. Data could be<br />

generated on multiple high- or low-resolution instruments as label-free or labelled (e.g.<br />

SILAC, or ICAT) samples using 1D- or multidimensional separation in data dependent,<br />

data independent (MS(E)) or targeted MS/MS modes. Such diverse methods of<br />

data generation may also benefit from multiple database search engines and diverse<br />

statistical, analytical, and visualisation methods.<br />

The Rosetta Elucidator® system (www.rosettabio.com/elucidator) provides a<br />

comprehensive solution for the rapid and efficient analysis of any number of samples<br />

collected by any of these workflows. This seminar will showcase a number of different<br />

LC/MS workflows and will also discuss how LC/MALDI offers several benefits over the<br />

more conventional LC/ESI methodology (see Neubert et al. J Proteome Res. 2008, 7,<br />

pp2270-9)<br />

GE HEALTHCARE EUROPE<br />

07.00 - 07.50 hrs, room CD<br />

Tickets to be collected at booth 52<br />

breakfast workshops<br />

Quantitative solutions in proteomics:<br />

A novel use of Ettan DIGE fluorescent cye dyes and 2D LC<br />

This GE Healthcare seminar will introduce an exciting and new technique, combining a<br />

novel dual labelling strategy with 2D LC. Samples are labeled at the protein level with<br />

both Ettan DIGE fluorescent cye dyes and stable isotope labels (ICPL), prior to 2D LC.<br />

Quantitation is performed at both the protein and peptide level. This method addresses<br />

important issues such as loading capacity, dynamic range, sample complexity and<br />

relating peptide signals to parent protein origin.<br />

<strong>Tuesday</strong>, <strong>19</strong> <strong>August</strong><br />

THERMO SCIENTIFIC<br />

12.30 - 14.00 hrs, room B<br />

Tickets to be collected at booth 34<br />

Thermo Fisher Scientific cordially invites you to attend an educational workshop on the<br />

latest integrated solutions for protein characterization and quantitation featuring the<br />

following two talks:<br />

Driving Biological Discovery using the LTQ Orbitrap<br />

John Yates, Ph.D. - The Scripps Research Institute - Department of Cell Biology<br />

First Impressions of the MALDI LTQ Orbitrap<br />

Michael Karas, Ph.D.<br />

Institute for Pharmaceutical Chemistry - Goethe University, Frankfurt am Main<br />

DIONEX CORPORATION<br />

12.30 - 14.00 hrs, room CD<br />

Tickets to be collected at booth 61<br />

Approaches for High Resolution 2-D LC/MS in Proteomics<br />

Multidimensional liquid chromatography provides high resolution identification of<br />

proteins by MS/MS; including scarce and difficult to separate proteins, and is gaining<br />

popularity over traditional 2-D electrophoresis. Dionex recently introduced a new<br />

proteomics MDLC platform. This workshop will review automation and optimization of<br />

MDLC methods for top-down and bottom-up protein identification.<br />

BRUKER DALTONICS<br />

12.30 - 14.00 hrs, room EF<br />

Tickets to be collected at booth 22<br />

(R)evolution in Top Down Analysis and PTM Discovery<br />

Presented will be an overview of recent proteomics application:<br />

MALDI-TDS for novel Top-Down Sequencing providing 100% protein sequence<br />

coverage incl. C- / N- terminal assignments,<br />

ETD/PTR for PTM and intact protein analysis in the HCTultra ion trap<br />

high performance MALDI tissue imaging using the SmartBeam proprietary laser<br />

PROMEGA CORPORATION<br />

12.30 - 14.00 hrs, room P<br />

Tickets to be collected at booth 42<br />

lunch workshops<br />

HaloLink Protein Arrays for Functional Proteomics<br />

Promega’s HaloLink protein arrays allow rapid creation of arrays on demand. HaloTag®<br />

fusion bait proteins expressed in vitro or in vivo are covalently bound to a glass slide<br />

through our proprietary HaloTag® linkage. Bait proteins can be captured directly from<br />

lysate or reaction mix without prior purification, leading to rapid, parallel and multiplex<br />

analysis of protein interactions.<br />

12 13


Corporate Workshops<br />

ROSETTA BIOSOFTWARE<br />

07.00 - 07.50 hrs, room B<br />

Tickets to be collected at booth 85<br />

The Analysis of Diagnostic Markers For Lysosomal Storage Disorders:<br />

A Case Study in Label-Free Differential Analysis in the Rosetta Elucidator System<br />

Presented by Cindy Chepanoske, Ph.D. Rosetta Bio<strong>software</strong><br />

The Rosetta Elucidator® system (www.rosettabio.com/elucidator) provides a<br />

comprehensive solution for the rapid and efficient analysis of LC/MS data from multiple<br />

instruments and workflows. Multi-instrument support by the Elucidator system has<br />

been further expanded by the integration of Waters® Ultra Performance LC/MS(E)®<br />

proteomics discovery data and results from the Identity(E) search engine, so that data<br />

produced on Waters’ instrumentation can be analyzed using the Elucidator <strong>software</strong>.<br />

Gaucher disease is the most common lysosomal storage disease and there is great<br />

clinical interest to identify and quantify additional biomarkers for this disease. A labelfree<br />

LC/MS(E) serum profiling analysis was conducted to quantitatively characterize<br />

candidate biomarkers. The workflow used for biomarker discovery in the Elucidator<br />

system will be presented, followed by a live demonstration of the <strong>software</strong>.<br />

GE HEALTHCARE EUROPE<br />

07.00 - 07.50 hrs, room CD<br />

Tickets to be collected at booth 52<br />

Biacore analysis – exploring the real-time world of protein interactions<br />

Speaker: Erik Verschuuren<br />

breakfast workshops<br />

Biacore systems for label-free interaction analysis provide information on binding<br />

specificities, affinities and kinetics, as well as interactant concentrations. This<br />

presentation will exemplify how Biacore systems are used to validate, quantify,<br />

and characterize protein interactions to unravel the mechanisms behind cellular<br />

processes.<br />

Wednesday, 20 <strong>August</strong><br />

THERMO SCIENTIFIC<br />

07.00 - 07.50 hrs, room EF<br />

Tickets to be collected at booth 34<br />

Thermo Fisher Scientific cordially invites you to attend an educational workshop on the<br />

latest integrated solutions for protein characterization and quantitation featuring the<br />

following two talks:<br />

Approaches to global phosphoproteomic analysis<br />

Nick Morrice, Ph.D.<br />

MRC Protein Phosphorylation Unit<br />

University of Dundee<br />

Absolute quantification of targeted endogenous salivary peptides using heavy<br />

isotope-labeled synthetic internal standards and high resolution selected reaction<br />

monitoring mass spectrometry<br />

Markus Hardt, Ph.D.<br />

University of California, San Francisco<br />

Department of Cell and Tissue Biology<br />

WATERS<br />

12.30 - 14.00 hrs, room B<br />

Tickets to be collected at booth 60<br />

The next generation of proteomics technology;<br />

Combining novel nanoscale separations with high-performance mass spectrometry<br />

This seminar will focus on new separation and mass spectrometry techniques that can<br />

be applied to proteomics research. We will detail the development and application of<br />

the TRIZAIC® nanoACQUITY UPLC proteomics system, and the Xevo TQ MS, a novel<br />

tandem quadrupole LC-MRM system.<br />

BIO-RAD LABORATORIES<br />

12.30 - 14.00 hrs, room CD<br />

Tickets to be collected at booth 90<br />

Technologies for Biomarker Discovery<br />

lunch workshops<br />

With the right technologies, the challenges of Biomarker discovery can be minimized.<br />

ProteoMiner technology reduces sample complexity, allowing you to dig deeper in the<br />

proteome. 2-DGE and SELDI enable the detection of changes in protein levels and<br />

potential biomarker candidates. Data generated with these technologies demonstrates<br />

their power for Biomarker discovery.<br />

14 15


INVITROGEN<br />

12.30 - 14.00 hrs, room EF<br />

Tickets to be collected at booth 108<br />

Discovery of SLE Autoantibody Biomarkers using Protein Microarray Technology &<br />

Protein Sample Purification and Fractionation using Dynabeads Magnetic beads<br />

The diagnostic value of serum autoantibodies for many diseases, including cancer,<br />

diabetes, and autoimmune disorders is well established. Realizing the promise of<br />

autoantibody panels in diagnosis, prognosis and treatment response predictions will<br />

require the use of multiplex tools that enable investigators to query the autoantibody<br />

profile on a proteomic scale. Identifying the antigens that elicit an autoimmune<br />

response can yield panels of biomarkers that can be used as classifiers for particular<br />

diseases, disease stages, or as predictors of patient outcomes. The present study<br />

utilized high content functional protein microarrays comprised of >8,000 purified fulllength<br />

human proteins, including a panel of >20 annotated autoantigens. These protein<br />

microarrays were probed with serum from Systemic Lupus Erythematosus (SLE)<br />

patients and compared with serum from disease-free donors. Patient serum from<br />

other autoimmune disorders (RA, vasculitis) were included to identify SLE-specific<br />

markers rather than autoimmune-specific. Statistical algorithms were developed to<br />

analyze data from individual microarrays and to compare data between populations. This<br />

line of investigation identified a panel of 18 novel biomarkers which could differentiate<br />

SLE patients from healthy individuals more accurately than a panel of 10 established<br />

SLE biomarkers. Validation studies utilizing the Luminex platform were used to confirm<br />

the results obtained via the ProtoArray. Taken together, our results suggest that<br />

functional protein microarray technology is a powerful new tool for the rapid discovery<br />

of autoantigen biomarkers.<br />

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1<br />

1 2 1<br />

3 2 2<br />

4 3 3<br />

5 4 4<br />

6 5 5<br />

7 6<br />

8 7<br />

8<br />

9<br />

9<br />

WHO & WHERE?<br />

Node 4 Associate<br />

F.J. Blanco - H J.Canalejo<br />

Node 4<br />

X. Bustelo - CIC<br />

*<br />

Node 2<br />

J. Mato - CIC-bioGUNE<br />

F. Corrales - CIMA<br />

JM. Arizmendi - UPV<br />

Node 3<br />

J. Abián - LP-CSIC/UAB<br />

J. Arribas - HUVH<br />

S. Martínez - PCB<br />

D. Andreu - UPF<br />

FX. Avilés - IBB UAB<br />

O. Bachs - UB<br />

Central Structure<br />

JP. Albar - CNB<br />

JM. Mato - CIC-bioGUNE<br />

J. Abian - LP-CSIC/UAB<br />

*<br />

Overall Floor Plan Congress Venue<br />

Node 1<br />

JP. Albar - CNB<br />

C. Gil - PCM-UCM<br />

A. Marina - CBMSO<br />

I. Casal - CNIO<br />

J.M. Carazo - INB-CNB<br />

-<br />

Node 5 Associate<br />

P. Carrasco - UV<br />

Node 5<br />

M. S. del Pino - CIPF<br />

R. Bru - UA<br />

Room B<br />

HOW?<br />

Node 1 Associate<br />

V. Ceña - UCLM<br />

Node 6<br />

JA. Bárcena - UCO<br />

Current Working Groups:<br />

WG 1. Technological development and<br />

standardization of protocols.<br />

WG 2. Samples collection and handling.<br />

WG 3. Bioinformatics support.<br />

WG 4. Functional organization of proteomic<br />

services and coordination of price scales.<br />

WG 5. Training, education and diffusion.<br />

WG 6. Internationalization and coordination<br />

with other proteomic consortia<br />

and platforms.<br />

WG 7. Biomedical Proteomics.<br />

XXXX<br />

Auditorium<br />

Room Auditorium<br />

Room C-D<br />

Room E-F<br />

www.proteored.org<br />

WHY?<br />

ProteoRed purpose is the coordination and integration of activities of the<br />

proteomics facilities to guarantee the access of the scientific comunity to<br />

the state-of-the-art proteomics technology.<br />

WHEN?<br />

ProteoRed is continously improving standards on its proteomics services,<br />

by incorporating HUPO-PSI guidelines and formats, since June 2005, setting<br />

a quality label for their users.<br />

WHAT?<br />

- Protein and Peptide Molecular Weight Analysis<br />

- Protein Identification<br />

- Characterization and Protein Modifications<br />

- Differential Proteomics<br />

- Sequencing<br />

- Peptide Synthesis<br />

- 2D electrophoresis<br />

- Bioinformatics Tools<br />

TOOLS<br />

MIAPEs Web templates:<br />

GE, GI, MS, MSI<br />

PRIDE schema tools:<br />

PIKE, Virtual 2D, PRIDE<br />

viewer, GARBAN, …<br />

spanish institute for proteomics .<br />

Room A<br />

Room Auditorium<br />

Room Forum Room L<br />

Forum<br />

i<br />

E E N N T E T R N R A T A N R N C A C E N E C E T O T O S T S E O E S S E I S O I S O N I N O R N O R O O M MS O S MS<br />

HALL 10<br />

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- 116<br />

Speaker Ready Room<br />

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posters posters 001<br />

- 060<br />

- 001 060 - 060<br />

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Waters<br />

52 Waters Waters<br />

52 52 I n t e r n e t<br />

I n t e r n e t<br />

C orner<br />

orner C orner<br />

Room N-N1-O1-O<br />

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a C t a e t r e i r n i g n g a r a e r a e a<br />

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1<strong>19</strong> 1<strong>19</strong> 118 118 115 115<br />

EE EE EE EE EE EE<br />

EXHIBITOR SERVICES<br />

EXHIBITOR SERVICES<br />

18 <strong>19</strong>


Floor Plan Exhibition Area<br />

List of Exhibitors<br />

Booth<br />

No.<br />

Organisation<br />

Booth<br />

No.<br />

Organisation<br />

EE<br />

EE<br />

HALL 10<br />

10<br />

51<br />

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Waters<br />

I n I t n e t r e n r e n t<br />

e t<br />

C orner<br />

C orner<br />

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posters 117 - 166<br />

posters 117 - 166<br />

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posters posters 061 061 - 116<br />

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posters posters 167 167 - 216<br />

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posters posters 001 001 - 060<br />

- 060<br />

E N E T N R T A R N A C N E<br />

C E<br />

T O T O S E S S E S I S O I N O R N O R R O MS O M O MSS<br />

M S<br />

C C a t a e t r e i r n i g n g a r a e r a<br />

e a<br />

posters posters 305 305 - 374<br />

- 374<br />

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posters posters 217 217 - 234<br />

- 234<br />

1<strong>19</strong><br />

1<strong>19</strong><br />

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118<br />

115 115<br />

EXHIBITOR SERVICES<br />

001 GL Sciences Inc.<br />

002 INTAVIS Bioanalytical Instruments<br />

003 JPT Peptide Technologies GmbH<br />

004 Proxeon<br />

005 Silantes GmbH<br />

006<br />

UVic Genome BC Proteomics<br />

Centre<br />

007 UVP<br />

008<br />

Australian Proteome Analysis<br />

Facility Ltd<br />

009<br />

Netherlands Genomics Initiative /<br />

Netherlands Proteomics Centre<br />

011 Pall Life Sciences<br />

012 GenWay Biotech, Inc.<br />

022 Bruker Daltonics<br />

023 Digilab Genomic Solutions (UK) Ltd<br />

025 Atlas Antibodies<br />

026 Sigma-Aldrich<br />

027 American Chemical Society<br />

030 Miltenyi Biotec<br />

031 Peaks<br />

032 Agilent Technologies<br />

034 Thermo Scientific<br />

037 Nonlinear Dynamics<br />

040 Syngene<br />

042 Promega Corporation<br />

044 Caprotec Bioanalytics GmbH<br />

045 PSS Europe GmbH<br />

046 Epitomics, Inc.<br />

047<br />

EMBL-European Bioinformatics<br />

Institute<br />

051 Nanoxis AB<br />

052 GE Healthcare Europe GmbH<br />

060 Waters<br />

061 Dionex Corporation<br />

063<br />

Applied Biosystems / MDS<br />

Analytical Technologies<br />

066 R & D Systems Europe<br />

068 SERVA Electrophoresis GmbH<br />

070 Abfrontier Co. Ltd<br />

071 Qiagen<br />

072 Denator AB<br />

073 Dualsystems Biotech AG<br />

074<br />

EuPA / The Swedish Academy of<br />

Pharmaceutical Sciences<br />

075 HUPO 2009<br />

076 HUPO HQ<br />

078 Elsevier<br />

079 Science International / AAAS<br />

080 BD Diagnostics<br />

082 BD Biosciences<br />

083 CovalX AG<br />

084 Eksigent Technologies<br />

085 Rosetta Bio<strong>software</strong><br />

086 Protein Forest Inc<br />

087 Ludesi AB<br />

090 Bio-Rad Laboratories<br />

092 Shimadzu<br />

100 GenoLogics<br />

101 Decodon<br />

102 Hoefer, Inc<br />

103 Genebio Geneva Bioinformatics<br />

104 Axela Inc.<br />

105 IOS Press<br />

107<br />

Merck / EMD,<br />

Novagen & Calbiochem<br />

108 Invitrogen / Dynal<br />

110 Labcyte Inc.<br />

111 RSC Publishing<br />

115 Aushon BioSystems<br />

118 Pressure BioSciences, Inc.<br />

1<strong>19</strong> Wiley-VCH Verlag<br />

20 21


ty Number 207890<br />

ISSN 1742-206X<br />

11/07/2007 09:34:16<br />

es<br />

tions by<br />

cement<br />

eir<br />

the<br />

Paris,<br />

Image reproduced by permission of A. Manz, Lab Chip 2006, 6(4)<br />

t more<br />

erprize<br />

Research at the interface between<br />

chemistry, the –omic sciences and<br />

systems biology<br />

14020750<br />

Volume 3 | Number 8 | 2007 Molecular BioSystems Pages 509–568<br />

Molecular<br />

BioSystems<br />

www.molecularbiosystems.org Volume 3 | Number 8 | <strong>August</strong> 2007 | Pages 509–568<br />

HIGHLIGHT<br />

Diane M. Ramos and Antónia Monteiro<br />

Transgenic approaches to study<br />

wing color pattern development in<br />

Lepidoptera<br />

METHOD<br />

K. Imai, Y. Ogai, D. Nishizawa, S. Kasai,<br />

K. Ikeda and H. Koga,<br />

A novel SNP detection technique<br />

utilizing a multiple primer extension<br />

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surface<br />

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*2007 Thomson Scientific (ISI) Journal Citation Reports ®<br />

www.molecularbiosystems.org<br />

Registered Charity Number 207890<br />

08080727a<br />

Saturday 16 <strong>August</strong> 2008<br />

location <br />

Exhibition hall 10 Room Forum Room A Room B Room CD Room EF<br />

time <br />

whole day Exhibition build-up Educational Day<br />

HUPO<br />

Human Proteome<br />

Project I<br />

09.30 - 12.30<br />

Educational Day<br />

Session I<br />

09.30 - 12.00<br />

HUPO<br />

Human Antibody Initiative<br />

HUPO<br />

Liver Proteome<br />

Project<br />

HUPO<br />

Brain Proteome Project<br />

HUPO<br />

Proteome Biology of Stem<br />

Cells Initiative<br />

14.00 - 17.30<br />

Educational Day<br />

Session II<br />

14.30 - 17.00<br />

Model Organisms<br />

Workshop<br />

HUPO Human<br />

Kidney and Urine<br />

Proteome Project<br />

HUPO<br />

Human Proteome<br />

Project II<br />

18.30 - 21.00<br />

Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />

= Initiative = Other meeting<br />

22 23


Saturday 16 <strong>August</strong><br />

hupo educational day<br />

09.30 - 12.30 Educational Day Session i room: Forum<br />

Welcome Address<br />

Angelika Görg and Ole Jensen<br />

Gel-based Proteomics<br />

Angelika Görg<br />

Sample Preparation and Protein Detection Thierry Rabilloud<br />

Shot gun Proteomics<br />

Mike MacCoss<br />

Antibodies<br />

Mathias Uhlén<br />

14.00 - 17.30 Educational Day Session II<br />

Welcome Address<br />

Angelika Görg and Ole Jensen<br />

hupo initiatives program<br />

HUPO Human Proteome Project I Workshop<br />

room: A<br />

09.30 - 12.00<br />

Chairs: John Bergeron and Mathias Uhlén<br />

Introduction<br />

John Bergeron<br />

The Human Proteome; where are we now Matthias Mann<br />

One gene -<br />

Ruedi Aebersold<br />

one (or sufficient) proteotypic peptide(s)<br />

One gene – one antibody<br />

Mathias Uhlén<br />

Speed and Dynamic Range;<br />

John Yates<br />

bottle necks in mass spectrometry<br />

Post-translational modifications and Albert Heck<br />

protein processing<br />

and Alan Sawyer, Fredrick Ponten, Jack Greenblatt, Rolf Apweiler, Marty McIntosh,<br />

Tommy Nilsson, Young-Ki Paik, Giulio Superti-Furga and Anne-Claude Gavin.<br />

Mass Spectrometry<br />

Mass Spectrometry based Quantification<br />

Post-translational Modifications<br />

Roman Zubarev<br />

Shabaz Mohammed<br />

Ole Jensen<br />

Mass Spectrometry related Bioinformatics<br />

Session I;<br />

Comparison of search engines<br />

Bas van Breukelen<br />

Session II;<br />

Pierre-Alain Binz<br />

Standards for data-sharing and available resources and databases for metaannotation<br />

of proteomics<br />

24 25


HUPO Proteome Biology of Stem Cells Initiative Workshop<br />

14.30 - 17.00<br />

Chairs: Jeroen Krijgsveld and Albert Heck<br />

room: A<br />

14.30 The HUPO PBSCI: Where are we now<br />

Jeroen Krijgsveld, Utrecht University, The Netherlands<br />

14.40 Quantitative proteomics of embryonic stem cell differentiation<br />

Tony Whetton, University of Manchester, Manchester, UK<br />

14.55 Phosphorylation dynamics during differentiation of embryonic stem cells<br />

Javier Muñoz, Utrecht University, The Netherlands<br />

15.10 In-depth quantitation of the mouse ES cell proteome<br />

15.25<br />

Nina Hubner, Max Planck Institute for Biochemistry, Martinsried, Germany<br />

Quantification of early signaling <strong>event</strong>s in embryonic stem cell self-renewal<br />

Jarrod Marto, Harvard Medical School, Boston, USA<br />

15.40 Comparative proteome an transcriptome analysis of human, mouse<br />

and monkey ESCs during differentiation<br />

Ghasem Hosseini Salekdeh, Royan Institute, Tehran, Iran<br />

15.55<br />

16.15<br />

Break<br />

Discussion<br />

HUPO Brain Proteome Project Workshop<br />

14.30 - 17.00<br />

Chairs: Helmut E. Meyer, Michael Hamacher & Young Mok Park<br />

room: B<br />

In this workshop, colleagues will present new, innovative analysis strategies for study<br />

pathomechanisms of different neurodegenerative diseases.<br />

14.30 Welcome address & Update: Barbados Wish List<br />

Helmut E. Meyer & Michael Hamacher (MPC, GER)<br />

14.50 Proteinbiochips<br />

Helmut E. Meyer (MPC, GER)<br />

15.30 The balancer concept<br />

Joachim Klose (Charité, GER)<br />

16.00 Neuropathology<br />

Lea Grinberg (Sao Paolo, BR)<br />

16.30 Oral from Poster Session<br />

N.N. (N.N., N.N)<br />

16.50 General Discussion & End of Session<br />

Young Mok Park (KBSI, KOR) & All<br />

HUPO Liver Proteome Project Workshop<br />

room: CD<br />

14.30 - 17.00<br />

Chair: Laura Beretta<br />

Co-chairs and session leaders: John Bergeron, Young-Ki Paik, Chantal Housset,<br />

Xiaohong Qian<br />

Participants: Rolf Apweiler, Pengyuan Yang, Siqi Liu, Gil Omenn, Eric Deutsch,<br />

Lennart Martens, Paul Boersema, Ying Jiang<br />

Introduction<br />

The Human Proteome Project: The Liver Perspective<br />

mass spectrometry - based coverage / where are we now<br />

antibody - based coverage / resources, integration, complementarity<br />

localization, abundance and liver tissue specificity<br />

pilot projects<br />

towards a mouse proteome project<br />

Comparative Analysis Of The Liver And Plasma Proteomes<br />

proteins and glycoproteins<br />

peptides<br />

abundance<br />

Opportunities For The Study Of Liver Diseases Within Hlpp<br />

data repository<br />

liver disease biomarkers: a focus on liver cancer<br />

biobanks and mouse models<br />

5th HUPO Human Antibody Initiative Workshop R<br />

14.30 - 17.00<br />

Chair: Mathias Uhlén<br />

Welcome and introduction<br />

Snyder, Hudson, Uhlén<br />

Short update on the Human Protein Atlas Ponten, UU, Sweden<br />

Update on antibodies<br />

A. Mono-specific antibodies Hober, KTH, Sweden<br />

B. Monoclonal antibodies Sawyer, Monash, Australia<br />

Update on recombinant affinity reagents<br />

A. Introduction Hudson, Australia<br />

B. New strategies for selection Weiner, USA<br />

C. Array strategies for selection Borrebeack, Sweden<br />

Pilot projects for antibody generation<br />

A. Cancer related proteins Rodriguez, NCI, US<br />

B. SH2 domains Graslund, KI, Sweden<br />

C. Chromosome 21 genes Berglund, KTH, Sweden<br />

D. ProteomeBinder Taussig, Cambridge, England<br />

Antibodypedia - portal for validated antibodies<br />

A. Update of portal Bjorling, KTH, Sweden<br />

B. Standards for affinity reagents Hermjacob, EBI, England<br />

Discussions<br />

Snyder, Hudson and Uhlén<br />

A. Pilot projects and antibodypedia<br />

B. How to relate to a Human Proteome Project<br />

room: EF<br />

26 27


HUPO Human Proteome Project II Workshop<br />

18.30 - 21.00<br />

Chair: Rolf Apweiler<br />

Invitees: Funding agencies and Proteomics leaders<br />

Program to be announced<br />

HUPO Human Kidney and Urine Proteome Project<br />

18.30 - 21.00<br />

Session chair: Tadashi Yamamoto, Niigata University, Japan<br />

18.30 - 18.35<br />

Introduction<br />

Tadashi Yamamoto<br />

Chair of HKUPP, Niigata University, Japan<br />

room: A<br />

room: B<br />

18.35 - 20.20 Session 1<br />

Standards and Guidelines for Proteome Analysis of Non-Proteinuric Urine<br />

Co-chairs: Tadashi Yamamoto (Niigata University, Japan) and Antonia Vlahou<br />

(Biomedical Research Foundation of the Academy of Athens, Greece)<br />

18.35 - <strong>19</strong>.20 Summary of previous studies and discussion<br />

Visith Thongboonkerd<br />

Medical Molecular Biology Unit, Office of Research and Development, Faculty of Medicine,<br />

Siriraj Hospital, Mahidol University, Bangkok, Thailand<br />

<strong>19</strong>.20 - <strong>19</strong>.32 Different urine desalting methods and their impact on 2D<br />

gel electrophoresis quality and protein identification<br />

Hassan Dihazi<br />

Clinical Proteomics Laboratories, Nephrology and Rheumatology, Georg-<strong>August</strong> University<br />

Goettingen, Goettingen, Germany<br />

<strong>19</strong>.32 - <strong>19</strong>.44 CE-MS based human urinary proteome database for<br />

biomarker discovery and disease diagnosis<br />

Petra Zürbig 1 , David M. Good 2 , Eric Schiffer 1 , Joshua J. Coon 2, 3<br />

and Harald Mischak 1<br />

1<br />

Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany<br />

2<br />

Department of Chemistry<br />

3<br />

Department of Biochemistry, University of Wisconsin University of Wisconsin-Madison,<br />

Madison, WI, USA,<br />

<strong>19</strong>.44 - <strong>19</strong>.56 Urinary proteomic biomarkers in coronary artery disease<br />

Eric Schiffer 1 , Lukas U. Zimmerli 2 , Janet K. Snell-Bergeon 3 ,<br />

David M. Maahs 3 , Harald Mischak 1 , and Anna F. Dominiczak 4<br />

1<br />

Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany<br />

2<br />

Division of Internal Medicine, University Hospital Zurich, Zurich, Switzerland<br />

3<br />

Barbara Davis Center for Childhood Diabetes, Aurora, USA<br />

4<br />

BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.<br />

<strong>19</strong>.56 - 20.08 A novel, non-invasive multiplex-assay to diagnose acute<br />

rejection in the urine of renal transplant recipients.<br />

Diana Breuer 1 . Gerald Schlaf 1 , Wolfgang Altermann 1 , Barbara<br />

Selinger 1 , Paolo Fornara 2 and Amir Hamza 2<br />

1 Martin-Luther-University Halle –Wittenberg, Medical School, HLS-Laboratory (GHATT)<br />

2<br />

Department or Urology and Kidney Transplant Center<br />

20.08 - 20.20 Influence of acid mucopolysaccharide in proteome analysis<br />

of non-protein urine<br />

Zhinguo Li, Tingting Zhao, Liping Yang, Jingzhen Guo, and Ping Li<br />

Department of Pharmacology, Institute of Clinical Medical Science, China-Japan Friendship<br />

Hospital, Beijing, P.R. China<br />

20.20 - 20.40 Session 2<br />

New Activity of HKUPP<br />

Chair: Yutaka Yoshida (Niigata University, Japan)<br />

20.20 - 20.30 News from HUPO<br />

Tadashi Yamamoto<br />

Department of Structural Pathology, Institute of Nephrology, Graduate School of Medical<br />

and Dental Sciences, Niigata University, Niigata, Japan<br />

20.30 - 20.40 News from EuroKUP<br />

Antonia Vlahou<br />

Biomedical Research Foundation of the Academy of Athens, Athens, Greece<br />

20.40 - 21.00 Session 3<br />

Free Discussion<br />

Chair: Visith Thongboonkerd (Mahidol University, Bangkok, Thailand)<br />

Model Organisms Workshop<br />

room: CD<br />

18.30 - 21.00<br />

Chairs: Michael Hengartner, Ruedi Aebersold, Sabine Schrimpf<br />

Invitees: Matthias Mann, Steven Gygi, Albert Heck, Young-Ki Paik, Rolf Apweiler, Klaas<br />

van Wijk, Richard Smith, Lennart Markus, Mike McCoss, Steven Briggs, Phil Andrews<br />

18.30<br />

18.50<br />

<strong>19</strong>.10<br />

How to compile proteomes reliably<br />

Matthias Mann<br />

How to analyze data and how to make the data accessible and<br />

exchangeable efficiently<br />

Alexey I. Nesvizhskii<br />

How to make the data accessible and exchangeable efficiently<br />

Ruedi Aebersold<br />

The following discussion until 21.00 will be about the possibility/necessity/organization<br />

of a new HUPO initiative in “model organism proteomes”.<br />

28 29


Solutions for protein stabilization, separation,<br />

purification, and analysis<br />

Stop by BD Booth 80<br />

to learn more about<br />

our proteomics offering:<br />

BD P100 and P700 Blood Collection Tubes –<br />

stabilize plasma proteins for biomarker<br />

discovery and metabolic studies<br />

BD FFE – obtain high resolution separation<br />

and purification of proteins, peptides<br />

and cell organelles<br />

Phosflow – multiplexed activation-state<br />

analysis of rare cell types in complex primary<br />

samples and simultaneous correlation of<br />

multiple phosphorylation <strong>event</strong>s<br />

For more information visit:<br />

www.bd.com/proteomics<br />

www.bdphosflow.com<br />

Visit BD<br />

at Booth<br />

80<br />

BD Diagnostics<br />

Preanalytical Systems<br />

1 Becton Drive<br />

Franklin Lakes, NJ 07417<br />

Sunday 17 <strong>August</strong> 2008<br />

location <br />

Exhibition hall 10 Room Forum Room A Room B Room CD Room EF<br />

time <br />

whole day Exhibition build-up Clinical Day<br />

HUPO<br />

Plasma Proteome<br />

Initiative<br />

HUPO<br />

Proteomics Standards<br />

09.00 - 12.00<br />

HUPO Cardiovascular<br />

Proteome Initiative<br />

HUPO<br />

Glycomics Initiative<br />

Workshop<br />

09.00 - 12.25<br />

Clinical Day<br />

Session I<br />

09.30 - 12.00<br />

Clinical Day<br />

Session II<br />

13.30 - 17.30<br />

18.30 - 21.00<br />

Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />

= Initiative = Other meeting<br />

BD, BD Logo and all other trademarks are property of Becton, Dickinson and Company. © 2008 BD<br />

30 31


Sunday 17 <strong>August</strong><br />

Biomarkers from Discovery to Clinical Application,<br />

Industry & Academia Views<br />

09.00 - 17.30<br />

room: Forum<br />

09.00 - 10.20 Biomarker Discovery & Implementation Perspectives<br />

09.00 - 09.40 Victor Jongeneel, Vice President for Research,<br />

The Cyprus Institute in Nicosia, Cyprus<br />

09.40 - 10.20 The Road to Diagnostic Proteomics: How far have we come?<br />

Sudhir Srivastava, NCI, Bethesda, USA<br />

10.20 - 10.40<br />

Coffeebreak<br />

10.40 - 12.25 Biomarkers for Heart, Liver & Pregnancy<br />

10.40 - 11.15 Heart disease biomarkers<br />

Hendrik Milting, Heart Centre, Bad Oeynhausen, Germany<br />

11.15 - 11.50 New biomarkers related to Preeclampsia<br />

Thomas Brinkmann, Beckman Coulter<br />

11.50 - 12.25 Discovery & Validation of Liver Biomarkers<br />

Kai Stuehler, Medizinisches Proteom-Center, Bochum, Germany<br />

12.25 - 13.30<br />

Lunch break on-site<br />

13.30 - 15.30 Biomarkers for Brain & Kidney Diseases<br />

13.30 - 14.00 Brain Stroke Biomarker Discovery<br />

Jean-Charles Sanchez, Geneva, Switzerland<br />

14.00 - 14.30 “S100B - a biomarker for Brain injury”<br />

Susanne Grüb, Roche, Basel, Switzerland<br />

14.30 - 15.00 Protein Profiles as Biomarker for Kidney Diseases<br />

Harald Mischak, Mosaique Diagnostics, Hannover, Germany<br />

15.00 - 15.30 Autoimmune Antibodies as Biomarkers for<br />

Neurodegenerative Diseases<br />

Stefan Müllner, Protagen AG, Dortmund, Germany<br />

15.30 - 16.00<br />

Coffee break<br />

16.00 - 16.30 Glyco-Biomarkers for Cancer<br />

16.00 - 16.30 Glycoproteins as Cancer Biomarker<br />

Naoyuki Tanaguchi, Osaka University, Japan<br />

16.30 - 17.30<br />

hupo clinical day<br />

Panel Discussion<br />

Biomarker from Discovery to Clinical Application<br />

What is the right way to succeed?<br />

Panellists from Industry, Academy & Agencies<br />

hupo initiatives program<br />

HUPO Glycomics Initiative Workshop<br />

09.30 - 12.00<br />

Chairs: Naoyuki Taniguchi, James Paulson and Hisashi Narimatsu<br />

room: A<br />

09.30 - 09.35 Welcome and Introduction of HGPI and the pilot studies<br />

N. Taniguchi (Osaka University)<br />

09.35 - 10.00 Report on the second HGPI pilot study-Comparison of the<br />

methods for profiling glycoprotein O-glycans<br />

S. Haslam and A. Dell (Imperial College)<br />

10.00 - 10.15 Glycan structural analysis of glycoproteins using O-linked<br />

glycan libraries<br />

H. Ito and H, Narimatsu<br />

(Advanced Institute for Science and Technology)<br />

10.15 - 10.30 Increased sensitivity in the profiling of mucin O-glycans with<br />

negative mode nanoLC-mass spectrometry<br />

K.A. Thomsson, M. Backstrom, H. Karlsson, and G.C. Hansson<br />

(University of Gothenburg)<br />

10.30 - 10.50 “Horses for Courses: Bringing glycan analysis to biologists”<br />

N. Packer, P. Jensen, A. Lee, N, Deshpande, M, Nakano, and D,<br />

Kolarich. (Macquarie University)<br />

10.50 - 11.10 Aberrant O-glycosylation of IgA1 and the Pathogenesis of<br />

IgA Nephropathy<br />

M. Renfrow<br />

11.10 - 11.30 “Malectin - a candidate player in the folding/quality control of<br />

N-glycoproteins and disorders underlying human diseases”<br />

Ten Feizi (Imperial College)<br />

11.30 - 11.50 Biomarker for stem cells<br />

M. Pierce (University of Georgia)<br />

General Discussion<br />

Catherine Costello (Boston University)<br />

HUPO Cardiovascular Proteomics Initiative<br />

room: B<br />

09.00 - 12.00<br />

Chairs: Peipei Ping (Los Angeles, USA), Mario Hugo Genero (Buenos Aires, Argentina)<br />

and Thomas Vondriska (Los Angeles, USA)<br />

09.00 Keynote Lecture<br />

Susan Old, NHLBI, USA<br />

09.45 Featured Talk<br />

MingMing Ning, Boston, USA<br />

32 33


10.05 Featured Talk<br />

Fernando Vivanco, Madrid, Spain<br />

10.25 Featured Talk<br />

Arjen Scholten, Utrecht, The Netherlands<br />

10.50 Featured Talk<br />

Ruth Lovering, London, UK<br />

11.30 Round Table Discussion<br />

“HUPO CVI: Components of the Human Proteome Project”.<br />

Frank Vitzthum, Manuel Mayr, Susan Old, Jennifer Van Eyk, Peipei Ping.<br />

HUPO Proteomics Standards Initiative (PSI)<br />

room: CD<br />

09.30 - 12.00<br />

Session chair: Pierre-Alain Binz, Swiss Institute of Bioinformatics, Geneva, Switzerland<br />

The HUPO Proteomics Standards Initiative (PSI) defines community standards for data<br />

representation in proteomics to facilitate data comparison, exchange and verification.<br />

We will present recent progress across PSI work groups, both in the development of<br />

standards, and in the collaboration with journal editors on implementation of standards<br />

as part of the scientific publishing process.<br />

1. Design and implementations of the new PSI’s mass spectrometer<br />

output file standard format: mzML 1.0<br />

Jim Shofstahl, Thermo Electron, San Jose, USA<br />

2. Recent progress on analysisXML, the mass spectrometry analysis format<br />

Martin Eisenacher, “Medizinisches Proteom-Center”,<br />

Ruhr-Universität Bochum, Germany<br />

3. PEFF, a common sequence database format in proteomics<br />

Pierre-Alain Binz, Swiss Institute of Bioinformatics, Geneva, Switzerland<br />

4. Molecular Interaction Standards – from file format to confidence scoring<br />

Sandra Orchard, European Bioinformatics Institute, Cambridge, UK<br />

Human Plasma Proteome Initiative Workshop<br />

09.30 - 12.00<br />

Chairs: Gil Omenn, Ruedi Aebersold and Young-Ki Paik<br />

room EF<br />

1. Technology Platforms<br />

led by Ruedi Aebersold<br />

2. Informatics Platforms and Repositories<br />

led by Eric Deutsch and Lennart Martens<br />

3. Engagement of research groups for submission of major datasets<br />

led by Gil Omenn & Young-Ki Paik<br />

4. Integration across HUPO Initiatives, featuring chairs of other HUPO<br />

initiatives<br />

Monday 18 <strong>August</strong> 2008<br />

location <br />

Room M Room B Room CD Room EF<br />

Room<br />

N-N1-O1-O<br />

Room Forum Room A Room L<br />

Room<br />

Auditorium<br />

Forum Ground<br />

Floor<br />

time <br />

Speaker Ready<br />

Room<br />

Registration &<br />

Information<br />

whole day<br />

Corporate Workshop<br />

Promega<br />

Corporate Workshop<br />

Qiagen<br />

07.00 - 07.50<br />

08.00 - 08.45 Tony Pawson<br />

08.45 - 09.30 Hans Clevers<br />

09.30 - 11.00 Break & Posters in Exhibition Hall 10<br />

S5<br />

Standards for<br />

Clinical Proteomics<br />

S4<br />

Mass Spectrometric<br />

Innovations<br />

S3<br />

Innovation in Peptide &<br />

Protein Separation<br />

Technologies<br />

S2<br />

Molecular Mass<br />

Imaging<br />

S1<br />

Reagents for<br />

proteomics<br />

11.00 - 12.30<br />

Corporate Workshop<br />

Bruker Daltonics<br />

Corporate Workshop<br />

Applied Biosystems<br />

Corporate Workshop<br />

Agilent Technologies<br />

12.30 - 14.00 Lunch, Poster Session & Exhibition in Exhibition Hall 10<br />

S10<br />

Cardiovascular<br />

Proteome Biology<br />

S9<br />

Yeast proteomics;<br />

sparks for new biology<br />

S8<br />

C. elegans and<br />

Drosophila<br />

S7<br />

Plant proteomics<br />

S6<br />

Organelle and biological<br />

membranes Proteomics<br />

14.00 - 15.30<br />

15.30 - 16.00 Break & Posters in Exhibition Hall 10<br />

16.00 - 16.30 Opening Ceremony<br />

16.30 - 17.15 Mathias Uhlén<br />

17.15 - 18.00 Ruedi Aebersold<br />

18.00 - <strong>19</strong>.00 Welcome Reception<br />

Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />

= Initiative = Other meeting<br />

34 35


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Interested in protein arrays? Visit scientific<br />

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©2008 Promega Corporation, 16759-AD-GN<br />

The Night Watch, 1642<br />

Rembrandt van Rijn 1606-1669<br />

Rijksmuseum, Amsterdam<br />

The title of the Night Watch seems to refer to the content of this famous painting, but was introduced<br />

in the 18th century, based on a misapprehension due to dulling of the painting’s surface. However, it<br />

is a day lit scene.<br />

The original title of the Night Watch was: The Company of Frans Banning Cocq and Willem van<br />

Ruytenburch. Rembrandt depicted a division of the civic guard, called Arquebusiers after the arquebus,<br />

a sixteenth-century long-barrelled gun. He displayed the traditional emblem of the Arquebusiers in a<br />

natural way. The chicken claws on the belt of the girl in the yellow dress represent the ‘Clauweniers’-<br />

Arquebusiers. The long-barreled gun, the arquebus, is clearly visible against her yellow dress. The man<br />

in front of her is wearing a helmet with an oak leaf - a traditional motif of the Arquebusiers.<br />

Interestingly, only those who paid were included in the group portrait. Except for the drummer, who<br />

was hired and therefore allowed to be in the painting for free. It is said that Rembrandt cleverly<br />

included himself in the background of this painting. His eye, nose, part of his forehead, and his painter’s<br />

beret are visible above the Captain’s head.<br />

36 37


Plenary Speakers Monday<br />

Tony Pawson<br />

Hans Clevers<br />

BIOGRAPHY<br />

Tony Pawson was an undergraduate at the University of Cambridge (<strong>19</strong>70-<strong>19</strong>73),<br />

obtained his Ph.D. at the Imperial Cancer Research Fund, London, and did postdoctoral<br />

work at the University of California at Berkeley (<strong>19</strong>76-<strong>19</strong>80). He moved to the University<br />

of British Columbia as an Assistant Professor, and then to the Samuel Lunenfeld<br />

Research Institute of Mt. Sinai Hospital, University of Toronto in <strong>19</strong>85, where he<br />

was Director of Research (2000-2005). Over the last 25 years he has explored the<br />

mechanisms through which modular protein-proteins interactions control intracellular<br />

signaling networks, building on the identification of the SH2 domain as the prototypic<br />

interaction module.<br />

abstract<br />

Proteomic analysis of reciprocal cell signalling<br />

T. Pawson, C. Jorgensen, A. Sherman, Samuel Lunenfeld Reseach Institute<br />

Mt. Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada<br />

Signaling proteins are typically constructed in a modular fashion, from domains<br />

that mediate either molecular interactions or catalytic <strong>event</strong>s, and corresponding<br />

interaction or substrate motifs. The joining of domains in new combinations can provide<br />

novel functions in evolution, both by creating new intermolecular connections, and by<br />

forming new and varied modes of allosteric regulation. This notion will be discussed in<br />

the context of cytoplasmic tyrosine kinases such as Fes and Abl.<br />

Intercellular signaling is typically investigated experimentally in the context of a signal,<br />

such as a growth factor, impinging on a receptor on a target cell. In vivo, however,<br />

neighboring cells often signal back-and-forth in a reciprocal fashion. We have used a<br />

combination of proteomic and functional screens to investigate the means by which<br />

cells exchange and respond to such two-way signals, using phosphotyrosine-based<br />

intracellular networks.<br />

BIOGRAPHY<br />

Hans Clevers obtained his MD degree in <strong>19</strong>84 and his PhD degree in <strong>19</strong>85 from the<br />

University of Utrecht, the Netherlands. His postdoctoral work (<strong>19</strong>86-<strong>19</strong>89) was done<br />

with Cox Terhorst at the Dana-Farber Cancer Institute of the Harvard University,<br />

Boston, USA.<br />

From <strong>19</strong>91-2002, Hans Clevers was Professor in Immunology at the University of<br />

Utrecht and, since 2002, Professor in Molecular Genetics. Since 2002, he is Director<br />

of the Netherlands Institute for Developmental Biology, Utrecht.<br />

Hans Clevers has been a member of the Royal Dutch Academy of Sciences since 2000<br />

and is the recipient of several awards, including the Dutch Spinoza Award in 2001, the<br />

Swiss Louis Jeantet Prize in 2004, the Memorial Sloan-Kettering Katharine Berkan<br />

Judd Award in 2005 and the Israeli Rabbi Shai Shacknai Memorial Prize in 2006.<br />

abstract<br />

Identification of stem cells in small intestine and colon by a single marker gene lgr5<br />

H. Clevers, Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands<br />

The intestinal epithelium is the most rapidly self-renewing tissue in adult mammals.<br />

Current models state that 4-6 crypt stem cells reside at the +4 position immediately<br />

above the Paneth cells in the small intestine; colon stem cells remain undefined. Lgr5/<br />

Gpr49 was selected from a panel of intestinal Wnt target genes for its restricted<br />

crypt expression. Two knock-in alleles revealed exclusive expression of Lgr5 in cycling,<br />

columnar cells at the crypt base. In addition, Lgr5 was expressed in rare cells in<br />

several other tissues. Using an inducible Cre knock-in allele and the Rosa26-LacZ<br />

reporter strain, lineage tracing experiments were performed in adult mice. The<br />

Lgr5+ve crypt base columnar cell (CBC) generated all epithelial lineages over a 60-day<br />

period, implying that it represents the stem cell of the small intestine and colon. The<br />

expression pattern of Lgr5 suggests that it marks stem cells in multiple adult tissues<br />

and cancers.<br />

38 39


Mathias Uhlén<br />

Ruedi Aebersold<br />

BIOGRAPHY<br />

Mathias Uhlén is Professor of Microbiology at the Royal Institute of Technology (KTH),<br />

Stockholm, Sweden. Prof. Uhlén is member of the Royal Swedish Academy of Engineering<br />

Science (IVA), the Royal Swedish Academy of Science (KVA) and the European Molecular<br />

Biology Organization (EMBO). He is Vice-President of the European Proteomics<br />

Association (EuPA) and member of the Human Proteome Organization
(HUPO) council.<br />

He was Vice-President of the Royal Institute of Technology (KTH), responsible for<br />

external relations, from <strong>19</strong>99 to 2001 and he was the chairman of the Swedish<br />

Biochemical and Molecular Biology Society (SFMB) from <strong>19</strong>94 to <strong>19</strong>99. Prof. Uhlén has<br />

more than 300 publications in bioscience with the focus on the development and use<br />

of affinity reagents in biotechnology and biomedicine.<br />

abstract<br />

A Human Protein Atlas<br />

Mathias Uhlén<br />

Royal Institute of Technology, School of Biotechnology, AlbaNova University Center,<br />

Stockholm, Sweden, +46 8 5537 8325, E-mail: mathias@biotech.kth.se<br />

The new version 4.0 of the Human Protein Atlas (www.proteinatlas.org) has been<br />

generated with more than 6,000 validated antibodies corresponding to 5,000 human<br />

genes. The portal contains more than 4 million high-resolution images generated<br />

by immunohistochemistry and confocal microscopy. Each image has been manually<br />

annotated and curated by a certified pathologist to provide a knowledge base for<br />

functional studies and to allow searches and queries about protein profiles in normal<br />

and disease tissue. A new structure has been implemented with the inclusion of all<br />

predicted genes (approximately 20,500) with a visualization of the encoded protein<br />

characteristics for all genes. A new search tool is also launched in which advance<br />

queries can be performed, including searches for chromosome location, protein class<br />

and/or tissue specificity. Our results suggest that it should be possible to extend<br />

the protein atlas to a majority of all human proteins thus providing a valuable tool for<br />

medical and biological research.<br />

Berglund et al (2008) “The epitope space of the human proteome” Protein Science 17, 606-613.<br />

Björling et al (2008) “A web-based tool for in silico biomarker discovery based on tissue-specific protein profiles in normal and<br />

cancer tissues” Mol Cell Proteomics 7(5): 825-44.<br />

Barbe et al (2008) “Toward a confocal subcellular atlas of the human proteome” Mol Cell Proteomics. 7(3):499-508<br />

BIOGRAPHY<br />

Ruedi Aebersold is the Professor for Molecular Systems Biology at ETH Zurich and<br />

the University of Zurich, Switzerland and co-founder of the Institute for Systems<br />

Biology in Seattle, WA. Research in his group is focused on the development and the<br />

application of proteomics technologies towards a better understanding of biological<br />

systems and processes.<br />

abstract<br />

Proteome biology<br />

Ruedi Aebersold - ETH Zurich, Switzerland, Institute of Molecular Systems Biology, USA<br />

aebersold@imsb.biol.ethz.ch<br />

Biological processes can be viewed as networks of interacting components, whereby<br />

the structure and dynamics of the network determines the properties of the process.<br />

Different types of such networks concurrently exist in the cell and many consist of or<br />

contain proteins. Examples include protein:protein interaction networks, networks of<br />

enzymes and their substrates, networks of microRNA’s and their targets, protein:DNA<br />

interaction networks etc. The study of such networks requires proteomic technologies<br />

that are capable of detecting and quantifying any protein of a given network, to<br />

determine the network connections and their dynamic change and to relate the results<br />

of measurements made on cell or tissue extracts back to the living cell.<br />

In this presentation we will discuss technical and conceptual advances in proteomics<br />

that support proteome biology. These include the ability to detect reliably and quantify<br />

essentially any protein in a yeast cell by targeted, SRM based high sensitivity mass<br />

spectrometry, the ability to determine the true composition of protein complexes<br />

that exist in the cell and to visualize them in near life cells, and the ability to measure<br />

phosphorylation modulated regulatory networks. The technical advances will be<br />

illustrated with suitable examples.<br />

40 41


Full Program details<br />

Monday 18 <strong>August</strong><br />

8.00-8.45 Plenary 1 Proteomic analysis of reciprocal cell signaling room: Auditorium<br />

Tony Pawson (Samuel Lunenfeld Research Institute, CANADA),<br />

claus Jorgensen, Andrew Sherman<br />

Chairperson: Anne-Claude Gavin<br />

8.45-9.30 Plenary 2 IDENTIFICATION OF STEM CELLS IN SMALL INTESTINE AND Room: Auditorium<br />

COLON BY A SINGLE MARKER GENE LGR5<br />

Hans Clevers (Hubrecht Institute, THE NETHERLANDS)<br />

Chairperson: Albert Heck<br />

S3 Innovation In Peptide & Protein Separation Technologies Room: A 11.00-12.30<br />

Chairpersons: Rong Zeng & Martijn Pinkse<br />

Separation and Identification of Phosphopeptides Based on Multiple Dimensional Liquid 11.00-11.30<br />

Chromatography Mass Spectrometry<br />

Jie Dai, Qing-Run Li, Chia-Hui Shieh, Rong Zeng (Shanghai Institutes for Biological Sciences, CHINA)<br />

Coupling Immobilized Enzyme Microreactors with MICRORPLC-MS/MS for Protein Analysis 11.30-11.50<br />

Junfeng Ma (Dalian Institute of Chemical Physics, Chinese Academy of Sciences, CHINA), Lihua Zhang,<br />

Zhen Liang, Yukui Zhang<br />

3D-GEL Electrophoresis, A New Approach to Comparative Protein Analysis 11.50-12.10<br />

Robert Ventzki (European Molecular Biology Laboratory, GERMANY), Sjouke Hoving, Jan van Oostrum,<br />

Josef Stegemann<br />

High Sensitivity RP/RP/LC/MS Platform for Assessing Protein Complex Dynamics 12.10-12.30<br />

Scott Ficarro (Dana-Farber Cancer Institute, UNITED STATES), Feng Zhou, Guillaume Adelmant, Job Cardoza,<br />

Manor Askenazi, Jarrod Marto<br />

11.00-12.30 S1 Reagents For Proteomics room: Auditorium<br />

Chairpersons: Andreas Plückthun & Hermen Overkleeft<br />

11.00-11.30 Novel binding proteins by design and evolution<br />

Andreas Plückthun (University of Zurich, SWITZERLAND)<br />

11.30-11.50 Antibody QA Pipeline For Proteomics Researchers: Nci’s Antibody Characterization Program<br />

Henry Rodriguez, Mehdi Mesri, Gordon Whiteley, Chris Kinsinger (National Cancer Institute/National Institutes<br />

of Health, UNITED STATES)<br />

11.50-12.10 Fluorescent Isotope Coded Affinity Tag (FCAT) for Quantitative Proteomics<br />

Andras Guttman (Horvath Laboratory of Bioseparation Sciences, AUSTRIA), Zuly Rivera<br />

12.10-12.30 Design of Recombinant SCFV Antibodies for High-Throughput Affinity-Based Proteomics<br />

Malin Kristensson (Lund University, SWEDEN), Jacob Vallkil, Katarina Loof, Carl AK Borrebaeck, Christer Wingren<br />

S4 Mass Spectrometric Innovations Room: L 11.00-12.30<br />

Chairperson: Carol Robinson<br />

Subunit Architecture of Multiprotein Complexes Isolated Directly from Cells - Insights from 11.00-11.30<br />

Mass Spectrometry of Intact Complexes<br />

Caron Robinson (University of Cambridge, UNITED KINGDOM), H Hernández, AM Sandercock, M Zhou,<br />

B Ruotolo, T Nelson, P Barrera<br />

High Resolution Mass Spectrometry to Study Functional Protein Complexes 11.30-11.50<br />

Esther van Duijn (Utrecht University, THE NETHERLANDS), Charlotte Uetrecht, Arjen Barendregt,<br />

Kees Versluis, Albert Heck<br />

Microfluidic Platform for ESI (DESI) and MALDI (LDI) Shotgun Proteomic Analysis 11.50-12.10<br />

Daniel Knapp (Medical University of South Carolina, UNITED STATES), Jian Liu, Ranu Nayak, Daniel Higbee<br />

Targeted Peptide Identification Based on Selected Reaction Monitoring 12.10-12.30<br />

Bruno Domon (ETH Zurich, SWITZERLAND), Paola Picotti, Nathalie Selevsek, Ruedi Aebersold<br />

11.00-12.30 S2 Molecular Mass Imaging room: Forum<br />

Chairperson: Richard Caprioli<br />

11.00-11.30 Molecular Imaging and Profiling of Tissues with Mass Spectrometry:<br />

applications in Biological and Clinical Research<br />

Richard Caprioli (Vanderbilt University, UNITED STATES)<br />

11.30-11.50 Direct Mass Spectromectric Imaging of Human Brain Tissue<br />

Ron M.A. Heeren (FOM Institute for Atomic and Molecular Physics, THE NETHERLANDS), Kükrer Kaletas,<br />

Ingrid van der Wiel, Jonathan Stauber, Lennart Dekker, C. Güzel, Theo M. Luider<br />

11.50-12.10 Protein Unlocking of Formalin Stored (FFPE) Tissues: Application to MALDI-TOF-IMAGING-MS<br />

Maurizio Ronci (European Centre for Brain Research (CERC), Fondazione - Santa Lucia, ITALY), Elena Bonanno,<br />

Alfredo Colantoni, Luisa Pieroni, Carmine di Ilio, Luigi Giusto Spagnoli, Giorgio Federici, Andrea Urbani<br />

12.10-12.30 On Tissue Fractionation: Unmasking Difficult Proteins for MALDI profiling<br />

Isabelle Fournier (University of Lille 1, Laboratoire de Neuroimmunologie des Annelides, FRANCE),<br />

David Bonnel, Julien Franck, Maxence Wisztorski, Mohamed El Ayed, Michel Salzet<br />

S5 Standards For Clinical Proteomics room: N-N1-O1-O 11.00-12.30<br />

Chairpersons: Henry Rodriguez & Christian Stephan<br />

Introduction by Henry Rodriguez 11.00-11.10<br />

Performance and Optimization of LC-MS/MS Platforms for Proteomic Analyses: An Interlaboratory Study 11.10-11.30<br />

Daniel Liebler (Vanderbilt University School of Medicine, UNITED STATES), Amanda Paulovich<br />

Verification of Candidate Protein Biomarkers: Reproducibility of MRM-BASED Assays 11.30-11.50<br />

Steven Hall (University of California San Francisco, UNITED STATES), Terri Addona, Steven Skates, David Bunk<br />

Measures of Variability in Shotgun Proteomics Experiments 11.50-12.10<br />

Steve Stein (National Institute of Standards and Technology, UNITED STATES), Lisa Kilpatrick,<br />

Yuri Mirokhin, Paul Rudnick, Dmitrii Tchekhovskoi, Eric Yan, Xiouyu Yang<br />

Absolute Silac for Accurate Quantitation of Proteins in Complex Mixtures Down to the Attomole Level 12.10-12.30<br />

Stefan Hanke (Max-Planck-Institute for Biochemistry, Dept of Proteomics and Signal Transduction, GERMANY),<br />

Hüseyin Besir, Dieter Oesterhelt, Matthias Mann<br />

42 43


Full Program details<br />

Monday 18 <strong>August</strong><br />

14.00-15.30 S6 Organelle And Biological Membranes Proteomics room: Auditorium<br />

Chairpersons: John Bergeron & Bert Poolman<br />

14.00-14.30 The Protein Microscope and Organellar Proteomics<br />

John Bergeron (McGill University, CANADA), Catherine Au, Michael Jain, Jeff Smirle, Alexander Bell, Tommy Nilsson<br />

14.30-14.50 Membrane Proteome of the Yeast Nuclear Envelope<br />

L.M. Veenhoff (University of Groningen, THE NETHERLANDS), J.A. Demmers, M.C. King, A.C. Meinema, B. Poolman<br />

14.50-15.10 Organelle Mapping of the Human Proteome - Towards a Subcellular Atlas<br />

Emma Lundberg (School of biotechnology, Royal institute of Technology (KTH), SWEDEN), Laurent Barbe,<br />

Per Oksvold, Anna Stenius, Erik Björling, Anna Asplund, Fredrik Pontén, Hjalmar Brismar, Mathias Uhlén,<br />

Helene Andersson-Svahn<br />

15.10-15.30 Proteome of Hydrogenosomes and Mitosomes<br />

Petr Jedelsky (Charles University in Prague, Faculty of Science, CZECH REPUBLIC), Miroslava Sedinova,<br />

Petr Rada, Neritza Campo Beltran, Jan Tachezy<br />

S9 Yeast Proteomics; Sparks For New Biology room: L 14.00-15.30<br />

Chairpersons: Mike Tyers & Liesbeth Veenhoff<br />

Systematic Interrogation of the Budding Yeast Kinome 14.00-14.30<br />

Ashton Breitkreutz, Brett Larsen, Hyungwon Choi, Zhen-Yuan Lin, Jeff Sharom, Lorrie Boucher, Danielle Dewar,<br />

Rune Linding, Tony Pawson, Anne-Claude Gingras, Alexey Nesvizhskii, Mike Tyers (Samuel Lunenfeld Research Institute,<br />

Mount Sinai Hospital, CANADA, Wellcome Trust Centre for Cell Biology, School of Biological Sciences,<br />

University of Edinburgh, UNITED KINGDOM)<br />

An in Vivo Map of the Yeast Protein Interactome 14.30-14.50<br />

Kirill Tarassov, Vincent Messier, Christian R. Landry, Stevo Radinovic, Mercedes M. Serna Molina, Igor Shames,<br />

Yelena Malitskaya, Jackie Vogel, Howard Bussey, Stephen W. Michnick (Département de Biochimie,<br />

Université de Montréal, Centre Robert-Cedergren, Bio-Informatique et Génomique, CANADA)<br />

The Yeast Nuclear Proteome: Composition and Complexes 14.50-15.10<br />

Sharon Gauci (Utrecht University, THE NETHERLANDS), Liesbeth M. Veenhoff, Albert J. R. Heck, Jeroen Krijgsveld<br />

Analysis of the S. Cerevisiae Metabolic Network by Targeted Proteomics 15.10-15.30<br />

Paola Picotti (Institute of Molecular Systems Biology, ETH Zuerich, SWITZERLAND), Anne Kuemmel, Roeland Costenoble,<br />

Henry Lam, David Campbell, Matthias Heinemann, Eric Deutsch, Uwe Sauer, Bruno Domon, Ruedi Aebersold<br />

14.00-15.30 S7 Plant Proteomics room: Forum<br />

chairperson: Steven Briggs<br />

14.00-14.30 Quantitative Changes in the Arabidopsis Proteome Caused by Pathogen Signals<br />

SP Briggs (University of California San Diego, UNITED STATES), Z Shen, C van Schie, A Mason, S Payne,<br />

N Castellana, V Bafna, EH Chung, J Dangl<br />

14.30-14.50 Digging Into the Plant Proteome<br />

Sergey Sikora (GenWay Biotech, Inc, UNITED STATES), Lei Huang, Xiangming Fang<br />

14.50-15.10 Proteomic Analysis of the Endophytic Interaction of Gluconacetobacter Diazotrophicus with Sugarcane<br />

Leticia Lery (Unidade Multidisciplinar de Genômica, Universidade Federal do Rio de Janeiro, BRAZIL),<br />

Eduardo Nogueira, Wanda von Kruger, Adriana Hemerly, Paulo Bisch<br />

15.10-15.30 Profiling of Receptor-like Kinases Membrane Protein Family in Arabidopsis Thaliana<br />

Fabrizia Fusetti (Department of Biochemistry, University of Groningen, THE NETHERLANDS),<br />

Hamid Najafi Zarrini, Wim Huibers, Theo Elzenga, Frank Lanfermijer, Bert poolman<br />

S10 Cardiovascular Proteome Biology roomN-N1-O1-O 14.00-15.30<br />

Chairpersons: Peipei Ping & Arjen Scholten<br />

Session sponsored by<br />

The Dynamics of Mitochondrial Proteome in the Murine Heart 14.00-14.30<br />

Peipei Ping (UCLA, UNITED STATES)<br />

Development of a Novel Immunoassay for Characterizing Circulating Form of Cardiac Troponin 14.30-14.50<br />

Jennifer Van Eyk (Bayview proteomics center, Johns Hopkins University, UNITED STATES), Yixin lin, Qin Fu<br />

Nitric Oxide Induced Changes of the Heart Phosphoproteome 14.50-15.10<br />

Annamária Simon (Institute of Cardiovascular Physiology, Heinrich-Heine-University of Düsseldorf, GERMANY),<br />

Michael Reinartz, Ulrich Flögel, Jürgen Schrader<br />

Profiling Protein Expression in Human Dilated Cardiomyopathy; Global and Targeted Analyses 15.10-15.30<br />

Arjen Scholten (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht University, THE NETHERLANDS),<br />

Thin-Thin Aye, Marcel van der Heyden, Marc Vos, Toon van Veen, Albert Heck<br />

14.00-15.30 S8 C. Elegans And Drosophila room: A<br />

Chairpersons: Michael Hengartner & Michael O. Glocker<br />

14.00-14.30 Idenfication and Characterization of the C. Elegans Proteome<br />

Michael Hengartner (University of Zurich, SWITZERLAND)<br />

14.30-14.50 System-Wide Analysis of Phosphatase Knock-Down in Drosophila by Quantitative Proteomics<br />

Maximiliane Hilger (Department of Proteomics and Signal Transduction, Max-Planck Institute for<br />

Biochemistry, GERMANY), Tiziana Bonaldi, Florian Gnad, Chanchal Kumar, Jürgen Cox, Matthias Mann<br />

14.50-15.10 Genome-Wide Characterization of Proteins Involved in Cell-Cycle Regulation<br />

Mikael Björklund (University of Helsinki and National Public Health Institute, FINLAND), Mikko Turunen,<br />

Martin Bonke, Maria Sokolova, Minna Taipale, Jussi Taipale<br />

Plenary 3 A HUMAN PROTEIN atlas room: Auditorium 16.30-17.15<br />

Mathias Uhlén (AlbaNova University Center, SWEDEN)<br />

Chairperson: Peipei Ping<br />

Plenary 4 Proteome Biology room: Auditorium 17.15-18.00<br />

Ruedi Aebersold (ETH Zürich, SWITZERLAND<br />

institute of Molecular Systems Biology, United States)<br />

Chairperson: Denis Hochstrasser<br />

1510-1530 QUANTITATIVE PROTEOME ATLAS OF THE ADULT HONEY BEE CASTES<br />

Queenie Chan (University of British Columbia, CANADA), Yuan Fang, Man Yi Chan, Michelle Logan,<br />

Heather Higo, Leonard Foster<br />

44 45


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GE11-08<br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong> 2008<br />

location <br />

Room M Room B Room CD Room EF Room P<br />

Room<br />

N-N1-O1-O<br />

Room Forum Room A Room L<br />

Room<br />

Auditorium<br />

Forum Ground<br />

Floor<br />

time <br />

Speaker Ready<br />

Room<br />

Registration &<br />

Information<br />

whole day<br />

Corporate Workshop<br />

GE Healthcare<br />

Corporate Workshop<br />

Rosetta Bio<strong>software</strong><br />

07.00 - 07.50<br />

08.00 - 08.45 Peter Andrews<br />

08.45 - 09.30 Matthias Mann<br />

09.30 - 11.00 Break & Posters in Exhibition Hall 10<br />

S15<br />

Glycoproteomics<br />

S14<br />

Alternative splicing &<br />

protein processing<br />

S13<br />

EuPA Young<br />

Investigator Session<br />

S12<br />

Computational<br />

approaches to mine<br />

proteomic data<br />

S11<br />

Phosphoproteomics<br />

11.00 - 12.30<br />

Corporate Workshop<br />

Promega<br />

Corporate Workshop<br />

Bruker Daltonics<br />

Corporate Workshop<br />

Dionex<br />

Corporate Workshop<br />

Thermo Scientific<br />

12.30 - 14.00 Lunch, Poster Session & Exhibition in Exhibition Hall 10<br />

S20<br />

Proteomics of the<br />

nervous systems<br />

S<strong>19</strong><br />

Proteomics and<br />

epigenetics<br />

S18<br />

Proteomics of<br />

Macro-molecular<br />

Complexes<br />

S17<br />

Kinase-protein<br />

substrate networks<br />

S16<br />

Chemical<br />

Proteomics<br />

14.00 - 15.30<br />

15.30 - 16.00 Break & Posters in Exhibition Hall 10<br />

16.00 - 16.45 Anne-Claude Gavin<br />

16.45 - 17.30 Erin O’Shea<br />

HUPO General<br />

Assembly<br />

17.30 - <strong>19</strong>.30<br />

Translating biomarkers<br />

from the bench to<br />

the bedside<br />

(Salvatore Sechi)<br />

20.00 - 22.30<br />

Workshop on<br />

Proteomics Validation<br />

Sudhir Srivastava &<br />

William Hancock<br />

Publishing in<br />

Proteomics:<br />

A dialogue of investigators<br />

and journals<br />

(Peipei Ping)<br />

20.00 - 22.00<br />

Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />

= Initiative = Other meeting<br />

46 47


Plenary Speakers <strong>Tuesday</strong><br />

Peter Andrews<br />

Matthias Mann<br />

BIOGRAPHY<br />

Peter Andrews is Professor of Biomedical Science at Sheffield University, where he<br />

also co-directs the Centre for Stem Cell Biology. His research focuses on the biology<br />

of human ES cells. He co-ordinates the International Stem Cell Initiative, focused upon<br />

characterising human ES cells.<br />

abstract<br />

Population Dynamics, Self Renewal and Culture Adaptation of Human ES cells<br />

Peter W Andrews, Centre for Stem Cell Biology and Department of Biomedical Science,<br />

The University of Sheffield, Sheffield, S10 2TN, UK<br />

Teratocarcinomas, a subset of germ cell tumours, have long provided a paradigm for<br />

the stem cell concept of cancer, and the role of their stem cells, embryonal carcinoma<br />

(EC) cells, in their development is well known. Embryonic stem (ES) cells isolated<br />

from early embryos are the apparently ‘normal’ counterpart of tumour-derived EC<br />

cells. However, ES cells may acquire non-random karyotypic changes on prolonged<br />

culture. In human ES cells, these changes typically involve gain of genetic material<br />

from chromosomes 17, 12 and X, and resemble similar changes observed in EC cells<br />

from testicular teratocarcinomas, one of the most common cancers of young men.<br />

As a working hypothesis, we can imagine that the over expression of genes located<br />

on these chromosomes increases the probability of self renewal of pluripotent stem<br />

cells, at the expense of commitment to differentiation or apoptosis. A corollary is the<br />

proposition that these genes play a key role in regulating stem cell behaviour and their<br />

disruption may affect tumour progression, particularly in germ cell tumours, in which<br />

enhanced self renewal capacity might equate to a more aggressive tumour phenotype.<br />

A key problem is to identify the genes that contribute this type of selective overgrowth<br />

of variant stem cells in which they are over expressed. The available data suggest that<br />

only a relatively small number of genes is involved, maybe as few as five, but that these<br />

may act independently on different aspects of the control of stem cell behaviour.<br />

Identification of these genes would provide the basis for developing better techniques<br />

for ES cell culture to avoid selection pressure for over-expressing variants. It may<br />

also provide insights into the development and progression of teratocarcinomas, and<br />

provide a model for understanding other stem cell based cancers.<br />

BIOGRAPHY<br />

Matthias Mann received his doctorate degree from Yale University with John Fenn,<br />

where he contributed to the development of electrospray mass spectrometry. Prof.<br />

Mann is now a director at the Max-Planck Institute of Biochemistry in Martinsried,<br />

Germany. His group continues to develop proteomics technology and to address cell<br />

signaling problems using proteomics.<br />

abstract<br />

Spatio-temporal proteomics<br />

M. Mann - email: mmann@biochem.mpg.de, J.V. Olsen, C. Robles, C. Choudhary, N.C.<br />

Hubner, J. Graumann, J. Cox, F. Forner, C. Kumar and H. Serve*.<br />

Dept. of Proteomics and Signal Transduction, Max Planck Institute for Biochemistry,<br />

Am Klopferspitz 18, D-82512 Martinsried near Munich, Germany.<br />

*Dept. Internal Medicine, University of Frankfurt, Germany<br />

Mass spectrometry-based proteomics has usually been performed in a qualitative<br />

format although the community is rapidly realizing that biological conclusions can best<br />

be obtained from quantitative data. Quantitation allows measurement of spatial as<br />

well as temporal proteomes. This capability in turn makes proteomics an excellent<br />

complement to powerful imaging methods used in modern cell biology. Proteomics is<br />

unbiased and can be used in a ‘discovery mode’ whereas imaging technologies have<br />

higher sub-cellular resolution and are single cell based. Here I discuss recent technology<br />

developments and applications of quantitative proteomics combined with imaging<br />

technologies.<br />

Signalling can be different in quantity and quality depending on the intracellular compartment.<br />

Here we employed quantitative phosphoproteomics to show that the Flt3<br />

receptor with an internal tandem domain (ITD), which is the most common kinase<br />

mutation in Acute Myeloid Leukaemia, signals differently as a result of different compartmentalization.<br />

Temporal proteomics has first been demonstrated in the context of tyrosine signalling.<br />

Here we show that the temporal evolution of both the phosphoproteome and the<br />

proteome can be followed in SILAC based proteomics.<br />

Finally, we introduce PROSPECTS (Proteomics in Space and Time), a large European<br />

proteomics network, whose purpose is the elucidation of spatio-temporal proteomics<br />

by a combination of different technologies.<br />

48 49


Anne-Claude Gavin<br />

Erin O’Shea<br />

BIOGRAPHY<br />

Anne-Claude Gavin is Group Leader in the Structural and Computational Biology Unit<br />

at the European Molecular Biology Laboratory, Heidelberg. Before joining the EMBL<br />

she was a scientific director at Cellzome AG. In 2002 she received the Genome<br />

Technology All-Stars Award in proteomics. Her group has been proponent and pioneer<br />

of more general strategies aiming at understanding complex biological systems. With<br />

more than 1.500 citations, the system-wide characterization of protein complexes<br />

in a model eukaryote, Saccharomyces cerevisiae, by affinity purification and mass<br />

spectrometry is generally considered as a breakthrough. Her main research interest<br />

includes the study of biomolecular interaction, the understanding of the principles that<br />

govern the assembly and dynamics of protein networks.<br />

abstract<br />

The social network of a cell: dynamic protein interactions<br />

Anne-Claude Gavin, EMBL Heidelberg, Germany, gavin@embl.de<br />

Recent developments in the -omics field have provided comprehensive repertoires<br />

of RNAs, proteins, metabolites that constitute the cell building blocks. The next<br />

challenge resides in the understanding of how the “pieces” of this puzzle assemble,<br />

combine and contribute to the assembly of a coherent entity; a cell. Biology relies on<br />

the concerted action of a number interacting proteins and metabolites operationally<br />

organized in cellular pathways or networks. However, current appreciation of the “wiring<br />

diagram” or “molecular maps” of these pathways is scanty. We used tandem-affinity<br />

purification and mass spectrometry (TAP/MS) to perform a system-wide analysis for<br />

protein complexes in a model organism, budding yeast. The study provides one of the<br />

largest collections of physically-determined eukaryotic cellular machines. Beyond the<br />

repertoire, the analysis captures the modular nature of proteomes. In an attempt<br />

to move from static interaction networks to more dynamic maps, we developed an<br />

innovative scoring system that captures some biochemical properties of proteinprotein<br />

interaction: the likelihood to be in direct physical contact and, weakly, the<br />

dissociation constants. We believe that in the future, experimental and computational<br />

refinements may turn such scoring approaches into suitable parameters for rational<br />

modeling of (entire) systems.<br />

BIOGRAPHY<br />

Dr. O’Shea is an Investigator of the Howard Hughes Medical Institute, Director of<br />

the Harvard Faculty of Arts Sciences Center for Systems Biology and Professor of<br />

Molecular and Cellular Biology and Chemistry and Chemical Biology at Harvard University.<br />

She received her undergraduate degree from Smith College and her Ph.D. degree from<br />

the Massachusetts Institute of Technology. Dr. O’Shea’s honors include the National<br />

Academy of Sciences Award in Molecular Biology, a Packard Foundation Fellowship,<br />

and a Presidential Faculty Fellow Award. She is a member of the American Academy of<br />

Arts and Sciences and the National Academy of Sciences.<br />

abstract<br />

Signaling Nutrient Limitation<br />

E. O’Shea, Harvard University<br />

Howard Hughes, Medical Institute, Harvard Faculty of Arts and Sciences Center for<br />

Systems Biology, Departments of Molecular and Cellular Biology and Chemistry and<br />

Chemical Biology, Harvard University, 7 Divinity Avenue, Cambridge MA USA<br />

In conditions of nutrient limitation, cells maintain homeostasis by altering metabolomic,<br />

proteomic, and genomic profiles. Many nutrient-starvation response systems have<br />

been intensively studied in Saccharomyces cerevisiae; the cellular response to inorganic<br />

phosphate starvation is one of the best characterized. Our recent work has revealed<br />

that myo-d-inositol heptakisphosphate (IP7) is produced in response to phosphate<br />

limitation and regulates the activity of a protein kinase complex that coordinates<br />

downstream cellular responses. We are currently investigating the mechanism of<br />

action of IP7 and studying the metabolic changes that occur when cells are limited for<br />

inorganic phosphate.<br />

50 51


Full Program details<br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />

8.00-8.45 Plenary 5 Population Dynamics, Self Renewal and Culture Room: Auditorium<br />

Adaptation of Human ES cells<br />

Peter Andrews (University of Sheffield, UNITED KINGDOM)<br />

Chairperson: Jeroen Krijgsveld<br />

8.45-9.30 Plenary 6 Spatio-temporal proteomics room: Auditorium<br />

Matthias Mann (Max Plank Institute for Biochemistry, GERMANY),<br />

Jesper Olsen, Charo Robles, Nina Hubner, Johannes Graumann,<br />

Juergen Cox, Francesca Forner, Chanchal Kumar, Hubert Serve<br />

Chairperson: Ruedi Aebersold<br />

S13: EuPA Young Investigator Session room: A 11.00-12.30<br />

Chairperson: Concha Gil<br />

A Novel Approach Enabling Exploratory and Targeted Analysis with a Single LC-injection 11.05-11.22<br />

Leonie F Waanders (Max Planck Institut for Biochemistry, GERMANY), Reinaldo Almeida, Peter Bandilla,<br />

Mark H Allen, Gary A Schultz, Matthias Mann<br />

On-Line Automated In Vivo Zebrafish Phosphoproteomics 11.22-11.39<br />

Simone Lemeer (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht University, Hubrecht Institute,<br />

THE NETHERLANDS), Shabaz Mohammed, Bas van Breukelen, Jeroen den Hertog, Monique Slijper, Albert Heck<br />

DLK1 Functions in Stem Cells Studied by Quantitative Phosphoproteomics by ITRAQ and SIMAC 11.39-11.56<br />

Tine E. Thingholm (University of Southern Denmark, DENMARK), Bassem M. Abdallah, Moustapha Kassem,<br />

Ole N. Jensen<br />

Analysis of the Yeast Protein Kinase - Substrate Networks by Quantitative Phosphoproteomics 11.56-12.13<br />

Bernd Bodenmiller (Institute of Molecular Systems Biology, ETH Zurich, SWITZERLAND), Paul Shannon, Bertran<br />

Gerrits, Claudine Kraft, Mi-Youn Brusniak, Lukas Mueller, Matthias Peter, Ralph Schlapbach, Ruedi Aebersold<br />

Integrated Membrane Protein Analysis Using a Novel Combination of CY-DYE/BIOTIN Labeling 12.13-12.30<br />

Anissa Sidibe (King’s College, University of London, UNITED KINGDOM), Xiaoke Yin, Qingzhong Xiao,<br />

Anna Zampetaki, Qingbo Xu, Manuel Mayr<br />

11.00-12.30 S11 Phosphoproteomics room: Auditorium<br />

Chairpersons: Ole Jensen & Shabaz Mohammed<br />

11.00-11.30 Phosphoproteomics - Quo Vadis? Challenges and Trends in Protein Phosphorylation Analysis<br />

Ole Jensen (University of Southern Denmark, DENMARK)<br />

11.30-11.50 Optimization of Elution Conditions for Phosphopeptides Captured by Aliphatic Hydroxy Acid-Modified<br />

metal Oxide Chromatography (HAMMOC)<br />

Yutaka Kyono (Keio Univ. IAB, JAPAN), Naoyuki Sugiyama, Koshi Imami, Masaru Tomita, Yasushi Ishihama<br />

11.50-12.10 The Use of Phosphoproteomics to Discover Novel AMPK Substrates<br />

Nicholas Morrice (MRC Protein Phosphorylation Unit, UNITED KINGDOM), Franck Vandermoere, Kei Sakamoto<br />

12.10-12.30 Phosphoproteomic Analysis of Host Signaling Events Induced by Salmonella<br />

Lindsay D Rogers (The University of British Columbia, CANADA), Yuan Fang, Erin C Boyle, Leonard J Foster<br />

S14 Alternative Splicing & Protein Processing room: L 11.00-12.30<br />

Chairpersons: Kris Gevaert & Jeroen Demmers<br />

Systematic Protease Degradomics by Targeted Gel-Free Proteomics 11.00-11.30<br />

Kris Gevaert (Ghent University, BELGIUM), Petra Van Damme, Francis Impens, Veerle Vandenbussche,<br />

Kim Plasman, Kenny Helsens, Niklaas Colaert, Joël Vandekerckhove<br />

Multiplex System-Wide Discovery of Protease Substrates and Their Cleavage Sites 11.30-11.50<br />

Anna Prudova (University of British Columbia, CANADA), Ulrich auf dem Keller, Christopher Overall<br />

Alternative Splicing Detection in Large Scale Proteomics 11.50-12.10<br />

Alexandre Podtelejnikov (Proxeon A/S, DENMARK), Christian Ingrell, Morten Bern<br />

Dynamic Regulation of SUMO-2/3 Conjugates by the Ubiquitin-Proteasome System 12.10-12.30<br />

Alfred Vertegaal (Department of Molecular Cell Biology, Leiden University Medical Center, THE NETHERLANDS),<br />

Joost Schimmel, Katja Larsen, Ivan Matic, Martijn van Hagen, Jürgen Cox, Matthias Mann, Jens Andersen<br />

11.00-12.30 S12 Computational Approaches To Mine Proteomic Data room: Forum<br />

chairpersons: Pavel Pevzner & Anne-Claude Gavin<br />

11.00-11.30 MS-Dictionary: A New Approach to Peptide Identification<br />

Pavel Pevzner (University of California at San Diego, UNITED STATES), Sangtae Kim, Nitin Gupta, Nuno Bandeira<br />

11.30-11.50 A generic strategy for the comprehensive analysis of post-translation modifications<br />

Lukas Mueller (Institute of Molecular Systems Biology, SWITZERLAND), Clementine Klemm,<br />

Christine Carapito, Alex Schmidt, Bruno Domon, Ruedi Aebersold<br />

11.50-12.10 A tag chain method for identification of multiple post-translational modifications<br />

Seungjin Na (University of Seoul, KOREA), Eunok Paek, Jaeho Jeong, Kong-Joo Lee, Heejin Park<br />

12.10-12.30 Unbiased Identification of Post-Translational Modifications Using Novel Maxquant Algorithm<br />

Michael L. Nielsen (Max-Planck-Institute of Biochemistry, Department of Proteomics and Signal Transduction,<br />

GERMANY), Jürgen Cox, Tiziana Bonaldi, Michiel Vermeulen, Matthias Mann<br />

S15 Glycoproteomics room: N-N1-O1-O 11.00-12.30<br />

Chairpersons: Catherine E Costello & Peter Roepstorff<br />

Advances in Mass Spectrometry-Based Methods for Glycoprotein Analysis 11.00-11.30<br />

Catherine E Costello (Boston University School of Medicine, UNITED STATES), Marianna Budnik, Giuseppe Infusini,<br />

Yan Jiang, Elizabeth Palaima, Bo Xie, John F. Cipollo, Mark E. McComb, Peter B. O’Connor, Joseph Zaia<br />

Glycoproteomics: Applications For Stem Cell And Cancer Biomarkers 11.30-11.50<br />

Michael Pierce (Complex Carbohydrate Research Center and UGA Cancer Center, University of Georgia,<br />

UNITED STATES), S Dalton, K Moremen, M Tiemeyer, L Wells, R Orlando, K Abbott, G Alvarez-Manilla, W York<br />

Breast Milk Glycoproteome: A Defence Against Pathogenic Infection? 11.50-12.10<br />

Daniel Kolarich (Macquarie University, AUSTRALIA), Pia Hønnerup Jensen, Nicolle Packer<br />

Pilin Glycosylation, Regulated by Sll0899, is Required for Cyanobacterial Motility 12.10-12.30<br />

Young Hye Kim (Korea Basic Science Institute, KOREA), Jin Young Kim, Se-Young Kim, Jeong Hwa Lee,<br />

Ju Yeon Lee, Eun Sun JI, Young-Ho Chung, Jong Shin Yoo, Young Mok Park<br />

52 53


Full Program details<br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />

14.00-15.30 S16 Chemical Proteomics room: Auditorium<br />

chairpersons: Bernhard Kuster & Huib Ovaa<br />

14.00-14.30 Emerging Chemical Approaches to Studying the Proteome<br />

Bernhard Kuster (Technical University Munich, GERMANY)<br />

14.30-14.50 Selectivity Profiling of Lipid Kinase Inhibitors by Chemical Proteomics<br />

Thilo Werner (Cellzome AG, GERMANY), Dirk Eberhard, Giovanna Bergamini Moore, Yann Abraham,<br />

Andrew Cansfield, Kathryn Bell, Marcus Bantscheff, Gitte Neubauer<br />

14.50-15.10 Chemical Proteomics: Affinity Enrichment and Labelling of Metalloproteases<br />

Rainer Bischoff (University of Groningen, THE NETHERLANDS), Hermen Overkleeft, Henk Kauffman,<br />

Michiel Leeuwenburgh, Theo Klein, Paul Geurink<br />

15.10-15.30 Identification of Calmodulin as a Binding Protein of IHY-153, an Antiproliferative Small Molecule<br />

Hye Jin Jung (Yonsei University, KOREA), Joong Sup Shim, Jungchan Park, Hyun-Joon Ha, Jung-Ho Kim,<br />

Joong-Gon Kim, Ho Jeong Kwon<br />

S<strong>19</strong> Proteomics And Epigenetics room: L 14.00-15.30<br />

Chairpersons: Donald Hunt & Marc Timmers<br />

Innovative Mass Spectrometry Technology for the Study of Chromatin Biology 14.00-14.30<br />

Donald Hunt (University of Virginia, UNITED STATES)<br />

A proteomic screen to decipher the histone code interactome by SILAC-based proteomics 14.30-14.50<br />

Michiel Vermeulen (Max Planck Institute of Biochemistry, GERMANY), Matthias Mann<br />

The Maturation of Histone Modifications after Chromatin Assembly 14.50-15.10<br />

Axel Imhof (Center of Integrated Protein Sciences and Adolf-Butenandt Institute, Ludwig-Maximilians<br />

University of Munich, GERMANY), Annette Scharf, Theresa Barth<br />

Screen for Differential Transcription Factor Binding at Single Nucleotide Polymorphisms 15.10-15.30<br />

Falk Butter (MPI of Biochemistry, GERMANY), Michiel Vermeulen, Matthias Mann<br />

14.00-15.30 S17 Kinase- Protein Substrate Networks room: Forum<br />

Chairpersons: Michael Snyder & Pim Pijnappel<br />

14.00-14.30 Dissecting Complex Phosphorylation Regulatory Networks Using Proteomics Technologies<br />

Michael Snyder (Yale University, UNITED STATES)<br />

14.30-14.50 Dynamic Changes in the ERK1 Interactome Determine Cell Fate Decisions<br />

Alex von Kriegsheim (Beatson Institute for Cancer Research, UNITED KINGDOM), Daniela Baiocchi,<br />

Willy Bienvenut, Andrew Pitt, Walter Kolch<br />

14.50-15.10 Identification of Plk1 Specific Phosphorylation Sites on Spindle Proteins<br />

Anna Santamaria (MPI of Biochemistry, Dept. of Cell Biology, GERMANY), Bin Wang, Rainer Malik,<br />

Sabine Elowe, Erich Nigg, Roman Koerner<br />

15.10-15.30 Casting the Net for Kinases: Systematic Discovery of In Vivo Phosphorylation Networks<br />

Rune Linding (Institute of Cancer Research, UNITED KINGDOM)<br />

S20 Proteomics Of The Nervous Systems room: N-N1-O1-O 14.00-15.30<br />

Chairperson: Jyoti Choudhary<br />

Synapse Proteomics 14.00-14.30<br />

Jyoti Choudhary (Wellcome Trust Sanger Institute, UNITED KINGDOM)<br />

Quantitative Synaptic Proteomics in a Mouse Model for the Fragile X Syndrome 14.30-14.50<br />

Ka wan Li (Department of Molecular and Cellular Neurobiology, VU University Amsterdam, THE NETHERLANDS),<br />

Patricia Klemmer, Oleg I. Klychnikov, Carl D. Holmgren, Huibert D. Mansvelder, <strong>August</strong> B. Smit<br />

The Effects of UBB+1 on the Brain Proteome in a Transgenic Mouse Model 14.50-15.10<br />

Caroline May (Medizinisches-Proteom Center, GERMANY), Thomas Schulenborg, Fred W. van Leeuwen,<br />

Martin Irmler, Rohan de Silva, Walter Schubert, Johannes Beckers, Helmut E. Meyer, Katrin Marcus<br />

The Glioma Cell Surface Signal Transduction Network 15.10-15.30<br />

Thomas Bock (NCCR Neuro Center for Proteomics, Institute of Molecular Systems Biology, Swiss Federal Institute of<br />

Technology (ETH), SWITZERLAND), Andreas Hofmann, Damaris Bausch-Fluck, Bernd Wollscheid<br />

14.00-15.30 S18 Proteomics Of Macromolecular Complexes Room: A<br />

Chairperson: Brian Chait<br />

14.00-14.30 Proteomic Approaches for Analyzing Complex Biological Machines<br />

Brian Chait (The Rockefeller University, University of California, UNITED STATES), F Alber, S Dokudovskaya,<br />

L Veenhoff, W Zhang, D Devos, O Karni-Schmidt, A Suprapto, R Williams, A Sali, MP Rout<br />

14.30-14.50 Novel Chromatin Immunopurification (mCHIP) Approaches for the Mapping of Protein Interactions.<br />

Daniel Figeys (OISB/University of Ottawa, CANADA), Mohamed Abu-Farha, Jean-Philippe Lambert<br />

14.50-15.10 An Integrated Experimental Workflow to Increase Throughput and Data Robustness for Global Analysis<br />

of Human Protein Interaction Networks<br />

Timo Glatter (ETH Zürich, SWITZERLAND)<br />

Plenary 7 The Social Network Of A Cell: Room: Auditorium 16.00-16.45<br />

dynamic Protein Interactions<br />

Anne-Claude Gavin (EMBL Heidelberg, GERMANY)<br />

Chairperson: Richard Simpson<br />

Plenary 8 SIGNALING NUTRIENT limitation room: Auditorium 16.45-17.30<br />

Erin O’Shea (Harvard University, Howard Hughes Medical Institute, UNITED STATES)<br />

chairperson: John Yates<br />

15.10-15.30 Characterizing a Minimal Molecular Machinery<br />

Sebastian Kühner (EMBL Heidelberg, GERMANY)<br />

54 55


Publishing in Proteomics<br />

20.00 - 22.00<br />

Chair: Peipei Ping<br />

Program to be announced.<br />

evening sessions<br />

Challenges/Solutions for Implementing Proteomics into<br />

Clinical Practice - An Open Forum Discussion<br />

20.00 - 22.00<br />

Moderator: Salvatore Sechi, NIDDK, National Institutes of Health, USA<br />

room: A<br />

room: B<br />

Leaders in the field including Denis Hochstrasser, Geneva University and University<br />

Hospital, Daniel W. Chan, Johns Hopkins Medical Institutions, and Christer Wingren,<br />

Lund University will open the discussion addressing the following key questions:<br />

What are the regulatory issues and barriers in the approval/use of biomarkers<br />

as diagnostic and what can we do about it?<br />

What is needed for moving proteomics assays into clinical practice?<br />

How can we foster interaction/collaboration/partnership between clinicians and<br />

basic scientists and the private sector?<br />

Today most diagnostic assays use a single analyte as biomarker or surrogate<br />

endpoint what are the barrier for implementing multi-analyte diagnostic?<br />

Regulatory agencies, private companies, funding agencies, clinicians and proteomics<br />

experts are invited to participate in the discussion and/or present their perspective<br />

in a concise way (no more than 1 slide / 3-5 minutes).<br />

Whether a test is clearly described;<br />

If the true presence or absence of disease can be established for all individuals;<br />

Whether the spectrum of patients with and without disease is adequate;<br />

Whether the assessment of test and disease status is conducted in an unbiased<br />

manner; and<br />

If the test performance is summarized by the important terms of sensitivity and<br />

specificity.<br />

Speakers:<br />

Concept of Validation: Nuts and Bolts of Good Proteomic Study<br />

Sudhir Srivstava, National Cancer Institute<br />

Biomarkers and FDA Regulation of In Vitro Diagnostic Devices<br />

Robert Becker, Food and Drug Administration<br />

Mass Spectrometry-based Platforms for Biomarker Discovery and Verification<br />

Daniel Liebler, Vanderbilt School of Medicine<br />

Reproducibility Testing of Gel-based Proteomics<br />

Hans Voshol, Novartis Institutes for Biomedical Research<br />

Validation in the eyes of a Basic Scientist<br />

John Bergeron<br />

Validation in the eyes of Clinical Scientist<br />

Mathias Uhlén<br />

Summary<br />

Sudhir Srivastava<br />

Workshop on Proteomics Validation<br />

room: L<br />

20.00 - 22.30<br />

What Does Proteomics Validation Mean to the Users, Regulators and Public Health<br />

Professionals?<br />

Chair: Sudhir Srivastava<br />

Objective: The term ‘validation’ is grossly misused. It means different things to<br />

different people, and often not tied with the requirements that are expected by<br />

the regulatory and clinical community. The term has taken a new meaning in light of<br />

high throughput, high dimensional technologies, like proteomics where the number of<br />

features (biomarkers) are much more higher than the number of samples and this<br />

often leads to the over-fitting of the data. This has raised an alarm in the minds<br />

of regulators and clinicians due the potentially high rates of false positive cases.<br />

This symposium will invite clinicians, regulators and basic scientists to discuss their<br />

experience and provide guidance to the proteomic community. The symposium will build<br />

on the concept of validation asks:<br />

56 57


Making the most<br />

of genomics<br />

The Netherlands Genomics Initiative (NGI) aims to get the<br />

best from genomics by providing excellence in genomics.<br />

NGI was established by the Dutch government in 2002 and<br />

is now entering its second phase: 2008-2012. The overall<br />

objective of NGI is to ensure that society and economy<br />

benefit from the breakthroughs enabled by genomics in<br />

important fields like health, agro-food, sustainability,<br />

enabling technologies and society.<br />

Forensic<br />

Genomics Consortium<br />

Netherlands<br />

Netherlands Consortium<br />

for Systems Biology<br />

Celiac Disease Consortium<br />

Netherlands<br />

Metabolomics Centre<br />

Netherlands Consortium<br />

for Healthy Ageing<br />

Centre for Medical<br />

Systems Biology<br />

Kluyver Centre for Genomics<br />

of Industrial Fermentation<br />

16 NGI Genomics Centres in the Netherlands<br />

health | agro-food | sustainability | enabling technologies | society<br />

VIRGO Consortium<br />

Ecogenomics<br />

Consortium<br />

Cancer Genomics Centre<br />

Nutrigenomics<br />

Consortium<br />

Centre for BioSystems<br />

Genomics<br />

Netherlands<br />

Bioinformatics Centre<br />

Centre for Society<br />

and Genomics<br />

Netherlands<br />

Toxicogenomics Centre<br />

Enabling Technologies<br />

Tools to analyse, probe<br />

and explore<br />

Unravelling the complex network of biological<br />

processes that constitute life in all its forms – the<br />

core of modern life sciences research – requires<br />

not only an inquisitive mindset, but also a battery<br />

of high-grade technology platforms.<br />

NGI enables probing into the fascinating world<br />

of biology by initiating, organising and funding<br />

a number of technology centres that are<br />

accessible to the Dutch and international life<br />

sciences community. These centres work on their<br />

own research programmes, develop and<br />

disseminate new technologies, tools and<br />

methods, offer technical support and serve as<br />

training centres for scientists and technicians.<br />

Bioinformatics, proteomics, metabolomics,<br />

toxicogenomics and systems biology are the focus<br />

of NGI’s efforts in technology development.<br />

Meet us at<br />

the HUPO<br />

Exhibition<br />

Booth 9<br />

P.O. Box 93035 – 2509 A A The Hague – The Netherlands | T +31 70 344 0672 | F +31 70 344 0632 | E info@genomics.nl<br />

Be part of the thriving NGI genomics community | visit www.genomics.nl /jobs<br />

Wednesday 20 <strong>August</strong> 2008<br />

Room M Room B Room CD Room EF<br />

Room<br />

N-N1-O1-O<br />

Room Forum Room A Room L<br />

Room<br />

Auditorium<br />

Forum Ground<br />

Floor<br />

location <br />

time <br />

Speaker Ready<br />

Room<br />

Registration &<br />

Information<br />

whole day<br />

Corporate Workshop<br />

Thermo Scientific<br />

Corporate Workshop GE<br />

Healthcare<br />

Corporate Workshop<br />

Rosetta Bio<strong>software</strong><br />

07.00 - 07.50<br />

08.00 - 08.45 Sung-Hou Kim<br />

08.45 - 09.30 John Yates<br />

09.30 - 11.00 Break & Posters in Exhibition Hall 10<br />

S25<br />

Structural<br />

Proteomics<br />

S24<br />

Assembling the parts:<br />

Whole Cell Modelling /<br />

Biomarkers 1<br />

S23<br />

Array Based<br />

Proteomics<br />

S22<br />

Quantification<br />

S21<br />

Integration and<br />

storage of<br />

proteomics data<br />

11.00 - 12.30<br />

Corporate Workshop<br />

Invitrogen<br />

Corporate Workshop<br />

Bio-Rad Laboratories<br />

Corporate Workshop<br />

Waters<br />

12.30 - 14.00 Lunch, Poster Session & Exhibition in Exhibition Hall 10<br />

S30<br />

Proteome biology of<br />

infectous diseases<br />

S29<br />

Single cell imaging/<br />

HUPO Young<br />

Investigator Awards<br />

S28<br />

Biomarkers 2<br />

S27<br />

Cancer related signaling<br />

S26<br />

Stem cell<br />

proteome biology<br />

14.00 - 15.30<br />

15.30 - 16.00 Break & Posters in Exhibition Hall 10<br />

HUPO 2008<br />

Award Session<br />

16.00 - 17.30<br />

Announcement HUPO<br />

2009 & Closing<br />

17.30 - 18.00<br />

<strong>19</strong>.00 - 23.00 Congress Dinner<br />

Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />

= Initiative = Other meeting<br />

58 59


Plenary Speakers Wednesday<br />

Sung-Hou Kim<br />

John Yates<br />

BIOGRAPHY<br />

Sung-Hou Kim is a professor in the Department of Chemistry, University of California,<br />

Berkeley, CA (UCB), and a Senior Faculty Scientist at Lawrence Berkeley National<br />

Laboratory (LBNL), Berkeley, CA. He currently serves as the Director of the Berkeley<br />

Structural Genomics Center, LBNL, and the Head of the Structural Biology Department,<br />

Physical Biosciences Division, LBNL. He is a member of the U. S. National Academy of<br />

Sciences, and a fellow of the American Academy of Arts and Sciences. His research<br />

interest has been in Structural Biology, Structural Genomics, Computational Genomics,<br />

and Drug Discovery.<br />

Abstract<br />

Demography and Phylogeny of Structural and Sequence Proteomes<br />

S.-H. Kim, S.-R. Jun, G.A. Wu, and G.E. Sims, Univ. of California and Lawrence Berkeley<br />

National Laboratory, Berkeley CA 94720 USA<br />

A large number of 3-D structures of proteins became available by the recent<br />

development of structure determination technology during the last two decades. There<br />

are a few “minimal organisms,” for which over 95% of the soluble, globular proteins<br />

may now be assigned their structural folds. Near-complete structural proteome of one<br />

minimal organism is analyzed as they relate to protein functions and fold usage among<br />

functional categories. The structural proteome of the organism is then “mapped”<br />

on the protein structure universe, a collection of all known protein structures. This<br />

“mapping” reveals features that may be interpretable in terms of evolution of protein<br />

structure and function.<br />

Similarly, a large number of whole genome sequences and individual gene sequences<br />

became available by the explosive development of sequencing technology during the<br />

last two decades. Currently, most comparison methods rely on the multiple sequence<br />

alignment of one or more common genes among the population examined, and do not<br />

utilize the whole genome sequences. We have developed alignment-free methods to<br />

compare and organize whole genome sequences (coding and non-coding regions) or<br />

whole genome coding sequences (sequence proteomes). The methods allow us to map<br />

“demography” of organisms represented by whole genome sequences or whole genome<br />

coding region sequences. Such mapping can provide a global view of distribution and<br />

relationship among the demographic groups of organisms, and possibly their evolution.<br />

Funded by NIH (P50 GM62412)<br />

BIOGRAPHY<br />

John Yates received his Ph.D. in Chemistry at the University of Virginia under Professor<br />

Donald Hun and is now a Professor in the Department of Chemical Physiology at The<br />

Scripps Research Institute. His research interests include development of integrated<br />

methods for tandem mass spectrometry analysis of protein mixtures, bioinformatics<br />

using mass spectrometry data, and proteomics.<br />

Abstract<br />

Driving Biological Discovery Using Quantitative Mass Spectrometry<br />

John R. Yates<br />

Department of Chemical Physiology, 10550 North Torrey Pines Road, SR11, The Scripps<br />

Research Institute, LaJolla, CA 92037 USA<br />

A component to understanding biological processes involves identifying the proteins<br />

expressed in cells as well as their modifications and the dynamics of processes. Several<br />

major technologies, but especially mass spectrometry, have benefited from large-scale<br />

genome sequencing of organisms. The sequence data produced by these efforts can<br />

be used to interpret mass spectrometry data of proteins and thus enables rapid and<br />

large-scale analysis of protein data from experiments. Advances in multi-dimensional<br />

separations as well as mass spectrometry have improved the scale of experiments<br />

for protein identification. This has improved the analysis of protein complexes, and<br />

more complicated protein mixtures. Quantitative mass spectrometry can be used to<br />

study biological processes such as development or the effects of gene mutations on<br />

pathways. Methods to improve the sample preparation, separation of peptides and<br />

analysis of the data will be described as well applications of shotgun proteomics to the<br />

study biological processes.<br />

60 61


Full Program details<br />

Wednesday 20 <strong>August</strong><br />

8.00-8.45 Plenary 9 Demography and Phylogeny of Structural Room: Auditorium<br />

and Sequence Proteomes<br />

Sung-Hou Kim (University of California Berkeley, Lawrence Berkeley National<br />

laboratory, UNITED STATES), Se-Ran Jun, G Albert Wu, Gregory E. Sims<br />

Chairperson: Brian Chait<br />

8.45-9.30 Plenary 10 Driving Biological Discovery Using Quantitative Room: Auditorium<br />

Mass Spectrometry<br />

John Yates (The Scripps Research Institute, UNITED STATES)<br />

Chairperson: Don Hunt<br />

S23 Array Based Proteomics room: A 11.00-12.30<br />

Chairperson: Joshua LaBaer<br />

Functional Proteomics for Biomarker and Target Discovery 11.00-11.30<br />

Joshua LaBaer (Harvard Medical School, UNITED STATES)<br />

Proteome Microarray Analysis of the Antibody Response to Infectious Diseases 11.30-11.50<br />

Robert Ulrich (Army Medical Research Institute of Infectious Diseases, UNITED STATES), Sarah Keasey,<br />

James Meagan, Alexander Tikhonov, Barry Schweitzer<br />

PDMS-Based Protein Chips for Proteomics 11.50-12.10<br />

Wang-Chou Sung (National Cheng kung University, TAIWAN), Makamba Honest, Shu-Hui Chen<br />

Antibody Microarrays – A Way to Define Predictive Biomarker Signatures in Cancer 12.10-12.30<br />

Carl Borrebaeck (Lund University, SWEDEN)<br />

11.00-12.30 S21 Integration And Storage Of Proteomics Data room: Auditorium<br />

Chairpersons: Rolf Apweiler & Bas van Breukelen<br />

11.00-11.30 Bioinformatics Infrastructure for Proteomics: Status of Database and Standards Development<br />

Rolf Apweiler (EMBL-EBI, UNITED KINGDOM)<br />

11.30-11.50 Design and Implementations of the New PSI Mass Spectrometer Output File Standard: mzML 1.0<br />

Eric W. Deutsch (Institute for Systems Biology, United States), Lennart Martens, Joshua Tasman, Jim<br />

Shofstahl, Darren Kessner, Matthew Chambers, Fredrik Levander, Puneet Souda, Luisa Montecchi-Palazzi,<br />

Henning Hermjakob, Pierre Alain Binz<br />

11.50-12.10 The PRIDE Database: Better, Faster, Stronger<br />

Richard Cote (European Bioinformatics Institute, UNITED KINGDOM), Phil Jones, Lennart Martens,<br />

Juan Antonio Vizcaino, Henning Hermjakob<br />

12.10-12.30 ProHits - A Complete LIMS System For Functional Proteomics<br />

Frank Liu (Centre for Systems Biology, Samuel Lunenfeld Research Institute, CANADA), Jian Ping Zhang,<br />

Brett Larsen, Ashton Breitkreutz, Zhen-Yuan Lin, Jim Woodgett, Tony Pawson, Jeff Wrana,<br />

Anne-Claude Gingras, Mike Tyers<br />

S24 Assembling The Parts: Whole Cell Modelling + Biomarkers 1 room: L 11.00-12.30<br />

Chairperson: Rob Russell<br />

New Peptides Mediating Interaction Networks: From Two-hybrid Networks to 3D Structure 11.00-11.30<br />

Rob Russell (EMBL, GERMANY)<br />

Formlin-fixed Paraffin Embedded (FFPE) Clinical Proteome Initiative of Lung Cancer 11.30-11.50<br />

Toshihide Nishimura (Tokyo Medical University, JAPAN), Masaharu Nomura, Sayaka Mikami, Hiroko Endo,<br />

Yasuhiko Bando, Ryotaro Nishiyama, Kiyonaga Fujii, Sumie Ando, Hiroko Hamazaki, Harubumi Kato<br />

Naturally Occurring Urinary Peptides for Differential Diagnosis of Chronic Kedney Disease 12.10-12.30<br />

Harald Mischak (Mosaiques-Diagnostics, GERMANY), Kasper Rossing, Jan Novak, Bruce A. Julian,<br />

Moritz Frommberger, Eric Schiffer, Philippe Schmitt-Kopplin<br />

Oligosaccharide Microarrays and Prospects for Deciphering the Glyco-code 11.50-12.10<br />

Ten Feizi (Imperial College, united kingdom)<br />

11.00-12.30 S22 Quantification Room: Forum<br />

Chairpersons: Shu-Hui Chen & Chris de Koster<br />

11.00-11.30 Quantitative Nano-Proteomics Using Stable Isotope Dimethyl Labeling - Resolving Protein Complexes<br />

related to Estrogen Action<br />

Shu-Hui Chen (National Cheng Kung University, TAIWAN)<br />

11.30-11.50 Triplex Stable Isotope Dimethyl Labeling and its Application in Chemical Proteomics<br />

Paul Boersema (Utrecht University, THE NETHERLANDS), Thin Thin Aye, Toon van Veen, Albert Heck,<br />

Shabaz Mohammed<br />

11.50-12.10 MRM Analysis of Tumor Homogenates for Absolute Quantification of Potential Biomarkers<br />

Leroi DeSouza (CRMS York University, CANADA), Marjorie Minkoff, Terence Colgan, Alexander Romaschin,<br />

KW Michael Siu<br />

12.10-12.30 Proteome-wide Accurate Label-free Quantitation of Mammalian Cells<br />

Juergen Cox (Max Planck Institute of Biochemistry, GERMANY), Christian Luber, Matthias Mann<br />

S25 Structural Proteomics room: N-N1-O1-O 11.00-12.30<br />

Chairpersons: Cheryl Arrowsmith & Rolf Boelens<br />

Integrating Structural Genomics and Chemical Genomics for Biology and Medicine 11.00-11.30<br />

Cheryl Arrowsmith (Structural Genomics Consortium, CANADA)<br />

Visual Proteomics of the Human Pathogen Leptospira Interrogans 11.30-11.50<br />

Martin Beck (Swiss Federal Institute of Technology, SWITZERLAND), Johan Malmstroem, Vinzenz Lange,<br />

Alexander Schmidt, Eric Deutsch, Ruedi Aebersold<br />

Interactome and Interface Protocol - 2 nd Generation Strategy for Topology Mapping of Protein Complexes 11.50-12.10<br />

Gerold Schmitt-Ulms (University of Toronto, CANADA)<br />

Intramolecular Interactions Within Voltage/Ca2+ Gated K+ Channels: Structure/Function Implications 12.10-12.30<br />

Sarah Warburton (University of California Los Angeles, UNITED STATES), Taleh Yusifov, Thomas Vondriska,<br />

Riccardo Olcese<br />

62 63


Full Program details<br />

Wednesday 20 <strong>August</strong><br />

14.00-15.30 S26 Stem Cell Proteome Biology room: Auditorium<br />

Chairperson: Jeroen Krijgsveld<br />

14.00-14.30 Quantitative Phospho-proteomics of Human Embryonic Stem Cell Differentiation<br />

Jeroen Krijgsveld (Utrecht University, THE NETHERLANDS), Javier Muñoz, Dennis Van Hoof, Martijn Pinkse,<br />

Stefan Braam, Bas van Breukelen, Christine Mummery, Albert Heck<br />

14.30-14.50 Tracking Patterns of Post-translational Modification on Histone H4 During Differentiation of Human ES Cells<br />

Justin Brumbaugh (University of Wisconsin, UNITED STATES)<br />

14.50-15.10 Metabolic Labeling and Click Chemistry Detection of Stem Cell Markers<br />

Brian Agnew (Molecular Probes-Invitrogen, UNITED STATES), Courtenay Hart, Mahbod Hajivandi,<br />

Marshall Pope, Lucas Chase<br />

15.10-15.30 Quantitative Analysis of the Mesenchymal Stem Cell Secretome during Osteogenesis<br />

Lars Kristensen (University of Southern Denmark, DENMARK), Moustapha Kassem, Jens Andersen<br />

14.00-15.30 S27 Cancer Related Signaling room: Forum<br />

Chairpersons: Connie Jimenez & Monique Slijper<br />

14.00-14.30 Proteomics Targeted to Sub-cellular Compartments and Secretomes for Discovery of Signaling<br />

pathways in Colorectal Cancer<br />

Connie Jimenez (VU University Medical Center, THE NETHERLANDS), Jakob Albrethsen, Remond Fijneman,<br />

Jaco Knol, Sander Piersma, Meike de Wit, Sandra Mongera, Beatriz Carvalho, Gerrit Meijer<br />

14.30-14.50 Addressing the Angiogenic Switch by Studying Tumor-host Interactions in a Model of Glioma<br />

Uros Rajcevic (NorLux Neuro-oncology, CRP-Sante, LUXEMBOURG), Jaco C. Knol, Maarten Loos, KaWan Li,<br />

Oleg Klychnikov, Rolf Bjerkvig, Thang V. Pham, Kjell Petersen, Connie R. Jimenez, Simone P. Niclou<br />

14.50-15.10 Multiplex Substrate Degradomics of Matrix Metalloproteinases in Breast Carcinogenesis<br />

Ulrich auf dem Keller (Centre for Blood Research, University of British Columbia, CANADA), Anna Prudova,<br />

Yuanmei Lou, Shoukat Dedhar, Christopher Overall<br />

15.10-15.30 Phosphoproteomics Analysis Reveals Divergent Signaling for Oncogenic FLT3 Mutants<br />

Yi Zhang (Dana-Farber Cancer Institute, UNITED STATES), Manor Askenazi, Chance Luckey, Jarrod Marto<br />

14.00-15.30 S28 Biomarkers 2 Room: A<br />

Chairperson: Richard Simpson<br />

14.00-14.30 Secretome-based Proteomic Strategies for Uncovering New Biomarkers for Colorectal Cancer<br />

Richard Simpson (Ludwig Institute for Cancer Research & Walter and Eliza Hall Institute of Medical Research,<br />

AUSTRALIA), Justin Lim, Eugene Kapp, Bow Tauro, Thomas Barnes, Oliver Bernhard, Robert Moritz<br />

14.30-14.50 Cell-based Proteome Analysis: The First Stage in the Pipeline for Biomarker Discovery<br />

Barbara Sitek (Medizinisches Proteom-Center, Ruhr Universität Bochum, GERMANY), Gereon Poschmann,<br />

Corinna Henkel, Bence Sipos, Oliver Vonend, Helmut E. Meyer, Kai Stühler<br />

14.50-15.10 The Use of Plasma Proteomics to Study Disease Pathogenesis<br />

William Hancock (Northeastern University, UNITED STATES), Marina Hincapie, Majlinda Kullolli,<br />

Tatiana Plavina<br />

15.10-15.30 Shotgun Proteomics of Human Gastric Juice<br />

Maxey Ching Ming Chung (Department of Biochemistry, Yong Loo Lin School of Medicine, Department of<br />

Biological Sciences, Faculty of Science, National University of Singapore, SINGAPORE), Cynthia R.M.Y. Liang,<br />

Qingsong Lin, Sandra Tan, Teck Kwang Lim, Yi Liu, Khay Guan Yeoh, Jimmy So, Choy Leong Hew<br />

S29 Single Cell Imaging + HUPO YIP room: L 14.00-15.30<br />

Chairpersons: Philippe Bastiaens & John Yates<br />

Imaging Reaction Dynamics For Cellular Systems Biology 14.00-14.30<br />

Philippe Bastiaens (MPI for Molecular Physiology, Dept. of Systemic Cell Biology, GERMANY)<br />

A Systems View of the Cell Cycle by Parallel Quantitation of Proteome and Phosphoproteome 14.30-14.50<br />

Jesper V. Olsen (Max-Planck-Institute for Biochemistry, GERMANY), Michiel Vermeulen, Anna Santamaria,<br />

Chanchal Kumar, Florian Gnad, Jürgen Cox, Erich Nigg, Matthias Mann<br />

Exploring Different Enzymes to Allow Facile Peptide Sequencing by ETD 14.50-15.10<br />

Shabaz Mohammed (Biomolecular Mass Spectrometry and Proteomics Group, Bijvoet Center for Biomolecular<br />

Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, THE NETHERLANDS),<br />

Nadia Taouatas, Kristina Lorenzen, Madalina Drugan, Alessandro Vannini, Patrick Cramer, Albert Heck<br />

New Targets of Snake Venom Metalloproteinases Revealed by Proteomic Approaches 15.10-15.30<br />

Adriana Paes Leme (Instituto Butantan, BRAZIL), Marina Assakura, Antonio Camargo, Nicholas Sherman,<br />

Jay Fox, Solange Serrano<br />

S30 Proteome Biology Of Infectious Diseases room: N-N1-O1-O 14.00-15.30<br />

Chairpersons: Young-Ki Paik & Paul Hensbergen<br />

Proteome Biology of Candida albicans Infection and Action Mechanism of Antifungal Agents 14.00-14.10<br />

Young-Ki Paik (Yonsei Proteome Research Center, Yonsei University, KOREA), Hyoung-Joo Lee,<br />

Jong Shin Yoo, Ki-Young Kim, Yu-Kyong Shin<br />

Proteomics Applied to the Study of Hepatitis C Virus Pathogenesis 14.10-14.30<br />

Romain Parent (Fred Hutchinson Cancer Research Center, UNITED STATES), Sufen Shang, Neha Lohia,<br />

Laura Beretta<br />

Proteolytic Processing of the Campylobacter Adherence Factor (CadF) in Campylobacter Jejuni 14.30-14.50<br />

Stuart Cordwell (University of Sydney, AUSTRALIA), Nichollas Scott<br />

Proteomics of Influenza Virus and Vaccine 14.50-15.10<br />

Michail Alterman (FDA/CBER/OCTGT/TVBB, UNITED STATES), Melkamu Getie-Kebtie, Maryna Eichelberger<br />

Phosphoproteome of Primary Human Host Cells Infected with Yersinia pestis 15.10-15.30<br />

Ramin Hakami (USAMRIID, UNITED STATES)<br />

Eupa and HUPO Awards session room: Auditorium 16.00-17.30<br />

Introduction by Albert Heck 16.00-16.05<br />

Amsterdam Young Scientist Award 16.05-16.15<br />

Awardee: To Be Announced (TBA)<br />

EuPA Senior Scientist Award in Proteomic Sciences 16.15-16.20<br />

Elsevier representative: Adriaan Klinkenberg · Eupa representative: EuPA President · Awardee: Stellan Hjerten<br />

Announcement Eupa Ph.D. Award 16.20-16.25<br />

Elsevier representative: Adriaan Klinkenberg · Eupa YIP representative: Concha Gil<br />

Awardees: TBA, selected after their presentation<br />

HUPO YIP Prize announcement 16.25-16.30<br />

HUPO representative: Pierre Legrain · HUPO YIP representative: John Yates<br />

Awardees: Jesper Olsen, Shabaz Mohammed, Adriana Paes Leme<br />

HUPO Discovery in Proteomic Sciences award 16.30-16.35<br />

HUPO representative: Pierre Legrain · Awardee: Catherine Costello<br />

HUPO Distinguished Service Award 16.35-16.40<br />

HUPO representative: Pierre Legrain and Rolf Apweiler · Awardee: Richard Simpson<br />

HUPO Distinguished Achievement Award 16.40-17.00<br />

JPR Representative: TBA · HUPO representative: Pierre Legrain and Rolf Apweiler · Awardee: Denis Hochstrasser<br />

HUPO Distinguished Achievement Award 17.00-17.30<br />

JPR Representative: TBA · HUPO representative: Pierre Legrain and Rolf Apweiler · Awardee: Matthias Mann<br />

64 65


Poster topics<br />

Monday 18 <strong>August</strong><br />

wednesday 20 <strong>August</strong><br />

Topics<br />

Poster Numbers<br />

Topics<br />

Poster Numbers<br />

Biomarkers I<br />

P-MON-001 - P-MON-126<br />

Array Based Proteomics<br />

P-WED-001 - P-WED-028<br />

Innovation In Peptide & Protein Seperation<br />

Technologies<br />

Molecular Mass Imaging<br />

Organelle and biological membranes<br />

Proteomics<br />

Quantification I<br />

Reagents for proteomics<br />

Standards for Clinical Proteomics<br />

Stem cell proteome biology<br />

Structural Proteomics<br />

P-MON-127 - P-MON-186<br />

P-MON-187 - P-MON-204<br />

P-MON-205 - P-MON-267<br />

P-MON-268 - P-MON-303<br />

P-MON-304 - P-MON-318<br />

P-MON-3<strong>19</strong> - P-MON-330<br />

P-MON-331 - P-MON-353<br />

P-MON-354 - P-MON-370<br />

Biomarkers III<br />

Cardiovascular Proteome Biology<br />

Integration and storage of proteomics data<br />

Kinase-protein substrate networks<br />

Proteome biology of infectious diseases<br />

Proteomics and epigenetics<br />

Proteomics of the nervous systems<br />

Quantification II<br />

Other<br />

P-WED-029 - P-WED-101<br />

P-WED-102 - P-WED-143<br />

P-WED-144 - P-WED-166<br />

P-WED-167 - P-WED-171<br />

P-WED-172 - P-WED-208<br />

P-WED-209 - P-WED-217<br />

P-WED-218 - P-WED-251<br />

P-WED-252 - P-WED-291<br />

P-WED-292 - P-WED-355<br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />

Topics<br />

Alternative splicing & protein processing<br />

Biomarkers II<br />

Poster Numbers<br />

P-TUE-001 - P-TUE-014<br />

P-TUE-015 - P-TUE-040<br />

C. elegans and Drosophila P-TUE-041 - P-TUE-048<br />

Cancer related signaling<br />

Chemical Proteomics<br />

Computational approaches to mine<br />

proteomic data<br />

Glycoproteomics<br />

Mass Spectrometric Innovations<br />

Phosphoproteomics<br />

Plant proteomics<br />

Proteomics of Macromolecular Complexes<br />

Yeast proteomics; sparks for new biology<br />

P-TUE-049 - P-TUE-110<br />

P-TUE-111 - P-TUE-135<br />

P-TUE-136 - P-TUE-<strong>19</strong>3<br />

P-TUE-<strong>19</strong>4 - P-TUE-225<br />

P-TUE-226 - P-TUE-250<br />

P-TUE-251 - P-TUE-306<br />

P-TUE-307 - P-TUE-322<br />

P-TUE-323 - P-TUE-362<br />

P-TUE-363 - P-TUE-370<br />

66 67


Poster Listing<br />

Monday 18 august<br />

Biomarkers I<br />

P-MON-001<br />

P-MON-002<br />

P-MON-003<br />

P-MON-004<br />

Targeting Serum Glycoprotein Cancer Biomarkers With Click Chemistry<br />

Courtenay Hart (Molecular Probes-Invitrogen, UNITED STATES), Brian Agnew,<br />

Tamara Nyberg, Mahbod Hajivandi, Marshall Pope, Rajkumar Lakshmanaswamy<br />

Glycoproteome Analysis In Human Plasma Using Multi-Lectin Affinity Column And<br />

Lc-Ms/Ms For The Discovery Of Potential Diabetic Nephropathy Biomarkers<br />

Jung-Mo Ahn (Department of Biochemistry, School of Dentistry Kyungpook National<br />

University, KOREA), Byung-kyu Kim, Ji-hyun Lee, Hye-sim Cho, In-Kyu Lee, Je-Yoel Cho<br />

Evaluation Of Correlation Between Cyfra 21-1 And Cea With Telomerase Activity<br />

In Lung Cancer Patients And Healthy Controls<br />

Behrang Alani (Department of Physiology and Pharmacology, School of Medicine,<br />

Kashan University, IRAN), Khalil Ansarin, Massood Nazemieh, Mahdi Noureddini,<br />

Abbas Mohajeri, Amir Reza Amir Hejri<br />

Comparative Proteomic Study Of The Human Erythrocyte ‘Ghost’ Microsomal<br />

Fraction In Copd<br />

Bruno Alexandre (Laboratorio Proteomica, Dept. Genetica Humana INSA, I.P.,<br />

PORTUGAL / Laboratory of Proteomics and Analytical Technologies, SAIC-Frederick<br />

Inc., National Cancer Institute at Frederick, USA), Nuno Charro, Antonio Bugalho de<br />

Almeida, Timothy Veenstra, Josip Blonder, Deborah Penque<br />

P-MON-011<br />

P-MON-012<br />

P-MON-013<br />

P-MON-014<br />

P-MON-015<br />

P-MON-016<br />

Identification Of Protein Expressed By Aortic Stenosis Valves In The Search For<br />

Novel Biomarkers<br />

Felix Gil-Dones (Laboratorio de Fisiopatología Vascular. Hospital Nacional de Parapléjicos.<br />

SESCAM., SPAIN), Tatiana Martin-Rojas, Natacha Diaz-Prieto, Luis F. Lopez-Almodovar,<br />

Fernando de la Cuesta, Gloria Alvarez-llamas, Fernando Vivanco, Luis R. Padial,<br />

Maria G. Barderas<br />

Biomarkers For Tse Disease:- Seldi-Tof Approach<br />

Janice Barr (Roslin Institute / NPU, UNITED KINGDOM), Michael Watson, Nathan<br />

Harris, James W. Ironside, Mark W. Head, Rona Barron<br />

A Proteomic Approach To The Identification Of Stress Biomarkers For Bovine<br />

And Porcine Livestock<br />

Anna Bassols (Universitat Autonoma de Barcelona, SPAIN), Anna Marco, Yolanda Saco,<br />

Jose Luis Ruiz de la Torre, Alex Bach<br />

Development Of Specific Silicon Chips And Magnetic Nanobeads For Low And No<br />

Invasive Brain “Micro-Nanoproteomic”<br />

François Berger (INSERM U 836 Brain Nanomedicine Group, FRANCE), Ali Bouamrani,<br />

Affif zacaria, Claire Ramus, David Ratel, Maryline Cosnier, Patrice Caillat, Stephan Chabardes<br />

Ranking Of Soluble-Secreted Proteins (Rssp): A Biomarker Strategy For Colon Cancer<br />

Oliver Bernhard (Ludwig Institute for Cancer Research / The Walter and Eliza Hall<br />

Institute, AUSTRALIA), Richard Simpson<br />

Prenatal Bisphenol - A Exposure Alters The Mammary Gland Proteome In<br />

Prepubertal And Adult Rats<br />

Angela Betancourt (University of Alabama at Birmingham, UNITED STATES), Coral<br />

Lamartiniere<br />

P-MON-005<br />

P-MON-006<br />

P-MON-007<br />

P-MON-008<br />

P-MON-009<br />

Biomarkers For Hypertension - Relationship Between Body Fluids And Tissue<br />

Heather Allingham (Glasgow University, UNITED KINGDOM), Richard Goodwin, Martin<br />

McBride, Carsten Baessrmann, Markus Lubeck, Andrew Pitt<br />

Prohibitin Isoforms In Colorectal Cancer: A Proteomic Study<br />

Paula Álvarez Chaver (Universidad De Vigo, Spain), Francisco Javier Rodríguez<br />

Berrocal, María Páez De La Cadena, Ana María Rodríguez Piñeiro, Vicenta Soledad<br />

Martínez Zorzano<br />

Proteins Potentially Involved In F508del-Cftr Trafficking Restoration Process<br />

Patricia Alves (Laboratorio de Proteomica, Dept. de Genética Humana, INSA-IP /<br />

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, PORTUGAL),<br />

Ana Coelho, Francisco Couto, Paulo Nogueira, Deborah Penque<br />

Effect Of Lipid Peroxidation On Proteome Of The Hela Cell Line<br />

Sandro Argüelles Castilla (Dpto Bioquímica, Facultad de Farmacia-Universidad de<br />

Sevilla, SPAIN), Alberto Machado, Antonio Ayala<br />

Comparison Of Protein Profiles With Gene Expression Data To Select Biomarker<br />

Candidates For Estrogen Receptor Negative Breast Cancer<br />

Ji-Yeon Bae (Cancer Research Institute, Seoul National University College of<br />

Medicine, KOREA), Jong Won Lee, Wonshik Han, Jae Kyo Yi, Eun-Mi Jeong, Dong Hyun<br />

Kim, Cheolju Lee, Myeong-Hee Yu, Dong-Young Noh<br />

P-MON-017<br />

P-MON-018<br />

P-MON-0<strong>19</strong><br />

P-MON-020<br />

P-MON-021<br />

P-MON-022<br />

Comparison Of Cerebrospinal Fluid Proteins In Igg Fractions From Normal And<br />

Multiple Sclerosis Patients<br />

Natascha Helena Beyer (Statens Serum Institut, DENMARK / University of Victoria<br />

Genome BC Proteomics Centre, CANADA), Darryl Hardie, Leanne Britt Ohlund,<br />

Jette Lautrup Frederiksen, Christoph H. Borchers, Niels H.H. Heegaard<br />

Analysis Of Human Follicular Fluid Proteins By Isoelectric Focusing Fractionation<br />

Coupled To Mass Spectrometry<br />

Karel Bezstarosti (Erasmus MC, THE NETHERLANDS), Regine Steegers-Theunissen,<br />

Jeroen Demmers<br />

Withdrawn<br />

Proteins In Exhaled Breath Condensate: Identification And Pattern<br />

Karolien Bloemen (Flemish Institute for Technological Research (VITO), Environmental<br />

Toxicology, BELGIUM), Erwin Witters, Jef Hooyberghs, Kristine Desager, Greet Schoeters<br />

Comparative Proteomic Analysis Of Human Lung Cancer<br />

Butt Kwok Chu (Department of Applied Biology and Chemical Technology, The Hong Kong<br />

Polytechnic University, CHINA), CS Cho, SK Au, Leung Woon Fong, Zu Hai Long, Lo<br />

Chun Lap<br />

Withdrawn<br />

P-MON-010<br />

Overexpressed Proteins In Follicular Fluid From Infertile Patients Undergoing Ivf<br />

Therapy<br />

Kwang-Hyun Baek (Pochon CHA University, KOREA), Yong-Soo Kim, Myung-Sun Kim,<br />

Bum-Chae Choi, Sang-Jin Song, Dong-Hyun Cha<br />

P-MON-023<br />

P-MON-024<br />

Withdrawn<br />

Comprehensive Proteomic Analysis Of The Endometrial Fluid Aspirate<br />

Juan Casado-Vela (CICBiogune. Proteomics Unit. Technology Park of Bizkaia, SPAIN),<br />

Eva Rodriguez-Suarez, Juan Antonio García-Velasco, Roberto Matorras, Sandra<br />

González, Amagoia Ametzazurra, Daniel Nagore, Jose M. Mato, Felix Elortza<br />

68 69


P-MON-025<br />

Quantitative Analysis Of Malignant Pleural Mesothelioma Cell Surface Proteins<br />

Ferdinando Cerciello (Institute for Molecular Systems Biology, ETH Zurich,<br />

SWITZERLAND), Bernd Wollscheid, Damaris Bausch-Fluck, Colette Bigosch, Reto Ossola,<br />

Rolf Stahel, Ruedi Aebersold, Annemarie Ziegler<br />

P-MON-037<br />

Ultra-Sensitive Analysis Of Cancer Leakage Biomarkers Using The Proximity<br />

Ligation Technology<br />

Spyros Darmanis (Uppsala University, SWEDEN), Ulf Landegren, Masood Kamali-<br />

Moghaddam, Anders Alderborn<br />

P-MON-026<br />

P-MON-027<br />

P-MON-028<br />

Serum Proteome Profiling Of Cystic Fibrosis Patients: A 2de-Ms And Lc-Ms/Ms<br />

Approach<br />

Nuno Charro (Laboratorio Proteomica, Deptº. Genetica Humana INSA, PORTUGAL<br />

/ Clinical Proteomics Facility, University of Pittsburgh Medical Centre, USA), Bruno<br />

Alexandre, Paula Pacheco, António de Almeida, Thomas Conrads, Deborah Penque<br />

Identification Of Disease Regulated Serum Proteins In Lung Cancer Of C-Myc<br />

And C-Raf Transgenic Mice<br />

Bijon Chatterji (Fraunhofer ITEM, GERMANY), Juergen Borlak<br />

Hsp27 And Prx-2: Potential Clinical Biomarkers For Barrett’s Esophagus Early<br />

Detection, Therapy And Prognosis<br />

Yan Cheng (Department of Gastroenterology, CHINA), Jun Zhang<br />

P-MON-038<br />

P-MON-039<br />

P-MON-040<br />

Integration Of Proteomics And Genomics To Identify Biomarkers For Colon Cancer<br />

Meike de Wit (Department of Pathology, VU University medical center, THE<br />

NETHERLANDS), Connie R. Jimenez, Beatriz Carvalho, Sander Piersma, Rolf<br />

Lamerichs, Gerrit A. Meijer, Remond J.A. Fijneman<br />

Peptidome Profiling Of Ovarian Cancer By Maldi-Tof/Ms<br />

Anna Della Corte (‘John Paul II’ Center-Catholic University, ITALY), Marco D’Imperio,<br />

Michela Di Michele, Maria De Ninno, Maria Benedetta Donati, Domenico Rotilio<br />

Cell Surface Protein Profiling And Identification Of Galectin-1 As A Potential Renal<br />

Cell Carcinoma Biomarker Using Cell Culture On Proteinchip And Maldi-Tof Ms<br />

Hassan Dihazi (Nepehrology & Rheumatology, Medical Center Goettingen, GERMANY),<br />

Claudia Mueller, Abdul R. Asif, Thomas Flad, Abderrahim Elmaouhoub, Gerhard A. Mueller<br />

P-MON-029<br />

P-MON-030<br />

P-MON-031<br />

P-MON-032<br />

P-MON-033<br />

P-MON-034<br />

P-MON-035<br />

P-MON-036<br />

Quantitative Proteomic Analysis Of Human Amniotic Fluid<br />

Chan-Kyung J. Cho (University of Toronto, Mount Sinai Hospital, CANADA),<br />

Christopher Smith, Elizabeth Winsor, Eleftherios Diamandis<br />

Comparison Of Secreted Protein Expression From Hepg2 Cells Exposed To<br />

Benzo(A)Pyrene And Benz(A)Anthracene<br />

Seonyoung Choi (Korea University, KOREA), Zhi Zheng, Eunkyung Cho, Ji-Young Lee,<br />

Min Lee, So-Young Park, Donggeun Sul<br />

An Optimized Time Alignment Algorithm: Cow Using Coda-Selected Mass<br />

Chromatograms<br />

Christin Christin (Department of Analytical Biochemistry, University of Groningen,<br />

THE NETHERLANDS), Age Smilde, Huub Hoefsloot, Frank Suits, Rainer Bischoff,<br />

Peter Horvatovich<br />

Proteomic Profiling Of Normal Human Tears<br />

CY Chu (The Chinese University of Hong Kong, CHINA), JCF Pong, TCW Poon, CC<br />

Wang, CP Pang<br />

Identification Of Potential Biomarkers For The Detection Of Breast Cancer By<br />

Seldi-Tof Ms<br />

Liping Chung (Kolling Institute of Medical Research, University of Sydney, AUSTRALIA),<br />

Sabah Shibli, Deborah Marsh, Katrina Moore, Robert Baxter<br />

Identification And Characterization Of New Blood-Accessible Colorectal Cancer<br />

Biomarkers<br />

Paolo Conrotto (ETHZ, SWITZERLAND), Jascha Rybak, Dario Neri, Philippe Kischel,<br />

David Waltregny, Vincent Castronovo<br />

Identification Of Differentially Expressed Plasma Membrane Proteins In Renal<br />

Cancer<br />

Vassilis Aggelis, Rachel Craven (Cancer Research UK Clinical Centre, UNITED KINGDOM),<br />

Robert Tonge, Jianhe Peng, Patricia Harnden, Peter Selby, Rosamonde Banks<br />

Identification Of Differentially Expressed Proteins In Acute Coronary Syndromes<br />

Veronica M. Darde (Immunology Department. Fundacion Jimenez Diaz / Proteomics<br />

Unit. Hospital Nacional de Paraplejicos. SESCAM, SPAIN), Maria G. Barderas, Fernando de<br />

la Cuesta, Julio J. Nacher, Lorenzo Lopez-Bescos, Jose Tunon, Jesus Egido, Fernando Vivanco<br />

P-MON-041<br />

P-MON-042<br />

P-mon-043<br />

P-MON-044<br />

P-MON-045<br />

P-MON-046<br />

P-MON-047<br />

P-MON-048<br />

Mrm Assay Development For Targeted Proteomics Of Genomics Candidates For<br />

Progression Of Crc<br />

Joerg Dojahn (Applied Biosystems Germany, GERMANY), Beatriz Carvalho, Jakob<br />

Albrethsen, Jaco C. Knol, Matthias Glückmann, Christof Lenz, Connie R. Jimenez,<br />

Gerrit A. Meijer<br />

SELDI-TOF-MS Meets BN-PAGE: Combining Protein Interaction Studies And<br />

Biomarker Discovery<br />

Niko Escher (Institute of Human Genetics and Anthropology, GERMANY), Robert Kob,<br />

Melle Christian, Ferdinand von Eggeling<br />

Comparative Proteomic Analysis Of Korean Native Cattle Muscle From Different<br />

Depots<br />

Jang Eun Jeong (National Institute of Animal Science, KOREA), Park Soo-Jin, Park<br />

Mi-Rim, Kwon Seulmina, Hong Sung-Gu, Kim Dong-Woon, Lee Hyun-Jeong<br />

Global Mapping Of Transcription Factor Expression Patterns<br />

Jeffrey Falk (Aviva Systems Biology, UNITED STATES), Lingxun Duan, Mingjie Jin,<br />

Dongyan Liu, Xiang Dong Fu<br />

A Quantitative Immunoaffinity Enrichment – LC/MS/MS Method For MMP9 From<br />

Mouse Serum<br />

Mireia Fernandez Ocana (Pfizer, UNITED KINGDOM), Hendrik Neubert, Phil Clarke,<br />

Mark Fidock<br />

Identification Of Colorectal Cancer Biomarkers From Mouse Colon Tumor Secretome<br />

Remond J.A. Fijneman (VU University Medical Center, Dept. of Medical Oncology /<br />

Dept. of Pathology, THE NETHERLANDS), Meike de Wit, Maral Pourghiasian, Sander<br />

Piersma, Pien M. van Diemen, Victor W.H. van Hinsbergh, Ron Smits, Riccardo<br />

Fodde, Gerrit A. Meijer, Connie R. Jimenez<br />

Biomarker Discovery In A Mouse Model Of Trait Anxiety<br />

Michaela Filiou (Laboratory of Proteomics and Biomarkers, GERMANY), YY Zhang, B Bisle,<br />

E Frank, MS Kessler, K Haegler, G Maccarrone, B Hambsch, R Landgraf, CW Turck<br />

Differential Protein Expression Analysis Of Endothelial Cells Treated With<br />

Growth Factors<br />

John Flensburg (GE Healthcare Bio-Sciences AB, SWEDEN), Mandana Fasth, Fuad<br />

Bahram, Lena Claesson-Welsh<br />

70 71


P-MON-049<br />

P-MON-050<br />

P-MON-051<br />

P-MON-052<br />

Separation Of Endogenuous Plasma Adiponectin Oligomers And Isoforms Using<br />

Free Flow Electrophoresis<br />

Aude Foucher (BD, UNITED STATES), Craig Gelfand<br />

Diagnostic Plasma Biomarkers Of Alcoholism In Non-Human Primates<br />

Willard M Freeman (Penn State College of Medicine, UNITED STATES), Pamela Noto,<br />

Heather VanGuilder, Kathleen Grant, Kent Vrana<br />

Withdrawn<br />

Proteomics And Molecular Markers In Cin2-3 Punch Biopsies And Normal<br />

Cervical Epithelium<br />

Ane Cecilie Munk, Cristina Furlan (Department of Pathology, Stavanger University<br />

Hospital, NORWAY), Ivar Skaland, Emiel Janssen, Cato Brede, Kjell Løvslett, Bent<br />

Fiane, Stein-Tore Nilsen, Jan P.A. Baak, Anne Bjørnstad<br />

P-MON-063<br />

P-MON-064<br />

P-MON-065<br />

Role Of Pkc¦Â In Hepatocellular Carcinoma Cells Migration And Invasion: A<br />

Potential Therapeutic Target<br />

Kun Guo (Liver Cancer Institute, Zhong shan Hospital, Fudan University / Research<br />

Center for Cancer, Institute of Biomedical Science, Fudan University, CHINA),<br />

Xiaonan Kang, Yan Li, Xuefei Li, Lu Sun, Yinkun Liu<br />

Quantitative Proteomic Analysis Of The Matrix Proteins From Human Dermal<br />

Fibroblasts<br />

Moon Kyung Ha (Department of Biochemistry and Molecular Biology, SOUTH KOREA),<br />

Haeri Choi, Young Hoon Son, Jiheon Rhim, Sung Chun Cho, Sang Chul Park<br />

A New Strategy For Plasma Protein Biomarker Discovery In Ovarian Cancer<br />

Ruth Hüttenhain (Institute of Molecular Systems Biology, ETH Zurich / Competence<br />

Center of Systems Physiology and Metabolic Diseases, ETH Zurich, SWITZERLAND),<br />

Daniela Dinulescu, Bruno Domon, Ruedi Aebersold<br />

P-MON-053<br />

P-MON-054<br />

P-MON-055<br />

P-MON-056<br />

Identification Of Differentially Expressed Genes Between Diabetes VS Healthy<br />

Srinubabu Gedela, Appa Rao Allam (Andhra University College of Engineering, INDIA)<br />

Proteomic Analysis Of Differentially Expressed Proteins In Swiss Mice Following<br />

Glyphosate Exposure<br />

Jasmine George (Indian Institute of Toxicolgy Research, INDIA), Preeti Roy,<br />

Yogeshwer Shukla<br />

Stratification And Monitoring Of Juvenile Arthritis Patients By Synovial<br />

Proteome Profile<br />

David Gibson (Arthritis Research Group, Queen’s University Belfast, UNITED KINGDOM),<br />

Sarah Blelock, Sorcha Finnegan, Caitriona Scaife, Stephen Pennington, Michael Dunn<br />

The Candida Immunome As A Mine For Clinical Biomarker Development For<br />

Invasive Candidiasis<br />

Aida Pitarch, César Nombela, Concha Gil (Department of Microbiology II, Faculty of<br />

Pharmacy, Complutense University of Madrid, SPAIN)<br />

P-MON-066<br />

P-MON-067<br />

P-MON-068<br />

P-MON-069<br />

Peptidome And Proteome Analyses Of Lymph Nodes In A Mouse Model Of<br />

Chemical-Induced Asthma<br />

Steven Haenen (K.U. Leuven, BELGIUM), Elke Clynen, Jeroen Vanoirbeek, Peter Hoet,<br />

Liliane Schoofs<br />

Absolute Quantitation Of Endogenous Peptides Using High Resolution Selected<br />

Reaction Monitoring<br />

Reiko Kiyonami, Rosa Viner, Vlad Zabrouskov, Akraporn Prakobphol, H. Ewa Witkowski,<br />

Steven C. Hall, Susan J. Fisher, Markus Hardt (Thermo Fisher Scientific, UNITED STATES)<br />

Proteomics And Subproteomics In The Quest For New Diagnostic Leads In Human<br />

Disease<br />

Niels H.H. Heegaard (Statens Serum Institut, DENMARK)<br />

Promising Tool For Diagnostic Evaluation Of Hepatitis Induced Fibrogenesis<br />

Corinna Henkel (Institute of Pathology, RWTH University Hospital Aachen, GERMANY),<br />

Kristina Schwamborn, Olav Gressner, Margarete Odenthal, Ruth Knuechel, Ralf Weiskirchen<br />

P-MON-057<br />

P-MON-058<br />

P-MON-059<br />

P-MON-060<br />

P-MON-061<br />

P-MON-062<br />

Identification Of Parkinson’s Disease Markers By Systematic Screening Of<br />

Protein Arrays<br />

Heike Goehler (Medizinisches Proteom-Center, Ruhr-University Bochum, GERMANY),<br />

Axel Kowald, Angelika Lueking, Christian Scheer, Florian Tribl, Manfred Gerlach,<br />

Peter Riederer, Katrin Marcus, Helmut E. Meyer<br />

Withdrawn<br />

Proteomic Analysis Of Urine From Patients With Urologic Chronic Pelvic Pain<br />

Syndromes<br />

Young Ah Goo (University of Washington, UNITED STATES), Clair Yang, Priska von<br />

Haller, Alvin Liu, David Goodlett<br />

The Evolution Of Tissue Markers Analyzed By Maldi-Ms Imaging<br />

Richard Goodwin (Institute of Biomedical and Life Sciences, University of Glasgow,<br />

UNITED KINGDOM), Stuart Cobb, Andrew Pitt<br />

Identification Of Protein Biomarker For Schizophrenia In The Postmortem<br />

Prefrontal Cortex Using 2D Electrophoresis Analysis<br />

Maria Jose Guerrero (Proteomika S.L, SPAIN), Marcel Ferrer-Alcón, Laureano<br />

Simón, Antonio Martinez, Jose Javier Meana<br />

Investigation Of The Serum Proteome To Look For Ionizing Radiation Biomarkers<br />

Olivier Guipaud (Institut de Radioprotection et de Sûreté Nucléaire, FRANCE), Marie<br />

Thézénas, Valérie Holler, Joëlle Vinh, Marc Benderitter<br />

P-MON-070<br />

P-MON-071<br />

P-MON-072<br />

P-MON-073<br />

P-MON-074<br />

P-MON-075<br />

Validation Of High Throughput Protein Biomarker Assays<br />

Nicholas B. Herold (Quadraspec, Inc., UNITED STATES), Fred E. Regnier, Chad W. Barden<br />

Targeted Proteomics Of Transcription Factors In Breast Cancer And Embryonic<br />

Stem Cells<br />

Johannes Hewel (Terrence Donnelly Centre for Cellular and Biomolecular Research,<br />

University of Toronto, CANADA), Charanjit Sandhu, Kento Onishi, Peter Zandstra,<br />

Andrew Emili<br />

Multi-Institutional Validation Of Plasma Biomarker Of Pancreatic Cancer By<br />

MALDI-TOF-MS<br />

Kazufumi Honda (Cancer Proteomics Project National Cancer Center Research<br />

Institute, JAPAN), Masaya Ono, Tesshi Yamada<br />

Withdrawn<br />

Mining The Serum Proteome For Cervical Cancer Biomarkers<br />

Péter Horvatovich (University of Groningen, THE NETHERLANDS), Natalia<br />

Govorukhina, Iwona Sobczak-Elbourn, Krisztina Páal, Frank Suits, Peicheng Du,<br />

Christin Christin, Berend Hoekman, Ate van der Zee, Rainer Bischoff<br />

A Search For Biomarkers Of Type 1-Diabetes By Lc-Esi-Itraq And Label Free<br />

Lc-Maldi Serum Proteomics<br />

Waltteri Hosia (Turku Centre for Biotechnology, FINLAND), Robert Moulder, Heidi<br />

Vähämaa, Jussi Salmi, Tero Aittokallio, Mikko Katajamaa, Olli Simell, Olli Nevalainen,<br />

Riitta Lahesmaa, et.al.<br />

72 73


P-MON-076<br />

Identification And Evaluation Potential Biomarkers Of Human Glioblastoma Multiforme<br />

Chiungyin Huang (Chang-Gung Memorial Hospital, TAIWAN), Li-Ying Feng, Jyh-Wei Shin,<br />

Kuo-Chen Wei<br />

P-MON-089<br />

Proteomic Analyses Of Microbial Activity In The Human Gut – The Beginning<br />

Carolin Kolmeder (Department of Basic Veterinary Sciences, University of Helsinki,<br />

FINLAND), Anne Salonen, Airi Palva, Willem M. de Vos<br />

P-MON-077<br />

A Novel System For Efficiently Screening Tumor-Related Proteins Using Antibody<br />

Proteomics<br />

Sunao Imai (NiBio / Osaka University, JAPAN), Shin-ichi Tsunoda, Yasunobu Yoshida,<br />

Shinsaku Nakagawa, Junya Fukuoka, Yasuo Tsutsumi<br />

P-MON-090<br />

Apc-Binding Protein EB1 Is Novel Prognostic Biomarker In Hepatocellular Carcinoma<br />

Tatsuya Orimo, Hidenori Ojima, Nobuyoshi Hiraoka, Shigeru Saito, Satoru Todo,<br />

Setsuo Hirohashi, Tadashi Kondo (Proteome Bioinformatics Project, National Cancer<br />

Center Research Institute, JAPAN)<br />

P-MON-078<br />

P-MON-079<br />

P-MON-080<br />

P-MON-081<br />

P-MON-082<br />

P-mon-083<br />

Characterization Of Inflammatory/Oxidative Stress Protein Modifications<br />

Jon Jacobs (Pacific Northwest National Laboratory, UNITED STATES), Weijun Qian,<br />

Diana Bigelow, Collette Sacksteder, Richard Corley, Joel Pounds<br />

Proteome Analysis For Identification And Validation Of Potential Biomarkers In<br />

Colorectal Cancer<br />

Lucy Jankova (ANZAC Research Institute, AUSTRALIA)<br />

Protein Profiles Differentiating Triple Negative Breast Cancer From Er/Pgr<br />

Expressing Breast Cancer<br />

Eun-Mi Jeong (Cancer Research Institute, Seoul National University College of Medicine,<br />

KOREA), Jong Won Lee, Wonshik Han, Ji-Yeon Bae, Jae Kyo Yi, Dong Hyun Kim,<br />

Cheolju Lee, Myeong-Hee Yu, Dong-Young Noh<br />

Parallel Analysis Of Proteomic And Metabolic Profiles On Nonalcoholic Fatty<br />

Liver Disease<br />

Ying Jiang (State Key Laboratory of Proteomics, Beijing Proteome Research Center,<br />

Beijing Institute of Radiation Medicine, CHINA), Hao Li, Lan Wang, Youming Li, Fuchu He<br />

Antibody Pattern And Retinal Ganglion Cell Loss In A Heat Shock Protein<br />

Immunization Animal Model<br />

Stephanie Joachim (Experimental Ophthalmology, GERMANY), Martin Wax, Norbert<br />

Pfeiffer, Franz Grus<br />

Proteomic Anaysis Of Differentially Expressed Proteins In Colorectal Cancer<br />

Kee Kang (Deaprtment of Biochemistry, Gyeongsang National University School of<br />

Medicine, KOREA), Jung-Hun Kang, Young-Tae Joo, Eun-Jung Jung, Gyeong-Won Lee,<br />

Hoon-Gu Kim, Hee Cho, Bok Cho, Sang-Kyung Choi<br />

P-MON-091<br />

P-MON-092<br />

P-MON-093<br />

P-MON-094<br />

P-MON-095<br />

IsoAsp7-containing Beta-Amyloid As A Potential Biomarker Of Alzheimer’s Disease<br />

Philipp Tsvetkov, Igor Popov, Eugene Nikolaev, Alexander Archakov, Alexander Makarov,<br />

Sergey Kozin (Orekhovich Institute of Biomedical Chemistry, Russian Academy of<br />

Medical Science, RUSSIAN FEDERATION)<br />

Guided Interpretation Of Clinical Proteome Profiling In Acute Myocardial Infarction<br />

Markus Kubicek (Department of Medical and Chemical Laboratory Diagnostics,<br />

Medical University of Vienna, AUSTRIA), Klaus Distelmaier, Rene Stempfer, Daniela<br />

Dunkler, Susanne Winkler, Johannes Jakowitsch, Helge Wimmer, Christopher Gerner,<br />

Irene Lang, Oswald Wagner<br />

Ovarian Cancer Ascites Fluid Subproteome: Home Of Potential Biomarkers For<br />

Ovarian Cancer<br />

Cynthia Kuk (Department of Laboratory Medicine and Pathobiology, University of<br />

Toronto / Department of Pathology and Laboratory Medicine, Mount Sinai Hospital,<br />

CANADA), Antoninus Soosaipillai, Vathany Kulasingam, Chris R. Smith, Ihor Batruch,<br />

Eleftherios P. Diamandis<br />

Spermatozoa Fertility Biomarkers Display by Intact Cells MALDI-TOF Mass Spectrometry<br />

Valérie Labas (INRA, Plate-forme de Protéomique Analytique et Fonctionnelle –<br />

Laboratoire de Spectrométrie de Masse, FRANCE), Clémence Belleannee, Maya<br />

Belghazi, Françoise Dacheux, Jean-Louis Dacheux<br />

Biomarker Discovery By MRM – Combining Sensitivity With Throughput<br />

Vinzenz Lange (Competence Center for Systems Physiology and Metabolic Diseases<br />

/ Institute for Molecular Systems Biology, ETH Zürich, SWITZERLAND), Carsten<br />

Danzer, Alexander Schmidt, Katrin Eckhardt, Reto Ossola, Bruno Domon, Wilhelm<br />

Krek, Ruedi Aebersold<br />

P-MON-084<br />

P-MON-085<br />

P-MON-086<br />

P-MON-087<br />

Reduced Level Of Peroxiredoxin Proteins In Cancer Determined Using Stable<br />

Isotope Labeled Quantitative Plasma Analysis<br />

Hiroyuki Katayama (Fred Hutchinson Cancer Research Center, JAPAN), Vitor Faca,<br />

Sandra Faca, Sharon Pitteri, Ji Qiu, Hong Wang, Alexei Krasnoselesky, Lisa Newcomb,<br />

Qing Zhang, Sam Hanash<br />

Disease-Specific Serum Peptides In Patients With Systemic Sclerosis<br />

Ynag Xiang, Toshihiro Matsui, Mitsumi Arito, Naoya Suematsu, Kazuo Yudoh,<br />

Tomohiro Kato (Clinical Proteomics and Molecular Medicine, St. Marianna University<br />

Graduate School of Medicine, JAPAN)<br />

The ‘Blood Donor Biobank’: An Innovative Resource For Biomarker Research<br />

Claudia Kellner (Blutspendedienst des Bayerischen Roten Kreuzes gGmbH, GERMANY)<br />

Proteomic Analysis Identifies S100A8 And S100A9 As Serological Markers For<br />

Colorectal Cancer<br />

Hye-Jung Kim (Life Sciences Division, Korea Institute of Science and Technology /<br />

Department of Biochemistry, College of Science, Yonsei University, KOREA), Hyun Ju<br />

Kang, Seung-Taek Lee, Myeong-Hee Yu, Hoguen Kim, Cheolju Lee<br />

P-MON-096<br />

P-MON-097<br />

P-MON-098<br />

P-MON-099<br />

Analysis Of Serum Glycoproteins Relevant To Breast Cancer By An Indirect<br />

Approach Using Hs578T Cells<br />

Younghee Ahn, Un-Beom Kang, Myeong-Hee Yu, Cheolju Lee (Life Sciences Division,<br />

Korea Institute of Science and Technology, KOREA)<br />

Selection And Validation Of Liver Cancer Biomarker Candidates From Human<br />

Plasma Proteome<br />

Ju Yeon Lee (Korean Basic Science Institute, KOREA)<br />

Identification Of Inadequately Expressed Proteins In Plasma Of Recurrent<br />

Spontaneous Abortion (RSA) Patients<br />

Min-Young Lee (Graduate School of Life Science and Biotechnology, Pochon CHA<br />

University, CHA General Hospital, KOREA), Myung-Sun Kim, Bon-Hee Gu, Jong-Ho<br />

Choi, Sangjin Song, Bum-Chae Choi, Kwang-Hyun Baek<br />

Proteomic Analysis In The Substantia Nigra Of The Mouse Exposed To The Paraquat<br />

Sujin Lee (School of Life Sciences & Biotechnology, College Of Natural Sciences,<br />

Kyungpook National University, KOREA), Sun-Mi Yun, Hyun Tae Kim, Ung-Kyu Choi,<br />

Nam Sik Eum, Gui-hyang Choi, Song Cui, Tae-Cheon Kang, Soo Young Choi, Oh-Shin Kwon<br />

P-MON-088<br />

Identification Of PGK1 As Biomarker For Oxidative Stress<br />

Jong Sang Kim (Kyungpook National University, School of Life and Food Sciences,<br />

KOREA), Chan Ho Jang, In Ae Lee, Lesley Quintos, Mi Kyung Sung, Sung Joon Lee<br />

P-MON-100<br />

Proteome Profiling Of Primary Mammary Epithelial Cells Derived From MMTVneu<br />

Mice<br />

Taehoon Lee (Sigmol Inc., THE NETHERLANDS), Incheol Shin, Sungwoo Park, Dong Young Noh<br />

74 75


P-MON-101<br />

Proteomic Profiling For Candidate Biomarkers Of Breast Cancer Response To<br />

Chemotherapy<br />

Sharon Leong (Kolling Institute of Medical Research, The University of Sydney,<br />

AUSTRALIA), Samath Pen, Richard Christopherson, Robert Baxter<br />

P-MON-114<br />

Proteomics Analysis Of Isolated Membrane Fractions From Normal And<br />

Cancerous Breast Cell Lines<br />

Priyanka Maurya (National Institute for Cellular Biotechnology, IRELAND), Michael<br />

Henry, Martin Clynes, Paula Mealedy<br />

P-MON-102<br />

P-MON-103<br />

P-MON-104<br />

P-MON-105<br />

P-MON-106<br />

P-MON-107<br />

P-MON-108<br />

P-MON-109<br />

Withdrawn<br />

Quantitative, Top-Down Identification Of Differentially Expressed, Endogenous<br />

Peptides In Maternal Serum<br />

Mary F Lopez, David Sarracino (ThermoFisher Scientific BRIMS, UNITED STATES),<br />

Bryan Krastins, Kypros Nicolaides, Michael Athanas, Amol Prakash<br />

Discovery Of Mechanistic Biomarkers With A Causal Network Model Of Gefitinib<br />

In Cancer<br />

Joseph Loureiro (Genstruct, Inc., UNITED STATES), Gil Blander, Ben Wong, Ailan Guo,<br />

Dave Merberg, Christian Reich, Michael Comb, Keith Elliston<br />

Proteomic Analysis Of Circulating Immune Complexes Reveals Disease-Associated<br />

Proteins<br />

Jason Low (Saint Louis University School of Medicine, UNITED STATES), Anil Chauhan,<br />

David Gibson, Mengmeng Zhu, Sixue Chen, Madeleine Rooney, Terry Moore<br />

Identification Of Significantly Differentially Expressed Peptides In Pre-Eclamptic<br />

Tissue<br />

Theo M. Luider (Dept. of Neurology, Erasmus Medical Center, THE NETHERLANDS),<br />

Coskun Guzel, Christianne JM de Groot, Eric A.P. Steegers<br />

Diagnostic Information Of Serum Protein Profiling Independent Of CA125 In<br />

Ovarian Tumors<br />

Anne Kjaergaard Callesen, Jonna Skov Madsen (Department of Clinical Biochemistry,<br />

Vejle County Hospital, DENMARK)<br />

Proteomic Screen Identifies A Panel Of Proteins Indicative Of Response To Gefitinib<br />

Parag Mallick (Cedars-Sinai Medical Center / UCLA, UNITED STATES)<br />

Proteomic Profiling Of Retinoblastoma: A Preliminary Study<br />

K Mallikarjuna (Vision Research Foundation, Sankara Nethralaya, INDIA), S Krishnakumar,<br />

J Biswas, PR Deepa, V Khetan, T Sharma, L Gopal, CS Sundaram, Y Sharma<br />

P-MON-115<br />

P-MON-116<br />

P-MON-117<br />

P-MON-118<br />

P-MON-1<strong>19</strong><br />

P-MON-120<br />

The Development Of An Mrm Assay For Quantitation Of Low Abundance<br />

Cytochrome P450 Proteins<br />

Therese McKenna (Waters Corporation MS Technologies Centre, UNITED KINGDOM),<br />

Amy Bartlett, Christopher Hughes, Johannes Vissers, Scott Geromanos, Catalin<br />

Donneanu, James Langridge<br />

Bronchoalveolar Lavage Fluid Proteomics Patterns In Sulfur Mustard Exposed<br />

Patients<br />

Hossein Mehrani (Baqiyatallah University of Medical Sciences, IRAN), Mostafa Ghanei,<br />

Jafar Aslani, Leila Golmanesh<br />

A Label Free Quantitative Proteomic Strategy And Its Application In Biomarker<br />

Discovery Based On LC-ESI-MS/MS<br />

Chen Ming (Tianjing Institute of Hygiene and Environmental Medicine /Beijing Proteome<br />

Research Center, CHINA), Ying Wantao, Qian Lingjia, Qian Xiaohong<br />

Bioinformatics For Proteomic Analyses Applied To Metastatic Disease In<br />

Prostate Cancer<br />

Alberto Molares Vila (Department of Analytical Chemistry, Chemistry Faculty, University<br />

of Vigo / Biomedical Foundation of Vigo University Hospital, SPAIN), Alejandro Gómez<br />

Pinillos, Gonzalo Gómez López, María del Val Toledo Lobo, Juan Oses Prieto, Antonio<br />

Ojea Calvo, Enrique Caso Peláez, Ana Gago Martínez<br />

Determination Of Biomarkers Of Skin Disease By MALDI-MS And MALDI-MSI In<br />

Vitro Skin Models<br />

Tasneem Muharib (Biomedical Research Centre, UNITED KINGDOM), Vikki Carolan,<br />

Duncan Rimmer, John White, Malcolm Clench<br />

Using Different Proteomics Techniques To Identify Glioma- Neovascularisation-<br />

Related Proteins<br />

Dana Mustafa (Erasmus MC, Pathology department, THE NETHERLANDS), Peter<br />

Burgers, Lennard Dekker, Rober-Jan Lamers, Halima Charif, Mark Titular, Peter<br />

Sillevis Smith, Theo Luider, Johan Kros<br />

P-MON-110<br />

P-MON-111<br />

Cleft Palate Regulated Salivary Proteins<br />

Reka Tihanyi (Institute of Biochemistry and Medical Chemistry, Medical School,<br />

University of Pecs, HUNGARY), Tamas Gyula Szabo, Gyula Szabo, Viktoria Nemeth,<br />

Alexandra Vaczy, Balazs Sumegi, Laszlo Mark<br />

Development Of Instrument Parameters For Maximum Product Ion Formation In<br />

MRM MS<br />

Daniel Martin (Institute for Systems Biology, UNITED STATES), Ashley Eastham,<br />

Amelia Peterson, Li Huang<br />

P-MON-121<br />

P-MON-122<br />

Identification And Characterization Of YPRC-G1, An N-Linked Glycoprotein And<br />

Putative Biomarker For Hepatocellular Carcinoma<br />

Keun Na (Yonsei Proteome Research Center, Department of Biochemistry, Yonsei<br />

University, KOREA), Eun-Young Lee, Hyoung-Joo Lee, An-Sung Jeong, Kwang-Youl Kim,<br />

Min-Seok Kwon, Hanna Lee, Sang-Yon Cho, Hoguen Kim, Young-Ki Paik<br />

Comparison Of Different Immunoaffinity Columns To Remove High Abundant<br />

Proteins From Follicular Fluid Of Different Species<br />

Somayyeh Nadaf (INRA, FRANCE)<br />

P-MON-112<br />

P-MON-113<br />

Proteome Analysis Of Schizophrenia Brain Tissue<br />

Daniel Martins de Souza (Max-Planck-Institut für Psychiatrie and Laboratório de<br />

Neurociências, GERMANY / Instituto de Psiquiatria – Faculdade de Medicina da USP,<br />

BRAZIL) Giuseppina Maccarrone, Wagner F. Gattaz, Andrea Schmitt, Emmanuel<br />

Dias-Neto, Chris W. Turck<br />

Prostate Cancer Biomarkers To Predict Response To Immunotherapy<br />

Balwir Matharoo-Ball (The John Van Geest Cancer Research Centre, UNITED KINGDOM),<br />

Christophe Lemetre, Vicky Adams, Else-Marit Inderberg Suso, Stephen Ward,<br />

Gustav Gaudernack, Graham Ball, Robert Rees<br />

P-MON-123<br />

P-MON-124<br />

Methods For High-Throughput Analysis Of The Urinary Proteome<br />

Nagarjuna Nagaraj (MPI Biochemie, GERMANY), Alexandre Zougman, Juergen Cox,<br />

Matthias Mann<br />

MS Approaches To Address The Role Of An Amyloid-B In Alzheimer’s Plague<br />

Formation Onset<br />

Evgeny Nikolaev (The Institute for Energy Problems of Chemical Physics / Orekhovich<br />

Institute of Biomedical Chemistry / Emanuel Institute of Biochemical Physics, Russian<br />

Academy of Science, RUSSIA), Igor Popov, Sergey Kozin, Elena Kugaevskaya,<br />

Alexander Archakov, Alexey Kononikhin<br />

76 77


P-MON-125<br />

P-MON-126<br />

Pharmaco-Proteomics At The Clinical Blood – Brain Junction<br />

MingMing Ning (Clinical Proteomics Research Center, Dept of Neurology, Mass<br />

General Hospital/Harvard Medical School, UNITED STATES), Ferdinando Buonanno,<br />

Dave Sarracino, Mary Lopez, Dayse Sena, Diana Walleigh, Xiaoying Wang, David McMullin,<br />

Eng H. Lo<br />

Identifying Candidate Biomarkers Of Exposure To The Mycotoxin Deoxynivalenol<br />

Using Proteomics<br />

Andre Nogueira da Costa (Molecular Epidemiology Unit, Centre for Epidemiology and<br />

Biostatistics, LIGHT Laboratories, UNITED KINGDOM), Renée S. Mijal, Jeff Keen,<br />

John Findlay, Christopher P. Wild<br />

Innovation In Peptide & Protein Seperation Technologies<br />

P-MON-127<br />

P-MON-128<br />

P-MON-129<br />

P-MON-130<br />

Isolation Of Protein Isoforms By Free Flow Electrophoresis Preserving Biological<br />

Activity<br />

Afsaneh Abdolzade-Bavil (Becton Dickinson GmbH, Planegg, GERMANY), Christian<br />

Obermaier, Siegfried Hirler, Mikkel Nissum, Christoph Dufter, Gerhard Weber,<br />

Christoph Eckerskorn<br />

A Simple Way To Use A 1D Split-Free Nano-HPLC In An Automated 2D LC-MS/MS<br />

SETUP<br />

Michael Andersen (Proxeon Biosystems A/S, DENMARK), Paul Taylor, Mike Moran,<br />

Alexandre Podtelejnikov, Ole Vorm, Thomas Kislinger<br />

New Stain Free Gel System - Compatibility With Western Blotting And Ms Based<br />

Protein Identification<br />

Kumar Bala (Bio-Rad Laboratories, UNITED STATES)<br />

Proteomics Based On Peptide Fractionation By SDS-Free Page<br />

Vladimir Besada (Center for Genetic Engineering and Biotechnology, CUBA), Yassel<br />

Ramos, Elain Gutierrez, Yoan Machado, Aniel Sánchez, Lila Castellanos-Serra,<br />

Luis Javier González, Jorge Fernández-de-Cossio, Yasset Pérez-Riverol, Lázaro<br />

Betancourt, Jeovanis Gil, Gabriel Padrón<br />

P-MON-137<br />

P-MON-138<br />

P-MON-139<br />

P-MON-140<br />

P-MON-141<br />

P-MON-142<br />

P-MON-143<br />

P-MON-144<br />

A Multi-Approach Experiment To Analyse Aphid Salivary Proteome<br />

Frederic Francis (Gembloux Agricultural University, Functional & Evolutionary<br />

Entomology, BELGIUM), Nicolas Harmel, Eric Haubruge, Edwin de Pauw<br />

Ultrasonic Assisted Protein Enzymatic Digestion Applied To Gel-Separated<br />

Proteins<br />

Marco Galesio (Requinte, Universidade Nova de Lisboa, PORTUGAL), Diana Vieira,<br />

Raquel Rial, Jose Capelo<br />

Analysis Of Active Proteins Extracted From Deer Antler By 2D-SEC-IEC<br />

Liang Gao (Dalian Institute of Chemical Physics, Chinese Academy of Sciences,<br />

CHINA), Zhen Liang, Lihua Zhang, Yushu Huo, Yukui Zhang<br />

Detection-Identification Of Trace Protein Impurities Using Combinatorial Peptide<br />

Libraries<br />

Luc Guerrier (Bio-Rad Laboratories C/o CEA-Saclay, FRANCE), Egisto Boschetti,<br />

Frederic Fortis, Pier-Giorgio Righetti<br />

Phosphopeptides: Coupling Of Immunoaffinity And TIO2 Metal Affinity<br />

Francois Guillonneau (Plateforme Proteomique Université Paris Descartes,<br />

FRANCE), Lamya Haddaoui, Patrick Mayeux, Claude Netter, Luc Camoin<br />

Separation Of Membrane Proteins And Protein Complexes Using Free-Flow<br />

Electrophoresis<br />

Kristina Hartmann (BD Diagnostics, Innovation Center Biotechnology, GERMANY),<br />

Sabine Kronbauer, Markus Islinger, Christoph Eckerskorn, Mikkel Nissum<br />

Utilization Of Immunoaffinity Interaction For Specific Antibody And Peptide Separation<br />

MD Hasan (Dalhousie University, Department of Process Engineering and Applied<br />

Science, CANADA), Yoichi Kumada, Shigeo Katoh<br />

Solid Phase Extraction - Liquid Chromatography (SPE-lc) Interface For<br />

Automated Peptide Separation And Identification By Tandem Mass Spectrometry<br />

Ole Bjeld Hørning (Proxeon A/S, DENMARK), Michael Barrett Andersen, Ole Vorm,<br />

Ole Nørregaard Jensen<br />

P-MON-131<br />

P-MON-132<br />

P-MON-133<br />

External Gradient Chromatofocusing For Quantitative Analysis Of Mammalian Lysates<br />

Karl Burgess (University of Glasgow, UNITED KINGDOM), Kit-Yee Tan, Lachislav<br />

Tsonev, Terry Sheehan, Ken Cook, Andrew Pitt<br />

Devil In IEF: Using Electric Conductivity To Monitor Salt Concentration Of 2-DE Samples<br />

Tzi-Ning Chen, Szu-Yu Wu, Ching-Yu Lin, Han-Min Chen (Department of Life-Science /<br />

Institutes of Applied Science and Engineering, Catholic Fu-Jen University, TAIWAN)<br />

Isoelectric Western Blotting (iWB) After Digital Proteome Chip (dPC) Focusing<br />

Thomas Miller, James Dasch (Protein Forest, UNITED STATES), Malcolm Pluskal,<br />

Russell Garlick, Stephen Haralampu, Bill Skea, Bhanu Singh, Dave Malarkey, Sun Tam<br />

P-MON-145<br />

P-MON-146<br />

2D Protein And Peptide Separation Of Serum By Preparative Monolithic<br />

Chromatography<br />

Linda IJsselstijn (Erasmus Medical Center, Department of Neurology, THE NETHERLANDS),<br />

Deborah Kronenberg, Remco Swart, Peter Koudstaal, Peter Sillevis Smitt, Monique<br />

Breteler, Theo Luider<br />

MSRAT, A Proteomic Sample Software Analysis Tool<br />

Oren Kagan, James Dasch, Russell Garlick, Bill Skea, Andrew Johnson (Protein Forest,<br />

Inc., UNITED STATES), Yakov Chudnovsky, David Sabatini, Eric Spooner, William Hahn,<br />

Milan Chheda<br />

P-MON-134<br />

P-MON-135<br />

P-MON-136<br />

Fast Targeted Proteomics On A Chip<br />

Zuzana Demianova (Protein Chemistry Unit, Institute of Biomedicine, University of<br />

Helsinki, FINLAND), Sami Franssila, Marc Baumann<br />

An Evaluation Of The Suitability Of 1.9 Um Particle Packed Columns For<br />

Proteomics Applications<br />

Monica Dolci, Charlotte Blythe, Dafydd Milton (Thermo Fisher Scientific, UNITED KINGDOM)<br />

Seppro® Fractionation Platform For Enhanced Detection Of Biomarkers In Biofluids<br />

Xiangming Fang (GenWay Biotech, Inc., UNITED STATES), Lei Huang, Weijun Qian,<br />

Sergey Sikora, Kimimichi Obata, Richard Smith, Wei-Wei Zhang<br />

P-MON-147<br />

P-MON-148<br />

P-MON-149<br />

Proteome Wide Analysis Of Protein Syntesis And -Breakdown In E.Coli<br />

Gertjan Kramer (University of Amsterdam, THE NETHERLANDS), Merel Nessen,<br />

Richard Sprenger, JaapWillem Back, Leo de Koning, Jan van Maarseveen, Joost<br />

Teixeira de Mattos, Klaas Hellingwerf, Luitzen de Jong, Chris de Koster<br />

SDR HyperD Resin For Detergent Removal Prior To Mass Spectrometry Analysis<br />

Hongshan Li (Pall Corporation, UNITED STATES), Saurabh Nagpal, Gurpreet Nagpal,<br />

Brian Miller, Lisa Bradbury<br />

Microchip-Based Monolithic Immobilized PH Gradient Isoelectric Focusing For<br />

Protein Analysis<br />

Yu Liang (Dalian Institute of Chemical Physics, CHINA), Yongzheng Cong, Zhen Liang,<br />

Lihua Zhang, Yukui Zhang<br />

78 79


P-MON-150<br />

P-MON-151<br />

P-MON-152<br />

P-MON-153<br />

Depletion Of High Abundance Proteins In Serum By Protein Imprinted Polymers<br />

Jinxiang Liu (National Chromatographic R. &. A. Center, Dalian Institute of Chemical<br />

Physics, CHINA)<br />

Vascular Wall Profiling Adressess Deep Proteome From Minute Samples.<br />

Sebastian Mas (Universidad Autonoma Madrid, SPAIN), Roxana Martínez-Pinna,<br />

Fernando Vivanco, Jesús Egido<br />

Simple Proteomic Complexity Reduction Strategy For Human Plasma Combines<br />

Albumin & LgG Removal With Rapid Anion Exchange Fractionation<br />

Selladurai Masilamani (Pall India Pvt Ltd, INDIA)<br />

Protein Quantification And Separation Before 2D Electrophoresis Using LFII<br />

Judit Nagy (Imperial College, UNITED KINGDOM), Fiona Pereira, Stuart Hassard, Tony Cass<br />

P-MON-163<br />

P-MON-164<br />

P-MON-165<br />

Proteomics On A Chip For Monitoring Autoimmune Diseases<br />

Richard Schasfoort (University of Twente, THE NETHERLANDS), Bianca Beusink,<br />

Dietrich Kohlheyer, Angelique Lokate, Ger Pruijn, Ad de Jong, Linda Silvertand,<br />

Natasja Carol-Visser, Albert Heck, Albert van den Berg<br />

Use Of A Novel Hydrophilic-PVDF Membrane For The Immunodetection Of<br />

Phosphorylated Proteins Separated By Gel Electrophoresis<br />

Jun Park (Millipore, UNITED STATES), Masaharu Mabuchi, Ajay Sharma<br />

Observing Rapid H/D Exchange Of The Reactive Hydrogen On The Protein<br />

Molecules By Electrospray-Assisted Laser Desorption Ionization (ELDI) Mass<br />

Spectrometry<br />

Jentaie Shiea, Jingyueh Jeng (Department of Biotechnology, Chia Nan University of<br />

Pharmacy and Science, TAIWAN), Li-Hua Lo, Yi-Tzu Cho, Cheng-Hui Yuan<br />

P-MON-154<br />

Profiling Of Low Molecular Weight Human Plasma Proteins<br />

Myung Hee Nam (Korea Basic Science Institute, KOREA), DongGuen Sul, Jong Bok Seo,<br />

Jin Hee Lee, Sohee Phark, Kun Cho<br />

P-MON-166<br />

Top-Down Proteomics Analysis Using Automated 2D LC And Fractionation<br />

Evert-Jan Sneekes (Dionex Corporation Amsterdam, THE NETHERLANDS), Bas<br />

Dolman, Remco Swart<br />

P-MON-155<br />

P-MON-156<br />

P-MON-157<br />

P-MON-158<br />

Selective Purification Of Azide-Containing Peptides From Complex Mixtures<br />

Merel A. Nessen (Mass Spectrometry of Biomacromolecules - Swammerdam<br />

Institute of Life Sciences (SILS)/ Biomolecular Synthesis - Van ´t Hoff Institute<br />

for Molecular Sciences (HIMS), University of Amsterdam, THE NETHERLANDS),<br />

JaapWillem Back, Jan H. van Maarseveen, Gertjan Kramer, Leo J. de Koning, Luitzen<br />

de Jong, Henk Hiemstra, Chris G. de Koster<br />

Processing Samples for High-Throughput Clinical Mass Spec Using Parallel<br />

Electrophoresis<br />

Jeremy L. Norris (Protein Discovery, Inc., UNITED STATES), James A. Mobley, Greg<br />

Bowersock, James B. Harkins, Benjamin B. Katz<br />

Reduction Of High Abundance Proteins In Serum, Plasma And Non-Blood Samples<br />

With Proteominer Beads<br />

Aran Paulus (Bio-Rad Laboratories, UNITED STATES), Tim Wehr, Ning Liu, Katrina<br />

Academia, Steve Freeby, Egisto Boschetti<br />

The Secretome Of H460 Non Small Cell Lung Cancer Cells: Comparing Workflows<br />

Sander Piersma (oncoproteomics laboratory / VU medical center medical oncology,<br />

THE NETHERLANDS), Simone Span, Frank Kruyt, Remond Fijneman, Connie Jimenez<br />

P-MON-167<br />

P-MON-168<br />

P-MON-169<br />

P-MON-170<br />

Optimization Of Separation Power In One-Dimensional LC In Analysis Of<br />

Proteomics Samples<br />

Bas Dolman (Dionex Corporation Amsterdam, THE NETHERLANDS), Evert-Jan Sneekes,<br />

Sebastiaan Eeltink, Remco Swart<br />

Study Of Beta-Catenin-Associated Complex By Nanoprobe-Based Affinity Mass<br />

Spectrometry<br />

An-Kai Su (Institute of Chemistry, Academia Sinica, TAIWAN), Hsin-Huang Huang,<br />

Po-Chiao Lin, Chun-Cheng Lin, Jeou-Yuan Chen, Yu-Ju Chen<br />

A Facile Buffer Exchange Interface For On-Line Hyphenation With Trypsin<br />

Microreactor<br />

Liangliang Sun (National Chromatographic Research and Analysis Center, Dalian<br />

Institute of Chemical Physics / Graduate School of Chinese Academy of Sciences, CHINA),<br />

Xiaoqiang Qiao, Dingyin Tao, Zhen Liang, Weibing Zhang, Lihua Zhang, Yukui Zhang<br />

Protein Fractioned By Microscale Solution Isoelectric Focusing And<br />

Identification By HPLC-MS/MS<br />

Dingyin Tao (Chinese Academy of Science, CHINA), Jicheng Duan, Zhen Liang, Weibing<br />

Zhang, Lihua Zhang, Yukui Zhang<br />

P-MON-159<br />

Alternative Two Dimensional Electrophoresis – Offgel Electrophoresis Combined<br />

With High Sensitivity Microfluidic On-Chip Protein Detection<br />

Tobias Preckel (Agilent Technologies R&D and Mktg. GmbH & Co.KG, GERMANY),<br />

Andreas Ruefer, Christian Wenz, Martin Greiner<br />

P-MON-171<br />

An Alternative 2D-LC-Separation Scheme For Shotgun Proteomics Coupled To<br />

ESI Or MALDI MS/MS<br />

Andreas Tholey (Saarland University, Technische Biochemie, GERMANY), Maria Lasaosa,<br />

Nathanael Delmotte, Katja Melchior, Thomas Jakoby, Elmar Heinzle, Christian Huber<br />

P-MON-160<br />

P-MON-161<br />

P-MON-162<br />

Fast And Versatile : Fluroescent Staining Of Protein In Gels With<br />

Oxacarbocyanines<br />

Mireille Chevallet (CEA / iRTSV/ LBBSI, FRANCE), Hélène Diemer, Alain van<br />

Dorsselaer, Thierry Rabilloud<br />

Highly Efficient Depletion Strategy Improves Erythrocyte Proteome Coverage<br />

Dramatically<br />

Jeffrey Ringrose (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />

University, THE NETHERLANDS), Wouter van Solinge, Shabaz Mohammed, Martina<br />

O’Flaherty, Albert Heck, Monique Slijper<br />

Guided Gas-Phase Fractionation: A Strategy To Tackle Duty-Cycle Limitations<br />

Anne Rokka (Turku Centre for Biotechnology, University of Turku & Ãbo Akademi<br />

University, FINLAND), Aschwin van der Woude, Santosh Gupta, Matthias Nees,<br />

Garry Corthals<br />

P-MON-172<br />

P-MON-173<br />

P-MON-174<br />

New MS-Based Serum Pattern Diagnostics Method Using ZipTip Technology And<br />

Ultrafiltration<br />

Ali Tiss (BioCentre and Chemistry Department, University of Reading, UNITED KINGDOM),<br />

Celia Smith, John Timms, Zhiyuan Luo, Alex Gammerman, Usha Menon, Mike Waterfileld,<br />

Ian Jacobs, Rainer Cramer<br />

New Methodology Combining Hydrophobic Gel And FT-ICR MS/MS For Membrane<br />

Protein Analysis<br />

Caroline Tokarski (Umr Cnrs 8009, FRANCE), Marianne Fillet, Christian Rolando<br />

Selective Detection And Enrichement Of Serum Albumin In Human Erythrocyte<br />

And Urine By Capillary Electrophoresis<br />

Wei-Lung Tseng (Department of Chemistry, National Sun Yat-sen University-Kaohsiung<br />

Medical University Joint Research Center, TAIWAN)<br />

80 81


P-MON-175<br />

P-MON-176<br />

P-MON-177<br />

P-MON-178<br />

P-MON-179<br />

Dyes<br />

P-MON-180<br />

P-MON-181<br />

P-MON-182<br />

P-MON-183<br />

P-MON-184<br />

P-MON-185<br />

P-MON-186<br />

Ultrasonic Assisted Protein Enzymatic Digestion For Selenium Amino-Acids<br />

Gonçalo Vale (FCT-UNL, PORTUGAL)<br />

Potential Of Long Capillary Monolithic Columns For The Analysis Of Protein<br />

Digests<br />

Michiel H.M. van de Meent (Utrecht University, THE NETHERLANDS), Gerardus J.<br />

de Jong<br />

Reproducibility Of 2D Gel-Based Proteomics Experiments<br />

David Bramwell, Mary C. Hurley, Alamgir Khan, Katrin Marcus, Jules A. Westbrook,<br />

Hans Voshol (Novartis Institutes for BioMedical Research, SWITZERLAND)<br />

An Integrated M-IPG-CIEF-Microenzymatic Reactor-Cze Platform For Protein<br />

Analysis<br />

Tingting Wang (Dalian Institute of Chemical Physics, Chinese Academy of Sciences,<br />

CHINA), Zhen Liang, Lihua Zhang, Yukui Zhang<br />

Quantitative Proteomics for 2D Gel Electrophoresis using Multiple Saturation<br />

John Wiktorowicz (The University of Texas Medical Branch, UNITED STATES), Susan<br />

Stafford, Alexander Kurosky<br />

High Sensitivity Porous Sprayer (HSPS) In Capillary Electrophoresis-Mass<br />

Spectrometry (CE-MS) For The Analysis Of Phosphopeptides<br />

Catherine C.L. Wong (The Scripps Research Institute, UNITED STATES), Chitra<br />

Ratnayake, Jeff Chapman, John R. Yates III<br />

Single Drop Microextraction Using Ag Nanoparticles For Peptide Analysis In AP-<br />

MALDI-MS<br />

Hui-Fen Wu (National Sun Yat Sen University, TAIWAN)<br />

Miniaturized Two Dimensional Capillary Electrophoresis On Microchip For Protein<br />

Analysis<br />

Cong Yongzheng (National Chromatographic R. & A. Center, Dalian Institute of<br />

Chemical Physics, Chinese Academy of Sciences, CHINA), Zhang Lihua, Liang Yu,<br />

Zhang Weibing, Zhang Yukui<br />

Column Switch Recycling Size Exclusion Chromatography For High Efficient<br />

Protein Separation<br />

Huiming Yuan (National Chromatographic Reasearch and Analysis Center, Dalian<br />

Institute of Chemical, CHINA), Lihua Zhang, Zhen Liang, Yukui Zhang<br />

Withdrawn<br />

Development Of Multi-Dimensional Chromatography-Mass Spectrometry<br />

Techniques For Protein Complex Analysis<br />

Xiangmin Zhang (Department of Chemistry / Institutes of Biomedical Sciences,<br />

Fudan University, CHINA), Jia Tang, Mingxia Gao, Chunhui Deng<br />

A New Protein Equalizer Based on M13 scFv Displaying Library<br />

Peng Zhao (Dalian Institute of Chemical Physics, Chinese Academy of Sciences,<br />

CHINA), Lihua Zhang, Zhen Liang, Yukui Zhang<br />

Molecular Mass Imaging<br />

P-MON-187<br />

P-MON-188<br />

P-MON-189<br />

P-MON-<strong>19</strong>0<br />

P-MON-<strong>19</strong>1<br />

P-MON-<strong>19</strong>2<br />

P-MON-<strong>19</strong>3<br />

P-MON-<strong>19</strong>4<br />

P-MON-<strong>19</strong>5<br />

P-MON-<strong>19</strong>6<br />

P-MON-<strong>19</strong>7<br />

P-MON-<strong>19</strong>8<br />

Maldi Imaging Detection Of A MRI Contrast Agent In Mouse Liver<br />

Elena Acquadro (BioIndustry Park Canavese, ITALY), Davide Corpillo, Claudia Cabella,<br />

Luigi Miragoli, Enrico Maria Bucci<br />

From Lipids To Proteins In One Single Tissue<br />

Erika Amstalden van Hove (FOM Institute for Atomic and Molecular Physics, THE<br />

NETHERLANDS), Ivo Klinkert, Tiffany Greenwood, Kristine Glunde, Ron Heeren<br />

Digital Imaging Mass Spectrometer<br />

Andreas Bamberger (Physics Institute, Albert-Ludwigs University of Freiburg,<br />

Freiburg, GERMANY), Casimir Bamberger<br />

High-Efficiency Ion Mobility Coupled MALDI MS For Tissue Imaging Of<br />

Endogenous Compounds<br />

Emmanuelle Claude, Paul Trim, Marten F Snel (Waters Corporation, UNITED KINGDOM),<br />

Malcolm Clench, Therese McKenna, James Langridge<br />

Monitoring Drug And Metabolites In Tissue Using Fticr Imaging Mass Spectrometry<br />

Shannon Cornett (Vanderbilt University, UNITED STATES), Jens Fuchser, Michael<br />

Becker, Sara L. Frapier, Paul Speir, Richard M. Caprioli<br />

MALDI-FTMS For Small Molecule Molecular Imaging Of Cancer Targets At<br />

Therapeutic Dosages<br />

Michael Easterling (Bruker Daltonics, Inc., UNITED STATES), Nathalie Agar, Claire<br />

Sauvageot, Jeffrey Agar<br />

Distribution Of Platinum Salts Evidenced By The Direct Mass Spectrometry<br />

Analyses Of Tissues<br />

Christian Larroque (IRCM/CRLC, FRANCE), Nicole Bec, Amina Bouslimani, Frederic Pinguet<br />

Imaging MS/ms And On-Tissue Protein Identification<br />

Luke MacAleese (FOM Institute for Atomic and Molecular Physics (AMOLF), THE<br />

NETHERLANDS), Erika R. Amstalden v. Hove, Jonathan Stauber, Ron M.A. Heeren<br />

Localizing Allergenic Proteins On The Surface Of Natural Latex Gloves By Ms<br />

Imaging<br />

Martina Marchetti (Vienna University of Technology, AUSTRIA), Emmanuel Raptakis,<br />

Günter Allmaier<br />

Correlating MALDI Imaging Mass Spectrometry Datasets<br />

Liam McDonnell (Leiden University Medical Center, THE NETHERLANDS), Alexandra<br />

van Remoortere, Rene van Zeijl, Andre Deelder<br />

MALDI Imaging: A Systems Approach To Understanding Embryonic Development<br />

Céline Meriaux (University of Lille 1, Laboratoire de neuroimmunologie des annélides,<br />

MALDI Imaging Team, FRANCE), Maxence Wisztorski, Jocelyne Bruand, Julien Franck,<br />

David Bonnel, Vineet Bafna, Eduardo Macagno, Michel Salzet, Isabelle Fournier<br />

MALDI-MSI Of Prostate Tissues For Detection Of Cancer And Micrometastatic Disease<br />

Lisa Cazares, Raymond Lance, Savvas Mendrinos, Michael Williams, MaryAnn Clemments,<br />

Richard Drake, O. John Semmes (Eastern Virginia Medical School, UNITED STATES)<br />

P-MON-<strong>19</strong>9<br />

Electrospray-Assisted Laser Desorption Ionization (ELDI) Mass Spectrometry<br />

For Molecular Imaging Of Heart¡BLiver And Brain Tissues<br />

Jentaie Shiea, Min-Zong Huang (National Sun Yat-Sen University, TAIWAN), Hay-Yan<br />

Wang, Li-Hua Lo<br />

82 83


P-MON-200<br />

P-MON-201<br />

P-MON-202<br />

P-MON-203<br />

P-MON-204<br />

A Combined Imaging Mass Spectrometry And MRI Study Of Nanoparticle Based<br />

Drug Delivery Systems<br />

Jonathan S. Stauber (FOM AMOLF Inst. Atomic/molecular Physics, THE NETHERLANDS),<br />

Lennaert Klerk, Glenda S. van Bochove, Klaas Nicolay, Ron M.A. Heeren<br />

Targeted Ion Mobility Imaging Mass Spectrometry : A New Tool For In Situ Identification<br />

Jonathan Stauber, Basak Kükrer Kaletaş (FOM Inst. Atomic/molecular Physics, THE<br />

NETHERLANDS), Ingrid M. van der Wiel, Marten Snel, Emmanuelle Claude, Ron M.A.<br />

Heeren<br />

Hierarchical Clustering: A New Tool For The Evaluation Of MALDI Tissue Images<br />

Sören-O Deininger (Bruker Daltonics, GERMANY), Michael Becker, Marc Gerhard,<br />

Arne Fütterer, Detlev Suckau<br />

Molecular Imaging Of Abeta Peptides In Hereditary Cerebral Hemorrhage With<br />

Amyloidosis-Dutch Type<br />

Alexandra van Remoortere (Biomolecular Mass Spectrometry Unit, LUMC, THE<br />

NETHERLANDS), René J.M. van Zeijl, Liam A. McDonnell, Marion L.C. Maat-Schieman,<br />

Ingrid M. Hegeman-Kleinn, Sjoerd G. van Duinen, Kim S. Rutgers, Silvère M. van der<br />

Maarel, André M. Deelder<br />

Proteomic Content And Spatial Definition Of Endometriosis Tissue<br />

Anni Vehmas (Turku Centre for Biotechnology, University of Turku and Ãbo Akademi<br />

University, FINLAND), Anne Rokka, Garry Corthals<br />

Organelle And Biological Membranes Proteomics<br />

P-MON-205<br />

Searching For Respiratory Biomakers On The Membrane Proteome Of A Sulphate<br />

Reducing Bacterium<br />

Maria Gabriela Almeida (REQUIMTE - Faculdade Ciencias e Tecnologia/ Escola<br />

Superior de Saude Egas Moniz, PORTUGAL), Marta R. Santos, Isabel Moura, Celia<br />

M. Silveira, Jorge Lampreia<br />

P-MON-213<br />

P-MON-214<br />

P-MON-215<br />

P-MON-216<br />

P-MON-217<br />

P-MON-218<br />

P-MON-2<strong>19</strong><br />

P-MON-220<br />

Membrane Proteomics Of Gram-Positive Bacteria By Complementary Approaches<br />

Doerte Becher (Institute for Microbiology, University Greifswald, GERMANY),<br />

Susanne Wolff, Hannes Hahne, Michael Hecker<br />

Nuclear Proteome Of Rice Under Dehydration Reveals Predicted And Unexpected<br />

Proteins<br />

Mani Kant Choudhary, Debarati Basu, Asis Datta, Niranjan Chakraborty,<br />

Subhra Chakraborty (National Institute for Plant Genome Research, INDIA)<br />

Proteomics Of Molecular Chaperones And Chaperone-Like Proteins In Bacterial<br />

Membranes<br />

Srgjan Civciristov (The University of Melbourne, Department of Biochemistry and<br />

Molecular Biology, Bio21 Institute, AUSTRALIA), Xenia Gatsos, Nicholas Williamson,<br />

Anthony Purcell, Trevor Lithgow<br />

Isolation And Evaluation Of Different Peroxisomes Subppopulations From Rat Liver<br />

Markus Islinger, Afsaneh Abdolzade-Bavil, Sven Liebler, Christoph Eckerskorn (BD<br />

Diagnostics, GERMANY), Alfred Völkl, Gerhard Weber<br />

Quantitative Proteomic Analysis Of The Nuclear Matrix In Pre-B Cells<br />

Rudolf Engelke (MPI of Immunobiology, GERMANY)<br />

Using Quantitative Proteomics To Identify Proteins Important For Melanoma<br />

Transformation<br />

Vaughan Feisst (School of Biological Sciences, The University of Auckland, NEW ZEALAND)<br />

The Mitochondrial Proteome In Healthy Aging<br />

Marco Gallo (Medical Genetics - The University of British Columbia, CANADA), Aruna<br />

Somasiri, Peter Ruzanov, Leonard Foster, Donald Riddle<br />

Polyspecific Anti-Mitocondrion Antibodies For Proteomics On In Toto Tissue Homogenates<br />

Elisabetta Gianazza (Gruppo di Studio per la Proteomica e la Struttura delle Proteine,<br />

Milano, ITALY), Emanuele Loro, Silvia Cazzola, Robin Wait, Carmen Brizio, Lodovica Vergani<br />

P-MON-206<br />

P-MON-207<br />

P-MON-208<br />

P-MON-209<br />

P-MON-210<br />

P-MON-211<br />

Analysis Of Human Erythrocyte Membrane And Cytosolic Sub-Proteomes By 2-DE<br />

Gloria Alvarez-Llamas (Department of Immunology, Fundacion Jimenez Diaz, SPAIN),<br />

Fernando de la Cuesta, Veronica M. Darde, Maria G. Barderas, Fernando Vivanco<br />

Molecular And Functional Organization Of Yeast Peroxisomal Membrane Protein<br />

Complexes<br />

Hanna Amelina (Stockholm University, Department of Biochemistry and Biophysics,<br />

SWEDEN), Susana Cristobal<br />

Spatiotemporal Proteomics Analysis Of Autophagy<br />

Jens Andersen (University of Southern Denmark, DENMARK), Joern Dengjel, Anders Kristensen,<br />

Maria Hoeyer-Hansen, Soeren Gade-Joergensen, Jakob Bunkeborg, Marja Jaattela<br />

Proteome Versus Morphology: The Golgi Apparatuses Of Rat Liver And Spermatid.<br />

Catherine Au (McGill University, CANADA), Alexander Bell, Robert Kearney, Michael<br />

Hallett, Louis Hermo, Tommy Nilsson, John Bergeron<br />

Desperately Seeking Comprehensive Membrane Proteomics<br />

Mark Baker (Australian Proteome Analysis Facility, AUSTRALIA)<br />

Identification Of Plasma Membrane Proteins Of Human Spermatozoa<br />

Kathrin Bartho (Ruhr-University Bochum, GERMANY)<br />

P-MON-221<br />

P-MON-222<br />

P-MON-223<br />

P-MON-224<br />

P-MON-225<br />

Using Organelle Proteomics For The Identification Of Novel Anti-Aging Small Molecules<br />

Alexander Goldberg (Concordia University, Biology Department, CANADA)<br />

Detecting The Phospholipid-Interacting Proteome By Photocross-Linking And<br />

Click-Chemistry<br />

Jacob Gubbens (Utrecht University, THE NETHERLANDS), Eelco Ruijter, Ben de<br />

Kruijff, Monique Slijper, Rob Liskamp, Toon de Kroon<br />

Sub-Cellular Proteomic Analysis In Breast Cancer<br />

Nora Gutierrez-Najera (National Institute of Genomic Medicine (INMEGEN), MEXICO),<br />

Angel Alvarado-Nuño, Karla Calderon-Gonzalez, Jose Luis Cruz, Santiago March,<br />

Gerardo Jimenez, Jose Luis Gallegos-Perez<br />

Membrane Protein Interactome Of The Endoplasmatic Reticulum In Yeast<br />

Linnea Hedin (Center for Biomembrane Research / Biochemistry and Biophysics,<br />

Stockholm University, SWEDEN), Ã Björklund, Susana Cristobal, Arne Elofsson<br />

Quantitative Analysis Of Respiratory Chain Complexes During Anaerobic<br />

Conditions<br />

Andreas Helbig (Utrecht University, THE NETHERLANDS), Marco JL de Groot,<br />

Renske A. van Gestel, Pascalle Daran Lapujade, Albert Heck, Monique Slijper<br />

P-MON-212<br />

The Cell Surface Protein Atlas<br />

Damaris Bausch-Fluck (NCCR Neuro Center for Proteomics, IMSB, ETH Zurich,<br />

SWITZERLAND), Andreas Hofmann, Thomas Bock, Bernd Wollscheid<br />

P-MON-226<br />

Cell Surface Proteomics Of Blood Cancer Cells<br />

Andreas Hofmann (NCCR Neuro Center for Proteomics, Institute of Molecular Systems<br />

Biology, SWITZERLAND), Thomas Bock, Damaris Bausch-Fluck, Bernd Wollscheid<br />

84 85


P-MON-227<br />

P-MON-228<br />

Characterization Of Organelles By Protein Correlation Profiling (PCP) Combined<br />

With SILAC<br />

Lis Jakobsen (Center for Experimental Bioinformatics, University of Southern<br />

Denmark, DENMARK)<br />

Dige Analysis Of Ras-Transformed Fibroblast Cell-Derived Exosomes<br />

Hong Ji (Ludwig Institute for Cancer Research, AUSTRALIA), Bow Tauro, Eugene<br />

Kapp, Robert Moritz, Justin Lim, Richard Simpson<br />

P-MON-241<br />

P-MON-242<br />

Phase Transfer Surfactant-Aided Membrane Proteomics For Human Colon Cancer<br />

Takeshi Masuda (Institute for Advanced Biosciences, Keio University, JAPAN),<br />

Yasuyuki Igarashi, Hiroyasu Esumi, Tomoyoshi Soga, Masaru Tomita, Yasushi Ishihama<br />

Towards Interaction Networks Of Peroxisomal Membrane Proteins In Yeast<br />

Silke Oeljeklaus (Medizinisches Proteom-Center, Ruhr-Universität Bochum,<br />

GERMANY), Benedikt Reinartz, Michael Kohl, Christian Stephan, Wolfgang Schliebs,<br />

Ralf Erdmann, Helmut E. Meyer, Bettina Warscheid<br />

P-MON-229<br />

P-MON-230<br />

P-MON-231<br />

P-MON-232<br />

P-MON-233<br />

P-MON-234<br />

P-MON-235<br />

The Lpi Technology – New Tools And Methods For Membrane Protein Research<br />

Anders Karlsson (Nanoxis AB, SWEDEN)<br />

A Proteomic Approach Toward Comprehensive Expression Of Liver Membrane<br />

Protein Of Hcv Infected Pakistani Population<br />

Rizma Khan (Department of Biochemistry, University of Karachi, PAKISTAN), Saadia<br />

Zahid, Afshan Wasti, MA Rahman, Nikhat Ahmed<br />

Discovery Of Jak1 Involvement In Osteoclastogenesis By Proteomics<br />

Hong-Hee Kim (Seoul National University, KOREA), Youngkyun Lee, Jeong Im Ha,<br />

Seok-Won Hyung, Hee Jung Jung, Sang Won Lee, Zang Hee Lee<br />

Effects Of Fludarabine Or Cladribine On The Plasma Membrane Proteome Of<br />

Lymphoma Cells<br />

Philippa L. Kohnke (The University of Sydney, AUSTRALIA), Ben Crossett, Richard I.<br />

Christopherson<br />

Organellar Protein Localization By Quantitative Proteomics And Novel<br />

Bioinformatics<br />

Chanchal Kumar (Max Planck Institute for Biochemistry, GERMANY), Francesca<br />

Forner, Matthias Mann<br />

Quantitative Proteomics Analysis Of Amino Acid Induced Ribosome Biogenesis<br />

Katja Malene Larsen (Center for Experimental Bioinformatics, University of<br />

Southern Denmark, DENMARK)<br />

Enrichment Of Membrane Proteins By Phase Partitioning Combined With Lectin<br />

Affinity<br />

Albert Lee (Department of Chemistry and Biomolecular Sciences, Macquarie<br />

University, AUSTRALIA), Nicolle Packer, Paul Haynes, Daniel Kolarich, Pia Jensen,<br />

Mark Baker<br />

P-MON-243<br />

P-MON-244<br />

P-MON-245<br />

P-MON-246<br />

P-MON-247<br />

P-MON-248<br />

P-MON-249<br />

Enhanced Detergent Extraction For The Membrane Proteomic Analysis In<br />

Cyanobacteria<br />

Jeehyun Oh (Korea Basic Science Institute, KOREA), Joseph Kown, Seung Il Kim,<br />

Jong-Soon Choi<br />

Mitochondrial Proteomics For Identification Of Metabolic Unbalance And Cellular<br />

Stress<br />

Johan Palmfeldt (Aarhus University Hospital / Aarhus University, DENMARK), Søren<br />

Vang, Vibeke Stenbroen, Peter Bross, Niels Gregersen<br />

Down-Regulation Of Two Outer Membrane Proteins Tsx And OmpW Is Required<br />

For Iron Homeostasis In Escherichia Coli<br />

Xuanxian Peng (Sun Yat-sen University, CHINA), Xiangmin Lin, Lina Wu, Hui Li,<br />

Sanying Wang<br />

High Definition Proteomic Analysis Of Human Monocyte-Derived Macrophages<br />

(MDM)<br />

Rita Polati (University of Verona, Dip. Scientifico e Tecnologico, ITALY), Francesca<br />

Bonini, Alessandra Maria Bossi, Domenico Girelli, Annalisa Castagna<br />

Subcellular Fractionation In A Fluidic Microsystem<br />

Anton Posch (Bio-Rad Laboratories GmbH, GERMANY), Aran Paulus, Monika<br />

Hausmann, Nancy Kunz, Martin Stelzle, Meike Moschallski, Thanh Tu Duong, Gert<br />

Blankenstein<br />

Subcellular Proteomics Of Mucin-Containing Vesicles In Goblet Cells<br />

Ana M Rodriguez-Piñeiro (Gothenburg University, SWEDEN), Malin E.V. Johansson,<br />

Gunnar C. Hansson<br />

Glucotoxicity And Pancreatic ß-Cell Dysfunction<br />

Jean-Charles Sanchez (Geneva University, SWITZERLAND)<br />

P-MON-236<br />

P-MON-237<br />

P-MON-238<br />

P-MON-239<br />

P-MON-240<br />

Efficient Method To Identify Membrane Proteins By Introduction Of Chemical<br />

And Enzyme Reaction<br />

JeongEun Lee (Department of Molecular Medicine, KyungPook National University<br />

School of Medicine, KOREA), Joshep Kwon, Pyong-Gon Moon, Hyun-Ho Hwang, Moon-<br />

Chang Baek<br />

Deciphering Phosphoinositide Signalling Pathways In Nuclei By Identifying<br />

Effector Proteins<br />

Aurelia Lewis (PROBE proteomic platform, Dept of Biomedicine, NORWAY), Magnus<br />

Arntzen, Clive D’Santos<br />

Withdrawn<br />

Withdrawn<br />

Differential Proteomic Analysis Of Colorectal Cancer-Derived Exosomes<br />

Justin WE Lim (Ludwig Institute for Cancer Research / Department of Biochemistry<br />

and Molecular Biology, University of Melbourne, AUSTRALIA), Eugene A. Kapp,<br />

Robert L. Moritz, Richard J. Simpson<br />

P-MON-250<br />

P-MON-251<br />

P-MON-252<br />

P-MON-253<br />

Proteomic Analysis Of Oxidative Damage To Mitochondrial Complex I In<br />

Parkinson’s Disease<br />

Birgit Schilling (Buck Institute for Age Research, UNITED STATES), Srinivas Bharath,<br />

Steven R. Danielson, Jason M. Held, Julie K. Andersen, Bradford W. Gibson<br />

Quantitative Surface Proteome Analysis Of Pancreatic ß-Cells By Targeted Mass<br />

Spectrometry<br />

Alexander Schmidt (Institute of Molecular Systems Biology, ETH Zurich/ Competence<br />

Center for Systems Physiology and Metabolic Diseases, SWITZERLAND), Katrin<br />

Eckhardt, Carsten Danzer, Lukas Mueller, Bernd Wollscheid, Bruno Domon, Willy<br />

Krek, Ruedi Aebersold<br />

Blue Native Page Analysis Of A Mouse Liver Microsomal Fraction<br />

Faezeh Shekari (Royan institude, IRAN), Bill Jordan, Hossein Baharvand, Ghasem<br />

Hosseini Salekdeh<br />

A Novel System For Membrane Protein Expression And Purification<br />

Wei-Wei Zhang, Li Deng, Qian Ruan, Jenny Cui, Sergey Sikora (GenWay Biotech, Inc.,<br />

UNITED STATES), Xiangming Fang<br />

86 87


P-MON-254<br />

P-MON-255<br />

P-MON-256<br />

P-MON-257<br />

P-MON-258<br />

P-MON-259<br />

P-MON-260<br />

P-MON-261<br />

P-MON-262<br />

P-MON-263<br />

P-MON-264<br />

P-MON-265<br />

P-MON-266<br />

P-MON-267<br />

Quantitative Erythrocyte Membrane Proteome Analysis With Blue-Native/Sds Page<br />

Monique Slijper (Utrecht University, THE NETHERLANDS), Renske van Gestel, Albert<br />

Heck, Gert Rijksen, Richard van Wijk, Wouter van Solinge<br />

A Quantitative Proteomic Analysis Of The Dynamic Changes In Protein Profiles<br />

Of Lipid Rafts During T-Cell Signaling<br />

Therese Solstad (The Biotechnology Centre of Oslo, NORWAY), Margarita Strozynski,<br />

Kjetil Taskén, Bernd Thiede, Knut Martin Torgersen<br />

The Escherichia Coli Periplasmic Chaperone Sura Is Required For The Biogenesis<br />

Of Specific Beta-Barrel Proteins En Route For The Outer Membrane<br />

Didier Vertommen (UCL-de Duve Institute, BELGIUM), Pauline Leverrier, Jean-Francois<br />

Collet, Natividad Ruiz, Thomas Silhavy<br />

Two Novel Membrane Extraction Procedures: Liquid And Solid Phase Based Chemistry<br />

Joerg von Hagen (Merck KGaA, GERMANY), Uwe Michelsen, Maria Wehsling,<br />

Robertus Hendriks<br />

TolC, OmpC and LamB Are Critical Outer Membrane Proteins For Tetracycline<br />

Resistance In Escherichia Coli<br />

San-ying Wang (Xiamen University, CHINA), Dan-feng Zhang, Hui Li, Zhi-ming Xiang<br />

Study Of The Mouse Olfactory Receptor-Associated Proteome<br />

Jenny Adler, Jon Barbour, Silke Oeljeklaus, Astrid Tschapek, Eva M. Neuhaus, Hann<br />

H. Hatt, Helmut E. Meyer, Bettina Warscheid (Medizinisches Proteom-Center, Ruhr-<br />

Universitaet Bochum, GERMANY)<br />

Membrane Proteome Of S.Cerevisiae Vacuoles<br />

Elena Wiederhold (University of Groningen, THE NETHERLANDS), Tejas Gandhi,<br />

Hjalmar Permentier, Rainer Breitling, Dirk Jan Slotboom, Bert Poolman<br />

Membrane Proteomics Analysis Of Solvent Tolerance In Pseudomonas Putida S12<br />

Dorien Wijte (TNO, THE NETHERLANDS)<br />

Affinity Profiling Of Adenine Nucleotide-Binding Proteins<br />

Justina Clarinda Wolters (University Groningen, THE NETHERLANDS)<br />

Altered Membrane Proteomic Signature In Human Colorectal Cancer<br />

Chien-Peng Wu, Pei-Yi Lin, Chia-Feng Tsai, Chih-Wei Chien, Chia-Li Han, Chih-Chiang<br />

Tsou, Ting-Yi Sung, Wen-Lian Hsu, Yu-Ju Chen (Institute of Chemistry, Academia<br />

Sinica, TAIWAN)<br />

Gene Expression And Proteomic Profiling Of Induced Hepatotoxicity In Mice<br />

Victor Zgoda (Institute of Biomedical Chemistry, RUSSIAN FEDERATION), O Tikhonova,<br />

A Kopylov, L Kurbatov, A Archakov<br />

Proteomics Analysis Of Human Placenta Syncytiotrophoblast Apical Membrane<br />

Qi Zhang (Deutsch Forschungsgemeinschaft GRAKO845, GERMANY)<br />

Proteomics And Phosphoproteomics Of Human Skeletal Muscle Mitochondria<br />

Xiaolu Zhao (Protein Research Group, Department of Biochemistry and Molecular<br />

Biology, University of Southern Denmark, DENMARK), Ole Nørregaard Jensen, Kurt<br />

Højlund, Martin Mogensen<br />

Exploring The Caveolae Proteome Using Disease-Related Caveolin Mutants<br />

Yuzi(Emma) Zheng (University of British Columbia, CANADA), Leonard Foster,<br />

Masayuki Numata<br />

Quantification I<br />

P-MON-268<br />

P-MON-269<br />

P-MON-270<br />

P-MON-271<br />

P-MON-272<br />

P-MON-273<br />

P-MON-274<br />

P-MON-275<br />

P-MON-276<br />

P-Mon-277<br />

P-MON-278<br />

P-MON-279<br />

P-MON-280<br />

A Workflow For Quantitative Proteomic Analysis Of siRNA-Mediated Silencing In<br />

Human Cells<br />

Albina Abdrakhmanova (Applied Biosystems, GERMANY)<br />

Quantitative Phosphorylation Analysis Method By Enzyme-Assisted And<br />

Chemical Labeling Approach<br />

Yeong Hee Ahn (Division of Mass Spectrometry, Korea Basic Science Institute, KOREA),<br />

Ji Yeon Lee, Eun Sun Ji, Kun Cho, Hyun Ju Kang, Hoguen Kim, Jong Shin Yoo<br />

Protein Expression Analysis Of A Human Osteoblast Differentiation Model<br />

Rodrigo Alves (Department of Internal Medicine, Erasmus MC, THE NETHERLANDS),<br />

Marco Eijken, Sigrid Swagemakers, Peter Burgers, Mark Titulaer, Robert-Jan Lamers,<br />

Theo Luider, Johannes van Leeuwen<br />

A New Approach For Target Peptides Quantification<br />

Je-Hyun Baek (Korea Institute of Science and Technology, KOREA), Hokeun Kim, Myeong-Hee Yu<br />

Label-Free Comparison Of Complex Protein Samples<br />

Casimir Bamberger (The Scripps Research Institutes, UNITED STATES), Sandra<br />

Pankow, Tao Xu, Sung Kyu Park, John Yates<br />

Label-Free Quantification Of Affinity-Purified Proteins: Three Complementary<br />

Approaches And Their Software Integration<br />

Alexander Haupt, Martin L. Biniossek, Wolfgang Bildl (Institute of Physiology,<br />

University of Freiburg, GERMANY), Joerg O. Thumfart, Catrin S. Mueller, Franz<br />

Jehle, Bernd Fakler, Uwe Schulte<br />

Spectral Merging To Improve Peptide Identification And Quantitation<br />

Rosa Viner, Torsten Ueckert, Terry Zhang, Vlad Zabrouskov (Thermo Fisher<br />

Scientific, UNITED STATES)<br />

Psaq Strategy For Sensitive And Accurate Quantification Of Biomarkers In<br />

Serum And Food<br />

Virginie Brun (CEA / INSERM U880 Exploring the Dynamics of Proteomes, FRANCE),<br />

Michel Jaquinod, Alain Dupuis, Vinzenz Lange, Jacques-Antoine Hennekinne, Annie<br />

Adrait, Dorothee Lebert, Jerome Garin<br />

Speeding Up Peptide Isotopic 18o-Labeling With Ultrasonic Energy<br />

Ricardo Carreira (REQUIMTE-Departamento de Química, Faculdade de Ciências e<br />

Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, PORTUGAL), Raquel<br />

Rial-Otero, Carlos Lodeiro, José Capelo<br />

Errors In Peptide Quantification Due To Variability In Ion Measurements<br />

Brian Carrillo (McGill University, CANADA), Xiaoyong Wu, Pascal Pleynet, Daniel<br />

Boismenu, Sylvie Laboissiere, Robert Nadon, Robert E. Kearney<br />

Data Quality Of Label-Free LC-MS Differential Proteome Analysis<br />

Daniel Chamrad, Wolfgang Jabs, Klaus Marquart, Barbara Sitek, Kai Stuehler, Meyer<br />

Helmut, Carsten Baessmann, Martin Blueggel (Protagen AG, Dortmund, GERMANY)<br />

Quantification Of P53 Protein In Cancer Cells Treated With Doxorubicin<br />

Sun Kyu Choi (Chung Nam national university, KOREA), Jung Ok Park, Kwang Pyo Kim,<br />

Young Hwan Kim<br />

Time-Resolved Analysis Of Tnf-Alpha Signaling By Quantitative Proteomics And<br />

Phosphoproteomics<br />

Jesper V Olsen, Chunaram Choudhary (Max Planck Institute for Biochemistry, GERMANY),<br />

Chanchal Kumar, Sonja Krüger, Gaby Sowa, Florian Gnad, Juergen Cox, Matthias Mann<br />

88 89


P-MON-281<br />

Accessing Protein Dynamics In Complex Organisms<br />

Amy Claydon (Proteomics and Functional Genomics Group, University of Liverpool,<br />

UNITED KINGDOM), Michael Thom, Nick Bond, Kathryn Lilley, Jane Hurst, Rob<br />

Beynon<br />

P-MON-294<br />

High Throughput Quantitative Analysis Of A New Biomarker To Gh Abuse Using<br />

UPLC-MS/MS<br />

Richard Kay (HFL Ltd, Newmarket, UNITED KINGDOM), Jane Roberts, Graham Ball,<br />

Cristiana Velloso, Colin Creaser, Philip Teale<br />

P-MON-282<br />

P-MON-283<br />

P-MON-284<br />

P-MON-285<br />

P-MON-286<br />

P-MON-287<br />

P-MON-288<br />

P-MON-289<br />

P-mon-290<br />

Withdrawn<br />

A New Approach To Define The Relative Contribution Of Co-Migrating Proteins<br />

To Spot Intensity In 2d-Page<br />

Maarten Dhaenens (Ghent University, BELGIUM), Sofie Vandecasteele, Dieter Deforce<br />

Elucidating Rapamycin Molecular Action By Quantitative Proteomic Analysis In<br />

Yeast<br />

Marjorie Fournier (Stowers Institute for Medical Research, UNITED STATES),<br />

Norman Pavelka, Ariel Paulson, Mihaela Sardiu, Christopher Seidel, Karin Zueckert-<br />

Gaudenz, Laurence Florens, Michael Washburn<br />

Iodine-Tagged Proteomics(Metallomics) Of Human Serum. Quantitative<br />

Iodoproteomics<br />

Tamara Garcia-Barrera (Universidad De Huelva, Spain), Elisa Gomez de las Heras,<br />

Jose Luis Gomez-Ariza<br />

Robust Protein Quantification In Mass Spectrometry<br />

Gregory Strubel, Caroline Paulus, Emeline Mery, Laurent Gerfault (Cea/Grenoble<br />

LETI/DTBS, FRANCE), Florence Ricoul, Jean-Francois Giovannelli, Pierre Grangeat<br />

8-Plex itraq Facilitated Proteomic Analysis Of Human Prostate Cancer Cells<br />

Adam Glen (Academic Urology, School of Medicine and Biomedical Science, University<br />

of Sheffield, UNITED KINGDOM), Chee Sian Gan, Freddy Hamdy, Colby Eaton, Simon<br />

Cross, Philip Wright, Ishtiaq Rehman<br />

The Ins And Outs Of 15N Labeling<br />

Joost Gouw (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />

University, THE NETHERLANDS), Bas Tops, Peter Mortensen, Albert Heck, Jeroen<br />

Krijgsveld<br />

ICPL (Isotope-coded Protein Labelling) QUADRUPLEX Technology For<br />

Quantitative Proteomics<br />

Thomas M. Halder (TopLab, GERMANY), Michael Kersten, Achim Brunner, Eva-Maria<br />

Keidel, Barbara Mueller, Josef Kellermann, Friedrich Lottspeich<br />

Quantitative Proteomic Analysis Of The Secretome During Myogenesis<br />

Jeanette Henningsen (Centre of Inflammation and Metabolism, University of<br />

Copenhagen, DENMARK)<br />

P-MON-295<br />

P-MON-296<br />

P-MON-297<br />

P-MON-298<br />

P-MON-299<br />

P-MON-300<br />

P-MON-301<br />

P-MON-302<br />

P-MON-303<br />

Protein Expression Changes In Human Neuroblastoma Cells Treated With<br />

Azaspiracid-1<br />

Ralf Kellmann (Department of Molecular Biology, The University of Bergen, NORWAY),<br />

Toril A. Groenset, Kari E. Fladmark<br />

Quantitative Synaptic Proteome Analysis In A Transgenic Migraine Mouse Model<br />

Expressing Mutated Cav.2.1 Channels<br />

Oleg Klychnikov (Biomolecular Masspectrometry Unit, Dept. Parasitology LUMC, THE<br />

NETHERLANDS), Oleg Mayboroda, Ka Wan Li, Igor Sidorov, Sabine Spijker, <strong>August</strong><br />

Smit, Rune Frants, Michel Ferrari, Andre Deelder, Arn Maagdenberg<br />

Label-Free Absolute Quantitative Analysis In Mass Spectrometry<br />

Arthur Kopylov (Institute of Biomedical Chemistry RAMS, RUSSIAN FEDERATION),<br />

V Zgoda, A Archakov<br />

The SILAC-Mouse: A New Tool For Quantitative Proteomics In Vivo<br />

Marcus Krüger (Max-Planck-Inst. for Heart and Lung Research, GERMANY), Markus<br />

Moser, Siegfried Ussar, Christian Luber, Franscesca Forner, Sara Zanivan, Sara<br />

Schmidt, Thomas Braun, Rheinhard Fässler, Matthias Mann<br />

MRM Based, Multiplexed, Absolute Quantitation Of 32 Proteins In Human Plasma<br />

Michael Kuzyk (University of Victoria - Genome BC Proteomics Centre, CANADA),<br />

Derek Smith, Tyra Cross, Juncong Yang, Angela Jackson, Darryl Hardie, Leigh<br />

Anderson, Christoph Borchers<br />

The Effect Of Heat Treatment On The Degradation Of Proteins In Brain Tissue<br />

Alastair Lang (Glasgow University, UNITED KINGDOM), Richard Goodwin, Andrew Pitt<br />

The Path To Absolute Protein Quantification Using LC-MS<br />

Jim Langridge (Waters Corporation, UNITED KINGDOM), Martha Stapels, Scott<br />

Geromanos, Hans Vissers, Hans Aerts<br />

Mesothelial Cell Stress Response To Peritoneal Dialysis Fluid<br />

Michael Lechner (Institute of Analytical Chemistry and Food Chemistry, University of<br />

Vienna, AUSTRIA), Klaus Kratochwill, Michaela Endemann, Christian Siehs, Kurt R.<br />

Herkner, Bernd Mayer, Christoph Aufricht, Andreas Rizzi<br />

Building A Repository Of Validated Mrm-Transitions For Targeted Pathway Biology<br />

Johan Lengqvist (Karolinska Biomics Center, SWEDEN), Lukas Orre, Janne Lehtiö<br />

P-MON-291<br />

Detection Frequency For Peptide Quantitation In Replicate LC-MS Runs<br />

Kosaku Shinoda, Naoyuki Sugiyama, Masaru Tomita, Yasushi Ishihama (Keio<br />

University, JAPAN)<br />

P-MON-292<br />

Differential Proteome Analysis Using Targeted Label-Free And SDS-PAGE ICPL<br />

Workflows<br />

Wolfgang Jabs, Markus Lubeck, Marina Behrens (Bruker Daltonik GmbH, GERMANY),<br />

Daniel Chamrad, Barbara Sitek, Sebastian Link, Christian Stephan, Kai Stühler,<br />

Helmut Meyer, Carsten Baessmann<br />

P-MON-293<br />

Proteomic Profiling for Human Pancreatic ß-Cell Line RNAKT-15 During Islet<br />

Formation<br />

Jonghwa Jin (Seoul National University College of Medicine, KOREA), Yup Kang,<br />

Heesook Jun, Youngsoo Kim<br />

90 91


Reagents For Proteomics<br />

Standards For Clinical Proteomics<br />

P-MON-304<br />

P-MON-305<br />

P-MON-306<br />

P-MON-307<br />

P-MON-308<br />

Withdrawn<br />

Mining Low Abundant Proteins From Congestive Heart Failure Sera Using<br />

Affinity Depletion<br />

Haiying Chen (Agilent Technologies, inc., UNITED STATES), Peter Mrozinski, Nina<br />

Zolotarjova, James Martosella<br />

Captureselect Ligands: Depletion Of Abundant Blood Proteins<br />

Frank Detmers (BAC BV, THE NETHERLANDS)<br />

DY-Maleimide Labeling: A Time Saving And Easy Handling Quantification Method<br />

Lisa Dietz (University of Heidelberg, Centre for Medical Research Mannheim,<br />

Department of Dermatology, Research Group Immunology & Proteomics,<br />

GERMANY), Patrick Pankert, Alberto Bosque, Stefanie Helm, Alberto Anel, Martina<br />

Schnoelzer, Hermann-Josef Thierse<br />

Withdrawn<br />

P-MON-3<strong>19</strong><br />

P-MON-320<br />

P-MON-321<br />

P-MON-322<br />

Proteome Analysis Of Chronic Wound Fluids Via Mudpit<br />

Caroline Chojnacki (Ruhr-University-Bochum, GERMANY)<br />

Quantitative Proteomics Plus Toponomics: Searching For Mamma Carcinoma<br />

Protein Signatures<br />

Claudia Peters, Cornelia Koy, Hans Vissers, Marc Kipping, Toralf Reimer, Michael<br />

Kreutzer, Bernd Gerber, James Langridge, Hans-Jürgen Thiesen, Michael O. Glocker<br />

(Proteome Center Rostock, University of Rostock, GERMANY)<br />

The HUPO BPP Wish List<br />

Michael Hamacher (Ruhr-Universitaet Bochum, Medizinisches Proteom-Center,<br />

GERMANY), Christian Stephan, Tanja Hardt, Martin Eisenacher, Katrin Marcus,<br />

Dominic Desiderio, Howard Gutstein, Young Mok Park, Joachim Klose, Helmut E. Meyer<br />

Statistical Analyses Of Proteomic Data For The Clinical Utility Of Protein<br />

Biomarkers<br />

Takao Kawakami (Tokyo Medical University, JAPAN), Atsushi Ogiwara<br />

P-MON-309<br />

P-MON-310<br />

P-MON-311<br />

P-MON-312<br />

P-MON-313<br />

P-MON-314<br />

P-MON-315<br />

P-MON-316<br />

P-MON-317<br />

P-MON-318<br />

Withdrawn<br />

Lys-N Metallopeptidase: A Tool For Straightforward De Novo Peptide Sequencing<br />

Albert Heck (The Netherlands Proteomics Centre, THE NETHERLANDS), Nadia<br />

Taouatas, Paul Boersema, Maarten Altelaar, Shabaz Mohammed, Madalina Drugan,<br />

Bas van Breukelen<br />

In Situ Proximity Ligation Assay For Detection Of Phosphorylated PDGFRB<br />

Malin Jarvius (Uppsala University, Molecular Medicine, SWEDEN), Irene Weibrecht,<br />

Karl-Johan Leuchowius, Ulf Landegren, Ola Söderberg<br />

Characterization Of Monoclonal Antibodies Specific For K48 Or K63 Poly-<br />

Ubiquitin Chains<br />

Jennie R. Lill (Genentech Inc, UNITED STATES), Kim Newton, Marissa Matsumoto,<br />

Ingrid E. Wertz, Donald Kirkpatrick, Vishva M. Dixit<br />

Polyclonal Antibody Generation - Correlations With Immunogen Solubility<br />

Jenny Ottosson (Royal Institute of Technology, SWEDEN), Johanna Steen, Sophia Hober<br />

Antibody Qa Pipeline For Proteomics Researchers: Nci’s Antibody<br />

Characterization Program<br />

Henry Rodriguez (National Cancer Institute/National Institutes of Health, UNITED<br />

STATES), Mehdi Mesri, Gordon Whiteley, Chris Kinsinger<br />

Complementary Immobilized Proteases And Ms/Ms Methods Improve Ptm<br />

Characterization<br />

Krystal Rampalli, Michael Rosenblatt, Marty Wilkes, Paul Haney, Roger Beringer,<br />

Andreas Huhmer, John Rogers (Thermo Scientific, UNITED STATES)<br />

Improved Protein Analysis With The New Mass Spectrometry-Compatible<br />

Surfactant<br />

Sergei Saveliev (Promega Corporation, UNITED STATES)<br />

Evaluating Proteolytic Peptide Characteristics Using Etd For De Novo Sequencing<br />

Nadia Taouatas (UU, THE NETHERLANDS), Madalina Drugan, Albert Heck, Shabaz<br />

Mohammed<br />

An Engineered Fusion Tag For Enhanced Protein Solubilization And Purification<br />

Marjeta Urh (Promega Corporation, UNITED STATES)<br />

P-MON-323<br />

P-MON-324<br />

P-MON-325<br />

P-MON-326<br />

P-MON-327<br />

P-MON-328<br />

P-MON-329<br />

P-MON-330<br />

Assessment And Development Of Proteomic Technologies For Clinical<br />

Applications In Cancer<br />

Christopher R. Kinsinger (NCI/NIH, UNITED STATES), Mehdi Mesri, Henry Rodriguez<br />

Comparative Proteomics Of The Stress Response Of Primary Omental Cells And<br />

An Immortalized Mesothelial Cell Line To Peritoneal Dialysis Fluids<br />

Klaus Kratochwill (Department of Pediatrics, Medical University of Vienna, AUSTRIA),<br />

Michael Lechner, Thorsten O. Bender, Bernd Mayer, Kurt R. Herkner, Andreas Rizzi,<br />

Christoph Aufricht<br />

Withdrawn<br />

Development Of Mass Spectrometry Protein Standards Using Sequence-Validated<br />

Human Open Reading Frames<br />

Mahbod Hajivandi, Thomas Beardslee, Carla Dhillon, Ganin Meredith, R Marshall Pope,<br />

Paul Predkiu (Invitrogen, UNITED STATES), Alexander Bell<br />

Absolute Protein Quantification And Traceability To The Si<br />

Caroline Pritchard (LGC, UNITED KINGDOM), Will Burkitt, Milena Quaglia, Cristian<br />

Arsene, Andre Henrion, Ruediger Ohlendorf, Gavin O’Connor<br />

Novel Inactivation Technology Stabilizes The In Vivo Levels Of Proteins, Peptides<br />

And Phosphorylations In Tissue Samples<br />

Marcus Svensson (Denator AB, SWEDEN), Mats Borén, Maria Fälth, Per Andrén,<br />

Per Svenningsson, Karl Sköld<br />

Proteomic Patterns Predict Acute Graft-Versus-Host Disease – An Intervention Trial<br />

Eva-Maria Weissinger (Hannover Medical School, Dept. Hematology, Hemostasis, and<br />

Oncology, GERMANY), Arnold Ganser, Eric Schiffer, Harald Mischak<br />

Proteomic Approach Of Glomerulus Microdissected From Biopsy Samples Of<br />

Human Kidney<br />

Ryo Koda (Department of Structural Pathology, Institute of Neprhology, Niigata<br />

Graduate Sc / Division of Clinical Nephrology and Rheumatology, Niigata Graduate<br />

School of Medical and Detal Sciences, JAPAN), Yutaka Yoshida, Izumi Taguchi,<br />

Masayuki Tasaki, Bo Xu, Ying Zhang, Eishin Yaoita, Ichiei Narita, Fumitake Gejyo,<br />

Tadashi Yamamoto<br />

92 93


Stem Cell Proteome Biology<br />

P-MON-331<br />

P-MON-333<br />

P-MON-334<br />

P-MON-335<br />

P-MON-336<br />

Manually Curetted Protein Chip Analysis Of Pluripotency-Associated Proteins In<br />

NIH3T3 Cells<br />

Kwang-Hyun Baek (Pochon CHA University, KOREA), Brijesh Ajjappala, Bharathi<br />

Suresh, Jae-Hwan Kim, Eung-Yoon Kim, Incheol Kang<br />

Dioxin Affects Osteoblast Differentiation From Bone Marrow Stem Cells:a<br />

Proteomic Study<br />

Donatella Carpi (Istituto di Ricerche farmacologiche Mario Negri, ITALY), Merja<br />

Korkalainen, Luisa Airoldi, Roberto Fanelli, Juha Tuukkannen, Matti Viluksela, Roberta<br />

Pastorelli<br />

A Proteomics Strategy To Detect Betai Pkc Substrates In Embryonic Stem Cells<br />

Helio Costa-Juinor (Laboratory of Genetics and Molecular Cardiology Heart Institute<br />

InCor-HCFMUSP, BRAZIL), Jose Eduardo Krieger, Daria Mochly-Rosen, Deborah<br />

Schechtman<br />

Withdrawn<br />

G-CSF Stimulates Expression Of Non-Phosphorylated Stathmin In Hematopoietic<br />

Stem Cells<br />

Thomas Franz (European Molecular Biology Laboratory, GERMANY), Volker Eckstein,<br />

Xinping Li, Stefan Leicht, Rainer Saffrich, Heinrich Lannert<br />

P-MON-343<br />

P-MON-344<br />

P-MON-345<br />

P-MON-346<br />

P-MON-347<br />

Proteomic Analysis Of Tumorigenic And Non-Tumorigenic Liver Cancer Cells<br />

Isolated From Huh-7 Cell Line<br />

Eun-Kyung Lee (Korea University, KOREA), Gi-Yeon Han, Mi-Ryung Kim, Hye Won<br />

Park, Chan-Wha Kim<br />

Quantification Of Early Signaling Events In Embryonic Stem Cell Self-Renewal<br />

Yu Lu, Scott B. Ficarro, Yi Zhang, Manor Askenazi, Elzbieta Hyatt, Leah Boyer,<br />

Thorsten Schlaeger, Chance John Luckey, Jarrod A. Marto (Department of Cancer<br />

Biology, Dana-Farber Cancer Institute / Department of Biological Chemistry and<br />

Molecular Pharmocology, Harvard Medical School, UNITED STATES)<br />

Proteomic Characterization Of Circulating Human Vascular Progenitors<br />

Ursula Mayr (Cardiovascular Division, King’s College London, UNITED KINGDOM),<br />

David Simper, Xiaoke Yin, Carmen Urbich, Anna Zampetaki, Marianna Prokopi,<br />

Michael Mueller, Ulli Benbow, Robin Wait, Manuel Mayr<br />

Identification Of New Cell Surface Markers For Human Neural Stem/Progenitor<br />

Cells<br />

Aavo-Valdur Mikelsaar (Institute of General and Molecular Pathology, University of<br />

Tartu/ LabAs Ltd, ESTONIA), Alar Sünter, Peeter Toomik, Kalmer Karpson, Erkki<br />

Juronen<br />

Phosphorylation Dynamics During Differentiation Of Embryonic Stem Cells<br />

Javier Munoz (Utrecht University, THE NETHERLANDS)<br />

P-MON-337<br />

P-MON-338<br />

P-MON-339<br />

P-MON-340<br />

P-MON-341<br />

P-MON-342<br />

Quantative Proteomics Analysis Of Down Syndrome Using Mouse Es Cell Model<br />

William Griffiths (School of Medicine, Swansea University, UNITED KINGDOM), Yuqin<br />

Wang, Dean Nizetic, Jurgen Groet<br />

Pr<strong>event</strong>ion Of Amino Acid Conversion In Silac Experiments With Embryonic<br />

Stem Cells<br />

Christopher Hughes (University of Western Ontario, CANADA), Sean Bendall, Gilles<br />

Lajoie<br />

The Effect Of Low Glucose On Human Bone Marrow Derived Mesenchymal Stem<br />

Cells<br />

Bo Ram Ji (KOREA University, KOREA), Ji Soo Kim, Mi Ryong Kim, Hye Won Park,<br />

Chan Wha Kim<br />

Comparative Analysis Of Secretome Of Adipose-Derived Stem Cells During<br />

Adipogenesis<br />

Jaeyoon Kim (Division of Molecular and Life Science, Pohang University of Science<br />

and Technology, KOREA), Yoon Sup Choi, Jae-Ho Kim, Pann-Ghill Suh, Sung Ho Ryu,<br />

Taehoon G. Lee<br />

Depot Specific Proliferation-Related Proteins In Bovine Adipose Stromal<br />

Vascular Cells<br />

Seulmina Kwon (National Institute of Animal Science, KOREA), Sujin Park, Mirim<br />

Park, Enjung Jang, Mina Park, Ssanggoo Cho, Dongwoon Kim, sunggoo Hong,<br />

Hyunjung Lee<br />

Application Of A Iterative Exclusion (IE)-MS Analysis to Human Embryonic Stem<br />

Cells<br />

Gilles Lajoie (University of Western Ontario, CANADA), Sean Bendall, Chris Hughes,<br />

Mickie Bhatia, Morag Stewart<br />

P-MON-348<br />

P-MON-349<br />

P-MON-350<br />

P-MON-351<br />

P-MON-352<br />

P-MON-353<br />

Proteomic Analysis Of The Effects Of Bmp4 Exposure On Human Embryonic<br />

Stem Cells<br />

Gilbert Omenn (University of Michigan, UNITED STATES), Anastasia Yocum, Theresa<br />

Gratsch, Nancy Leff, John Strahler, Angela Walker, George Michailidis, K Sue<br />

O’Shea, Philip Andrews<br />

Proteomic Analysis Of Bovine Muscle Satellite Cells During Adipogenic<br />

Differentiation<br />

Mi-Rim Park (National Livestock Research Institute, KOREA), Su-Jin Park, Seulmina<br />

Kwon, Eung-Jung Jang, Dong-Woon Kim, Hyun-Jung Lee<br />

Integrated Approach To Study Protein Expression In Mouse Embryonic Stem Cells<br />

KS Setty Rakesh, Minoru S.H. Ko, Dawood Dudekula, Ramaiah Nagaraja,<br />

Ravi Sirdeshmukh (Centre for Cellular and Molecular Biology, INDIA)<br />

Comparative Proteome And Transcriptome Analysis Of Human, Mouse, And<br />

Monkey Escs During Differentiation<br />

Ghasem Salekdeh (Royan Institute, IRAN)<br />

Studies Of Krab Znf Genes Differentially Expressed In Induced Pluripotent Stem<br />

Cells (IPS)<br />

Hans-Juergen Thiesen (Institute of Immunology, University of Rostock, GERMANY),<br />

Peter Lorenz, Michael Kreutzer, Cristina Al-Khalili Szigyarto, Matthias Uhlén, Guohui<br />

Ding, Yixue Li<br />

Comparative Transcriptomics And Proteomics Of Fetal And Adult Human Liver<br />

Konstantin Yarygin (Institute of Biomedical Chemistry RAMS, RUSSIAN<br />

FEDERATION), I Cheglakov, L Kurbatov, I Toropygin, A Archakov, G Sukhikh, G<br />

Vartanian<br />

94 95


Structural Proteomics<br />

P-MON-354<br />

P-MON-355<br />

P-MON-356<br />

Characterization Of The Fc And Fab Parts Of Recombinant- And Plasma Derived<br />

Polyclonal- Antibodies By MALDI Mass Spectrometry<br />

Omar Belgacem (Shimadzu Biotech, UNITED KINGDOM), Emmanuel Raptakis, Gerald<br />

Stubiger, Andrea Buchacher, Katharina Pock<br />

Cross-Linking Analysis Of Affinity-Purified Multi-Protein Complexes<br />

Zhuo Chen (University of Edinburgh, UNITED KINGDOM), Morten Rasmussen, Salman<br />

Tahir, Sjaak van der Sar, Kevin G. Hardwick, Juri Rappsilber<br />

Effects Of Low Ph On Amyloid-Fibrillation Of A Beta2-Microglobulin Variant<br />

Dorthe Corlin (Statens Serum Institut, DENMARK)<br />

P-MON-368<br />

P-MON-369<br />

P-MON-370<br />

Specific Enrichment Of Cross-Linked Peptides From Complex Mixtures<br />

Lau Sennels (Wellcome Trust Centre for Cell Biology, University of Edinburgh,<br />

UNITED KINGDOM), Adam Belsom, Mark Bradley, Juri Rappsilber<br />

Membrane Topology Of Monotopic Proteins: Shaving Off Biological Membranes<br />

Illarion Turko (Center for Advanced Research in Biotechnology, UNITED STATES),<br />

Natalia Mast, Wei-Li Liao, Irina Pikuleva<br />

Software Supported Top-Down Protein Sequence Characterization And<br />

Assignment Of Termini<br />

Lars Vorwerg, Anja Resemann (Bruker Daltonik GmbH, GERMANY), Detlev Suckau<br />

P-MON-357<br />

P-MON-358<br />

P-MON-359<br />

P-MON-360<br />

P-MON-361<br />

P-MON-362<br />

P-MON-363<br />

P-MON-364<br />

P-MON-365<br />

P-MON-366<br />

P-MON-367<br />

Contribution Of Human Telomerase Processivity To Telomere Length Maintenance<br />

Yasmin D’Souza (Lady Davis Institute, Jewish General Hospital, CANADA), Sophie<br />

Dupuis, Chantal Autexier<br />

Surface Mapping Of Human Cystathionine Beta-Synthase By Chemical<br />

Modification Of Amino Acids<br />

Ales Hnizda (Institution of metabolic disorder, 1st Medical Faculty, CZECH REPUBLIC),<br />

Viktor Kozich<br />

Rapid Assignment Of Disulfide Linked Peptides Utilizing Automatic A1 Ion Screening<br />

Sheng Yu Huang (Life Science business unit, C Sun MFG. LTD., TAIWAN), Chien Hsien<br />

Wen, Ding Tzai Li, Fong Ku Shi<br />

Caveolar Traffic Of Birch Pollen Allergen Bet V 1 Through Nasal Epithelium In<br />

Allergic Patients<br />

Risto Renkonen (Haartman Institute, University of Helsinki, FINLAND), Sakari<br />

Joenväärä, Pirkko Mattila, Antti Mäkitie, Sanna Salmi, Jutta Renkonen<br />

IMGT Colliers De Perles For Standardized Analysis Of V, C And G Type Domains<br />

François Ehrenmann (IMGT, the international ImMunoGeneTics information system,<br />

FRANCE)<br />

Conformational Changes In The P22 Portal Observed By Mass Spectrometry<br />

Kristina Lorenzen (UU, THE NETHERLANDS)<br />

Beyond Bottlenecks In Membrane Protein Overproduction In Lactococcus Lactis<br />

Ravi Kanth Reddy Marreddy (University of Groningen, THE NETHERLANDS), Joao<br />

P.C. Pinto, Eric R. Geertsma, Jan Kok, Bert Poolman<br />

Monitoring Protein Interactions By Bimolecular Fluorescence Complementation<br />

And Flow Cytometry<br />

Montserrat Morell (Institut Biotecnologia i Biomedicina - UAB, SPAIN), Alba<br />

Espargaro, Francesc Xavier Aviles, Salvador Ventura<br />

Novel Reagents For Structural Proteomics Crosslinking Applications<br />

Evgeniy Petrotchenko (UVic-Genome BC Proteomics Center, CANADA), Jamie Thomas,<br />

Christoph Borchers<br />

Profiling A Proteome For Hyperstable Proteins And Cellular Processes<br />

Vesna Prosinecki (Instituto Tecnologia Química e Biológica, Universidade Nova de<br />

Lisboa, PORTUGAL), Trong Khoa Pham, Phillip C. Wright, Claudio M. Gomes<br />

Identification Of Cross-Linked Peptides In Proteomic-Scale Experiments<br />

Juri Rappsilber (University of Edinburgh, UNITED KINGDOM), Morten Rasmussen,<br />

Salman Tahir, Zhuo Chen<br />

96 97


Poster Listing<br />

<strong>Tuesday</strong> <strong>19</strong> august<br />

Alternative Splicing & Protein Processing<br />

P-TUE-001<br />

P-TUE-002<br />

P-TUE-003<br />

P-TUE-004<br />

P-TUE-005<br />

P-TUE-006<br />

P-TUE-007<br />

P-TUE-008<br />

P-TUE-009<br />

P-TUE-010<br />

P-TUE-011<br />

P-TUE-012<br />

Search For Protein Over-Expression In Micro-Organisms Using Proteomics Tools<br />

Michiel Akeroyd (Dsm, THE NETHERLANDS)<br />

Protein N-Alpha-Acetylation Analyzed By N-Terminal Cofradic<br />

Thomas Arnesen (University of Bergen, NORWAY), Petra van Damme, Bogdan<br />

Polevoda, Kenny Helsens, Rune Evjenth, Jan Erik Varhaug, Joël Vandekerckhove,<br />

Johan R. Lillehaug, Fred Sherman, Kris Gevaert<br />

Withdrawn<br />

The Ligandome Of Non-Classical Mhc On Tumor Escape Variants<br />

Arnoud de Ru (Lumc, THE NETHERLANDS), Bianca Querido, Frits Koning, Thorbald<br />

van Hall, Peter van Veelen<br />

Isolation Of Protein Isoforms By Free Flow Electrophoresis Preserving Biological<br />

Activity<br />

Afsaneh Abdolzade-Bavil (Bd Diagnostics, GERMANY), Christian Obermaier, Siegfied<br />

Hirler, Ute Sukop, Gerhard Weber, Mikkel Nissum, Christoph Eckerskorn<br />

Alternative Splicing Of Tissue Factor And enos In Tnf-á Stimulated Human<br />

Endothelial Cells<br />

Andreas Eisenreich (Charitè – Universitätsmedizin Berlin, Campus Benjamin Franklin,<br />

Centrum Für Herz- Und Kreislaufmedizin, GERMANY), Vladimir Bogdanov, Heinz-<br />

Peter Schultheiss, Ursula Rauch<br />

Ppr: The Protein Processing Resource<br />

Niklaas Colaert (Department of Medical Protein Research / Department of<br />

Biochemistry, Ghent University, BELGIUM), Lennart Martens, Joël Vandekerckhove,<br />

Kris Gevaert<br />

The Human Protein Atlas - A Resource For Discovery And Validation Of<br />

Biomarkers<br />

Caroline Kampf (Uppsala University, SWEDEN), Anna Asplund, Kenneth Wester,<br />

Mathias Uhlén, Fredrik Ponten<br />

Further Improvement Of A Novel Method For C-Terminal Sequence Analysis In<br />

The Proteomic Era<br />

Pablo Moerman (Ghent University, BELGIUM)<br />

Comparison Of Secreted Protein Expression From Hepg2 Cells Exposed To<br />

2,3,7,8-Tetrachlorodibenzo-P-Dioxin And 2,3,4,7,8-Pentachloro Dibenzofuran<br />

Sohee Phark (KOREA University, KOREA), Seonyoung Choi, Zhi Zheng, Eunkyoung Jo,<br />

Min Lee, So-Young Park, Donggeun Sul<br />

Recipes For Resolved Electrophoresis Gels From Pure Chemicals<br />

Naziha Chirani (Université Des Sciences Et Technologies De Lille, FRANCE), Caroline<br />

Tokarski, Christian Rolando<br />

Targeted Analysis Of Protein Termini<br />

Bas van Breukelen (Uu, THE NETHERLANDS), Wilma Dormeyer, Shabaz Mohammed,<br />

Jeroen Krijgsveld, Albert Heck<br />

P-TUE-013<br />

P-TUE-014<br />

Biomarkers Ii<br />

P-TUE-015<br />

P-TUE-016<br />

P-TUE-017<br />

P-TUE-018<br />

P-TUE-0<strong>19</strong><br />

P-TUE-020<br />

P-tue-021<br />

P-TUE-022<br />

P-TUE-023<br />

P-TUE-024<br />

P-TUE-025<br />

A Proteomics Approach To Identification Of Minor Histocompatibility Antigens<br />

Peter van Veelen (Lumc, THE NETHERLANDS), Michel Kester, Kees van Bergen,<br />

Frits Koning, Harm Nijveen, Jack Leunissen, Arnoud de Ru<br />

Quantitative Glyco-Proteomics Detects Macrophage Release Of Inflammatory<br />

Mediators Following Activation<br />

Wei Yan, Ivan Gomez, Zhiyuan Hu, Hamid Mirzaei, Alexander Schmidt, Elaine Raines,<br />

Reudi Abersold (Institute For Systems Biology, UNITED STATES / Institute of<br />

Molecular Systems Biology / Faculty of Science, University of Zurich, SWITZERLAND)<br />

The Comprehensive Proteomic Analyses For The Discovery Of Novel Markers Of<br />

Alcohol Abuse<br />

Fumio Nomura (Department of Molecular Diagnosis, Graduate School of Medicine,<br />

Chiba University, Division of Laboratory Medicine, Clinical Genetics and Proteomics,<br />

Chiba University Hospital, JAPAN), Kazuyuki Sogawa, Takeshi Tomonaga, Yoshio<br />

Kodera, Tadakazu Maeda<br />

Isolation Of Low Molecular Weight Protein In Vitreous Humor Using A Protein<br />

Separator<br />

Haru Okamoto (National Tokyo Medical Center, JAPAN), Hiroyuki Shimada, Kiyoshi<br />

Matsuno, Kazuhiro Tanahashi, Jun Utsumi, Takeshi Iwata<br />

Withdrawn<br />

Withdrawn<br />

Unipep - A Resource For Targeted Biomarker Evaluation In Human Plasma And<br />

Tissue Samples<br />

Reto Ossola (Institute of Molecular Systemsbiology, SWITZERLAND), Johan<br />

Malmstroem, Dave Campbell, Kelly Cooke, Alexander Schmidt, Lars Malmstroem,<br />

Julian Watts, Ruedi Aebersold, Bruno Domon<br />

The Number, Composition, And Autoimmunity Of Circulating Microparticles In<br />

Rheumatoid Arthritis And Systemic Lupus Erythematosus<br />

Ole Østergaard (Statens Serum InsTitut, DENMARK), Christoffer T. Nielsen, Lone<br />

Troelsen, Martin R. Larsen, Søren Jacobsen, Niels Heegaard<br />

Identification Of Hsp 27 As Methylglyoxal Target In Colon Mucosa Of Ulcerative<br />

Colitis<br />

Tomoko Oya-Ito (Department of Medical Proteomics, Kyoto Prefectural University<br />

of Medicine, JAPAN), Yuji Naito, Tomohisa Takagi, Osamu Handa, Hirofumi Matsui,<br />

Toshikazu Yoshikawa<br />

Withdrawn<br />

Depot Specific Expressions Of Proliferation-Related Proteins In Bovine Satellite Cells<br />

Soo-Jin Park (National Institute of Animal Science, KOREA), Seulmina Kwon, Eun<br />

Jung Jang, Mi-Rim Park, Dong-Woon Kim, Seung-Gu Hong, Hyun-JeonG Lee<br />

Elevation Of Complement Component 3 In The Blood Of Autistic Patients<br />

Traci Pawlowski (Translational Genomics Research Institute (Tgen), UNITED<br />

STATES), April Allen, Jason Corneveaux, Jennifer Webster, Dietrich Stephan,<br />

Christopher Smith, Sarah Brautigam, Janet Kirwin, Matthew Huentelman<br />

Identifying Predictive Biomarkers Of Gastric Cancer Using Ms Profiling And 2-D Dige<br />

Megan Penno (Adelaide Proteomics Centre, University of Adelaide, AUSTRALIA),<br />

Matthias Ernst, Peter Hoffmann<br />

98 99


P-TUE-026<br />

P-TUE-027<br />

P-TUE-028<br />

P-TUE-029<br />

P-TUE-030<br />

P-TUE-031<br />

P-TUE-032<br />

P-TUE-033<br />

P-TUE-034<br />

P-TUE-035<br />

P-TUE-036<br />

P-TUE-037<br />

P-TUE-038<br />

P-TUE-039<br />

P-TUE-040<br />

Plasma Biomarker Discovery In Hepatocellular Carcinoma- A Pilot Case-Control<br />

Study In The Gambia<br />

Amelie Plymoth (International Agency for Research on Cancer, FRANCE), Pierre<br />

Hainaut, Laura Beretta<br />

Effects Of Organophosphates On Peptide Fraction Of Human Blood Serum<br />

Ekaterina Podolskaya (Institute for Analytical Instrumentation, Ras, RUSSIAN<br />

FEDERATION), Vladimir Babakov, Nikolay Goncharov, Lidia Glashkina, Elena Ermolaeva,<br />

Dariya Prokof’eva, Iliya Krasnov, Nikita Polyakov, Andrey RadiLov, Nikolay Krasnov<br />

Proteome Analysis Of Lung Squamous Cell Carcinoma Tissue Reveals Hsp47 And<br />

Cytokeratins As Potential Biomarkers<br />

Gereon Poschmann (Ruhr-Universität Bochum, GERMANY), Bence Sipos, Anna<br />

Ulrich, Christian Stefan, Bettina Warscheid, Guenther Kloeppel, Ann Vander Borght,<br />

Frans Ramaekers, Helmut E. Meyer, Kai Stuehler<br />

Potential Biomarkers For Early Detection Of Graft-Versus-Host Disease<br />

Alexandra Kaplanova, Ondrej Sedo, Hana Konecna, Sarka Pospisilova (Center of Molecular<br />

Biology and Gene Therapy, Department of Internal Medicine - Hematooncology, Medical<br />

Faculty Mu and University Hospital Brno, CZECH REPUBLIC), Jiri Mayer, Zbynek Zdrahal<br />

Characterization Of Ptms Of Ttr In Csf From Dementia Patients And Controls<br />

By Ia-Ms<br />

Keld Poulsen (Statens Serum Institut, DENMARK), Justyna Bahl, Martin Larsem,<br />

Niels Heegaard<br />

Sample Preparation For The Proteomic Analysis Of The Lung Biofluids<br />

Anne Puustinen (Finnish Institute of Occupational Health, FINLAND)<br />

Urine Peptidomics With Lc-Ms<br />

Suvi Ravela (Clinical Chemistry, University of Helsinki, FINLAND), Sakari Joenväärä,<br />

Risto Renkonen, Ulf-Håkan Stenman, Leena Valmu<br />

Plasma Protein Profiles In Early Asthmatic Responses To Inhalation Allergen Challenge<br />

Taiyoun Rhim (Soonchunhyang University Hospital, KOREA), Yun-Sung Choi, Bo-Young<br />

Nam, Soo Taek Uh, Jongsook Park, Yong Hoon Kim, Choon-Sik Park<br />

Study Of Protein Biomarker For Diabetes Type 2 In Local Population<br />

Samreen Riaz (Microbiology & Molecualr Genetics Dept, Punjab Univesrity, Lahore,<br />

PAKISTAN), Saadia Shahzad Alam, M Waheed Akhtar<br />

Identification Of Serum Candidate Biomarkers By 2-De And Maldi Tof/Tof Ms<br />

Maria Stella Ritorto (Fraunhofer Item, GERMANY), Juergen Borlak<br />

Secretome Analysis Of Human Primary Fibroblasts Undergoing Senescence<br />

Adelina Rogowska-Wrzesinska (University of Southern Denmark, DENMARK), Lucia<br />

Miciutkowa, Thomas Diener, Chen Li, Rong Zeng, Pidder Jansen-Dürr, Peter Roepstorff<br />

Correlation Of Proteomics And Clinical Data Of Patients With Chronic<br />

Lymphocytic Leukemia<br />

Jose Cesar Rosa (Fmrp - University of Sao Paulo, BRAZIL)<br />

Withdrawn<br />

Search For Multiple Sclerosis Proteomic Biomarkers In Cerebrospinal Fluid By<br />

Chiplc-Ms<br />

Therese Rosenling (University of Groningen, THE NETHERLANDS)<br />

Sensitive And Fast Hepcidin Quantitation From Crude Urine With Maldi Ms<br />

Udo Roth, Christoph Menzel (Qiagen GmbH, GERMANY), Christian Feckler, Kerstin Steinert<br />

C. Elegans And Drosophila<br />

P-TUE-041<br />

P-TUE-042<br />

P-TUE-043<br />

P-TUE-044<br />

P-TUE-045<br />

P-TUE-046<br />

P-TUE-047<br />

O-Linked N-Acetylglucosamine Modification Regulates Dauer Entry In<br />

Caenorhabditis Elegans<br />

Kwang Youl Kim (Department of Biochemistry, Yonsei University, KOREA), Jeeyong<br />

Lee, Jihyun Lee, Young-Ki Paik<br />

Withdrawn<br />

Identification Of Phosphorylcholine Substituted Proteins In Caenorhabditis Elegans<br />

Julia Grabitzki, Michael Ahrend, Rudolf Geyer, Guenter Lochnit (Institute of<br />

Biochemistry, University Giessen, GERMANY)<br />

Proteomic Studies Of Lepidoptera<br />

Susanne Preiss (Max Planck Institute for Chemical Ecology, GERMANY), Yannick<br />

Pauchet, Juliette Courtiade, David Heckel<br />

Comparative Functional Analysis Of The Caenorhabditis Elegans And Drosophila<br />

Melanogaster Proteomes<br />

Sabine Schrimpf (University of Zurich; Institute of Molecular Biology,<br />

SWITZERLAND), Manuel Weiss, Lukas Reiter, Christian Ahrens, Marko Jovanovic,<br />

Johan Malmström<br />

Withdrawn<br />

Pressure-Mediated Sample Preparation Methods For Isolating Proteins From<br />

Caenorhabditis Elegans<br />

Gary Smejkal (Pressure Biosciences, UNITED STATES), Jobriah Anderson, W Kelley<br />

Thomas, Ada Kwan, Greta Carlson, Vera Gross, Alexander Lazarev<br />

P-TUE-048 Involvement Of Nucleotidyl Transferases In Rnai And Germline Viability In C.<br />

Elegans<br />

Josien van Wolfswinkel (Utrecht University, Dept of Biomolecular Mass<br />

Spectrometry / Hubrecht Institute, Dept of Rna Silencing, THE NETHERLANDS),<br />

Jeroen Krijgsveld, Abby Dernburg, Albert Heck, Rene Ketting<br />

Cancer Related Signaling<br />

P-TUE-049<br />

P-TUE-050<br />

P-TUE-051<br />

P-TUE-052<br />

Modified Tumor Cell Protein Expression And Modification Under Physiological Oxygen<br />

Tamara Nyberg (Molecular Probes-Invitrogen, UNITED STATES), Kondala Atkuri,<br />

Courtenay Hart, Kurosh Ameri, Brian Agnew<br />

Differential Protein Expression In Activated E2f2-/- T Lymphocyte Non-Cytosolic<br />

Fraction<br />

Mikel Azkargorta (Department of Biochemistry and Molecular Biology, University of<br />

The Basque Country, SPAIN), Kerman Aloria, Ana Zubiaga, Jesus Mari Arizmendi,<br />

Asier Fullaondo<br />

Systemic Analysis Of Tgf β; Proteomics Revealed Involvement Of Plag1/Cnk1/<br />

Rassf1a/Src Network In Tgf β;1-Dependent Activation Of Erk1/2 And Cell<br />

Proliferation<br />

Nimesh Bhaskaran (Karolinska Biomics Center, Department of Oncology-Pathology,<br />

Karolinska Institutet, Karolinska University Hospital, SWEDEN), Serhiy Souchelnytskyi<br />

Detection Of Protein Signatures Associated With Tumor Cell Dissemination In<br />

Oral Cancer<br />

Onno Bleijerveld (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />

University, THE NETHERLANDS), Ruud Brakenhoff, Mirjam Damen, Maarten Altelaar,<br />

Albert Heck, Rene Leemans, Monique Slijper<br />

100 101


P-TUE-053<br />

P-TUE-054<br />

P-TUE-055<br />

Induction Of Apoptosis In Jeko-1 Mantle Cell Lymphoma Cell Line By Resveratrol:<br />

A Proteomic Analysis<br />

Daniela Cecconi (University of Verona, Dip. Scientifico e Tecnologico, Laboratorio di<br />

Proteomica, ITALY), Alberto Zamò, Alice Parisi, Elena Bianchi, Claudia Parolini, Anna<br />

Maria Timperio<br />

Differentially Expressed Phosphorylated Proteins In Gastrointestinal Stromal<br />

Tumors According To Kit And Pdgfra Mutation<br />

Hee-Jung Choi (Department of Pathology / Brain Korea 21 Project for Medical<br />

Sciences, Yonsei University College of Medicine, KOREA), Hyun Ju Kang, Hanna Lee,<br />

Yeong Hee Ahn, Jong Shin Yoo, Hoguen Kim<br />

Proteome Analysis Of Human Ovarian Cancer Cells To Identify Tubb3 Protein<br />

Complexes<br />

Lucia Cicchillitti (“John Paul Ii ” Centre for High Technology Research and Education<br />

in Biomedical Sciences, Catholic University, Campobasso, ITALY)<br />

P-TUE-065<br />

P-TUE-066<br />

P-TUE-067<br />

P-TUE-068<br />

Functional Proteomics: Bisphenol A Disrupts The Mammary Proteome<br />

Sarah Jenkins (University of Alabama at Birmingham, Department of Pharmacology<br />

& Toxicology, UNITED STATES), Nandini Raghuraman, Coral Lamartiniere<br />

Dynamics Of Protein Nitration In The Cell Cycle<br />

Min Jia (Karolinska Biomics Center, THE NETHERLANDS)<br />

Combining Formaldehyde-Based Affinity Enrichment And Global Silac To Study<br />

Cdc42 Activity<br />

Juergen Kast (University of British Columbia, CANADA), Brent W. Sutherland<br />

Non-Histone Nuclear Factor Hmgb1 Is Secreted Through The Nuclear Pkc-Δ<br />

Mediated Phosphorylation<br />

Hanna Lee, Hyun Ju Kang, Hee-Jung Choi, Yeong-Hee Ahn, Hoguen Kim (Department<br />

of Pathology / Brain Korea 21 Project for Medical Sciences, Yonsei University College<br />

of Medicine, KOREA)<br />

P-TUE-056<br />

P-TUE-057<br />

AnaLysis Of Trail Resistance In Human Melanoma Cells Using Dige<br />

Ben Crossett (University of Sydney, AUSTRALIA), Eva Yang, Xu Dong Zhang, Peter<br />

Hersey, Richard Christopherson<br />

Proteome Profiling Of Neuroblastoma Resistant Cell Line By 2de And Label-Free<br />

Lc-Ms<br />

Simona D’aguanno (Dipartimento di Medicina Interna Università di Tor Vergata Rome/<br />

Irccs-Fondazione Santa Lucia Centro di Ricerca Sul Cervello, ITALY), Annamaria<br />

D’alessandro, Luisa Pieroni, Sergio Bernardini, Giorgio Federici, Andrea Urbani<br />

P-TUE-069<br />

P-TUE-070<br />

Subnuclear Proteomics Through Differential Extraction Of Colorectal Cancer<br />

Tissue<br />

Jakob Albrethsen, Jaco Knol (Oncoproteomics Laboratory, VUmc-Cancer Center<br />

Amsterdam, THE NETHERLANDS), Sander Piersma, Meike de Wit, Sandra Mongera,<br />

Beatriz Carvalho, Gerrit Meijer, Connie Jimenez<br />

Interaction Of The Corepressor Alien With E2f/Rb Pathway<br />

Robert Kob (Institute of Human Genetics and Anthropology, GERMANY), Juliane<br />

Kelm, Aria Baniahmad, Ferdinand von Eggeling, Christian Melle<br />

P-TUE-058<br />

P-TUE-059<br />

P-TUE-060<br />

The Proteomic Analysis Of B Cell Signaling In Chronic Lymphocytic Leukaemia<br />

Gina Eagle (Cancer Biology Proteomics Group, Post Graduate Medical Institute<br />

of the University of Hull in Association with the Hull York Medical School, UNITED<br />

KINGDOM), David Allsup, Lynn Cawkwell<br />

New Functions Of P16ink4a Using A Proteomic Approach<br />

Josep M. Estanyol (University Of Barcelona, SPAIN)<br />

Protein And Peptide Profiling Of Fresh Human Breast Cancer Tumours<br />

Christina Greenwood (Helen RollaSon Heal Cancer Research Laboratory, Anglia<br />

Ruskin University, UNITED KINGDOM), Gergana Metodieva, Louise Alldridge, Laura<br />

Thwaites, Khalid Al-Janabi, Metodi Metodiev<br />

P-TUE-071<br />

P-TUE-072<br />

P-TUE-073<br />

Human Prostate Cancer Progression: A Complete Proteomic Analysis<br />

John Lapek (Proteomics Center, University of Rochester, UNITED STATES), Lauren<br />

Jensen, William Ricke, Alan Friedman<br />

Use Of Peptide Ief-Lc-Ms/Ms Reveals Proteome Components Involved In Lung<br />

Cancer Therapy Response<br />

Janne Lehtiö (Karolinska Institutet, SWEDEN), Lukas Orre, Johan Lengqvist, Hanna<br />

Eriksson, Bengt Persson, Per-Johan Jakobsson, Rolf Lewensohn<br />

Proteomics Approaches For Studying Molecular Mechanism Of Invasion Of Highly<br />

Invasive Clones Of Mcf-7 Human Breast Carcinoma<br />

Kah-Wai Lin (Karolinska Biomics Center, SWEDEN), Serhiy Souchelnytskyi<br />

P-TUE-061<br />

P-TUE-062<br />

P-TUE-063<br />

P-TUE-064<br />

Whole-Celss Proteome Analysis Of The Mtor Signaling Using 2d Digest-Lc-Ms/<br />

Ms And Index-T<br />

Sang Hoon Ha (Sigmol Inc., KOREA), Yoen-Young Yoo, Pann-Ghill Suh, Sung Ho Ryu,<br />

Taehoon Lee<br />

Target Proteins Of Lps-Stimulated Lipid Accumulation Regulated By Thiol-<br />

Antioxidant Thioredoxin<br />

Gi-Yeon Han (Korea University, KOREA), Eun-KYung Lee, Hye-Won Park, Hyun-Ji Lee,<br />

Eun-Jeong So, Won-A Joo, Yoon-Ha Kim, Jun-Seop Shin, Mi-Ryung Kim, Chan-Wha<br />

Kim<br />

Effects Of Microenvironment On Tumor Growth: A Comparative Proteomics<br />

Approach<br />

Sen-Yung Hsieh (Chang Gung Memorial Hospital, TAIWAN), Ying-Chin Chen<br />

Metastasis-Associated C4.4a, A Gpi-Anchored Protein Cleaved By Adam10 And<br />

Adam17<br />

Cary Esselens, Jordi Malapeira, Nuria Colome, Joaquin Arribas, Francesc Canals,<br />

Wolfgang Jabs (Bruker Daltonik GmbH, GERMANY), Detlev Suckau, Carsten<br />

Baessmann<br />

P-TUE-074<br />

P-TUE-075<br />

P-TUE-076<br />

P-TUE-077<br />

Discovery Of Pra1-Associated Dysregulated Proteins By Itraq And<br />

Multidimensional Lc-Ms/Ms<br />

Hao-Ping Liu (Institute of Basic Medical Science, Chang Gung University, TAIWAN)<br />

Exploration Of The Cathepsin D Protein Complexes In Senescent Pathways<br />

Xiaomin Lou (Beijing Genomics Institute, Chinese Academy of Sciences / Beijing<br />

Proteomics Institute, CHINA), Ju Zhang, Maomao Sun, Siqi Liu, Ningzhi Xu<br />

Down-Regulation Of Ptk6 In Breast Cancer Cell Lines For Identification Of Novel<br />

Therapy Targets<br />

Natalie Ludyga (Helmholtz Zentrum München - German Research Center for<br />

Environmental Health, GERMANY), Manuela Ram, Natasa Anastasov, Ulrike Reich,<br />

Heinz Höfler, Michaela Aubele<br />

Identification Of Proteins Targeted By Apc/C-Cdh1 During Mitosis Exit By Silac<br />

Jose L. Luque-Garcia (Protein Technology Unit. Spanish National Cancer Research<br />

Center (Cnio), SPAIN), Eusebio Manchado, Marcos Malumbres, Ignacio Casal<br />

102 103


P-TUE-078<br />

P-TUE-079<br />

P-TUE-080<br />

P-TUE-081<br />

P-TUE-082<br />

P-TUE-083<br />

P-TUE-084<br />

P-TUE-085<br />

P-TUE-086<br />

P-TUE-087<br />

P-TUE-088<br />

P-TUE-089<br />

Proteome And Phosphoproteome Dynamics In Human Cells Upon Inhibition Of<br />

Hsp90<br />

Boris Macek (Mpi for Biochemistry, Dept. of ProteoMics and Signal Transduction,<br />

GERMANY), Martin Vabulas, Chanchal Kumar, Florian Gnad, Ulrich Hartl, Matthias<br />

Mann<br />

Proteomic Analysis Of The Interacting Partners Of The Spindle Checkpoint<br />

Protein Bub3<br />

Alessio Maiolica (European Institute of Oncology Ieo, ITALY), Silvia Monzani, Paolo<br />

Soffientini, Andrea Musacchio<br />

Far Upstream Element Binding Protein-1, A C-Myc Transcription Factor, Is<br />

Cleaved By Caspases During Apoptosis<br />

Jang Mi (KOREA)<br />

Proteomic Analysis Of TransforminG Growth Factor Beta Signaling In Colon<br />

Cancer Cells<br />

Naveid Ali, Karlie Nielson, Mark Molloy (Macquarie University, AUSTRALIA)<br />

Withdrawn<br />

Indoor Air Exposure Of Volatile Organic Compounds On Human Alveolar Cells<br />

Nora Mörbt (Department of Proteomics, Helmholtz-Centre for Environmental<br />

Research, GERMANY), Frank Schmidt, Ralph Feltens, Carmen Röder-Stolinski,<br />

Gundula Fischäder, Irina Lehmann, Martin Von Bergen<br />

Complex Formation Between S100a11 And Rad54b At Dna Damage Sites<br />

Ulrike Murzik (Institute of Human Genetics and Anthropology, Medical Faculty,<br />

Friedrich-Schiller-University, GERMANY), Peter Hemmerich, Juliane Jung, Ferdinand<br />

von Eggeling, Christian Melle<br />

Proteomics Of Pcna: Cell Transformation Is Accompanied By Up-Regulation Of<br />

Pcna Without Post-Translational Modifications<br />

Stanislav Naryzhny (Hrsrh, CANADA), Hoyun Lee<br />

Label-Free Proteome Profiling Of Archival Childhood Brainstem Tumors<br />

Javad Nazarian (Children’s National Medical Center, UNITED STATES), Brian Halligan,<br />

Mariarita Santi, Tobey Macdonald, Yetrib Hathout<br />

Novel Functional Approach Combining Reverse Phase Protein Micorarrays<br />

(Rpma) And 3d Ex-Vivo Tissue Cultures: Expression Analysis Of Apoptosis-<br />

Related Proteins In Human Colon Cancer And Response To Chemotherapeutic<br />

Treatment<br />

Michael Pawlak (Nmi Natural and Medical Sciences Institute, GERMANY), Gerhard<br />

G. Thallinger, Markus F. Templin, Markus Borner<br />

Secreted Proteins Of Malignant Breast Cells Coordinate Angiogenesis Through<br />

Ecm Degradation<br />

Xiquan Liang, Jarkko Huuskonen, Mahbod Hajivandi, Paul Predki, Marshall Pope<br />

(Invitrogen, UNITED STATES)<br />

Protein Expression Analysis By 2d-Dige Of Different Areas Of Gbm From<br />

Patient Biopsies<br />

Roberto Raggiaschi (Siena Biotech S.P.A., ITALY), Silvia Matteoni, Annunziato<br />

Mangiola, Letizia Magnoni, Stefano Gotta, Andreas Kremer, Marco Rossi, Silvia<br />

Valensin, Annette Bakker<br />

P-TUE-090<br />

P-TUE-091<br />

P-TUE-092<br />

P-TUE-093<br />

P-TUE-094<br />

P-TUE-095<br />

P-TUE-096<br />

P-TUE-097<br />

P-TUE-098<br />

P-TUE-099<br />

P-TUE-100<br />

Search For Markers Predicting The Cisplatin Chemosensitivity In Large-Cell<br />

Neuroendocrine Carcinoma<br />

Yuichi Sato (Department of Molecular Diagnostics, Kitasato University School of Allied<br />

Healh Scinences / Department f Molecular Diagnostics, Kitasato University Graduate<br />

School of Medical Siences / Center for Disease Proteomics, Kitasato University<br />

School of Science, JAPAN), Taihei Kageyama, Ryo Nagashio, Toshihide Tatsumoto,<br />

Mihoko Ohnishi, Yoshio Kodera, Tadakazu Maeda, Shi-Xu Jiang, Isao Okayasu<br />

Macrophage-Differentiating Factors Of Cancer Cell Lines Studied By Secretome<br />

Profiling<br />

Silvia Schiarea (Istituto di Ricerche Farmacologiche Mario Negri, ITALY), Paola<br />

Allavena, Graziella Solinas, Roberto Fanelli, Chiara Chiabrando<br />

Spink3 Is An Indicator Of Erbeta Negative, Poorly Differentiated Prostatic<br />

Epithelium<br />

Thomas Schwend (Karolinska Institute, SWEDEN), Otabek Imamov, Thomas Ruppert,<br />

Linda Waage, Ulf Bergerheim, Jan-Ãke Gustafsson<br />

From Proteomics To Molecular Targets For Elimination Of Apoptosis-Resistant<br />

Leukemic Cells<br />

Tereza Simonova (Department Of Pathophysiology, First Faculty Of Medicine, Charles<br />

University, CZECH REPUBLIC), Ondrej Toman, Petr Halada, Pavel Klener, Jan Zivny,<br />

Jiri Petrak<br />

Identification Of Holliday Junction (Hj) Processing Enzymes In Human Cells<br />

J Mark Skehel (Cancer Research Uk, UNITED KINGDOM), Stephen Ip, Helen Flynn,<br />

Simon Swindell, Mark Pitman, Stephen West<br />

Proteomics Of Breast Cancer: Systemic Analysis Of Various Datasets To Identify<br />

Markers And Drug Targets<br />

Serhiy Souchelnytskyi (Karolinska Biomics Center, SWEDEN)<br />

Quantitative Proteome And Phosphoproteome Analysis Of Fasl/Trail-Induced<br />

Apoptosis<br />

Gabriele Stoehr (Department of Proteomics and Signal Transduction, Max Planck<br />

Institute for Biochemistry, GERMANY), Chunaram Choudhary, Boris Macek,<br />

Matthias Mann<br />

Identification Of P53 Interacting Proteins In Nasopharyngeal Carcinoma Cells By<br />

Proteomics Analysis<br />

Yi Sun (Key Laboratory of Cancer Proteomics of Chinese Ministry of Health,<br />

Xiangya Hospital / Cancer Research Institute, Xiangya School of Medicine / Human<br />

Reproductive and Stem Cell Engineering Institute, CHINA), Zhi-Qiang Xiao, Zhu-Chu<br />

Chen, Mao-Yu Li<br />

Tissue Transglutaminase 2 Could Be A Novel Candidate Of Hepatocellular Carcinoma<br />

Yilin Sun (State Key Labotatory of Molecular Oncology, Cancer Institute & Hospital,<br />

Chinese Academy of Medical Sciences, CHINA), Wei Mi, Jianqiang Cai, Wantao Ying,<br />

Fang Liu, Lei Li, Wei Jia, Lanping Zhou, Xinyu Bi, Haizhen Lu<br />

Escape Mechanisms In Metronomic Cyclophosphamide Therapy In Vivo<br />

Lilja Thoenes (Lmu Munich, GERMANY), Michael Guenther, Manfred Ogris, Georg J.<br />

Arnold, Ernst Wagner<br />

Silencing Bcl-2 In Mantle Cell Lymphoma<br />

Catherine Tucker (Department of Advanced Therapeutics / DepartMent of Pathology<br />

and Laboratory Medicine, CANADA), Anita Kapanen, Ghania Chikh, Brad Hoffman,<br />

Alastair Kyle, Ian Wilson, Dana Masin, Randy Gascoyne, Marcel Bally, Richard Klasa<br />

104 105


P-TUE-101<br />

P-TUE-102<br />

Characterisation Of Signal Transduction Complexes Associated With The C-Kit<br />

Receptor<br />

Jurjen van Bolhuis (Erasmus University Mc, THE NETHERLANDS)<br />

Proteomic Profiling Of Glioblastoma Cells Following mir-21 Knockdown<br />

Matthew Willetts (Applied Biosystems, UNITED STATES), Marjorie Minkoff, Thales<br />

Papagiannakopoulos, Kenneth Kosik, Phil Ross, Darryl Pappin<br />

Chemical Proteomics<br />

P-TUE-111<br />

Selectivity In Enrichment Of Pka And Their Interactors Using Modified Affinity<br />

Resins And Chemical Proteomics<br />

Thin Thin Aye (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />

University; Department of Medical Physiology, University Medical Centre, THE<br />

NETHERLANDS)<br />

P-TUE-103<br />

Ca11, An Autocrine Protein In Gastric Epithelium, Plays A Role In Regulation Of<br />

Cell Cycle<br />

Rui Xing (Beijing Genomics Institute, Cas, CHINA), Jun Zhang, Bin Kang, Siqi Liu,<br />

Youyong Lu<br />

P-TUE-112<br />

A Chemical Proteomics Approach For Assessing Target Selectivity Of Kinase<br />

Inhibitors<br />

Marcus Bantscheff (Cellzome Ag, GERMANY), Dirk Eberhard, Friedrich Reinhard,<br />

Carsten Hopf, Ulrich Kruse, Bernhard Kuster, Gerard Drewes<br />

P-TUE-104<br />

P-TUE-105<br />

Phosphorylation Of Eef1a1 By Tgf-Beta Receptor<br />

Ihor Yakymovych (Karolinska Biomics Center, Department of Oncology-Pathology,<br />

Karolinska University Hospital, SWEDEN), Mariya Yakymovych, Serhiy Souchelnytskyi<br />

Cross-Link Of Proteome With Transcriptome For Metastasis Hcc<br />

Pengyuan Yang (Institutes for Biomedical Sciences and Research Institute for Liver<br />

Cancer, Fudan Uni Shanghai, CHINA)<br />

P-TUE-113<br />

P-TUE-114<br />

Fast Enzymatic Protein Digestion: Microwave Versus Ultrasonication<br />

Jose-Luis Capelo-Martínez (New University of Lisbon, Portugal)<br />

Proteomics Of Stressed Chondrocytes To UndersTand Mechanisms Of Skeletal<br />

Dysplasia<br />

Wai Ling Chan (The University of Hong Kong, CHINA), Danny Chan, Stephen Lee, Kse<br />

Cheah, Julian A. Tanner<br />

P-TUE-106<br />

P-TUE-107<br />

Proteomics Analysis Of Anti-Cancer Activity Of Luteolin In Human Hepatoma<br />

Huh-7 Cells<br />

Dong-Ryeol Yoo (Gachon University of Medicine and Science, KOREA), Young-Keul<br />

Jeon, Yun-Ho Jang, Dong-Jin Yim, Ju-Yeon Kim, Won Jeon, Chae-Jun Lim, Myeong-Jin<br />

Nam<br />

Proteome Profiling Of Human Breast Cancer (Case Studies)<br />

Olena Zakharchenko (Karolinska BIomics Center, SWEDEN)<br />

P-TUE-115<br />

P-TUE-116<br />

Fluorescein As A Versatile Tag For Enhanced Selectivity In Analyzing Cysteine-<br />

Containing Proteins/Peptides Using Mass Spectrometry<br />

Shu-Hui Chen, Jue-Liang Hsu, Fong-Sian Lin, Pai-Chiao Cheng (Department of<br />

Chemistry, National Cheng Kung University, TAIWAN)<br />

Modified Au Nanoparticles For Resolving Protein Complexes Related To Estrogen<br />

Action<br />

Pai-Chiao Cheng (National Cheng Kung University, TAIWAN)<br />

P-TUE-108<br />

P-TUE-109<br />

P-TUE-110<br />

Mapping The Melanoma Phosphoproteome By High Resolution Mass<br />

Spectrometry<br />

Sara Zanivan (Max-Planck Institute for Biochemistry, Dept of Proteomics and Signal<br />

Transduction, GERMANY), Sara Wickström, Tami Geiger, Juergen Cox, Florian Gnad,<br />

Boris Macek, Reinhard Fässler, Matthias Mann<br />

Exploring The Functions Of Bag2 Complexes In Cell Senescence<br />

Ju Zhang (Beijing Genomics Institute, Chinese Academy of Science / Beijing<br />

Proteomics Institute, CHINA), Xiaomin Lou, ShanGbin Yang, Siqi Liu, Ningzhi Xu<br />

The Interaction Of Mawbp/Mawd Is Likely Involved In Tgf-Beta Signaling<br />

Pathway<br />

Jun Zhang (Beijing Genomics Institute, Chinese Academy of Sciences / Beijing<br />

Proteomics Institute, CHINA), Bin Kang, Rui Xing, Ningzhi Xu, Siqi Liu, Youyong Lu<br />

P-TUE-117<br />

P-TUE-118<br />

P-TUE-1<strong>19</strong><br />

P-TUE-120<br />

Withdrawn<br />

Assessing Dynamic Change Of Protein S-Nitrosylation By Label-Free<br />

Quantitative Proteomics<br />

Hsiao-Chiao Chou (Department of Chemistry, National Taiwan University, TAIWAN),<br />

Yi-Ju Chen, Wei-Chi Ku, Yu-Ju Chen<br />

Using Chemical Proteomics And Peptide Disrupters Technology To Evaluate Ri<br />

And Rii Specific Akaps<br />

Alessandro Cuomo (Ceinge Biotecnologie Avanzate, °S.E.M.M. -European School of<br />

Molecular Medicine, ITALY)<br />

Quantitative Chemical Proteomics: A Tool For Investigating (Off-) Target Binding<br />

Poupak Dadvar (Utrecht Institute for Pharmaceutical Sciences, THE<br />

NETHERLANDS), Arjen Scholten, Shabaz Mohammed, Bas Breukelen, Klaus Rumpel,<br />

Albert Heck<br />

P-TUE-121<br />

Functionality Directed Reduction Of Proteome Complexity<br />

Christian Dalhoff (Caprotec Bioanalytics GmbH, GERMANY), Peter Poot, Michael<br />

Hüben, Thomas Lenz, Christian Jurinke, Elmar Weinhold, Hubert Köster<br />

P-TUE-122<br />

Chemical Proteomics Strategy Reports On Proteasome Activity In Living Cells<br />

Bogdan (Bobby) Florea (Dept of Bio-Organic Chemistry, Leiden Institute of<br />

Chemistry, Leiden University, THE NETHERLANDS)<br />

P-TUE-123<br />

The Two Phase Partitioning System For Purification Of C. Glutamicum Membrane<br />

Proteins<br />

Benjamin Fränzel, Dirk Wolters (Analytical Chemistry, Ruhr University Bochum,<br />

GERMANY)<br />

106 107


P-TUE-124<br />

Functionalized Succinylhydroxamate Peptide Inhibitors For Activity-Based<br />

Enrichment Of Mmps/Adams<br />

Paul Geurink (Leiden University, THE NETHERLANDS), Theo Klein, Gijs van der Marel,<br />

Rainer Bischoff, Herman Overkleeft<br />

Computational Approaches To Mine Proteomic Data<br />

P-TUE-136<br />

Systems Biology For Compound And Protein Classification, And Interaction Mapping<br />

Ken Aoshima (Eisai Co., Ltd., JAPAN), Yoshiya Oda, Yuji Miura, Masumi Takahashi<br />

P-TUE-125<br />

P-TUE-126<br />

P-TUE-127<br />

P-TUE-128<br />

P-TUE-129<br />

Withdrawn<br />

Affinity Pull-Down Of Metalloproteases From Arabidopsis Thaliana<br />

Janina Lenger (Bioorganic Chemistry, Department of Chemistry, Bielefeld University,<br />

GERMANY), Jens Conradi, Hannes Patrik Plattner, Karl-Josef Dietz, Norbert Sewald<br />

Detection Of Galectin-3 By The Use Of Chemical Probes<br />

Monique van Scherpenzeel (Uu, THE NETHERLANDS), Rob M.J. Liskamp, Roland J.<br />

Pieters<br />

Ultrasonic Assisted Enzymatic Protein Digestion Kinetic Studies<br />

Carlos Lodeiro (Requimte- Chemistry Department, Faculty of Science and<br />

Technology, University Nova of Lisbon, Monte de Caparica, Portugal), Diana V. Vieira,<br />

Hugo M. Santos, Issa Isaac, José Luis Capelo<br />

Protein Kinase C Microarray Profiling To Design Isozyme Selective Inhibitors<br />

Alex J. Poot (Utrecht University, THE NETHERLANDS), Jeroen Ameijde, Rob<br />

Ruijtenbeek, Riet Hilhorst, Monique Slijper, Dirk T.S. Rijkers, Rob M.J. Liskamp<br />

P-TUE-137<br />

P-TUE-138<br />

P-TUE-139<br />

P-TUE-140<br />

Postman, A New Tool For Comparative Lc-Ms In Ptm Detection<br />

Magnus Arntzen (Probe Proteomic Unit, Department of Biomedicine, University of<br />

Bergen, NORWAY), Christoffer Osland, Christopher Raa, Maria Ekman, Burkhard<br />

Fleckenstein, Aurelia Lewis, Clive Dsantos<br />

Of Planets And Portability: A Common Api For Desktop Proteomics Data Analysis<br />

Manor Askenazi (Dana-Farber Cancer Institute, UNITED STATES), Jignesh Parikh,<br />

Tanya Cashorali, Scott Ficarro, Yi Zhang, Nathaniel Blank, Jarrod Marto<br />

Close Correlations Between Transcript And Proteome Expression Of Gene-<br />

Protein Pairs Across Heart- And Skeletal Muscle<br />

Emøke Bendixen (University of Århus, DENMARK), Frank Panitz, Henrik Hornshøj,<br />

Lene Conley, Pernille Andersen, Jakob Hedegaard, Christian Bendixen<br />

Increase Identification Rate By Combining On-The-Fly Spectral Library And<br />

Sequence Searches<br />

Erik Ahrne, Markus Müller, Pierre-Alain Binz, Alexandre Masselot, Frederique Lisacek<br />

(Swiss Institute of Bioinformatics, Proteome Informatics Group, SWITZERLAND)<br />

P-TUE-130<br />

P-TUE-131<br />

Proteomic Analysis Of Macrophages Stimulated By Lipopolysaccharide And<br />

Treated With Celecoxib As Selective Cox-2 Inhibitor<br />

Mona Salimi (Research & Development Center, Pasteur Institute of Iran, Karaj,<br />

IRAN), Faegheh Rezaee, Soudabeh Akbarzadeh, Mohammad Hossein Ghahremani,<br />

Behrouz Vaziri<br />

Desalting Free Ultrasonic-BaSed Method For Protein Identification By Pmf<br />

Hugo Miguel Santos (Requimte - Chemistry Department Fct-Unl, PORTUGAL),<br />

Cristiano Mota, Isabel Moura, Carlos Lodeiro, Issa Isaac, José-Luis Capelo<br />

P-TUE-141<br />

P-TUE-142<br />

On The Stability Of Peptide Identifications When Looking At Variations In<br />

Ms/Ms Spectra<br />

Markus Müller, Pierre-Alain Binz, David Bouyssié, Frederique Lisacek, Olivier Philippe<br />

(Geneva Bioinformatics (Genebio), SWITZERLAND)<br />

Classification Using A 1d Representation Of Lc-Ms Data<br />

Tom Bloemberg (Analytical Chemistry - Institute for Molecules and Materials -<br />

Radboud University Nijmegen, THE NETHERLANDS), Jolein Gloerich, Hans Wessels,<br />

Wendy Pluk, Ron Wehrens, Lambert van den Heuvel, Lutgarde Buydens<br />

P-TUE-132<br />

Paired Stable Isotope Metabolic Tracers: A Novel Approach For Discovery Of<br />

Drug Metabolites<br />

Nicolas A.S. Stewart (University of Pittsburgh, UNITED STATES), Jennifer N.<br />

Sutton, Brian L. Hood, Raman Venkataramanan, Michael Athanas, Robert A. Branch,<br />

Thomas P. Conrads<br />

P-TUE-143<br />

Icplquant - A New Software Tool For Isotope-Labelling Based Proteomics And<br />

Biomarker Discovery<br />

Achim Brunner (Max-Planck Institute of Biochemistry, Martinsried, GERMANY),<br />

Eva-Maria Keidel, Monica Zobawa, Silke Martin, Michael Kersten, Josef Kellermann,<br />

Friedrich Lottspeich<br />

P-TUE-133<br />

P-TUE-134<br />

P-TUE-135<br />

Probing Proteasome Regulation<br />

Wouter van der Linden (Biosyn Leiden University, THE NETHERLANDS), Martijn<br />

Verdoes, Bobby Florea, Gijsbert van der Marel, Herman Overkleeft<br />

Chemical Tools To Probe The Proteasome<br />

Martijn Verdoes (Bioorganic Synthesis, Leiden Institute of Chemistry, THE<br />

NETHERLANDS), Bogdan Florea, Ulrik Hillaert, Wouter van der Linden, Lianne<br />

Willems, Myra Sae-Heng, Gijsbert van der Marel, Herman Overkleeft<br />

The Synthesis And Biological Evaluation Of Peptide N-Glycanase Inhibitors<br />

Martin D. Witte (Bioorganic Synthesis, Leiden Institute of Chemistry, THE<br />

NETHERLANDS), Bogdan I. Florea, Gijsbert van der Marel, Herman S. Overkleeft<br />

P-TUE-144<br />

P-TUE-145<br />

P-TUE-146<br />

P-TUE-147<br />

Withdrawn<br />

The Gene Ontology Annotation (Goa) Project At The Ebi<br />

Emily Dimmer (European Bioinformatics Institute, UNITED KINGDOM), Rachael<br />

Huntley, Daniel Barrell, David Binns, Claire O’Donovan, Rolf Apweiler<br />

Identification And Quantification Of Endogenous Peptides In A Model Of<br />

Parkinson’s Disease<br />

Maria Falth (Uppsala University, SWEDEN), Anna Nilsson, Kim Kultima, David Fenyö,<br />

Per Svenningsson, Per Andren<br />

On The Peptide Fragment Mass Information Required To Identify Peptides<br />

David Fenyo (The Rockefeller University, UNITED STATES), Elena Ossipova, Jan Eriksson<br />

P-TUE-148<br />

Keynode AnaylysiS ¡V Method To Identify Potential Biomarkers For Dominant<br />

Signaling Pathways<br />

Yi Man Eva Fung (Division of Molecular Biometry, Institute for Cell and Molecular Biology,<br />

Uppsala University, SWEDEN), Roman A. Zubarev, Peter Bergsten, Hanna Nyblom<br />

108 109


P-TUE-149<br />

Machine Learning-Based Membrane Protein Identification<br />

Tejas Gandhi (Membrane Enzymology Group / Groningen Bioinformatics Center,<br />

University of Groningen, THE NETHERLANDS), Bert Poolman, Hjalmar Permentier,<br />

Rainer Brietling<br />

P-TUE-162<br />

Probability Assignment And Protein Inference For Accurate Mass And Time<br />

Analysis<br />

Damon May (Fred Hutchinson Cancer Research Center, UNITED STATES), Yan Liu,<br />

Wendy Law, Martin Mcintosh<br />

P-TUE-150<br />

P-TUE-151<br />

P-TUE-152<br />

P-TUE-153<br />

Withdrawn<br />

Peptizer: A Rule-Based Bioinformatics Tool To Select Suspicious Peptide<br />

Identifications<br />

Kenny Helsens (Department of Medical Protein Research/ Department of<br />

Biochemistry, Ghent University, BELGIUM), Evy Timmerman, Joël Vandekerckhove,<br />

Kris Gevaert, Lennart Martens<br />

A Machine Learning Approach For Ranking Of Proteotypic Peptides For Ms<br />

Carsten Henneges (Wilhelm-Schickard-Institute / Computerarchitecture,<br />

GERMANY), Georg Hinselmann, Johannes Madlung, Stephan Jung, Tobias<br />

Lamkemeyer, Alfred Nordheim, Andreas Zell<br />

Withdrawn<br />

P-TUE-163<br />

P-TUE-164<br />

P-TUE-165<br />

New Developments For Open-Source Shotgun Proteomics Analysis With The<br />

Trans-Proteomic Pipeline<br />

Luis Mendoza (Institute for Systems Biology, UNITED STATES), Joshua Tasman,<br />

David Shteynberg, James Eddes, Brian Pratt, Eric Deutsch, Chee-Hong Wong,<br />

Henry Lam, Jimmy Eng, Ruedi Aebersold<br />

Identifying Unexpected Modifications Using Accurate Mass Ms And A New<br />

Search Algorithm<br />

Christine A. Miller (Agilent Technologies, UNITED STATES), David M. Horn, Joseph C. Roark<br />

Analysis Of Peak Intensity Correlations To Improve Diagnostic Accuracy And Maximize<br />

Biological Meaning Of Mass-Spectral Diagnostics Of Ovarian And Prostate Cancer<br />

Sergey Moshkovskiy (Institute of Biomedical Chemistry Rams, RUSSIAN FEDERATION),<br />

M Vlasova, M Pyatnitsky, I ToropygIn, A Archakov<br />

P-TUE-154<br />

P-TUE-155<br />

P-TUE-156<br />

P-TUE-157<br />

P-TUE-158<br />

P-TUE-159<br />

P-TUE-160<br />

P-TUE-161<br />

Proteomedigger: A Versatile Disease Proteome Database And Analysis Platform<br />

For The Discovery Of Plasma-Localized Cancer Biomarkers.<br />

Seul-Ki Jeong (Department of Biochemistry, Yonsei Proteome Research Center and<br />

Biomedical Proteome Research Center, KOREA), Min-Seok Kwon, Eun-Young Lee,<br />

Sang Yun Cho, Hoguen Kim, Gilbert S. Omenn, Ruedi Aebersold, Young-Ki Paik<br />

Calculation Of Unique Peptide Sequences For Unambiguous Identification Of<br />

Highly Homologous Proteins<br />

Michael Kohl (Medizinisches Proteom Center, GERMANY), Gorden Redlich, Martin<br />

Eisenacher, Anke Schnabel, Katrin Marcus, Helmut E. Meyer, Christian Stephan<br />

Consensus Predictors For Peptide Detectability<br />

King Wai Lau (Faculty of Life Sciences, University of Manchester, UNITED<br />

KINGDOM), Claire Eyers, David Wedge, Simon Gaskell, Simon J Hubbard<br />

Pnmerge: A Novel Cytoscape Plugin To Merge The Biological Pathway And<br />

Protein Networks<br />

Hanchang Sun, Dong Li (The State Key Laboratory of Proteomics, Beijing Proteome<br />

Research Center, Beijing Institute of Radiation Medicine, CHINA), Jian Wang,<br />

Hongwei Xie, Yunping Zhu, Fuchu He<br />

Comparative Analysis Of Various Parsimony Methods And Its Influence Factors<br />

For Protein Inference In Shotgun Proteomics<br />

Ning Li (State Key Laboratory of Proteomics, Beijing Proteome Research Center,<br />

Beijing Institute of Radiation Medicine, CHINA), Songfeng Wu, Yunping Zhu, Fuchu He<br />

A Missing Piece In Proteomics Identification Task: The Protein Family Tree<br />

Michal Linial (The Hebrew University of Jerusalem, Israel), Menachem Fromer,<br />

Solange Karsenty, Yaniv Loewenstein<br />

X!Tandem Powered By Cell Be Processor Runs 10-Times Faster Than The Same<br />

On A Pc<br />

Yaroslav Lyurvinskiy (Institut for Analytical Instrumentation, RUSSIAN<br />

FEDERATION), Sergej Fironov, Nikolay Krasnov<br />

Conservation And Stoichiometry Of The Human Mitotic Spindle Phosphoproteome<br />

Rainer Malik (Max Planck Institute for Biochemistry, Department of Cell Biology,<br />

GERMANY), Erich A. Nigg, Roman Körner<br />

P-TUE-166<br />

P-TUE-167<br />

P-TUE-168<br />

P-TUE-169<br />

P-TUE-170<br />

P-TUE-171<br />

P-TUE-172<br />

P-TUE-173<br />

P-TUE-174<br />

Assessing Significance Of Protein-Protein Interactions Using Spectral Counts<br />

Hyungwon Choi, Ashton Breitkreutz, Brett G. Larsen, Zhaohui S. Qin, Anne-Claude<br />

Gingras, Mike Tyers, Alexey I. Nesvizhskii (University of Michigan, Department of<br />

Pathology, UNITED STATES)<br />

Software Tools For The Analysis Of Quantitative Proteomics Data<br />

Lars Nilse (Manchester University, UNITED KINGDOM)<br />

Comparative Proteomic Phenotyping To Assess Preservation Of Cell Functions<br />

Cuiping Pan (Max-Planck Institute for Biochemistry, GERMANY), Chanchal Kumar,<br />

Sebastian Bohl, Ursula Klingmueller, Matthias Mann<br />

Identification Of Low Quality Peptide Ms/Ms Spectra Using Dominant<br />

Fragmentation Patterns<br />

Hjalmar Permentier (University of Groningen, THE NETHERLANDS), Elena Wiederhold,<br />

Bert Poolman<br />

The Same Proteins Again? A Hit Parade Of Differentially Expressed Proteins<br />

Repeatedly Identified By 2-De<br />

Jiri Petrak (Institute of Hematology and Blood Transfusion / Department of<br />

Pathophysiology, First Faculty of Medicine, Charles University, CZECH REPUBLIC),<br />

Robert Ivanek, Ondrej Toman, Daniel Vyoral, Jan Zivny, Christopher Vulpe<br />

Intensity-Based Differential Analysis Of Complex Protein Mixtures Using Two-<br />

Dimensional (2dlc and Gelc) Datasets Coupled To Ms/Ms<br />

Thang Pham (Vu University Medical Center, THE NETHERLANDS), Sander Piersma,<br />

Connie Jimenez<br />

Automated Meta-Analysis Confirms The Hit-Parade Of Repeatedly Identified Proteins<br />

Elena Ponomarenko (Institute of Biomedical Chemistry Rams, RUSSIAN FEDERATION),<br />

A Lisitsa, J Petrak, S Moshkovskiy, A Archakov<br />

Evaluation Of Efficiency Of Cross-Species Comparisons<br />

Derek Potter (Proxeon A/S, DENMARK), Hans Jespersen, Alexandre Podtelejnikov,<br />

Morten Bern<br />

Analysis Workflows To Mine Mass Spectrometry Data<br />

Andreas Quandt (Swiss Institute of Bioinformatics, SWITZERLAND), Patricia<br />

Hernandez, Alexandre Masselot, Celine Hernandez, Sergio Maffioletti, Cesare<br />

Pautasso, Ron D. Appel, Frederique Lisacek<br />

110 111


P-TUE-175 Nist Reference Libraries Of Peptide Fragmentation Spectra: 2008<br />

Paul Rudnick (Nist, UNITED STATES), Niksa Blonder, Yuri Mirokhin, Lewis Geer,<br />

Dmitrii Tchekhovskoi, Lisa Kilpatrick, Jeri Roth, Qian Dong, Stephen Stein<br />

P-TUE-176<br />

P-TUE-177<br />

P-TUE-178<br />

P-TUE-179<br />

P-TUE-180<br />

P-TUE-181<br />

P-TUE-182<br />

P-TUE-183<br />

P-TUE-184<br />

P-TUE-185<br />

P-TUE-186<br />

P-TUE-187<br />

P-TUE-188<br />

Software Supported Process Optimization For Magnetic Beads Purification Of<br />

Glycoproteins<br />

Ulrike Schweiger-Hufnagel (Bruker Daltonik GmbH, GERMANY), Peter Hufnagel,<br />

Stefan Weise, Arnd Asperger, Katrin Sparbier, Irina Kessler, Markus Kostrzewa,<br />

Detlev Suckau<br />

WIelding The Double Edged Sword Of Multiple Ms/Ms Searching Engines<br />

Brian Searle (Proteome Software Inc., UNITED STATES), Mark Turner<br />

Protein Identification With Linear Programming<br />

Oliver Serang (University of Washington, UNITED STATES)<br />

Extensive Peptide Identification Via Sequence Temperature Values And Feature<br />

Probabilities<br />

Sean L. Seymour (Applied Biosystems|Mds Analytical Technologies, UNITED STATES),<br />

Ignat V. Shilov, Alpesh A. Patel, Wilfred H. Tang, Alex Loboda, Christie L. Hunter,<br />

Lydia M. Nuwaysir, Daniel A. Schaeffer<br />

Protein Methylation Site Prediction Using Profile-Based Bayesian Kernel Feature<br />

Extraction<br />

Jianlin Shao (Department of Biology, The Chinese University of Hong Kong, CHINA),<br />

Saiming Ngai<br />

Iprophet: Improved Validation Of Peptide Identification In Shotgun Proteomics.<br />

David Shteynberg (Institute for Systems Biology, UNITED STATES), Eric Deutsch,<br />

Henry Lam, Ruedi Aebersold, Alexey Nesvizhskii<br />

Rapid Proteome Profiling And Genome Annotation Using Positional Signature Peptides<br />

Jennifer Siepen (University of Manchester, UNITED KINGDOM), Lucy Mcdonald,<br />

James Wright, Robert Beynon, Simon Hubbard<br />

N-Dimensional Grouping As A Tool For Mining Proteomic Expression Profiling Data<br />

Stephen Tate (Mds Analytical Technologies, CANADA), Devando Pinto, Ron Bonner,<br />

Lyle Burton, Gordana Ivosev<br />

Proteomics Pipelining And Profiling Of Mass Spectrometry Data (P²M)<br />

Felix Tschoerner (Experimental Ophthalmology, Department of Ophthalmology, University<br />

of Mainz, GERMANY), Phllip Kroll, Marcel Blindert, Nils Boehm, Norbert Pfeiffer, Franz Grus<br />

Predicting Protein-Protein Interaction Motifs Based On Proteomic Interaction Data<br />

Aalt-Jan van Dijk (Plant Research International, Wageningen Ur, THE NETHERLANDS),<br />

Cajo ter Braak, Richard Immink, Gerco Angenent, Roeland van Ham<br />

Comparative Functional Analysis Of The Caenorhabditis Elegans And Drosophila<br />

Melanogaster Proteomes<br />

Manuel Weiss (University of Zurich, SWITZERLAND)<br />

Spectral Profile Libraries For Cross Species Proteomics<br />

James Wright (Veterinary Pre-Clinical Sciences, The University of Liverpool / Faculty<br />

of Life Sciences, The University of Manchester, UNITED KINGDOM), Simon Hubbard,<br />

Robert Beynon<br />

ProConf: A New Method To Estimate The False Positive Ratio Employing<br />

Hypergeometric Distribution Model<br />

Songfeng Wu (Beijing Proteome Research Center, CHINA), Ning Li, Jie Ma, Yunping<br />

Zhu, Fuchu He<br />

P-TUE-189<br />

P-TUE-<strong>19</strong>0<br />

P-TUE-<strong>19</strong>1<br />

P-TUE-<strong>19</strong>2<br />

P-TUE-<strong>19</strong>3<br />

Connecting Nci Proteomics Repository To The Cancer Biomedical Informatics<br />

Grid (Cabig)<br />

Liming Yang (National Cancer Institute, UNITED STATES), Denny Chan, Carl Blake,<br />

Carl Schaefer<br />

High Confident Protein Id Of Etd And Ecd Spectra With A New Mass List<br />

Preprocessor<br />

Martin Zeller (Thermo Fisher Scientific, GERMANY), Bernard Delanghe, Torsten Ueckert<br />

An Innovative Algorithm For Sequence Motif Search<br />

Jianjun Zhang (Genentech Inc., UNITED STATES), Colin Watanabe<br />

Msaq: A New Software For Quantitative Proteomic Analysis With Stable<br />

Isotope-Coded Labeling<br />

Jiyang Zhang, Xin Liu, Hongwei Xie, Yunping Zhu (State Key Laboratory of<br />

Proteomics / Beijing Proteome Research Center / Beijing Institute of Radiation<br />

Medicine, CHINA), Xiaohong Qian, Fuchu He<br />

Prelocabc-- A Novel Predictor For Proteins’ Subcellular Localization By A<br />

Bayesian Classifier<br />

Yanqiong Zhang, Tao Li, Chunyuan Yang, Yunping Zhu (State Key Laboratory of<br />

Proteomics / Beijing Proteome Research Center / Beijing Institute of Radiation<br />

Medicine, CHINA), Fuchu He<br />

Glycoproteomics<br />

P-TUE-<strong>19</strong>4<br />

P-TUE-<strong>19</strong>5<br />

P-TUE-<strong>19</strong>6<br />

P-TUE-<strong>19</strong>7<br />

P-TUE-<strong>19</strong>8<br />

P-TUE-<strong>19</strong>9<br />

P-TUE-200<br />

P-TUE-201<br />

The Er N-Glycoproteome Research Of C57bl/6j Mouse<br />

Yun Cai (State Key Laboratory of Proteomics, Beijing Proteome Research Center.<br />

Beijing Institute of Radiation Medicine, CHINA)<br />

Proteomics Approach To Identify Serum Glycoproteins As Biomarkers Of Human<br />

Lung Adenocarcinoma<br />

Chu-Ling Wen (Graguate Institute of Biochemistry and Molecularbiology, Collage of<br />

Medicine, National Taiwan University, TAIWAN), Lu-Ping Chow<br />

Characterization Of Ptms And Their Effect On Enzyme Activity And Stability<br />

Maja Christiansen (Novozymes A/S University of Southern Denmark, DENMARK),<br />

Carsten Sönksen, Christian Jørgensen, Ole Jensen<br />

Glycation Plasma Proteome In Gestational Diabetes Predisposed To Preeclampsia<br />

Cc Wang (The Chinese University of Hong Kong, CHINA), Cy Chu, Tcw Poon, Wh Tam,<br />

Cy Li, Ms Rogers<br />

Glycoproteomics Of Paclitaxel Chemoresistance In Ovarian Cancer Cell Lines<br />

Michela di Michele (Catholic University, ITALY), Anna della Corte, Lucia Cicchillitti,<br />

Piero del Boccio, Andrea Urbani, Cristiano Ferlini<br />

Withdrawn<br />

Glycoproteomics: Analysis Of Carbohydrate Msms Fragment Ion Spectra By<br />

Database Searching<br />

Matthias Glueckmann, Donna Potts (Applied Biosystems, GERMANY), Christof Lenz,<br />

Lydia Nuwaysir, Ningombam Sanjib Meitei, Radha Nigam, Kamal Kishore<br />

Glycan Analysis By Capillary Electrophoresis Coupled To High Resolution Mass<br />

Spectrometry<br />

Carolin Huhn (Aalen University, GERMANY), L Renee Ruhaak, André M. Deelder,<br />

Manfred Wuhrer, Christian Neusüß<br />

112 113


P-TUE-202<br />

Glycomics Of Dmbt1sag: Potential Bacterial Binding Of Identified<br />

Polyfucosylated Lewis Type O-Linked Glycans<br />

Samah Issa (National University of Ireland Galway, IRELAND), Niclas Karlsson,<br />

Antoon Ligtenberg<br />

P-TUE-215<br />

A High Througput Sample Preparation Method For N-Glycan Profiling Of Plasma<br />

Glycoproteins<br />

L Renee Ruhaak (Leiden University Medical Center, THE NETHERLANDS), Manfred<br />

Wuhrer, Carolien A.M. Koeleman, Cornelis H. Hokke, Andre M. Deelder<br />

P-TUE-203<br />

De Novo Glycan Structure Search With Cid Ms/Ms Spectra Of Native<br />

N-Glycopeptides<br />

Hannu Peltoniemi (Medicel Ltd, FINLAND), Sakari Joenväärä, Risto Renkonen<br />

P-TUE-216<br />

Comparative Glycoproteomics Of Campylobacter Jejuni: An Insight Into Clinical<br />

Differences<br />

Nichollas Scott (University of Sydney, AUSTRALIA), Stuart Cordwell<br />

P-TUE-204<br />

P-TUE-205<br />

P-TUE-206<br />

P-TUE-207<br />

P-TUE-208<br />

P-TUE-209<br />

P-TUE-210<br />

N-Glycoproteomics - An Automated Workflow Approach<br />

Sakari Joenväärä (Medicel Ltd, FINLAND), Ilja Ritamo, Hannu Peltoniemi, Risto Renkonen<br />

Human Salivary Mucins: Mg2 (Muc7) Glycosylation Is Consistent, Whereas<br />

Mg1 (Muc5b) Glycosylation Varies Extensively Between Healthy Individuals<br />

Niclas Karlsson (Centre for Bioanalytical ScIences, Nui Galway, IRELAND), Kristina<br />

Thomsson, Nicolle Packer<br />

Glycoproteins Expressed Differentially In Mouse Exposed By Mercury Chloride<br />

Bong-Hwa Kim (Department of Molecular Medicine, KOREA), Hee-Young Son, Pyong-<br />

Gon Moon, Hong-Bae Jeon, Mi-Na Song, Sang-Hyun Kim, Moon-Chang Baek<br />

Improved Glycopeptide Profiling Of Pharmaceutical Compounds By Novel<br />

Enrichment Strategies<br />

Peter Leland (Emd Chemicals, Inc., UNITED STATES), Jessica Wohlgemuth, Thomas<br />

Eichhorn, Christian Hunzinger, Robertus Hendriks, Sven Andrecht<br />

Glycoblotting For Quantitative N- And O-Glycomics In Disease Diagnosis<br />

Yoshiaki Miura (Hokkaido University, JAPAN), Yasuro Shinohara, Jun-Ichi Furukawa,<br />

Shin-Ichiro Nishimura<br />

Mass Spectrometric Study Of Fgf-2 Glycation<br />

Helen Montgomery (Koichi Tanaka Mass Spec. Research Lab., Shimadzu, UNITED<br />

KINGDOM), Omar Belgacem, A Qadeer, Nessar Ahmed<br />

Boronic Acid Lectin Affinity Chromatography (Blac) In Glycoproteomics<br />

Alex Monzo (Horvath Laboratory of Bioseparation Sciences, AUSTRIA), Marcell<br />

Olajos, Lorenzo De Benedictis, Guenther Bonn, Andras Guttman<br />

P-TUE-217<br />

P-TUE-218<br />

P-TUE-2<strong>19</strong><br />

P-TUE-220<br />

P-TUE-221<br />

P-TUE-222<br />

Disease Related Changes In The Glycosylation Pattern Of Serum Igg Analyzed By<br />

Maldi-Tof Ms<br />

Katrin Sparbier, Hassan Dihazi, Sabine Blaschke, Gerd-Anton Mueller, Thomas Flad,<br />

Markus Kostrzewa (Bruker Daltonik GmbH, GERMANY)<br />

Effect Of Glycosylation On The Extracellular Domain Of The Ag43 Bacterial<br />

Autotransporter<br />

Allan Stensballe (University of Aalborg, DENMARK), Daniel Otzen, Stine K. Knudsen<br />

Quantitative Proteomic Approach To Profile Phosphorylation And Glycosylation<br />

Changes In Mammalian Cells In Response To Hypoxia Treatment<br />

Safia Thaminy (Institute for Systems Biology, UNITED STATES), Yong Zhou, Mi-Youn<br />

Brusniak, Ning Zhang, Jingchun Chen, Simon Letarte, Carey Sheu, Julian Watts,<br />

Ruedi Aebersold<br />

High-Sensitivity Nano- And Capillary-Lc/Ms For Mucin O-Glycan Profiling<br />

Kristina Thomsson (Institute of Biomedicine, Göteborg University, SWEDEN), Malin<br />

Bäckström, Hasse Karlsson, Gunnar C. Hansson<br />

A Proteomic Approach To Detect Galectin-3 Ligands From Human Neutrophils<br />

Gisele Tomazella (Centro de Química de Proteínas - Unfesp, BRAZIL), Gustavo de<br />

Souza, Idalete da Silva, Harald Wiker, Roger Chammas, Lewis Greene<br />

Sweet Success: Characterizing O-Glcnac Sites With Electron Transfer<br />

Dissociation Ms<br />

Namrata Udeshi (Department of Chemistry, University of Virginia, UNITED STATES),<br />

Youn-Cheon Kim, Michael Housley, Gerald Hart, Neil Olszewski, Jeffrey Shabanowitz,<br />

Donald Hunt<br />

P-TUE-211<br />

P-TUE-212<br />

P-TUE-213<br />

Spot The Difference: What Is A Normal Glycomic Profile?<br />

Nicolle Packer (Macquarie University, AUSTRALIA), Pia Hønnerup-Jensen, Daniel<br />

Kolarich<br />

Mass Spectrometric Characterization Of Glycosylation In Antiophidic Proteins<br />

Dm43 and Dm64<br />

Ileana R. León, Jonas Perales (Oswaldo Cruz Foundation-Fiocruz / Rio De Janeiro<br />

Proteomic Network, BRAZIL), Ana G.C. Neves-Ferreira, Surza L.G. Rocha, Monique<br />

R.O. Trugilho, Daniela G. Beghini, Richard H. Valente<br />

Study Of Glycations Of Barley Lipid Transfer Proteins<br />

Inga Petry-Podgorska (Institute of Analytical Chemistry of The Ascr, CZECH<br />

REPUBLIC), Karel Mazanec, Janette Bobalova<br />

P-TUE-223<br />

P-TUE-224<br />

P-TUE-225<br />

N-Glycome Of Mesenchymal Stem Cells Can Be Used To Evaluate Cellular<br />

Differentiation<br />

Leena Valmu (Finnish Red Cross Blood Service, FINLAND), Suvi Natunen, Tero<br />

Satomaa, Annamari Heiskanen, Jari Natunen, Sari Tiitinen, Ulla Impola, Petri<br />

Lehenkari, Juhani Saarinen<br />

Withdrawn<br />

Automatic Interpretation Strategy For Ms-Based Analysis Of Standard<br />

Glycoproteins<br />

Yang Zhang (Institutes of Biomedical Sciences, Fudan University, CHINA)<br />

P-TUE-214<br />

Glycoproteomics: Applications For Stem Cell And Cancer Biomarkers<br />

Michael Pierce (Center for Biomedical Glycomics, Complex Carbohydrate Research<br />

Center, University of Georgia, UNITED STATES), Steven Dalton, Kelley Moremen,<br />

Michael Tiemeyer, Lance Wells, Ron Orlando, Karen Abbott, Gerardo Alvarez-Manilla,<br />

William York<br />

114 115


Mass Spectrometric Innovations<br />

P-TUE-226<br />

P-TUE-227<br />

P-TUE-228<br />

P-TUE-229<br />

P-TUE-230<br />

P-TUE-231<br />

Enhancing Linear Ion Trap Mass Spectrometry Etd Performance Using<br />

Supplemental Activation<br />

Zhiqi Hao, Jae Schwartz, John Syka, Andreas Huhmer (Thermo Fisher Scientific,<br />

UNITED STATES)<br />

Characterization Of Small Molecule-Protein Interaction Site By Combined<br />

Scanning Mode-Ion Filtering In A Hybrid Triple Quadrupole<br />

Enrique Calvo (Cnic, SPAIN), Emilio Camafeita, Juan Antonio Lopez<br />

N-Terminal Plasma Profiling In Biomarker Discovery<br />

Gemma Davidson (University of Liverpool, UNITED KINGDOM), Lucy Mcdonald,<br />

Duncan Robertson, Robert Beynon<br />

Metal-Imaging Mass Spectrometry (Mims): An Imaging Mass Spectrometry<br />

Technology To Determine The Distribution Of Metal Ions In Tissue Samples.<br />

Philip Doble (University of Technology Sydney, AUSTRALIA)<br />

Optimization Of Intact Pprotein Funnel-Skimmer Dissociation For Ftms<br />

Jennifer S. Cobb, Michael L. Easterling (Bruker Daltonics Inc., UNITED STATES),<br />

Jeffrey N. Agar<br />

Mass Spectrometric Analysis Of Plasma Proteins Using An Experimental Design:<br />

Challenges & Perspectives<br />

Srinubabu Gedela (Andhra University College of Engineering, India), Appa Rao Allam<br />

P-TUE-239<br />

P-TUE-240<br />

P-TUE-241<br />

P-TUE-242<br />

P-TUE-243<br />

P-TUE-244<br />

Full Automation Of Sample Preparation On Maldi Targets Using Stagetips<br />

Christopher Loessner (German Cancer Research Center, GERMANY), Heinrich<br />

Gausepohl, Martina Schnolzer<br />

A Simple And Efficient Concept For Etd and Ptr In A Spherical Ion Trap<br />

Ralf Hartmer, Markus Lubeck (Bruker Daltonik GmbH, GERMANY), Andreas<br />

Brekenfeld, Carsten Baessmann, Arnd Ingendoh<br />

Hplc–Ms Analysis Of Large Peptides And Intact Proteins Using Etd and Ptr<br />

Ion/Ion Reactions<br />

Andreas Leinenbach, Markus Lubeck, Ralf Hartmer, Carsten Baessmann, Christian<br />

Huber, Christian Albers (Bruker Daltonik, GERMANY)<br />

Combination Of Lc-Ms and Lc-Ms/Ms Datasets In Bottom-Up Proteomics<br />

Magnus Palmblad (Leiden University Medical Center, THE NETHERLANDS), Yuri van<br />

der Burgt, Hans Dalebout, André Deelder<br />

Lc/Ms Intact Mass Analysis Of Immunoglobulin Gamma Antibodies By Ltq-<br />

Orbitrap<br />

Pavel V. Bondarenko, Tonya Pekar Second (Thermo Fisher, UNITED KINGDOM), Vlad<br />

Zabrouskov, Alexander A. Makarov, Zhongqi Zhang<br />

An Ipg Mudpit Workflow For Ms Analysis Of Protein Complexes Purified By Blue<br />

Native Gels<br />

Mahbod Hajivandi (Invitrogen, UNITED STATES), Thomas Beardslee, Xiquan Liang,<br />

Paul Predki, R Marshall Pope<br />

P-TUE-232<br />

P-TUE-233<br />

P-TUE-234<br />

P-TUE-235<br />

P-TUE-236<br />

P-TUE-237<br />

Analyzing Plasma Proteome With Electron Transfer Dissociation And Proton<br />

Transfer Reaction<br />

Sarah Hart (University of Manchester, UNITED KINGDOM), Richard Blankley,<br />

Carsten Baessmann, Markus Lubeck, Laura Main, Simon Gaskell<br />

Evaluation Of Etd In A Hybrid Qh-Ftms Proteins<br />

Michael Easterling, Ralf Hartmer (Bruker Daltonik GmbH, GERMANY), Jiong Yang,<br />

Melvin A. Park<br />

Improved Coverage In Global Bottom Up Proteomics Survey Experiments By<br />

Decreasing Cycle Time On A Linear Ion Trap Mass Spectrometer<br />

Julian Phillips (Thermo Fisher Scientific, UNITED STATES), Julie Horner, Amy<br />

Zumwalt, Andreas Huhmer<br />

Optimization Of Parameters For Protein And Peptide Analysis Using High Field<br />

Asymmetric Waveform Ion Mobility Spectrometry (Faims)<br />

Julie Hornerr (Thermo Fisher Scientific, UNITED STATES), Sucharita Dutta, Julian<br />

Phillips, Mark Sanders<br />

Using Ims To Separate Precursors From Species Of Different Charges In Tandem<br />

Ms Analyses<br />

Chris Hughes (Waters Ms Technologies Centre, Manchester, UNITED KINGDOM),<br />

Therese Mckenna, Jim Langridge<br />

Specific Maldi Imaging Using Oligonucleotides, Antibodies And Lectins<br />

Amelie Laure Jacquet (Maldi Imaging Team Ustl, FRANCE), Mohamed El Ayed,<br />

Marchald Deschamp, I Rudolff, GG Proess, Maxence M. Wisztorski, Isabelle Fournier,<br />

Michel Salzet<br />

P-TUE-245<br />

P-TUE-246<br />

P-TUE-247<br />

P-TUE-248<br />

P-TUE-249<br />

P-TUE-250<br />

Imaldi+: A Targeted Proteomics Approach To Clinical Diagnostics<br />

Brinda Shah (Uvic Genome Bc Proteomics Centre / University of Victoria, CANADA),<br />

Jennifer Reid, Christoph Borchers<br />

Unprecedented Mass Accuracy Using Orbitrap Mass Spectrometry<br />

Richard Scheltema (University of Groningen, THE NETHERLANDS), David Wildridge,<br />

Michael Barrett, Ritsert Jansen, Rainer Breitling<br />

Continuously Monitoring The States Of Tryptic Digestion Processes Of Proteins<br />

By Ambient Liquid Mass Spectrometry (Alms)<br />

Jentaie Shiea, Cheng-Hui Yuan (Department of Chemistry, National Sun Yat-Sen<br />

University, TAIWAN), Jingyueh Jeng, Chih-Yuan Cheng, Li-Hua Lo<br />

Nano-Esi And Ion Trap-Etd/Ptr-Ms/Ms For The Analysis Of Post-Translational<br />

Modifications<br />

Frank Sobott (Oxford University, UNITED KINGDOM)<br />

Targeted Assignment Of Protein N- And C-Termini In Protein Samples By A<br />

Comprehensive Top-Down Lc-Maldi-Isd Sequencing Strategy<br />

Detlev Suckau (Bruker Daltonics, GERMANY), Anja Resemann<br />

Fast And Accurate Determination Of Monoisotopic Masses Of Polypeptides From<br />

Ftms<br />

Kunsoo Park, Joo Young Yoon, Sunho Lee, Eunok Paek (University of Seoul, KOREA),<br />

Heejin Park, Sang-Won Lee<br />

P-TUE-238<br />

A New Peptide Profiling Technology For Early Diagnosis And Personalized Medicine<br />

Lyang-Ja Lee (Protosera Inc., JAPAN), Kenji Tanaka, Nobuya Sanuki, Ushio Takeda,<br />

Kazuhiro Ishida, Teruto Hashiguchi, Ikurou Maruyama<br />

116 117


Phosphoproteomics<br />

P-TUE-251<br />

P-TUE-252<br />

P-TUE-253<br />

Evaluation Of Chemical Beta-Elimination For Analysis Of Phosphorylated Peptides<br />

Nicolai Bache (University of Southern Denmark, DENMARK), Martin Røssel Larsen<br />

Cerebrospinal Fluid Phosphoproteome Investigated Using Tio2 Chromatography<br />

And Mass Spectrometry<br />

Justyna Bahl (Statens Serum Institut, Dpt. of Autoimmunology, DENMARK), Søren<br />

Jensen, Martin Larsen, Niels Heegaard<br />

A Comprehensive Phosphoproteome Workflow<br />

Roger G. Biringer (Thermo Fisher Scientific, UNITED STATES), Zhiqi Hao, Michael G.<br />

Harrington, Andreas F.R. Hühmer<br />

P-TUE-263<br />

P-TUE-264<br />

P-TUE-265<br />

Serine 395, Controls Transcriptional Activity In The Aryl Hydrocarbon Receptor<br />

Alan Friedman (University of Rochester, UNITED STATES), Brent Kobielush, Gary<br />

Minsavage, Daria Vorojeikina, Mike Easterling, Thomas Gasiewicz<br />

Phosphoproteome Profiling Of Human Lung Cancer<br />

Angelo Gámez-Pozo (Hospital Universitario La Paz, SPAIN), Iker Sánchez-Navarro,<br />

Enrique Calvo, Manuel Nistal, JavIer de Castro, Enrique Espinosa, Juan Antonio<br />

López, Manuel González-Barán, Juan Ángel Fresno Vara, E Camafeita<br />

Protein Phosphorylation Characterization By Maldi-Tof Mass Spectrometry<br />

With The Improved Matrix Layer Sample Preparation<br />

Ignazio Garaguso (Fraunhofer Institute of Toxicology and Experimental Medicine,<br />

GERMANY), Juergen Borlak<br />

P-TUE-254<br />

P-TUE-255<br />

P-TUE-256<br />

P-TUE-257<br />

P-TUE-258<br />

P-TUE-259<br />

Automated Serum Phosphopeptide Profiling Of Glaucoma Patients<br />

Nils Boehm (Experimental Ophthalmology, Department of Ophthalmology, University<br />

of Mainz, GERMANY), Joachim Richter, Susanne Rosfa, Stephanie Joachim, Norbert<br />

Pfeiffer, Franz Grus<br />

Phosphorylation-Specific Interaction And Regulation Of Vasp In Platelets<br />

Julia Burkhart (Protein Mass Spectrometry and Functional Proteomics Group<br />

Rudolf-Virchow-Center, GERMANY), Thomas Premsler, Peter Benz, Michaela Kuhn,<br />

Thomas Renné, Albert Sickmann<br />

First Round And Second Round Search Engines For Analyzing Post-Translational<br />

Modifications Such As Phosphorylation<br />

M Blueggel, LM Freimark, RJ Shaw, DC Chamrad, C Huels (Protagen Ag, GERMANY),<br />

JM Asara<br />

Phosphoproteomic Analysis Of Oxidative Stress In Epithelial Cells: Major Role Of<br />

Src Kinase-Dependent Phosphorylation In Regulating Adhesion<br />

Hong-Lin Chan, Hsiu-Chuan Chou, Jana Gruenewald, Michael Waterfield, Anne Ridley,<br />

John Timms (Ega Institute for Women’s Health, University College London, UNITED<br />

KINGDOM)<br />

Quantitative Phosphoproteome Analysis Applied To The Human Neural Stem Cell<br />

Kun Cho (Mass Spectrometry Research Team, Korea Basic Science Institute,<br />

KOREA), Eunmin Kim, Gun Wook Park, Jeong Hwa Lee, Yeong Hee Ahn, Kyung-Hoon<br />

Kwon, Jin Young Kim, Kyung Hee Byun, Bong Hee Lee, Jong Shin Yoo<br />

Anchoring Phosphorylation To Surfaces For Localisation And Enrichment Studies<br />

Garry Corthals (Turku Centre for Biotechnology / University of Turku/ Åbo Akademi<br />

University, FINLAND), Petri Kouvonen, Susumu Imanishi, John Eriksson, Eeva Rainio,<br />

Päivi Koskinen, Anne Rokka, Mika Linden, Jan-Henrik Smått<br />

P-TUE-266<br />

P-TUE-267<br />

P-TUE-268<br />

P-TUE-269<br />

P-TUE-270<br />

P-TUE-271<br />

P-TUE-272<br />

Strategies For Finding The Most Important Phosphorylation Sites In A Protein<br />

Mark Graham (Children’s Medical Research Institute, AUSTRALIA), Ling Chan, Phillip<br />

Robinson<br />

Quantification Of Tyrosine Phosphorylation By Affinity Enrichment And Isotopic Labelling<br />

Peter Hoffmann (University of Adelaide, AUSTRALIA), Mark R. Condina, Shaun R. Mccoll<br />

Cid And Etd Analysis Of Kinase Sites Of Phosporylation With High Mass<br />

Accuracy Measurement<br />

Martin Hornshaw (Thermo Fisher Scientific, UNITED KINGDOM), Kai Scheffler,<br />

Martin Zeller, Nick Morrice<br />

Phosphoproteomic Signature In Lung Cancer Metastasis Revealed By A Label-<br />

Free Strategy<br />

Chuan-Chih Hsu (Department of Chemistry, National TAIWAN University / Institute of<br />

Chemistry, Academia Sinica, TAIWAN), Yi-Ting Wang, Chia-Feng Tsai, Pei-Yi Lin, Tzu-<br />

Chan Hong, Chih-Chiang Tsou, Wen-Lian Hsu, Ting-Yi Sung, Tze-Min Hong, Yu-Ju Chen<br />

Phosphoproteome Analysis Of Estrogen-Induced Breast Cancer Cell Signaling<br />

Koshi Imami (Institute for Advanced Biosciences, Keio University, JAPAN), Naoyuki<br />

Sugiyama, Yutaka Kyono, Masaru Tomita, Yasushi Ishihama<br />

Comparative Cid and Etd Of Enriched Hydrophobic Peptides Of H. Salinarum<br />

Membrane Proteins<br />

Arnd Ingendoh (Bruker Daltonik GmbH, GERMANY), Christian Klein, Frank Siedler,<br />

Dieter Oesterhelt, Beatrix Scheffer, Friedhelm Peiffer<br />

Acidic Amino Acid Modifications In Proteins/Peptides From Frog Skin Secretion<br />

Lene A. Jakobsen (University of Southern Denmark, DENMARK), Tianbao Chen, Chris<br />

Shaw, Martin R. Larsen<br />

P-TUE-260<br />

Proteomics Screen To Identify 14-3-3 Binding Partners Regulated By Insulin<br />

Fanny Dubois (Mrc Protein Phosphorylation Unit, UNITED KINGDOM), Franck<br />

Vandermoere, Rachel Toth, Nicholas Morrice, Carol Mackintosh<br />

P-TUE-273<br />

A New Sample Prep Tool For Enrichment Of Phospho-Peptides Using Phos Spintrap Fe<br />

Lena Jonsson (Ge Healthcare, SWEDEN), Johan Öhman, Ann-Marie Nissfolk, Marika<br />

Sjödahl, Inger Salomonsson, Ulf Hellberg, Helena Hedlund<br />

P-TUE-261<br />

P-TUE-262<br />

Comparative Analysis Of The Human Kinome Phosphorylation At Distinct Mitotic<br />

Stages<br />

Kalyan Dulla (Dept of Cell Biology, Max Planck Institute of Biochemie, GERMANY),<br />

Henrik Daub, Renate Hornberger, Albert Ries, Erich A. Nigg, Roman Körner<br />

Comprehensive Strategy For Characterization Of Phosphorylation Events In The<br />

Il-1β Pathway<br />

Kasper Engholm-Keller (University of Southern Denmark, DENMARK), Søren Skov<br />

Jensen, Flemming Pociot, Martin Røssel Larsen<br />

P-TUE-274<br />

P-TUE-275<br />

Array Based Protein Expression Analysis Cell Signalling In Murine Hepatocellular<br />

Carcinomas<br />

Thomas Knorpp (Nmi - Natural and Medical Sciences Institute at The University of<br />

Tübingen, GERMANY), Berthold Gierke, Philip Marx-Stölting, Michael Pawlak, Michael<br />

Schwarz, Markus F. Templin<br />

Performing Phosphopetide Analysis On A Titanium Dioxide Based Enrichment And<br />

Separation Chip<br />

Karsten Kraiczek (Utrecht University Biomolecular Ms and Proteomics Group, GERMANY),<br />

Shabaz Mohammed, Martijn Pinkse, Reinout Raijmakers, Tom van de Goor, Albert<br />

Heck, Simone Lemeer<br />

118 1<strong>19</strong>


P-TUE-276<br />

Dissection Of The Insulin And Igf-1 Signaling Pathways By Quantitative Proteomics<br />

Irina Kratchmarova (Dep. of Biochemistry and Molecular Biology, University of<br />

Southern Denmark, DENMARK)<br />

P-TUE-288<br />

Enrichment And Separation Of Phosphopeptides Using Free Flow Electrophoresis<br />

Mikkel Nissum, Sabine Kronbauer, Robert Wildgruber (Bd Diagnostics, GERMANY),<br />

Craig Gelfand, Christoph Eckerskorn, David Craft<br />

P-TUE-277<br />

Arthritis-Inducible Protein, Annexin Vii: High Phosphorylation In Rheumatoid Arthritis<br />

Manae Kurokawa (Clinical Proteomics & Molecular Medicine, St. Marianna University<br />

School of Medi, JAPAN), Kosuke Matsuo, Hiroshi Nakamura, Kayo Masuko, Kazuki<br />

Okamoto, Tomohiro Kato<br />

P-TUE-289<br />

Global Phosphopeptide Profiling In Lncap-Cells<br />

Heike Piechura (Medizinisches Proteom-Center, Ruhr-Universitaet Bochum,<br />

GERMANY), Sebastian WIese, Christian Bunse, Eva M. Neuhaus, Hanns H. Hatt,<br />

Helmut E. Meyer, Bettina Warscheid<br />

P-TUE-278<br />

P-TUE-279<br />

P-TUE-280<br />

P-TUE-281<br />

P-TUE-282<br />

P-TUE-283<br />

P-TUE-284<br />

Quantitative Phosphoproteomics Of Depolarized Nerve Terminals.<br />

Martin R. Larsen (University of Southern Denmark, DENMARK), Mark E. Graham,<br />

Phillip J. Robinson<br />

Discovery Of Phosphoprotein Hepatocellular Carcinoma Biomarkers Using A Fully<br />

Automated Tio2-Based 3dlc (Scx/Tio2/C18)-Ms/Ms Method<br />

Hyoung-Joo Lee (Yonsei Proteome Research Center, Biomedical Proteome Research<br />

Center, Department of Biochemistry, KOREA), Keun Na, Min-Seok Kwon, Min-Jeong<br />

Kang, Hoguen Kim, Young-Ki Paik<br />

Novel Tyrosine Kinase Substrates In Oncogenic Egf Signaling And Breast Cancer<br />

Development<br />

Yoon Pin Lim (National University of Singapore, Singapore), Yunhao Chen, Lee Yee<br />

Choong, Qingsong Lin, Robin Philp<br />

Targeted Srm Assays Of Cell Lysate Phosphopeptides Enriched By Automated,<br />

Magnetic Bead-Based System<br />

Mary F. Lopez, Bryan Krastins (Thermofisher Scientific, UNITED STATES), David<br />

Sarracino, John Rogers, Paul Haney, Michael Athanas, Amol Prakash<br />

Insulin Dosages Mediate Irs-1 Phosphorylation Patterns That Are Associated<br />

With Positive And Negative Signaling Effects<br />

Xiao-Ming Lu (Massachusetts General Hospital, Harvard Medical School / The<br />

Shriners Hospital for Children, UNITED STATES), Amy Lu, Edward Carter, Joseph<br />

Avruch, Ronald Tompkins, Alan Fischman<br />

Enhanced Phosphopeptide Detection And Sequencing Using Uplc With A Tandem<br />

Quadrupole<br />

Therese Mckenna, Daniel J. Kenny, James I. Langridge (Waters Corporation, UNITED<br />

KINGDOM)<br />

Characterization Of Foxm1 Phosphorylation Sites Using Online Tio2<br />

Phosphopeptide Enrichment<br />

Jamila Laoukili, Monica Alvarez, Lars Meijer (Department of Physiological Chemistry and<br />

Centre for Biomedical Genetics, University Medical Center Utrecht, THE NETHERLANDS),<br />

Marie Stahl, Shabaz Mohammed, Livio Kleij, Albert Heck, René Medema<br />

P-TUE-290<br />

P-TUE-291<br />

P-TUE-292<br />

P-TUE-293<br />

P-TUE-294<br />

P-TUE-295<br />

P-TUE-296<br />

Characterization Of Imac And Tio2 In The Study Of Dynamic Regulation Of<br />

Phosphorylation<br />

Xiquan Liang (Invitrogen, UNITED STATES), Gier Fonnum, Mahbod Hajivandi, Torkel<br />

Stene, Nini H. Kjus, Erlend Ragnhildstveit, Joseph W. Amshey, Paul Predki, R<br />

Marshall Pope<br />

Phosphorylation-Specific Interaction And Regulation Of Vasodilator-Stimulated<br />

Phosphoprotein<br />

Thomas Premsler (Rudolf-Virchow-Center for Experimental Biomedicine, Protein<br />

Mass Spectrometry, University of Wuerzburg, GERMANY), Julia Maria Burkhart,<br />

Albert Sickmann, Peter Benz, Thomas Renné, Michaela Kuhn<br />

Analysis Of Stoichiometry Of Protein Phosphorylation In Adipocyte Lipid<br />

Droplets By Isotopic Tagging<br />

Alexey Pshezhetsky (Deps of Pediatrics And Biochemistry, University of Montreal<br />

/ Department of Medical Genetics, Sainte-Justine Hospital, CANADA), Eugenii<br />

Kanshin, Shu Pei Wang, Mila Ashmarina, Grant Mitchell, Ilya Nifant’ev<br />

Imatinib Resistance In Cml Is Caused By Bcr-Abl-Independent Activation Of<br />

Raf<br />

Julia Rosenhahn (Institute of Human Genetics and Anthopologie, Friedrich Schiller<br />

University Jena, GERMANY), Ignacio Rubio, Christina Hipler, Ivan F. Loncarevic,<br />

Ferdinand von Eggeling<br />

Multiple Protease Digestion Using Immobilized Enzymes: An Effective Sample<br />

Preparation Method For The Protein Structural Analysis By Mass Spectrometry.<br />

Yukie Sasakura (Hitachi High-Technologies, JAPAN), Ayumi Suzuki, Katsuhiro Kanda,<br />

Izumi Waki<br />

Plant Phosphoproteome By Hydroxy Acid-Modified Metal Oxide Chromatography<br />

(Hammoc)<br />

Naoyuki Sugiyama (Institute for Advanced Biosciences, Keio University / Human<br />

Metabolome Technologies, Inc., JAPAN), Hirofumi Nakagami, Sumiko Ohnuma, Keiichi<br />

Mochida, Arsalan Daudi, Masaru Tomita, Ken Shirasu, Yasushi Ishihama<br />

Withdrawn<br />

P-TUE-285<br />

Online Automated Phosphoproteomics Using Tio2<br />

Martijn Pinkse, Shabaz Mohammed, Martina O’Flaherty (Biomolecular Mass<br />

Spectrometry and Proteomics Group, Utrecht University, THE NETHERLANDS),<br />

Simone Lemeer, Albert Heck<br />

P-TUE-297<br />

Targeting Biologically Important But Poorly Ionized Phosphopeptides Using Lc/<br />

Mrm/Ms/Ms<br />

Lorne Taylor (Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, CANADA),<br />

Andreas Traweger, Brett Larsen, David Cox, Stephen Tate, Tony Pawson<br />

P-TUE-286<br />

P-TUE-287<br />

Phosphoproteomic Analysis Of 3 Distinct Tumor Cell Lines Arrested At M-Phase<br />

Kohji Nagano (Chugai Pharmaceutical Co., Ltd., JAPAN), Takashi Shinkawa, Osamu<br />

Kondoh, Sayuri Morimoto, Noriyuki Inomata, Nobuya Ishii, Yuko Aoki, Masayuki<br />

Haramura<br />

Protein Phosphorylation Analysis And Quantification Of Mice Kidney Proteins By<br />

2d-DpAge And Icp-Ms<br />

Boris Neumann (Proteome Factory Ag, GERMANY), Karola Lehmann, Jens Altvater,<br />

Robert Ahrends, Franz Theuring, Christian Scheler<br />

P-TUE-298<br />

P-TUE-299<br />

Titanium Dioxide Coated MAldi Plate For On Target Analysis Of Phosphopeptides<br />

Federico Torta (San Raffaele Scientific Institute, ITALY), Angela Bachi, Matteo Fusi,<br />

Carlo S. Casari, Carlo E. Bottani<br />

Serine 395, Imporant For Transcriptional Activity In Mouse-Ahr, Is<br />

Phosphorylated By Pka<br />

Alan Friedman, Michael Easterling, Patrick van Houts (Bruker Daltonics Inc., UNITED<br />

STATES), Brent R. Kobielush, Daria Vorojeikina, Thomas A. Gasiewicz<br />

120 121


P-TUE-300<br />

P-TUE-301<br />

Evaluation Of The Low-Specificity Protease Elastase For Phosphoproteome<br />

Analysis<br />

Bin Wang (Max Planck Institute for Biochemistry, GERMANY), Rainer Malik, Albert<br />

Ries, Erich A. Nigg, Roman Körner<br />

Analysis Of Phosphopeptides By Alkaline Phosphatase Reactor And Micro-Hplc-<br />

Esi-Ms/Ms<br />

Hui Wang (Dalian Institute of Chemical Physics, Chinese Academy of Sciences,<br />

CHINA), Jicheng Duan, Zhen Liang, Lihua Zhang, Yukui Zhang<br />

P-TUE-313<br />

P-TUE-314<br />

Rainer Breitling, Maarteen Koornneef, Ritsert Jansen<br />

Peptid Markers To Identify Wheat Allergens<br />

Tamas Janaky (Department of Medical Chemistry, University of Szeged, Hungary),<br />

Eva Gelencser, Attila Csorba, Krisztina Takacs, Jeno Szamos<br />

The Effects Of Peripheral And Central Administration Of Hypericum Perforatum<br />

L. On Chronic And Acute Pain<br />

Farzaneh Biranvand (Medical Sciences, Iran), Mojtaba Khaksarian<br />

P-TUE-302<br />

P-TUE-303<br />

Specific And Efficient Enrichment Of Phosphopeptides For Phospho-Proteome<br />

Analysis By Mass Spectrometry<br />

Paige Weis (Emd Chemicals, UNITED STATES)<br />

Optimization Of Immobilized Metal Ion Affinity Chromatography For Phosphopeptide<br />

Enrichment Prior To Mass Spectrometry<br />

Juanying Ye (Protein Research Group, Department of Biochemistry and Molecular<br />

Biology, University of Southern Denmark, DENMARK), Xumin Zhang, Peter Roepstorff,<br />

Ole Nørregaard Jensen<br />

P-TUE-315<br />

P-TUE-316<br />

Studty Of Photochemical And Antinociceptive Properties Of Medicinal Plant<br />

Allium Jesdianum And Probable Role Of The Opioidergic System<br />

Mojtaba Khaksarian (University of Medical Science, Iran), Bahram Delfan, Behroz<br />

Ahmadi<br />

Compared Proteomic Of The Flag Leaves Senescence Between Rice 93-11 And<br />

Nipponbare<br />

Qingtao Lu (Institute of Botany, CHINA / Institute of Plant Science, SWITZERLAND),<br />

Wei Li, Congming Lu<br />

P-TUE-304<br />

P-TUE-305<br />

P-TUE-306<br />

Withdrawn<br />

Tyrosine-Phosphorylated Proteins Are Predominantly Localized In The Glomerulus<br />

Of Normal Rat Kidney<br />

Ying Zhang (Department of Structural Pathology, Institute of Neprhology, Niigata<br />

Graduate School of Medical and Dental Sciences, JAPAN), Yutaka Yoshida, Bo Xu,<br />

Masaaki Nameta, Eishin Yaoita, Hidehiko Fujinaka, Tadashi Yamamoto<br />

Comparative Analysis Of Phosphoproteome Between Human Cerebellum And<br />

Prefrontal Cortex<br />

Ning Fu (Shanghai Institutes for Biological Sciences, CHINA), Jie Dai, Yi-Xue Li, Jia-<br />

Rui Wu, Philipp Khaitovich, Rong Zeng<br />

Plant Proteomics<br />

P-TUE-307<br />

P-TUE-308<br />

P-TUE-309<br />

P-TUE-310<br />

P-TUE-311<br />

Lead Induced Changes On Proteome Of Catharanthus Roseus (L.) G.Don<br />

Palanisamy Arun Mozhi Varman (Bharathidasan University, India)<br />

Fungal Proteomics<br />

Vijai Bhadauria (State Key Laboratory for Agrobiotechnology, China Agricultural<br />

University, CHINA), You-Liang Peng<br />

Rapid Bioinformatic Comparative Analysis Of Cold Shock TreaTed Rice Proteome<br />

John Chakel (Proxeon A/S, DENMARK), Alexandre Podtelejnikov, K Neilson, J Chick,<br />

Paul Haynes<br />

Dehydration Stress Responsive Comparative Proteome Of Lathyrus Sativus, A<br />

Hardy Legume<br />

Arnab Chattopadhyay, Aarti Pandey, Deepti Bhushan, Lalit Agrawal, Asis Datta,<br />

Subhra Chakraborty, Niranjan Chakraborty (National Institute for Plant Genome<br />

Research, India)<br />

Mass Spectrometry Studies Of S-Nitrosylated Peptides In Plant Proteomics<br />

Lisa Elviri (University of Parma, ITALY), Francesca Speroni, Emanuela Vurro, Maria<br />

Careri, Alessandro Mangia, Roberto de Michele, Michela Zottini, Fiorella lo Schiavo<br />

P-TUE-317<br />

P-TUE-318<br />

P-TUE-3<strong>19</strong><br />

P-TUE-320<br />

P-TUE-321<br />

P-TUE-322<br />

The Changes In The Phospholipid Composition Of Nuclear Subfractions In Treated<br />

By Non-Thermal Electromagnetic Radiation Wheat Seedlings<br />

Liya Alexandrovna Minasbekyan (Yerevan State University, Armenia)<br />

2de and 2d-Lc Analysis Of Wheat Line Taichung29*6/Yr5 Inoculated With<br />

Stripe Rust Race Cy32<br />

Yinghong Pan (Institute of Crop Science, Chinese Academy of Agricultural Sciences<br />

/ Nfcri, CHINA), Shichang Xiu, Cheng Ma, Jing Liu, Zhaohui Zhang, Ji Luo<br />

The Proteome Of Arabidopsis Thaliana Analyzed By Electron Transfer<br />

Dissociation Utilizing High Mass Accuracy Measurements<br />

Kai Scheffler (Thermo Fisher Scientific, Dreieich, GERMANY), Martin Hornshaw,<br />

Martin Zeller, Bernd Mueller<br />

Ion Mobility Coupled To NanOspray Lc Adds Another Dimension Of Separation<br />

For Complex Proteomics Samples<br />

Michaela Scigelova (Thermo Fisher Scientific, Dreieich, GERMANY), Gary Woffendin,<br />

Martin Hornshaw, Kai Scheffler, Bernd Mueller<br />

Digging Into The Plant Proteome<br />

Sergey Sikora (Genway Biotech, Inc., UNITED STATES), Xiangming Fang, Li Deng,<br />

Wei-Wei Zhang<br />

Profiling The Proteome Of Chlamydomonas Reinhardtii (Green Algae) Exposed To<br />

Multiple Stressors<br />

Marc Suter (Eawag, SWITZERLAND), Holger Nestler, René Schönenberger, Victor<br />

Nesatyy<br />

P-TUE-312<br />

Genetic Basis Of Proteome Variation In Arabidopsis<br />

Jingyuan Fu (Groningen Bioinformatics Centre, Groningen Biomolecular Sciences<br />

and Biotechnology Institute, University of Groningen, THE NETHERLANDS), Joost<br />

Keurentjes, Twan America, Richard Scheltema, Martijn Dijkstra, Dick Vreugdenhil,<br />

122 123


Proteomics Of Macromolecular Complexes<br />

P-TUE-323<br />

P-TUE-324<br />

P-TUE-325<br />

Analysis Of Nuclear Pore Complex Phosphorylation Sites Using A Maldi-Ltq<br />

Orbitrap Mass Spectrometer<br />

Justin Blethrow (Thermo Fisher Scientific, UNITED STATES), Rosa Viner, Vlad<br />

Zabrouskov, Joseph Glavy<br />

Analyses Of Proteasome Complexes And Proteome Variations In Acute Myeloid<br />

Leukemia Cells<br />

Mariette Matondo, Marie-Pierre Bousquet-Dubouch, Sandrine Uttenweiler-Joseph,<br />

Bernard Payrastre, Stéphane Manenti, Bernard Monsarrat, Odile Burlet-Schiltz<br />

(Institut de Pharmacologie et De Biologie Structurale, Cnrs, FRANCE)<br />

Mapping Human Protein Interaction Networks: The Human Proteotheque<br />

Initiative (Hupi)<br />

Benoit Coulombe (Institut de Recherches Cliniques de Montréal, CANADA), Philippe<br />

Cloutier, Annie Bouchard, Célia Jeronimo, Andrée-Anne Lacombe, Racha Al-Khoury,<br />

Mathieu Lavallée-Adam, Jack Greenblatt, Mathieu Blanchette, Diane Forget<br />

P-TUE-334<br />

P-TUE-335<br />

P-TUE-336<br />

P-TUE-337<br />

Quantitative Analysis Of C/Ebp{Alpha} Transcription Complexes In Leukemia<br />

Rositsa Koleva (Dana-Farber Cancer Institute, UNITED STATES), Scott Ficarro,<br />

Manor Askenazi, Jarrod Marto<br />

Shot-Gun Membrane Proteomics By Acid Hydrolysis Combined With Trypsin And<br />

Chymotrypsin<br />

Joseph Kwon (Proteome Research Team, Korea Basic Science Institute, KOREA),<br />

Jeehyun Oh, Sunghoon Lee, Seung Il Kim, Jong-Soon Choi<br />

Proteomics Study On Human Ccr4-Not: A Multi-Functional Complex Involved In<br />

Mrna Metabolism<br />

Nga-Chi Lau (Umc-Utrecht, THE NETHERLANDS), Annemieke Kolkman, Pim Pijnappel,<br />

Albert Heck, Marc Timmers<br />

Identification Of Protein Phosphorylation Sites Associated With Protein Complex<br />

Assembly Using An Imac-Based Proteomics Procedure<br />

Chang-Hung Lee (Institute of Biochemistry and Molecular Biology, National Yang-<br />

Ming University, TAIWAN)<br />

P-TUE-326<br />

Characterization Of A Novel Subunit Of The Drosophila Melanogaster Chromatin<br />

Remodeling Complex Pbap<br />

Jeroen Demmers (Erasmus Mc, THE NETHERLANDS), Gillian Chalkley, Yuri Moshkin,<br />

Karin Langenberg, Karel Bezstarosti, Andras Blastyak, Henrik Gyurkovics, Peter Verrijzer<br />

P-TUE-338<br />

Molecular Recognition In Oligomeric Enzymes: Integration Of Bioinformatic And<br />

Biosensoric Approaches<br />

Andrey Lisitsa (Institute of Biomedical Chemistry Rams, RUSSIAN FEDERATION), YU<br />

Mezentsev, P Ershov, A Molnar, A Ivanov, A Archakov<br />

P-TUE-327<br />

P-TUE-328<br />

P-TUE-329<br />

Differential Biotinylation To Study Influenza A Polymerase Subunit Pb1<br />

Heterodimerisation<br />

Mathias Dreger (Department of Physiology, Anatomy and Genetics, University of<br />

Oxford, UNITED KINGDOM), Tao Deng, George G. Brownlee<br />

Proteomics Of Protein Complexes: An Approach To Analyze Native Proteomes<br />

Oliver Drews (Department of Physiology, University of California Los Angeles,<br />

UNITED STATES), Yueju Wang, Emily Chen, Jun Zhang, John Yates 3rd, Peipei Ping<br />

Topology And Dynamics Of Protein Interaction Networks That Control Cell Growth<br />

Matthias Gstaiger (Institute of Molecular Systems Biology / Competence Center for<br />

Systems Physiology and Metabolic Diseases, SWITZERLAND), Oliver Rinner, Timo Glatter,<br />

Alexander Wepf, Irena Jevtov, Katja Köhler, Hugo Stocker, Ernst Hafen, Ruedi Aebersold<br />

P-TUE-339<br />

P-tue-340<br />

P-TUE-341<br />

Capture Of The Activated Fc Receptor Complex From The Surface Of Live Cells<br />

By Affinity Receptor Chromatography<br />

John Marshall (Ryerson University, CANADA), Peihong Zhu, Andy Jankowski<br />

Post-Translational Modifications Of The Endogenously Expressed Transcription<br />

Factors Tfiid and Saga<br />

N Mischerikow (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />

University, THE NETHERLANDS), AFM Altelaar, HTM Timmers, WWM Pijnappel, AJR<br />

Heck<br />

Spatiotemporal Changes Of Pka-Akap Complexes In Response To Prostaglandin E2<br />

Nikolaus Oberprieler (Biotechnology Centre of Oslo, University of Oslo, NORWAY),<br />

Thin Thin Aye, Knut Martin Torgersen, Albert Heck, Kjetil Tasken<br />

P-TUE-330<br />

P-TUE-331<br />

Pull-Downs Of Endogenously Expressed, Tagged Proteins For Interactions And<br />

Modifications<br />

Nina Hubner (Max-Planck Institute for Biochemistry, Dep. Proteomic and Signal<br />

Transduction, GERMANY), Johannes Graumann, Michiel Vermeulen, Alexander Bird,<br />

Ina Poser, Matthias Mann<br />

“Tagless” Strategy Of Protein Complex Identification: Towards High Throughput<br />

Jian Jin (Lawrence Berkeley National Laboratory, UNITED STATES), Lee Yang,<br />

Haichuan Liu, Ming Dong, Simon Allan, Steven Hall, Susan Fisher, John-Marc<br />

Chandonia, Mark Biggin, Ewa Witkowska, Peter Walian, Bing Jap, Terry C. Hazen<br />

P-TUE-342<br />

P-TUE-343<br />

Looking For E2f2 Transcription Factor Interacting Proteins<br />

Nerea Osinalde (Department of Biochemistry and Molecular Biology, University of<br />

The Basque Country, SPAIN), Kerman Aloria, Ana Zubiaga, Asier Fullaondo, Jesus M.<br />

Arizmendi<br />

Quantitative Phospho-Proteomics Elucidates Phosphorylation-Dependent<br />

Transcriptional Regulation Of The Yeast Mediator Complex<br />

Gideon Oudgenoeg (Biomolecular Mass Spectrometry and Proteomics Group,<br />

Utrecht University, THE NETHERLANDS), Manuel Tzouros, Joris Benschop, Tony<br />

Miles, Frank Holstege, JeroeN Krijgsveld<br />

P-TUE-332<br />

P-TUE-333<br />

Characterization Of Protein-Complexes Complementing Functional-Genomic<br />

Screens In Human Cell-Lines<br />

Magno Junqueira (Max Planck Institute of Molecular Cell Biology and Genetics -<br />

Dresden, GERMANY), Yusuke Toyoda, Mikolaj Slabicki, Zoltan Maliga, Mirko Theis,<br />

Dragomir Krastev, Frank Buchholz, Antony Hyman, Andrej Shevchenko<br />

Chromatin Proteome Demonstrates System-Wide Response To Replication<br />

Inhibition<br />

Guennadi A. Khoudoli (University of Dundee, UNITED KINGDOM), Peter J. Gillespie,<br />

Graeme X. Stewart, Jens S. Andersen, Jason R. Swedlow, J Julian Blow<br />

P-TUE-344<br />

P-TUE-345<br />

P-TUE-346<br />

Targeting Dynamic Changes Of The Cftr Interactome In Cystic Fibrosis<br />

Sandra Pankow (The Scripps Research Institute, UNITED STATES), Casimir<br />

Bamberger, William Balch, John R. Yates<br />

Cell Cycle Regulation Of Tbp Complexes In Human Cells<br />

Pim Pijnappel (Umc-Utrecht, THE NETHERLANDS), Annemieke Kolkman, Marijke<br />

Baltissen, Albert Heck, Marc Timmers<br />

Examination Of The Protein Complexes Bound On Gal Operon Promoter Of<br />

Thermoanaerobacter Tengcongensis<br />

Zhong Qian (Beijing Genomics Institute, Cas, CHINA), Fan Wei, Li Guo, Siqi Liu<br />

124 125


P-TUE-347<br />

Background Proteins In Immunoprecipitations: What Are They And How To<br />

Reduce Them<br />

Manfredo Quadroni (University of Lausanne, SWITZERLAND), Waridel Patrice,<br />

Bastienne Jaccard, Alexandra Potts<br />

P-TUE-361<br />

Identification Of Putative Complex I Assembly Factors By Blue Native Liquid<br />

Chromatography Ms/Ms<br />

JCT Wessels (Radboud University Nijmegen Medical Center, THE NETHERLANDS),<br />

RO Vogel, LP van den Heuvel, RJ Rodenburg, LG Nijtmans, JAM Smeitink, MH Farhoud<br />

P-TUE-348<br />

P-TUE-349<br />

P-TUE-350<br />

P-TUE-351<br />

P-TUE-352<br />

P-TUE-353<br />

P-TUE-354<br />

P-TUE-355<br />

P-TUE-356<br />

P-TUE-357<br />

P-TUE-358<br />

P-TUE-359<br />

P-TUE-360<br />

Optimized Immunoprecipitation And Co-Immunoprecipitation Using Dynabeads<br />

Elisabeth Breivold, David Gillooly, Paal Songe, Erlend Ragnhildstveit (Invitrogen Dynal<br />

As, NORWAY)<br />

Proteasome Diversity Analysed By Isotope Labelling And Protein Quantitation<br />

Reinout Raijmakers (Biomolecular Mass Spectrometry and Proteomics Group,<br />

Utrecht University, THE NETHERLANDS), Celia Berkers, Annemieke de Jong, Huib<br />

Ovaa, Shabaz Mohammed, Albert Heck<br />

Withdrawn<br />

Withdrawn<br />

Lc-Ms AnalysIs To Identify Ryanodine Receptor 1 (Ryr1) Protein-Protein Interactions<br />

Timothy Ryan (University of Toronto, CANADA)<br />

Quantitative 20s Proteasome Analysis From 5fu-Induced Apoptotic Jurkat T<br />

Cells By Silac, Sds-Page, And 2de Based Analysis<br />

Frank Schmidt (Helmholtz Centre, Leipzig, GERMANY), Alexander Kloos, Martin von<br />

Bergen, Burkhardt Dahlmann, Peter Jungblut, Bernd Thiede<br />

Proteomic Analysis Of Membrane Protein Complexes: Lessons From Affinity-<br />

Purified Ion Channels And Receptors<br />

Uwe Schulte (Logopharm GmbH, GERMANY), Catrin Müller, Wolfgang Bildl, Bernd Fakler<br />

Analysis Of Subunit Composition Of The 20s Proteasome Of Plasmodium Falciparum<br />

Nicole Sessler (Proteome Center Tübingen, University of Tübingen, GERMANY),<br />

Wolfgang Schütz, Rolf Fendel, Benjamin Mordmüller, Peter G. Kremsner, Tobias<br />

Lamkemeyer, Alfred Nordheim<br />

Comparative Mass Spectrometry Of The Endogenously Expressed Nuclear And<br />

Cytoplasmic Exosome<br />

Silvia Synowsky (Utrecht University, THE NETHERLANDS), Reinout Raijmakers, Albert Heck<br />

Identification Of Intracellular Molecules Interacting With The Stress-Induced,<br />

Psoriasis Susceptibility-Related Non-Coding Rna, Prins<br />

Krisztina Szegedi (Department of Dermatology and Allergology, University of<br />

Szeged, Hungary), Mária Antal, István Németh, Zsuzsanna Bata-Csörgõ, Attila<br />

Dobozy, Lajos Kemény, Márta Széll<br />

A Quantitative Proteomics Approach To Reveal Dynamics In Transcription Factor<br />

Complexes<br />

Marc Timmers (University Medical Centre Utrecht, THE NETHERLANDS), Florence<br />

Mousson, Petra de Graaf, Annemieke Kolkman, Pim Pijnappel, Bart Gevers<br />

Proteomic Analysis Of Ubxd1: Identification Of Novel Interaction Partners<br />

Julian Vasilescu (Ottawa Institute of Systems Biology, University of Ottawa,<br />

CANADA), Daniel Zweitzig, Dale Haines, Daniel Figeys<br />

Quantification Of Protein Complex Components In Interaction Networks<br />

Alexander Wepf (Institute for Molecular Systems Biology / Competence Center for<br />

Systems Physiology and Metabolic Diseases, SWITZERLAND), Timo Glatter, Ruedi<br />

Aebersold, Matthias Gstaiger<br />

P-TUE-362<br />

Contrasting Proteome Biology And Functional Heterogeneity Of The 20s<br />

Proteasome Complexes<br />

Glen Young (University of California, Los Angeles, united states), Aldrin Gomes,<br />

Yueju Wang, Peipei Ping<br />

Yeast Proteomics; Sparks For New Biology<br />

P-TUE-363<br />

P-TUE-364<br />

P-TUE-365<br />

P-TUE-366<br />

P-TUE-367<br />

P-TUE-368<br />

P-TUE-369<br />

P-TUE-370<br />

A New Approach To Achieving A Fast, In-Depth Biological Overview Of Yeast<br />

Proteomics Data<br />

Morten Bern (Proxeon A/S, DENMARK), John Chakel, Ole Vorm<br />

Comprehensive Curation And Analysis Of Global Interaction Networks<br />

Lorrie Boucher (Samuel Lunenfeld Research Institute, Toronto, CANADA), Teresa<br />

Reguly, Bobby-Joe Breitkreutz, Chris Stark, Rose Oughtred, Michael Livstone,<br />

Ashton Breitkreutz, Valerie Wood, Kara Dolinski, Mike Tyers<br />

Interrogation Of The Tor Signaling Network In Budding Yeast<br />

Ashton Breitkreutz (Samuel Lunenfeld Research Institute, Toronto, CANADA), Jeff<br />

Sharom, Brett Larsen, Zhen-Yuan Lin, Lorrie Boucher, Anne-Claude Gingras, Mike Tyers<br />

Cystein Modification In Response To Photoinduced Oxidative Stress In<br />

Saccharomyces Cerevisiae<br />

Audrey Combes (Institut Jacques Monod, FRANCE), Jean Michel Camadro<br />

Changing Profiles Of Mannose-1-Phosphate Guanyltransferase (Psa1) Interacting<br />

Proteins During Batch Culture<br />

Ville Parviainen (Haartman Institute, FINLAND), Sakari Joenväärä, Pirkko Mattila,<br />

Risto Renkonen<br />

Analysis Of Basal And Activated Pre-Initiation Complexes With Itraq Based<br />

Proteomics<br />

Timothy Sikorski (Harvard Medical School, UNITED STATES), Scott Ficarro, Jignesh<br />

Parikh, Manor Askenazi, Stephen Buratowski, Jarrod Marto<br />

A Modular Network Regulates Longevity In Yeast<br />

Vladimir Titorenko (Concordia University, Biology Department, CANADA)<br />

Differential Expression Proteomics Of A Yeast Mutant With Low 14-3-3 Protein<br />

Activity.<br />

Paul van Heusden (Institute of Biology, Leiden University, THE NETHERLANDS)<br />

126 127


Poster Listing<br />

Wednesday 20 august<br />

Array Based Proteomics<br />

P-WED-001<br />

P-WED-002<br />

P-WED-003<br />

The Proteomic Landscape Of In Vitro Growth: A Comparative Analysis Using<br />

Antibody-Based Proteomics<br />

Sara Strömberg, Anna Asplund (Uppsala University, SWEDEN), Linn Fagerberg, Adila<br />

Elobeid, Marcus Gry, Kenneth Nilsson, Peter Nilsson, Rebecca Rimini, Mathias Uhlen,<br />

Fredrik Ponten<br />

Hyphenation Of Surface Plasmon Resonance Imaging To MALDI Mass<br />

Spectrometry By On-Chip MALDI MS Analysis<br />

Sophie Bellon (Genoptics, Orsay France, FRANCE), William Buchmann, Florence<br />

Gonnet, Nathalie Jarroux, Marielle Anger-Leroy, Regis Daniel<br />

Antibody Microarray Scan Of 725 Antibodies To Identify Biomarkers Of<br />

Radioresistance<br />

Laura Smith, Omar Qutob, Mark Watson, Andrew Beavis, Michael Lind, Philip Drew,<br />

Lynn Cawkwell (University of Hull, UNITED KINGDOM)<br />

P-WED-012<br />

P-WED-013<br />

P-WED-014<br />

P-WED-015<br />

Anti-Angiogenic Effect Of A Cell Permeable Peptide, P11, On Huvec<br />

Proliferation Via Analysis Of Differential Protein Expression Profiling Using<br />

ProteoChip-Based Antibody Microarray.<br />

In-Cheol Kang (Department of Biological Science, Biochip Research Center, Hoseo<br />

University, KOREA)<br />

Development Of Screening Method Of Breast Cancer Based On Multiple Serum<br />

Proteins Using Diagnostic Algorithm<br />

Byoung-Kwon Kim (Department of Pathology, Seoul National University Hospital,<br />

KOREA), Chul Woo Kim, Dong-Young Noh, Jong Won Lee, Pil Je Park<br />

Protein Microarrays As Tool For The Quantitative Analysis Of Signal<br />

Transduction In Tumor Samples<br />

Ulrike Korf (Molecular Genome Analysis, German Cancer Research Center,<br />

GERMANY), Christian Löbke, Frauke Henjes, Heiko Mannsperger, Christian Schmidt,<br />

Holger Sültmann<br />

Dub-1, A Fate Determinant Of Dynein Heavy Chain In B-Lymphocytes, Is<br />

Regulated By The Ubiquitin-Proteasome Pathway<br />

Min-Young Lee (Cell and Gene Therapy Research Institute, Graduate School of Life<br />

Science and Biotechnology, Pochon Cha University, Cha General Hospital, KOREA),<br />

Brijesh S. Ajjappala, Myung-Sun Kim, Suresh Ramakrishna, YU-Kyoung Oh, Kwang-<br />

Hyun Baek<br />

P-WED-004<br />

P-WED-005<br />

P-WED-006<br />

P-WED-007<br />

Withdrawn<br />

An Automated Quantitative Platform For The Analysis Of Biomarkers In Tissue<br />

Jason Christiansen (Historx, UNITED STATES), Mark Gustavson, Robert Pinard,<br />

Jane Mayotte, Brian Bourke, Wendy Davis<br />

Cladribine And Fludarabine Induce Proteomic Changes In B-Lymphoproliferative<br />

Disorders<br />

Richard Christopherson (School of Molecular and Micobial Biosciences, University<br />

of Sydney, AUSTRALIA), Swetlana Gez, Carlos Cassano, Stephen Mulligan, Larissa<br />

Belov, Pauline Huang<br />

Multiplexing Immunoassay Platforms: Are They Appropriate For The Biomarker<br />

Discovery Pipeline?<br />

Qin Fu (Johns Hopkins University, Department of Medicine, Bayview Proteomics<br />

Center, UNITED STATES), Jennifer van Eyk<br />

P-WED-016<br />

P-WED-017<br />

P-WED-018<br />

P-WED-0<strong>19</strong><br />

Establishing A High Throughput Platform For Constructing Monoclonal Antibody Bank<br />

Ching-Yu Lin (Graduate Institute of Applied Science and Engineering, Catholic Fu-Jen<br />

University, TAIWAN), Jen-Chieh Lee, Han-Min Chen<br />

Novel Method For Detection Of Activated Transcription Factors In Human<br />

Gestational Tissues<br />

Karen Oliva (Translational Proteomics, Baker Heart Research Institute, AUSTRALIA),<br />

Martha Lappas, Gillian Barker, Greg Rice<br />

MALDI-Ms Readable Protein Arrays<br />

Richard Goodwin, Ekaterina Mckenna, Andrew Pitt (Institute of Biomedical and Life<br />

Sciences, University of Glasgow, UNITED KINGDOM)<br />

Mapping The Human Proteome - A Comprehensive In Situ Analysis Of Protein<br />

Profiles In Normal And Cancer Cells<br />

Fredrik Ponten (Uppsala University, SWEDEN)<br />

P-WED-008<br />

P-WED-009<br />

P-WED-010<br />

P-WED-011<br />

Celluspots Peptide Arrays For Immunodiagnosis And Kinase Profiling<br />

Heinrich Gausepohl (Intavis Bioanalytical Instruments Ag, GERMANY), Evelyn<br />

Rossmann, Ole Brandt, Reinhard Wallich<br />

Large Scale Comperative Rna And Protein Expression Analysis<br />

Marcus Gry (Dept of Proteomics, SWEDEN)<br />

Generation Of Phosphorylation Profiles For Cancer Biomarker Research On<br />

Peptide Microarrays<br />

Riet Hilhorst (Pamgene International Bv, THE NETHERLANDS), Liesbeth Houkes,<br />

Adriënne van Denberg, Rob Ruijtenbeek<br />

Nanobiochips For Proteomics And Diagnostics<br />

Yury Ivanov (Institute of Biomedical Chemistry Rams, RUSSIAN FEDERATION), S<br />

Nikitina, T Pleshakova, A Ivanov, A Kaysheva, P. Frantsuzov, A Archakov<br />

P-WED-020<br />

P-WED-021<br />

P-WED-022<br />

P-WED-023<br />

Multiparametric Protein Analyses From Core Needle Biopsies Of Primary Breast<br />

Cancer Lesions<br />

Thomas Joos, Nicole Schneiderhan-Marra (Nmi Natural and Medical Sciences<br />

Institute at the University of Tubingen, GERMANY), Cornelia Kazmaier, Karin Koretz,<br />

Georg Sauer, Rainer Muche, Helmut Deissler<br />

Profiling Cancer Proteomes With Complex Antibody Microarrays<br />

Christoph Schroeder (German Cancer Research Center, Functional Genome<br />

Analysis, GERMANY), Alexandra Nieters, Sven Rueffer, Jakob Linseisen, Kurt<br />

Fellenberg, Joerg D. Hoheisel<br />

Peptide Microarrays For Immune Monitoring And Biomarker Discovery<br />

Mike Schutkowski (Jpt Peptide Technologies GmbH, GERMANY)<br />

Antibody Suspension Bead Arrays – An Application For Serum And Plasma<br />

Analysis Within Antibody Proteomics<br />

Jochen Schwenk (Department of Proteomics, School of Biotechnology, Kth – Royal<br />

Institute of Technology, SWEDEN), Marcus Gry, Rebecca Rimini, Mathias Uhlén,<br />

Peter Nilsson<br />

128 129


P-WED-024<br />

P-WED-025<br />

P-WED-026<br />

P-WED-027<br />

P-WED-028<br />

Biomarkers Iii<br />

P-WED-029<br />

P-WED-030<br />

P-WED-031<br />

P-WED-032<br />

P-WED-033<br />

P-WED-034<br />

P-WED-035<br />

Profiling Post-Translational Modification Activity In Complex Biological Mixtures<br />

Using Protein Microarray Technology<br />

Charles Spruck (Sidney Kimmel Cancer Center, UNITED STATES), Sonia del Rincon,<br />

Jeff Rogers<br />

An Antibody-Based Proteomics Approach To Identify Diagnostic And Prognostic<br />

Markers In Malignant Melanoma<br />

Sara Stromberg (Dept of Genetics and Pathology, Uppsala University, SWEDEN),<br />

Margret Agnarsdottir, Anna Asplund, Fredrik Ponten<br />

Production Of Hen Egg Yolk Antibodies (Igy) To Human Plasma Proteins<br />

Sock Hwee Tan (Dept of Chemistry and Biomolecular Sciences, Macquarie University,<br />

AUSTRALIA), Amit Kapur, Veronika Polaskova, Wai-Kei Shum, Mark Baker<br />

Tracing Pathway Activities With Kinase Inhibitors And Reverse Phase Protein<br />

Arrays<br />

Jan van Oostrum (Zeptosens, SWITZERLAND), Markus Ehrat, Hans Voshol<br />

Preprocessing And Normalization Of Protein Array Data For Biomarker Discovery<br />

Zhen Zhang (Ctr for Biomarker Discovery, Johns Hopkins School of Medicine, UNITED<br />

STATES), Yan Li, C Nicole Rosenzweig, Lori Sokoll, Xiaer Sun, Katherine Osborne,<br />

Autumn Breaud, Daniel W. Chan<br />

Identification Of Proteomic-Specific Profiles In Patients With Fibrocystic Breast<br />

Disease<br />

Milena Saccomanno (Lab. of Proteomics and Ms, Magna Graecia University of<br />

Catanzaro, ITALY), Domenica Scumaci, Marco Gaspari, Pierosandro Tagliaferri,<br />

Francesco Boccardo, Giovanni Cuda<br />

Tissue Proteomics Of Ovarian Cancer<br />

Michel Salzet (MALDI Imaging Team, FRANCE), Mohamed El Ayed, Amélie -Laure<br />

Jacquet, Pierre Collinet, Jean-Philippe Lucot, Denis Vinatier, Isabelle Fournier<br />

Proteomic Analysis Evidenced Cd148 As A New Biomarker For Mantle Cell<br />

Lymphoma Diagnosis<br />

Laurent Miguet, Luc Fornecker, Raoul Herbrecht, Sarah Sanglier-Cianférani (Cnrs-<br />

Iphc-Dsa-Lsmbo, FRANCE), Alain van Dorsselaer, Laurent Mauvieux<br />

Early Detection Of Oral Precancer Using Protein Biomarkers<br />

Tieneke Schaaij-Visser (University of Utrecht, THE NETHERLANDS), Ruud<br />

Brakenhoff, Albert Heck, René Leemans, Monique Slijper<br />

A Novel Validated Protein Signature For Prostate Cancer Diagnosis<br />

Ralph Schiess (Institute of Molecular Systems Biology / Competence Center for<br />

Systems Physiology and Metabolic Disease, SWITZERLAND), Igor Cima, Silke Gillessen,<br />

Vinzenz Lange, Arnoud Templeton, Thomas Cerny, Wilhelm Krek, Ruedi Aebersold<br />

Urinary Proteomic Biomarkers In Coronary Artery Disease<br />

Eric Schiffer (Mosaiques Diagnostics and Therapeutics Ag, GERMANY), Lukas U.<br />

Zimmerli, Janet K. Snell-Bergeon, David M. Maahs, Harald Harald Mischak, Anna F.<br />

Dominiczak<br />

Analysis Of The Immune System: Whole Blood Stimulation Assays And Multi-<br />

Analyte Profiling<br />

Thomas Joos, Nicole Schneiderhan-Marra, Mike SpaIn, Jim Mapes, Sonja Volk (Nmi<br />

Natural and Medical Sciences Institute at the University of Tubingen, GERMANY),<br />

Marion Schneider, Manfred Schmolz<br />

P-WED-036<br />

P-WED-037<br />

P-WED-038<br />

P-WED-039<br />

P-WED-040<br />

P-WED-041<br />

P-WED-042<br />

P-WED-043<br />

P-WED-044<br />

P-WED-045<br />

P-WED-046<br />

P-WED-047<br />

Identification Of Differentially Expressed Proteins In Breast Cancer Subtypes By<br />

Dige And MALDI-TOFms<br />

Daniela Schulz (Institute of Pathology, Helmholtz Zentrum München, German<br />

Research Center for Environmental Health, GERMANY), Claudia Böllner, Ulrike Reich,<br />

Gerry Thomas, Heinz Höfler, Michaela Aubele<br />

Annexin A3 In Urine: A Novel Biomarker For Prostate Cancer Superior To Psa<br />

Gerhard Schwall (Proteosys Ag, GERMANY), Slobodan Poznanovic, Karlfried Groebe,<br />

Martin Schostak, Markus Müller, Helmut Klocker, Joerg Hennenlotter, Susan<br />

Feyerabend, Arnulf Stenzel, Andre Schrattenholz<br />

Comparative Analysis Of Intestinal Epithelial Cells’ Secretome And Exosomes<br />

Irmgard Schwarte-Waldhoff (University of Bochum, Med. Clinic, Imbl, GERMANY),<br />

Susanne Klein-Scory, Hanna Diehl, Christian Stephan, Katja Kuhlmann, Andrea<br />

Tannapfel, Kai Stühler, Helmut MeYer, Wolff Schmiegel, Bettina Warscheid<br />

Transcriptomic And Proteomic Analysis Of Liver Cancer In Hbx Tg Mice<br />

Je Kyung Seong (Seoul National University, KOREA), Yu Hee Lee, Sae Jin Oh, Kyung<br />

Jin Roh, Dae Yul Yu<br />

New Protein Biomarkers That Distinguish Between Aggressive And Indolent<br />

Chronic Lymphocytic Leukemia<br />

Zhouxin Shen (Cell and Developmental Biology, University of California, UNITED<br />

STATES), Han-Yu Chuang, Laura Z. Rassenti, Thomas J. Kipps, Steven P. Briggs<br />

Maximizing Technical Reproducibility By Multi-Instrument Alignment Allows<br />

In-Depth And Timely Proteomic Analysis Of Large Cohort Of Clinical Samples:<br />

Kidney Function<br />

Simon Sheng (Johns Hopkins University, UNITED STATES), Andrew Meng, Helena<br />

Skalnikova, Qin Fu, Jie Zhu, Jennifer van Eyk<br />

MALDI-TOF Ms Is Perspective Method For Profiling Biomarkers Bound To<br />

Albumine To Detection Lung Cancer<br />

Valeriy Shevchenko (N.N. Blokhin Russian Cancer Research Center, RUSSIAN<br />

FEDERATION), Natalia Arnotskaya, David Zaridze<br />

Quantitative Proteomics Study Of Breast Cancer Cell Lines Isolated From A<br />

Single Patient<br />

Qian Shi (Fudan University, CHINA), Bo Gu, Xiaoen Xu, Meng Qiao, Ping Wei, Yinghua<br />

Jiang, Jing Lu<br />

Targeted Proteomics Of Rat Liver Preneoplastic Lesions Using Laser Capture<br />

Microdissection Coupled With iTRAQ® Reagents<br />

Takeshi Shibata (Applied Biosystems Japan Ltd, JAPAN), Anna Kakehashi, Masayo<br />

Inoue, Masato Aoshima, Mayumi Shindo, Kenichi Kudo, Takuichi Tsubata, Sumie Ando,<br />

Hideki Wanibuchi<br />

Study Of Lysozyme / Lipocalin Ion Ratio In Tear With Age By MALDI-TOF<br />

Jentaie Shiea, Li-Hua Lo (National Sun Yat-Sen University, TAIWAN)<br />

Rapidly Screening Of Albuminuria Using Matrix-Assisted Laser Desorption<br />

Ionization/Time-Of-Flight Mass Spectrometry<br />

Jentaie Shiea, Huan-Yao Wang (Department of Chemistry, National Sun Yat-Sen<br />

University, TAIWAN), Yi-Tzu Cho, Li-Hua Lo, Deng-Chyang Wu, Min-Zong Huang<br />

Rapid Diagnosis Of Hematuria And Hemoglobinuria Using Matrix-Assisted Laser<br />

Desorption Ionization/Time-Of-Flight Mass Spectrometry<br />

Jentaie Shiea, Yi-Hsuan Chen (National Sun Yat-Sen University, TAIWAN), Li-Hua Lo,<br />

Deng-Chyang Wu, Min-Zong Huang<br />

130 131


P-WED-048<br />

P-WED-049<br />

P-WED-050<br />

P-WED-051<br />

P-WED-052<br />

P-WED-053<br />

P-WED-054<br />

P-WED-055<br />

P-WED-056<br />

P-WED-057<br />

Rapid Detection Of Hemoglobins As Ischemic Stroke Biomarkers In Serum By<br />

Mass Spectrometry<br />

Jentaie Shiea, Poyin Huang (Department of Neurology, Kaohsiung Medical University<br />

Chung-Ho Memorial Hospital, Kaohsiung Medical Univ., TAIWAN), Li-Hua Lo, Ching-<br />

Kuan Liu, Yi-Hsuan Chen<br />

Development Of Novel Biomarkers For Breast Cancer In North Indian Population<br />

Yogeshwer Shukla (Indian Institute of Toxicolgy Research, Lucknow, INDIA), Jasmine<br />

George, Preeti Roy, Pranav Chaturvedi, Shailendra Kumar, Sandeep Kumar<br />

Cyclic Abundant Plasma Immuno-Depletion (Capi)<br />

Wai-Kei Shum (Dept of Chemistry and Biomolecular Sciences, Macquarie University,<br />

AUSTRALIA), Amit Kapur, Veronika Polaskova, Sock-Hwee Tan, Mark Baker<br />

Novel Urinary Peptidomic Analysis For Acute Rejection Monitoring For Renal<br />

Transplants<br />

Tara Sigdel (Stanford University Medical School, UNITED STATES), Xuefeng Ling, Ken<br />

Lau, Irwin Lau, James Schilling, Minnie Sarwal<br />

Seppro® Fractionation Platform For Enhanced Detection Of Biomarkers In<br />

Biofluids.<br />

Sergey Sikora (Genway Biotech, Inc., UNITED STATES), Xiangming Fang, Li Deng,<br />

Matthew Landry, Wei-Wei Zhang<br />

Withdrawn<br />

Proteome Characterization Of Healthy And Asthmatic Nasal Epithelium Cells<br />

Tania Simoes (Insa, I.P., PORTUGAL), Fatima Vaz, Antonio Bugalho Almeida, Timothy<br />

Veenstra, Josip Blonder, Deborah Penque<br />

Markers For Assault - Proteomics And Forensic Science In New Zealand<br />

Joanne Simons (Forensic Biology Group, Esr (Institute of Environmental and<br />

Scientific Research), NEW ZEALAND), Sue Vintiner, Penny Truman, Danny Kay, Kelly<br />

Atkinson<br />

Prognostic Significance Of Head-And-Neck Cancer Biomarkers Previously<br />

Discovered And Identified Using iTRAQ-Labeling And Multidimensional Liquid<br />

Chromatography – Tandem Mass Spectrometry<br />

KW Michael Siu (York University, CANADA), Ajay Matta, Nootan Kumar Shukla,<br />

Siddhartha D. Gupta, Ranju Ralhan<br />

Stabilization Of Proteins And Peptides And Identification Of Peptides In<br />

Pancreatic Tissue<br />

Karl Sköld (Denator Ab, SWEDEN), Céline Fernandez, Sofia Waldemarson, Roberto<br />

Stella, Mikhail Savitski, Marcus Svensson, Mats Borén, Roman Zubarev, Per E.<br />

Andrén, Peter James<br />

P-WED-061<br />

P-WED-062<br />

P-WED-063<br />

P-WED-064<br />

P-WED-065<br />

P-WED-066<br />

P-WED-067<br />

P-WED-068<br />

P-WED-069<br />

P-WED-070<br />

Withdrawn<br />

Multiple Sclerosis Related Proteins In Csf Identified By Advanced Mass Spectrometry<br />

Marcel Stoop (Department of Neurology, Erasmus University Medical Centre, THE<br />

NETHERLANDS), Lennard Dekker, Mark Titulaer, Peter Burgers, Peter Sillevis<br />

Smitt, Theo Luider, Rogier Hintzen<br />

Sample Preparation For Molecular Histology<br />

Martin Schürenberg (Bruker Daltonics, GERMANY), Gongyi Shi, Rolf Müller, Sören O.<br />

Deininger, Detlev Suckau<br />

Effect Of 50-Hz Magnetic Fields On Proteome Of Human Sh-Sy5y<br />

Neuroblastoma Cells<br />

Marilisa Sulpizio (Department of Biomedical Science, Excellent Center on Aging<br />

Studies, ITALY), Stefano Falone, Enrica Eleutero, Fabrizio di Giuseppe, Alessandro<br />

Mirabilio, Fernanda Amicarelli, Carmine di Ilio, Stefania Angelucci<br />

A Dynamic Urinary Proteomic Analysis Reveals Stable Proteins May Be Used As<br />

A Source Of Potential Biomarker<br />

Wei Sun (Department of Pathophysiology, Proteomics Research Center, Institute<br />

of Basic Medical Sciences, Chinese Academy of Medical Sciences / Peking Union<br />

Medical College, CHINA)<br />

Serum Amyloid A As A Serum Biomarker For The Detection Of Lung Adenocarcinoma<br />

Hye-Jin Sung (Department of Biochemistry, School of Dentistry Kyungpook National<br />

Univ., KOREA), Jung-Mo Ahn, Jae-Young KIm, Jae-Yong Park, Je-Yoel Cho<br />

A Novel Approach For Biomarker Discovery In Colorectal Cancer<br />

Silvia Surinova (Institute of Molecular Systems Biology / Life Science Zürich Phd<br />

Program ‘Systems Biology of Complex Diseases’ of The Competence Center for<br />

Systems Physiology and Metabolic Disease, SWITZERLAND), Bruno Domon, Marian<br />

Hajdúch, Ruedi Aebersold<br />

Peptidomic Analysis Of Serum And Dialysate In Hemodialysis Patients<br />

Kenji Tanaka (Protosera, Inc., JAPAN), Lyang-Ja Lee, Yoshihiro Motomiya, Ikurou<br />

Maruyama<br />

Csf Proteomics To Identify Candidate Biomarkers For Multiple Sclerosis<br />

Charlotte Teunissen (Vu University Medical Center Amsterdam, Department of<br />

Molecular and Cellular Biology and Immunology, THE NETHERLANDS), Marleen Koel-<br />

Simmelink, Thang Pham, Laura van der Voort, Connie Jimenez<br />

Als Biomarker Discovery In Cortex Samples By MALDI-TOF, MALDI Imaging, And<br />

MALDI-Ftms<br />

Kristin Boggio, Long Li, Michael L. Easterling, Christopher J. Thompson (Bruker<br />

Daltonics Inc., UNITED STATES), Nathalie Y.R. Agar, Jeffrey N. Agar<br />

P-WED-058<br />

P-WED-059<br />

P-WED-060<br />

Global Shotgun Proteomic Analysis Of Colorectal Carcinoma<br />

Robbert Slebos (Vanderbilt University, UNITED STATES)<br />

Proteomics Of Sepsis<br />

Afonso Soares (Protein Chemistry Laboratory, Dept of Biochemistry, Institute of<br />

Chemistry, Ufrj/ Rio de Janeiro Proteomics Network, BRAZIL), Marise Santos,<br />

Monique Trugilho, Ana Ferreira, Jonas Perales, Gilberto Domont<br />

Proteomic Analyses Of Retina Of Excitatory Amino Acid Carrier 1 (Eaac1)-<br />

Deficient Mice<br />

Nazariy Souchelnytskyi (Karolinska Biomics Center, SWEDEN)<br />

P-WED-071<br />

P-WED-072<br />

P-WED-073<br />

Identification And Quantification Of Tear Proteins In Sjogren’s Syndrome<br />

Naohisa Tomosugi (Kanazawa Medical University, JAPAN), Kazuko Kitagawa, Hideyuki<br />

Tsuchida, Masato Higuchi<br />

Serum Proteome Analysis Of Patients With Hodgkin’s Lymphoma<br />

Thanh Tran (Institute of Biotechnology (Ibt), Vietnam), Chi Phan<br />

Prognostic Biomarker In Esophageal Cancer By 2d-Dige, Tumor Tissues And<br />

Clinical Data<br />

Norihisa Uemura (Proteome Bioinformatics Project, National Cancer Center Research<br />

Institute / Division of Esophageal Surgery, National Cancer Center Hospital / Division<br />

of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine,<br />

JAPAN), Yukihiro Nakanishi, Hoichi Kato, Masato Nagino, Setsuo Hirohashi, Tadashi Kondo<br />

132 133


P-WED-074<br />

Identification Of A Tamoxifen Response Protein Profile In Breast Cancer By<br />

Nanolc-Fticr Ms<br />

Arzu Umar (Erasmus Mc Rotterdam, THE NETHERLANDS)<br />

P-WED-087<br />

Measuring Protein Synthesis As Part Of Proteomics Study On Cancer Cell Proliferation<br />

Gary Guishan Xiao (Genomics & Functional Proteomics Lab/Orc at Creighton University,<br />

UNITED STATES), Yingchun Zhao, Shu Lim, Jing Xiao, Robert Recker, Wai-Nang Paul Lee<br />

P-WED-075<br />

P-WED-076<br />

P-WED-077<br />

P-WED-078<br />

Addressing Systematic Factors Affecting Ms Molecular Biomarker Discovery<br />

Andrea Urbani (University of Chieti and Pescara / Irccs-Santa Lucia, ITALY),<br />

Damiana Pieragostino, Piero del Boccio, Francesca Petrucci, Dante Mantini, Barbara<br />

Pavone, Valeria Marzano, Federica Forli, Carmine di Ilio, Giorgio Federici<br />

Sarcoidosis Specific Biomarkers Detection In Bronchoalveolar Lavage 2d<br />

Proteomes For The Early Diagnosis Of The Disease<br />

María Uribarri (Proteomika S.L., SPAIN), Hannelore Kothmaier, Susanna Petzmann,<br />

Alberto Monasterio, José Riera, Daniel Nagore, Laureano Simón, Antonio Martinez,<br />

Helmut Popper<br />

Identification Of Carboxymethyl Lysine Modified Serum Proteins From Diabetic Patients<br />

Meeme Utt (University of Tartu, ESTONIA)<br />

Segment-Specific Analysis And Quantitation Of The Mouse Nephron Proteome<br />

Ana Velic (Max-Planck Institute of Biochemistry, GERMANY), Boris Macek, Jürgen<br />

Cox, Florian Gnad, Maria Lecca, Andre Brändli, Johannes Loffing, Nicolas Picard,<br />

Carsten Wagner, Matthias Mann<br />

P-WED-088<br />

P-WED-089<br />

P-WED-090<br />

P-WED-091<br />

Identificating Nm23-H1 As A Metastasis-Promoting Factor In Nasopharyngeal<br />

Carcinoma By Proteomic Analysis<br />

Zhi-Qiang Xiao (Key Laboratory of Cancer Proteomics of Chinese Ministry of Health,<br />

Xiangya Hospital, Central South University, CHINA), Bin Yi, Mao-Yu Li, Peng-Fei<br />

Zhang, Cui Li, Zhu-Chu Chen<br />

Identificating Cathepsin D As A Biomarker For Differentiation And Prognosis Of<br />

Nasopharyngeal Carcinoma By Laser Capture Microdissection And Proteomic<br />

Analysis<br />

Bin Yi (Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya<br />

Hospi, CHINA), Ai-Lan Cheng, Wei-Guo Huang, Zhu-Chu Chen, Zhi-Qiang Xiao<br />

Changes In Levels Of Prostaglandin D2 Metabolite In Cerebrospinal Fluids Of<br />

Rheumatoid Patients<br />

Yukio Yamamoto (Tokyo Metropolitan Institute of Medical Science, JAPAN), Mariko<br />

Shimamura, Yoshiko Akiota, Hiroshi Sato, Susumu Fukasaku, Kosuke Aritake<br />

Withdrawn<br />

P-WED-079<br />

Identification Of Biomarkers For Depression-Like Behavior In A Mouse Model<br />

Christian Webhofer (Max Planck Institute of Psychiatry, GERMANY), Yuji Odagaki,<br />

Birgit Bisle, Elisabeth Frank, Melanie Keßler, Katrin Haegler, Giuseppina Maccarrone,<br />

Boris Hambsch, Rainer Landgraf, Christoph W. Turck<br />

P-WED-092<br />

Cross-Link Of Proteome With Transcriptome For Metastasis Hcc<br />

Pengyuan Yang (Institutes for Biomedical Sciences and Research Institute For Liver<br />

Cancer, Fudan University, CHINA), Huali Shen, Fan Zhong, Yang Zhang, Yinkun Liu,<br />

Fuchu He<br />

P-WED-080<br />

P-WED-081<br />

P-WED-082<br />

Quantitative Proteomic Analysis Of Hsp90 Modulation Using iTRAQ-Based<br />

Online Three-Dimensional Nlc-Esi-Cid-Pqd-Ms/Ms<br />

Jing Wei (Biogen Idec Corp., UNITED STATES), Ben Colson, Mark J. Daniels, Diem<br />

Tran, Noel Timple, Naveen Dakappagari, Shabnam Tangri, Steve French, Karen<br />

Lundgren, Alex Buko<br />

Comparative Proteomic Biomarkers Analysis Of Human Brain Tumors<br />

Ching-Yi Weng (Institute of Basic Medical Science, College of Medicine, National<br />

Cheng-Kung University, TAIWAN), Kuo-Chen We, Tsuey-Yu Chang, Chia-Haw Huang,<br />

Jung-Hsien Chiang, Petrus Tang, Jyh-Wei Shin<br />

Diagnosis Of Ovarian Cancer By Mass Spectrometry – Getting Closer?<br />

Mikkel West-Nørager (Statens Serum Institut, DENMARK), Rasmus Bro, Estrid<br />

Høgdall, Claus Høgdall, Lotte Nedergaard, Niels H.H. Heegaard<br />

P-WED-093<br />

P-WED-094<br />

P-WED-095<br />

Autoantibody To Tumor Antigen, Alpha 2-Hs Glycoprotein: A Novel Biomarker Of<br />

Breast Cancer<br />

Jae Kyo Yi (Cancer Institute, Seoul National University College of Medicine, KOREA),<br />

Jong Wook Chang, Wonshik Han, Jong Won Lee, Myeong-Hee Yu, Dong-Young Noh<br />

Comprehensive Analysis Of Cell-Cycle-Associated Biomarkers Induced By Genistein<br />

Kenichi Yoshida (Meiji University, JAPAN)<br />

Proteomic Profiling Of Human Lymphatic Endothelial Cells For Analyzing<br />

Lymphangiogenesis<br />

Yasunobu Yoshida (Laboratory of Pharmaceutical Proteomics, National Institute of<br />

Biomedical||Innovation (Nibio)/ Graduate School of Pharmaceutical Sciences, Osaka<br />

University, JAPAN), Sunao Imai, Tomoaki Yoshikawa, Haruhiko Kamada, Shin-Ichi<br />

Tsunoda, Yasuo Tsutsumi<br />

P-WED-083<br />

Early Protein Biomarkers Associated With Experimentally Induced Gastric<br />

Cancer In Rats<br />

Lam Wing Kei (The Proteomic Task Force, Department of Applied Biology and<br />

Chemical Technology, The Hong Kong Polytechnic University, CHINA)<br />

P-WED-096<br />

Identification Of The Potential Biomarkers For Prostate Cancer From Tears And Sera<br />

Jingjing You (University of New South Wales / Minomic Pty Ltd, AUSTRALIA), Anna<br />

Fitzgerald, Paul J. Cozzi, Zhenjun Zhao, Pamela J. Russell, Bradley J. Walsh, Mark<br />

Willcox, Yong Li<br />

P-WED-084<br />

P-WED-085<br />

P-WED-086<br />

Serum Protein Profiling Of Sle Using Recombinant Antibody Microarrays<br />

Christer Wingren (Lund University, SWEDEN)<br />

Proteomic Serum Profiling For Analyzing The Individual Risk For Endometriosis<br />

Monika Wölfler (Rwth Aachen University, Department of Obstetrics and Gynecology,<br />

GERMANY), Daniela Otten, Corinna Henkel, Ruth Knüchel-Clarke, Werner Rath,<br />

Kristina Schwamborn<br />

Proteomic And Bioinformatic Analysis Of Cancer-Cell Secretome For Biomarker<br />

Identification<br />

Chih-Ching Wu (Proteomics Core Laboratory / Molecular Medicine Research Center,<br />

Chang Gung University, TAIWAN), Chia-Wei Hsu, Chi-De Chen, Jau-Song Yu<br />

P-WED-097<br />

P-WED-098<br />

P-WED-099<br />

Withdrawn<br />

Biomarker Screening Using Feature Selection And Analysis Framework<br />

Su-Jun Li (Shanghai Institutes for Biological Sciences, CHINA), Rong-Xia Li, Wei-Ping<br />

Jia, Yi-Xue Li, Jia-Rui Wu, Rong Zeng<br />

Proteome Analysis Of Mouse Lung Cancer Cmt Cell Lines<br />

Kelan Zhang (Protein Research Group, Dept. of Biochemistry and Molecular Biology,<br />

University of Southern Denmark, DENMARK), Krzysztof Wrzesinski, Stephen J. Fey,<br />

Peter Mose Larsen, Xumin Zhang, Peter Roepstorff<br />

134 135


P-WED-100<br />

P-WED-101<br />

Biomarker Discovery In Brain And Plasma Of A Mouse Model Of Trait Anxiety<br />

Y Zhang (Max Planck Institute f Psychiatry, GERMANY), Md Filiou, B Bisle, E Frank,<br />

Ms Ksssler, K Haegler, G Maccarrone, B Hambsch, R Landgraf, Cw Turck<br />

Exploring Biomarkers From Pancreatic Cancer Secretome<br />

Xiaohang Zhao (State Key Laboratory of Molecular Oncology, Cancer Institute &<br />

Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, CHINA)<br />

Cardiovascular Proteome Biology<br />

P-WED-102<br />

P-WED-103<br />

P-WED-104<br />

P-WED-105<br />

P-WED-106<br />

P-WED-107<br />

P-WED-108<br />

P-WED-109<br />

P-WED-110<br />

P-WED-111<br />

The Effect Of 7,8-Dihydroxy-3-(3-Methylphenyl) Coumarin On The Protein<br />

Profiles Of Rat Liver<br />

Volkan Altay (Marmara University Faculty of Arts and Sciences, Turkey), Basak<br />

Yuce, Ayse Ogan, Goksel Sener, Mustafa Bulut<br />

Secretome Analysis Of Human Artery Biopsies In The Search For<br />

Atherothrombotic Biomarkers<br />

Gloria Alvarez-Llamas, Fernando de la Cuesta, Veronica M. Darde, Maite Tejerina,<br />

Rocio Juarez, Luis R. Padial, Angel G. Pinto, Maria G. Barderas, Fernando Vivanco<br />

(Department of Immunology. Fundacion Jimenez Diaz / Department of Biochemistry<br />

and Molecular Biology, Universidad Complutense, SPAIN)<br />

New Insights Into The Pathogenesis Of Ectopic Calcification: A Lesson From The<br />

Pxe Model<br />

Giulia Annovi (University of Modena and Reggio Emilia, ITALY), Federica Boraldi, Leon<br />

J Schurgers, Cees Vermeer, Ivonne Pasquali-Ronchetti, Daniela Quaglino<br />

Myocardial Proteomic Profiling Helps Identify Different Forms Of Heart Disease<br />

Gökhan Baykut (Bruker Daltonik GmbH, GERMANY), Matthias Witt, Maria Bergquist,<br />

Hans-Reinhard Zerkowski, Doan Baykut, Jonas Bergquist<br />

Lipolytic Activity Profiling In Mouse Liver<br />

Ruth Birner-Gruenberger (Medical University of Graz, AUSTRIA), Albin Hermetter,<br />

Manfred Kollroser, Heidrun Susani-Etzerodt, Gerald Rechberger<br />

Characterization Of The Murine Cardiac Proteome<br />

Nicolas Bousette (Department of Physiology, University of Toronto, CANADA),<br />

Thomas Kislinger, Ruth Isserlin, Andrew Emili, Anthony Gramolini<br />

Changes In The Rat Aorta Proteome With The Dietary Folate Supply<br />

Patrick Brachet (Institut National de la Recherche Agronomique, FRANCE)<br />

Proteomic Analysis Of A Mouse Model Of Heart Failure Resulting From Cardiac<br />

Hypertrophy<br />

Shaan Chugh (Banting and Best Department of Medical Research, University of<br />

Toronto, CANADA)<br />

Isolation Of Human Arterial Intimal Layer And Single Cells For Proteomic<br />

Analysis<br />

Fernando de la Cuesta (Fundacion Jimenez Diaz-Capio, SPAIN), Gloria Alvarez-<br />

Llamas, Veronica M. Darde, Alicia Donado, Aroa S. Maroto, Luis R. Padial, Angel G.<br />

Pinto, Maria G. Barderas, Fernando Vivanco<br />

Electron Transfer Dissociation (Etd) Enabled Identification Of Specific<br />

Phosphorylation Sites In Key Metabolic Enzymes Of Cardiac Mitochondria<br />

Philip Doran (Ucla, UNITED STATES), Yueju Wang, Ning Deng, Jun Zhang, Chenggong<br />

Zong, Michael Mueller, Paavo Korge, James Weiss, Rolf Apweiler, Peipei Ping<br />

P-WED-112<br />

P-WED-113<br />

P-WED-114<br />

P-WED-115<br />

P-WED-116<br />

P-WED-117<br />

P-WED-118<br />

P-WED-1<strong>19</strong><br />

P-WED-120<br />

P-WED-121<br />

P-WED-122<br />

P-WED-123<br />

Analysis Of Proteins Secreted During Vessel Maturation In An In-Vitro<br />

Angiogenesis Model<br />

Tom Dunkley (Astrazeneca, UNITED KINGDOM), Mark Pearson, Rachel Rowlinson,<br />

Beverley Isherwood, Simon Barry<br />

Proteomic Analysis Of Cardiac Targets Involved In Anesthetic-Induced Preconditioning<br />

Nadine Dyballa (University of Duesseldorf, GERMANY), Christian Schuh, Hendrik<br />

Vogt, Wolfgang Schlack, Nina Weber, Sabine Metzger<br />

Lipid Rafts In Platelets - Novel Signalling Platforms?<br />

Beate Eyrich (Protein Mass Spectrometry and Functional Proteomics Group, Rudolf-<br />

Virchow-Center for Experimental Biomedicine, GERMANY), Albert Sickmann<br />

Characterization Of The Human Platelet Proteome By Shotgun Lc-Ms/Ms Analysis<br />

Marco Gaspari (Dept. Experimental & Clinical Medicine, University of Catanzaro,<br />

ITALY), Shibu Krishnan, Cosimo Gasparri, Giuseppe Argirò, Patrizia Bianchi, Annalisa<br />

Fregola, Daniele Torella, Ciro Indolfi, Giovanni Cuda<br />

Dynamic Cardiac Mitochondrial Proteome Alterations After Ischemia/Reperfusion<br />

Injury<br />

Abdelbary Prince (Department of Physiology and Biophysics, Mitochondrial Signaling<br />

Laboratory, College of Medicine, Cardiovascular and Metabolic Diseases Center, Inje<br />

University, Korea / Department of Biochemistry, Faculty of Veterinary Medicine,<br />

Cairo University, Egypt), Hyungkyu Kim, Samy Abdelaziz, Eman Gouda, Jin Han<br />

Withdrawn<br />

Effects Of Dilated Cardiomyopathy And Immunoadsorption Therapy On Cardiac<br />

Gene Expression<br />

Sabine Ciecholewski (Medical Faculty, University Greifswald, GERMANY), Katrin<br />

Darm, Leif Steil, Alexander Staudt, Elke Hammer, Sacha Aft van Hijum, Heyo K<br />

Kroemer, Reinhardt Kandolf, Stephan B Felix, Uwe Völker<br />

Bh4 Deficiency Impaired Cardiac Mitochondrial Function<br />

Hyoung Kyu Kim (Department of Physiology, Colleage of Medicine, Inje University,<br />

KOREA), Won Sun Park, Abdel Bary Prince, Jin Han<br />

Analysis Of Protein Profiles In Astemizole And Loratadine-Treated Rat<br />

Cardiomyocytes<br />

So Young Kim (Korea Food & Drug Administration, KOREA), Ho-Sang Jeong Ho-Sang<br />

Jeong, Moon Jeong Ko Moon Jeong Ko, Joon Ik Ahn Joon Ik Ahn, Sun Ok Choi, Hye<br />

Joo Chung Hye Joo Chung<br />

Human Plasma Proteome Investigations Into Acute Coronary Microvascular<br />

Disorders<br />

Victoria Kopetz (The Queen Elizabeth Hospital, AUSTRALIA), Megan Penno, Peter<br />

Hoffmann, John Beltrame<br />

iTRAQ Analysis Of Doxorubicin Effect On Rat Heart Myoblast-Derived Cells H9c2<br />

Juraj Lenco (Department of Molecular Pathology, Faculty of Military Health<br />

Sciences, University of Defence, CZECH REPUBLIC), Marek Link, Tomas Simunek,<br />

Martin Sterba, Jiri Stulik<br />

Analysis Of The Platelet Proteome<br />

Urs Lewandrowski (Rudolf-Virchow-Center for Experimental Biomedicine, Protein<br />

Mass Spectrometry and Functional Proteomics Group, University Würzburg,<br />

GERMANY), Rene Zahedi, Katharina Lohrig, Dirk Wolters, Stefanie Wortelkamp,<br />

Thomas Premsler, Albert Sickmann<br />

136 137


P-WED-124<br />

P-WED-125<br />

P-WED-126<br />

P-WED-127<br />

P-WED-128<br />

Participate In The Cardiovascular Gene Ontology Annotation Initiative<br />

Ruth Lovering (Centre for Cardiovascular Genetics, Department of Medicine,<br />

University College London, UNITED KINGDOM), Varsha Khodiyar, Emily Dimmer,<br />

Daniel Barrell, Peter Scambler, Mike Hubank, Rolf Apweiler, Philippa Talmud<br />

Proteomics, Metabolomics And Immunomics On Atherosclerotic Plaques-Derived<br />

Microparticles<br />

Manuel Mayr (Cardiovascular Division, Kings College London, University of London,<br />

UNITED KINGDOM), David Grainger, Ursula Mayr, Aurelie Leroyer, Guy Leseche,<br />

Anissa Sidibe, Xiaoke Yin, Basseti Madhu, Aldrin Gomes, John Griffiths<br />

Phenotyptic Continuum Between Growth And Protection: Analysis Of Organellar<br />

Sub-Proteomes In The Heart<br />

Anna Paulsson (University of California, UNITED STATES), Sarah Warburton, Shuxun<br />

Ren, Sherise Mitchell, Sujing Wang, Yibin Wang, Thomas Vondriska<br />

Proteomics Characterization Of Hemodialysis Membranes Biocompatibility<br />

Luisa Pieroni (Fondazione S. Lucia - Irccs, ITALY), Andrea Urbani, Mario Bonomini,<br />

Santina Lupisella, Barbara Pavone, Sonia Bucci, Vittorio Sirolli, Moreno di Cesare,<br />

Giorgio Federici, Federica Forli<br />

Role Of Endothelial Cells As Targets Of Low-Dose Radiation In Cardiovascular<br />

Diseases<br />

Franka Pluder (Institute of Radiation Biology, Helmholtz Zentrum München – German<br />

Research Center for Environmental Health (GmbH), GERMANY), Reetta Nylund,<br />

Dariusz Leszczynski, Michael Atkinson, Soile Tapio<br />

P-WED-136<br />

P-WED-137<br />

P-WED-138<br />

P-WED-139<br />

P-WED-140<br />

P-WED-141<br />

Investigating Post-Translational Modifications Of Apo B-100 By Oxidative Stress<br />

Katrina Thomson (Glasgow University, UNITED KINGDOM), Edina Silajdzic, Laetitia<br />

Mouls, Corinne Spickett, Andrew Pitt<br />

Mass Spectrometry-Based Analysis Of Nitroxylated Proteins In The Human<br />

Platelet Proteome<br />

Geraldine Walsh (Biomedical Research Centre, CANADA), Michael Hoffman, Dana<br />

Devine, Juergen Kast<br />

Proteomic Analysis Of Failed Thrombolysis Following Acute Myocardial Infarction<br />

Jules Westbrook (Ucd Conway Institute of Biomolecular and Biomedical Research,<br />

University College Dublin, Ireland)<br />

Alterations To The Mitochondrial Subproteome With Myocardial Ischemic<br />

Preconditioning<br />

Melanie Y. White (Johns Hopkins School of Medicine, UNITED STATES), David A.<br />

Brown, Brian O’Rourke, Jennifer E. van Eyk<br />

The Secretome Of Colony Forming Units And Non-Colony Forming Endothelial<br />

Progenitor Cells<br />

Xiaoke Yin (Cardiovascular Division, King’s College London, UNITED KINGDOM),<br />

Ursula Mayr, Colin Evans, Qingzhong Xiao, Qingbo Xu, Manuel Mayr<br />

A Proteomics Study Of Mouse Brain Endothelial Cells After Oxygen And Glucose<br />

Deprivation<br />

Chenggang Zhang (Beijing Institute of Radiation Medicine, CHINA), Yong Gu<br />

P-WED-129<br />

Proteomics Analysis Of Role Of Hsp60 In Digitalis-Induced Toxicity In Endothelial<br />

Cells<br />

Jie Qiu (Shandong University Qilu Hospital, CHINA), Hai-Qing Gao, Xiao-Pei Cui, Gai-<br />

Xia Zhao<br />

P-WED-142<br />

Tec Tyrosine Kinase Signaling In Cardiac Ischemia And Reperfusion<br />

Michael Zhang (Departments of Anesthesiology, Medicine and Physiology, University<br />

of California, UNITED STATES), Sarah Warburton, Sujing Wang, Scherise Mitchell,<br />

Hiroyuki Mano, Thomas Vondriska<br />

P-WED-130<br />

P-WED-131<br />

Label-Free Quantitative Protein Study Of Plasma In Patients With Coronary<br />

Artery Disease<br />

Susanne Ragg (Indiana University School of Medicine, UNITED STATES), Olga Vitek,<br />

Gunther Schadow, Vladimir Fokin, Nadine Lee, Siegmund Braun, Ilka Ott<br />

Human Primary Subcutaneous Adipocytes Are Source Of Many Cytokines And<br />

Chemokines<br />

Marcel de Vries, Marcel van Bruinenberg, Saed Lahham, Desiree Weening, Andrea<br />

Venema, Niels Kloosterhuis, Roel Vonk, Farhad Rezaee (University Medical Centre<br />

Groningen, THE NETHERLANDS)<br />

P-WED-143<br />

Activation Of Aortic Endothelial Cells By Oxidized Phospholipids:<br />

Phosphoproteomic Analysis<br />

Alejandro Zimman (Pathology & Laboratory Medicine, University of California,<br />

UNITED STATES), Sharon S. Chen, Evangelia Komisopoulou, Wan Lam Szeto, Judith<br />

A. Berliner, Thomas G. Graeber<br />

P-WED-132<br />

Mlc Degradation Is Associated With Increased Mmp-2 Activity In Neonatal<br />

Pigs With Hypoxia-Reoxygenation<br />

Jolanta Sawicka, Justyna Fert-Bober, Po-Yin Cheung, Grzegorz Sawicki (University<br />

of Saskatchewan, CANADA)<br />

P-WED-133<br />

Purification Of Endogenous Cardiac Thick Filament Proteins For Ptm<br />

Identification<br />

Sarah B. Scruggs (University of Illinois at Chicago, Center for Cardiovascular<br />

Research, UNITED STATES), Peter M. Buttrick, R John Solaro<br />

P-WED-134<br />

Proteomic Profiling Of The Cardiomyocyte Plasma Membrane<br />

Parveen Sharma (Department of Physiology, University of Toronto, CANADA), Alex<br />

Ignatchenko, Nic Bousette, Andreas Evangelou, Anthony Gramolini, Thomas Kislinger<br />

P-WED-135<br />

Four And A Half Lim Domains Protein 1 (Fhl1) Interactions In Mammalian Muscle<br />

Thiruchelvi Shathasivam (Department of Physiology, University of Toronto, CANADA),<br />

Parveen Sharma, Alex Ignatchenko, Thomas Kislinger, Anthony Gramolini<br />

138 139


Integration And Storage Of Proteomics Data<br />

P-WED-144<br />

P-WED-145<br />

P-WED-146<br />

P-WED-147<br />

Prose – “Software As A Service” For Quantitative Proteomics<br />

Stefan Albaum (Center for Biotechnology, Bielefeld University, GERMANY),<br />

Heiko Neuweger, Sita Lange, Dominik Mertens, Kai Runte, Joern Kalinowski, Tim<br />

Nattkemper, Alexander Goesmann<br />

A Common Sequence Database Format In Proteomics<br />

Pierre-Alain Binz (Swiss Institute of Bioinformatics, Proteome Informatics Group<br />

/ Geneva Bioinformatics (Genebio) Sa, SWITZERLAND), Eugene A. Kapp, Jim<br />

Shofstahl, David Creasy, Uniprot Consortium, Jayson A. Falkner, Philip C. Andrews,<br />

Sean L. Seymour<br />

The Human Muscle Proteome In Unloading-Induced Atrophy: data Management<br />

Using Proteus(Tm)Software.<br />

Gary Coulton (St. George’s, University of London, UNITED KINGDOM), Glen Alder,<br />

Maarten de Boer, Marco Narici, Simon Swindell, Kevin Jones<br />

Proteomics Tools And Pipelines Work Packages 3 & 5 Of Prodac (Proteomics<br />

Data Collection)<br />

Martin Eisenacher (Medizinisches Proteom-Center, Ruhr-Universitaet Bochum,<br />

GERMANY), Phil Jones, Lennart Martens, Fredrik Levander, Michael Kohl, Jari<br />

Häkkinen, Rolf Apweiler, Helmut E. Meyer, Christian Stephan<br />

P-WED-155<br />

P-WED-156<br />

P-WED-157<br />

P-WED-158<br />

P-WED-159<br />

The Psi Semantic Validators – How Compliant Is Your Proteomics Data?<br />

Samuel Kerrien (European Molecular Biology Laboratory (Embl) – European<br />

Bioinformatics Institute, Wellcome Trust Genome Campus, UNITED KINGDOM), Luisa<br />

Montecchi-Palazzi, Florian Reisinger, Bruno Aranda, Andrew R. Jones, Matthias<br />

Oesterheld, Lennart Martens, Henning Hermjakob<br />

Proteincv: Hierarchical Statecharts Data Model For Molecular Information On<br />

Proteins<br />

Per Kraulis (Avatar Software Ab, SWEDEN)<br />

Miape Generator Tool: A Useful Aid To Report Proteomics Experiments According<br />

To Miape Guidelines<br />

Salvador Martínez de Bartolomé (Proteored - National Center for Biotechnolgy-<br />

Csic, SPAIN), Alberto Medina, Jose María Carazo, Juan Pablo Albar<br />

A New Web Standard-Based Interface To Report Proteomics Experiments<br />

J Alberto Medina-Aunon (Proteomics Facility, National Center for Biotechnology<br />

(Cnb-Csic), Spanish Proteomics Institute (Proteored), SPAIN), J Pablo Albar<br />

The International Molecular Exchange Consortium<br />

Sandra Orchard (Embl- European Bioinformatics Institute, UNITED KINGDOM),<br />

Samuel Kerrien, Bruno Aranda, Arnaud Coel, Andrew Chatr-Arymontri, Lukasz<br />

Salwinski, Sylvie Ricard Blum, Rolf Apweiler, Henning Hermjakob<br />

P-WED-148<br />

Prodac Proteomics Data Collection - Coordinated Action Within The 6th Eu<br />

Framework Programme<br />

Christian Stephan (Medizinisches Proteom-Center, Ruhr-Universitaet Bochum,<br />

GERMANY), Tanja Hardt, Martin Eisenacher, Michael Hamacher, Rolf Apweiler,<br />

Jari Häkkinen, Rudi Aebersold, Joel Vandekerckhove, Michael J. Dunn, Frederique<br />

Lisacek, Ron Appel, Simon Hubbard, Pierre-Alain Binz, Martin Blüggel, Herbert<br />

Thiele, John Cottrell, Helmut E. Meyer<br />

P-WED-160<br />

P-WED-161<br />

Using Discovery To Power Targeted Analysis: From Traps To Triples<br />

Amol Prakash (Thermofisher Scientific, UNITED STATES), David Sarracino, Michael<br />

Athanas, Bryan Krastins, Scott Peterman, Kypros Nicholaides, Mary Lopez<br />

Generalized Method For Statistical Analysis Of Peptide Identification Scores<br />

From Ms/Ms Data And Database Searching<br />

Antonio Ramos Fernández (Cnb-Csic, SPAIN)<br />

P-WED-149<br />

Epims: A Versatile Tool For Data Management And Analyses Scheduling<br />

Myriam Ferro (Cea, FRANCE), Véronique Dupierris, Mimi Grebici, Damien Barthe,<br />

Jérôme Garin, Christophe Bruley<br />

P-WED-162<br />

Pass: End-To-End Bioinformatics Data Warehouse For Clinical Proteomics<br />

Gautam Saxena (Integrated Analysis, Inc., UNITED STATES), Julius C-Zar, Cathy<br />

Kimani, Edwin Mulwa<br />

P-WED-150<br />

Accelerating Proteomics Through Integrated Data Management And<br />

Bioinformatics Pipelining<br />

Charles G. Howes, Frank Worsley, Matthew J. Myhre, Mike Sanders, Leonard<br />

J. Foster (Centre for High-Throughput Biology, Department of Biochemistry &<br />

Molecular Biology, University of British Columbia, CANADA)<br />

P-WED-163<br />

Managing Proteomics Data From Generation And Data Warehousing To Central<br />

Data Repository<br />

Herbert Thiele (Bruker Daltonik GmbH, GERMANY), Peter Hufnagel, Jörg Glandorf,<br />

Gerhard Körting, Martin Blüggel, Martin Eisenacher, Helmut E. Meyer, Christian<br />

Stephan<br />

P-WED-151<br />

World-2dpage Repository: Your Contribution To A Large Proteomics Data<br />

Network<br />

Christine Hoogland (Swiss Institute of Bioinformatics, SWITZERLAND), Khaled<br />

Mostaguir, Ron D. Appel, Frederique Lisacek<br />

P-WED-164<br />

Data Processing And Analysis At The Biomolecular Mass Spectrometry And<br />

Proteomics Group<br />

Henk W.P. van den Toorn (Uu, THE NETHERLANDS), Madalina Drugan, Robert<br />

Kerkhoven, Albert Heck, Bas van Breukelen<br />

P-WED-152<br />

P-WED-153<br />

Genome Medicine Database Of Japan Proteomics (Gemdbj Proteomics)<br />

Mutsumi Hosako (Proteome Bioinformatics Project, National Cancer Center<br />

Research Institute, JAPAN), Masayo Yamada, Setsuo Hirohashi, Tadashi Kondo<br />

How Bioinformatics Helps To Achieve And Publish Proteomics Results Following<br />

Publications Guidelines<br />

Deltev Suckau, Peter Hufnagel (Bruker Daltonik GmbH, GERMANY), Ulrike<br />

Schweiger-Hufnagel, Jörg Glandorf, Herbert Thiele, Stefan Weise, Martin Blüggel<br />

P-WED-165<br />

P-WED-166<br />

Integrated Bioinformatics For Biodefense Proteomics<br />

Cathy Wu (Protein Information Resource, UNITED STATES)<br />

Miapegeldb: A Web-Based Submission Tool And Public Repository For Miape Gel<br />

Electrophoresis Documents<br />

Robin Xavier (University of Geneva / Swiss Institute of Bioinformatics,<br />

SWITZERLAND), Christine Hoogland, Ron D. Appel, Frederique Lisacek<br />

P-WED-154<br />

An Integrated Protein Repository For Mining Proteomics Data<br />

Christian Ingrell (Proxeon A/S, DENMARK), Peter Venø, Morten Bern<br />

140 141


Kinase-Protein Substrate Networks<br />

P-WED-167<br />

P-WED-168<br />

P-WED-169<br />

P-WED-170<br />

P-WED-171<br />

Establishing A Kinase Rnai Screen To Investigate Recruitment Of Human<br />

Kinetochore Proteins Mcm21/Cenp-O and Chl4/Cenp-N<br />

Mukta Belwal (Eth Zürich, SWITZERLAND)<br />

Cck Stimulates Peptide Chain Elongation In Mouse Pancreatic Acini And The<br />

Molecular Mechanism<br />

Chaojun Duan (Xiangya Hospital, Central South University, CHINA)<br />

Screen Biomarkers From Human Nasopharyngeal Carcinoma Serum Using A<br />

Proteomics Approach<br />

Chaojun Duan (Xiangya Hospital, Central South University, CHINA)<br />

Nuclear Plcbeta1 Signaling: eef1a2 Is A Novel Phospho-Substrate Of Pkcbeta1<br />

In Myoblast<br />

Manuela Piazzi (Cellular Signalling Laboratory, Department of Anatomical Sciences,<br />

University of Bologna / Cell Biology and Electron Microscopy Laboratory, ITALY),<br />

Alberto Bavelloni, Gabriella Cioffi, Simona D’Aguanno, Andrea Urbani, Nadir Mario<br />

Maraldi, Lucio Cocco<br />

Selective Enrichment And Quantitation Of Phosphoproteins Involved In Cell Proliferation<br />

Michael Major, Rosa Viner, Michael Rosenblatt, Terry Zhang, Vlad Zabrouskov, Sarah<br />

Klipp, Navid Haghdoost (Thermo Scientific, UNITED STATES), Barbara Kaboord, John<br />

Rogers<br />

Proteome Biology Of Infectious Diseases<br />

P-WED-172<br />

P-WED-173<br />

P-WED-174<br />

P-WED-175<br />

P-WED-176<br />

P-WED-177<br />

P-WED-178<br />

P-WED-179<br />

Large Scale Analysis Of Cross Presented Hla Class I Peptides<br />

Michal Bassani-Sternberg, Arie Admon (Technion-Israel Institute of Technology, ISRAEL)<br />

A Proteomic Analysis Of Biofilm Induced By Bile Salts In Vibrio Cholerae O1<br />

Livia Barbosa, Paulo Mascarello Bisch (Unidade Multidisciplinar de Genômica, Rede<br />

Proteoma Do Rio de Janeiro – Ibccf, Ufrj, BRAZIL), Wanda von Krüger<br />

Identification Of The Spi2 Effector Interactome In The Salmonella Cell<br />

Nat Brown (Griffith University, AUSTRALIA), Scott Nankervis, Lindsay Rogers,<br />

Leonard Foster<br />

Proteomes Of Non-Pylori Helicobacter: The Search For Pathogenic Determinants<br />

Winita Fowsantear, Evelyn Argo, Cheryl Ritchie, ElIzabeth Stewart, Emad El-Omar,<br />

Georgina Hold, Phil Cash (University of Aberdeen, UNITED KINGDOM)<br />

New Insights In Dendritic Cells Funtionning Are Revealed By Proteomics<br />

Thierry Rabilloud, Mireille Chevallet (Cea / Irtsv / Lbbsi, FRANCE), Christian Villiers,<br />

Hélène Diemer, Patrice Marche, Alain van Dorssealer<br />

Quorum Sensing Contributes To Proteomic Changes Of Enterohemorrhagic<br />

Escherichia Coli O157:H7<br />

Seung-Hak Cho (Korean National Institute of Health, KOREA), Jong-Chul Kim, Bok<br />

Kwon Lee<br />

Bile Stress Response Of The Enteric Pathogen Vibrio Cholerae<br />

Rukhsana Chowdhury (Indian Institute of Chemical Biology, INDIA), Tanusree Das<br />

Proteomic Analysis Of Nuclear Enriched Fractions From Hcc Liver Tissues<br />

Erika Codarin (Department of Biomedical Sciences and Technologies, University of<br />

Udine, ITALY), Chiara D’Ambrosio, Andrea Scaloni, Laura Cesaratto, Carlo Vascotto,<br />

Umberto Baccarani, Claudio Avellini, Claudio Tiribelli, Franco Quadrifoglio, Gianluca Tell<br />

P-WED-180<br />

P-WED-181<br />

P-WED-182<br />

P-WED-183<br />

P-WED-184<br />

P-WED-185<br />

P-WED-186<br />

P-WED-187<br />

P-WED-188<br />

P-WED-189<br />

P-WED-<strong>19</strong>0<br />

P-WED-<strong>19</strong>1<br />

Identification Of Herpes Simplex Virus Type 1 Signaling Targets In Human<br />

Hepatoma Cells By Functional Organelle Proteomics<br />

Fernando Corrales (Foundation for Applied Medical Research (Fima), SPAIN), Enrique<br />

Santamaría, Corinne Potel, Joaquín Fernández-Irigoyen, Rubén Hernández-Alcoceba,<br />

Alberto Epstein<br />

Validating Divergent Orf Annotation In M. Tuberculosis Datasets Using A Ltq-<br />

Orbitrap<br />

Gustavo de Souza (Gades Institute, Dept. of Immunology and Microbiology, Uib,<br />

NORWAY), Hiwa Malen, Tina Softland, GisLe Saelesminde, Inge Jonassen, Harald<br />

Wiker<br />

Adaptation Of E.Coli Protein Expression In The Mouse Gastrointestinal Tract<br />

Wolfram Engst (German Institute of Human Nutrition Potsdam-Rehbrücke,<br />

GERMANY), Carl Alpert, Jacqueline Scheel, Gunnar Loh, Michael Blaut<br />

Withdrawn<br />

Proteomic Analysis Of Mycoplasma Penetrans Membrane<br />

Mario Ferrer-Navarro (Institut de Biotecnologia I Biomedicina, SPAIN), Raquel<br />

Planell, Sílvia Bronsoms, Núria Colomé, Francesc Canals, Francesc Xavier Aviles,<br />

Enrique Querol<br />

Proteomic Study Of Tyk2 Deficient Murine Macrophages In Response To Poly I:c<br />

Tom Grunert (Institute of Chemical Technologies and Analytics, Vienna University<br />

of Technology / Institute of Animal Breeding and Genetics, University of Veterinary<br />

Medicine, AUSTRIA), Birgit Strobl, Martina Marchetti, Ingrid Miller, Marta Radwan,<br />

Claus Vogl, Manfred Gemeiner, Günter Allmaier, Mathias Müller<br />

The Secreted Proteome Of Epidemic Cystic Fibrosis (Cf) Pseudomonas<br />

Aeruginosa Aes-1<br />

Nathan Hare (School of Molecular and Microbial Biosciences, University of Sydney,<br />

AUSTRALIA), Colin Harbour, Barbara Rose, Stuart Cordwell<br />

Altered Proteome In Human Endothelial Cells During Dengue Virus Infection<br />

Rattiyaporn Kanlaya (Department of Immunology and Immunology Graduate Program,<br />

Faculty of Medicine Siriraj Hospital, Mahidol University / Medical Molecular Biology<br />

Unit, Office for Research and Development, Faculty of Medicine Siriraj Hospital,<br />

Mahidol University, THAILAND), Sa-Nga Pattanakitsakul, Supachok Sinchaikul, Shui-<br />

Tein Chen, Visith Thongboonkerd<br />

Hcv Induced Cirrhosis: A Proteomic Approach<br />

Rizma Khan (University of Karachi, Pakistan), Saadia Zahid, Nikhat Ahmed, M Ataur<br />

Rahman<br />

Identification Of Immunogenic Proteins From Chlamydophila Pneumoniae Knih-1<br />

Kwang-Jun Lee (National Institute of Health, Kcdc, KOREA), Sung-Ha Park, Su-Jin<br />

Kwon, Young-Chang Kim, Yeon-Ho Kang<br />

Detection Of Phosphorylcholine-Modified Peptides By Precursor Ion Scanning<br />

And Mrm<br />

Christof Lenz, Julia Grabitzki, Günter Lochnit, Donna Potts (Applied Biosystems,<br />

GERMANY)<br />

Dissecting Phosphorylcholine-Modified Proteins In The Parasite Plasmodium<br />

Falciparum<br />

Julia Grabitzki, Sascha Koncarevic, Katja Becker, Guenter Lochnit (Institute of<br />

Biochemistry, University Giessen, GERMANY)<br />

142 143


P-WED-<strong>19</strong>2<br />

P-WED-<strong>19</strong>3<br />

P-WED-<strong>19</strong>4<br />

Proteomic Profile Of The Upper Airways Of Children Suffering Viral Infection<br />

Luis M. Teran (Instituto Nacional Enfermedades Respiratorias, Mexico), Sabrina<br />

Rüggeberg, Jose Luis Hernandez, Thomas Franz<br />

Proteomic Analysis Of Cytoplasmic And Surface Proteins From Yeast Cells,<br />

Hyphae, And Biofilms Of Candida Albicans<br />

Martínez-Gomariz Montse (Unidad de Proteómica, Pcm-Ucm, SPAIN), Perumal<br />

Palani, Mekala Satish, Nombela César, Chaffin W. Lajean, Gil Concha<br />

Direct Identification Of Uropathogens In Urine Samples With Maldi-TOF-Ms<br />

Frank Mosel (Institute of Hygiene and Occupational Medicine, GERMANY)<br />

P-WED-206<br />

P-WED-207<br />

P-WED-208<br />

Proteomic Analysis Of The Antibiotic Response Of Stenotrophomonas Maltophilia<br />

Laurence van Oudenhove (L-Probe, Ugent, BELGIUM)<br />

Dynamics Of The Proteomes Of Mammalian Cell Lines During Influenza A Virus<br />

Infection<br />

Diana Vester (Bioprocess Engineering, Otto-Von-Guericke University Magdeburg,<br />

GERMANY), Erdmann Rapp, Yvonne Genzel, Doerte Gade, Udo Reichl<br />

Quantitative Proteomics Analysis Of Human Macrophage Activation<br />

Sara Vosmaer (University Medical Centre Groningen / Centre for Medical Biomics,<br />

THE NETHERLANDS), Marcel de Vries, Roel Vonk, Han Roelofsen<br />

P-WED-<strong>19</strong>5<br />

P-WED-<strong>19</strong>6<br />

P-WED-<strong>19</strong>7<br />

P-WED-<strong>19</strong>8<br />

P-wed-<strong>19</strong>9<br />

P-WED-200<br />

P-WED-201<br />

P-WED-202<br />

P-WED-203<br />

P-WED-204<br />

P-WED-205<br />

Protein Expression Patterns In Adult Angiostrongylus Costaricensis Nematode<br />

Ana Neves-Ferreira (Laboratório de Toxinologia, Instituto Oswaldo Cruz, BRAZIL), Juliana<br />

São Luis, Ester Mota, Ileana León, Richard Valente, Henrique Lenzi, Jonas Perales<br />

Proteomics To Characterise Activation Of Innate Immunity In Human Keratinocytes<br />

Tuula Nyman (Institute of Biotechnology, FINLAND), Tiina Öhman, Niina LIetzén,<br />

Rauna Tanskanen, Sampsa Matikainen<br />

Proteome Characterization Of Influenza A Virus Infected Human Primary<br />

Macrophages<br />

Tiina Öhman (Institute of Biotechnology, University of Helsinki, FINLAND), Johanna<br />

Rintahaka, Sampsa Matikainen, Tuula Nyman<br />

Plasmodium Knowlesi And Rheses Red Blood Cell Proteomics<br />

Erica Pasini (Biomedical Primate Research Centre, THE NETHERLANDS), Matthias<br />

Mann, Alan Thomas<br />

Proteomic Analysis Of Host Responses In Human Foreskin Fibroblast Cells During<br />

Dengue Virus Infection<br />

Sa-Nga Pattanakitsakul (Medical Molecular Biology Unit, Office for Research and<br />

Development, Faculty of Medicine Siriraj Hospital, Mahidol University, THAILAND),<br />

Kamonthip Rungrojcharoenkit, Rattiyaporn Kanlaya, Supachok Sinchaikul, Shui-Tein<br />

Chen, Visith Thongboonkerd<br />

Withdrawn<br />

Proteomics And Its Role In The Clinical Diagnosis Diseasea<br />

Maryam Saleh (Pasteur Institute of Iran, Iran)<br />

Fungal Pathogen Pseudallescheria Boydii Secreted Proteins Characterization<br />

Jan Sklenar (Institute of Microbiology, CZECH REPUBLIC), Bara Fliedrova, Vladimir<br />

Havlicek<br />

From Target Identification To Drug Discovery: The Hiv-1 / Human Ledgf - Case Study<br />

Petra Tafelmeyer (Hybrigenics Sa Services, FRANCE), Philippe Guedat, Jean-<br />

Christophe Rain, Etienne Formstecher, Fanny Moisant, Anne Pecquery-Texier,<br />

Richard Benarous, Sabine Barbey, Jean-Marc Paris, Stephane Emiliani<br />

Effectors Molecules Secreted By The Obligate Intercelluar Pathogen Coxiella<br />

Burnetti<br />

Georgios Tsiotis (University of Crete, Dept. Of Chemistry, Greece), Georgios Samoilis,<br />

Michalis Aivaliotis, Iosif Vranakis, Anastasia Papadioti, Anna Pasroulaki, Yannis Tselentis<br />

Optimized Alkaline Proteome Mapping Of The Human Parasite Trypanosoma Cruzi<br />

Marcelo Valle de Sousa (University of Brasilia, BRAZIL), Adriana Magalhães, Sebastien<br />

Charneau, Jaime Paba, Rafael Guercio, Jaime Santana, Antonio Teixeira, Carlos<br />

André Ricart<br />

Proteomics and Epigenetics<br />

P-WED-209<br />

P-WED-210<br />

P-WED-211<br />

P-WED-212<br />

P-WED-213<br />

P-WED-214<br />

P-WED-215<br />

P-WED-216<br />

P-WED-217<br />

On The Protein Profile Of Pxe Fibroblasts: From Genetic To Epigenetic<br />

Pathogenesis<br />

Federica Boraldi (University of Modena and Reggio Emilia, ITALY), Giulia Annovi,<br />

Deanna Guerra, Roberta Tiozzo, Ivonne Pasquali-Ronchetti, Daniela Quaglino<br />

Differential Proteomics For Priamry And Secondary Polyposis And Cftr Network.<br />

Ludovic Jeanson, Chiara Guerrera, André Coste, Estelle Escudier, Serge Amselem,<br />

Aleksander Edelman (Inserm / Université Paris Descartes / Plateau Proteome<br />

Necker, FRANCE)<br />

Searching For Proteins Involved In Lymphoma: A Network Of Proteomic And<br />

Transcriptomic Clues<br />

Anouk Emadali (Cea, Dsv, Irtsv, Laboratoire D’Etude de la Dynamique Des<br />

Protéomes, FRANCE), Sylvie Kieffer, Christophe Masselon, Mary Callanan, Sophie<br />

Rousseaux, Saadi Khochbin, Jérôme Garin, Myriam Ferro<br />

Proteomic Analysis Of Protein Complement During Honeybee (Apis Mellifera)<br />

Drone Egg Development<br />

Jianke Li (Institute of Apicultural Research, Chinese Academy of Agircultural<br />

Science, CHINA)<br />

Proteomic Analysis To Evaluate The Effects On Colon Cancer Cells Of A Novel<br />

Hdac Inhibitor<br />

Alberto Milli (Universitã Degli Studi di Verona, Dip. Scientifico E Tecnologico,<br />

Laboratorio di Proteomica, ITALY), Daniela Cecconi, Lello Zolla, Franco Zunino,<br />

Federico Odreman, Pier Giorgio Righetti<br />

Human Corneal Epithelial Cell Migration: An Epigenetic Approach<br />

Syed Zulfiqar Ali Naqvi (Neurochemistry Research Unit, Department of<br />

Biochemistry, University of Karachi / Research Laboratory, Department of Biological<br />

& Biomedical Sciences, Aga Khan University, Pakistan), Shamim Mushtaq, Anwar<br />

Ali Siddiqui, Nikhat Ahmed<br />

A Mass Spectrometric Analysis Of Embryonic Zebrafish Proteins<br />

Angel Pizarro (University of Pennsylvania, UNITED STATES), Margaret Lucitt, Tom<br />

Price, Tilo Grosser, Weichen Wu, Anastasia Yocum, Christoph Seiler, Michael Pack,<br />

Ian Blair Blair, Garret Fitzgerald<br />

Proteomic Analysis Of Models Of Ovarian Cancer Tumour Suppression<br />

John Sinclair (Ucl, UNITED KINGDOM)<br />

Efficient Procedures For Avoiding Human Keratin Contaminations During 2d Gel<br />

Proteomics Analysis<br />

Bo Xu (Niigata University, JAPAN), Zongjiang Zhao, Ying Zhang, Yutaka Yoshida,<br />

Eishin Yaoita, Tadashi Yamamoto<br />

144 145


Proteomics Of The Nervous Systems<br />

P-WED-218<br />

P-WED-2<strong>19</strong><br />

P-WED-220<br />

P-WED-221<br />

Enhanced Peptide Extraction In Combination With Targeted Ms For Improved<br />

Identification Of The Nervous Tissue Peptidome<br />

Maarten Altelaar (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />

University, THE NETHERLANDS), Shabaz Mohammed, Roger Adan, Albert Heck<br />

Withdrawn<br />

Neuropeptidomic And Imaging Ms Strategies For Studying Experimental<br />

Parkinson’s Disease<br />

Per Andren (Uppsala University, SWEDEN), Maria Falth, Anna Nilsson, Karl Skold,<br />

Marcus Svensson, Mats Boren, Malin Andersson, David Fenyo, Per Svenningsson<br />

Seldi-Tof Ms and MALDI-TOF-Tof Ms Detection Of Proteomic Biomarkers For<br />

Glaucoma In Neuroretinal Cells<br />

Katharina Bell (Experimental Ophthalmology, Dept. of Ophthalmology, University of<br />

Mainz, GERMANY), G Seigel, N Pfeiffer, FH Grus<br />

P-WED-229<br />

P-WED-230<br />

P-WED-231<br />

P-WED-232<br />

Protein Expression Changes Involved In Early Mitochondrial Dysfunction In<br />

Senescence-Accelerated Mouse Revealed By Comparative Proteomic Analysis<br />

Jianguo Ji (Department of Biochemistry and Molecular Biology, College of Life<br />

Sciences, National Laboratory of Protein Engineering and Plant Genetic Engineering,<br />

Peking University, CHINA)<br />

Quantitative Proteomics Analysis Of Specific Carbonylated Proteins In The<br />

Temporal Lobe Of Aged Rat: The Deterioration Of Antioxidant System<br />

Shaoyi Ji (The National Laboratory of Protein Engineering and Plant Genetic<br />

Engineering, College of Life Sciences, Peking University, CHINA)<br />

Comprehensive Analysis Of Human And Chimpanzee Brain Proteomes<br />

Philipp Khaitovich (Cas-Mpg Institute for Computational Biology, CHINA), Xing Fu,<br />

Ning Fu, Wei Chen, Svante Paabo, Rong Zeng<br />

Interindividual Differences In Protein Identities And Abundances In Cerebrospinal<br />

Fluid Of Controls<br />

Robert-Jan Lamers (Erasmus Mc, THE NETHERLANDS)<br />

P-WED-222<br />

P-WED-223<br />

P-WED-224<br />

P-WED-225<br />

Identification Of Novel Abeta/App Isoforms In Human Cerebrospinal Fluid And<br />

Plasma<br />

Ann Westman-Brinkmalm (Clinical Neurochemistry Laboratory, Sahlgrnska University<br />

Hospital, SWEDEN), Erik Portelius, Gunnar Brinkmalm, Henrik Zetterberg, Kaj<br />

Blennow<br />

Reliable Biostatistical Analysis Of Differentially Expressed Spots From 2-De Gels<br />

Oliver Broedel (A+M Proteome Science Berlin, GERMANY), Ulrich Mansmann, Murat<br />

Eravci, Stephanie Weist, Andreas Baumgartner<br />

Pi Injuring Effect On A Dopaminergic Nb Cell Line Model And Estradiol Rescue<br />

Annamaria D’Alessandro (Santa Lucia Foundation-Irccs, Section of Proteomics and<br />

Metabonomics / University of Rome “Tor Vergata”, ITALY), Simona D’Aguanno, Maria<br />

Teresa Cencioni, Adamo Diamantini, Luca Battistini, Luisa Pieroni, Sergio Bernardini,<br />

Giorgio Federici, Andrea Urbani<br />

Quantitative Analysis Of Differentially Expressed Brain Proteins In The Eae-<br />

Model For Multiple Sclerosis<br />

Ruth Daniels (Hasselt University, Biomedical Research Institute (Biomed) and<br />

Transnationale Universiteit Limburg, School of Life Sciences, BELGIUM), Annelies<br />

Vanheel, Kurt Baeten, Jerome Hendrix, Johan Robben, Jean-Paul Noben, Piet<br />

Stinissen<br />

P-WED-233<br />

P-WED-234<br />

P-WED-235<br />

P-WED-236<br />

P-WED-237<br />

Longitudinal Analysis Of Csf In The Assessment Of Alzheimer’s Disease Ivig<br />

Immunotherapy<br />

Kelvin Lee (University of Delaware, UNITED STATES), Leila Choe, Norman Relkin<br />

Comparative Proteome Analysis Of Rat Spinal Cord Protein Expression After<br />

Severe Traumatic Injury<br />

Cui Li (Department of Neurosurgery, Xiangya Hospital, Central South University,<br />

CHINA), Xuejun Li, Lan Gu<br />

Protein Profiling Of Guillain-Barre’ Patients Cerebrospinal Fluid By 2de And Ms<br />

Santina Lupisella (Centro Europeo Ricerca Sul Cervello, Irccs-Fondazione Santa<br />

Lucia / Dipartimento di Medicina di Laboratorio, Policlinico di Tor Vergata, ITALY),<br />

Simona D’Aguanno, Gian Vico Melzi D’Eril, Alessandra Barassi, Diego Franciotta,<br />

Alessandra Lugaresi, Sergio Bernardini, Andrea Urbani, Giorgio Federici<br />

Gfap Is Lipoxidated In Frontotemporal Lobar Degeneration<br />

Anna Martinez (Universitat de Barcelona, SPAIN), Anna Gómez, Isidre Ferrer<br />

Amyloid Precursor Protein Intracellular Domain (Aicd) - Dependent Modulation<br />

Of Protein Abundance<br />

Thorsten Müller (Medizinisches Proteom Center, Funktionelle Proteomik, Ruhr-<br />

University Bochum, GERMANY), Anna Ulrich, Katrin Marcus<br />

P-WED-226<br />

P-WED-227<br />

Quantitative Analysis Of 5 Subcellular Fractions From Rat Brain By 2-D Gel<br />

Electrophoresis<br />

Murat Eravci (Department of Radiology and Nuclear Medicine (Radiochemistry),<br />

Charité Universitätsmedizin / A+M Proteome Science, GERMANY), Oliver Broedel,<br />

Stephanie Weist, Selda Eravci, Andreas Baumgartner<br />

Oxidation Of Glycolitic Enzymes In Frontal Cortex Occurs In Aging And Is<br />

Increased In Dlb<br />

Anna Gomez (Universitat de Barcelona, SPAIN)<br />

P-WED-238<br />

P-WED-239<br />

Altered Protein Expression In The Brain Of Alzheimer’s Disease Mouse Model,<br />

Appswe/Ps1de9<br />

Choongseob Oh (Gwangju Institute of Science & Technology (Gist), KOREA),<br />

Hyunwoo Choi, Eun Sil Park, Jong Hyuk Yoon, Zee-Yong Park, Yung Joon Yoo<br />

Proteomic Profiling Of Human Ventricular Cerebrospinal Fluid<br />

Peter Pingerelli, Haroon Saleem, Victor Ozols, Becky Duffy, Charles Adler, Thomas<br />

Beach, Holly Shill, Marwan Sabbagh, John Caviness, Richard Burns (Barrow<br />

Neurological Institute, UNITED STATES)<br />

P-WED-228<br />

Immune Response Biomarker Profiling In Glaucoma Patients By Means Of Protein<br />

Micro-Arrays (Protoarray)<br />

Franz Grus (Experimental Ophthalmology, Dept. of Ophthalmology, University of<br />

Mainz, GERMANY), D Buhr, Lissa Freeman-Cook, Nils Boehm, Norbert Pfeiffer<br />

P-WED-240<br />

P-WED-241<br />

Proteomic Approach To Determination Of Relative Expression Of Vdac Isoforms<br />

Mirele Daiana Poleti (Universidade de São Paulo, BRAZIL), Carla Rossini Crepaldi, Andrea<br />

Cristina Tesch, Flávia Simone Munin, Marcelo Cerqueira César, Marcos Nogueira Eberlin<br />

Neuropeptidomic Analysis In Embryonic Quail Diencephalon<br />

Birger Scholz (Department of Pharmaceutical Biosciences, Centre for Reproductive<br />

Biology, Uppsala University, SWEDEN), Henrik Alm, Anna Mattsson, Anna Nilsson,<br />

Mikhail Savitski, Maria Fälth, Kim Kultima, Karl Sköld, Per E Andren, Lennart Dencker<br />

146 147


P-WED-242<br />

P-WED-243<br />

P-WED-244<br />

P-WED-245<br />

P-WED-246<br />

P-WED-247<br />

P-WED-248<br />

P-wed-249<br />

P-WED-250<br />

P-WED-251<br />

Test Of Protein Extraction Systems For Downstream Protein Profiling Studies<br />

With Magnetic Beads<br />

Susanne Schwonbeck (Cea / Institut de Genomique, Centre National de Genotypage,<br />

FRANCE), Duong Nguyen Thi Thuy, Ivo G. Gut<br />

Profiling Of Csf By MALDI-Tof Mass Spectrometry: Assessment Of Magnetic<br />

Bead Based Enrichment<br />

Somdutta Sen (The Centre for Genomic Application, INDIA), Reena Arora, Sagarika<br />

Haldar, Jaya Sivaswami Tyagi, Neera Sharma, Vijay Kumar Gupta, Krishnamoorthy<br />

Narayanasamy<br />

Exploring The Cerebral Hypoxome<br />

Roos van Elzen (University of Antwerp, BELGIUM), Bart Ghesquière, Evy Timmerman,<br />

Kris Geveart, Sylvia Dewilde, Luc Moens<br />

Explorative Proteomics And Metabolomics Of Human Csf Following Pk-Pd<br />

Analyses<br />

Alain van Gool (Organon, A Part of Schering-Plough Corporation, THE NETHERLANDS),<br />

Benno Ingelse, Maarten Sollewijn Gelpke, Huub-Jan Kleijn, Sushmita Mimi Roy, Chris<br />

Becker, Felice de Jong, Danny Alexander, Jacques Schipper<br />

Lc-MALDI Profiling Analysis Of Csf<br />

Judith Barends (Organon, A Part of Schering-Plough Corporation, THE NETHERLANDS),<br />

Maarten Sollewijn Gelpke, Alain van Gool, Eckhard Belau, Detlev Suckau, Sven Brand<br />

Cognitive Performance And Age-Related Changes In The Hippocampal Proteome<br />

Willard Freeman, Heather Vanguilder (Penn State College of Medicine, UNITED<br />

STATES), Willard Freeman<br />

Effects Of Ifn-Beta On Astrocytes: A Proteomic And Nanotechnological<br />

Approach<br />

Daniele Vergara (National Nanotechnology Laboratory of Infm-Cnr, Isufi,<br />

University of Salento, ITALY), Roberta Martignago, Stefano Leporatti, Francesco de<br />

Nuccio, Giuseppe Nicolardi, Rosaria Rinaldi, Michele Maffia<br />

Proteomic Analysis Of Hippocampal Remapping<br />

Evelyn Wang (Exelixis, Inc., UNITED STATES)<br />

Effects Of Different Post Mortem Conditions On The Proteome Of 11 Rat Brain<br />

Areas<br />

Stephanie Weist (A+M Proteome Science, GERMANY), Murat Eravci, Oliver Broedel,<br />

Selda Eravci<br />

Toward A Better Understanding Of Human Brain Proteome: Membrane Proteome<br />

Analysis Of Brain Regions Using 2de<br />

Saadia Zahid (Neurochemistry Research Unit, Department of Biochemistry,<br />

University of Karachi, Pakistan), Rizma Khan, Afshan Wasti, AR Asif, Ahsana Dar,<br />

Nikhat Ahmed<br />

Quantification Ii<br />

P-WED-252<br />

P-WED-253<br />

P-WED-254<br />

P-WED-255<br />

P-WED-256<br />

P-WED-257<br />

P-WED-258<br />

P-WED-259<br />

P-WED-260<br />

P-WED-261<br />

P-WED-262<br />

Evaluation Of Label-Free Proteomics For Comprehensive Proteome Studies<br />

Sebastian Link (Medizinisches Proteom-Center, Ruhr-University Bochum,<br />

GERMANY), Barbara Sitek, Birgit Korte, Christian Stephan, Wolfgang Jabs, Carsten<br />

Baessmann, Martin Blueggel, Daniel Chamrad, Helmut E. Meyer, Kai Stuehler<br />

Rapid Sample Processing For Quantitative Proteomics Using High Intensity<br />

Focused Ultrasounds<br />

Daniel Lopez-Ferrer (Pacific Northwest National Laboratory, UNITED STATES), Tyler<br />

Heibeck, Konstantinos Petritis, Kim Hixson, Weijun Qian, Matthew Monroe, Anoop<br />

Mayampurath, Mikhail Belov, David Camp, Richard Smith<br />

Quantification Of Glyoxalase I, A Biomarker For A Mouse Model Of Trait Anxiety<br />

Giuseppina Maccarrone (Max Planck Institute of Psychiatry, GERMANY), Susanne<br />

Ciniawsky, Boris Hambsch, Christiane Rewerts, BirgiT Bisle, Christoph Turck<br />

Quantification Of Insulin And Other Biosimilars At Microdosing Levels Using Lc-Ms/Ms<br />

Louis Maljers (Thermo Fisher Scientific, UNITED STATES), Jonathan Mcnally, Rohan Thakur<br />

Global Sumo2 Proteome Dynamics In Response To Heat Shock<br />

Ivan Matic (Department of Proteomics and Signal Transduction, Max Planck Institute<br />

for Bioch, GERMANY), Filip Golebiowski, Jürgen Cox, Matthias Mann, Ronald Hay<br />

Targeted Mass Spectrometry Of sirna Based Rna Interference On Gapdh At<br />

The Protein Level<br />

Sahana Mollah (Applied Biosystems, UNITED STATES)<br />

Culture-Derived Isotope Tag (Cdit) Is Powerful Technique For The Quantitative<br />

Proteomics<br />

Tatsuji Nakamura (Eisai Co., Ltd. Laboratory of Core Technology, JAPAN), Yoshiya<br />

Oda, Junro Kuromitsu<br />

Immunogenicity Testing In The Presence Of Excess Protein Therapeutic Using<br />

Immunoprecipitation And Quantitative Mass Spectrometry<br />

Hendrik Neubert (Pfizer Inc, UNITED KINGDOM), Chris Grace, Klaus Rumpel, Ian James<br />

Vems: A Software For Quantitation And Analysis Of 18o Labelled Peptides<br />

Miren Josu Omaetxebarria (University of The Basque Country, Biochemistry and<br />

Molecular Biology Department, SPAIN), Kerman Aloria, Jesus Maria Arizmendi, Rune<br />

Matthiesen<br />

Intelligent Use Of Retention Time For Higher Order Multiple Reaction Monitoring<br />

Multiplexing- Scheduled Mrm Algorithm<br />

Madalina Oppermann (Applied Biosystems, SWEDEN), Christie Hunter<br />

Endoplasmic Reticulum Stress In Insulin Producing Ins-1e Cells: A 2d-Dige Analysis<br />

Lut Overbergh (Legendo, Catholic University Leuven, BELGIUM), Wannes D’Hertog,<br />

Kasper Lage, Daen Hansen, Etienne Waelkens, Decio Eizirik, Chantal Mathieu<br />

P-WED-263<br />

P-WED-264<br />

Automating High-Throughput Srm Assays Without Sacrificing Sensitivity<br />

Scott Peterman (Thermo Fisher Scientific, UNITED STATES), Amol Prakash, Mary<br />

Lopez, David Sarracino, Bryan Krastins, Claire Dauly<br />

Quantitative Proteome Analysis Of Human Neuronal Cells Treated By Clostridium<br />

Botulinum C3exoenzyme<br />

Marika Victoria Muetzelburg, Fred Hofmann, Ingo Just, Andreas Pich (Hannover<br />

Medical School, Department of Toxicology, GERMANY)<br />

148 149


P-WED-265<br />

iTRAQ-Analysis Of A Cell Culture Model For Malignant Transformation<br />

Stephanie Pütz (Rudolf Virchow Center, Dfg Research Center for Experimental Biomedicine,<br />

University of Wurzburg, GERMANY), Andreas Böhm, Thorsten Stiewe, Albert Sickmann<br />

P-WED-278<br />

Lc-Ms Based Quantitation Of Proteins Separated By Gel-Electrophoresis<br />

Zoltan Szabo (Department of Medical Chemistry, University of Szeged, HUNGARY),<br />

Istvan Foldi, Judit Szeline Szomor, Tamas Janaky<br />

P-WED-266<br />

P-WED-267<br />

P-WED-268<br />

Comparative Analysis Of Urine Proteins By 2d-Hplc Via Fluorescence Detection<br />

Xiaoqiang Qiao (National Chromatographic R. &. A. Center, Dalian Institute of<br />

Chemical Physics, CHINA), Junfeng Ma, Lihua Zhang, Zhen Liang, Yukui Zhang<br />

Acute Proteomic Response Of Muscle To Prednisone And Testosterone<br />

Erica Reeves (Children’s National Medical Center, UNITED STATES)<br />

Application Of Qconcat Technology To Protein Quantification<br />

Jennifer Rivers (University of Liverpool, UNITED KINGDOM), Deborah Simpson,<br />

Simon Gaskell, Robert Beynon<br />

P-WED-279<br />

P-WED-280<br />

P-WED-281<br />

Cysteinyl Peptide Enrichment Combined With iTRAQ As An Alternative To Icat<br />

Vojtech Tambor (Institute of Molecular Pathology, CZECH REPUBLIC)<br />

Protein Quantitation Using Multiple Reaction Monitoring<br />

Ning Tang (Agilent Technologies, UNITED STATES), Christine Miller<br />

Protein Quantification Using Laser Induced Fluorescence Detector And Nanoesi-<br />

Ecd-Ms/Ms<br />

Caroline Tokarski, Claude Netter, Jocelyne Tahar, Christian Rolando (Université Des<br />

Sciences et Technologies de Lille, FRANCE)<br />

P-WED-269<br />

P-WED-270<br />

P-WED-271<br />

P-WED-272<br />

P-WED-273<br />

P-WED-274<br />

P-WED-275<br />

P-WED-276<br />

P-WED-277<br />

Vems: A Tool To Quantify iTRAQ Labeled Samples<br />

Eva María Rodríguez Suárez (Cicbiogune, SPAIN), Felix Elortza, Jose María Mato,<br />

Rune Matthiesen<br />

Cilair: A Novel, Quantitative Method To Study Tissue Secretome Changes<br />

Han Roelofsen (University Medical Centre Groningen, Centre for Medical Biomics,<br />

THE NETHERLANDS), Desiree Weening, Marcel de Vries, Annemieke Hoek, Roel J. Vonk<br />

Targeted Analysis Of The Proteome And Phosphoproteome Of The Human Hepatocyte<br />

Anke Schnabel (Medizinisches Proteom-Center, Ruhr-Universitaet Bochum,<br />

GERMANY), Elmar Langenfeld, Gorden Redlich, Bettina Serschnitzki, Nicolai Bache,<br />

Andreas Nussler, Ole Jensen, Ulrich Zanger, Helmut Meyer, Katrin Marcus<br />

Integrated Workflow For Biomarker Discovery, Assay Development And<br />

Validation Using Tandem Mass Tags<br />

Peter Schulz-Knappe (Proteome Sciences Plc, Uk / Proteome Sciences R&D GmbH<br />

& Co Kg, GERMANY), Karsten Kuhn, Darragh O´Brien, Malcolm Ward, Helen Byers<br />

Identification Of Microrna Targets By Pulsed Silac<br />

Bjoern Schwanhaeusser, Nadine Thierfelder, Zhou Fang, Manfred Gossen, Nikolaus<br />

Rajewsky, Matthias Selbach (Max Delbrueck Center for Molecular Medicine,<br />

GERMANY)<br />

Up-Regulation Of Glycolytic Enzymes In Proteins Secreted From Human Colon<br />

Cancer Cells With 5-Fluorouracil Resistance<br />

Young-Kyoung Shin (Cancer Research Institute and Cancer Research Center, Seoul<br />

National University / Research Institute and Hospital, National Cancer Center,<br />

KOREA), Byong Chul Yoo, Kyung Hae Jung, Jae-Gahb Park<br />

Proteome Analysis Of Lung Carcinoma Cell Line A549 Using Label-Free And Dige<br />

Techniques<br />

Barbara Sitek (Ruhr-Universitaet-Bochum, GERMANY), Sebastian Link, Birgit Korte,<br />

Christian Stephan, Wolfgang Jabs, Carsten Baesmann, Martin Blüggel, Daniel C.<br />

Chamrad, Helmut E. Meyer, Kai Stühler<br />

2d Liquid Fractionation Of Proteins For Quantitative Mass Spectrometry In<br />

Cancer Research<br />

Helena Skalnikova (Institute of Animal Physiology and Genetics As Cr, V.V.I., CZECH<br />

REPUBLIC), Jirina Martinkova, Petr Halada, Andreas Ekefjard, Daniel Enetoft,<br />

Michaela Zilvarova, PeTr Dzubak, Hana Kovarova<br />

Absolute Quantification Of Plasma And Serum Proteins: Gaucher Disease<br />

Diagnostic Markers<br />

Richard Sprenger (Academic Medical Center, THE NETHERLANDS), Craig Dorschel,<br />

Hans Vissers, Hans Aerts<br />

P-WED-282<br />

P-WED-283<br />

P-WED-284<br />

P-WED-285<br />

P-WED-286<br />

P-WED-287<br />

P-WED-288<br />

P-WED-289<br />

P-WED-290<br />

P-WED-291<br />

Top-Down Vs Bottom-Up Stable Isotope Based Proteomics For Protein Quantification<br />

Yury Tsybin (Biomolecular Mass Spectrometry Laboratory, Ecole Polytechnique<br />

Fédérale, SWITZERLAND), Thibaut Douche, Hisham Ben Hamidane, Michael Affolter,<br />

Martin Kussmann, Adrien Schmid<br />

Pitfalls In Silac Analysis. Illustration By The Identification Of Syk Kinase Substrates<br />

Romain Larive, Serge Urbach (Igf / Plateforme Protéomique, FRANCE), Kévin<br />

Contrepois, Joël Poncet, Patrick Jouin, Guilhem Mascré, Alain Sahuquet, Peter<br />

Coopman, Nadir Bettache<br />

Using Mascot Scores As Semiquantitative Measure In Proteomic Analyses Of<br />

Short-Chain Acyl-Coa Dehydrogenase (Scad) Deficiency Patients<br />

Søren Vang (Research Unit for Molecular Medicine, DENMARK), Christina Bak<br />

Pedersen, Johan Palmfeldt, Niels Gregersen<br />

Evaluating Isobaric Tandem Mass Tags For Quantitative Peptidomics.<br />

Peter Verhaert (Delft University of Technology, Department of Biotechnology, THE<br />

NETHERLANDS), Martijn Pinkse<br />

Profiling Of A1 Mes-C-Myc Mouse Embryonic Mesencephalon Cells By Data<br />

Independent Lc-Ms<br />

Angela Chambery, Johannes Vissers (Waters Corporation, Ms Technologies Center,<br />

UNITED KINGDOM), James I. Langridge, Luca Colucci-D’Amato, <strong>August</strong>o Parente<br />

Automated Optimization Of Triple Quadrupole Parameters For Nanoflow Lc/Ms<br />

Of Peptides<br />

Keith Waddell (Agilent Technologies, UNITED STATES), Christine Miller, Ning Tang, S Torvi<br />

Multiple Approaches To The Identification And Quantification Of The Human Liver<br />

Proteome<br />

Yuqin Wang (Swansea University, UNITED KINGDOM), Cathrin Sibert, Brian<br />

Davidson, Barry Fuller, William Griffiths<br />

Quantitative Proteomics By Lc-Ms/Ms Multiplex Analysis Of Guanidino-Labeled<br />

(Glad) Samples<br />

Patrice Waridel (University of Lausanne, SWITZERLAND), Francesco Brancia,<br />

Jachen Barblan, Manfredo Quadroni<br />

Withdrawn<br />

Transformation Of Ion Intensity Improves Peptide Quantification<br />

Xiaoyong Wu (Mcgill University, CANADA), Brian Carrillo, Pascal Pleynet, Daniel<br />

Boismenu, Sylvie Laboissiere, Robert Kearney, Robert Nadon<br />

150 151


Other<br />

P-WED-292<br />

P-WED-293<br />

Protease Proteomics - Meprin Alpha Releases Vesicular Integral-Membrane<br />

Protein Vip36<br />

Daniel Ambort (Department of Medical Biochemistry, University of Gothenburg,<br />

Sweden / Institute of Biochemistry and Molecular Medicine, University of Berne,<br />

SWITZERLAND), Daniel Stalder, Manfred Heller, Erwin E. Sterchi<br />

The Development Of Novel Computer Approaches For Diseases At Its<br />

Development In Lipid Peroxidation.<br />

Sukiasyan Astghik (State Engineering University of Armenia, Armenia), Kirakosyan<br />

Armen, Tadevosyan Artashes, Humbardzumyan Armen<br />

P-WED-304<br />

P-WED-305<br />

Proteomic Analysis Of Exosomes Secreted By Hepatocytes<br />

Javier Conde-Vancells, Felix Elortza (Proteomics Unit, Cic Biogune , SPAIN), Eva<br />

Rodríguez-Suárez, Rune Matthiesen, Nieves Embade, Esperanza González, Jose M.<br />

Mato, Juan M. Falcón-Pérez<br />

A Proteomic Approach On The Immunomodulatory Effects Of Tx527, A<br />

1,25-Dihydroxyvitamin D3 Analogue, In Human Dendritic Cells And T<br />

Lymphocytes<br />

Gabriela Ferreira (Laboratoryof Experimental Medicine and Endocrinology, Catholic<br />

University of Leuven (Kul), BELGIUM), Femke Baeke, Lut Overbergh, Evelyne van<br />

Etten, Kasper Lage, Daniel Hansen, Etienne Waelkens, Christopher Workman,<br />

Chantal Mathieu<br />

P-WED-294<br />

Penguin Plasma Proteomics: Differential Analyses According To The Metabolic Status<br />

Fabrice Bertile (Iphc-Dsa, Ulp, Cnrs, FRANCE), Laetitia Fouillen, Thierry Raclot,<br />

Alain van Dorsselaer<br />

P-WED-306<br />

Lc-Ms/Ms-Based Proteome Profiling In Dahnia Pulex And Daphnia Longicephala.<br />

Thomas Frohlich (University Munich - Genecenter - Lafuga, GERMANY), Georg J.<br />

Arnold, Christian Laforsch<br />

P-WED-295<br />

Two-Dimensional Protein Profile Of Human Follicular Fluid: Pregnant X Non-Pregnant<br />

Ricardo Bertolla (Federal University of Sao Paulo, BRAZIL), Paula Lopes, Edson Lo<br />

Turco, Agnaldo Cedenho<br />

P-WED-307<br />

Rapid On-Membrane Profiling Of Phosphoproteins Using The Piezoelectric<br />

Technology<br />

Masaru Furuta (Shimadzu Corporation, JAPAN), Tsuyoshi Nakanishi, Eiji Ando<br />

P-WED-296<br />

P-WED-297<br />

P-WED-298<br />

The Human Proteome Initiative, Providing A Complete Set Of Human Protein<br />

Sequences<br />

Lionel Breuza (Swiss Institute of Bioinformatics (Sib), SWITZERLAND), Amos<br />

Bairoch, Uniprot Consortium<br />

Complete De Novo Sequencing Of Allergenic Proteins Using Bottom-Up<br />

Proteomics And Accurate Moecular Mass Measurement By Fticr-Ms<br />

Monica Carrera (Instituto de Investigaciones Marinas (Iim), Consejo Superior de<br />

Investigaciones Cientificas (Csic), SPAIN), Benito Canas, Lorena Barros, Jesus<br />

Vazquez, Jose Manuel Gallardo<br />

Identification Of Ubiquitination Sites And Chain Architecture: The Hunt For Red<br />

K29<br />

Emma Carrick (Mrc Ppu, University of Dundee, UNITED KINGDOM), Nick Morrice<br />

P-WED-308<br />

P-WED-309<br />

P-WED-310<br />

Hepatocystin Is Not Secreted In Cyst Fluid Of Hepatocystin Mutant Polycystic<br />

Livers<br />

Esmé Waanders, Anke L.L. Lameris, Huub J.M. op den Camp, Wendy Pluk, Jolein Gloerich<br />

(Nijmegen Proteomics Facility, Radboud University Nijmegen Medical Center, THE<br />

NETHERLANDS), Simon P. Strijk, Joost P.H. Drenth<br />

Integration Of Proteomics With Metalloproteomics (Metallomics) And Genomics<br />

In Sequenced Model Organisms<br />

Jose Luis Gomez-Ariza (Universidad de Huelva, SPAIN)<br />

Integrated Plant Metabolomics By Fourier Transform Ion Cyclotron Resonance<br />

Mass Spectrometry<br />

Jun Han (University of Victoria – Genome Bc Proteomics Centre, CANADA), Ryan M.<br />

Danell, Dustin Lippert, Monica Elloitt, Jörg Bohlmann, Christoph H. Borchers<br />

P-WED-299<br />

P-WED-300<br />

P-WED-301<br />

P-WED-302<br />

Hepcidin Measurement, Using Seldi-Tof-Ms, In Clinically Relevant Samples<br />

Annalisa Castagna (University of Verona, ITALY), Natascia Campostrini, Claudia<br />

Bozzini, Michela Pasino, Fabiana Busti, Roberto Corrocher, Domenico Girelli<br />

Functional Role Of 0-Glcnac Modification On Nfkappab<br />

Jin Won Cho (Yonsei Univ. Dept of Biology, KOREA), Won Ho Yang, Sang Yoon Park,<br />

Do Hyun Kim<br />

Protein Microarray Based Target Identification Of Bioactive Protein<br />

Yoon Sun Cho (Chemical Genomics Laboratory, Department of Biotechnology, College<br />

of Life Science and Biotechnology, Yonsei University, KOREA), Hye Jin Jung, Ho<br />

Jeong Kwon, Jung Min Han, Sung Hoon Kim<br />

Proteome Analysis Of Sulfur-Reducing Hyperthermophilic Archaea Thermococcus<br />

Onnurineus Na1<br />

Chi-Won Choi (Korea Basic Science Institute, KOREA), Sung Ho Yun, Sang Oh Kwon,<br />

Sung Gyun Kang, Jung-Hyun Lee, Gun Wook Park, Jin Young Kim, Jong-Soon Choi,<br />

Seung Il Kim<br />

P-WED-311<br />

P-WED-312<br />

P-WED-313<br />

P-WED-314<br />

Method To Identify And Isolate Maturing B Cells In Neonatal Mice<br />

Jenny Hansson (Department of Biochemistry and Molecular Biology, University of<br />

Southern Denmark, Denmark / Nestlé Research Center, SWITZERLAND), Manuel<br />

Oliveira, Laurent Favre, Jalil Benyacoub, Stephanie Blum, Ole N. Jensen, Martin<br />

Kussmann<br />

Mass Spectrometric Analysis Of Sumoylation Of The Transcriptional Repressor Tel<br />

Paul Hensbergen (Lumc, Biomolecular Mass Spectrometry Unit, Dept. of<br />

Parasitology, THE NETHERLANDS), Guy Roukens, Mariam Halloul-Ramdhani, Alfred<br />

Vertegaal, Crina Balog, André Deelder, David Baker<br />

Engineered Antibody Mimics Selected Against Novel Proteomic Biomarkers Are<br />

High-Value Reagents<br />

Peter Hudson (Csiro, AUSTRALIA)<br />

Using Targeted Proteomics To Id Cellular Targets Of Oxidation In Type 1 Diabetes<br />

Karen Jonscher (University of Colorado Denver, UNITED STATES), Miriam Kornfeld,<br />

Gloria Ortiz, Bj Ada, Bjorn Schneidewind, Sonia Flores<br />

P-WED-303<br />

Pig As A Model Organism For Human Diseases<br />

Marianne Danielsen (University of Aarhus, DENMARK), Emøke Bendixen, Marius<br />

Codrea, Bent Jensen, Lone Rasmussen, Knud Larsen, Christian Bendixen, Jan<br />

Stagsted, Per Sangild, Andrew Kessel<br />

P-WED-315<br />

Identification Of Ca-Binding Proteins In Anabaena Sp Pcc7120 Using Proteomic<br />

Techniques<br />

Alberto Jorge-Garcia (Centro de Biologia Molecular Severo Ochoa, SPAIN), Francisco<br />

Leganes, Francisca Fernandez-Pinas<br />

152 153


P-WED-316<br />

P-WED-317<br />

Withdrawn<br />

Cold Acclimation In Synechocystis Pcc6803<br />

John Rowland (Durham University / Nepaf, UNITED KINGDOM), Joanne Robson,<br />

Jogadhenu Prakash, Glen Kemp, Achim Treumann, Norio Murata<br />

P-WED-328<br />

P-WED-329<br />

Full Genome Analysis Of T-Regulatory Cells Isolated From Cancer Patients<br />

Alexei Lupatov (V.N. Orechovich Institute of Biomedical Chemistry Rams , RUSSIAN<br />

FEDERATION)<br />

Withdrawn<br />

P-WED-318<br />

P-WED-3<strong>19</strong><br />

P-WED-320<br />

P-WED-321<br />

P-WED-322<br />

Proteomics Analysis For Vibration Effect On Acl Cells<br />

Ji-Hye Kim (Korea University, KOREA), Eun-Jeong So, Hyun-Jung Kim, Young-Kwon<br />

Seo, Jung-Keuk Park, Chan-Wha Kim<br />

Protein Identification By Means Of Coherent Two-Dimensional Infrared<br />

Spectroscopy<br />

David Klug (Imperial College London, UNITED KINGDOM), Frederic Fournier, Elizabeth<br />

Gardner, Paul Donaldson, Christian Loeffeld, Rui Guo, Keith Willison<br />

Investigation Of Low Culture Temperature Response In Cho-K1 Cells Using<br />

Proteomics Tools<br />

Niraj Kumar (National Institute for Cellular Biotechnology, Ireland), Patrick<br />

Gammell, Paula Meleady, Michael Henry, Niall Barron, Martin Clynes<br />

Exploration Of The Human Chondrocyte Proteome By A Dual Prefractionation<br />

Approach<br />

Stijn Lambrecht (Ghent University - Department of Rheumatology / Laboratory for<br />

Pharmaceutical Biotechnology, BELGIUM), Maarten Dhaenens, Gust Verbruggen,<br />

Dirk Elewaut, Dieter Deforce<br />

Identification Of Tomato Fruit Allergen Profiles By Two Proteomics Approaches<br />

Karola Lehmann (Proteome Factory Ag, GERMANY), Sabine Dölle, Margitta Worm,<br />

Dietmar Schwarz, Philipp Franken, Olivia Bässler, Wolfram Weckwerth, Christian<br />

Scheler<br />

P-WED-330<br />

P-WED-331<br />

P-WED-332<br />

P-WED-333<br />

P-WED-334<br />

Identification Of Delta Antigen Nuclear Localization Signal Interacting Cellular<br />

Proteins<br />

Marta Mendes (Unidade de Biologia Molecular, Centro de Malária E Outras Doenças<br />

Tropicais, Instituto de Higiene E Medicina Tropical, Universidade Nova de Lisboa,<br />

PORTUGAL), Carolina Alves, Sérgio Mota, Natália Freitas, Ana Casaca, Déborah<br />

Penque, Celso Cunha<br />

Validation Of Procedures For Ms Based Database Search Protocols For Protein<br />

Identification<br />

Jackie Mosely (Durham University, UNITED KINGDOM), Gavin O’Connor, Simon<br />

Cowen, Sarah Williams<br />

Role Of Albumin Precursor And Hsp70 Proteins In Wound Healing Of Corneal<br />

Epithelial Cells<br />

Shamim Mushtaq (University of Karachi, Pakistan)<br />

Analysis Of Ubr1 Targets In Patients With Johanson-Blizzard Syndrome And A<br />

Murine Model<br />

Karanam Narasimha Kumar (Department of Medicine A / Institute of Functional Genomics,<br />

Ernst-Moritz-Arndt-University Greifswald, GERMANY), Martin Zenker, Alexander<br />

Varshavsky, Christian Scharf, Elke Hammer, Markus M. Lerch, Uwe Völker, Julia Mayerle<br />

Proteomics Analysis Of Human Endothelial Cells Exposed To Mobile Phone Radiation<br />

Reetta Nylund (Stuk, FINLAND), Hanna Tammio, Niels Kuster, Dariusz Leszczynski<br />

P-WED-323<br />

P-WED-324<br />

Proteomic Analysis Of The Schistosome Proteins Released Into Host Serum<br />

Feng Liu (Shanghai-Most Key Laboratory of Health and Disease Genomics, Chinese<br />

National Human Genome Center at Shanghai / Shanghai Jiao Tong University School<br />

Of Medicine, CHINA), Wei Hu, Shu-Jian Cui, Zhi-Qin Wang, Ze-Guang Han<br />

Two-Dimensional Protein Profile Of Human Follicular Fluid: Endometriosis X Good<br />

Responders<br />

Edson lo Turco (Federal University of Sao Paulo, BRAZIL), Paula Lopes, Ricardo<br />

Bertolla, Maisa Sakata, Ismael Silva, Agnaldo Cedenho<br />

P-WED-335<br />

P-WED-336<br />

Comparison Of Carbonylated Peptide Enrichment Methods Optimized For Mass<br />

Spectrometry<br />

Angela Pereira da Rocha (Protein Research Group, Department of Biochemistry and<br />

Molecular Biology, University of Southern Denmark, DENMARK), Adelina Rogowska-<br />

Wrzesinska, Kenneth Bendix Jensen, Peter Roepstorff<br />

2-De Protein Analysis In Carboplatin Treated Human Renal Tubular Epithelial Cells<br />

Juliana Perez (Federal University of Sao Paulo, BRAZIL), Maisa Sakata, Ricardo<br />

Bertolla, Dulce Casarini<br />

P-WED-325<br />

P-WED-326<br />

P-WED-327<br />

Automated “In-Gel” And “On-Membrane” Digest For High-throughput Protein<br />

Identification<br />

Bjoern H. Bender (Institute of Biochemistry, University Giessen, GERMANY), Anne<br />

Wagner, Julia Grabitzki, Peter Kiesau, Brian Mcglothlen, Carsten Mang, Peter Engel,<br />

Guenter Lochnit<br />

Interfacing Capillary Electrophoresis And 2d-Infrared Spectroscopy For High<br />

Throughput Proteomics<br />

Christian Loeffeld (Imperial College London, UNITED KINGDOM), Frederic Fournier,<br />

Paul Donaldson, Miriam Goyder, Rafal Marszalek, Bo Zhang, Christopher Barnett,<br />

Keith Willison, David Klug<br />

Two-Dimensional Protein Profile Of Human Follicular Fluid: Good X Poor Ovarian<br />

Responders<br />

Paula Lopes (Federal University of Sao Paulo, BRAZIL), Ricardo Bertolla, Edson Lo<br />

Turco, Juliana Perez, Dulce Casarini, Agnaldo Cedenho<br />

P-WED-337<br />

P-WED-338<br />

P-WED-339<br />

P-WED-340<br />

P-WED-341<br />

Copmparision Between Different Protein Dectection Techniques For<br />

Polyacrylamid Gels<br />

Mario Pink (Institute of Hygiene and Occupational Medicine, University Hospital<br />

Essen, GERMANY), Albert W. Rettenmeier, Simone Schmitz-Spanke<br />

Combined Transcriptome/Peptidome Analysis From Odorrana Schmackeri, The<br />

Chinese Odorous Frog<br />

Martijn Pinkse (Delft University of Technology, Department of Biotechnology, THE<br />

NETHERLANDS), Geisa Caprini, Tienbao Chen, Peter Verhaert, Christopher Shaw<br />

Establishment Of A High-Throughput Generation System Of Monoclonal<br />

Antibodies Using Multiplexed Immunization And Antigen Microarrays<br />

Feifei Qi (Beijing Proteome Research Center, CHINA)<br />

Withdrawn<br />

Identification Of Novel Human Adipokines<br />

Anja Rosenow (Maastricht University, THE NETHERLANDS), Edwin Mariman, Johan<br />

Renes<br />

154 155


P-WED-342<br />

P-WED-343<br />

P-WED-344<br />

Mitochondrial Proteomic Alterations In Osteoarthritic Human Articular<br />

ChondrOcytes<br />

Cristina Ruiz-Romero (Osteoarticular and Aging Research Lab, Proteomics Unit.<br />

Biomedical Research Center, Ch Universitario Juan Canalejo, SPAIN), Vanessa<br />

Carreira, Silvia Remeseiro, Valentina Calamia, Jesús Mateos, María Fernández,<br />

Fausto Galdo, Fj Blanco<br />

Proteomic Analysis Of Human Chondrocytes Treated With Glucosamine And<br />

Chondroitin Sulfate<br />

V Calamia (Osteoarticular and Aging Research Laboratory. Proteomics Unit.<br />

Biomedical Research Center. Ch Universitario Juan Canalejo, SPAIN), C Ruiz-Romero,<br />

V Carreira, J Mateos, B Cillero-Pastor, E Montell, J Verges, Fj Blanco<br />

Differential Effects Of Il-1beta And Tnf-Alpha In The Protein Profile Of Human<br />

Normal Chondrocytes<br />

B Cillero-Pastor (Osteoarticular and Aging Research Lab. Biomedical Research<br />

Center, C.H.U. Juan Canalejo, SPAIN), MJ López-Armada, C Ruiz-Romero, J Mateos,<br />

M Lires-Deán, B Caramés, B Lema, FJ Blanco<br />

P-WED-353<br />

P-WED-354<br />

P-WED-355<br />

And Imaging Analysis For Size-Dependent Biological Behavior Of Silica-Nanoparticles<br />

Tomoaki Yoshikawa (Universitylaboratory of Pharmaceutical Proteomics, National<br />

Institute of Biomedical Innovation, JAPAN), Hiromi Nabeshi, Toshiki Sugita, Kazuya<br />

Nagano, Shin-Ichi Tsunoda, Yasuo Tsutsumi<br />

Placental Plasma Proteome Study Of Human Parturition<br />

Wei Yuan (University of Bristol, UNITED KINGDOM), Kate Heesom, Neil Avent,<br />

Andrés López Bernal<br />

Sensitive Detection Of Oligomeric Conformations Of Proteins By Proximity<br />

Ligation Assay<br />

C Annink (Uppsala University, SWEDEN), H Englund, S Darmanis, FE Pettersson,<br />

O Söderberg, D Sehlin, A Lord, L Nilsson, L Lannfelt, U Landegren and M Kamali-M<br />

P-WED-345<br />

Role Of Magnesium Supplementation In Post-Ischemic Acute Renal Failure<br />

Maisa Sakata (Federal University of Sao Paulo, BRAZIL), Juliana Perez, Ricardo<br />

Bertolla, Dulce Casarini<br />

P-WED-346<br />

Analysis Of Rho Gtpase Activation And Inhibition In A Multiplexed, Miniaturised<br />

Format<br />

Thomas Joos, Nicole Schneiderhan-Marra, Michael Schmohl (Nmi Natural and<br />

Medical Sciences Institute at The University of Tubingen, GERMANY), Stefanie<br />

Rimmele, Oliver Poetz, Peter Gierschik, Yoel Kloog<br />

P-WED-347<br />

Assessment Of Protein Alterations In Platelets Caused By Uvc-, Uvb- And<br />

Gamma-Irradiation<br />

Leif Steil (Interfaculty Institute of Genetics and Functional Genomics, Ernst-Moritz-<br />

Arndt University Greifswald, GERMANY), Thomas Thiele, Elke Hammer, Harald Mohr,<br />

Ulrich Pohl, Thomas Müller, Andreas Greinacher, Uwe Völker<br />

P-WED-348<br />

Proteomic Analysis Of Calcium Oxalate Monohydrate Crystal-Induced<br />

Cytotoxicity In Distal Renal Tubular Cells<br />

Visith Thongboonkerd (Medical Proteomics Unit & Medical Molecular Biology Unit,<br />

Office for Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol<br />

University, Thailand), Theptida SemaNgoen, Supachok Sinchaikul, Shui-Tein Chen<br />

P-WED-349<br />

A High-Throughput Strategy For Validation Of Antibodies Towards Unknown<br />

Proteins.<br />

Kenneth Wester (Dept of Genetics & Pathology, Uppsala University, SWEDEN), Anna<br />

Asplund, Caroline Kampf, Mathias Uhlen, Sophia Hober, Henrik Wernerus, Fredrik<br />

Ponten<br />

P-WED-350<br />

Fluorescent Proteins, Ocean’s Gift To Research And Biotechnology<br />

Krzysztof Wrzesinski (Protein Research Group, Department for Biochemistry and<br />

Molecular Biology, University of Southern Denmark, DENMARK), Nicolai Bache,<br />

Martin Røssel Larsen, Ole Thastrup, Peter Roepstorff Roepstorff<br />

P-WED-351<br />

Direct Visualization Of Fluorescent Signals In Protein Gels Using A Backlit Blue<br />

Light Plate<br />

Szu-Yu Wu (Institute of Applied Science and Engineering, Fu-Jen Catholic University,<br />

TAIWAN), Li-Te Chin, Li-Ming Chen, Han-Min Chen<br />

P-WED-352<br />

Multistep Approach For Ptms Analysis In An In-Gel Digest With MALDI-Ms/Ms<br />

Yuzo Yamazaki (Shimadzu Corporation, JAPAN), Masaki Yamada<br />

156 157


Look for career opportunities at<br />

www.netherlandsproteomicscentre.nl<br />

High-level proteomics research,<br />

technology development & transfer<br />

for biological and biomedical applications<br />

www.netherlandsproteomicscentre.nl<br />

Agilent in Proteomics<br />

Unique HPLC-Chip LCMS solutions for faster, easier<br />

and more flexible answers for proteomics workflow<br />

© Agilent Technologies Inc., 2008<br />

Our measure is your success.<br />

products | applications | <strong>software</strong> | services<br />

Join Agilent<br />

for an informative workshop on<br />

Proteomics Workflows<br />

Monday <strong>August</strong> 18 th , 2008<br />

12:30 – 14:00, Room B<br />

For registration, visit the Agilent display at booth #32/33.<br />

The New HPLC-CHIP 6530 QTOF<br />

and 6460 Triple Quadrupole<br />

Solutions for true ‘high def’<br />

accurate-mass protein ID and<br />

sensitive targeted peptide<br />

quantitation<br />

Information for Oral and<br />

Poster Presenters<br />

Oral Presentations<br />

Speakers should make sure that at least 4 hours before the start of the session,<br />

their PowerPoint presentations are uploaded in the Speaker Ready Room. Computers<br />

are available for a last minute check of the presentation and a technician will be there<br />

to assist.<br />

The Speaker Ready Room is located in Room M in the Forum Centre<br />

and will be open at the following hours:<br />

Saturday, 16 <strong>August</strong> 08.30 - 18.30 hrs<br />

Sunday, 17 <strong>August</strong> 08.30 - 17.00 hrs<br />

Monday, 18 <strong>August</strong> 06.30 - <strong>19</strong>.00 hrs<br />

<strong>Tuesday</strong>, <strong>19</strong> <strong>August</strong> 06.30 - 20.00 hrs<br />

Wednesday, 20 <strong>August</strong> 06.30 - 17.00 hrs<br />

Speakers are requested to be present in the meeting room at least 10 minutes prior<br />

to the start of the session to meet the chairperson and to check with the audio<br />

visual assistant. All meeting rooms are equipped with data projection, a PC and a<br />

laser pointer. Speakers are not allowed to bring their own laptop. The chairperson will<br />

time all presentations. It is essential that all presentations are kept to the program<br />

timetable.<br />

Poster Presentations<br />

Posters will be on display in the exhibition and poster area (Hall 10 of the RAI Convention<br />

Centre). From Monday to Wednesday, posters can be viewed during meeting breaks<br />

which are scheduled daily on the following hours:<br />

Morning break<br />

09.30 - 11.00 hrs<br />

Lunch break<br />

12.30 - 14.00 hrs<br />

Afternoon break 15.30 - 16.00 hrs<br />

We would like to ask all poster presenters to be present at their poster at least<br />

during the morning and afternoon break.<br />

All posters will be on display for one day only, either on Monday, <strong>Tuesday</strong> or Wednesday.<br />

Posters will be numbered as P-MON-#, P-TUE-# and P-WED-# respectively (see pages<br />

68 - 157).<br />

Posters must be put on the allocated poster board on the day of presentation between<br />

07.30 and 09.00 hrs. Poster numbers are printed on the poster boards. Fixing material<br />

will be available in the poster area. Posters should be removed from the poster boards<br />

between 16.00 and <strong>19</strong>.00 hrs.<br />

The organization will not be responsible for posters that are not removed in time, they<br />

will be discarded after the congress.<br />

158 159


Exhibition Information<br />

The 7th HUPO Annual World Congress expresses its warm thanks to our Exhibitors<br />

for supporting the Congress. We encourage all delegates to visit the Exhibition and to<br />

learn more about the products and services on show. The Exhibition is located in Hall<br />

10, accessible from the first floor of the congress centre. The booth numbers can be<br />

found on page 20 in this Final Program.<br />

Exhibition opening hours:<br />

Monday 18 <strong>August</strong><br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />

Wednesday 20 <strong>August</strong><br />

09.30 - <strong>19</strong>.00 hrs<br />

09.30 - 20.00 hrs<br />

09.30 - 16.00 hrs<br />

Exhibition Information / Registration Desk opening hours:<br />

Saturday 16 <strong>August</strong> 13.00 - 20.00 hrs<br />

Sunday 17 <strong>August</strong> 10.00 - 20.00 hrs<br />

Monday 18 <strong>August</strong> 08.00 - 13.00 hrs<br />

Wednesday 20 <strong>August</strong> 16.00 - 18.00 hrs<br />

General Information<br />

Abstracts<br />

The abstracts are available on a USB stick which is included in the registration package<br />

for registered delegates.<br />

Beach South<br />

Behind the Auditorium Centre you will find this upmarket city beach ‘Strand Zuid’<br />

(Beach South), with elegant beach furniture and a nice bar. It borders the Beatrix Park<br />

pond, no swimming is allowed but showers are available. DJ’s are playing there during<br />

the weekends. It is open during the Congress for lunch, dinner or just to relax!<br />

Coffee and tea breaks<br />

For registered participants wearing their name badges, coffee and tea during the<br />

breaks are included in the fee. The coffee breaks on Monday are sponsored by:<br />

Cloakroom facilities<br />

A paid cloakroom is situated at the Forum Lounge, near the registration desk. The<br />

cloakroom will be guarded during Congress hours. The organizers cannot accept liability<br />

for loss or damage to property.<br />

Currency and banking<br />

The local currency is the euro (Eur/€). € 1 = 100 cents. Visa, MasterCard and<br />

American Express are accepted at the Registration Desk. Foreign currency will not be<br />

accepted. You are requested to pay with credit card or cash in Euros only. In general,<br />

all major credit cards are accepted for payment in hotels, restaurants and shops.<br />

There is an ATM machine in the RAI Convention Center, accessible via the entrance K2<br />

(exit the Auditorium Center, keep to the left and walk up to the corner, turn left; the<br />

first entrance is K2. Please ask the receptionist for further directions). There is also<br />

an ATM machine in the square opposite the RAI (ABN AMRO Bank, Scheldeplein 1-5).<br />

Banks are open Monday to Friday from 10.00 - 16.00 hrs.<br />

Disclaimer<br />

All best endeavours will be made to present the program as printed. However, the<br />

organizers reserve the right to alter or cancel, without prior notice, any arrangements,<br />

timetables, plans or other items relating directly or indirectly to the Congress for any<br />

cause beyond it’s reasonable control. In registering for the 7th HUPO Annual World<br />

Congress you agree that neither the organizing committee nor the congress secretariat<br />

accept any liability whatsoever. The organizers accept no liability for personal injuries<br />

or loss, of any nature whatsoever, or for loss or damage to property either during or<br />

as a result of the Congress. Participation is completely at the delegate’s own risk.<br />

The organizers will not be liable and will not compensate for any damage incurred to<br />

delegates during the Congress. Dutch laws apply. Delegates are advised to acquire<br />

their own travel insurance and to extend their policy to cover personal possessions<br />

160 161


as the Congress does not cover individuals against cancellation or bookings or theft<br />

or damage to belongings.<br />

Dress code<br />

Recommended dress code for the Congress and all social functions is smart casual.<br />

Electricity supply<br />

Electricity in the Netherlands is supplied at 220V - 50Hz AC. USA, English and some<br />

other foreign appliances require an adapter for the voltage as well as an adapter for<br />

the plug. There are no adapters available at the RAI Convention Centre.<br />

Emergencies<br />

If you or any other delegate is unwell, an accident or any other emergency occurs,<br />

while at the Amsterdam RAI Convention Centre, please contact the registration desk<br />

or any staff member.<br />

Internet Corner sponsored by WATERS:<br />

An Internet corner is at the disposal of the Congress delegates during Congress<br />

opening hours. Wireless internet will also be provided free of charge in this area. No<br />

access code required. Just select the HUPO 2008 network.<br />

Language<br />

The official congress language will be English. No translation arrangements will be made.<br />

Lost Property<br />

If you see any unattended parcel, please report to one of the Congress staff members.<br />

Should you loose anything at the Amsterdam RAI Convention Centre, please enquire<br />

at the Registration Desk.<br />

Lunches<br />

Lunch can be bought in the exhibition hall 10 or at Beach South.<br />

Messages<br />

Messages for delegates should be handed in at the Registration Desk. Notification<br />

of messages will be displayed on the message board next to the Registration Desk.<br />

Please check the board daily and pick up your messages – they may be urgent.<br />

Mobile phones<br />

Mobile phones must be switched off in the meeting rooms.<br />

Name badges and tickets<br />

For security purposes, delegates and exhibitors must wear their name badges at all<br />

times during the Congress. Entrance to the Amsterdam RAI Convention Centre will be<br />

limited to badge holders only. Replacement of lost name badges can be requested at the<br />

registration desk (costs € 25). Tickets for social <strong>event</strong>s and excursions will be issued to<br />

delegates who have booked for these <strong>event</strong>s. Please present your tickets at these <strong>event</strong>s<br />

and excursions.<br />

Orange Student Brigade<br />

A team of enthusiastic students will be at your service. During Congress hours, they<br />

will provide hospitality support and steward services. They will also serve in most<br />

of the meeting rooms as technical assistants and can be easily recognized by their<br />

orange shirts.<br />

Program changes<br />

The organizers cannot accept liability for any changes in the program due to external<br />

or unforeseen circumstances.<br />

Public Transport<br />

Amsterdam is a very compact city where your destination usually will not be at a great<br />

distance. Therefore, Amsterdam is ideal for getting around by foot, bicycle or public<br />

transport. There is a dense public transport system and tram, metro or bus stops<br />

are usually around the corner. Cars are less suitable for navigating in Amsterdam.<br />

Moreover, parking must be paid for in almost the entire city and the rates can be<br />

substantial.<br />

How to reach the Amsterdam RAI Convention Center:<br />

From Amsterdam RAI railway Station: from this station it is a short walk (8<br />

minutes) to the Convention Center. You can also take tram 4; first stop in front of<br />

the Convention Center.<br />

From the Central railway Station: tram 4<br />

From the Amstel railway Station: bus no. 15 or 62 to the Amsterdam RAI railway<br />

Station.<br />

There will be no shuttle service available between Schiphol Amsterdam International<br />

Airport, the Amsterdam RAI or the Congress hotels.<br />

Registration and Information:<br />

The registration desk will be located at the ground floor of the Forum Center<br />

(Entrance E of The Rai Convention Center).<br />

Opening hours:<br />

Saturday 16 <strong>August</strong><br />

Sunday 17 <strong>August</strong><br />

Monday 18 <strong>August</strong><br />

<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />

Wednesday 20 <strong>August</strong><br />

09.00 - <strong>19</strong>.00 hrs<br />

08.30 - 18.00 hrs<br />

07.30 - 18.00 hrs*<br />

07.30 - 20.00 hrs*<br />

07.30 - 18.30 hrs*<br />

* For Corporate Workshops registration from 06.30 hrs.<br />

Registered participants and students are entitled to:<br />

Opening ceremony and welcome reception<br />

Attendance to scientific sessions<br />

Entrance to the exhibition<br />

All congress documents<br />

Coffee and tea during the breaks<br />

162 163


Registered accompanying persons are entitled to:<br />

Opening ceremony and welcome reception<br />

Amsterdam city tour<br />

Services for the Disabled<br />

All the rooms at the Congress venue are fully accessible to delegates with<br />

disabilities.<br />

Smoking Policy<br />

In the RAI Convention Centre, smoking is prohibited by law. Smoking is only permitted<br />

in a few designated areas outside the building.<br />

Shopping<br />

Most shops are open from <strong>Tuesday</strong> through Friday from 9.00 to 18.00 hours, Saturdays<br />

from 09.00 to 17.00 hours. On Mondays, many shops are closed in the morning. They<br />

open between 11.00 and 13.00 hours and close at 18.00 hours. Evening shopping<br />

(until 21.00 hours) is on Thursdays and many shops in the city centre open on Sundays<br />

from 12.00 to 17.00 hours.<br />

Time<br />

Amsterdam is 1 hour ahead of Greenwich Mean Time.<br />

Tipping<br />

Service is always included. However, it is customary to tip in restaurants and when<br />

paying for taxi’s. As a general rule tipping between 5 - 10% should be adequate.<br />

Taxis<br />

Taxis can be ordered at the Porter’s Desk in the access hall of the Auditorium.<br />

Social Program<br />

opening ceremony & welcome reception<br />

Date:<br />

Time:<br />

Location:<br />

Dress code:<br />

Price:<br />

Monday 18 <strong>August</strong><br />

16:00 - <strong>19</strong>:00 hrs<br />

Amsterdam RAI Convention Centre, Auditorium & Exhibition Area<br />

Smart casual<br />

included in the registration fee for registered participants and<br />

registered accompanying persons.<br />

The Opening Ceremony will be held in the Auditorium and opened by eminent<br />

representatives of the international scientific community. Don’t miss this opportunity<br />

to enjoy this mix of Dutch and international cultural outings! The Opening Ceremony will<br />

be followed by the welcome reception.<br />

A welcome reception will be offered to delegates and registered accompanying persons<br />

at the Exhibition area. Just enjoy each other’s company and mingle while enjoying<br />

typical Dutch snacks and entertainment. All participants are invited to attend this<br />

reception of the 7th Annual HUPO Congress so bring your (registered) family and<br />

friends and have a good start of the congress!<br />

congress dinner<br />

Date:<br />

Wednesday 20 <strong>August</strong><br />

Time:<br />

<strong>19</strong>:00 - 23:00 hrs<br />

Location: Stopera (acronym for “Stadhuis”=City Hall and the “Opera”=Theatre)<br />

Departure: By canal boat from RAI Harbour at 18.15 hrs.<br />

Dress code: Smart casual<br />

Price: €65,00<br />

We would like to invite all participants to attend the 7th Annual HUPO Congress<br />

Dinner. Join us and all the other delegates from around the world on this splendid,<br />

colorful evening in the heart of Amsterdam. The Stopera is beautifully located right<br />

on the Amstel river, and the high open foyers overlook the historic panorama of<br />

Amsterdam.<br />

164 165


Accompanying Persons<br />

Tour / Excursion *<br />

(included in the Accompanying Person’s fee)<br />

This tour includes a most panoramic drive through the centre and the modern suburbs,<br />

passing the most important monuments and sights including a stop at the Rembrandt<br />

windmill. The excursion will end with a canal cruise through the city of Amsterdam and<br />

to admire the famous 17th century merchant houses with its different gable structures<br />

and the numerous bridges which makes Amsterdam ‘The Venice of the North’.<br />

Date: Monday 18 <strong>August</strong><br />

Time: 12:30 - 15:30 hrs<br />

Rate: €35,00 per person<br />

Amsterdam city tour<br />

Tours should have been booked in advance when registering for the congress<br />

Registration and cancellation conditions are applied to the tours and excursions.<br />

The cost of tickets cannot be refunded if you do not take part or have not taken<br />

part in the tour / excursion.<br />

* Due to an insufficient number of registrations, the following tours had to be cancelled: Aalsmeer, Delft &<br />

the Hague; Rotterdam and Kinderdijk Windmills; Zaanse Schans; Castles & River Vecht. If you have already<br />

registered for one of those, you are most welcome to join the other tour. Pease contact the Registration Desk<br />

for more information.<br />

Exhibitor and Sponsor Listing<br />

Abfrontier Co. Ltd<br />

Stand: 070<br />

Korea<br />

Website: www.abfrontier.com<br />

Agilent Technologies<br />

Stand: 032<br />

Website: www.agilent.com/chem<br />

American Chemical Society<br />

Stand: 027<br />

USA<br />

Website: http://pubs.acs.org<br />

Applied Biosystems / MDS Analytical Technologies<br />

Stand: 063<br />

USA<br />

Website: www.appliedbiosystems.com<br />

Atlas Antibodies<br />

Stand: 025<br />

Sweden<br />

Website: www.atlasantibodies.com<br />

A Publication of the American Chemical Society<br />

Aushon BioSystems<br />

Stand: 115<br />

USA<br />

Website: www.aushon.com<br />

Australian Proteome Analysis Facility Ltd<br />

Stand: 008<br />

Australia<br />

Website: www.proteome.org.au<br />

APAF<br />

australian proteome<br />

anaylsis facility<br />

Axela Inc.<br />

Stand: 104<br />

Canada<br />

Website: www.axela.com<br />

166 167


BD Biosciences<br />

Stand: 082<br />

Belgium<br />

Website: www.bdbiosciences.com<br />

BD Diagnostics<br />

Stand: 080<br />

Germany<br />

Website: www.bd.com<br />

Bio-Rad Laboratories<br />

Stand: 090<br />

USA<br />

Website: www.bio-rad.com<br />

Bruker Daltonics<br />

Stand: 022<br />

Germany<br />

Website: www.bdal.de<br />

Caprotec Bioanalytics GmbH<br />

Stand: 044<br />

Germany<br />

Website: www.caprotec.com<br />

Digilab Genomic Solutions (UK) Ltd<br />

Stand: 023<br />

UK<br />

Website: www.genomicsolutions.com<br />

Dionex Corporation<br />

Stand: 061<br />

Switzerland<br />

Website: www.dionex.com<br />

Dualsystems Biotech AG<br />

Stand: 073<br />

Switzerland<br />

Website: www.dualsystems.com<br />

Eksigent Technologies<br />

Stand: 084<br />

USA<br />

Website: www.eksigent.com<br />

Elsevier<br />

Stand: 078<br />

The Netherlands<br />

Website: www.elsevier.com<br />

GENOMIC SOLUTIONS<br />

CovalX AG<br />

Stand: 083<br />

Switzerland<br />

Website: www.covalx.com<br />

CTMM<br />

The Netherlands<br />

Website: www.ctmm.nl<br />

Decodon<br />

Stand: 101<br />

Germany<br />

Website: www.decodon.com<br />

Denator AB<br />

Stand: 072<br />

Sweden<br />

Website: www.denator.com<br />

C OVAL X<br />

Solutions for Protein Complex Analysis<br />

EMBL-European Bioinformatics Institute<br />

Stand: 047<br />

UK<br />

Website: www.ebi.ac.uk<br />

Epitomics, Inc.<br />

Stand: 046<br />

USA<br />

Website: www.epitomics.com<br />

EuPA / The Swedish Academy of Pharmaceutical Sciences<br />

Stand: 074<br />

Website: www.eupa.org<br />

GE Healthcare Europe GmbH<br />

Stand: 052<br />

Germany<br />

Website: www.gelifesciences.com<br />

168 169


Genebio Geneva Bioinformatics<br />

Stand: 103<br />

Switzerland<br />

Website: www.genebio.com<br />

GenoLogics<br />

Stand: 100<br />

Canada<br />

Website: www.genologics.com<br />

GenWay Biotech, Inc.<br />

Stand: 012<br />

USA<br />

Website: www.genwaybio.com<br />

GL Sciences, Inc.<br />

Stand: 001<br />

Japan<br />

Website: www.gls.co.jp<br />

GenWay Biotech, Inc.<br />

Protein and Antibody Solutions<br />

Integrated Analysis, Inc.<br />

USA<br />

Website: www.i-a-inc.com<br />

Invitrogen / Dynal<br />

Stand: 108<br />

Scotland, UK<br />

Website: www.invitrogen.com<br />

IOS Press<br />

Stand: 105<br />

The Netherlands<br />

Website: www.iospress.nl<br />

JPT Peptide Technologies GmbH<br />

Stand: 003<br />

Germany<br />

Website: www.jpt.com<br />

Hoefer, Inc.<br />

Stand: 102<br />

USA<br />

Website: www.hoeferinc.com<br />

HUPO 2009<br />

Stand: 075<br />

Website: www.hupo2009.com<br />

HUPO 2010<br />

Australia<br />

Website: www.hupo2010.com<br />

Labcyte, Inc.<br />

Stand: 110<br />

USA<br />

Website: www.labcyte.com<br />

Ludesi AB<br />

Stand: 087<br />

Sweden<br />

Website: www.ludesi.com<br />

Merck & Co., Inc.<br />

USA<br />

Website: www.merck.com<br />

TM<br />

HUPO HQ<br />

Stand: 076<br />

Canada<br />

Website: www.hupo.org<br />

INTAVIS Bioanalytical Instruments<br />

Stand: 002<br />

Germany<br />

Website: www.intavis.com<br />

Merck/EMD, Novagen & Calbiochem<br />

Stand: 107<br />

USA<br />

Website: www.emdchemicals.com<br />

Miltenyi Biotec<br />

Stand: 030<br />

Germany<br />

Website: www.miltenyibiotec.com<br />

170 171


Nanoxis AB<br />

Stand: 051<br />

Sweden<br />

Website: www.nanoxis.com<br />

Netherlands Genomics Initiative / Netherlands Proteomics Centre<br />

Stand: 009<br />

The Netherlands<br />

Website: www.genomics.nl / www.netherlandsproteomicscentre.nl<br />

Nonlinear Dynamics<br />

Stand: 037<br />

UK<br />

Website: www.nonlinear.com<br />

Pall Life Sciences<br />

Stand: 011<br />

UK<br />

Website: www.pall.com<br />

Peaks<br />

Stand: 031<br />

Canada<br />

Website: www.bioinfor.com<br />

PSS Europe GmbH<br />

Stand: 045<br />

Germany<br />

Website: www.pss-europe.de<br />

Pressure BioSciences, Inc.<br />

Stand: 118<br />

USA<br />

Website: www.pressurebiosciences.com<br />

Proteored<br />

Spain<br />

Website: www.proteored.org<br />

Proxeon<br />

Stand: 004<br />

Denmark<br />

Website: www.proxeon.com<br />

Qiagen<br />

Stand: 071<br />

UK<br />

Website: www.qiagen.com<br />

RSC Publishing<br />

Stand: 111<br />

UK<br />

Website: www.rsc.org<br />

R&D Systems Europe Ltd<br />

Stand: 066<br />

UK<br />

Website: www.rndsystems.com<br />

Rosetta Bio<strong>software</strong><br />

Stand: 085<br />

USA<br />

Website: www.rosettabio.com<br />

Science International / AAAS<br />

Stand: 079<br />

UK<br />

Website: www.science-int.co.uk<br />

national institutefor proteomics<br />

Promega Corporation<br />

Stand: 042<br />

USA<br />

Website: www.promega.com<br />

Protein Forest, Inc.<br />

Stand: 086<br />

USA<br />

Website: www.proteinforest.com<br />

SERVA Electrophoresis GmbH / Bridge4Bio<br />

Stand: 068<br />

Germany<br />

Website: www.serva.de<br />

Shimadzu Europe GmbH<br />

Stand: 092<br />

Germany<br />

Website: www.shimadzu.eu<br />

172 173


Sigma-Aldrich<br />

Stand: 026<br />

USA<br />

Website: www.sigma-aldrich.com<br />

Silantes GmbH<br />

Stand: 005<br />

Germany<br />

Website: www.silantes.com<br />

Syngene<br />

Stand: 040<br />

UK<br />

Website: www.syngene.com<br />

Thermo Scientific<br />

Stand: 034<br />

UK<br />

Website: www.thermo.com<br />

UVic Genome BC Proteomics Centre<br />

Stand: 006<br />

Canada<br />

Website: www.proteincentre.com<br />

UVP<br />

Stand: 007<br />

UK<br />

Website: www.uvp.com<br />

Wiley-VCH Verlag<br />

Stand: 1<strong>19</strong><br />

Germany<br />

Website: www.wiley-vch.de<br />

Waters<br />

Stand: 060<br />

France<br />

Website: www.waters.com<br />

UVic Genome BC<br />

PROTEOMICS CENTRE<br />

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Applied Biosystems/MDS Analytical Technologies is the leading provider of reliable, high throughput solutions<br />

that best meet the needs of your entire targeted protein quantitation pipeline. From automating MRM assay<br />

development to reducing the cost of candidate verification by using a global internal standard, we pioneer systems<br />

and workflows that help you achieve more.<br />

See these industry-leading targeted quantitative proteomics solutions in booth #63.<br />

• 4000 QTRAP ® LC/MS/MS System —The only system to provide MRM quantitation<br />

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• MRMPilot Software—Automated MRM methods development and optimization<br />

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of biomarker candidates<br />

• MultiQuant Software—Easy-to-use <strong>software</strong> optimized for high throughput<br />

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• Scheduled MRM Algorithm—Maximizing MRM dwell times for more robust<br />

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Partner with Applied Biosystems/MDS Analytical Technologies.<br />

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BOOTH #63<br />

Applera, Applied Biosystems and AB (Design) are registered trademarks of Applera Corporation or its subsidiaries in the US and/or certain other countries. QTRAP is a registered trademark and mTRAQ, MRMPilot, Scheduled MRM<br />

and MultiQuant are trademarks of Applied Biosystems/MDS Analytical Technologies, a joint venture of Applera Corporation and MDS Inc. MDS Analytical Technologies is a trademark of MDS Inc.<br />

© 2008 Applera Corporation and MDS Inc. Joint Owners. All rights reserved.<br />

174 175


16<br />

7<br />

6 14<br />

8<br />

2<br />

5<br />

4<br />

11<br />

21<br />

<strong>19</strong><br />

10<br />

9<br />

18<br />

20<br />

23 3<br />

1<br />

22<br />

17<br />

12<br />

13<br />

15<br />

Hotel Map<br />

Nr. Hotel Nr. Hotel<br />

1 Hotel Okura Amsterdam 12 Mercure Amsterdam a/d Amstel<br />

2 NH Barbizon Palace 13 Holiday Inn<br />

3 Hilton Amsterdam 14 Park Plaza Victoria Amsterdam<br />

4 NH City Centre 15 Novotel Amsterdam<br />

5 NH Grand Hotel Krasnapolsky 16 Ibis Amsterdam Centre<br />

6 Crowne Plaza Amsterdam City Centre 17 Artemis Amsterdam<br />

7 Renaissance Amsterdam Hotel 18 Vondel Park Plaza<br />

8 Sofitel Amsterdam <strong>19</strong> Eden Hotel Amsterdam<br />

9 Park Hotel 20 Trianon Hotel<br />

10 Eden Rembrandt Square 21 Amstel Botel<br />

11 Mövenpick Hotel Amsterdam City 22 Hotel Casa 400<br />

23 Bilderberg Garden Hotel Amsterdam<br />

176

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