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Table of Contents<br />
word of welcome by the congress chairs 3<br />
word of welcome by the president 4<br />
acknowledgements 5<br />
Committees 6<br />
Awards 8<br />
congress related meetings 9<br />
Poster Viewing 9<br />
corporate Workshops 10<br />
Monday 18 <strong>August</strong> 10<br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong> 12<br />
Wednesday 20 <strong>August</strong> 14<br />
Floor plans Congress Venue <strong>19</strong><br />
List of Exhibitors 21<br />
ORAL PRESENTATIONS<br />
Program Saturday 16 <strong>August</strong> 23<br />
Program at a glance 23<br />
HUPO Educational Day 24<br />
HUPO Initiatives Program 24<br />
Program Sunday 17 <strong>August</strong> 31<br />
Program at a glance 31<br />
HUPO Clinical Day 32<br />
HUPO Initiatives Program 33<br />
Program Monday 18 <strong>August</strong> 35<br />
Program at a glance 35<br />
Plenary speakers 38<br />
Full program details 42<br />
1
Table of Contents<br />
Program <strong>Tuesday</strong> <strong>19</strong> <strong>August</strong> 47<br />
Program at a glance 47<br />
Plenary speakers 48<br />
Full program details 52<br />
Program Wednesday 20 <strong>August</strong> 59<br />
Program at a glance 59<br />
Plenary speakers 60<br />
Full program details 62<br />
poster topics 66<br />
Poster listing 68<br />
Monday 18 <strong>August</strong> 68<br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong> 98<br />
Wednesday 20 <strong>August</strong> 128<br />
Information for Oral and Poster Presenters 159<br />
Exhibition Information 160<br />
General Information 161<br />
Social Program 165<br />
Accompanying Persons Tour / excursion 166<br />
Exhibitor and sponsor listing 167<br />
Hotel Map 176<br />
Word of welcome by the<br />
congress chairs<br />
Dear Colleagues<br />
On behalf of the HUPO 2008 Amsterdam Congress Organizing Committee, HUPO and<br />
EuPA, we would like to extend our warm welcome to all of you attending the HUPO<br />
7th Annual World Congress held in the RAI Convention Centre in Amsterdam, The<br />
Netherlands. We like to thank you for your participation as presenter, exhibitor and/<br />
or attendee.<br />
The theme of the meeting is “Proteome Biology”. With this title the Organizing<br />
Committee wants to indicate that in spite of the amazing complexity of the proteome,<br />
the field of proteomics has matured to a degree where significant progress in biology<br />
and medicine can be realized by applying the powerful proteomic technologies. This<br />
expectation is based on rapid progress in the development of a range of technologies<br />
that increasingly contribute to the editing of comprehensive maps of the various cells’<br />
proteomes and move forward the boundaries of the “terra incognita”. The title of the<br />
meeting should also indicate the need for proteomics to progress beyond identifying the<br />
building blocks of the proteome towards understanding of how the complex biological<br />
functions of a cell are orchestrated via intricate networks of proteins interacting with<br />
themselves and other types of biomolecules.<br />
The meeting offers a full program with more than 140 lectures, 1200 posters,<br />
the Clinical Day and Educational sessions, the HUPO Initiatives progress meetings,<br />
corporate workshops, and a full exhibition with the latest technologies.<br />
Besides a challenging scientific program we also organised a very attractive social<br />
program! We hope that together with all of you we can create a scientifically creative and<br />
socially lively atmosphere at the meeting, whereby the presentations and discussions<br />
will contribute to further progress in the field of proteomics.<br />
Sincerely yours,<br />
Chairs of the HUPO 2008 meeting<br />
Albert Heck<br />
Utrecht University<br />
Netherlands Proteomics Centre<br />
Anne-Claude Gavin<br />
EMBL Heidelberg<br />
Ruedi Aebersold<br />
ETH Zurich and University of Zurich<br />
Institute for Systems Biology, Seattle<br />
2 3
Word of welcome by the<br />
President<br />
Dear Colleagues,<br />
On behalf of the Human Proteome Organisation I welcome you to the HUPO 7th Annual<br />
World Congress in Amsterdam.<br />
This year’s congress is entitled “Proteome Biology” and it emphasizes the need for<br />
proteomics to progress beyond identifying the building blocks of the proteome towards<br />
understanding of how the complex biological functions of a cell are orchestrated<br />
via intricate networks of proteins interacting with themselves and other types of<br />
biomolecules.<br />
Building on the success of HUPO’s past congresses, this collaborative effort between<br />
HUPO and EuPA to bring you once again “The can’t miss <strong>event</strong> of the year” in proteomics,<br />
has built a powerful scientific program led by visionaries in proteomics, and pioneers<br />
in education.<br />
Since proteomics depends heavily on the technologies that will drive this discipline<br />
forward, I am especially pleased and very thankful for the continued participation and<br />
the great support of all the congress exhibitors and sponsors.<br />
Thanks to all participants, many have traveled far away from home, the fascination<br />
with proteomics is represented by the great attendance of this congress, as we have<br />
experienced in past HUPO congresses that are attended by delegates from over 50<br />
different countries. I also extend my sincere greetings to all the funding agencies<br />
and their representatives who are helping shape and define proteomics, its goals and<br />
objectives and in particular are in full support of HUPO and its activities.<br />
Whether you are attending the congress to share information, to learn, to discover new<br />
technologies, to seek collaborations, to be involved, or to simply have the opportunity<br />
to network with scientists of similar interests, I trust that you will find that HUPO’s<br />
passion to the field of proteomics and its commitment to bring the best science to<br />
its congress will help you achieve your goal and will re-confirm that the HUPO Annual<br />
Congress is a must for you and your colleagues throughout the World.<br />
Enjoy your stay in the wonderful city of Amsterdam and hope to see you in Toronto<br />
next year for HUPO 8th Annual World Congress September 26-30, 2009.<br />
Acknowledgements<br />
MAIN sponsors<br />
Elite sponsor HUPO Scientific initiatives<br />
exhibitors<br />
Rolf Apweiler<br />
HUPO President<br />
The 7th HUPO Annual World Congress expresses its warm thanks to our Exhibitors<br />
for supporting the Congress. We encourage all Congress Delegates to visit the<br />
Exhibition and to learn more about the products and services. The Exhibition is located<br />
in Exhibition Hall 10. Please consult the Floor plan.<br />
The exhibitors contact details are listed on pages 167-174.<br />
4 5
Committees<br />
Congress Chairs<br />
Albert Heck<br />
The Netherlands Proteomics Centre<br />
Utrecht University, The Netherlands<br />
Anne-Claude Gavin<br />
EMBL Heidelberg, Germany<br />
Ruedi Aebersold<br />
ETH Zurich<br />
University of Zurich, Switzerland<br />
Institute for Systems Biology, Seattle, USA<br />
Endorsed by<br />
Human Proteome Organisation<br />
www.hupo.org<br />
Netherlands Proteomics Centre<br />
www.netherlandsproteomicscentre.nl<br />
Executive Organizing Committee<br />
Werner Most<br />
Netherlands Proteomics Centre<br />
Silvie Hermsen<br />
Netherlands Proteomics Centre<br />
Wehbeh Barghachie<br />
HUPO Director of Operations<br />
HUPO Executive Committee<br />
Rolf Apweiler<br />
President<br />
Catherine Fenselau<br />
Senior VP<br />
Young-Ki Paik<br />
VP<br />
John Bergeron<br />
Past President<br />
Richard Simpson<br />
Treasurer<br />
Peipei Ping<br />
Secretary General<br />
Mathias Uhlén<br />
Member at Large<br />
European Proteomics Association<br />
www.eupa.org<br />
Congress Secretariat<br />
International Conference Services BV<br />
P.O. Box 14645<br />
1001 LC Amsterdam<br />
The Netherlands<br />
Tel: +31 (0)20 679 32 18<br />
Fax: +31 (0)20 675 82 36<br />
Email: hupo2008@ics-online.nl<br />
www.hupo2008.com<br />
Session Chairs & Pre-Congress Organisers<br />
The Congress Organization wishes to thank all those who have been actively involved<br />
in the organization of the Scientific Program as pre-congress program organizer or<br />
session chair. Their involvement is highly appreciated and has greatly contributed to<br />
the quality of the final program.<br />
6 7
Awards<br />
HUPO Discovery in Proteomic Sciences award:<br />
Catherine Costello<br />
HUPO Distinguished Service Award:<br />
Richard Simpson<br />
HUPO Distinguished Achievement Award in Proteomic Sciences:<br />
This Award is Sponsored by Journal of Proteome Research & ACS<br />
Denis Hochstrasser and Matthias Mann<br />
HUPO Young Investigator Awards:<br />
Jesper Olsen<br />
Shabaz Mohammed<br />
Adriana Paes Leme<br />
EuPA Senior Scientist Award in Proteomic Sciences:<br />
Stellan Hjerten<br />
EuPA Ph.D. Award Nominees:<br />
Bernd Bodenmiller<br />
Simone Lemeer<br />
Anissa Sidibe<br />
Tine E. Thingholm<br />
Leonie Waanders<br />
We thank the 2008 sponsors of student travel awards:<br />
Genome Canada Travel Awards to Canadian Students<br />
Hoffmann – La Roche AG Travel Awards<br />
Congress Related Meetings<br />
(on invitation only)<br />
HUPO Industry Advisory Board Meeting<br />
Sunday 17 <strong>August</strong><br />
Room L - 09.00 - 12.00 hrs<br />
Education Committee Meeting<br />
Sunday 17 <strong>August</strong><br />
Room P - 09.00 - 11.00 hrs<br />
HUPO Council Meeting<br />
Sunday 17 <strong>August</strong><br />
Room CD - 13.30 - 18.00 hrs<br />
Press Conference<br />
Monday 18 <strong>August</strong><br />
Room H - 12.30 - 14.00 hrs<br />
Regional HUPO Presidents’ Breakfast Meeting<br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />
Room P - 07.00 - 07.55 hrs<br />
Editorial Board meeting “Journal of Proteomics” (Elsevier)<br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />
Café Amsterdam - 12.30 - 14.00 hrs<br />
US HUPO Board Meeting<br />
Wednesday 20 <strong>August</strong><br />
Room P - 12.00 - 13.30 hrs<br />
Poster Viewing<br />
Posters will be on display in the exhibition and poster area (Hall 10 of the RAI Convention<br />
Centre). Each day posters can be viewed during meeting breaks which are scheduled<br />
daily on the following hours:<br />
Morning break<br />
Lunch break<br />
Afternoon break<br />
09.30 - 11.00 hrs<br />
12.30 - 14.00 hrs<br />
15.30 - 16.00 hrs<br />
We would like to ask all poster presenters to be present at their poster at least<br />
during the morning and afternoon break. All posters will be on display for one day only,<br />
either on Monday, <strong>Tuesday</strong> or Wednesday. Posters will be numbered as P-MON-#,<br />
P-TUE-# and P-WED-# respectively (see pages 68 – 157).<br />
8 9
Corporate Workshops<br />
QIAGEN<br />
07.00 - 07.50 hrs, room CD<br />
Tickets to be collected at booth 71<br />
Protein and peptide analysis from clinical specimens<br />
Kerstin Steinert, Director R & D, QIAGEN GmbH, Hilden, Germany<br />
Udo Roth, R & D Scientist, QIAGEN GmbH, Hilden, Germany<br />
Direct analysis of peptides in body fluids<br />
Hepcidin is the key regulator of iron metabolism and its concentration in urine provides<br />
diagnostic value in diseases. We present a new technique overcoming current hepcidin<br />
quantification issues by MALDI-MS in combination with sample preparation on-chip.<br />
Hepcidin detected directly in crude urine enables the establishment of HTP quantification<br />
workflows of this peptide.<br />
Standardized sample preparation from different tissues<br />
Huge numbers of Formalin-Fixed Paraffin-Embedded (FFPE) are prepared per year.<br />
Previously, due to the crosslinks formed during the fixation process, their analysis<br />
was limited to histochemical techniques. Here we present a method enabling efficient<br />
extraction of full-length proteins suitable for analysis of specific protein targets or<br />
proteomic approaches.<br />
PROMEGA CORPORATION<br />
07.00 - 07.50 hrs, room EF<br />
Tickets to be collected at booth 42<br />
breakfast workshops<br />
ProteasMAX Surfactant<br />
Improve Overall Confidence in Protein Identification<br />
Incomplete solubilization, digestion and poor peptide recovery are limitations in protein<br />
sample preparation for MS analysis. ProteasMAX Surfactant reduces these<br />
limitations while avoiding negative effects observed with common solubilizing agents.<br />
In-gel digestion showed up to 1.8-fold increase in protein coverage and up to 6.9-fold<br />
increase in MASCOT score.<br />
Monday, 18 <strong>August</strong><br />
AGILENT TECHNOLOGIES<br />
12.30 - 14.00 hrs, room B<br />
Tickets to be collected at booth 32<br />
Agilent’s HPLC-Chip/LC-MS:<br />
A key enabling technology for integrated proteomics workflows<br />
HPLC-Chip/LC-MS sits at the center of an integrated proteomics workflow from<br />
sample preparation to data analysis, encompassing identification and characterization,<br />
biomarker discovery and quantitation. We discuss the new HPLC-Chip 6530 Accurate<br />
Mass Q-TOF for more confident protein identification and the HPLC-Chip / 6460 Triple<br />
Quadrupole for sensitive targeted peptide quantitation. Leading scientists will present<br />
applications using the innovative HPLC-Chip/MS technology.<br />
APPLIED BIOSYSTEMS /<br />
MDS ANALYTICAL TECHNOLOGIES<br />
12.30 - 14.00 hrs, room CD<br />
Tickets to be collected at booth 63<br />
Increasing Throughput and Quality of Results in Protein Biomarker Discovery<br />
and Verification<br />
Increasing throughput can often mean compromising the quality of data and results.<br />
Innovations from Applied Biosystems/MDS Analytical Technologies break this paradigm<br />
and actually increase the quality of results along with increasing sample throughput.<br />
This workshop will discuss how advances in MS systems, <strong>software</strong>, reagents and<br />
workflows enable new levels of protein biomarker productivity.<br />
BRUKER DALTONICS<br />
12.30 - 14.00 hrs, room EF<br />
Tickets to be collected at booth 22<br />
lunch workshops<br />
(R)evolution in Label-free Proteomics and Data Evaluation<br />
A prestigious researchers’ panel will present talks detailing a series of innovative applications<br />
utilizing the maXis for protein identification and quantitation with accurate<br />
mass, ultra high resolution across a broad mass range, high sensitivity, all at the high<br />
speed needed to take full advantage of ultra-high performance liquid chromatography.<br />
10 11
Corporate Workshops<br />
ROSETTA BIOSOFTWARE<br />
07.00 - 07.50 hrs, room B<br />
Tickets to be collected at booth 85<br />
Real-World Proteomics:<br />
A Spectrum of Workflows in the Rosetta Elucidator System<br />
Presented by Tim Bonnert, Ph.D. Rosetta Bio<strong>software</strong> & Hendrik Neubert, Ph.D.<br />
Pfizer Global Research and Development<br />
The diversity of scientific questions that are being addressed by LC/MS proteomics<br />
necessitates a varied approach to experimental design and execution. Data could be<br />
generated on multiple high- or low-resolution instruments as label-free or labelled (e.g.<br />
SILAC, or ICAT) samples using 1D- or multidimensional separation in data dependent,<br />
data independent (MS(E)) or targeted MS/MS modes. Such diverse methods of<br />
data generation may also benefit from multiple database search engines and diverse<br />
statistical, analytical, and visualisation methods.<br />
The Rosetta Elucidator® system (www.rosettabio.com/elucidator) provides a<br />
comprehensive solution for the rapid and efficient analysis of any number of samples<br />
collected by any of these workflows. This seminar will showcase a number of different<br />
LC/MS workflows and will also discuss how LC/MALDI offers several benefits over the<br />
more conventional LC/ESI methodology (see Neubert et al. J Proteome Res. 2008, 7,<br />
pp2270-9)<br />
GE HEALTHCARE EUROPE<br />
07.00 - 07.50 hrs, room CD<br />
Tickets to be collected at booth 52<br />
breakfast workshops<br />
Quantitative solutions in proteomics:<br />
A novel use of Ettan DIGE fluorescent cye dyes and 2D LC<br />
This GE Healthcare seminar will introduce an exciting and new technique, combining a<br />
novel dual labelling strategy with 2D LC. Samples are labeled at the protein level with<br />
both Ettan DIGE fluorescent cye dyes and stable isotope labels (ICPL), prior to 2D LC.<br />
Quantitation is performed at both the protein and peptide level. This method addresses<br />
important issues such as loading capacity, dynamic range, sample complexity and<br />
relating peptide signals to parent protein origin.<br />
<strong>Tuesday</strong>, <strong>19</strong> <strong>August</strong><br />
THERMO SCIENTIFIC<br />
12.30 - 14.00 hrs, room B<br />
Tickets to be collected at booth 34<br />
Thermo Fisher Scientific cordially invites you to attend an educational workshop on the<br />
latest integrated solutions for protein characterization and quantitation featuring the<br />
following two talks:<br />
Driving Biological Discovery using the LTQ Orbitrap<br />
John Yates, Ph.D. - The Scripps Research Institute - Department of Cell Biology<br />
First Impressions of the MALDI LTQ Orbitrap<br />
Michael Karas, Ph.D.<br />
Institute for Pharmaceutical Chemistry - Goethe University, Frankfurt am Main<br />
DIONEX CORPORATION<br />
12.30 - 14.00 hrs, room CD<br />
Tickets to be collected at booth 61<br />
Approaches for High Resolution 2-D LC/MS in Proteomics<br />
Multidimensional liquid chromatography provides high resolution identification of<br />
proteins by MS/MS; including scarce and difficult to separate proteins, and is gaining<br />
popularity over traditional 2-D electrophoresis. Dionex recently introduced a new<br />
proteomics MDLC platform. This workshop will review automation and optimization of<br />
MDLC methods for top-down and bottom-up protein identification.<br />
BRUKER DALTONICS<br />
12.30 - 14.00 hrs, room EF<br />
Tickets to be collected at booth 22<br />
(R)evolution in Top Down Analysis and PTM Discovery<br />
Presented will be an overview of recent proteomics application:<br />
MALDI-TDS for novel Top-Down Sequencing providing 100% protein sequence<br />
coverage incl. C- / N- terminal assignments,<br />
ETD/PTR for PTM and intact protein analysis in the HCTultra ion trap<br />
high performance MALDI tissue imaging using the SmartBeam proprietary laser<br />
PROMEGA CORPORATION<br />
12.30 - 14.00 hrs, room P<br />
Tickets to be collected at booth 42<br />
lunch workshops<br />
HaloLink Protein Arrays for Functional Proteomics<br />
Promega’s HaloLink protein arrays allow rapid creation of arrays on demand. HaloTag®<br />
fusion bait proteins expressed in vitro or in vivo are covalently bound to a glass slide<br />
through our proprietary HaloTag® linkage. Bait proteins can be captured directly from<br />
lysate or reaction mix without prior purification, leading to rapid, parallel and multiplex<br />
analysis of protein interactions.<br />
12 13
Corporate Workshops<br />
ROSETTA BIOSOFTWARE<br />
07.00 - 07.50 hrs, room B<br />
Tickets to be collected at booth 85<br />
The Analysis of Diagnostic Markers For Lysosomal Storage Disorders:<br />
A Case Study in Label-Free Differential Analysis in the Rosetta Elucidator System<br />
Presented by Cindy Chepanoske, Ph.D. Rosetta Bio<strong>software</strong><br />
The Rosetta Elucidator® system (www.rosettabio.com/elucidator) provides a<br />
comprehensive solution for the rapid and efficient analysis of LC/MS data from multiple<br />
instruments and workflows. Multi-instrument support by the Elucidator system has<br />
been further expanded by the integration of Waters® Ultra Performance LC/MS(E)®<br />
proteomics discovery data and results from the Identity(E) search engine, so that data<br />
produced on Waters’ instrumentation can be analyzed using the Elucidator <strong>software</strong>.<br />
Gaucher disease is the most common lysosomal storage disease and there is great<br />
clinical interest to identify and quantify additional biomarkers for this disease. A labelfree<br />
LC/MS(E) serum profiling analysis was conducted to quantitatively characterize<br />
candidate biomarkers. The workflow used for biomarker discovery in the Elucidator<br />
system will be presented, followed by a live demonstration of the <strong>software</strong>.<br />
GE HEALTHCARE EUROPE<br />
07.00 - 07.50 hrs, room CD<br />
Tickets to be collected at booth 52<br />
Biacore analysis – exploring the real-time world of protein interactions<br />
Speaker: Erik Verschuuren<br />
breakfast workshops<br />
Biacore systems for label-free interaction analysis provide information on binding<br />
specificities, affinities and kinetics, as well as interactant concentrations. This<br />
presentation will exemplify how Biacore systems are used to validate, quantify,<br />
and characterize protein interactions to unravel the mechanisms behind cellular<br />
processes.<br />
Wednesday, 20 <strong>August</strong><br />
THERMO SCIENTIFIC<br />
07.00 - 07.50 hrs, room EF<br />
Tickets to be collected at booth 34<br />
Thermo Fisher Scientific cordially invites you to attend an educational workshop on the<br />
latest integrated solutions for protein characterization and quantitation featuring the<br />
following two talks:<br />
Approaches to global phosphoproteomic analysis<br />
Nick Morrice, Ph.D.<br />
MRC Protein Phosphorylation Unit<br />
University of Dundee<br />
Absolute quantification of targeted endogenous salivary peptides using heavy<br />
isotope-labeled synthetic internal standards and high resolution selected reaction<br />
monitoring mass spectrometry<br />
Markus Hardt, Ph.D.<br />
University of California, San Francisco<br />
Department of Cell and Tissue Biology<br />
WATERS<br />
12.30 - 14.00 hrs, room B<br />
Tickets to be collected at booth 60<br />
The next generation of proteomics technology;<br />
Combining novel nanoscale separations with high-performance mass spectrometry<br />
This seminar will focus on new separation and mass spectrometry techniques that can<br />
be applied to proteomics research. We will detail the development and application of<br />
the TRIZAIC® nanoACQUITY UPLC proteomics system, and the Xevo TQ MS, a novel<br />
tandem quadrupole LC-MRM system.<br />
BIO-RAD LABORATORIES<br />
12.30 - 14.00 hrs, room CD<br />
Tickets to be collected at booth 90<br />
Technologies for Biomarker Discovery<br />
lunch workshops<br />
With the right technologies, the challenges of Biomarker discovery can be minimized.<br />
ProteoMiner technology reduces sample complexity, allowing you to dig deeper in the<br />
proteome. 2-DGE and SELDI enable the detection of changes in protein levels and<br />
potential biomarker candidates. Data generated with these technologies demonstrates<br />
their power for Biomarker discovery.<br />
14 15
INVITROGEN<br />
12.30 - 14.00 hrs, room EF<br />
Tickets to be collected at booth 108<br />
Discovery of SLE Autoantibody Biomarkers using Protein Microarray Technology &<br />
Protein Sample Purification and Fractionation using Dynabeads Magnetic beads<br />
The diagnostic value of serum autoantibodies for many diseases, including cancer,<br />
diabetes, and autoimmune disorders is well established. Realizing the promise of<br />
autoantibody panels in diagnosis, prognosis and treatment response predictions will<br />
require the use of multiplex tools that enable investigators to query the autoantibody<br />
profile on a proteomic scale. Identifying the antigens that elicit an autoimmune<br />
response can yield panels of biomarkers that can be used as classifiers for particular<br />
diseases, disease stages, or as predictors of patient outcomes. The present study<br />
utilized high content functional protein microarrays comprised of >8,000 purified fulllength<br />
human proteins, including a panel of >20 annotated autoantigens. These protein<br />
microarrays were probed with serum from Systemic Lupus Erythematosus (SLE)<br />
patients and compared with serum from disease-free donors. Patient serum from<br />
other autoimmune disorders (RA, vasculitis) were included to identify SLE-specific<br />
markers rather than autoimmune-specific. Statistical algorithms were developed to<br />
analyze data from individual microarrays and to compare data between populations. This<br />
line of investigation identified a panel of 18 novel biomarkers which could differentiate<br />
SLE patients from healthy individuals more accurately than a panel of 10 established<br />
SLE biomarkers. Validation studies utilizing the Luminex platform were used to confirm<br />
the results obtained via the ProtoArray. Taken together, our results suggest that<br />
functional protein microarray technology is a powerful new tool for the rapid discovery<br />
of autoantigen biomarkers.<br />
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1<br />
1 2 1<br />
3 2 2<br />
4 3 3<br />
5 4 4<br />
6 5 5<br />
7 6<br />
8 7<br />
8<br />
9<br />
9<br />
WHO & WHERE?<br />
Node 4 Associate<br />
F.J. Blanco - H J.Canalejo<br />
Node 4<br />
X. Bustelo - CIC<br />
*<br />
Node 2<br />
J. Mato - CIC-bioGUNE<br />
F. Corrales - CIMA<br />
JM. Arizmendi - UPV<br />
Node 3<br />
J. Abián - LP-CSIC/UAB<br />
J. Arribas - HUVH<br />
S. Martínez - PCB<br />
D. Andreu - UPF<br />
FX. Avilés - IBB UAB<br />
O. Bachs - UB<br />
Central Structure<br />
JP. Albar - CNB<br />
JM. Mato - CIC-bioGUNE<br />
J. Abian - LP-CSIC/UAB<br />
*<br />
Overall Floor Plan Congress Venue<br />
Node 1<br />
JP. Albar - CNB<br />
C. Gil - PCM-UCM<br />
A. Marina - CBMSO<br />
I. Casal - CNIO<br />
J.M. Carazo - INB-CNB<br />
-<br />
Node 5 Associate<br />
P. Carrasco - UV<br />
Node 5<br />
M. S. del Pino - CIPF<br />
R. Bru - UA<br />
Room B<br />
HOW?<br />
Node 1 Associate<br />
V. Ceña - UCLM<br />
Node 6<br />
JA. Bárcena - UCO<br />
Current Working Groups:<br />
WG 1. Technological development and<br />
standardization of protocols.<br />
WG 2. Samples collection and handling.<br />
WG 3. Bioinformatics support.<br />
WG 4. Functional organization of proteomic<br />
services and coordination of price scales.<br />
WG 5. Training, education and diffusion.<br />
WG 6. Internationalization and coordination<br />
with other proteomic consortia<br />
and platforms.<br />
WG 7. Biomedical Proteomics.<br />
XXXX<br />
Auditorium<br />
Room Auditorium<br />
Room C-D<br />
Room E-F<br />
www.proteored.org<br />
WHY?<br />
ProteoRed purpose is the coordination and integration of activities of the<br />
proteomics facilities to guarantee the access of the scientific comunity to<br />
the state-of-the-art proteomics technology.<br />
WHEN?<br />
ProteoRed is continously improving standards on its proteomics services,<br />
by incorporating HUPO-PSI guidelines and formats, since June 2005, setting<br />
a quality label for their users.<br />
WHAT?<br />
- Protein and Peptide Molecular Weight Analysis<br />
- Protein Identification<br />
- Characterization and Protein Modifications<br />
- Differential Proteomics<br />
- Sequencing<br />
- Peptide Synthesis<br />
- 2D electrophoresis<br />
- Bioinformatics Tools<br />
TOOLS<br />
MIAPEs Web templates:<br />
GE, GI, MS, MSI<br />
PRIDE schema tools:<br />
PIKE, Virtual 2D, PRIDE<br />
viewer, GARBAN, …<br />
spanish institute for proteomics .<br />
Room A<br />
Room Auditorium<br />
Room Forum Room L<br />
Forum<br />
i<br />
E E N N T E T R N R A T A N R N C A C E N E C E T O T O S T S E O E S S E I S O I S O N I N O R N O R O O M MS O S MS<br />
HALL 10<br />
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- 116<br />
Speaker Ready Room<br />
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posters 001<br />
posters posters 001<br />
- 060<br />
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Waters<br />
52 Waters Waters<br />
52 52 I n t e r n e t<br />
I n t e r n e t<br />
C orner<br />
orner C orner<br />
Room N-N1-O1-O<br />
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C a t e r i n g a r e a<br />
a C t a e t r e i r n i g n g a r a e r a e a<br />
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posters posters 217 - 217 234 - 234<br />
1<strong>19</strong> 1<strong>19</strong> 118 118 115 115<br />
EE EE EE EE EE EE<br />
EXHIBITOR SERVICES<br />
EXHIBITOR SERVICES<br />
18 <strong>19</strong>
Floor Plan Exhibition Area<br />
List of Exhibitors<br />
Booth<br />
No.<br />
Organisation<br />
Booth<br />
No.<br />
Organisation<br />
EE<br />
EE<br />
HALL 10<br />
10<br />
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Waters<br />
I n I t n e t r e n r e n t<br />
e t<br />
C orner<br />
C orner<br />
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posters 117 - 166<br />
posters 117 - 166<br />
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posters posters 061 061 - 116<br />
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posters posters 167 167 - 216<br />
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posters posters 001 001 - 060<br />
- 060<br />
E N E T N R T A R N A C N E<br />
C E<br />
T O T O S E S S E S I S O I N O R N O R R O MS O M O MSS<br />
M S<br />
C C a t a e t r e i r n i g n g a r a e r a<br />
e a<br />
posters posters 305 305 - 374<br />
- 374<br />
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posters posters 217 217 - 234<br />
- 234<br />
1<strong>19</strong><br />
1<strong>19</strong><br />
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EXHIBITOR SERVICES<br />
001 GL Sciences Inc.<br />
002 INTAVIS Bioanalytical Instruments<br />
003 JPT Peptide Technologies GmbH<br />
004 Proxeon<br />
005 Silantes GmbH<br />
006<br />
UVic Genome BC Proteomics<br />
Centre<br />
007 UVP<br />
008<br />
Australian Proteome Analysis<br />
Facility Ltd<br />
009<br />
Netherlands Genomics Initiative /<br />
Netherlands Proteomics Centre<br />
011 Pall Life Sciences<br />
012 GenWay Biotech, Inc.<br />
022 Bruker Daltonics<br />
023 Digilab Genomic Solutions (UK) Ltd<br />
025 Atlas Antibodies<br />
026 Sigma-Aldrich<br />
027 American Chemical Society<br />
030 Miltenyi Biotec<br />
031 Peaks<br />
032 Agilent Technologies<br />
034 Thermo Scientific<br />
037 Nonlinear Dynamics<br />
040 Syngene<br />
042 Promega Corporation<br />
044 Caprotec Bioanalytics GmbH<br />
045 PSS Europe GmbH<br />
046 Epitomics, Inc.<br />
047<br />
EMBL-European Bioinformatics<br />
Institute<br />
051 Nanoxis AB<br />
052 GE Healthcare Europe GmbH<br />
060 Waters<br />
061 Dionex Corporation<br />
063<br />
Applied Biosystems / MDS<br />
Analytical Technologies<br />
066 R & D Systems Europe<br />
068 SERVA Electrophoresis GmbH<br />
070 Abfrontier Co. Ltd<br />
071 Qiagen<br />
072 Denator AB<br />
073 Dualsystems Biotech AG<br />
074<br />
EuPA / The Swedish Academy of<br />
Pharmaceutical Sciences<br />
075 HUPO 2009<br />
076 HUPO HQ<br />
078 Elsevier<br />
079 Science International / AAAS<br />
080 BD Diagnostics<br />
082 BD Biosciences<br />
083 CovalX AG<br />
084 Eksigent Technologies<br />
085 Rosetta Bio<strong>software</strong><br />
086 Protein Forest Inc<br />
087 Ludesi AB<br />
090 Bio-Rad Laboratories<br />
092 Shimadzu<br />
100 GenoLogics<br />
101 Decodon<br />
102 Hoefer, Inc<br />
103 Genebio Geneva Bioinformatics<br />
104 Axela Inc.<br />
105 IOS Press<br />
107<br />
Merck / EMD,<br />
Novagen & Calbiochem<br />
108 Invitrogen / Dynal<br />
110 Labcyte Inc.<br />
111 RSC Publishing<br />
115 Aushon BioSystems<br />
118 Pressure BioSciences, Inc.<br />
1<strong>19</strong> Wiley-VCH Verlag<br />
20 21
ty Number 207890<br />
ISSN 1742-206X<br />
11/07/2007 09:34:16<br />
es<br />
tions by<br />
cement<br />
eir<br />
the<br />
Paris,<br />
Image reproduced by permission of A. Manz, Lab Chip 2006, 6(4)<br />
t more<br />
erprize<br />
Research at the interface between<br />
chemistry, the –omic sciences and<br />
systems biology<br />
14020750<br />
Volume 3 | Number 8 | 2007 Molecular BioSystems Pages 509–568<br />
Molecular<br />
BioSystems<br />
www.molecularbiosystems.org Volume 3 | Number 8 | <strong>August</strong> 2007 | Pages 509–568<br />
HIGHLIGHT<br />
Diane M. Ramos and Antónia Monteiro<br />
Transgenic approaches to study<br />
wing color pattern development in<br />
Lepidoptera<br />
METHOD<br />
K. Imai, Y. Ogai, D. Nishizawa, S. Kasai,<br />
K. Ikeda and H. Koga,<br />
A novel SNP detection technique<br />
utilizing a multiple primer extension<br />
(MPEX) on a phospholipid polymercoated<br />
surface<br />
Indexed in<br />
MEDLINE!<br />
1742-206X(2007)3:8;1-8<br />
• Impact factor 4.121*<br />
• Fast publication times (average 80 days from receipt)<br />
• Enhanced HTML articles, including:<br />
– Hyperlinked compound information, including<br />
downloadable structures in text<br />
– Gene, Sequence and Cell Ontology terms linked to<br />
definitions and related articles<br />
– IUPAC Gold Book terms linked<br />
*2007 Thomson Scientific (ISI) Journal Citation Reports ®<br />
www.molecularbiosystems.org<br />
Registered Charity Number 207890<br />
08080727a<br />
Saturday 16 <strong>August</strong> 2008<br />
location <br />
Exhibition hall 10 Room Forum Room A Room B Room CD Room EF<br />
time <br />
whole day Exhibition build-up Educational Day<br />
HUPO<br />
Human Proteome<br />
Project I<br />
09.30 - 12.30<br />
Educational Day<br />
Session I<br />
09.30 - 12.00<br />
HUPO<br />
Human Antibody Initiative<br />
HUPO<br />
Liver Proteome<br />
Project<br />
HUPO<br />
Brain Proteome Project<br />
HUPO<br />
Proteome Biology of Stem<br />
Cells Initiative<br />
14.00 - 17.30<br />
Educational Day<br />
Session II<br />
14.30 - 17.00<br />
Model Organisms<br />
Workshop<br />
HUPO Human<br />
Kidney and Urine<br />
Proteome Project<br />
HUPO<br />
Human Proteome<br />
Project II<br />
18.30 - 21.00<br />
Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />
= Initiative = Other meeting<br />
22 23
Saturday 16 <strong>August</strong><br />
hupo educational day<br />
09.30 - 12.30 Educational Day Session i room: Forum<br />
Welcome Address<br />
Angelika Görg and Ole Jensen<br />
Gel-based Proteomics<br />
Angelika Görg<br />
Sample Preparation and Protein Detection Thierry Rabilloud<br />
Shot gun Proteomics<br />
Mike MacCoss<br />
Antibodies<br />
Mathias Uhlén<br />
14.00 - 17.30 Educational Day Session II<br />
Welcome Address<br />
Angelika Görg and Ole Jensen<br />
hupo initiatives program<br />
HUPO Human Proteome Project I Workshop<br />
room: A<br />
09.30 - 12.00<br />
Chairs: John Bergeron and Mathias Uhlén<br />
Introduction<br />
John Bergeron<br />
The Human Proteome; where are we now Matthias Mann<br />
One gene -<br />
Ruedi Aebersold<br />
one (or sufficient) proteotypic peptide(s)<br />
One gene – one antibody<br />
Mathias Uhlén<br />
Speed and Dynamic Range;<br />
John Yates<br />
bottle necks in mass spectrometry<br />
Post-translational modifications and Albert Heck<br />
protein processing<br />
and Alan Sawyer, Fredrick Ponten, Jack Greenblatt, Rolf Apweiler, Marty McIntosh,<br />
Tommy Nilsson, Young-Ki Paik, Giulio Superti-Furga and Anne-Claude Gavin.<br />
Mass Spectrometry<br />
Mass Spectrometry based Quantification<br />
Post-translational Modifications<br />
Roman Zubarev<br />
Shabaz Mohammed<br />
Ole Jensen<br />
Mass Spectrometry related Bioinformatics<br />
Session I;<br />
Comparison of search engines<br />
Bas van Breukelen<br />
Session II;<br />
Pierre-Alain Binz<br />
Standards for data-sharing and available resources and databases for metaannotation<br />
of proteomics<br />
24 25
HUPO Proteome Biology of Stem Cells Initiative Workshop<br />
14.30 - 17.00<br />
Chairs: Jeroen Krijgsveld and Albert Heck<br />
room: A<br />
14.30 The HUPO PBSCI: Where are we now<br />
Jeroen Krijgsveld, Utrecht University, The Netherlands<br />
14.40 Quantitative proteomics of embryonic stem cell differentiation<br />
Tony Whetton, University of Manchester, Manchester, UK<br />
14.55 Phosphorylation dynamics during differentiation of embryonic stem cells<br />
Javier Muñoz, Utrecht University, The Netherlands<br />
15.10 In-depth quantitation of the mouse ES cell proteome<br />
15.25<br />
Nina Hubner, Max Planck Institute for Biochemistry, Martinsried, Germany<br />
Quantification of early signaling <strong>event</strong>s in embryonic stem cell self-renewal<br />
Jarrod Marto, Harvard Medical School, Boston, USA<br />
15.40 Comparative proteome an transcriptome analysis of human, mouse<br />
and monkey ESCs during differentiation<br />
Ghasem Hosseini Salekdeh, Royan Institute, Tehran, Iran<br />
15.55<br />
16.15<br />
Break<br />
Discussion<br />
HUPO Brain Proteome Project Workshop<br />
14.30 - 17.00<br />
Chairs: Helmut E. Meyer, Michael Hamacher & Young Mok Park<br />
room: B<br />
In this workshop, colleagues will present new, innovative analysis strategies for study<br />
pathomechanisms of different neurodegenerative diseases.<br />
14.30 Welcome address & Update: Barbados Wish List<br />
Helmut E. Meyer & Michael Hamacher (MPC, GER)<br />
14.50 Proteinbiochips<br />
Helmut E. Meyer (MPC, GER)<br />
15.30 The balancer concept<br />
Joachim Klose (Charité, GER)<br />
16.00 Neuropathology<br />
Lea Grinberg (Sao Paolo, BR)<br />
16.30 Oral from Poster Session<br />
N.N. (N.N., N.N)<br />
16.50 General Discussion & End of Session<br />
Young Mok Park (KBSI, KOR) & All<br />
HUPO Liver Proteome Project Workshop<br />
room: CD<br />
14.30 - 17.00<br />
Chair: Laura Beretta<br />
Co-chairs and session leaders: John Bergeron, Young-Ki Paik, Chantal Housset,<br />
Xiaohong Qian<br />
Participants: Rolf Apweiler, Pengyuan Yang, Siqi Liu, Gil Omenn, Eric Deutsch,<br />
Lennart Martens, Paul Boersema, Ying Jiang<br />
Introduction<br />
The Human Proteome Project: The Liver Perspective<br />
mass spectrometry - based coverage / where are we now<br />
antibody - based coverage / resources, integration, complementarity<br />
localization, abundance and liver tissue specificity<br />
pilot projects<br />
towards a mouse proteome project<br />
Comparative Analysis Of The Liver And Plasma Proteomes<br />
proteins and glycoproteins<br />
peptides<br />
abundance<br />
Opportunities For The Study Of Liver Diseases Within Hlpp<br />
data repository<br />
liver disease biomarkers: a focus on liver cancer<br />
biobanks and mouse models<br />
5th HUPO Human Antibody Initiative Workshop R<br />
14.30 - 17.00<br />
Chair: Mathias Uhlén<br />
Welcome and introduction<br />
Snyder, Hudson, Uhlén<br />
Short update on the Human Protein Atlas Ponten, UU, Sweden<br />
Update on antibodies<br />
A. Mono-specific antibodies Hober, KTH, Sweden<br />
B. Monoclonal antibodies Sawyer, Monash, Australia<br />
Update on recombinant affinity reagents<br />
A. Introduction Hudson, Australia<br />
B. New strategies for selection Weiner, USA<br />
C. Array strategies for selection Borrebeack, Sweden<br />
Pilot projects for antibody generation<br />
A. Cancer related proteins Rodriguez, NCI, US<br />
B. SH2 domains Graslund, KI, Sweden<br />
C. Chromosome 21 genes Berglund, KTH, Sweden<br />
D. ProteomeBinder Taussig, Cambridge, England<br />
Antibodypedia - portal for validated antibodies<br />
A. Update of portal Bjorling, KTH, Sweden<br />
B. Standards for affinity reagents Hermjacob, EBI, England<br />
Discussions<br />
Snyder, Hudson and Uhlén<br />
A. Pilot projects and antibodypedia<br />
B. How to relate to a Human Proteome Project<br />
room: EF<br />
26 27
HUPO Human Proteome Project II Workshop<br />
18.30 - 21.00<br />
Chair: Rolf Apweiler<br />
Invitees: Funding agencies and Proteomics leaders<br />
Program to be announced<br />
HUPO Human Kidney and Urine Proteome Project<br />
18.30 - 21.00<br />
Session chair: Tadashi Yamamoto, Niigata University, Japan<br />
18.30 - 18.35<br />
Introduction<br />
Tadashi Yamamoto<br />
Chair of HKUPP, Niigata University, Japan<br />
room: A<br />
room: B<br />
18.35 - 20.20 Session 1<br />
Standards and Guidelines for Proteome Analysis of Non-Proteinuric Urine<br />
Co-chairs: Tadashi Yamamoto (Niigata University, Japan) and Antonia Vlahou<br />
(Biomedical Research Foundation of the Academy of Athens, Greece)<br />
18.35 - <strong>19</strong>.20 Summary of previous studies and discussion<br />
Visith Thongboonkerd<br />
Medical Molecular Biology Unit, Office of Research and Development, Faculty of Medicine,<br />
Siriraj Hospital, Mahidol University, Bangkok, Thailand<br />
<strong>19</strong>.20 - <strong>19</strong>.32 Different urine desalting methods and their impact on 2D<br />
gel electrophoresis quality and protein identification<br />
Hassan Dihazi<br />
Clinical Proteomics Laboratories, Nephrology and Rheumatology, Georg-<strong>August</strong> University<br />
Goettingen, Goettingen, Germany<br />
<strong>19</strong>.32 - <strong>19</strong>.44 CE-MS based human urinary proteome database for<br />
biomarker discovery and disease diagnosis<br />
Petra Zürbig 1 , David M. Good 2 , Eric Schiffer 1 , Joshua J. Coon 2, 3<br />
and Harald Mischak 1<br />
1<br />
Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany<br />
2<br />
Department of Chemistry<br />
3<br />
Department of Biochemistry, University of Wisconsin University of Wisconsin-Madison,<br />
Madison, WI, USA,<br />
<strong>19</strong>.44 - <strong>19</strong>.56 Urinary proteomic biomarkers in coronary artery disease<br />
Eric Schiffer 1 , Lukas U. Zimmerli 2 , Janet K. Snell-Bergeon 3 ,<br />
David M. Maahs 3 , Harald Mischak 1 , and Anna F. Dominiczak 4<br />
1<br />
Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany<br />
2<br />
Division of Internal Medicine, University Hospital Zurich, Zurich, Switzerland<br />
3<br />
Barbara Davis Center for Childhood Diabetes, Aurora, USA<br />
4<br />
BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.<br />
<strong>19</strong>.56 - 20.08 A novel, non-invasive multiplex-assay to diagnose acute<br />
rejection in the urine of renal transplant recipients.<br />
Diana Breuer 1 . Gerald Schlaf 1 , Wolfgang Altermann 1 , Barbara<br />
Selinger 1 , Paolo Fornara 2 and Amir Hamza 2<br />
1 Martin-Luther-University Halle –Wittenberg, Medical School, HLS-Laboratory (GHATT)<br />
2<br />
Department or Urology and Kidney Transplant Center<br />
20.08 - 20.20 Influence of acid mucopolysaccharide in proteome analysis<br />
of non-protein urine<br />
Zhinguo Li, Tingting Zhao, Liping Yang, Jingzhen Guo, and Ping Li<br />
Department of Pharmacology, Institute of Clinical Medical Science, China-Japan Friendship<br />
Hospital, Beijing, P.R. China<br />
20.20 - 20.40 Session 2<br />
New Activity of HKUPP<br />
Chair: Yutaka Yoshida (Niigata University, Japan)<br />
20.20 - 20.30 News from HUPO<br />
Tadashi Yamamoto<br />
Department of Structural Pathology, Institute of Nephrology, Graduate School of Medical<br />
and Dental Sciences, Niigata University, Niigata, Japan<br />
20.30 - 20.40 News from EuroKUP<br />
Antonia Vlahou<br />
Biomedical Research Foundation of the Academy of Athens, Athens, Greece<br />
20.40 - 21.00 Session 3<br />
Free Discussion<br />
Chair: Visith Thongboonkerd (Mahidol University, Bangkok, Thailand)<br />
Model Organisms Workshop<br />
room: CD<br />
18.30 - 21.00<br />
Chairs: Michael Hengartner, Ruedi Aebersold, Sabine Schrimpf<br />
Invitees: Matthias Mann, Steven Gygi, Albert Heck, Young-Ki Paik, Rolf Apweiler, Klaas<br />
van Wijk, Richard Smith, Lennart Markus, Mike McCoss, Steven Briggs, Phil Andrews<br />
18.30<br />
18.50<br />
<strong>19</strong>.10<br />
How to compile proteomes reliably<br />
Matthias Mann<br />
How to analyze data and how to make the data accessible and<br />
exchangeable efficiently<br />
Alexey I. Nesvizhskii<br />
How to make the data accessible and exchangeable efficiently<br />
Ruedi Aebersold<br />
The following discussion until 21.00 will be about the possibility/necessity/organization<br />
of a new HUPO initiative in “model organism proteomes”.<br />
28 29
Solutions for protein stabilization, separation,<br />
purification, and analysis<br />
Stop by BD Booth 80<br />
to learn more about<br />
our proteomics offering:<br />
BD P100 and P700 Blood Collection Tubes –<br />
stabilize plasma proteins for biomarker<br />
discovery and metabolic studies<br />
BD FFE – obtain high resolution separation<br />
and purification of proteins, peptides<br />
and cell organelles<br />
Phosflow – multiplexed activation-state<br />
analysis of rare cell types in complex primary<br />
samples and simultaneous correlation of<br />
multiple phosphorylation <strong>event</strong>s<br />
For more information visit:<br />
www.bd.com/proteomics<br />
www.bdphosflow.com<br />
Visit BD<br />
at Booth<br />
80<br />
BD Diagnostics<br />
Preanalytical Systems<br />
1 Becton Drive<br />
Franklin Lakes, NJ 07417<br />
Sunday 17 <strong>August</strong> 2008<br />
location <br />
Exhibition hall 10 Room Forum Room A Room B Room CD Room EF<br />
time <br />
whole day Exhibition build-up Clinical Day<br />
HUPO<br />
Plasma Proteome<br />
Initiative<br />
HUPO<br />
Proteomics Standards<br />
09.00 - 12.00<br />
HUPO Cardiovascular<br />
Proteome Initiative<br />
HUPO<br />
Glycomics Initiative<br />
Workshop<br />
09.00 - 12.25<br />
Clinical Day<br />
Session I<br />
09.30 - 12.00<br />
Clinical Day<br />
Session II<br />
13.30 - 17.30<br />
18.30 - 21.00<br />
Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />
= Initiative = Other meeting<br />
BD, BD Logo and all other trademarks are property of Becton, Dickinson and Company. © 2008 BD<br />
30 31
Sunday 17 <strong>August</strong><br />
Biomarkers from Discovery to Clinical Application,<br />
Industry & Academia Views<br />
09.00 - 17.30<br />
room: Forum<br />
09.00 - 10.20 Biomarker Discovery & Implementation Perspectives<br />
09.00 - 09.40 Victor Jongeneel, Vice President for Research,<br />
The Cyprus Institute in Nicosia, Cyprus<br />
09.40 - 10.20 The Road to Diagnostic Proteomics: How far have we come?<br />
Sudhir Srivastava, NCI, Bethesda, USA<br />
10.20 - 10.40<br />
Coffeebreak<br />
10.40 - 12.25 Biomarkers for Heart, Liver & Pregnancy<br />
10.40 - 11.15 Heart disease biomarkers<br />
Hendrik Milting, Heart Centre, Bad Oeynhausen, Germany<br />
11.15 - 11.50 New biomarkers related to Preeclampsia<br />
Thomas Brinkmann, Beckman Coulter<br />
11.50 - 12.25 Discovery & Validation of Liver Biomarkers<br />
Kai Stuehler, Medizinisches Proteom-Center, Bochum, Germany<br />
12.25 - 13.30<br />
Lunch break on-site<br />
13.30 - 15.30 Biomarkers for Brain & Kidney Diseases<br />
13.30 - 14.00 Brain Stroke Biomarker Discovery<br />
Jean-Charles Sanchez, Geneva, Switzerland<br />
14.00 - 14.30 “S100B - a biomarker for Brain injury”<br />
Susanne Grüb, Roche, Basel, Switzerland<br />
14.30 - 15.00 Protein Profiles as Biomarker for Kidney Diseases<br />
Harald Mischak, Mosaique Diagnostics, Hannover, Germany<br />
15.00 - 15.30 Autoimmune Antibodies as Biomarkers for<br />
Neurodegenerative Diseases<br />
Stefan Müllner, Protagen AG, Dortmund, Germany<br />
15.30 - 16.00<br />
Coffee break<br />
16.00 - 16.30 Glyco-Biomarkers for Cancer<br />
16.00 - 16.30 Glycoproteins as Cancer Biomarker<br />
Naoyuki Tanaguchi, Osaka University, Japan<br />
16.30 - 17.30<br />
hupo clinical day<br />
Panel Discussion<br />
Biomarker from Discovery to Clinical Application<br />
What is the right way to succeed?<br />
Panellists from Industry, Academy & Agencies<br />
hupo initiatives program<br />
HUPO Glycomics Initiative Workshop<br />
09.30 - 12.00<br />
Chairs: Naoyuki Taniguchi, James Paulson and Hisashi Narimatsu<br />
room: A<br />
09.30 - 09.35 Welcome and Introduction of HGPI and the pilot studies<br />
N. Taniguchi (Osaka University)<br />
09.35 - 10.00 Report on the second HGPI pilot study-Comparison of the<br />
methods for profiling glycoprotein O-glycans<br />
S. Haslam and A. Dell (Imperial College)<br />
10.00 - 10.15 Glycan structural analysis of glycoproteins using O-linked<br />
glycan libraries<br />
H. Ito and H, Narimatsu<br />
(Advanced Institute for Science and Technology)<br />
10.15 - 10.30 Increased sensitivity in the profiling of mucin O-glycans with<br />
negative mode nanoLC-mass spectrometry<br />
K.A. Thomsson, M. Backstrom, H. Karlsson, and G.C. Hansson<br />
(University of Gothenburg)<br />
10.30 - 10.50 “Horses for Courses: Bringing glycan analysis to biologists”<br />
N. Packer, P. Jensen, A. Lee, N, Deshpande, M, Nakano, and D,<br />
Kolarich. (Macquarie University)<br />
10.50 - 11.10 Aberrant O-glycosylation of IgA1 and the Pathogenesis of<br />
IgA Nephropathy<br />
M. Renfrow<br />
11.10 - 11.30 “Malectin - a candidate player in the folding/quality control of<br />
N-glycoproteins and disorders underlying human diseases”<br />
Ten Feizi (Imperial College)<br />
11.30 - 11.50 Biomarker for stem cells<br />
M. Pierce (University of Georgia)<br />
General Discussion<br />
Catherine Costello (Boston University)<br />
HUPO Cardiovascular Proteomics Initiative<br />
room: B<br />
09.00 - 12.00<br />
Chairs: Peipei Ping (Los Angeles, USA), Mario Hugo Genero (Buenos Aires, Argentina)<br />
and Thomas Vondriska (Los Angeles, USA)<br />
09.00 Keynote Lecture<br />
Susan Old, NHLBI, USA<br />
09.45 Featured Talk<br />
MingMing Ning, Boston, USA<br />
32 33
10.05 Featured Talk<br />
Fernando Vivanco, Madrid, Spain<br />
10.25 Featured Talk<br />
Arjen Scholten, Utrecht, The Netherlands<br />
10.50 Featured Talk<br />
Ruth Lovering, London, UK<br />
11.30 Round Table Discussion<br />
“HUPO CVI: Components of the Human Proteome Project”.<br />
Frank Vitzthum, Manuel Mayr, Susan Old, Jennifer Van Eyk, Peipei Ping.<br />
HUPO Proteomics Standards Initiative (PSI)<br />
room: CD<br />
09.30 - 12.00<br />
Session chair: Pierre-Alain Binz, Swiss Institute of Bioinformatics, Geneva, Switzerland<br />
The HUPO Proteomics Standards Initiative (PSI) defines community standards for data<br />
representation in proteomics to facilitate data comparison, exchange and verification.<br />
We will present recent progress across PSI work groups, both in the development of<br />
standards, and in the collaboration with journal editors on implementation of standards<br />
as part of the scientific publishing process.<br />
1. Design and implementations of the new PSI’s mass spectrometer<br />
output file standard format: mzML 1.0<br />
Jim Shofstahl, Thermo Electron, San Jose, USA<br />
2. Recent progress on analysisXML, the mass spectrometry analysis format<br />
Martin Eisenacher, “Medizinisches Proteom-Center”,<br />
Ruhr-Universität Bochum, Germany<br />
3. PEFF, a common sequence database format in proteomics<br />
Pierre-Alain Binz, Swiss Institute of Bioinformatics, Geneva, Switzerland<br />
4. Molecular Interaction Standards – from file format to confidence scoring<br />
Sandra Orchard, European Bioinformatics Institute, Cambridge, UK<br />
Human Plasma Proteome Initiative Workshop<br />
09.30 - 12.00<br />
Chairs: Gil Omenn, Ruedi Aebersold and Young-Ki Paik<br />
room EF<br />
1. Technology Platforms<br />
led by Ruedi Aebersold<br />
2. Informatics Platforms and Repositories<br />
led by Eric Deutsch and Lennart Martens<br />
3. Engagement of research groups for submission of major datasets<br />
led by Gil Omenn & Young-Ki Paik<br />
4. Integration across HUPO Initiatives, featuring chairs of other HUPO<br />
initiatives<br />
Monday 18 <strong>August</strong> 2008<br />
location <br />
Room M Room B Room CD Room EF<br />
Room<br />
N-N1-O1-O<br />
Room Forum Room A Room L<br />
Room<br />
Auditorium<br />
Forum Ground<br />
Floor<br />
time <br />
Speaker Ready<br />
Room<br />
Registration &<br />
Information<br />
whole day<br />
Corporate Workshop<br />
Promega<br />
Corporate Workshop<br />
Qiagen<br />
07.00 - 07.50<br />
08.00 - 08.45 Tony Pawson<br />
08.45 - 09.30 Hans Clevers<br />
09.30 - 11.00 Break & Posters in Exhibition Hall 10<br />
S5<br />
Standards for<br />
Clinical Proteomics<br />
S4<br />
Mass Spectrometric<br />
Innovations<br />
S3<br />
Innovation in Peptide &<br />
Protein Separation<br />
Technologies<br />
S2<br />
Molecular Mass<br />
Imaging<br />
S1<br />
Reagents for<br />
proteomics<br />
11.00 - 12.30<br />
Corporate Workshop<br />
Bruker Daltonics<br />
Corporate Workshop<br />
Applied Biosystems<br />
Corporate Workshop<br />
Agilent Technologies<br />
12.30 - 14.00 Lunch, Poster Session & Exhibition in Exhibition Hall 10<br />
S10<br />
Cardiovascular<br />
Proteome Biology<br />
S9<br />
Yeast proteomics;<br />
sparks for new biology<br />
S8<br />
C. elegans and<br />
Drosophila<br />
S7<br />
Plant proteomics<br />
S6<br />
Organelle and biological<br />
membranes Proteomics<br />
14.00 - 15.30<br />
15.30 - 16.00 Break & Posters in Exhibition Hall 10<br />
16.00 - 16.30 Opening Ceremony<br />
16.30 - 17.15 Mathias Uhlén<br />
17.15 - 18.00 Ruedi Aebersold<br />
18.00 - <strong>19</strong>.00 Welcome Reception<br />
Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />
= Initiative = Other meeting<br />
34 35
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©2008 Promega Corporation, 16759-AD-GN<br />
The Night Watch, 1642<br />
Rembrandt van Rijn 1606-1669<br />
Rijksmuseum, Amsterdam<br />
The title of the Night Watch seems to refer to the content of this famous painting, but was introduced<br />
in the 18th century, based on a misapprehension due to dulling of the painting’s surface. However, it<br />
is a day lit scene.<br />
The original title of the Night Watch was: The Company of Frans Banning Cocq and Willem van<br />
Ruytenburch. Rembrandt depicted a division of the civic guard, called Arquebusiers after the arquebus,<br />
a sixteenth-century long-barrelled gun. He displayed the traditional emblem of the Arquebusiers in a<br />
natural way. The chicken claws on the belt of the girl in the yellow dress represent the ‘Clauweniers’-<br />
Arquebusiers. The long-barreled gun, the arquebus, is clearly visible against her yellow dress. The man<br />
in front of her is wearing a helmet with an oak leaf - a traditional motif of the Arquebusiers.<br />
Interestingly, only those who paid were included in the group portrait. Except for the drummer, who<br />
was hired and therefore allowed to be in the painting for free. It is said that Rembrandt cleverly<br />
included himself in the background of this painting. His eye, nose, part of his forehead, and his painter’s<br />
beret are visible above the Captain’s head.<br />
36 37
Plenary Speakers Monday<br />
Tony Pawson<br />
Hans Clevers<br />
BIOGRAPHY<br />
Tony Pawson was an undergraduate at the University of Cambridge (<strong>19</strong>70-<strong>19</strong>73),<br />
obtained his Ph.D. at the Imperial Cancer Research Fund, London, and did postdoctoral<br />
work at the University of California at Berkeley (<strong>19</strong>76-<strong>19</strong>80). He moved to the University<br />
of British Columbia as an Assistant Professor, and then to the Samuel Lunenfeld<br />
Research Institute of Mt. Sinai Hospital, University of Toronto in <strong>19</strong>85, where he<br />
was Director of Research (2000-2005). Over the last 25 years he has explored the<br />
mechanisms through which modular protein-proteins interactions control intracellular<br />
signaling networks, building on the identification of the SH2 domain as the prototypic<br />
interaction module.<br />
abstract<br />
Proteomic analysis of reciprocal cell signalling<br />
T. Pawson, C. Jorgensen, A. Sherman, Samuel Lunenfeld Reseach Institute<br />
Mt. Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada<br />
Signaling proteins are typically constructed in a modular fashion, from domains<br />
that mediate either molecular interactions or catalytic <strong>event</strong>s, and corresponding<br />
interaction or substrate motifs. The joining of domains in new combinations can provide<br />
novel functions in evolution, both by creating new intermolecular connections, and by<br />
forming new and varied modes of allosteric regulation. This notion will be discussed in<br />
the context of cytoplasmic tyrosine kinases such as Fes and Abl.<br />
Intercellular signaling is typically investigated experimentally in the context of a signal,<br />
such as a growth factor, impinging on a receptor on a target cell. In vivo, however,<br />
neighboring cells often signal back-and-forth in a reciprocal fashion. We have used a<br />
combination of proteomic and functional screens to investigate the means by which<br />
cells exchange and respond to such two-way signals, using phosphotyrosine-based<br />
intracellular networks.<br />
BIOGRAPHY<br />
Hans Clevers obtained his MD degree in <strong>19</strong>84 and his PhD degree in <strong>19</strong>85 from the<br />
University of Utrecht, the Netherlands. His postdoctoral work (<strong>19</strong>86-<strong>19</strong>89) was done<br />
with Cox Terhorst at the Dana-Farber Cancer Institute of the Harvard University,<br />
Boston, USA.<br />
From <strong>19</strong>91-2002, Hans Clevers was Professor in Immunology at the University of<br />
Utrecht and, since 2002, Professor in Molecular Genetics. Since 2002, he is Director<br />
of the Netherlands Institute for Developmental Biology, Utrecht.<br />
Hans Clevers has been a member of the Royal Dutch Academy of Sciences since 2000<br />
and is the recipient of several awards, including the Dutch Spinoza Award in 2001, the<br />
Swiss Louis Jeantet Prize in 2004, the Memorial Sloan-Kettering Katharine Berkan<br />
Judd Award in 2005 and the Israeli Rabbi Shai Shacknai Memorial Prize in 2006.<br />
abstract<br />
Identification of stem cells in small intestine and colon by a single marker gene lgr5<br />
H. Clevers, Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands<br />
The intestinal epithelium is the most rapidly self-renewing tissue in adult mammals.<br />
Current models state that 4-6 crypt stem cells reside at the +4 position immediately<br />
above the Paneth cells in the small intestine; colon stem cells remain undefined. Lgr5/<br />
Gpr49 was selected from a panel of intestinal Wnt target genes for its restricted<br />
crypt expression. Two knock-in alleles revealed exclusive expression of Lgr5 in cycling,<br />
columnar cells at the crypt base. In addition, Lgr5 was expressed in rare cells in<br />
several other tissues. Using an inducible Cre knock-in allele and the Rosa26-LacZ<br />
reporter strain, lineage tracing experiments were performed in adult mice. The<br />
Lgr5+ve crypt base columnar cell (CBC) generated all epithelial lineages over a 60-day<br />
period, implying that it represents the stem cell of the small intestine and colon. The<br />
expression pattern of Lgr5 suggests that it marks stem cells in multiple adult tissues<br />
and cancers.<br />
38 39
Mathias Uhlén<br />
Ruedi Aebersold<br />
BIOGRAPHY<br />
Mathias Uhlén is Professor of Microbiology at the Royal Institute of Technology (KTH),<br />
Stockholm, Sweden. Prof. Uhlén is member of the Royal Swedish Academy of Engineering<br />
Science (IVA), the Royal Swedish Academy of Science (KVA) and the European Molecular<br />
Biology Organization (EMBO). He is Vice-President of the European Proteomics<br />
Association (EuPA) and member of the Human Proteome Organization (HUPO) council.<br />
He was Vice-President of the Royal Institute of Technology (KTH), responsible for<br />
external relations, from <strong>19</strong>99 to 2001 and he was the chairman of the Swedish<br />
Biochemical and Molecular Biology Society (SFMB) from <strong>19</strong>94 to <strong>19</strong>99. Prof. Uhlén has<br />
more than 300 publications in bioscience with the focus on the development and use<br />
of affinity reagents in biotechnology and biomedicine.<br />
abstract<br />
A Human Protein Atlas<br />
Mathias Uhlén<br />
Royal Institute of Technology, School of Biotechnology, AlbaNova University Center,<br />
Stockholm, Sweden, +46 8 5537 8325, E-mail: mathias@biotech.kth.se<br />
The new version 4.0 of the Human Protein Atlas (www.proteinatlas.org) has been<br />
generated with more than 6,000 validated antibodies corresponding to 5,000 human<br />
genes. The portal contains more than 4 million high-resolution images generated<br />
by immunohistochemistry and confocal microscopy. Each image has been manually<br />
annotated and curated by a certified pathologist to provide a knowledge base for<br />
functional studies and to allow searches and queries about protein profiles in normal<br />
and disease tissue. A new structure has been implemented with the inclusion of all<br />
predicted genes (approximately 20,500) with a visualization of the encoded protein<br />
characteristics for all genes. A new search tool is also launched in which advance<br />
queries can be performed, including searches for chromosome location, protein class<br />
and/or tissue specificity. Our results suggest that it should be possible to extend<br />
the protein atlas to a majority of all human proteins thus providing a valuable tool for<br />
medical and biological research.<br />
Berglund et al (2008) “The epitope space of the human proteome” Protein Science 17, 606-613.<br />
Björling et al (2008) “A web-based tool for in silico biomarker discovery based on tissue-specific protein profiles in normal and<br />
cancer tissues” Mol Cell Proteomics 7(5): 825-44.<br />
Barbe et al (2008) “Toward a confocal subcellular atlas of the human proteome” Mol Cell Proteomics. 7(3):499-508<br />
BIOGRAPHY<br />
Ruedi Aebersold is the Professor for Molecular Systems Biology at ETH Zurich and<br />
the University of Zurich, Switzerland and co-founder of the Institute for Systems<br />
Biology in Seattle, WA. Research in his group is focused on the development and the<br />
application of proteomics technologies towards a better understanding of biological<br />
systems and processes.<br />
abstract<br />
Proteome biology<br />
Ruedi Aebersold - ETH Zurich, Switzerland, Institute of Molecular Systems Biology, USA<br />
aebersold@imsb.biol.ethz.ch<br />
Biological processes can be viewed as networks of interacting components, whereby<br />
the structure and dynamics of the network determines the properties of the process.<br />
Different types of such networks concurrently exist in the cell and many consist of or<br />
contain proteins. Examples include protein:protein interaction networks, networks of<br />
enzymes and their substrates, networks of microRNA’s and their targets, protein:DNA<br />
interaction networks etc. The study of such networks requires proteomic technologies<br />
that are capable of detecting and quantifying any protein of a given network, to<br />
determine the network connections and their dynamic change and to relate the results<br />
of measurements made on cell or tissue extracts back to the living cell.<br />
In this presentation we will discuss technical and conceptual advances in proteomics<br />
that support proteome biology. These include the ability to detect reliably and quantify<br />
essentially any protein in a yeast cell by targeted, SRM based high sensitivity mass<br />
spectrometry, the ability to determine the true composition of protein complexes<br />
that exist in the cell and to visualize them in near life cells, and the ability to measure<br />
phosphorylation modulated regulatory networks. The technical advances will be<br />
illustrated with suitable examples.<br />
40 41
Full Program details<br />
Monday 18 <strong>August</strong><br />
8.00-8.45 Plenary 1 Proteomic analysis of reciprocal cell signaling room: Auditorium<br />
Tony Pawson (Samuel Lunenfeld Research Institute, CANADA),<br />
claus Jorgensen, Andrew Sherman<br />
Chairperson: Anne-Claude Gavin<br />
8.45-9.30 Plenary 2 IDENTIFICATION OF STEM CELLS IN SMALL INTESTINE AND Room: Auditorium<br />
COLON BY A SINGLE MARKER GENE LGR5<br />
Hans Clevers (Hubrecht Institute, THE NETHERLANDS)<br />
Chairperson: Albert Heck<br />
S3 Innovation In Peptide & Protein Separation Technologies Room: A 11.00-12.30<br />
Chairpersons: Rong Zeng & Martijn Pinkse<br />
Separation and Identification of Phosphopeptides Based on Multiple Dimensional Liquid 11.00-11.30<br />
Chromatography Mass Spectrometry<br />
Jie Dai, Qing-Run Li, Chia-Hui Shieh, Rong Zeng (Shanghai Institutes for Biological Sciences, CHINA)<br />
Coupling Immobilized Enzyme Microreactors with MICRORPLC-MS/MS for Protein Analysis 11.30-11.50<br />
Junfeng Ma (Dalian Institute of Chemical Physics, Chinese Academy of Sciences, CHINA), Lihua Zhang,<br />
Zhen Liang, Yukui Zhang<br />
3D-GEL Electrophoresis, A New Approach to Comparative Protein Analysis 11.50-12.10<br />
Robert Ventzki (European Molecular Biology Laboratory, GERMANY), Sjouke Hoving, Jan van Oostrum,<br />
Josef Stegemann<br />
High Sensitivity RP/RP/LC/MS Platform for Assessing Protein Complex Dynamics 12.10-12.30<br />
Scott Ficarro (Dana-Farber Cancer Institute, UNITED STATES), Feng Zhou, Guillaume Adelmant, Job Cardoza,<br />
Manor Askenazi, Jarrod Marto<br />
11.00-12.30 S1 Reagents For Proteomics room: Auditorium<br />
Chairpersons: Andreas Plückthun & Hermen Overkleeft<br />
11.00-11.30 Novel binding proteins by design and evolution<br />
Andreas Plückthun (University of Zurich, SWITZERLAND)<br />
11.30-11.50 Antibody QA Pipeline For Proteomics Researchers: Nci’s Antibody Characterization Program<br />
Henry Rodriguez, Mehdi Mesri, Gordon Whiteley, Chris Kinsinger (National Cancer Institute/National Institutes<br />
of Health, UNITED STATES)<br />
11.50-12.10 Fluorescent Isotope Coded Affinity Tag (FCAT) for Quantitative Proteomics<br />
Andras Guttman (Horvath Laboratory of Bioseparation Sciences, AUSTRIA), Zuly Rivera<br />
12.10-12.30 Design of Recombinant SCFV Antibodies for High-Throughput Affinity-Based Proteomics<br />
Malin Kristensson (Lund University, SWEDEN), Jacob Vallkil, Katarina Loof, Carl AK Borrebaeck, Christer Wingren<br />
S4 Mass Spectrometric Innovations Room: L 11.00-12.30<br />
Chairperson: Carol Robinson<br />
Subunit Architecture of Multiprotein Complexes Isolated Directly from Cells - Insights from 11.00-11.30<br />
Mass Spectrometry of Intact Complexes<br />
Caron Robinson (University of Cambridge, UNITED KINGDOM), H Hernández, AM Sandercock, M Zhou,<br />
B Ruotolo, T Nelson, P Barrera<br />
High Resolution Mass Spectrometry to Study Functional Protein Complexes 11.30-11.50<br />
Esther van Duijn (Utrecht University, THE NETHERLANDS), Charlotte Uetrecht, Arjen Barendregt,<br />
Kees Versluis, Albert Heck<br />
Microfluidic Platform for ESI (DESI) and MALDI (LDI) Shotgun Proteomic Analysis 11.50-12.10<br />
Daniel Knapp (Medical University of South Carolina, UNITED STATES), Jian Liu, Ranu Nayak, Daniel Higbee<br />
Targeted Peptide Identification Based on Selected Reaction Monitoring 12.10-12.30<br />
Bruno Domon (ETH Zurich, SWITZERLAND), Paola Picotti, Nathalie Selevsek, Ruedi Aebersold<br />
11.00-12.30 S2 Molecular Mass Imaging room: Forum<br />
Chairperson: Richard Caprioli<br />
11.00-11.30 Molecular Imaging and Profiling of Tissues with Mass Spectrometry:<br />
applications in Biological and Clinical Research<br />
Richard Caprioli (Vanderbilt University, UNITED STATES)<br />
11.30-11.50 Direct Mass Spectromectric Imaging of Human Brain Tissue<br />
Ron M.A. Heeren (FOM Institute for Atomic and Molecular Physics, THE NETHERLANDS), Kükrer Kaletas,<br />
Ingrid van der Wiel, Jonathan Stauber, Lennart Dekker, C. Güzel, Theo M. Luider<br />
11.50-12.10 Protein Unlocking of Formalin Stored (FFPE) Tissues: Application to MALDI-TOF-IMAGING-MS<br />
Maurizio Ronci (European Centre for Brain Research (CERC), Fondazione - Santa Lucia, ITALY), Elena Bonanno,<br />
Alfredo Colantoni, Luisa Pieroni, Carmine di Ilio, Luigi Giusto Spagnoli, Giorgio Federici, Andrea Urbani<br />
12.10-12.30 On Tissue Fractionation: Unmasking Difficult Proteins for MALDI profiling<br />
Isabelle Fournier (University of Lille 1, Laboratoire de Neuroimmunologie des Annelides, FRANCE),<br />
David Bonnel, Julien Franck, Maxence Wisztorski, Mohamed El Ayed, Michel Salzet<br />
S5 Standards For Clinical Proteomics room: N-N1-O1-O 11.00-12.30<br />
Chairpersons: Henry Rodriguez & Christian Stephan<br />
Introduction by Henry Rodriguez 11.00-11.10<br />
Performance and Optimization of LC-MS/MS Platforms for Proteomic Analyses: An Interlaboratory Study 11.10-11.30<br />
Daniel Liebler (Vanderbilt University School of Medicine, UNITED STATES), Amanda Paulovich<br />
Verification of Candidate Protein Biomarkers: Reproducibility of MRM-BASED Assays 11.30-11.50<br />
Steven Hall (University of California San Francisco, UNITED STATES), Terri Addona, Steven Skates, David Bunk<br />
Measures of Variability in Shotgun Proteomics Experiments 11.50-12.10<br />
Steve Stein (National Institute of Standards and Technology, UNITED STATES), Lisa Kilpatrick,<br />
Yuri Mirokhin, Paul Rudnick, Dmitrii Tchekhovskoi, Eric Yan, Xiouyu Yang<br />
Absolute Silac for Accurate Quantitation of Proteins in Complex Mixtures Down to the Attomole Level 12.10-12.30<br />
Stefan Hanke (Max-Planck-Institute for Biochemistry, Dept of Proteomics and Signal Transduction, GERMANY),<br />
Hüseyin Besir, Dieter Oesterhelt, Matthias Mann<br />
42 43
Full Program details<br />
Monday 18 <strong>August</strong><br />
14.00-15.30 S6 Organelle And Biological Membranes Proteomics room: Auditorium<br />
Chairpersons: John Bergeron & Bert Poolman<br />
14.00-14.30 The Protein Microscope and Organellar Proteomics<br />
John Bergeron (McGill University, CANADA), Catherine Au, Michael Jain, Jeff Smirle, Alexander Bell, Tommy Nilsson<br />
14.30-14.50 Membrane Proteome of the Yeast Nuclear Envelope<br />
L.M. Veenhoff (University of Groningen, THE NETHERLANDS), J.A. Demmers, M.C. King, A.C. Meinema, B. Poolman<br />
14.50-15.10 Organelle Mapping of the Human Proteome - Towards a Subcellular Atlas<br />
Emma Lundberg (School of biotechnology, Royal institute of Technology (KTH), SWEDEN), Laurent Barbe,<br />
Per Oksvold, Anna Stenius, Erik Björling, Anna Asplund, Fredrik Pontén, Hjalmar Brismar, Mathias Uhlén,<br />
Helene Andersson-Svahn<br />
15.10-15.30 Proteome of Hydrogenosomes and Mitosomes<br />
Petr Jedelsky (Charles University in Prague, Faculty of Science, CZECH REPUBLIC), Miroslava Sedinova,<br />
Petr Rada, Neritza Campo Beltran, Jan Tachezy<br />
S9 Yeast Proteomics; Sparks For New Biology room: L 14.00-15.30<br />
Chairpersons: Mike Tyers & Liesbeth Veenhoff<br />
Systematic Interrogation of the Budding Yeast Kinome 14.00-14.30<br />
Ashton Breitkreutz, Brett Larsen, Hyungwon Choi, Zhen-Yuan Lin, Jeff Sharom, Lorrie Boucher, Danielle Dewar,<br />
Rune Linding, Tony Pawson, Anne-Claude Gingras, Alexey Nesvizhskii, Mike Tyers (Samuel Lunenfeld Research Institute,<br />
Mount Sinai Hospital, CANADA, Wellcome Trust Centre for Cell Biology, School of Biological Sciences,<br />
University of Edinburgh, UNITED KINGDOM)<br />
An in Vivo Map of the Yeast Protein Interactome 14.30-14.50<br />
Kirill Tarassov, Vincent Messier, Christian R. Landry, Stevo Radinovic, Mercedes M. Serna Molina, Igor Shames,<br />
Yelena Malitskaya, Jackie Vogel, Howard Bussey, Stephen W. Michnick (Département de Biochimie,<br />
Université de Montréal, Centre Robert-Cedergren, Bio-Informatique et Génomique, CANADA)<br />
The Yeast Nuclear Proteome: Composition and Complexes 14.50-15.10<br />
Sharon Gauci (Utrecht University, THE NETHERLANDS), Liesbeth M. Veenhoff, Albert J. R. Heck, Jeroen Krijgsveld<br />
Analysis of the S. Cerevisiae Metabolic Network by Targeted Proteomics 15.10-15.30<br />
Paola Picotti (Institute of Molecular Systems Biology, ETH Zuerich, SWITZERLAND), Anne Kuemmel, Roeland Costenoble,<br />
Henry Lam, David Campbell, Matthias Heinemann, Eric Deutsch, Uwe Sauer, Bruno Domon, Ruedi Aebersold<br />
14.00-15.30 S7 Plant Proteomics room: Forum<br />
chairperson: Steven Briggs<br />
14.00-14.30 Quantitative Changes in the Arabidopsis Proteome Caused by Pathogen Signals<br />
SP Briggs (University of California San Diego, UNITED STATES), Z Shen, C van Schie, A Mason, S Payne,<br />
N Castellana, V Bafna, EH Chung, J Dangl<br />
14.30-14.50 Digging Into the Plant Proteome<br />
Sergey Sikora (GenWay Biotech, Inc, UNITED STATES), Lei Huang, Xiangming Fang<br />
14.50-15.10 Proteomic Analysis of the Endophytic Interaction of Gluconacetobacter Diazotrophicus with Sugarcane<br />
Leticia Lery (Unidade Multidisciplinar de Genômica, Universidade Federal do Rio de Janeiro, BRAZIL),<br />
Eduardo Nogueira, Wanda von Kruger, Adriana Hemerly, Paulo Bisch<br />
15.10-15.30 Profiling of Receptor-like Kinases Membrane Protein Family in Arabidopsis Thaliana<br />
Fabrizia Fusetti (Department of Biochemistry, University of Groningen, THE NETHERLANDS),<br />
Hamid Najafi Zarrini, Wim Huibers, Theo Elzenga, Frank Lanfermijer, Bert poolman<br />
S10 Cardiovascular Proteome Biology roomN-N1-O1-O 14.00-15.30<br />
Chairpersons: Peipei Ping & Arjen Scholten<br />
Session sponsored by<br />
The Dynamics of Mitochondrial Proteome in the Murine Heart 14.00-14.30<br />
Peipei Ping (UCLA, UNITED STATES)<br />
Development of a Novel Immunoassay for Characterizing Circulating Form of Cardiac Troponin 14.30-14.50<br />
Jennifer Van Eyk (Bayview proteomics center, Johns Hopkins University, UNITED STATES), Yixin lin, Qin Fu<br />
Nitric Oxide Induced Changes of the Heart Phosphoproteome 14.50-15.10<br />
Annamária Simon (Institute of Cardiovascular Physiology, Heinrich-Heine-University of Düsseldorf, GERMANY),<br />
Michael Reinartz, Ulrich Flögel, Jürgen Schrader<br />
Profiling Protein Expression in Human Dilated Cardiomyopathy; Global and Targeted Analyses 15.10-15.30<br />
Arjen Scholten (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht University, THE NETHERLANDS),<br />
Thin-Thin Aye, Marcel van der Heyden, Marc Vos, Toon van Veen, Albert Heck<br />
14.00-15.30 S8 C. Elegans And Drosophila room: A<br />
Chairpersons: Michael Hengartner & Michael O. Glocker<br />
14.00-14.30 Idenfication and Characterization of the C. Elegans Proteome<br />
Michael Hengartner (University of Zurich, SWITZERLAND)<br />
14.30-14.50 System-Wide Analysis of Phosphatase Knock-Down in Drosophila by Quantitative Proteomics<br />
Maximiliane Hilger (Department of Proteomics and Signal Transduction, Max-Planck Institute for<br />
Biochemistry, GERMANY), Tiziana Bonaldi, Florian Gnad, Chanchal Kumar, Jürgen Cox, Matthias Mann<br />
14.50-15.10 Genome-Wide Characterization of Proteins Involved in Cell-Cycle Regulation<br />
Mikael Björklund (University of Helsinki and National Public Health Institute, FINLAND), Mikko Turunen,<br />
Martin Bonke, Maria Sokolova, Minna Taipale, Jussi Taipale<br />
Plenary 3 A HUMAN PROTEIN atlas room: Auditorium 16.30-17.15<br />
Mathias Uhlén (AlbaNova University Center, SWEDEN)<br />
Chairperson: Peipei Ping<br />
Plenary 4 Proteome Biology room: Auditorium 17.15-18.00<br />
Ruedi Aebersold (ETH Zürich, SWITZERLAND<br />
institute of Molecular Systems Biology, United States)<br />
Chairperson: Denis Hochstrasser<br />
1510-1530 QUANTITATIVE PROTEOME ATLAS OF THE ADULT HONEY BEE CASTES<br />
Queenie Chan (University of British Columbia, CANADA), Yuan Fang, Man Yi Chan, Michelle Logan,<br />
Heather Higo, Leonard Foster<br />
44 45
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First published Aug 2008<br />
GE Healthcare Bio-Sciences AB, Björkgatan 30, 751 84 Uppsala, Sweden<br />
GE11-08<br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong> 2008<br />
location <br />
Room M Room B Room CD Room EF Room P<br />
Room<br />
N-N1-O1-O<br />
Room Forum Room A Room L<br />
Room<br />
Auditorium<br />
Forum Ground<br />
Floor<br />
time <br />
Speaker Ready<br />
Room<br />
Registration &<br />
Information<br />
whole day<br />
Corporate Workshop<br />
GE Healthcare<br />
Corporate Workshop<br />
Rosetta Bio<strong>software</strong><br />
07.00 - 07.50<br />
08.00 - 08.45 Peter Andrews<br />
08.45 - 09.30 Matthias Mann<br />
09.30 - 11.00 Break & Posters in Exhibition Hall 10<br />
S15<br />
Glycoproteomics<br />
S14<br />
Alternative splicing &<br />
protein processing<br />
S13<br />
EuPA Young<br />
Investigator Session<br />
S12<br />
Computational<br />
approaches to mine<br />
proteomic data<br />
S11<br />
Phosphoproteomics<br />
11.00 - 12.30<br />
Corporate Workshop<br />
Promega<br />
Corporate Workshop<br />
Bruker Daltonics<br />
Corporate Workshop<br />
Dionex<br />
Corporate Workshop<br />
Thermo Scientific<br />
12.30 - 14.00 Lunch, Poster Session & Exhibition in Exhibition Hall 10<br />
S20<br />
Proteomics of the<br />
nervous systems<br />
S<strong>19</strong><br />
Proteomics and<br />
epigenetics<br />
S18<br />
Proteomics of<br />
Macro-molecular<br />
Complexes<br />
S17<br />
Kinase-protein<br />
substrate networks<br />
S16<br />
Chemical<br />
Proteomics<br />
14.00 - 15.30<br />
15.30 - 16.00 Break & Posters in Exhibition Hall 10<br />
16.00 - 16.45 Anne-Claude Gavin<br />
16.45 - 17.30 Erin O’Shea<br />
HUPO General<br />
Assembly<br />
17.30 - <strong>19</strong>.30<br />
Translating biomarkers<br />
from the bench to<br />
the bedside<br />
(Salvatore Sechi)<br />
20.00 - 22.30<br />
Workshop on<br />
Proteomics Validation<br />
Sudhir Srivastava &<br />
William Hancock<br />
Publishing in<br />
Proteomics:<br />
A dialogue of investigators<br />
and journals<br />
(Peipei Ping)<br />
20.00 - 22.00<br />
Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />
= Initiative = Other meeting<br />
46 47
Plenary Speakers <strong>Tuesday</strong><br />
Peter Andrews<br />
Matthias Mann<br />
BIOGRAPHY<br />
Peter Andrews is Professor of Biomedical Science at Sheffield University, where he<br />
also co-directs the Centre for Stem Cell Biology. His research focuses on the biology<br />
of human ES cells. He co-ordinates the International Stem Cell Initiative, focused upon<br />
characterising human ES cells.<br />
abstract<br />
Population Dynamics, Self Renewal and Culture Adaptation of Human ES cells<br />
Peter W Andrews, Centre for Stem Cell Biology and Department of Biomedical Science,<br />
The University of Sheffield, Sheffield, S10 2TN, UK<br />
Teratocarcinomas, a subset of germ cell tumours, have long provided a paradigm for<br />
the stem cell concept of cancer, and the role of their stem cells, embryonal carcinoma<br />
(EC) cells, in their development is well known. Embryonic stem (ES) cells isolated<br />
from early embryos are the apparently ‘normal’ counterpart of tumour-derived EC<br />
cells. However, ES cells may acquire non-random karyotypic changes on prolonged<br />
culture. In human ES cells, these changes typically involve gain of genetic material<br />
from chromosomes 17, 12 and X, and resemble similar changes observed in EC cells<br />
from testicular teratocarcinomas, one of the most common cancers of young men.<br />
As a working hypothesis, we can imagine that the over expression of genes located<br />
on these chromosomes increases the probability of self renewal of pluripotent stem<br />
cells, at the expense of commitment to differentiation or apoptosis. A corollary is the<br />
proposition that these genes play a key role in regulating stem cell behaviour and their<br />
disruption may affect tumour progression, particularly in germ cell tumours, in which<br />
enhanced self renewal capacity might equate to a more aggressive tumour phenotype.<br />
A key problem is to identify the genes that contribute this type of selective overgrowth<br />
of variant stem cells in which they are over expressed. The available data suggest that<br />
only a relatively small number of genes is involved, maybe as few as five, but that these<br />
may act independently on different aspects of the control of stem cell behaviour.<br />
Identification of these genes would provide the basis for developing better techniques<br />
for ES cell culture to avoid selection pressure for over-expressing variants. It may<br />
also provide insights into the development and progression of teratocarcinomas, and<br />
provide a model for understanding other stem cell based cancers.<br />
BIOGRAPHY<br />
Matthias Mann received his doctorate degree from Yale University with John Fenn,<br />
where he contributed to the development of electrospray mass spectrometry. Prof.<br />
Mann is now a director at the Max-Planck Institute of Biochemistry in Martinsried,<br />
Germany. His group continues to develop proteomics technology and to address cell<br />
signaling problems using proteomics.<br />
abstract<br />
Spatio-temporal proteomics<br />
M. Mann - email: mmann@biochem.mpg.de, J.V. Olsen, C. Robles, C. Choudhary, N.C.<br />
Hubner, J. Graumann, J. Cox, F. Forner, C. Kumar and H. Serve*.<br />
Dept. of Proteomics and Signal Transduction, Max Planck Institute for Biochemistry,<br />
Am Klopferspitz 18, D-82512 Martinsried near Munich, Germany.<br />
*Dept. Internal Medicine, University of Frankfurt, Germany<br />
Mass spectrometry-based proteomics has usually been performed in a qualitative<br />
format although the community is rapidly realizing that biological conclusions can best<br />
be obtained from quantitative data. Quantitation allows measurement of spatial as<br />
well as temporal proteomes. This capability in turn makes proteomics an excellent<br />
complement to powerful imaging methods used in modern cell biology. Proteomics is<br />
unbiased and can be used in a ‘discovery mode’ whereas imaging technologies have<br />
higher sub-cellular resolution and are single cell based. Here I discuss recent technology<br />
developments and applications of quantitative proteomics combined with imaging<br />
technologies.<br />
Signalling can be different in quantity and quality depending on the intracellular compartment.<br />
Here we employed quantitative phosphoproteomics to show that the Flt3<br />
receptor with an internal tandem domain (ITD), which is the most common kinase<br />
mutation in Acute Myeloid Leukaemia, signals differently as a result of different compartmentalization.<br />
Temporal proteomics has first been demonstrated in the context of tyrosine signalling.<br />
Here we show that the temporal evolution of both the phosphoproteome and the<br />
proteome can be followed in SILAC based proteomics.<br />
Finally, we introduce PROSPECTS (Proteomics in Space and Time), a large European<br />
proteomics network, whose purpose is the elucidation of spatio-temporal proteomics<br />
by a combination of different technologies.<br />
48 49
Anne-Claude Gavin<br />
Erin O’Shea<br />
BIOGRAPHY<br />
Anne-Claude Gavin is Group Leader in the Structural and Computational Biology Unit<br />
at the European Molecular Biology Laboratory, Heidelberg. Before joining the EMBL<br />
she was a scientific director at Cellzome AG. In 2002 she received the Genome<br />
Technology All-Stars Award in proteomics. Her group has been proponent and pioneer<br />
of more general strategies aiming at understanding complex biological systems. With<br />
more than 1.500 citations, the system-wide characterization of protein complexes<br />
in a model eukaryote, Saccharomyces cerevisiae, by affinity purification and mass<br />
spectrometry is generally considered as a breakthrough. Her main research interest<br />
includes the study of biomolecular interaction, the understanding of the principles that<br />
govern the assembly and dynamics of protein networks.<br />
abstract<br />
The social network of a cell: dynamic protein interactions<br />
Anne-Claude Gavin, EMBL Heidelberg, Germany, gavin@embl.de<br />
Recent developments in the -omics field have provided comprehensive repertoires<br />
of RNAs, proteins, metabolites that constitute the cell building blocks. The next<br />
challenge resides in the understanding of how the “pieces” of this puzzle assemble,<br />
combine and contribute to the assembly of a coherent entity; a cell. Biology relies on<br />
the concerted action of a number interacting proteins and metabolites operationally<br />
organized in cellular pathways or networks. However, current appreciation of the “wiring<br />
diagram” or “molecular maps” of these pathways is scanty. We used tandem-affinity<br />
purification and mass spectrometry (TAP/MS) to perform a system-wide analysis for<br />
protein complexes in a model organism, budding yeast. The study provides one of the<br />
largest collections of physically-determined eukaryotic cellular machines. Beyond the<br />
repertoire, the analysis captures the modular nature of proteomes. In an attempt<br />
to move from static interaction networks to more dynamic maps, we developed an<br />
innovative scoring system that captures some biochemical properties of proteinprotein<br />
interaction: the likelihood to be in direct physical contact and, weakly, the<br />
dissociation constants. We believe that in the future, experimental and computational<br />
refinements may turn such scoring approaches into suitable parameters for rational<br />
modeling of (entire) systems.<br />
BIOGRAPHY<br />
Dr. O’Shea is an Investigator of the Howard Hughes Medical Institute, Director of<br />
the Harvard Faculty of Arts Sciences Center for Systems Biology and Professor of<br />
Molecular and Cellular Biology and Chemistry and Chemical Biology at Harvard University.<br />
She received her undergraduate degree from Smith College and her Ph.D. degree from<br />
the Massachusetts Institute of Technology. Dr. O’Shea’s honors include the National<br />
Academy of Sciences Award in Molecular Biology, a Packard Foundation Fellowship,<br />
and a Presidential Faculty Fellow Award. She is a member of the American Academy of<br />
Arts and Sciences and the National Academy of Sciences.<br />
abstract<br />
Signaling Nutrient Limitation<br />
E. O’Shea, Harvard University<br />
Howard Hughes, Medical Institute, Harvard Faculty of Arts and Sciences Center for<br />
Systems Biology, Departments of Molecular and Cellular Biology and Chemistry and<br />
Chemical Biology, Harvard University, 7 Divinity Avenue, Cambridge MA USA<br />
In conditions of nutrient limitation, cells maintain homeostasis by altering metabolomic,<br />
proteomic, and genomic profiles. Many nutrient-starvation response systems have<br />
been intensively studied in Saccharomyces cerevisiae; the cellular response to inorganic<br />
phosphate starvation is one of the best characterized. Our recent work has revealed<br />
that myo-d-inositol heptakisphosphate (IP7) is produced in response to phosphate<br />
limitation and regulates the activity of a protein kinase complex that coordinates<br />
downstream cellular responses. We are currently investigating the mechanism of<br />
action of IP7 and studying the metabolic changes that occur when cells are limited for<br />
inorganic phosphate.<br />
50 51
Full Program details<br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />
8.00-8.45 Plenary 5 Population Dynamics, Self Renewal and Culture Room: Auditorium<br />
Adaptation of Human ES cells<br />
Peter Andrews (University of Sheffield, UNITED KINGDOM)<br />
Chairperson: Jeroen Krijgsveld<br />
8.45-9.30 Plenary 6 Spatio-temporal proteomics room: Auditorium<br />
Matthias Mann (Max Plank Institute for Biochemistry, GERMANY),<br />
Jesper Olsen, Charo Robles, Nina Hubner, Johannes Graumann,<br />
Juergen Cox, Francesca Forner, Chanchal Kumar, Hubert Serve<br />
Chairperson: Ruedi Aebersold<br />
S13: EuPA Young Investigator Session room: A 11.00-12.30<br />
Chairperson: Concha Gil<br />
A Novel Approach Enabling Exploratory and Targeted Analysis with a Single LC-injection 11.05-11.22<br />
Leonie F Waanders (Max Planck Institut for Biochemistry, GERMANY), Reinaldo Almeida, Peter Bandilla,<br />
Mark H Allen, Gary A Schultz, Matthias Mann<br />
On-Line Automated In Vivo Zebrafish Phosphoproteomics 11.22-11.39<br />
Simone Lemeer (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht University, Hubrecht Institute,<br />
THE NETHERLANDS), Shabaz Mohammed, Bas van Breukelen, Jeroen den Hertog, Monique Slijper, Albert Heck<br />
DLK1 Functions in Stem Cells Studied by Quantitative Phosphoproteomics by ITRAQ and SIMAC 11.39-11.56<br />
Tine E. Thingholm (University of Southern Denmark, DENMARK), Bassem M. Abdallah, Moustapha Kassem,<br />
Ole N. Jensen<br />
Analysis of the Yeast Protein Kinase - Substrate Networks by Quantitative Phosphoproteomics 11.56-12.13<br />
Bernd Bodenmiller (Institute of Molecular Systems Biology, ETH Zurich, SWITZERLAND), Paul Shannon, Bertran<br />
Gerrits, Claudine Kraft, Mi-Youn Brusniak, Lukas Mueller, Matthias Peter, Ralph Schlapbach, Ruedi Aebersold<br />
Integrated Membrane Protein Analysis Using a Novel Combination of CY-DYE/BIOTIN Labeling 12.13-12.30<br />
Anissa Sidibe (King’s College, University of London, UNITED KINGDOM), Xiaoke Yin, Qingzhong Xiao,<br />
Anna Zampetaki, Qingbo Xu, Manuel Mayr<br />
11.00-12.30 S11 Phosphoproteomics room: Auditorium<br />
Chairpersons: Ole Jensen & Shabaz Mohammed<br />
11.00-11.30 Phosphoproteomics - Quo Vadis? Challenges and Trends in Protein Phosphorylation Analysis<br />
Ole Jensen (University of Southern Denmark, DENMARK)<br />
11.30-11.50 Optimization of Elution Conditions for Phosphopeptides Captured by Aliphatic Hydroxy Acid-Modified<br />
metal Oxide Chromatography (HAMMOC)<br />
Yutaka Kyono (Keio Univ. IAB, JAPAN), Naoyuki Sugiyama, Koshi Imami, Masaru Tomita, Yasushi Ishihama<br />
11.50-12.10 The Use of Phosphoproteomics to Discover Novel AMPK Substrates<br />
Nicholas Morrice (MRC Protein Phosphorylation Unit, UNITED KINGDOM), Franck Vandermoere, Kei Sakamoto<br />
12.10-12.30 Phosphoproteomic Analysis of Host Signaling Events Induced by Salmonella<br />
Lindsay D Rogers (The University of British Columbia, CANADA), Yuan Fang, Erin C Boyle, Leonard J Foster<br />
S14 Alternative Splicing & Protein Processing room: L 11.00-12.30<br />
Chairpersons: Kris Gevaert & Jeroen Demmers<br />
Systematic Protease Degradomics by Targeted Gel-Free Proteomics 11.00-11.30<br />
Kris Gevaert (Ghent University, BELGIUM), Petra Van Damme, Francis Impens, Veerle Vandenbussche,<br />
Kim Plasman, Kenny Helsens, Niklaas Colaert, Joël Vandekerckhove<br />
Multiplex System-Wide Discovery of Protease Substrates and Their Cleavage Sites 11.30-11.50<br />
Anna Prudova (University of British Columbia, CANADA), Ulrich auf dem Keller, Christopher Overall<br />
Alternative Splicing Detection in Large Scale Proteomics 11.50-12.10<br />
Alexandre Podtelejnikov (Proxeon A/S, DENMARK), Christian Ingrell, Morten Bern<br />
Dynamic Regulation of SUMO-2/3 Conjugates by the Ubiquitin-Proteasome System 12.10-12.30<br />
Alfred Vertegaal (Department of Molecular Cell Biology, Leiden University Medical Center, THE NETHERLANDS),<br />
Joost Schimmel, Katja Larsen, Ivan Matic, Martijn van Hagen, Jürgen Cox, Matthias Mann, Jens Andersen<br />
11.00-12.30 S12 Computational Approaches To Mine Proteomic Data room: Forum<br />
chairpersons: Pavel Pevzner & Anne-Claude Gavin<br />
11.00-11.30 MS-Dictionary: A New Approach to Peptide Identification<br />
Pavel Pevzner (University of California at San Diego, UNITED STATES), Sangtae Kim, Nitin Gupta, Nuno Bandeira<br />
11.30-11.50 A generic strategy for the comprehensive analysis of post-translation modifications<br />
Lukas Mueller (Institute of Molecular Systems Biology, SWITZERLAND), Clementine Klemm,<br />
Christine Carapito, Alex Schmidt, Bruno Domon, Ruedi Aebersold<br />
11.50-12.10 A tag chain method for identification of multiple post-translational modifications<br />
Seungjin Na (University of Seoul, KOREA), Eunok Paek, Jaeho Jeong, Kong-Joo Lee, Heejin Park<br />
12.10-12.30 Unbiased Identification of Post-Translational Modifications Using Novel Maxquant Algorithm<br />
Michael L. Nielsen (Max-Planck-Institute of Biochemistry, Department of Proteomics and Signal Transduction,<br />
GERMANY), Jürgen Cox, Tiziana Bonaldi, Michiel Vermeulen, Matthias Mann<br />
S15 Glycoproteomics room: N-N1-O1-O 11.00-12.30<br />
Chairpersons: Catherine E Costello & Peter Roepstorff<br />
Advances in Mass Spectrometry-Based Methods for Glycoprotein Analysis 11.00-11.30<br />
Catherine E Costello (Boston University School of Medicine, UNITED STATES), Marianna Budnik, Giuseppe Infusini,<br />
Yan Jiang, Elizabeth Palaima, Bo Xie, John F. Cipollo, Mark E. McComb, Peter B. O’Connor, Joseph Zaia<br />
Glycoproteomics: Applications For Stem Cell And Cancer Biomarkers 11.30-11.50<br />
Michael Pierce (Complex Carbohydrate Research Center and UGA Cancer Center, University of Georgia,<br />
UNITED STATES), S Dalton, K Moremen, M Tiemeyer, L Wells, R Orlando, K Abbott, G Alvarez-Manilla, W York<br />
Breast Milk Glycoproteome: A Defence Against Pathogenic Infection? 11.50-12.10<br />
Daniel Kolarich (Macquarie University, AUSTRALIA), Pia Hønnerup Jensen, Nicolle Packer<br />
Pilin Glycosylation, Regulated by Sll0899, is Required for Cyanobacterial Motility 12.10-12.30<br />
Young Hye Kim (Korea Basic Science Institute, KOREA), Jin Young Kim, Se-Young Kim, Jeong Hwa Lee,<br />
Ju Yeon Lee, Eun Sun JI, Young-Ho Chung, Jong Shin Yoo, Young Mok Park<br />
52 53
Full Program details<br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />
14.00-15.30 S16 Chemical Proteomics room: Auditorium<br />
chairpersons: Bernhard Kuster & Huib Ovaa<br />
14.00-14.30 Emerging Chemical Approaches to Studying the Proteome<br />
Bernhard Kuster (Technical University Munich, GERMANY)<br />
14.30-14.50 Selectivity Profiling of Lipid Kinase Inhibitors by Chemical Proteomics<br />
Thilo Werner (Cellzome AG, GERMANY), Dirk Eberhard, Giovanna Bergamini Moore, Yann Abraham,<br />
Andrew Cansfield, Kathryn Bell, Marcus Bantscheff, Gitte Neubauer<br />
14.50-15.10 Chemical Proteomics: Affinity Enrichment and Labelling of Metalloproteases<br />
Rainer Bischoff (University of Groningen, THE NETHERLANDS), Hermen Overkleeft, Henk Kauffman,<br />
Michiel Leeuwenburgh, Theo Klein, Paul Geurink<br />
15.10-15.30 Identification of Calmodulin as a Binding Protein of IHY-153, an Antiproliferative Small Molecule<br />
Hye Jin Jung (Yonsei University, KOREA), Joong Sup Shim, Jungchan Park, Hyun-Joon Ha, Jung-Ho Kim,<br />
Joong-Gon Kim, Ho Jeong Kwon<br />
S<strong>19</strong> Proteomics And Epigenetics room: L 14.00-15.30<br />
Chairpersons: Donald Hunt & Marc Timmers<br />
Innovative Mass Spectrometry Technology for the Study of Chromatin Biology 14.00-14.30<br />
Donald Hunt (University of Virginia, UNITED STATES)<br />
A proteomic screen to decipher the histone code interactome by SILAC-based proteomics 14.30-14.50<br />
Michiel Vermeulen (Max Planck Institute of Biochemistry, GERMANY), Matthias Mann<br />
The Maturation of Histone Modifications after Chromatin Assembly 14.50-15.10<br />
Axel Imhof (Center of Integrated Protein Sciences and Adolf-Butenandt Institute, Ludwig-Maximilians<br />
University of Munich, GERMANY), Annette Scharf, Theresa Barth<br />
Screen for Differential Transcription Factor Binding at Single Nucleotide Polymorphisms 15.10-15.30<br />
Falk Butter (MPI of Biochemistry, GERMANY), Michiel Vermeulen, Matthias Mann<br />
14.00-15.30 S17 Kinase- Protein Substrate Networks room: Forum<br />
Chairpersons: Michael Snyder & Pim Pijnappel<br />
14.00-14.30 Dissecting Complex Phosphorylation Regulatory Networks Using Proteomics Technologies<br />
Michael Snyder (Yale University, UNITED STATES)<br />
14.30-14.50 Dynamic Changes in the ERK1 Interactome Determine Cell Fate Decisions<br />
Alex von Kriegsheim (Beatson Institute for Cancer Research, UNITED KINGDOM), Daniela Baiocchi,<br />
Willy Bienvenut, Andrew Pitt, Walter Kolch<br />
14.50-15.10 Identification of Plk1 Specific Phosphorylation Sites on Spindle Proteins<br />
Anna Santamaria (MPI of Biochemistry, Dept. of Cell Biology, GERMANY), Bin Wang, Rainer Malik,<br />
Sabine Elowe, Erich Nigg, Roman Koerner<br />
15.10-15.30 Casting the Net for Kinases: Systematic Discovery of In Vivo Phosphorylation Networks<br />
Rune Linding (Institute of Cancer Research, UNITED KINGDOM)<br />
S20 Proteomics Of The Nervous Systems room: N-N1-O1-O 14.00-15.30<br />
Chairperson: Jyoti Choudhary<br />
Synapse Proteomics 14.00-14.30<br />
Jyoti Choudhary (Wellcome Trust Sanger Institute, UNITED KINGDOM)<br />
Quantitative Synaptic Proteomics in a Mouse Model for the Fragile X Syndrome 14.30-14.50<br />
Ka wan Li (Department of Molecular and Cellular Neurobiology, VU University Amsterdam, THE NETHERLANDS),<br />
Patricia Klemmer, Oleg I. Klychnikov, Carl D. Holmgren, Huibert D. Mansvelder, <strong>August</strong> B. Smit<br />
The Effects of UBB+1 on the Brain Proteome in a Transgenic Mouse Model 14.50-15.10<br />
Caroline May (Medizinisches-Proteom Center, GERMANY), Thomas Schulenborg, Fred W. van Leeuwen,<br />
Martin Irmler, Rohan de Silva, Walter Schubert, Johannes Beckers, Helmut E. Meyer, Katrin Marcus<br />
The Glioma Cell Surface Signal Transduction Network 15.10-15.30<br />
Thomas Bock (NCCR Neuro Center for Proteomics, Institute of Molecular Systems Biology, Swiss Federal Institute of<br />
Technology (ETH), SWITZERLAND), Andreas Hofmann, Damaris Bausch-Fluck, Bernd Wollscheid<br />
14.00-15.30 S18 Proteomics Of Macromolecular Complexes Room: A<br />
Chairperson: Brian Chait<br />
14.00-14.30 Proteomic Approaches for Analyzing Complex Biological Machines<br />
Brian Chait (The Rockefeller University, University of California, UNITED STATES), F Alber, S Dokudovskaya,<br />
L Veenhoff, W Zhang, D Devos, O Karni-Schmidt, A Suprapto, R Williams, A Sali, MP Rout<br />
14.30-14.50 Novel Chromatin Immunopurification (mCHIP) Approaches for the Mapping of Protein Interactions.<br />
Daniel Figeys (OISB/University of Ottawa, CANADA), Mohamed Abu-Farha, Jean-Philippe Lambert<br />
14.50-15.10 An Integrated Experimental Workflow to Increase Throughput and Data Robustness for Global Analysis<br />
of Human Protein Interaction Networks<br />
Timo Glatter (ETH Zürich, SWITZERLAND)<br />
Plenary 7 The Social Network Of A Cell: Room: Auditorium 16.00-16.45<br />
dynamic Protein Interactions<br />
Anne-Claude Gavin (EMBL Heidelberg, GERMANY)<br />
Chairperson: Richard Simpson<br />
Plenary 8 SIGNALING NUTRIENT limitation room: Auditorium 16.45-17.30<br />
Erin O’Shea (Harvard University, Howard Hughes Medical Institute, UNITED STATES)<br />
chairperson: John Yates<br />
15.10-15.30 Characterizing a Minimal Molecular Machinery<br />
Sebastian Kühner (EMBL Heidelberg, GERMANY)<br />
54 55
Publishing in Proteomics<br />
20.00 - 22.00<br />
Chair: Peipei Ping<br />
Program to be announced.<br />
evening sessions<br />
Challenges/Solutions for Implementing Proteomics into<br />
Clinical Practice - An Open Forum Discussion<br />
20.00 - 22.00<br />
Moderator: Salvatore Sechi, NIDDK, National Institutes of Health, USA<br />
room: A<br />
room: B<br />
Leaders in the field including Denis Hochstrasser, Geneva University and University<br />
Hospital, Daniel W. Chan, Johns Hopkins Medical Institutions, and Christer Wingren,<br />
Lund University will open the discussion addressing the following key questions:<br />
What are the regulatory issues and barriers in the approval/use of biomarkers<br />
as diagnostic and what can we do about it?<br />
What is needed for moving proteomics assays into clinical practice?<br />
How can we foster interaction/collaboration/partnership between clinicians and<br />
basic scientists and the private sector?<br />
Today most diagnostic assays use a single analyte as biomarker or surrogate<br />
endpoint what are the barrier for implementing multi-analyte diagnostic?<br />
Regulatory agencies, private companies, funding agencies, clinicians and proteomics<br />
experts are invited to participate in the discussion and/or present their perspective<br />
in a concise way (no more than 1 slide / 3-5 minutes).<br />
Whether a test is clearly described;<br />
If the true presence or absence of disease can be established for all individuals;<br />
Whether the spectrum of patients with and without disease is adequate;<br />
Whether the assessment of test and disease status is conducted in an unbiased<br />
manner; and<br />
If the test performance is summarized by the important terms of sensitivity and<br />
specificity.<br />
Speakers:<br />
Concept of Validation: Nuts and Bolts of Good Proteomic Study<br />
Sudhir Srivstava, National Cancer Institute<br />
Biomarkers and FDA Regulation of In Vitro Diagnostic Devices<br />
Robert Becker, Food and Drug Administration<br />
Mass Spectrometry-based Platforms for Biomarker Discovery and Verification<br />
Daniel Liebler, Vanderbilt School of Medicine<br />
Reproducibility Testing of Gel-based Proteomics<br />
Hans Voshol, Novartis Institutes for Biomedical Research<br />
Validation in the eyes of a Basic Scientist<br />
John Bergeron<br />
Validation in the eyes of Clinical Scientist<br />
Mathias Uhlén<br />
Summary<br />
Sudhir Srivastava<br />
Workshop on Proteomics Validation<br />
room: L<br />
20.00 - 22.30<br />
What Does Proteomics Validation Mean to the Users, Regulators and Public Health<br />
Professionals?<br />
Chair: Sudhir Srivastava<br />
Objective: The term ‘validation’ is grossly misused. It means different things to<br />
different people, and often not tied with the requirements that are expected by<br />
the regulatory and clinical community. The term has taken a new meaning in light of<br />
high throughput, high dimensional technologies, like proteomics where the number of<br />
features (biomarkers) are much more higher than the number of samples and this<br />
often leads to the over-fitting of the data. This has raised an alarm in the minds<br />
of regulators and clinicians due the potentially high rates of false positive cases.<br />
This symposium will invite clinicians, regulators and basic scientists to discuss their<br />
experience and provide guidance to the proteomic community. The symposium will build<br />
on the concept of validation asks:<br />
56 57
Making the most<br />
of genomics<br />
The Netherlands Genomics Initiative (NGI) aims to get the<br />
best from genomics by providing excellence in genomics.<br />
NGI was established by the Dutch government in 2002 and<br />
is now entering its second phase: 2008-2012. The overall<br />
objective of NGI is to ensure that society and economy<br />
benefit from the breakthroughs enabled by genomics in<br />
important fields like health, agro-food, sustainability,<br />
enabling technologies and society.<br />
Forensic<br />
Genomics Consortium<br />
Netherlands<br />
Netherlands Consortium<br />
for Systems Biology<br />
Celiac Disease Consortium<br />
Netherlands<br />
Metabolomics Centre<br />
Netherlands Consortium<br />
for Healthy Ageing<br />
Centre for Medical<br />
Systems Biology<br />
Kluyver Centre for Genomics<br />
of Industrial Fermentation<br />
16 NGI Genomics Centres in the Netherlands<br />
health | agro-food | sustainability | enabling technologies | society<br />
VIRGO Consortium<br />
Ecogenomics<br />
Consortium<br />
Cancer Genomics Centre<br />
Nutrigenomics<br />
Consortium<br />
Centre for BioSystems<br />
Genomics<br />
Netherlands<br />
Bioinformatics Centre<br />
Centre for Society<br />
and Genomics<br />
Netherlands<br />
Toxicogenomics Centre<br />
Enabling Technologies<br />
Tools to analyse, probe<br />
and explore<br />
Unravelling the complex network of biological<br />
processes that constitute life in all its forms – the<br />
core of modern life sciences research – requires<br />
not only an inquisitive mindset, but also a battery<br />
of high-grade technology platforms.<br />
NGI enables probing into the fascinating world<br />
of biology by initiating, organising and funding<br />
a number of technology centres that are<br />
accessible to the Dutch and international life<br />
sciences community. These centres work on their<br />
own research programmes, develop and<br />
disseminate new technologies, tools and<br />
methods, offer technical support and serve as<br />
training centres for scientists and technicians.<br />
Bioinformatics, proteomics, metabolomics,<br />
toxicogenomics and systems biology are the focus<br />
of NGI’s efforts in technology development.<br />
Meet us at<br />
the HUPO<br />
Exhibition<br />
Booth 9<br />
P.O. Box 93035 – 2509 A A The Hague – The Netherlands | T +31 70 344 0672 | F +31 70 344 0632 | E info@genomics.nl<br />
Be part of the thriving NGI genomics community | visit www.genomics.nl /jobs<br />
Wednesday 20 <strong>August</strong> 2008<br />
Room M Room B Room CD Room EF<br />
Room<br />
N-N1-O1-O<br />
Room Forum Room A Room L<br />
Room<br />
Auditorium<br />
Forum Ground<br />
Floor<br />
location <br />
time <br />
Speaker Ready<br />
Room<br />
Registration &<br />
Information<br />
whole day<br />
Corporate Workshop<br />
Thermo Scientific<br />
Corporate Workshop GE<br />
Healthcare<br />
Corporate Workshop<br />
Rosetta Bio<strong>software</strong><br />
07.00 - 07.50<br />
08.00 - 08.45 Sung-Hou Kim<br />
08.45 - 09.30 John Yates<br />
09.30 - 11.00 Break & Posters in Exhibition Hall 10<br />
S25<br />
Structural<br />
Proteomics<br />
S24<br />
Assembling the parts:<br />
Whole Cell Modelling /<br />
Biomarkers 1<br />
S23<br />
Array Based<br />
Proteomics<br />
S22<br />
Quantification<br />
S21<br />
Integration and<br />
storage of<br />
proteomics data<br />
11.00 - 12.30<br />
Corporate Workshop<br />
Invitrogen<br />
Corporate Workshop<br />
Bio-Rad Laboratories<br />
Corporate Workshop<br />
Waters<br />
12.30 - 14.00 Lunch, Poster Session & Exhibition in Exhibition Hall 10<br />
S30<br />
Proteome biology of<br />
infectous diseases<br />
S29<br />
Single cell imaging/<br />
HUPO Young<br />
Investigator Awards<br />
S28<br />
Biomarkers 2<br />
S27<br />
Cancer related signaling<br />
S26<br />
Stem cell<br />
proteome biology<br />
14.00 - 15.30<br />
15.30 - 16.00 Break & Posters in Exhibition Hall 10<br />
HUPO 2008<br />
Award Session<br />
16.00 - 17.30<br />
Announcement HUPO<br />
2009 & Closing<br />
17.30 - 18.00<br />
<strong>19</strong>.00 - 23.00 Congress Dinner<br />
Legend: = Social <strong>event</strong> = Plenary session = Corporate Workshop = Symposium<br />
= Initiative = Other meeting<br />
58 59
Plenary Speakers Wednesday<br />
Sung-Hou Kim<br />
John Yates<br />
BIOGRAPHY<br />
Sung-Hou Kim is a professor in the Department of Chemistry, University of California,<br />
Berkeley, CA (UCB), and a Senior Faculty Scientist at Lawrence Berkeley National<br />
Laboratory (LBNL), Berkeley, CA. He currently serves as the Director of the Berkeley<br />
Structural Genomics Center, LBNL, and the Head of the Structural Biology Department,<br />
Physical Biosciences Division, LBNL. He is a member of the U. S. National Academy of<br />
Sciences, and a fellow of the American Academy of Arts and Sciences. His research<br />
interest has been in Structural Biology, Structural Genomics, Computational Genomics,<br />
and Drug Discovery.<br />
Abstract<br />
Demography and Phylogeny of Structural and Sequence Proteomes<br />
S.-H. Kim, S.-R. Jun, G.A. Wu, and G.E. Sims, Univ. of California and Lawrence Berkeley<br />
National Laboratory, Berkeley CA 94720 USA<br />
A large number of 3-D structures of proteins became available by the recent<br />
development of structure determination technology during the last two decades. There<br />
are a few “minimal organisms,” for which over 95% of the soluble, globular proteins<br />
may now be assigned their structural folds. Near-complete structural proteome of one<br />
minimal organism is analyzed as they relate to protein functions and fold usage among<br />
functional categories. The structural proteome of the organism is then “mapped”<br />
on the protein structure universe, a collection of all known protein structures. This<br />
“mapping” reveals features that may be interpretable in terms of evolution of protein<br />
structure and function.<br />
Similarly, a large number of whole genome sequences and individual gene sequences<br />
became available by the explosive development of sequencing technology during the<br />
last two decades. Currently, most comparison methods rely on the multiple sequence<br />
alignment of one or more common genes among the population examined, and do not<br />
utilize the whole genome sequences. We have developed alignment-free methods to<br />
compare and organize whole genome sequences (coding and non-coding regions) or<br />
whole genome coding sequences (sequence proteomes). The methods allow us to map<br />
“demography” of organisms represented by whole genome sequences or whole genome<br />
coding region sequences. Such mapping can provide a global view of distribution and<br />
relationship among the demographic groups of organisms, and possibly their evolution.<br />
Funded by NIH (P50 GM62412)<br />
BIOGRAPHY<br />
John Yates received his Ph.D. in Chemistry at the University of Virginia under Professor<br />
Donald Hun and is now a Professor in the Department of Chemical Physiology at The<br />
Scripps Research Institute. His research interests include development of integrated<br />
methods for tandem mass spectrometry analysis of protein mixtures, bioinformatics<br />
using mass spectrometry data, and proteomics.<br />
Abstract<br />
Driving Biological Discovery Using Quantitative Mass Spectrometry<br />
John R. Yates<br />
Department of Chemical Physiology, 10550 North Torrey Pines Road, SR11, The Scripps<br />
Research Institute, LaJolla, CA 92037 USA<br />
A component to understanding biological processes involves identifying the proteins<br />
expressed in cells as well as their modifications and the dynamics of processes. Several<br />
major technologies, but especially mass spectrometry, have benefited from large-scale<br />
genome sequencing of organisms. The sequence data produced by these efforts can<br />
be used to interpret mass spectrometry data of proteins and thus enables rapid and<br />
large-scale analysis of protein data from experiments. Advances in multi-dimensional<br />
separations as well as mass spectrometry have improved the scale of experiments<br />
for protein identification. This has improved the analysis of protein complexes, and<br />
more complicated protein mixtures. Quantitative mass spectrometry can be used to<br />
study biological processes such as development or the effects of gene mutations on<br />
pathways. Methods to improve the sample preparation, separation of peptides and<br />
analysis of the data will be described as well applications of shotgun proteomics to the<br />
study biological processes.<br />
60 61
Full Program details<br />
Wednesday 20 <strong>August</strong><br />
8.00-8.45 Plenary 9 Demography and Phylogeny of Structural Room: Auditorium<br />
and Sequence Proteomes<br />
Sung-Hou Kim (University of California Berkeley, Lawrence Berkeley National<br />
laboratory, UNITED STATES), Se-Ran Jun, G Albert Wu, Gregory E. Sims<br />
Chairperson: Brian Chait<br />
8.45-9.30 Plenary 10 Driving Biological Discovery Using Quantitative Room: Auditorium<br />
Mass Spectrometry<br />
John Yates (The Scripps Research Institute, UNITED STATES)<br />
Chairperson: Don Hunt<br />
S23 Array Based Proteomics room: A 11.00-12.30<br />
Chairperson: Joshua LaBaer<br />
Functional Proteomics for Biomarker and Target Discovery 11.00-11.30<br />
Joshua LaBaer (Harvard Medical School, UNITED STATES)<br />
Proteome Microarray Analysis of the Antibody Response to Infectious Diseases 11.30-11.50<br />
Robert Ulrich (Army Medical Research Institute of Infectious Diseases, UNITED STATES), Sarah Keasey,<br />
James Meagan, Alexander Tikhonov, Barry Schweitzer<br />
PDMS-Based Protein Chips for Proteomics 11.50-12.10<br />
Wang-Chou Sung (National Cheng kung University, TAIWAN), Makamba Honest, Shu-Hui Chen<br />
Antibody Microarrays – A Way to Define Predictive Biomarker Signatures in Cancer 12.10-12.30<br />
Carl Borrebaeck (Lund University, SWEDEN)<br />
11.00-12.30 S21 Integration And Storage Of Proteomics Data room: Auditorium<br />
Chairpersons: Rolf Apweiler & Bas van Breukelen<br />
11.00-11.30 Bioinformatics Infrastructure for Proteomics: Status of Database and Standards Development<br />
Rolf Apweiler (EMBL-EBI, UNITED KINGDOM)<br />
11.30-11.50 Design and Implementations of the New PSI Mass Spectrometer Output File Standard: mzML 1.0<br />
Eric W. Deutsch (Institute for Systems Biology, United States), Lennart Martens, Joshua Tasman, Jim<br />
Shofstahl, Darren Kessner, Matthew Chambers, Fredrik Levander, Puneet Souda, Luisa Montecchi-Palazzi,<br />
Henning Hermjakob, Pierre Alain Binz<br />
11.50-12.10 The PRIDE Database: Better, Faster, Stronger<br />
Richard Cote (European Bioinformatics Institute, UNITED KINGDOM), Phil Jones, Lennart Martens,<br />
Juan Antonio Vizcaino, Henning Hermjakob<br />
12.10-12.30 ProHits - A Complete LIMS System For Functional Proteomics<br />
Frank Liu (Centre for Systems Biology, Samuel Lunenfeld Research Institute, CANADA), Jian Ping Zhang,<br />
Brett Larsen, Ashton Breitkreutz, Zhen-Yuan Lin, Jim Woodgett, Tony Pawson, Jeff Wrana,<br />
Anne-Claude Gingras, Mike Tyers<br />
S24 Assembling The Parts: Whole Cell Modelling + Biomarkers 1 room: L 11.00-12.30<br />
Chairperson: Rob Russell<br />
New Peptides Mediating Interaction Networks: From Two-hybrid Networks to 3D Structure 11.00-11.30<br />
Rob Russell (EMBL, GERMANY)<br />
Formlin-fixed Paraffin Embedded (FFPE) Clinical Proteome Initiative of Lung Cancer 11.30-11.50<br />
Toshihide Nishimura (Tokyo Medical University, JAPAN), Masaharu Nomura, Sayaka Mikami, Hiroko Endo,<br />
Yasuhiko Bando, Ryotaro Nishiyama, Kiyonaga Fujii, Sumie Ando, Hiroko Hamazaki, Harubumi Kato<br />
Naturally Occurring Urinary Peptides for Differential Diagnosis of Chronic Kedney Disease 12.10-12.30<br />
Harald Mischak (Mosaiques-Diagnostics, GERMANY), Kasper Rossing, Jan Novak, Bruce A. Julian,<br />
Moritz Frommberger, Eric Schiffer, Philippe Schmitt-Kopplin<br />
Oligosaccharide Microarrays and Prospects for Deciphering the Glyco-code 11.50-12.10<br />
Ten Feizi (Imperial College, united kingdom)<br />
11.00-12.30 S22 Quantification Room: Forum<br />
Chairpersons: Shu-Hui Chen & Chris de Koster<br />
11.00-11.30 Quantitative Nano-Proteomics Using Stable Isotope Dimethyl Labeling - Resolving Protein Complexes<br />
related to Estrogen Action<br />
Shu-Hui Chen (National Cheng Kung University, TAIWAN)<br />
11.30-11.50 Triplex Stable Isotope Dimethyl Labeling and its Application in Chemical Proteomics<br />
Paul Boersema (Utrecht University, THE NETHERLANDS), Thin Thin Aye, Toon van Veen, Albert Heck,<br />
Shabaz Mohammed<br />
11.50-12.10 MRM Analysis of Tumor Homogenates for Absolute Quantification of Potential Biomarkers<br />
Leroi DeSouza (CRMS York University, CANADA), Marjorie Minkoff, Terence Colgan, Alexander Romaschin,<br />
KW Michael Siu<br />
12.10-12.30 Proteome-wide Accurate Label-free Quantitation of Mammalian Cells<br />
Juergen Cox (Max Planck Institute of Biochemistry, GERMANY), Christian Luber, Matthias Mann<br />
S25 Structural Proteomics room: N-N1-O1-O 11.00-12.30<br />
Chairpersons: Cheryl Arrowsmith & Rolf Boelens<br />
Integrating Structural Genomics and Chemical Genomics for Biology and Medicine 11.00-11.30<br />
Cheryl Arrowsmith (Structural Genomics Consortium, CANADA)<br />
Visual Proteomics of the Human Pathogen Leptospira Interrogans 11.30-11.50<br />
Martin Beck (Swiss Federal Institute of Technology, SWITZERLAND), Johan Malmstroem, Vinzenz Lange,<br />
Alexander Schmidt, Eric Deutsch, Ruedi Aebersold<br />
Interactome and Interface Protocol - 2 nd Generation Strategy for Topology Mapping of Protein Complexes 11.50-12.10<br />
Gerold Schmitt-Ulms (University of Toronto, CANADA)<br />
Intramolecular Interactions Within Voltage/Ca2+ Gated K+ Channels: Structure/Function Implications 12.10-12.30<br />
Sarah Warburton (University of California Los Angeles, UNITED STATES), Taleh Yusifov, Thomas Vondriska,<br />
Riccardo Olcese<br />
62 63
Full Program details<br />
Wednesday 20 <strong>August</strong><br />
14.00-15.30 S26 Stem Cell Proteome Biology room: Auditorium<br />
Chairperson: Jeroen Krijgsveld<br />
14.00-14.30 Quantitative Phospho-proteomics of Human Embryonic Stem Cell Differentiation<br />
Jeroen Krijgsveld (Utrecht University, THE NETHERLANDS), Javier Muñoz, Dennis Van Hoof, Martijn Pinkse,<br />
Stefan Braam, Bas van Breukelen, Christine Mummery, Albert Heck<br />
14.30-14.50 Tracking Patterns of Post-translational Modification on Histone H4 During Differentiation of Human ES Cells<br />
Justin Brumbaugh (University of Wisconsin, UNITED STATES)<br />
14.50-15.10 Metabolic Labeling and Click Chemistry Detection of Stem Cell Markers<br />
Brian Agnew (Molecular Probes-Invitrogen, UNITED STATES), Courtenay Hart, Mahbod Hajivandi,<br />
Marshall Pope, Lucas Chase<br />
15.10-15.30 Quantitative Analysis of the Mesenchymal Stem Cell Secretome during Osteogenesis<br />
Lars Kristensen (University of Southern Denmark, DENMARK), Moustapha Kassem, Jens Andersen<br />
14.00-15.30 S27 Cancer Related Signaling room: Forum<br />
Chairpersons: Connie Jimenez & Monique Slijper<br />
14.00-14.30 Proteomics Targeted to Sub-cellular Compartments and Secretomes for Discovery of Signaling<br />
pathways in Colorectal Cancer<br />
Connie Jimenez (VU University Medical Center, THE NETHERLANDS), Jakob Albrethsen, Remond Fijneman,<br />
Jaco Knol, Sander Piersma, Meike de Wit, Sandra Mongera, Beatriz Carvalho, Gerrit Meijer<br />
14.30-14.50 Addressing the Angiogenic Switch by Studying Tumor-host Interactions in a Model of Glioma<br />
Uros Rajcevic (NorLux Neuro-oncology, CRP-Sante, LUXEMBOURG), Jaco C. Knol, Maarten Loos, KaWan Li,<br />
Oleg Klychnikov, Rolf Bjerkvig, Thang V. Pham, Kjell Petersen, Connie R. Jimenez, Simone P. Niclou<br />
14.50-15.10 Multiplex Substrate Degradomics of Matrix Metalloproteinases in Breast Carcinogenesis<br />
Ulrich auf dem Keller (Centre for Blood Research, University of British Columbia, CANADA), Anna Prudova,<br />
Yuanmei Lou, Shoukat Dedhar, Christopher Overall<br />
15.10-15.30 Phosphoproteomics Analysis Reveals Divergent Signaling for Oncogenic FLT3 Mutants<br />
Yi Zhang (Dana-Farber Cancer Institute, UNITED STATES), Manor Askenazi, Chance Luckey, Jarrod Marto<br />
14.00-15.30 S28 Biomarkers 2 Room: A<br />
Chairperson: Richard Simpson<br />
14.00-14.30 Secretome-based Proteomic Strategies for Uncovering New Biomarkers for Colorectal Cancer<br />
Richard Simpson (Ludwig Institute for Cancer Research & Walter and Eliza Hall Institute of Medical Research,<br />
AUSTRALIA), Justin Lim, Eugene Kapp, Bow Tauro, Thomas Barnes, Oliver Bernhard, Robert Moritz<br />
14.30-14.50 Cell-based Proteome Analysis: The First Stage in the Pipeline for Biomarker Discovery<br />
Barbara Sitek (Medizinisches Proteom-Center, Ruhr Universität Bochum, GERMANY), Gereon Poschmann,<br />
Corinna Henkel, Bence Sipos, Oliver Vonend, Helmut E. Meyer, Kai Stühler<br />
14.50-15.10 The Use of Plasma Proteomics to Study Disease Pathogenesis<br />
William Hancock (Northeastern University, UNITED STATES), Marina Hincapie, Majlinda Kullolli,<br />
Tatiana Plavina<br />
15.10-15.30 Shotgun Proteomics of Human Gastric Juice<br />
Maxey Ching Ming Chung (Department of Biochemistry, Yong Loo Lin School of Medicine, Department of<br />
Biological Sciences, Faculty of Science, National University of Singapore, SINGAPORE), Cynthia R.M.Y. Liang,<br />
Qingsong Lin, Sandra Tan, Teck Kwang Lim, Yi Liu, Khay Guan Yeoh, Jimmy So, Choy Leong Hew<br />
S29 Single Cell Imaging + HUPO YIP room: L 14.00-15.30<br />
Chairpersons: Philippe Bastiaens & John Yates<br />
Imaging Reaction Dynamics For Cellular Systems Biology 14.00-14.30<br />
Philippe Bastiaens (MPI for Molecular Physiology, Dept. of Systemic Cell Biology, GERMANY)<br />
A Systems View of the Cell Cycle by Parallel Quantitation of Proteome and Phosphoproteome 14.30-14.50<br />
Jesper V. Olsen (Max-Planck-Institute for Biochemistry, GERMANY), Michiel Vermeulen, Anna Santamaria,<br />
Chanchal Kumar, Florian Gnad, Jürgen Cox, Erich Nigg, Matthias Mann<br />
Exploring Different Enzymes to Allow Facile Peptide Sequencing by ETD 14.50-15.10<br />
Shabaz Mohammed (Biomolecular Mass Spectrometry and Proteomics Group, Bijvoet Center for Biomolecular<br />
Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, THE NETHERLANDS),<br />
Nadia Taouatas, Kristina Lorenzen, Madalina Drugan, Alessandro Vannini, Patrick Cramer, Albert Heck<br />
New Targets of Snake Venom Metalloproteinases Revealed by Proteomic Approaches 15.10-15.30<br />
Adriana Paes Leme (Instituto Butantan, BRAZIL), Marina Assakura, Antonio Camargo, Nicholas Sherman,<br />
Jay Fox, Solange Serrano<br />
S30 Proteome Biology Of Infectious Diseases room: N-N1-O1-O 14.00-15.30<br />
Chairpersons: Young-Ki Paik & Paul Hensbergen<br />
Proteome Biology of Candida albicans Infection and Action Mechanism of Antifungal Agents 14.00-14.10<br />
Young-Ki Paik (Yonsei Proteome Research Center, Yonsei University, KOREA), Hyoung-Joo Lee,<br />
Jong Shin Yoo, Ki-Young Kim, Yu-Kyong Shin<br />
Proteomics Applied to the Study of Hepatitis C Virus Pathogenesis 14.10-14.30<br />
Romain Parent (Fred Hutchinson Cancer Research Center, UNITED STATES), Sufen Shang, Neha Lohia,<br />
Laura Beretta<br />
Proteolytic Processing of the Campylobacter Adherence Factor (CadF) in Campylobacter Jejuni 14.30-14.50<br />
Stuart Cordwell (University of Sydney, AUSTRALIA), Nichollas Scott<br />
Proteomics of Influenza Virus and Vaccine 14.50-15.10<br />
Michail Alterman (FDA/CBER/OCTGT/TVBB, UNITED STATES), Melkamu Getie-Kebtie, Maryna Eichelberger<br />
Phosphoproteome of Primary Human Host Cells Infected with Yersinia pestis 15.10-15.30<br />
Ramin Hakami (USAMRIID, UNITED STATES)<br />
Eupa and HUPO Awards session room: Auditorium 16.00-17.30<br />
Introduction by Albert Heck 16.00-16.05<br />
Amsterdam Young Scientist Award 16.05-16.15<br />
Awardee: To Be Announced (TBA)<br />
EuPA Senior Scientist Award in Proteomic Sciences 16.15-16.20<br />
Elsevier representative: Adriaan Klinkenberg · Eupa representative: EuPA President · Awardee: Stellan Hjerten<br />
Announcement Eupa Ph.D. Award 16.20-16.25<br />
Elsevier representative: Adriaan Klinkenberg · Eupa YIP representative: Concha Gil<br />
Awardees: TBA, selected after their presentation<br />
HUPO YIP Prize announcement 16.25-16.30<br />
HUPO representative: Pierre Legrain · HUPO YIP representative: John Yates<br />
Awardees: Jesper Olsen, Shabaz Mohammed, Adriana Paes Leme<br />
HUPO Discovery in Proteomic Sciences award 16.30-16.35<br />
HUPO representative: Pierre Legrain · Awardee: Catherine Costello<br />
HUPO Distinguished Service Award 16.35-16.40<br />
HUPO representative: Pierre Legrain and Rolf Apweiler · Awardee: Richard Simpson<br />
HUPO Distinguished Achievement Award 16.40-17.00<br />
JPR Representative: TBA · HUPO representative: Pierre Legrain and Rolf Apweiler · Awardee: Denis Hochstrasser<br />
HUPO Distinguished Achievement Award 17.00-17.30<br />
JPR Representative: TBA · HUPO representative: Pierre Legrain and Rolf Apweiler · Awardee: Matthias Mann<br />
64 65
Poster topics<br />
Monday 18 <strong>August</strong><br />
wednesday 20 <strong>August</strong><br />
Topics<br />
Poster Numbers<br />
Topics<br />
Poster Numbers<br />
Biomarkers I<br />
P-MON-001 - P-MON-126<br />
Array Based Proteomics<br />
P-WED-001 - P-WED-028<br />
Innovation In Peptide & Protein Seperation<br />
Technologies<br />
Molecular Mass Imaging<br />
Organelle and biological membranes<br />
Proteomics<br />
Quantification I<br />
Reagents for proteomics<br />
Standards for Clinical Proteomics<br />
Stem cell proteome biology<br />
Structural Proteomics<br />
P-MON-127 - P-MON-186<br />
P-MON-187 - P-MON-204<br />
P-MON-205 - P-MON-267<br />
P-MON-268 - P-MON-303<br />
P-MON-304 - P-MON-318<br />
P-MON-3<strong>19</strong> - P-MON-330<br />
P-MON-331 - P-MON-353<br />
P-MON-354 - P-MON-370<br />
Biomarkers III<br />
Cardiovascular Proteome Biology<br />
Integration and storage of proteomics data<br />
Kinase-protein substrate networks<br />
Proteome biology of infectious diseases<br />
Proteomics and epigenetics<br />
Proteomics of the nervous systems<br />
Quantification II<br />
Other<br />
P-WED-029 - P-WED-101<br />
P-WED-102 - P-WED-143<br />
P-WED-144 - P-WED-166<br />
P-WED-167 - P-WED-171<br />
P-WED-172 - P-WED-208<br />
P-WED-209 - P-WED-217<br />
P-WED-218 - P-WED-251<br />
P-WED-252 - P-WED-291<br />
P-WED-292 - P-WED-355<br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />
Topics<br />
Alternative splicing & protein processing<br />
Biomarkers II<br />
Poster Numbers<br />
P-TUE-001 - P-TUE-014<br />
P-TUE-015 - P-TUE-040<br />
C. elegans and Drosophila P-TUE-041 - P-TUE-048<br />
Cancer related signaling<br />
Chemical Proteomics<br />
Computational approaches to mine<br />
proteomic data<br />
Glycoproteomics<br />
Mass Spectrometric Innovations<br />
Phosphoproteomics<br />
Plant proteomics<br />
Proteomics of Macromolecular Complexes<br />
Yeast proteomics; sparks for new biology<br />
P-TUE-049 - P-TUE-110<br />
P-TUE-111 - P-TUE-135<br />
P-TUE-136 - P-TUE-<strong>19</strong>3<br />
P-TUE-<strong>19</strong>4 - P-TUE-225<br />
P-TUE-226 - P-TUE-250<br />
P-TUE-251 - P-TUE-306<br />
P-TUE-307 - P-TUE-322<br />
P-TUE-323 - P-TUE-362<br />
P-TUE-363 - P-TUE-370<br />
66 67
Poster Listing<br />
Monday 18 august<br />
Biomarkers I<br />
P-MON-001<br />
P-MON-002<br />
P-MON-003<br />
P-MON-004<br />
Targeting Serum Glycoprotein Cancer Biomarkers With Click Chemistry<br />
Courtenay Hart (Molecular Probes-Invitrogen, UNITED STATES), Brian Agnew,<br />
Tamara Nyberg, Mahbod Hajivandi, Marshall Pope, Rajkumar Lakshmanaswamy<br />
Glycoproteome Analysis In Human Plasma Using Multi-Lectin Affinity Column And<br />
Lc-Ms/Ms For The Discovery Of Potential Diabetic Nephropathy Biomarkers<br />
Jung-Mo Ahn (Department of Biochemistry, School of Dentistry Kyungpook National<br />
University, KOREA), Byung-kyu Kim, Ji-hyun Lee, Hye-sim Cho, In-Kyu Lee, Je-Yoel Cho<br />
Evaluation Of Correlation Between Cyfra 21-1 And Cea With Telomerase Activity<br />
In Lung Cancer Patients And Healthy Controls<br />
Behrang Alani (Department of Physiology and Pharmacology, School of Medicine,<br />
Kashan University, IRAN), Khalil Ansarin, Massood Nazemieh, Mahdi Noureddini,<br />
Abbas Mohajeri, Amir Reza Amir Hejri<br />
Comparative Proteomic Study Of The Human Erythrocyte ‘Ghost’ Microsomal<br />
Fraction In Copd<br />
Bruno Alexandre (Laboratorio Proteomica, Dept. Genetica Humana INSA, I.P.,<br />
PORTUGAL / Laboratory of Proteomics and Analytical Technologies, SAIC-Frederick<br />
Inc., National Cancer Institute at Frederick, USA), Nuno Charro, Antonio Bugalho de<br />
Almeida, Timothy Veenstra, Josip Blonder, Deborah Penque<br />
P-MON-011<br />
P-MON-012<br />
P-MON-013<br />
P-MON-014<br />
P-MON-015<br />
P-MON-016<br />
Identification Of Protein Expressed By Aortic Stenosis Valves In The Search For<br />
Novel Biomarkers<br />
Felix Gil-Dones (Laboratorio de Fisiopatología Vascular. Hospital Nacional de Parapléjicos.<br />
SESCAM., SPAIN), Tatiana Martin-Rojas, Natacha Diaz-Prieto, Luis F. Lopez-Almodovar,<br />
Fernando de la Cuesta, Gloria Alvarez-llamas, Fernando Vivanco, Luis R. Padial,<br />
Maria G. Barderas<br />
Biomarkers For Tse Disease:- Seldi-Tof Approach<br />
Janice Barr (Roslin Institute / NPU, UNITED KINGDOM), Michael Watson, Nathan<br />
Harris, James W. Ironside, Mark W. Head, Rona Barron<br />
A Proteomic Approach To The Identification Of Stress Biomarkers For Bovine<br />
And Porcine Livestock<br />
Anna Bassols (Universitat Autonoma de Barcelona, SPAIN), Anna Marco, Yolanda Saco,<br />
Jose Luis Ruiz de la Torre, Alex Bach<br />
Development Of Specific Silicon Chips And Magnetic Nanobeads For Low And No<br />
Invasive Brain “Micro-Nanoproteomic”<br />
François Berger (INSERM U 836 Brain Nanomedicine Group, FRANCE), Ali Bouamrani,<br />
Affif zacaria, Claire Ramus, David Ratel, Maryline Cosnier, Patrice Caillat, Stephan Chabardes<br />
Ranking Of Soluble-Secreted Proteins (Rssp): A Biomarker Strategy For Colon Cancer<br />
Oliver Bernhard (Ludwig Institute for Cancer Research / The Walter and Eliza Hall<br />
Institute, AUSTRALIA), Richard Simpson<br />
Prenatal Bisphenol - A Exposure Alters The Mammary Gland Proteome In<br />
Prepubertal And Adult Rats<br />
Angela Betancourt (University of Alabama at Birmingham, UNITED STATES), Coral<br />
Lamartiniere<br />
P-MON-005<br />
P-MON-006<br />
P-MON-007<br />
P-MON-008<br />
P-MON-009<br />
Biomarkers For Hypertension - Relationship Between Body Fluids And Tissue<br />
Heather Allingham (Glasgow University, UNITED KINGDOM), Richard Goodwin, Martin<br />
McBride, Carsten Baessrmann, Markus Lubeck, Andrew Pitt<br />
Prohibitin Isoforms In Colorectal Cancer: A Proteomic Study<br />
Paula Álvarez Chaver (Universidad De Vigo, Spain), Francisco Javier Rodríguez<br />
Berrocal, María Páez De La Cadena, Ana María Rodríguez Piñeiro, Vicenta Soledad<br />
Martínez Zorzano<br />
Proteins Potentially Involved In F508del-Cftr Trafficking Restoration Process<br />
Patricia Alves (Laboratorio de Proteomica, Dept. de Genética Humana, INSA-IP /<br />
Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, PORTUGAL),<br />
Ana Coelho, Francisco Couto, Paulo Nogueira, Deborah Penque<br />
Effect Of Lipid Peroxidation On Proteome Of The Hela Cell Line<br />
Sandro Argüelles Castilla (Dpto Bioquímica, Facultad de Farmacia-Universidad de<br />
Sevilla, SPAIN), Alberto Machado, Antonio Ayala<br />
Comparison Of Protein Profiles With Gene Expression Data To Select Biomarker<br />
Candidates For Estrogen Receptor Negative Breast Cancer<br />
Ji-Yeon Bae (Cancer Research Institute, Seoul National University College of<br />
Medicine, KOREA), Jong Won Lee, Wonshik Han, Jae Kyo Yi, Eun-Mi Jeong, Dong Hyun<br />
Kim, Cheolju Lee, Myeong-Hee Yu, Dong-Young Noh<br />
P-MON-017<br />
P-MON-018<br />
P-MON-0<strong>19</strong><br />
P-MON-020<br />
P-MON-021<br />
P-MON-022<br />
Comparison Of Cerebrospinal Fluid Proteins In Igg Fractions From Normal And<br />
Multiple Sclerosis Patients<br />
Natascha Helena Beyer (Statens Serum Institut, DENMARK / University of Victoria<br />
Genome BC Proteomics Centre, CANADA), Darryl Hardie, Leanne Britt Ohlund,<br />
Jette Lautrup Frederiksen, Christoph H. Borchers, Niels H.H. Heegaard<br />
Analysis Of Human Follicular Fluid Proteins By Isoelectric Focusing Fractionation<br />
Coupled To Mass Spectrometry<br />
Karel Bezstarosti (Erasmus MC, THE NETHERLANDS), Regine Steegers-Theunissen,<br />
Jeroen Demmers<br />
Withdrawn<br />
Proteins In Exhaled Breath Condensate: Identification And Pattern<br />
Karolien Bloemen (Flemish Institute for Technological Research (VITO), Environmental<br />
Toxicology, BELGIUM), Erwin Witters, Jef Hooyberghs, Kristine Desager, Greet Schoeters<br />
Comparative Proteomic Analysis Of Human Lung Cancer<br />
Butt Kwok Chu (Department of Applied Biology and Chemical Technology, The Hong Kong<br />
Polytechnic University, CHINA), CS Cho, SK Au, Leung Woon Fong, Zu Hai Long, Lo<br />
Chun Lap<br />
Withdrawn<br />
P-MON-010<br />
Overexpressed Proteins In Follicular Fluid From Infertile Patients Undergoing Ivf<br />
Therapy<br />
Kwang-Hyun Baek (Pochon CHA University, KOREA), Yong-Soo Kim, Myung-Sun Kim,<br />
Bum-Chae Choi, Sang-Jin Song, Dong-Hyun Cha<br />
P-MON-023<br />
P-MON-024<br />
Withdrawn<br />
Comprehensive Proteomic Analysis Of The Endometrial Fluid Aspirate<br />
Juan Casado-Vela (CICBiogune. Proteomics Unit. Technology Park of Bizkaia, SPAIN),<br />
Eva Rodriguez-Suarez, Juan Antonio García-Velasco, Roberto Matorras, Sandra<br />
González, Amagoia Ametzazurra, Daniel Nagore, Jose M. Mato, Felix Elortza<br />
68 69
P-MON-025<br />
Quantitative Analysis Of Malignant Pleural Mesothelioma Cell Surface Proteins<br />
Ferdinando Cerciello (Institute for Molecular Systems Biology, ETH Zurich,<br />
SWITZERLAND), Bernd Wollscheid, Damaris Bausch-Fluck, Colette Bigosch, Reto Ossola,<br />
Rolf Stahel, Ruedi Aebersold, Annemarie Ziegler<br />
P-MON-037<br />
Ultra-Sensitive Analysis Of Cancer Leakage Biomarkers Using The Proximity<br />
Ligation Technology<br />
Spyros Darmanis (Uppsala University, SWEDEN), Ulf Landegren, Masood Kamali-<br />
Moghaddam, Anders Alderborn<br />
P-MON-026<br />
P-MON-027<br />
P-MON-028<br />
Serum Proteome Profiling Of Cystic Fibrosis Patients: A 2de-Ms And Lc-Ms/Ms<br />
Approach<br />
Nuno Charro (Laboratorio Proteomica, Deptº. Genetica Humana INSA, PORTUGAL<br />
/ Clinical Proteomics Facility, University of Pittsburgh Medical Centre, USA), Bruno<br />
Alexandre, Paula Pacheco, António de Almeida, Thomas Conrads, Deborah Penque<br />
Identification Of Disease Regulated Serum Proteins In Lung Cancer Of C-Myc<br />
And C-Raf Transgenic Mice<br />
Bijon Chatterji (Fraunhofer ITEM, GERMANY), Juergen Borlak<br />
Hsp27 And Prx-2: Potential Clinical Biomarkers For Barrett’s Esophagus Early<br />
Detection, Therapy And Prognosis<br />
Yan Cheng (Department of Gastroenterology, CHINA), Jun Zhang<br />
P-MON-038<br />
P-MON-039<br />
P-MON-040<br />
Integration Of Proteomics And Genomics To Identify Biomarkers For Colon Cancer<br />
Meike de Wit (Department of Pathology, VU University medical center, THE<br />
NETHERLANDS), Connie R. Jimenez, Beatriz Carvalho, Sander Piersma, Rolf<br />
Lamerichs, Gerrit A. Meijer, Remond J.A. Fijneman<br />
Peptidome Profiling Of Ovarian Cancer By Maldi-Tof/Ms<br />
Anna Della Corte (‘John Paul II’ Center-Catholic University, ITALY), Marco D’Imperio,<br />
Michela Di Michele, Maria De Ninno, Maria Benedetta Donati, Domenico Rotilio<br />
Cell Surface Protein Profiling And Identification Of Galectin-1 As A Potential Renal<br />
Cell Carcinoma Biomarker Using Cell Culture On Proteinchip And Maldi-Tof Ms<br />
Hassan Dihazi (Nepehrology & Rheumatology, Medical Center Goettingen, GERMANY),<br />
Claudia Mueller, Abdul R. Asif, Thomas Flad, Abderrahim Elmaouhoub, Gerhard A. Mueller<br />
P-MON-029<br />
P-MON-030<br />
P-MON-031<br />
P-MON-032<br />
P-MON-033<br />
P-MON-034<br />
P-MON-035<br />
P-MON-036<br />
Quantitative Proteomic Analysis Of Human Amniotic Fluid<br />
Chan-Kyung J. Cho (University of Toronto, Mount Sinai Hospital, CANADA),<br />
Christopher Smith, Elizabeth Winsor, Eleftherios Diamandis<br />
Comparison Of Secreted Protein Expression From Hepg2 Cells Exposed To<br />
Benzo(A)Pyrene And Benz(A)Anthracene<br />
Seonyoung Choi (Korea University, KOREA), Zhi Zheng, Eunkyung Cho, Ji-Young Lee,<br />
Min Lee, So-Young Park, Donggeun Sul<br />
An Optimized Time Alignment Algorithm: Cow Using Coda-Selected Mass<br />
Chromatograms<br />
Christin Christin (Department of Analytical Biochemistry, University of Groningen,<br />
THE NETHERLANDS), Age Smilde, Huub Hoefsloot, Frank Suits, Rainer Bischoff,<br />
Peter Horvatovich<br />
Proteomic Profiling Of Normal Human Tears<br />
CY Chu (The Chinese University of Hong Kong, CHINA), JCF Pong, TCW Poon, CC<br />
Wang, CP Pang<br />
Identification Of Potential Biomarkers For The Detection Of Breast Cancer By<br />
Seldi-Tof Ms<br />
Liping Chung (Kolling Institute of Medical Research, University of Sydney, AUSTRALIA),<br />
Sabah Shibli, Deborah Marsh, Katrina Moore, Robert Baxter<br />
Identification And Characterization Of New Blood-Accessible Colorectal Cancer<br />
Biomarkers<br />
Paolo Conrotto (ETHZ, SWITZERLAND), Jascha Rybak, Dario Neri, Philippe Kischel,<br />
David Waltregny, Vincent Castronovo<br />
Identification Of Differentially Expressed Plasma Membrane Proteins In Renal<br />
Cancer<br />
Vassilis Aggelis, Rachel Craven (Cancer Research UK Clinical Centre, UNITED KINGDOM),<br />
Robert Tonge, Jianhe Peng, Patricia Harnden, Peter Selby, Rosamonde Banks<br />
Identification Of Differentially Expressed Proteins In Acute Coronary Syndromes<br />
Veronica M. Darde (Immunology Department. Fundacion Jimenez Diaz / Proteomics<br />
Unit. Hospital Nacional de Paraplejicos. SESCAM, SPAIN), Maria G. Barderas, Fernando de<br />
la Cuesta, Julio J. Nacher, Lorenzo Lopez-Bescos, Jose Tunon, Jesus Egido, Fernando Vivanco<br />
P-MON-041<br />
P-MON-042<br />
P-mon-043<br />
P-MON-044<br />
P-MON-045<br />
P-MON-046<br />
P-MON-047<br />
P-MON-048<br />
Mrm Assay Development For Targeted Proteomics Of Genomics Candidates For<br />
Progression Of Crc<br />
Joerg Dojahn (Applied Biosystems Germany, GERMANY), Beatriz Carvalho, Jakob<br />
Albrethsen, Jaco C. Knol, Matthias Glückmann, Christof Lenz, Connie R. Jimenez,<br />
Gerrit A. Meijer<br />
SELDI-TOF-MS Meets BN-PAGE: Combining Protein Interaction Studies And<br />
Biomarker Discovery<br />
Niko Escher (Institute of Human Genetics and Anthropology, GERMANY), Robert Kob,<br />
Melle Christian, Ferdinand von Eggeling<br />
Comparative Proteomic Analysis Of Korean Native Cattle Muscle From Different<br />
Depots<br />
Jang Eun Jeong (National Institute of Animal Science, KOREA), Park Soo-Jin, Park<br />
Mi-Rim, Kwon Seulmina, Hong Sung-Gu, Kim Dong-Woon, Lee Hyun-Jeong<br />
Global Mapping Of Transcription Factor Expression Patterns<br />
Jeffrey Falk (Aviva Systems Biology, UNITED STATES), Lingxun Duan, Mingjie Jin,<br />
Dongyan Liu, Xiang Dong Fu<br />
A Quantitative Immunoaffinity Enrichment – LC/MS/MS Method For MMP9 From<br />
Mouse Serum<br />
Mireia Fernandez Ocana (Pfizer, UNITED KINGDOM), Hendrik Neubert, Phil Clarke,<br />
Mark Fidock<br />
Identification Of Colorectal Cancer Biomarkers From Mouse Colon Tumor Secretome<br />
Remond J.A. Fijneman (VU University Medical Center, Dept. of Medical Oncology /<br />
Dept. of Pathology, THE NETHERLANDS), Meike de Wit, Maral Pourghiasian, Sander<br />
Piersma, Pien M. van Diemen, Victor W.H. van Hinsbergh, Ron Smits, Riccardo<br />
Fodde, Gerrit A. Meijer, Connie R. Jimenez<br />
Biomarker Discovery In A Mouse Model Of Trait Anxiety<br />
Michaela Filiou (Laboratory of Proteomics and Biomarkers, GERMANY), YY Zhang, B Bisle,<br />
E Frank, MS Kessler, K Haegler, G Maccarrone, B Hambsch, R Landgraf, CW Turck<br />
Differential Protein Expression Analysis Of Endothelial Cells Treated With<br />
Growth Factors<br />
John Flensburg (GE Healthcare Bio-Sciences AB, SWEDEN), Mandana Fasth, Fuad<br />
Bahram, Lena Claesson-Welsh<br />
70 71
P-MON-049<br />
P-MON-050<br />
P-MON-051<br />
P-MON-052<br />
Separation Of Endogenuous Plasma Adiponectin Oligomers And Isoforms Using<br />
Free Flow Electrophoresis<br />
Aude Foucher (BD, UNITED STATES), Craig Gelfand<br />
Diagnostic Plasma Biomarkers Of Alcoholism In Non-Human Primates<br />
Willard M Freeman (Penn State College of Medicine, UNITED STATES), Pamela Noto,<br />
Heather VanGuilder, Kathleen Grant, Kent Vrana<br />
Withdrawn<br />
Proteomics And Molecular Markers In Cin2-3 Punch Biopsies And Normal<br />
Cervical Epithelium<br />
Ane Cecilie Munk, Cristina Furlan (Department of Pathology, Stavanger University<br />
Hospital, NORWAY), Ivar Skaland, Emiel Janssen, Cato Brede, Kjell Løvslett, Bent<br />
Fiane, Stein-Tore Nilsen, Jan P.A. Baak, Anne Bjørnstad<br />
P-MON-063<br />
P-MON-064<br />
P-MON-065<br />
Role Of Pkc¦Â In Hepatocellular Carcinoma Cells Migration And Invasion: A<br />
Potential Therapeutic Target<br />
Kun Guo (Liver Cancer Institute, Zhong shan Hospital, Fudan University / Research<br />
Center for Cancer, Institute of Biomedical Science, Fudan University, CHINA),<br />
Xiaonan Kang, Yan Li, Xuefei Li, Lu Sun, Yinkun Liu<br />
Quantitative Proteomic Analysis Of The Matrix Proteins From Human Dermal<br />
Fibroblasts<br />
Moon Kyung Ha (Department of Biochemistry and Molecular Biology, SOUTH KOREA),<br />
Haeri Choi, Young Hoon Son, Jiheon Rhim, Sung Chun Cho, Sang Chul Park<br />
A New Strategy For Plasma Protein Biomarker Discovery In Ovarian Cancer<br />
Ruth Hüttenhain (Institute of Molecular Systems Biology, ETH Zurich / Competence<br />
Center of Systems Physiology and Metabolic Diseases, ETH Zurich, SWITZERLAND),<br />
Daniela Dinulescu, Bruno Domon, Ruedi Aebersold<br />
P-MON-053<br />
P-MON-054<br />
P-MON-055<br />
P-MON-056<br />
Identification Of Differentially Expressed Genes Between Diabetes VS Healthy<br />
Srinubabu Gedela, Appa Rao Allam (Andhra University College of Engineering, INDIA)<br />
Proteomic Analysis Of Differentially Expressed Proteins In Swiss Mice Following<br />
Glyphosate Exposure<br />
Jasmine George (Indian Institute of Toxicolgy Research, INDIA), Preeti Roy,<br />
Yogeshwer Shukla<br />
Stratification And Monitoring Of Juvenile Arthritis Patients By Synovial<br />
Proteome Profile<br />
David Gibson (Arthritis Research Group, Queen’s University Belfast, UNITED KINGDOM),<br />
Sarah Blelock, Sorcha Finnegan, Caitriona Scaife, Stephen Pennington, Michael Dunn<br />
The Candida Immunome As A Mine For Clinical Biomarker Development For<br />
Invasive Candidiasis<br />
Aida Pitarch, César Nombela, Concha Gil (Department of Microbiology II, Faculty of<br />
Pharmacy, Complutense University of Madrid, SPAIN)<br />
P-MON-066<br />
P-MON-067<br />
P-MON-068<br />
P-MON-069<br />
Peptidome And Proteome Analyses Of Lymph Nodes In A Mouse Model Of<br />
Chemical-Induced Asthma<br />
Steven Haenen (K.U. Leuven, BELGIUM), Elke Clynen, Jeroen Vanoirbeek, Peter Hoet,<br />
Liliane Schoofs<br />
Absolute Quantitation Of Endogenous Peptides Using High Resolution Selected<br />
Reaction Monitoring<br />
Reiko Kiyonami, Rosa Viner, Vlad Zabrouskov, Akraporn Prakobphol, H. Ewa Witkowski,<br />
Steven C. Hall, Susan J. Fisher, Markus Hardt (Thermo Fisher Scientific, UNITED STATES)<br />
Proteomics And Subproteomics In The Quest For New Diagnostic Leads In Human<br />
Disease<br />
Niels H.H. Heegaard (Statens Serum Institut, DENMARK)<br />
Promising Tool For Diagnostic Evaluation Of Hepatitis Induced Fibrogenesis<br />
Corinna Henkel (Institute of Pathology, RWTH University Hospital Aachen, GERMANY),<br />
Kristina Schwamborn, Olav Gressner, Margarete Odenthal, Ruth Knuechel, Ralf Weiskirchen<br />
P-MON-057<br />
P-MON-058<br />
P-MON-059<br />
P-MON-060<br />
P-MON-061<br />
P-MON-062<br />
Identification Of Parkinson’s Disease Markers By Systematic Screening Of<br />
Protein Arrays<br />
Heike Goehler (Medizinisches Proteom-Center, Ruhr-University Bochum, GERMANY),<br />
Axel Kowald, Angelika Lueking, Christian Scheer, Florian Tribl, Manfred Gerlach,<br />
Peter Riederer, Katrin Marcus, Helmut E. Meyer<br />
Withdrawn<br />
Proteomic Analysis Of Urine From Patients With Urologic Chronic Pelvic Pain<br />
Syndromes<br />
Young Ah Goo (University of Washington, UNITED STATES), Clair Yang, Priska von<br />
Haller, Alvin Liu, David Goodlett<br />
The Evolution Of Tissue Markers Analyzed By Maldi-Ms Imaging<br />
Richard Goodwin (Institute of Biomedical and Life Sciences, University of Glasgow,<br />
UNITED KINGDOM), Stuart Cobb, Andrew Pitt<br />
Identification Of Protein Biomarker For Schizophrenia In The Postmortem<br />
Prefrontal Cortex Using 2D Electrophoresis Analysis<br />
Maria Jose Guerrero (Proteomika S.L, SPAIN), Marcel Ferrer-Alcón, Laureano<br />
Simón, Antonio Martinez, Jose Javier Meana<br />
Investigation Of The Serum Proteome To Look For Ionizing Radiation Biomarkers<br />
Olivier Guipaud (Institut de Radioprotection et de Sûreté Nucléaire, FRANCE), Marie<br />
Thézénas, Valérie Holler, Joëlle Vinh, Marc Benderitter<br />
P-MON-070<br />
P-MON-071<br />
P-MON-072<br />
P-MON-073<br />
P-MON-074<br />
P-MON-075<br />
Validation Of High Throughput Protein Biomarker Assays<br />
Nicholas B. Herold (Quadraspec, Inc., UNITED STATES), Fred E. Regnier, Chad W. Barden<br />
Targeted Proteomics Of Transcription Factors In Breast Cancer And Embryonic<br />
Stem Cells<br />
Johannes Hewel (Terrence Donnelly Centre for Cellular and Biomolecular Research,<br />
University of Toronto, CANADA), Charanjit Sandhu, Kento Onishi, Peter Zandstra,<br />
Andrew Emili<br />
Multi-Institutional Validation Of Plasma Biomarker Of Pancreatic Cancer By<br />
MALDI-TOF-MS<br />
Kazufumi Honda (Cancer Proteomics Project National Cancer Center Research<br />
Institute, JAPAN), Masaya Ono, Tesshi Yamada<br />
Withdrawn<br />
Mining The Serum Proteome For Cervical Cancer Biomarkers<br />
Péter Horvatovich (University of Groningen, THE NETHERLANDS), Natalia<br />
Govorukhina, Iwona Sobczak-Elbourn, Krisztina Páal, Frank Suits, Peicheng Du,<br />
Christin Christin, Berend Hoekman, Ate van der Zee, Rainer Bischoff<br />
A Search For Biomarkers Of Type 1-Diabetes By Lc-Esi-Itraq And Label Free<br />
Lc-Maldi Serum Proteomics<br />
Waltteri Hosia (Turku Centre for Biotechnology, FINLAND), Robert Moulder, Heidi<br />
Vähämaa, Jussi Salmi, Tero Aittokallio, Mikko Katajamaa, Olli Simell, Olli Nevalainen,<br />
Riitta Lahesmaa, et.al.<br />
72 73
P-MON-076<br />
Identification And Evaluation Potential Biomarkers Of Human Glioblastoma Multiforme<br />
Chiungyin Huang (Chang-Gung Memorial Hospital, TAIWAN), Li-Ying Feng, Jyh-Wei Shin,<br />
Kuo-Chen Wei<br />
P-MON-089<br />
Proteomic Analyses Of Microbial Activity In The Human Gut – The Beginning<br />
Carolin Kolmeder (Department of Basic Veterinary Sciences, University of Helsinki,<br />
FINLAND), Anne Salonen, Airi Palva, Willem M. de Vos<br />
P-MON-077<br />
A Novel System For Efficiently Screening Tumor-Related Proteins Using Antibody<br />
Proteomics<br />
Sunao Imai (NiBio / Osaka University, JAPAN), Shin-ichi Tsunoda, Yasunobu Yoshida,<br />
Shinsaku Nakagawa, Junya Fukuoka, Yasuo Tsutsumi<br />
P-MON-090<br />
Apc-Binding Protein EB1 Is Novel Prognostic Biomarker In Hepatocellular Carcinoma<br />
Tatsuya Orimo, Hidenori Ojima, Nobuyoshi Hiraoka, Shigeru Saito, Satoru Todo,<br />
Setsuo Hirohashi, Tadashi Kondo (Proteome Bioinformatics Project, National Cancer<br />
Center Research Institute, JAPAN)<br />
P-MON-078<br />
P-MON-079<br />
P-MON-080<br />
P-MON-081<br />
P-MON-082<br />
P-mon-083<br />
Characterization Of Inflammatory/Oxidative Stress Protein Modifications<br />
Jon Jacobs (Pacific Northwest National Laboratory, UNITED STATES), Weijun Qian,<br />
Diana Bigelow, Collette Sacksteder, Richard Corley, Joel Pounds<br />
Proteome Analysis For Identification And Validation Of Potential Biomarkers In<br />
Colorectal Cancer<br />
Lucy Jankova (ANZAC Research Institute, AUSTRALIA)<br />
Protein Profiles Differentiating Triple Negative Breast Cancer From Er/Pgr<br />
Expressing Breast Cancer<br />
Eun-Mi Jeong (Cancer Research Institute, Seoul National University College of Medicine,<br />
KOREA), Jong Won Lee, Wonshik Han, Ji-Yeon Bae, Jae Kyo Yi, Dong Hyun Kim,<br />
Cheolju Lee, Myeong-Hee Yu, Dong-Young Noh<br />
Parallel Analysis Of Proteomic And Metabolic Profiles On Nonalcoholic Fatty<br />
Liver Disease<br />
Ying Jiang (State Key Laboratory of Proteomics, Beijing Proteome Research Center,<br />
Beijing Institute of Radiation Medicine, CHINA), Hao Li, Lan Wang, Youming Li, Fuchu He<br />
Antibody Pattern And Retinal Ganglion Cell Loss In A Heat Shock Protein<br />
Immunization Animal Model<br />
Stephanie Joachim (Experimental Ophthalmology, GERMANY), Martin Wax, Norbert<br />
Pfeiffer, Franz Grus<br />
Proteomic Anaysis Of Differentially Expressed Proteins In Colorectal Cancer<br />
Kee Kang (Deaprtment of Biochemistry, Gyeongsang National University School of<br />
Medicine, KOREA), Jung-Hun Kang, Young-Tae Joo, Eun-Jung Jung, Gyeong-Won Lee,<br />
Hoon-Gu Kim, Hee Cho, Bok Cho, Sang-Kyung Choi<br />
P-MON-091<br />
P-MON-092<br />
P-MON-093<br />
P-MON-094<br />
P-MON-095<br />
IsoAsp7-containing Beta-Amyloid As A Potential Biomarker Of Alzheimer’s Disease<br />
Philipp Tsvetkov, Igor Popov, Eugene Nikolaev, Alexander Archakov, Alexander Makarov,<br />
Sergey Kozin (Orekhovich Institute of Biomedical Chemistry, Russian Academy of<br />
Medical Science, RUSSIAN FEDERATION)<br />
Guided Interpretation Of Clinical Proteome Profiling In Acute Myocardial Infarction<br />
Markus Kubicek (Department of Medical and Chemical Laboratory Diagnostics,<br />
Medical University of Vienna, AUSTRIA), Klaus Distelmaier, Rene Stempfer, Daniela<br />
Dunkler, Susanne Winkler, Johannes Jakowitsch, Helge Wimmer, Christopher Gerner,<br />
Irene Lang, Oswald Wagner<br />
Ovarian Cancer Ascites Fluid Subproteome: Home Of Potential Biomarkers For<br />
Ovarian Cancer<br />
Cynthia Kuk (Department of Laboratory Medicine and Pathobiology, University of<br />
Toronto / Department of Pathology and Laboratory Medicine, Mount Sinai Hospital,<br />
CANADA), Antoninus Soosaipillai, Vathany Kulasingam, Chris R. Smith, Ihor Batruch,<br />
Eleftherios P. Diamandis<br />
Spermatozoa Fertility Biomarkers Display by Intact Cells MALDI-TOF Mass Spectrometry<br />
Valérie Labas (INRA, Plate-forme de Protéomique Analytique et Fonctionnelle –<br />
Laboratoire de Spectrométrie de Masse, FRANCE), Clémence Belleannee, Maya<br />
Belghazi, Françoise Dacheux, Jean-Louis Dacheux<br />
Biomarker Discovery By MRM – Combining Sensitivity With Throughput<br />
Vinzenz Lange (Competence Center for Systems Physiology and Metabolic Diseases<br />
/ Institute for Molecular Systems Biology, ETH Zürich, SWITZERLAND), Carsten<br />
Danzer, Alexander Schmidt, Katrin Eckhardt, Reto Ossola, Bruno Domon, Wilhelm<br />
Krek, Ruedi Aebersold<br />
P-MON-084<br />
P-MON-085<br />
P-MON-086<br />
P-MON-087<br />
Reduced Level Of Peroxiredoxin Proteins In Cancer Determined Using Stable<br />
Isotope Labeled Quantitative Plasma Analysis<br />
Hiroyuki Katayama (Fred Hutchinson Cancer Research Center, JAPAN), Vitor Faca,<br />
Sandra Faca, Sharon Pitteri, Ji Qiu, Hong Wang, Alexei Krasnoselesky, Lisa Newcomb,<br />
Qing Zhang, Sam Hanash<br />
Disease-Specific Serum Peptides In Patients With Systemic Sclerosis<br />
Ynag Xiang, Toshihiro Matsui, Mitsumi Arito, Naoya Suematsu, Kazuo Yudoh,<br />
Tomohiro Kato (Clinical Proteomics and Molecular Medicine, St. Marianna University<br />
Graduate School of Medicine, JAPAN)<br />
The ‘Blood Donor Biobank’: An Innovative Resource For Biomarker Research<br />
Claudia Kellner (Blutspendedienst des Bayerischen Roten Kreuzes gGmbH, GERMANY)<br />
Proteomic Analysis Identifies S100A8 And S100A9 As Serological Markers For<br />
Colorectal Cancer<br />
Hye-Jung Kim (Life Sciences Division, Korea Institute of Science and Technology /<br />
Department of Biochemistry, College of Science, Yonsei University, KOREA), Hyun Ju<br />
Kang, Seung-Taek Lee, Myeong-Hee Yu, Hoguen Kim, Cheolju Lee<br />
P-MON-096<br />
P-MON-097<br />
P-MON-098<br />
P-MON-099<br />
Analysis Of Serum Glycoproteins Relevant To Breast Cancer By An Indirect<br />
Approach Using Hs578T Cells<br />
Younghee Ahn, Un-Beom Kang, Myeong-Hee Yu, Cheolju Lee (Life Sciences Division,<br />
Korea Institute of Science and Technology, KOREA)<br />
Selection And Validation Of Liver Cancer Biomarker Candidates From Human<br />
Plasma Proteome<br />
Ju Yeon Lee (Korean Basic Science Institute, KOREA)<br />
Identification Of Inadequately Expressed Proteins In Plasma Of Recurrent<br />
Spontaneous Abortion (RSA) Patients<br />
Min-Young Lee (Graduate School of Life Science and Biotechnology, Pochon CHA<br />
University, CHA General Hospital, KOREA), Myung-Sun Kim, Bon-Hee Gu, Jong-Ho<br />
Choi, Sangjin Song, Bum-Chae Choi, Kwang-Hyun Baek<br />
Proteomic Analysis In The Substantia Nigra Of The Mouse Exposed To The Paraquat<br />
Sujin Lee (School of Life Sciences & Biotechnology, College Of Natural Sciences,<br />
Kyungpook National University, KOREA), Sun-Mi Yun, Hyun Tae Kim, Ung-Kyu Choi,<br />
Nam Sik Eum, Gui-hyang Choi, Song Cui, Tae-Cheon Kang, Soo Young Choi, Oh-Shin Kwon<br />
P-MON-088<br />
Identification Of PGK1 As Biomarker For Oxidative Stress<br />
Jong Sang Kim (Kyungpook National University, School of Life and Food Sciences,<br />
KOREA), Chan Ho Jang, In Ae Lee, Lesley Quintos, Mi Kyung Sung, Sung Joon Lee<br />
P-MON-100<br />
Proteome Profiling Of Primary Mammary Epithelial Cells Derived From MMTVneu<br />
Mice<br />
Taehoon Lee (Sigmol Inc., THE NETHERLANDS), Incheol Shin, Sungwoo Park, Dong Young Noh<br />
74 75
P-MON-101<br />
Proteomic Profiling For Candidate Biomarkers Of Breast Cancer Response To<br />
Chemotherapy<br />
Sharon Leong (Kolling Institute of Medical Research, The University of Sydney,<br />
AUSTRALIA), Samath Pen, Richard Christopherson, Robert Baxter<br />
P-MON-114<br />
Proteomics Analysis Of Isolated Membrane Fractions From Normal And<br />
Cancerous Breast Cell Lines<br />
Priyanka Maurya (National Institute for Cellular Biotechnology, IRELAND), Michael<br />
Henry, Martin Clynes, Paula Mealedy<br />
P-MON-102<br />
P-MON-103<br />
P-MON-104<br />
P-MON-105<br />
P-MON-106<br />
P-MON-107<br />
P-MON-108<br />
P-MON-109<br />
Withdrawn<br />
Quantitative, Top-Down Identification Of Differentially Expressed, Endogenous<br />
Peptides In Maternal Serum<br />
Mary F Lopez, David Sarracino (ThermoFisher Scientific BRIMS, UNITED STATES),<br />
Bryan Krastins, Kypros Nicolaides, Michael Athanas, Amol Prakash<br />
Discovery Of Mechanistic Biomarkers With A Causal Network Model Of Gefitinib<br />
In Cancer<br />
Joseph Loureiro (Genstruct, Inc., UNITED STATES), Gil Blander, Ben Wong, Ailan Guo,<br />
Dave Merberg, Christian Reich, Michael Comb, Keith Elliston<br />
Proteomic Analysis Of Circulating Immune Complexes Reveals Disease-Associated<br />
Proteins<br />
Jason Low (Saint Louis University School of Medicine, UNITED STATES), Anil Chauhan,<br />
David Gibson, Mengmeng Zhu, Sixue Chen, Madeleine Rooney, Terry Moore<br />
Identification Of Significantly Differentially Expressed Peptides In Pre-Eclamptic<br />
Tissue<br />
Theo M. Luider (Dept. of Neurology, Erasmus Medical Center, THE NETHERLANDS),<br />
Coskun Guzel, Christianne JM de Groot, Eric A.P. Steegers<br />
Diagnostic Information Of Serum Protein Profiling Independent Of CA125 In<br />
Ovarian Tumors<br />
Anne Kjaergaard Callesen, Jonna Skov Madsen (Department of Clinical Biochemistry,<br />
Vejle County Hospital, DENMARK)<br />
Proteomic Screen Identifies A Panel Of Proteins Indicative Of Response To Gefitinib<br />
Parag Mallick (Cedars-Sinai Medical Center / UCLA, UNITED STATES)<br />
Proteomic Profiling Of Retinoblastoma: A Preliminary Study<br />
K Mallikarjuna (Vision Research Foundation, Sankara Nethralaya, INDIA), S Krishnakumar,<br />
J Biswas, PR Deepa, V Khetan, T Sharma, L Gopal, CS Sundaram, Y Sharma<br />
P-MON-115<br />
P-MON-116<br />
P-MON-117<br />
P-MON-118<br />
P-MON-1<strong>19</strong><br />
P-MON-120<br />
The Development Of An Mrm Assay For Quantitation Of Low Abundance<br />
Cytochrome P450 Proteins<br />
Therese McKenna (Waters Corporation MS Technologies Centre, UNITED KINGDOM),<br />
Amy Bartlett, Christopher Hughes, Johannes Vissers, Scott Geromanos, Catalin<br />
Donneanu, James Langridge<br />
Bronchoalveolar Lavage Fluid Proteomics Patterns In Sulfur Mustard Exposed<br />
Patients<br />
Hossein Mehrani (Baqiyatallah University of Medical Sciences, IRAN), Mostafa Ghanei,<br />
Jafar Aslani, Leila Golmanesh<br />
A Label Free Quantitative Proteomic Strategy And Its Application In Biomarker<br />
Discovery Based On LC-ESI-MS/MS<br />
Chen Ming (Tianjing Institute of Hygiene and Environmental Medicine /Beijing Proteome<br />
Research Center, CHINA), Ying Wantao, Qian Lingjia, Qian Xiaohong<br />
Bioinformatics For Proteomic Analyses Applied To Metastatic Disease In<br />
Prostate Cancer<br />
Alberto Molares Vila (Department of Analytical Chemistry, Chemistry Faculty, University<br />
of Vigo / Biomedical Foundation of Vigo University Hospital, SPAIN), Alejandro Gómez<br />
Pinillos, Gonzalo Gómez López, María del Val Toledo Lobo, Juan Oses Prieto, Antonio<br />
Ojea Calvo, Enrique Caso Peláez, Ana Gago Martínez<br />
Determination Of Biomarkers Of Skin Disease By MALDI-MS And MALDI-MSI In<br />
Vitro Skin Models<br />
Tasneem Muharib (Biomedical Research Centre, UNITED KINGDOM), Vikki Carolan,<br />
Duncan Rimmer, John White, Malcolm Clench<br />
Using Different Proteomics Techniques To Identify Glioma- Neovascularisation-<br />
Related Proteins<br />
Dana Mustafa (Erasmus MC, Pathology department, THE NETHERLANDS), Peter<br />
Burgers, Lennard Dekker, Rober-Jan Lamers, Halima Charif, Mark Titular, Peter<br />
Sillevis Smith, Theo Luider, Johan Kros<br />
P-MON-110<br />
P-MON-111<br />
Cleft Palate Regulated Salivary Proteins<br />
Reka Tihanyi (Institute of Biochemistry and Medical Chemistry, Medical School,<br />
University of Pecs, HUNGARY), Tamas Gyula Szabo, Gyula Szabo, Viktoria Nemeth,<br />
Alexandra Vaczy, Balazs Sumegi, Laszlo Mark<br />
Development Of Instrument Parameters For Maximum Product Ion Formation In<br />
MRM MS<br />
Daniel Martin (Institute for Systems Biology, UNITED STATES), Ashley Eastham,<br />
Amelia Peterson, Li Huang<br />
P-MON-121<br />
P-MON-122<br />
Identification And Characterization Of YPRC-G1, An N-Linked Glycoprotein And<br />
Putative Biomarker For Hepatocellular Carcinoma<br />
Keun Na (Yonsei Proteome Research Center, Department of Biochemistry, Yonsei<br />
University, KOREA), Eun-Young Lee, Hyoung-Joo Lee, An-Sung Jeong, Kwang-Youl Kim,<br />
Min-Seok Kwon, Hanna Lee, Sang-Yon Cho, Hoguen Kim, Young-Ki Paik<br />
Comparison Of Different Immunoaffinity Columns To Remove High Abundant<br />
Proteins From Follicular Fluid Of Different Species<br />
Somayyeh Nadaf (INRA, FRANCE)<br />
P-MON-112<br />
P-MON-113<br />
Proteome Analysis Of Schizophrenia Brain Tissue<br />
Daniel Martins de Souza (Max-Planck-Institut für Psychiatrie and Laboratório de<br />
Neurociências, GERMANY / Instituto de Psiquiatria – Faculdade de Medicina da USP,<br />
BRAZIL) Giuseppina Maccarrone, Wagner F. Gattaz, Andrea Schmitt, Emmanuel<br />
Dias-Neto, Chris W. Turck<br />
Prostate Cancer Biomarkers To Predict Response To Immunotherapy<br />
Balwir Matharoo-Ball (The John Van Geest Cancer Research Centre, UNITED KINGDOM),<br />
Christophe Lemetre, Vicky Adams, Else-Marit Inderberg Suso, Stephen Ward,<br />
Gustav Gaudernack, Graham Ball, Robert Rees<br />
P-MON-123<br />
P-MON-124<br />
Methods For High-Throughput Analysis Of The Urinary Proteome<br />
Nagarjuna Nagaraj (MPI Biochemie, GERMANY), Alexandre Zougman, Juergen Cox,<br />
Matthias Mann<br />
MS Approaches To Address The Role Of An Amyloid-B In Alzheimer’s Plague<br />
Formation Onset<br />
Evgeny Nikolaev (The Institute for Energy Problems of Chemical Physics / Orekhovich<br />
Institute of Biomedical Chemistry / Emanuel Institute of Biochemical Physics, Russian<br />
Academy of Science, RUSSIA), Igor Popov, Sergey Kozin, Elena Kugaevskaya,<br />
Alexander Archakov, Alexey Kononikhin<br />
76 77
P-MON-125<br />
P-MON-126<br />
Pharmaco-Proteomics At The Clinical Blood – Brain Junction<br />
MingMing Ning (Clinical Proteomics Research Center, Dept of Neurology, Mass<br />
General Hospital/Harvard Medical School, UNITED STATES), Ferdinando Buonanno,<br />
Dave Sarracino, Mary Lopez, Dayse Sena, Diana Walleigh, Xiaoying Wang, David McMullin,<br />
Eng H. Lo<br />
Identifying Candidate Biomarkers Of Exposure To The Mycotoxin Deoxynivalenol<br />
Using Proteomics<br />
Andre Nogueira da Costa (Molecular Epidemiology Unit, Centre for Epidemiology and<br />
Biostatistics, LIGHT Laboratories, UNITED KINGDOM), Renée S. Mijal, Jeff Keen,<br />
John Findlay, Christopher P. Wild<br />
Innovation In Peptide & Protein Seperation Technologies<br />
P-MON-127<br />
P-MON-128<br />
P-MON-129<br />
P-MON-130<br />
Isolation Of Protein Isoforms By Free Flow Electrophoresis Preserving Biological<br />
Activity<br />
Afsaneh Abdolzade-Bavil (Becton Dickinson GmbH, Planegg, GERMANY), Christian<br />
Obermaier, Siegfried Hirler, Mikkel Nissum, Christoph Dufter, Gerhard Weber,<br />
Christoph Eckerskorn<br />
A Simple Way To Use A 1D Split-Free Nano-HPLC In An Automated 2D LC-MS/MS<br />
SETUP<br />
Michael Andersen (Proxeon Biosystems A/S, DENMARK), Paul Taylor, Mike Moran,<br />
Alexandre Podtelejnikov, Ole Vorm, Thomas Kislinger<br />
New Stain Free Gel System - Compatibility With Western Blotting And Ms Based<br />
Protein Identification<br />
Kumar Bala (Bio-Rad Laboratories, UNITED STATES)<br />
Proteomics Based On Peptide Fractionation By SDS-Free Page<br />
Vladimir Besada (Center for Genetic Engineering and Biotechnology, CUBA), Yassel<br />
Ramos, Elain Gutierrez, Yoan Machado, Aniel Sánchez, Lila Castellanos-Serra,<br />
Luis Javier González, Jorge Fernández-de-Cossio, Yasset Pérez-Riverol, Lázaro<br />
Betancourt, Jeovanis Gil, Gabriel Padrón<br />
P-MON-137<br />
P-MON-138<br />
P-MON-139<br />
P-MON-140<br />
P-MON-141<br />
P-MON-142<br />
P-MON-143<br />
P-MON-144<br />
A Multi-Approach Experiment To Analyse Aphid Salivary Proteome<br />
Frederic Francis (Gembloux Agricultural University, Functional & Evolutionary<br />
Entomology, BELGIUM), Nicolas Harmel, Eric Haubruge, Edwin de Pauw<br />
Ultrasonic Assisted Protein Enzymatic Digestion Applied To Gel-Separated<br />
Proteins<br />
Marco Galesio (Requinte, Universidade Nova de Lisboa, PORTUGAL), Diana Vieira,<br />
Raquel Rial, Jose Capelo<br />
Analysis Of Active Proteins Extracted From Deer Antler By 2D-SEC-IEC<br />
Liang Gao (Dalian Institute of Chemical Physics, Chinese Academy of Sciences,<br />
CHINA), Zhen Liang, Lihua Zhang, Yushu Huo, Yukui Zhang<br />
Detection-Identification Of Trace Protein Impurities Using Combinatorial Peptide<br />
Libraries<br />
Luc Guerrier (Bio-Rad Laboratories C/o CEA-Saclay, FRANCE), Egisto Boschetti,<br />
Frederic Fortis, Pier-Giorgio Righetti<br />
Phosphopeptides: Coupling Of Immunoaffinity And TIO2 Metal Affinity<br />
Francois Guillonneau (Plateforme Proteomique Université Paris Descartes,<br />
FRANCE), Lamya Haddaoui, Patrick Mayeux, Claude Netter, Luc Camoin<br />
Separation Of Membrane Proteins And Protein Complexes Using Free-Flow<br />
Electrophoresis<br />
Kristina Hartmann (BD Diagnostics, Innovation Center Biotechnology, GERMANY),<br />
Sabine Kronbauer, Markus Islinger, Christoph Eckerskorn, Mikkel Nissum<br />
Utilization Of Immunoaffinity Interaction For Specific Antibody And Peptide Separation<br />
MD Hasan (Dalhousie University, Department of Process Engineering and Applied<br />
Science, CANADA), Yoichi Kumada, Shigeo Katoh<br />
Solid Phase Extraction - Liquid Chromatography (SPE-lc) Interface For<br />
Automated Peptide Separation And Identification By Tandem Mass Spectrometry<br />
Ole Bjeld Hørning (Proxeon A/S, DENMARK), Michael Barrett Andersen, Ole Vorm,<br />
Ole Nørregaard Jensen<br />
P-MON-131<br />
P-MON-132<br />
P-MON-133<br />
External Gradient Chromatofocusing For Quantitative Analysis Of Mammalian Lysates<br />
Karl Burgess (University of Glasgow, UNITED KINGDOM), Kit-Yee Tan, Lachislav<br />
Tsonev, Terry Sheehan, Ken Cook, Andrew Pitt<br />
Devil In IEF: Using Electric Conductivity To Monitor Salt Concentration Of 2-DE Samples<br />
Tzi-Ning Chen, Szu-Yu Wu, Ching-Yu Lin, Han-Min Chen (Department of Life-Science /<br />
Institutes of Applied Science and Engineering, Catholic Fu-Jen University, TAIWAN)<br />
Isoelectric Western Blotting (iWB) After Digital Proteome Chip (dPC) Focusing<br />
Thomas Miller, James Dasch (Protein Forest, UNITED STATES), Malcolm Pluskal,<br />
Russell Garlick, Stephen Haralampu, Bill Skea, Bhanu Singh, Dave Malarkey, Sun Tam<br />
P-MON-145<br />
P-MON-146<br />
2D Protein And Peptide Separation Of Serum By Preparative Monolithic<br />
Chromatography<br />
Linda IJsselstijn (Erasmus Medical Center, Department of Neurology, THE NETHERLANDS),<br />
Deborah Kronenberg, Remco Swart, Peter Koudstaal, Peter Sillevis Smitt, Monique<br />
Breteler, Theo Luider<br />
MSRAT, A Proteomic Sample Software Analysis Tool<br />
Oren Kagan, James Dasch, Russell Garlick, Bill Skea, Andrew Johnson (Protein Forest,<br />
Inc., UNITED STATES), Yakov Chudnovsky, David Sabatini, Eric Spooner, William Hahn,<br />
Milan Chheda<br />
P-MON-134<br />
P-MON-135<br />
P-MON-136<br />
Fast Targeted Proteomics On A Chip<br />
Zuzana Demianova (Protein Chemistry Unit, Institute of Biomedicine, University of<br />
Helsinki, FINLAND), Sami Franssila, Marc Baumann<br />
An Evaluation Of The Suitability Of 1.9 Um Particle Packed Columns For<br />
Proteomics Applications<br />
Monica Dolci, Charlotte Blythe, Dafydd Milton (Thermo Fisher Scientific, UNITED KINGDOM)<br />
Seppro® Fractionation Platform For Enhanced Detection Of Biomarkers In Biofluids<br />
Xiangming Fang (GenWay Biotech, Inc., UNITED STATES), Lei Huang, Weijun Qian,<br />
Sergey Sikora, Kimimichi Obata, Richard Smith, Wei-Wei Zhang<br />
P-MON-147<br />
P-MON-148<br />
P-MON-149<br />
Proteome Wide Analysis Of Protein Syntesis And -Breakdown In E.Coli<br />
Gertjan Kramer (University of Amsterdam, THE NETHERLANDS), Merel Nessen,<br />
Richard Sprenger, JaapWillem Back, Leo de Koning, Jan van Maarseveen, Joost<br />
Teixeira de Mattos, Klaas Hellingwerf, Luitzen de Jong, Chris de Koster<br />
SDR HyperD Resin For Detergent Removal Prior To Mass Spectrometry Analysis<br />
Hongshan Li (Pall Corporation, UNITED STATES), Saurabh Nagpal, Gurpreet Nagpal,<br />
Brian Miller, Lisa Bradbury<br />
Microchip-Based Monolithic Immobilized PH Gradient Isoelectric Focusing For<br />
Protein Analysis<br />
Yu Liang (Dalian Institute of Chemical Physics, CHINA), Yongzheng Cong, Zhen Liang,<br />
Lihua Zhang, Yukui Zhang<br />
78 79
P-MON-150<br />
P-MON-151<br />
P-MON-152<br />
P-MON-153<br />
Depletion Of High Abundance Proteins In Serum By Protein Imprinted Polymers<br />
Jinxiang Liu (National Chromatographic R. &. A. Center, Dalian Institute of Chemical<br />
Physics, CHINA)<br />
Vascular Wall Profiling Adressess Deep Proteome From Minute Samples.<br />
Sebastian Mas (Universidad Autonoma Madrid, SPAIN), Roxana Martínez-Pinna,<br />
Fernando Vivanco, Jesús Egido<br />
Simple Proteomic Complexity Reduction Strategy For Human Plasma Combines<br />
Albumin & LgG Removal With Rapid Anion Exchange Fractionation<br />
Selladurai Masilamani (Pall India Pvt Ltd, INDIA)<br />
Protein Quantification And Separation Before 2D Electrophoresis Using LFII<br />
Judit Nagy (Imperial College, UNITED KINGDOM), Fiona Pereira, Stuart Hassard, Tony Cass<br />
P-MON-163<br />
P-MON-164<br />
P-MON-165<br />
Proteomics On A Chip For Monitoring Autoimmune Diseases<br />
Richard Schasfoort (University of Twente, THE NETHERLANDS), Bianca Beusink,<br />
Dietrich Kohlheyer, Angelique Lokate, Ger Pruijn, Ad de Jong, Linda Silvertand,<br />
Natasja Carol-Visser, Albert Heck, Albert van den Berg<br />
Use Of A Novel Hydrophilic-PVDF Membrane For The Immunodetection Of<br />
Phosphorylated Proteins Separated By Gel Electrophoresis<br />
Jun Park (Millipore, UNITED STATES), Masaharu Mabuchi, Ajay Sharma<br />
Observing Rapid H/D Exchange Of The Reactive Hydrogen On The Protein<br />
Molecules By Electrospray-Assisted Laser Desorption Ionization (ELDI) Mass<br />
Spectrometry<br />
Jentaie Shiea, Jingyueh Jeng (Department of Biotechnology, Chia Nan University of<br />
Pharmacy and Science, TAIWAN), Li-Hua Lo, Yi-Tzu Cho, Cheng-Hui Yuan<br />
P-MON-154<br />
Profiling Of Low Molecular Weight Human Plasma Proteins<br />
Myung Hee Nam (Korea Basic Science Institute, KOREA), DongGuen Sul, Jong Bok Seo,<br />
Jin Hee Lee, Sohee Phark, Kun Cho<br />
P-MON-166<br />
Top-Down Proteomics Analysis Using Automated 2D LC And Fractionation<br />
Evert-Jan Sneekes (Dionex Corporation Amsterdam, THE NETHERLANDS), Bas<br />
Dolman, Remco Swart<br />
P-MON-155<br />
P-MON-156<br />
P-MON-157<br />
P-MON-158<br />
Selective Purification Of Azide-Containing Peptides From Complex Mixtures<br />
Merel A. Nessen (Mass Spectrometry of Biomacromolecules - Swammerdam<br />
Institute of Life Sciences (SILS)/ Biomolecular Synthesis - Van ´t Hoff Institute<br />
for Molecular Sciences (HIMS), University of Amsterdam, THE NETHERLANDS),<br />
JaapWillem Back, Jan H. van Maarseveen, Gertjan Kramer, Leo J. de Koning, Luitzen<br />
de Jong, Henk Hiemstra, Chris G. de Koster<br />
Processing Samples for High-Throughput Clinical Mass Spec Using Parallel<br />
Electrophoresis<br />
Jeremy L. Norris (Protein Discovery, Inc., UNITED STATES), James A. Mobley, Greg<br />
Bowersock, James B. Harkins, Benjamin B. Katz<br />
Reduction Of High Abundance Proteins In Serum, Plasma And Non-Blood Samples<br />
With Proteominer Beads<br />
Aran Paulus (Bio-Rad Laboratories, UNITED STATES), Tim Wehr, Ning Liu, Katrina<br />
Academia, Steve Freeby, Egisto Boschetti<br />
The Secretome Of H460 Non Small Cell Lung Cancer Cells: Comparing Workflows<br />
Sander Piersma (oncoproteomics laboratory / VU medical center medical oncology,<br />
THE NETHERLANDS), Simone Span, Frank Kruyt, Remond Fijneman, Connie Jimenez<br />
P-MON-167<br />
P-MON-168<br />
P-MON-169<br />
P-MON-170<br />
Optimization Of Separation Power In One-Dimensional LC In Analysis Of<br />
Proteomics Samples<br />
Bas Dolman (Dionex Corporation Amsterdam, THE NETHERLANDS), Evert-Jan Sneekes,<br />
Sebastiaan Eeltink, Remco Swart<br />
Study Of Beta-Catenin-Associated Complex By Nanoprobe-Based Affinity Mass<br />
Spectrometry<br />
An-Kai Su (Institute of Chemistry, Academia Sinica, TAIWAN), Hsin-Huang Huang,<br />
Po-Chiao Lin, Chun-Cheng Lin, Jeou-Yuan Chen, Yu-Ju Chen<br />
A Facile Buffer Exchange Interface For On-Line Hyphenation With Trypsin<br />
Microreactor<br />
Liangliang Sun (National Chromatographic Research and Analysis Center, Dalian<br />
Institute of Chemical Physics / Graduate School of Chinese Academy of Sciences, CHINA),<br />
Xiaoqiang Qiao, Dingyin Tao, Zhen Liang, Weibing Zhang, Lihua Zhang, Yukui Zhang<br />
Protein Fractioned By Microscale Solution Isoelectric Focusing And<br />
Identification By HPLC-MS/MS<br />
Dingyin Tao (Chinese Academy of Science, CHINA), Jicheng Duan, Zhen Liang, Weibing<br />
Zhang, Lihua Zhang, Yukui Zhang<br />
P-MON-159<br />
Alternative Two Dimensional Electrophoresis – Offgel Electrophoresis Combined<br />
With High Sensitivity Microfluidic On-Chip Protein Detection<br />
Tobias Preckel (Agilent Technologies R&D and Mktg. GmbH & Co.KG, GERMANY),<br />
Andreas Ruefer, Christian Wenz, Martin Greiner<br />
P-MON-171<br />
An Alternative 2D-LC-Separation Scheme For Shotgun Proteomics Coupled To<br />
ESI Or MALDI MS/MS<br />
Andreas Tholey (Saarland University, Technische Biochemie, GERMANY), Maria Lasaosa,<br />
Nathanael Delmotte, Katja Melchior, Thomas Jakoby, Elmar Heinzle, Christian Huber<br />
P-MON-160<br />
P-MON-161<br />
P-MON-162<br />
Fast And Versatile : Fluroescent Staining Of Protein In Gels With<br />
Oxacarbocyanines<br />
Mireille Chevallet (CEA / iRTSV/ LBBSI, FRANCE), Hélène Diemer, Alain van<br />
Dorsselaer, Thierry Rabilloud<br />
Highly Efficient Depletion Strategy Improves Erythrocyte Proteome Coverage<br />
Dramatically<br />
Jeffrey Ringrose (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />
University, THE NETHERLANDS), Wouter van Solinge, Shabaz Mohammed, Martina<br />
O’Flaherty, Albert Heck, Monique Slijper<br />
Guided Gas-Phase Fractionation: A Strategy To Tackle Duty-Cycle Limitations<br />
Anne Rokka (Turku Centre for Biotechnology, University of Turku & Ãbo Akademi<br />
University, FINLAND), Aschwin van der Woude, Santosh Gupta, Matthias Nees,<br />
Garry Corthals<br />
P-MON-172<br />
P-MON-173<br />
P-MON-174<br />
New MS-Based Serum Pattern Diagnostics Method Using ZipTip Technology And<br />
Ultrafiltration<br />
Ali Tiss (BioCentre and Chemistry Department, University of Reading, UNITED KINGDOM),<br />
Celia Smith, John Timms, Zhiyuan Luo, Alex Gammerman, Usha Menon, Mike Waterfileld,<br />
Ian Jacobs, Rainer Cramer<br />
New Methodology Combining Hydrophobic Gel And FT-ICR MS/MS For Membrane<br />
Protein Analysis<br />
Caroline Tokarski (Umr Cnrs 8009, FRANCE), Marianne Fillet, Christian Rolando<br />
Selective Detection And Enrichement Of Serum Albumin In Human Erythrocyte<br />
And Urine By Capillary Electrophoresis<br />
Wei-Lung Tseng (Department of Chemistry, National Sun Yat-sen University-Kaohsiung<br />
Medical University Joint Research Center, TAIWAN)<br />
80 81
P-MON-175<br />
P-MON-176<br />
P-MON-177<br />
P-MON-178<br />
P-MON-179<br />
Dyes<br />
P-MON-180<br />
P-MON-181<br />
P-MON-182<br />
P-MON-183<br />
P-MON-184<br />
P-MON-185<br />
P-MON-186<br />
Ultrasonic Assisted Protein Enzymatic Digestion For Selenium Amino-Acids<br />
Gonçalo Vale (FCT-UNL, PORTUGAL)<br />
Potential Of Long Capillary Monolithic Columns For The Analysis Of Protein<br />
Digests<br />
Michiel H.M. van de Meent (Utrecht University, THE NETHERLANDS), Gerardus J.<br />
de Jong<br />
Reproducibility Of 2D Gel-Based Proteomics Experiments<br />
David Bramwell, Mary C. Hurley, Alamgir Khan, Katrin Marcus, Jules A. Westbrook,<br />
Hans Voshol (Novartis Institutes for BioMedical Research, SWITZERLAND)<br />
An Integrated M-IPG-CIEF-Microenzymatic Reactor-Cze Platform For Protein<br />
Analysis<br />
Tingting Wang (Dalian Institute of Chemical Physics, Chinese Academy of Sciences,<br />
CHINA), Zhen Liang, Lihua Zhang, Yukui Zhang<br />
Quantitative Proteomics for 2D Gel Electrophoresis using Multiple Saturation<br />
John Wiktorowicz (The University of Texas Medical Branch, UNITED STATES), Susan<br />
Stafford, Alexander Kurosky<br />
High Sensitivity Porous Sprayer (HSPS) In Capillary Electrophoresis-Mass<br />
Spectrometry (CE-MS) For The Analysis Of Phosphopeptides<br />
Catherine C.L. Wong (The Scripps Research Institute, UNITED STATES), Chitra<br />
Ratnayake, Jeff Chapman, John R. Yates III<br />
Single Drop Microextraction Using Ag Nanoparticles For Peptide Analysis In AP-<br />
MALDI-MS<br />
Hui-Fen Wu (National Sun Yat Sen University, TAIWAN)<br />
Miniaturized Two Dimensional Capillary Electrophoresis On Microchip For Protein<br />
Analysis<br />
Cong Yongzheng (National Chromatographic R. & A. Center, Dalian Institute of<br />
Chemical Physics, Chinese Academy of Sciences, CHINA), Zhang Lihua, Liang Yu,<br />
Zhang Weibing, Zhang Yukui<br />
Column Switch Recycling Size Exclusion Chromatography For High Efficient<br />
Protein Separation<br />
Huiming Yuan (National Chromatographic Reasearch and Analysis Center, Dalian<br />
Institute of Chemical, CHINA), Lihua Zhang, Zhen Liang, Yukui Zhang<br />
Withdrawn<br />
Development Of Multi-Dimensional Chromatography-Mass Spectrometry<br />
Techniques For Protein Complex Analysis<br />
Xiangmin Zhang (Department of Chemistry / Institutes of Biomedical Sciences,<br />
Fudan University, CHINA), Jia Tang, Mingxia Gao, Chunhui Deng<br />
A New Protein Equalizer Based on M13 scFv Displaying Library<br />
Peng Zhao (Dalian Institute of Chemical Physics, Chinese Academy of Sciences,<br />
CHINA), Lihua Zhang, Zhen Liang, Yukui Zhang<br />
Molecular Mass Imaging<br />
P-MON-187<br />
P-MON-188<br />
P-MON-189<br />
P-MON-<strong>19</strong>0<br />
P-MON-<strong>19</strong>1<br />
P-MON-<strong>19</strong>2<br />
P-MON-<strong>19</strong>3<br />
P-MON-<strong>19</strong>4<br />
P-MON-<strong>19</strong>5<br />
P-MON-<strong>19</strong>6<br />
P-MON-<strong>19</strong>7<br />
P-MON-<strong>19</strong>8<br />
Maldi Imaging Detection Of A MRI Contrast Agent In Mouse Liver<br />
Elena Acquadro (BioIndustry Park Canavese, ITALY), Davide Corpillo, Claudia Cabella,<br />
Luigi Miragoli, Enrico Maria Bucci<br />
From Lipids To Proteins In One Single Tissue<br />
Erika Amstalden van Hove (FOM Institute for Atomic and Molecular Physics, THE<br />
NETHERLANDS), Ivo Klinkert, Tiffany Greenwood, Kristine Glunde, Ron Heeren<br />
Digital Imaging Mass Spectrometer<br />
Andreas Bamberger (Physics Institute, Albert-Ludwigs University of Freiburg,<br />
Freiburg, GERMANY), Casimir Bamberger<br />
High-Efficiency Ion Mobility Coupled MALDI MS For Tissue Imaging Of<br />
Endogenous Compounds<br />
Emmanuelle Claude, Paul Trim, Marten F Snel (Waters Corporation, UNITED KINGDOM),<br />
Malcolm Clench, Therese McKenna, James Langridge<br />
Monitoring Drug And Metabolites In Tissue Using Fticr Imaging Mass Spectrometry<br />
Shannon Cornett (Vanderbilt University, UNITED STATES), Jens Fuchser, Michael<br />
Becker, Sara L. Frapier, Paul Speir, Richard M. Caprioli<br />
MALDI-FTMS For Small Molecule Molecular Imaging Of Cancer Targets At<br />
Therapeutic Dosages<br />
Michael Easterling (Bruker Daltonics, Inc., UNITED STATES), Nathalie Agar, Claire<br />
Sauvageot, Jeffrey Agar<br />
Distribution Of Platinum Salts Evidenced By The Direct Mass Spectrometry<br />
Analyses Of Tissues<br />
Christian Larroque (IRCM/CRLC, FRANCE), Nicole Bec, Amina Bouslimani, Frederic Pinguet<br />
Imaging MS/ms And On-Tissue Protein Identification<br />
Luke MacAleese (FOM Institute for Atomic and Molecular Physics (AMOLF), THE<br />
NETHERLANDS), Erika R. Amstalden v. Hove, Jonathan Stauber, Ron M.A. Heeren<br />
Localizing Allergenic Proteins On The Surface Of Natural Latex Gloves By Ms<br />
Imaging<br />
Martina Marchetti (Vienna University of Technology, AUSTRIA), Emmanuel Raptakis,<br />
Günter Allmaier<br />
Correlating MALDI Imaging Mass Spectrometry Datasets<br />
Liam McDonnell (Leiden University Medical Center, THE NETHERLANDS), Alexandra<br />
van Remoortere, Rene van Zeijl, Andre Deelder<br />
MALDI Imaging: A Systems Approach To Understanding Embryonic Development<br />
Céline Meriaux (University of Lille 1, Laboratoire de neuroimmunologie des annélides,<br />
MALDI Imaging Team, FRANCE), Maxence Wisztorski, Jocelyne Bruand, Julien Franck,<br />
David Bonnel, Vineet Bafna, Eduardo Macagno, Michel Salzet, Isabelle Fournier<br />
MALDI-MSI Of Prostate Tissues For Detection Of Cancer And Micrometastatic Disease<br />
Lisa Cazares, Raymond Lance, Savvas Mendrinos, Michael Williams, MaryAnn Clemments,<br />
Richard Drake, O. John Semmes (Eastern Virginia Medical School, UNITED STATES)<br />
P-MON-<strong>19</strong>9<br />
Electrospray-Assisted Laser Desorption Ionization (ELDI) Mass Spectrometry<br />
For Molecular Imaging Of Heart¡BLiver And Brain Tissues<br />
Jentaie Shiea, Min-Zong Huang (National Sun Yat-Sen University, TAIWAN), Hay-Yan<br />
Wang, Li-Hua Lo<br />
82 83
P-MON-200<br />
P-MON-201<br />
P-MON-202<br />
P-MON-203<br />
P-MON-204<br />
A Combined Imaging Mass Spectrometry And MRI Study Of Nanoparticle Based<br />
Drug Delivery Systems<br />
Jonathan S. Stauber (FOM AMOLF Inst. Atomic/molecular Physics, THE NETHERLANDS),<br />
Lennaert Klerk, Glenda S. van Bochove, Klaas Nicolay, Ron M.A. Heeren<br />
Targeted Ion Mobility Imaging Mass Spectrometry : A New Tool For In Situ Identification<br />
Jonathan Stauber, Basak Kükrer Kaletaş (FOM Inst. Atomic/molecular Physics, THE<br />
NETHERLANDS), Ingrid M. van der Wiel, Marten Snel, Emmanuelle Claude, Ron M.A.<br />
Heeren<br />
Hierarchical Clustering: A New Tool For The Evaluation Of MALDI Tissue Images<br />
Sören-O Deininger (Bruker Daltonics, GERMANY), Michael Becker, Marc Gerhard,<br />
Arne Fütterer, Detlev Suckau<br />
Molecular Imaging Of Abeta Peptides In Hereditary Cerebral Hemorrhage With<br />
Amyloidosis-Dutch Type<br />
Alexandra van Remoortere (Biomolecular Mass Spectrometry Unit, LUMC, THE<br />
NETHERLANDS), René J.M. van Zeijl, Liam A. McDonnell, Marion L.C. Maat-Schieman,<br />
Ingrid M. Hegeman-Kleinn, Sjoerd G. van Duinen, Kim S. Rutgers, Silvère M. van der<br />
Maarel, André M. Deelder<br />
Proteomic Content And Spatial Definition Of Endometriosis Tissue<br />
Anni Vehmas (Turku Centre for Biotechnology, University of Turku and Ãbo Akademi<br />
University, FINLAND), Anne Rokka, Garry Corthals<br />
Organelle And Biological Membranes Proteomics<br />
P-MON-205<br />
Searching For Respiratory Biomakers On The Membrane Proteome Of A Sulphate<br />
Reducing Bacterium<br />
Maria Gabriela Almeida (REQUIMTE - Faculdade Ciencias e Tecnologia/ Escola<br />
Superior de Saude Egas Moniz, PORTUGAL), Marta R. Santos, Isabel Moura, Celia<br />
M. Silveira, Jorge Lampreia<br />
P-MON-213<br />
P-MON-214<br />
P-MON-215<br />
P-MON-216<br />
P-MON-217<br />
P-MON-218<br />
P-MON-2<strong>19</strong><br />
P-MON-220<br />
Membrane Proteomics Of Gram-Positive Bacteria By Complementary Approaches<br />
Doerte Becher (Institute for Microbiology, University Greifswald, GERMANY),<br />
Susanne Wolff, Hannes Hahne, Michael Hecker<br />
Nuclear Proteome Of Rice Under Dehydration Reveals Predicted And Unexpected<br />
Proteins<br />
Mani Kant Choudhary, Debarati Basu, Asis Datta, Niranjan Chakraborty,<br />
Subhra Chakraborty (National Institute for Plant Genome Research, INDIA)<br />
Proteomics Of Molecular Chaperones And Chaperone-Like Proteins In Bacterial<br />
Membranes<br />
Srgjan Civciristov (The University of Melbourne, Department of Biochemistry and<br />
Molecular Biology, Bio21 Institute, AUSTRALIA), Xenia Gatsos, Nicholas Williamson,<br />
Anthony Purcell, Trevor Lithgow<br />
Isolation And Evaluation Of Different Peroxisomes Subppopulations From Rat Liver<br />
Markus Islinger, Afsaneh Abdolzade-Bavil, Sven Liebler, Christoph Eckerskorn (BD<br />
Diagnostics, GERMANY), Alfred Völkl, Gerhard Weber<br />
Quantitative Proteomic Analysis Of The Nuclear Matrix In Pre-B Cells<br />
Rudolf Engelke (MPI of Immunobiology, GERMANY)<br />
Using Quantitative Proteomics To Identify Proteins Important For Melanoma<br />
Transformation<br />
Vaughan Feisst (School of Biological Sciences, The University of Auckland, NEW ZEALAND)<br />
The Mitochondrial Proteome In Healthy Aging<br />
Marco Gallo (Medical Genetics - The University of British Columbia, CANADA), Aruna<br />
Somasiri, Peter Ruzanov, Leonard Foster, Donald Riddle<br />
Polyspecific Anti-Mitocondrion Antibodies For Proteomics On In Toto Tissue Homogenates<br />
Elisabetta Gianazza (Gruppo di Studio per la Proteomica e la Struttura delle Proteine,<br />
Milano, ITALY), Emanuele Loro, Silvia Cazzola, Robin Wait, Carmen Brizio, Lodovica Vergani<br />
P-MON-206<br />
P-MON-207<br />
P-MON-208<br />
P-MON-209<br />
P-MON-210<br />
P-MON-211<br />
Analysis Of Human Erythrocyte Membrane And Cytosolic Sub-Proteomes By 2-DE<br />
Gloria Alvarez-Llamas (Department of Immunology, Fundacion Jimenez Diaz, SPAIN),<br />
Fernando de la Cuesta, Veronica M. Darde, Maria G. Barderas, Fernando Vivanco<br />
Molecular And Functional Organization Of Yeast Peroxisomal Membrane Protein<br />
Complexes<br />
Hanna Amelina (Stockholm University, Department of Biochemistry and Biophysics,<br />
SWEDEN), Susana Cristobal<br />
Spatiotemporal Proteomics Analysis Of Autophagy<br />
Jens Andersen (University of Southern Denmark, DENMARK), Joern Dengjel, Anders Kristensen,<br />
Maria Hoeyer-Hansen, Soeren Gade-Joergensen, Jakob Bunkeborg, Marja Jaattela<br />
Proteome Versus Morphology: The Golgi Apparatuses Of Rat Liver And Spermatid.<br />
Catherine Au (McGill University, CANADA), Alexander Bell, Robert Kearney, Michael<br />
Hallett, Louis Hermo, Tommy Nilsson, John Bergeron<br />
Desperately Seeking Comprehensive Membrane Proteomics<br />
Mark Baker (Australian Proteome Analysis Facility, AUSTRALIA)<br />
Identification Of Plasma Membrane Proteins Of Human Spermatozoa<br />
Kathrin Bartho (Ruhr-University Bochum, GERMANY)<br />
P-MON-221<br />
P-MON-222<br />
P-MON-223<br />
P-MON-224<br />
P-MON-225<br />
Using Organelle Proteomics For The Identification Of Novel Anti-Aging Small Molecules<br />
Alexander Goldberg (Concordia University, Biology Department, CANADA)<br />
Detecting The Phospholipid-Interacting Proteome By Photocross-Linking And<br />
Click-Chemistry<br />
Jacob Gubbens (Utrecht University, THE NETHERLANDS), Eelco Ruijter, Ben de<br />
Kruijff, Monique Slijper, Rob Liskamp, Toon de Kroon<br />
Sub-Cellular Proteomic Analysis In Breast Cancer<br />
Nora Gutierrez-Najera (National Institute of Genomic Medicine (INMEGEN), MEXICO),<br />
Angel Alvarado-Nuño, Karla Calderon-Gonzalez, Jose Luis Cruz, Santiago March,<br />
Gerardo Jimenez, Jose Luis Gallegos-Perez<br />
Membrane Protein Interactome Of The Endoplasmatic Reticulum In Yeast<br />
Linnea Hedin (Center for Biomembrane Research / Biochemistry and Biophysics,<br />
Stockholm University, SWEDEN), Ã Björklund, Susana Cristobal, Arne Elofsson<br />
Quantitative Analysis Of Respiratory Chain Complexes During Anaerobic<br />
Conditions<br />
Andreas Helbig (Utrecht University, THE NETHERLANDS), Marco JL de Groot,<br />
Renske A. van Gestel, Pascalle Daran Lapujade, Albert Heck, Monique Slijper<br />
P-MON-212<br />
The Cell Surface Protein Atlas<br />
Damaris Bausch-Fluck (NCCR Neuro Center for Proteomics, IMSB, ETH Zurich,<br />
SWITZERLAND), Andreas Hofmann, Thomas Bock, Bernd Wollscheid<br />
P-MON-226<br />
Cell Surface Proteomics Of Blood Cancer Cells<br />
Andreas Hofmann (NCCR Neuro Center for Proteomics, Institute of Molecular Systems<br />
Biology, SWITZERLAND), Thomas Bock, Damaris Bausch-Fluck, Bernd Wollscheid<br />
84 85
P-MON-227<br />
P-MON-228<br />
Characterization Of Organelles By Protein Correlation Profiling (PCP) Combined<br />
With SILAC<br />
Lis Jakobsen (Center for Experimental Bioinformatics, University of Southern<br />
Denmark, DENMARK)<br />
Dige Analysis Of Ras-Transformed Fibroblast Cell-Derived Exosomes<br />
Hong Ji (Ludwig Institute for Cancer Research, AUSTRALIA), Bow Tauro, Eugene<br />
Kapp, Robert Moritz, Justin Lim, Richard Simpson<br />
P-MON-241<br />
P-MON-242<br />
Phase Transfer Surfactant-Aided Membrane Proteomics For Human Colon Cancer<br />
Takeshi Masuda (Institute for Advanced Biosciences, Keio University, JAPAN),<br />
Yasuyuki Igarashi, Hiroyasu Esumi, Tomoyoshi Soga, Masaru Tomita, Yasushi Ishihama<br />
Towards Interaction Networks Of Peroxisomal Membrane Proteins In Yeast<br />
Silke Oeljeklaus (Medizinisches Proteom-Center, Ruhr-Universität Bochum,<br />
GERMANY), Benedikt Reinartz, Michael Kohl, Christian Stephan, Wolfgang Schliebs,<br />
Ralf Erdmann, Helmut E. Meyer, Bettina Warscheid<br />
P-MON-229<br />
P-MON-230<br />
P-MON-231<br />
P-MON-232<br />
P-MON-233<br />
P-MON-234<br />
P-MON-235<br />
The Lpi Technology – New Tools And Methods For Membrane Protein Research<br />
Anders Karlsson (Nanoxis AB, SWEDEN)<br />
A Proteomic Approach Toward Comprehensive Expression Of Liver Membrane<br />
Protein Of Hcv Infected Pakistani Population<br />
Rizma Khan (Department of Biochemistry, University of Karachi, PAKISTAN), Saadia<br />
Zahid, Afshan Wasti, MA Rahman, Nikhat Ahmed<br />
Discovery Of Jak1 Involvement In Osteoclastogenesis By Proteomics<br />
Hong-Hee Kim (Seoul National University, KOREA), Youngkyun Lee, Jeong Im Ha,<br />
Seok-Won Hyung, Hee Jung Jung, Sang Won Lee, Zang Hee Lee<br />
Effects Of Fludarabine Or Cladribine On The Plasma Membrane Proteome Of<br />
Lymphoma Cells<br />
Philippa L. Kohnke (The University of Sydney, AUSTRALIA), Ben Crossett, Richard I.<br />
Christopherson<br />
Organellar Protein Localization By Quantitative Proteomics And Novel<br />
Bioinformatics<br />
Chanchal Kumar (Max Planck Institute for Biochemistry, GERMANY), Francesca<br />
Forner, Matthias Mann<br />
Quantitative Proteomics Analysis Of Amino Acid Induced Ribosome Biogenesis<br />
Katja Malene Larsen (Center for Experimental Bioinformatics, University of<br />
Southern Denmark, DENMARK)<br />
Enrichment Of Membrane Proteins By Phase Partitioning Combined With Lectin<br />
Affinity<br />
Albert Lee (Department of Chemistry and Biomolecular Sciences, Macquarie<br />
University, AUSTRALIA), Nicolle Packer, Paul Haynes, Daniel Kolarich, Pia Jensen,<br />
Mark Baker<br />
P-MON-243<br />
P-MON-244<br />
P-MON-245<br />
P-MON-246<br />
P-MON-247<br />
P-MON-248<br />
P-MON-249<br />
Enhanced Detergent Extraction For The Membrane Proteomic Analysis In<br />
Cyanobacteria<br />
Jeehyun Oh (Korea Basic Science Institute, KOREA), Joseph Kown, Seung Il Kim,<br />
Jong-Soon Choi<br />
Mitochondrial Proteomics For Identification Of Metabolic Unbalance And Cellular<br />
Stress<br />
Johan Palmfeldt (Aarhus University Hospital / Aarhus University, DENMARK), Søren<br />
Vang, Vibeke Stenbroen, Peter Bross, Niels Gregersen<br />
Down-Regulation Of Two Outer Membrane Proteins Tsx And OmpW Is Required<br />
For Iron Homeostasis In Escherichia Coli<br />
Xuanxian Peng (Sun Yat-sen University, CHINA), Xiangmin Lin, Lina Wu, Hui Li,<br />
Sanying Wang<br />
High Definition Proteomic Analysis Of Human Monocyte-Derived Macrophages<br />
(MDM)<br />
Rita Polati (University of Verona, Dip. Scientifico e Tecnologico, ITALY), Francesca<br />
Bonini, Alessandra Maria Bossi, Domenico Girelli, Annalisa Castagna<br />
Subcellular Fractionation In A Fluidic Microsystem<br />
Anton Posch (Bio-Rad Laboratories GmbH, GERMANY), Aran Paulus, Monika<br />
Hausmann, Nancy Kunz, Martin Stelzle, Meike Moschallski, Thanh Tu Duong, Gert<br />
Blankenstein<br />
Subcellular Proteomics Of Mucin-Containing Vesicles In Goblet Cells<br />
Ana M Rodriguez-Piñeiro (Gothenburg University, SWEDEN), Malin E.V. Johansson,<br />
Gunnar C. Hansson<br />
Glucotoxicity And Pancreatic ß-Cell Dysfunction<br />
Jean-Charles Sanchez (Geneva University, SWITZERLAND)<br />
P-MON-236<br />
P-MON-237<br />
P-MON-238<br />
P-MON-239<br />
P-MON-240<br />
Efficient Method To Identify Membrane Proteins By Introduction Of Chemical<br />
And Enzyme Reaction<br />
JeongEun Lee (Department of Molecular Medicine, KyungPook National University<br />
School of Medicine, KOREA), Joshep Kwon, Pyong-Gon Moon, Hyun-Ho Hwang, Moon-<br />
Chang Baek<br />
Deciphering Phosphoinositide Signalling Pathways In Nuclei By Identifying<br />
Effector Proteins<br />
Aurelia Lewis (PROBE proteomic platform, Dept of Biomedicine, NORWAY), Magnus<br />
Arntzen, Clive D’Santos<br />
Withdrawn<br />
Withdrawn<br />
Differential Proteomic Analysis Of Colorectal Cancer-Derived Exosomes<br />
Justin WE Lim (Ludwig Institute for Cancer Research / Department of Biochemistry<br />
and Molecular Biology, University of Melbourne, AUSTRALIA), Eugene A. Kapp,<br />
Robert L. Moritz, Richard J. Simpson<br />
P-MON-250<br />
P-MON-251<br />
P-MON-252<br />
P-MON-253<br />
Proteomic Analysis Of Oxidative Damage To Mitochondrial Complex I In<br />
Parkinson’s Disease<br />
Birgit Schilling (Buck Institute for Age Research, UNITED STATES), Srinivas Bharath,<br />
Steven R. Danielson, Jason M. Held, Julie K. Andersen, Bradford W. Gibson<br />
Quantitative Surface Proteome Analysis Of Pancreatic ß-Cells By Targeted Mass<br />
Spectrometry<br />
Alexander Schmidt (Institute of Molecular Systems Biology, ETH Zurich/ Competence<br />
Center for Systems Physiology and Metabolic Diseases, SWITZERLAND), Katrin<br />
Eckhardt, Carsten Danzer, Lukas Mueller, Bernd Wollscheid, Bruno Domon, Willy<br />
Krek, Ruedi Aebersold<br />
Blue Native Page Analysis Of A Mouse Liver Microsomal Fraction<br />
Faezeh Shekari (Royan institude, IRAN), Bill Jordan, Hossein Baharvand, Ghasem<br />
Hosseini Salekdeh<br />
A Novel System For Membrane Protein Expression And Purification<br />
Wei-Wei Zhang, Li Deng, Qian Ruan, Jenny Cui, Sergey Sikora (GenWay Biotech, Inc.,<br />
UNITED STATES), Xiangming Fang<br />
86 87
P-MON-254<br />
P-MON-255<br />
P-MON-256<br />
P-MON-257<br />
P-MON-258<br />
P-MON-259<br />
P-MON-260<br />
P-MON-261<br />
P-MON-262<br />
P-MON-263<br />
P-MON-264<br />
P-MON-265<br />
P-MON-266<br />
P-MON-267<br />
Quantitative Erythrocyte Membrane Proteome Analysis With Blue-Native/Sds Page<br />
Monique Slijper (Utrecht University, THE NETHERLANDS), Renske van Gestel, Albert<br />
Heck, Gert Rijksen, Richard van Wijk, Wouter van Solinge<br />
A Quantitative Proteomic Analysis Of The Dynamic Changes In Protein Profiles<br />
Of Lipid Rafts During T-Cell Signaling<br />
Therese Solstad (The Biotechnology Centre of Oslo, NORWAY), Margarita Strozynski,<br />
Kjetil Taskén, Bernd Thiede, Knut Martin Torgersen<br />
The Escherichia Coli Periplasmic Chaperone Sura Is Required For The Biogenesis<br />
Of Specific Beta-Barrel Proteins En Route For The Outer Membrane<br />
Didier Vertommen (UCL-de Duve Institute, BELGIUM), Pauline Leverrier, Jean-Francois<br />
Collet, Natividad Ruiz, Thomas Silhavy<br />
Two Novel Membrane Extraction Procedures: Liquid And Solid Phase Based Chemistry<br />
Joerg von Hagen (Merck KGaA, GERMANY), Uwe Michelsen, Maria Wehsling,<br />
Robertus Hendriks<br />
TolC, OmpC and LamB Are Critical Outer Membrane Proteins For Tetracycline<br />
Resistance In Escherichia Coli<br />
San-ying Wang (Xiamen University, CHINA), Dan-feng Zhang, Hui Li, Zhi-ming Xiang<br />
Study Of The Mouse Olfactory Receptor-Associated Proteome<br />
Jenny Adler, Jon Barbour, Silke Oeljeklaus, Astrid Tschapek, Eva M. Neuhaus, Hann<br />
H. Hatt, Helmut E. Meyer, Bettina Warscheid (Medizinisches Proteom-Center, Ruhr-<br />
Universitaet Bochum, GERMANY)<br />
Membrane Proteome Of S.Cerevisiae Vacuoles<br />
Elena Wiederhold (University of Groningen, THE NETHERLANDS), Tejas Gandhi,<br />
Hjalmar Permentier, Rainer Breitling, Dirk Jan Slotboom, Bert Poolman<br />
Membrane Proteomics Analysis Of Solvent Tolerance In Pseudomonas Putida S12<br />
Dorien Wijte (TNO, THE NETHERLANDS)<br />
Affinity Profiling Of Adenine Nucleotide-Binding Proteins<br />
Justina Clarinda Wolters (University Groningen, THE NETHERLANDS)<br />
Altered Membrane Proteomic Signature In Human Colorectal Cancer<br />
Chien-Peng Wu, Pei-Yi Lin, Chia-Feng Tsai, Chih-Wei Chien, Chia-Li Han, Chih-Chiang<br />
Tsou, Ting-Yi Sung, Wen-Lian Hsu, Yu-Ju Chen (Institute of Chemistry, Academia<br />
Sinica, TAIWAN)<br />
Gene Expression And Proteomic Profiling Of Induced Hepatotoxicity In Mice<br />
Victor Zgoda (Institute of Biomedical Chemistry, RUSSIAN FEDERATION), O Tikhonova,<br />
A Kopylov, L Kurbatov, A Archakov<br />
Proteomics Analysis Of Human Placenta Syncytiotrophoblast Apical Membrane<br />
Qi Zhang (Deutsch Forschungsgemeinschaft GRAKO845, GERMANY)<br />
Proteomics And Phosphoproteomics Of Human Skeletal Muscle Mitochondria<br />
Xiaolu Zhao (Protein Research Group, Department of Biochemistry and Molecular<br />
Biology, University of Southern Denmark, DENMARK), Ole Nørregaard Jensen, Kurt<br />
Højlund, Martin Mogensen<br />
Exploring The Caveolae Proteome Using Disease-Related Caveolin Mutants<br />
Yuzi(Emma) Zheng (University of British Columbia, CANADA), Leonard Foster,<br />
Masayuki Numata<br />
Quantification I<br />
P-MON-268<br />
P-MON-269<br />
P-MON-270<br />
P-MON-271<br />
P-MON-272<br />
P-MON-273<br />
P-MON-274<br />
P-MON-275<br />
P-MON-276<br />
P-Mon-277<br />
P-MON-278<br />
P-MON-279<br />
P-MON-280<br />
A Workflow For Quantitative Proteomic Analysis Of siRNA-Mediated Silencing In<br />
Human Cells<br />
Albina Abdrakhmanova (Applied Biosystems, GERMANY)<br />
Quantitative Phosphorylation Analysis Method By Enzyme-Assisted And<br />
Chemical Labeling Approach<br />
Yeong Hee Ahn (Division of Mass Spectrometry, Korea Basic Science Institute, KOREA),<br />
Ji Yeon Lee, Eun Sun Ji, Kun Cho, Hyun Ju Kang, Hoguen Kim, Jong Shin Yoo<br />
Protein Expression Analysis Of A Human Osteoblast Differentiation Model<br />
Rodrigo Alves (Department of Internal Medicine, Erasmus MC, THE NETHERLANDS),<br />
Marco Eijken, Sigrid Swagemakers, Peter Burgers, Mark Titulaer, Robert-Jan Lamers,<br />
Theo Luider, Johannes van Leeuwen<br />
A New Approach For Target Peptides Quantification<br />
Je-Hyun Baek (Korea Institute of Science and Technology, KOREA), Hokeun Kim, Myeong-Hee Yu<br />
Label-Free Comparison Of Complex Protein Samples<br />
Casimir Bamberger (The Scripps Research Institutes, UNITED STATES), Sandra<br />
Pankow, Tao Xu, Sung Kyu Park, John Yates<br />
Label-Free Quantification Of Affinity-Purified Proteins: Three Complementary<br />
Approaches And Their Software Integration<br />
Alexander Haupt, Martin L. Biniossek, Wolfgang Bildl (Institute of Physiology,<br />
University of Freiburg, GERMANY), Joerg O. Thumfart, Catrin S. Mueller, Franz<br />
Jehle, Bernd Fakler, Uwe Schulte<br />
Spectral Merging To Improve Peptide Identification And Quantitation<br />
Rosa Viner, Torsten Ueckert, Terry Zhang, Vlad Zabrouskov (Thermo Fisher<br />
Scientific, UNITED STATES)<br />
Psaq Strategy For Sensitive And Accurate Quantification Of Biomarkers In<br />
Serum And Food<br />
Virginie Brun (CEA / INSERM U880 Exploring the Dynamics of Proteomes, FRANCE),<br />
Michel Jaquinod, Alain Dupuis, Vinzenz Lange, Jacques-Antoine Hennekinne, Annie<br />
Adrait, Dorothee Lebert, Jerome Garin<br />
Speeding Up Peptide Isotopic 18o-Labeling With Ultrasonic Energy<br />
Ricardo Carreira (REQUIMTE-Departamento de Química, Faculdade de Ciências e<br />
Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, PORTUGAL), Raquel<br />
Rial-Otero, Carlos Lodeiro, José Capelo<br />
Errors In Peptide Quantification Due To Variability In Ion Measurements<br />
Brian Carrillo (McGill University, CANADA), Xiaoyong Wu, Pascal Pleynet, Daniel<br />
Boismenu, Sylvie Laboissiere, Robert Nadon, Robert E. Kearney<br />
Data Quality Of Label-Free LC-MS Differential Proteome Analysis<br />
Daniel Chamrad, Wolfgang Jabs, Klaus Marquart, Barbara Sitek, Kai Stuehler, Meyer<br />
Helmut, Carsten Baessmann, Martin Blueggel (Protagen AG, Dortmund, GERMANY)<br />
Quantification Of P53 Protein In Cancer Cells Treated With Doxorubicin<br />
Sun Kyu Choi (Chung Nam national university, KOREA), Jung Ok Park, Kwang Pyo Kim,<br />
Young Hwan Kim<br />
Time-Resolved Analysis Of Tnf-Alpha Signaling By Quantitative Proteomics And<br />
Phosphoproteomics<br />
Jesper V Olsen, Chunaram Choudhary (Max Planck Institute for Biochemistry, GERMANY),<br />
Chanchal Kumar, Sonja Krüger, Gaby Sowa, Florian Gnad, Juergen Cox, Matthias Mann<br />
88 89
P-MON-281<br />
Accessing Protein Dynamics In Complex Organisms<br />
Amy Claydon (Proteomics and Functional Genomics Group, University of Liverpool,<br />
UNITED KINGDOM), Michael Thom, Nick Bond, Kathryn Lilley, Jane Hurst, Rob<br />
Beynon<br />
P-MON-294<br />
High Throughput Quantitative Analysis Of A New Biomarker To Gh Abuse Using<br />
UPLC-MS/MS<br />
Richard Kay (HFL Ltd, Newmarket, UNITED KINGDOM), Jane Roberts, Graham Ball,<br />
Cristiana Velloso, Colin Creaser, Philip Teale<br />
P-MON-282<br />
P-MON-283<br />
P-MON-284<br />
P-MON-285<br />
P-MON-286<br />
P-MON-287<br />
P-MON-288<br />
P-MON-289<br />
P-mon-290<br />
Withdrawn<br />
A New Approach To Define The Relative Contribution Of Co-Migrating Proteins<br />
To Spot Intensity In 2d-Page<br />
Maarten Dhaenens (Ghent University, BELGIUM), Sofie Vandecasteele, Dieter Deforce<br />
Elucidating Rapamycin Molecular Action By Quantitative Proteomic Analysis In<br />
Yeast<br />
Marjorie Fournier (Stowers Institute for Medical Research, UNITED STATES),<br />
Norman Pavelka, Ariel Paulson, Mihaela Sardiu, Christopher Seidel, Karin Zueckert-<br />
Gaudenz, Laurence Florens, Michael Washburn<br />
Iodine-Tagged Proteomics(Metallomics) Of Human Serum. Quantitative<br />
Iodoproteomics<br />
Tamara Garcia-Barrera (Universidad De Huelva, Spain), Elisa Gomez de las Heras,<br />
Jose Luis Gomez-Ariza<br />
Robust Protein Quantification In Mass Spectrometry<br />
Gregory Strubel, Caroline Paulus, Emeline Mery, Laurent Gerfault (Cea/Grenoble<br />
LETI/DTBS, FRANCE), Florence Ricoul, Jean-Francois Giovannelli, Pierre Grangeat<br />
8-Plex itraq Facilitated Proteomic Analysis Of Human Prostate Cancer Cells<br />
Adam Glen (Academic Urology, School of Medicine and Biomedical Science, University<br />
of Sheffield, UNITED KINGDOM), Chee Sian Gan, Freddy Hamdy, Colby Eaton, Simon<br />
Cross, Philip Wright, Ishtiaq Rehman<br />
The Ins And Outs Of 15N Labeling<br />
Joost Gouw (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />
University, THE NETHERLANDS), Bas Tops, Peter Mortensen, Albert Heck, Jeroen<br />
Krijgsveld<br />
ICPL (Isotope-coded Protein Labelling) QUADRUPLEX Technology For<br />
Quantitative Proteomics<br />
Thomas M. Halder (TopLab, GERMANY), Michael Kersten, Achim Brunner, Eva-Maria<br />
Keidel, Barbara Mueller, Josef Kellermann, Friedrich Lottspeich<br />
Quantitative Proteomic Analysis Of The Secretome During Myogenesis<br />
Jeanette Henningsen (Centre of Inflammation and Metabolism, University of<br />
Copenhagen, DENMARK)<br />
P-MON-295<br />
P-MON-296<br />
P-MON-297<br />
P-MON-298<br />
P-MON-299<br />
P-MON-300<br />
P-MON-301<br />
P-MON-302<br />
P-MON-303<br />
Protein Expression Changes In Human Neuroblastoma Cells Treated With<br />
Azaspiracid-1<br />
Ralf Kellmann (Department of Molecular Biology, The University of Bergen, NORWAY),<br />
Toril A. Groenset, Kari E. Fladmark<br />
Quantitative Synaptic Proteome Analysis In A Transgenic Migraine Mouse Model<br />
Expressing Mutated Cav.2.1 Channels<br />
Oleg Klychnikov (Biomolecular Masspectrometry Unit, Dept. Parasitology LUMC, THE<br />
NETHERLANDS), Oleg Mayboroda, Ka Wan Li, Igor Sidorov, Sabine Spijker, <strong>August</strong><br />
Smit, Rune Frants, Michel Ferrari, Andre Deelder, Arn Maagdenberg<br />
Label-Free Absolute Quantitative Analysis In Mass Spectrometry<br />
Arthur Kopylov (Institute of Biomedical Chemistry RAMS, RUSSIAN FEDERATION),<br />
V Zgoda, A Archakov<br />
The SILAC-Mouse: A New Tool For Quantitative Proteomics In Vivo<br />
Marcus Krüger (Max-Planck-Inst. for Heart and Lung Research, GERMANY), Markus<br />
Moser, Siegfried Ussar, Christian Luber, Franscesca Forner, Sara Zanivan, Sara<br />
Schmidt, Thomas Braun, Rheinhard Fässler, Matthias Mann<br />
MRM Based, Multiplexed, Absolute Quantitation Of 32 Proteins In Human Plasma<br />
Michael Kuzyk (University of Victoria - Genome BC Proteomics Centre, CANADA),<br />
Derek Smith, Tyra Cross, Juncong Yang, Angela Jackson, Darryl Hardie, Leigh<br />
Anderson, Christoph Borchers<br />
The Effect Of Heat Treatment On The Degradation Of Proteins In Brain Tissue<br />
Alastair Lang (Glasgow University, UNITED KINGDOM), Richard Goodwin, Andrew Pitt<br />
The Path To Absolute Protein Quantification Using LC-MS<br />
Jim Langridge (Waters Corporation, UNITED KINGDOM), Martha Stapels, Scott<br />
Geromanos, Hans Vissers, Hans Aerts<br />
Mesothelial Cell Stress Response To Peritoneal Dialysis Fluid<br />
Michael Lechner (Institute of Analytical Chemistry and Food Chemistry, University of<br />
Vienna, AUSTRIA), Klaus Kratochwill, Michaela Endemann, Christian Siehs, Kurt R.<br />
Herkner, Bernd Mayer, Christoph Aufricht, Andreas Rizzi<br />
Building A Repository Of Validated Mrm-Transitions For Targeted Pathway Biology<br />
Johan Lengqvist (Karolinska Biomics Center, SWEDEN), Lukas Orre, Janne Lehtiö<br />
P-MON-291<br />
Detection Frequency For Peptide Quantitation In Replicate LC-MS Runs<br />
Kosaku Shinoda, Naoyuki Sugiyama, Masaru Tomita, Yasushi Ishihama (Keio<br />
University, JAPAN)<br />
P-MON-292<br />
Differential Proteome Analysis Using Targeted Label-Free And SDS-PAGE ICPL<br />
Workflows<br />
Wolfgang Jabs, Markus Lubeck, Marina Behrens (Bruker Daltonik GmbH, GERMANY),<br />
Daniel Chamrad, Barbara Sitek, Sebastian Link, Christian Stephan, Kai Stühler,<br />
Helmut Meyer, Carsten Baessmann<br />
P-MON-293<br />
Proteomic Profiling for Human Pancreatic ß-Cell Line RNAKT-15 During Islet<br />
Formation<br />
Jonghwa Jin (Seoul National University College of Medicine, KOREA), Yup Kang,<br />
Heesook Jun, Youngsoo Kim<br />
90 91
Reagents For Proteomics<br />
Standards For Clinical Proteomics<br />
P-MON-304<br />
P-MON-305<br />
P-MON-306<br />
P-MON-307<br />
P-MON-308<br />
Withdrawn<br />
Mining Low Abundant Proteins From Congestive Heart Failure Sera Using<br />
Affinity Depletion<br />
Haiying Chen (Agilent Technologies, inc., UNITED STATES), Peter Mrozinski, Nina<br />
Zolotarjova, James Martosella<br />
Captureselect Ligands: Depletion Of Abundant Blood Proteins<br />
Frank Detmers (BAC BV, THE NETHERLANDS)<br />
DY-Maleimide Labeling: A Time Saving And Easy Handling Quantification Method<br />
Lisa Dietz (University of Heidelberg, Centre for Medical Research Mannheim,<br />
Department of Dermatology, Research Group Immunology & Proteomics,<br />
GERMANY), Patrick Pankert, Alberto Bosque, Stefanie Helm, Alberto Anel, Martina<br />
Schnoelzer, Hermann-Josef Thierse<br />
Withdrawn<br />
P-MON-3<strong>19</strong><br />
P-MON-320<br />
P-MON-321<br />
P-MON-322<br />
Proteome Analysis Of Chronic Wound Fluids Via Mudpit<br />
Caroline Chojnacki (Ruhr-University-Bochum, GERMANY)<br />
Quantitative Proteomics Plus Toponomics: Searching For Mamma Carcinoma<br />
Protein Signatures<br />
Claudia Peters, Cornelia Koy, Hans Vissers, Marc Kipping, Toralf Reimer, Michael<br />
Kreutzer, Bernd Gerber, James Langridge, Hans-Jürgen Thiesen, Michael O. Glocker<br />
(Proteome Center Rostock, University of Rostock, GERMANY)<br />
The HUPO BPP Wish List<br />
Michael Hamacher (Ruhr-Universitaet Bochum, Medizinisches Proteom-Center,<br />
GERMANY), Christian Stephan, Tanja Hardt, Martin Eisenacher, Katrin Marcus,<br />
Dominic Desiderio, Howard Gutstein, Young Mok Park, Joachim Klose, Helmut E. Meyer<br />
Statistical Analyses Of Proteomic Data For The Clinical Utility Of Protein<br />
Biomarkers<br />
Takao Kawakami (Tokyo Medical University, JAPAN), Atsushi Ogiwara<br />
P-MON-309<br />
P-MON-310<br />
P-MON-311<br />
P-MON-312<br />
P-MON-313<br />
P-MON-314<br />
P-MON-315<br />
P-MON-316<br />
P-MON-317<br />
P-MON-318<br />
Withdrawn<br />
Lys-N Metallopeptidase: A Tool For Straightforward De Novo Peptide Sequencing<br />
Albert Heck (The Netherlands Proteomics Centre, THE NETHERLANDS), Nadia<br />
Taouatas, Paul Boersema, Maarten Altelaar, Shabaz Mohammed, Madalina Drugan,<br />
Bas van Breukelen<br />
In Situ Proximity Ligation Assay For Detection Of Phosphorylated PDGFRB<br />
Malin Jarvius (Uppsala University, Molecular Medicine, SWEDEN), Irene Weibrecht,<br />
Karl-Johan Leuchowius, Ulf Landegren, Ola Söderberg<br />
Characterization Of Monoclonal Antibodies Specific For K48 Or K63 Poly-<br />
Ubiquitin Chains<br />
Jennie R. Lill (Genentech Inc, UNITED STATES), Kim Newton, Marissa Matsumoto,<br />
Ingrid E. Wertz, Donald Kirkpatrick, Vishva M. Dixit<br />
Polyclonal Antibody Generation - Correlations With Immunogen Solubility<br />
Jenny Ottosson (Royal Institute of Technology, SWEDEN), Johanna Steen, Sophia Hober<br />
Antibody Qa Pipeline For Proteomics Researchers: Nci’s Antibody<br />
Characterization Program<br />
Henry Rodriguez (National Cancer Institute/National Institutes of Health, UNITED<br />
STATES), Mehdi Mesri, Gordon Whiteley, Chris Kinsinger<br />
Complementary Immobilized Proteases And Ms/Ms Methods Improve Ptm<br />
Characterization<br />
Krystal Rampalli, Michael Rosenblatt, Marty Wilkes, Paul Haney, Roger Beringer,<br />
Andreas Huhmer, John Rogers (Thermo Scientific, UNITED STATES)<br />
Improved Protein Analysis With The New Mass Spectrometry-Compatible<br />
Surfactant<br />
Sergei Saveliev (Promega Corporation, UNITED STATES)<br />
Evaluating Proteolytic Peptide Characteristics Using Etd For De Novo Sequencing<br />
Nadia Taouatas (UU, THE NETHERLANDS), Madalina Drugan, Albert Heck, Shabaz<br />
Mohammed<br />
An Engineered Fusion Tag For Enhanced Protein Solubilization And Purification<br />
Marjeta Urh (Promega Corporation, UNITED STATES)<br />
P-MON-323<br />
P-MON-324<br />
P-MON-325<br />
P-MON-326<br />
P-MON-327<br />
P-MON-328<br />
P-MON-329<br />
P-MON-330<br />
Assessment And Development Of Proteomic Technologies For Clinical<br />
Applications In Cancer<br />
Christopher R. Kinsinger (NCI/NIH, UNITED STATES), Mehdi Mesri, Henry Rodriguez<br />
Comparative Proteomics Of The Stress Response Of Primary Omental Cells And<br />
An Immortalized Mesothelial Cell Line To Peritoneal Dialysis Fluids<br />
Klaus Kratochwill (Department of Pediatrics, Medical University of Vienna, AUSTRIA),<br />
Michael Lechner, Thorsten O. Bender, Bernd Mayer, Kurt R. Herkner, Andreas Rizzi,<br />
Christoph Aufricht<br />
Withdrawn<br />
Development Of Mass Spectrometry Protein Standards Using Sequence-Validated<br />
Human Open Reading Frames<br />
Mahbod Hajivandi, Thomas Beardslee, Carla Dhillon, Ganin Meredith, R Marshall Pope,<br />
Paul Predkiu (Invitrogen, UNITED STATES), Alexander Bell<br />
Absolute Protein Quantification And Traceability To The Si<br />
Caroline Pritchard (LGC, UNITED KINGDOM), Will Burkitt, Milena Quaglia, Cristian<br />
Arsene, Andre Henrion, Ruediger Ohlendorf, Gavin O’Connor<br />
Novel Inactivation Technology Stabilizes The In Vivo Levels Of Proteins, Peptides<br />
And Phosphorylations In Tissue Samples<br />
Marcus Svensson (Denator AB, SWEDEN), Mats Borén, Maria Fälth, Per Andrén,<br />
Per Svenningsson, Karl Sköld<br />
Proteomic Patterns Predict Acute Graft-Versus-Host Disease – An Intervention Trial<br />
Eva-Maria Weissinger (Hannover Medical School, Dept. Hematology, Hemostasis, and<br />
Oncology, GERMANY), Arnold Ganser, Eric Schiffer, Harald Mischak<br />
Proteomic Approach Of Glomerulus Microdissected From Biopsy Samples Of<br />
Human Kidney<br />
Ryo Koda (Department of Structural Pathology, Institute of Neprhology, Niigata<br />
Graduate Sc / Division of Clinical Nephrology and Rheumatology, Niigata Graduate<br />
School of Medical and Detal Sciences, JAPAN), Yutaka Yoshida, Izumi Taguchi,<br />
Masayuki Tasaki, Bo Xu, Ying Zhang, Eishin Yaoita, Ichiei Narita, Fumitake Gejyo,<br />
Tadashi Yamamoto<br />
92 93
Stem Cell Proteome Biology<br />
P-MON-331<br />
P-MON-333<br />
P-MON-334<br />
P-MON-335<br />
P-MON-336<br />
Manually Curetted Protein Chip Analysis Of Pluripotency-Associated Proteins In<br />
NIH3T3 Cells<br />
Kwang-Hyun Baek (Pochon CHA University, KOREA), Brijesh Ajjappala, Bharathi<br />
Suresh, Jae-Hwan Kim, Eung-Yoon Kim, Incheol Kang<br />
Dioxin Affects Osteoblast Differentiation From Bone Marrow Stem Cells:a<br />
Proteomic Study<br />
Donatella Carpi (Istituto di Ricerche farmacologiche Mario Negri, ITALY), Merja<br />
Korkalainen, Luisa Airoldi, Roberto Fanelli, Juha Tuukkannen, Matti Viluksela, Roberta<br />
Pastorelli<br />
A Proteomics Strategy To Detect Betai Pkc Substrates In Embryonic Stem Cells<br />
Helio Costa-Juinor (Laboratory of Genetics and Molecular Cardiology Heart Institute<br />
InCor-HCFMUSP, BRAZIL), Jose Eduardo Krieger, Daria Mochly-Rosen, Deborah<br />
Schechtman<br />
Withdrawn<br />
G-CSF Stimulates Expression Of Non-Phosphorylated Stathmin In Hematopoietic<br />
Stem Cells<br />
Thomas Franz (European Molecular Biology Laboratory, GERMANY), Volker Eckstein,<br />
Xinping Li, Stefan Leicht, Rainer Saffrich, Heinrich Lannert<br />
P-MON-343<br />
P-MON-344<br />
P-MON-345<br />
P-MON-346<br />
P-MON-347<br />
Proteomic Analysis Of Tumorigenic And Non-Tumorigenic Liver Cancer Cells<br />
Isolated From Huh-7 Cell Line<br />
Eun-Kyung Lee (Korea University, KOREA), Gi-Yeon Han, Mi-Ryung Kim, Hye Won<br />
Park, Chan-Wha Kim<br />
Quantification Of Early Signaling Events In Embryonic Stem Cell Self-Renewal<br />
Yu Lu, Scott B. Ficarro, Yi Zhang, Manor Askenazi, Elzbieta Hyatt, Leah Boyer,<br />
Thorsten Schlaeger, Chance John Luckey, Jarrod A. Marto (Department of Cancer<br />
Biology, Dana-Farber Cancer Institute / Department of Biological Chemistry and<br />
Molecular Pharmocology, Harvard Medical School, UNITED STATES)<br />
Proteomic Characterization Of Circulating Human Vascular Progenitors<br />
Ursula Mayr (Cardiovascular Division, King’s College London, UNITED KINGDOM),<br />
David Simper, Xiaoke Yin, Carmen Urbich, Anna Zampetaki, Marianna Prokopi,<br />
Michael Mueller, Ulli Benbow, Robin Wait, Manuel Mayr<br />
Identification Of New Cell Surface Markers For Human Neural Stem/Progenitor<br />
Cells<br />
Aavo-Valdur Mikelsaar (Institute of General and Molecular Pathology, University of<br />
Tartu/ LabAs Ltd, ESTONIA), Alar Sünter, Peeter Toomik, Kalmer Karpson, Erkki<br />
Juronen<br />
Phosphorylation Dynamics During Differentiation Of Embryonic Stem Cells<br />
Javier Munoz (Utrecht University, THE NETHERLANDS)<br />
P-MON-337<br />
P-MON-338<br />
P-MON-339<br />
P-MON-340<br />
P-MON-341<br />
P-MON-342<br />
Quantative Proteomics Analysis Of Down Syndrome Using Mouse Es Cell Model<br />
William Griffiths (School of Medicine, Swansea University, UNITED KINGDOM), Yuqin<br />
Wang, Dean Nizetic, Jurgen Groet<br />
Pr<strong>event</strong>ion Of Amino Acid Conversion In Silac Experiments With Embryonic<br />
Stem Cells<br />
Christopher Hughes (University of Western Ontario, CANADA), Sean Bendall, Gilles<br />
Lajoie<br />
The Effect Of Low Glucose On Human Bone Marrow Derived Mesenchymal Stem<br />
Cells<br />
Bo Ram Ji (KOREA University, KOREA), Ji Soo Kim, Mi Ryong Kim, Hye Won Park,<br />
Chan Wha Kim<br />
Comparative Analysis Of Secretome Of Adipose-Derived Stem Cells During<br />
Adipogenesis<br />
Jaeyoon Kim (Division of Molecular and Life Science, Pohang University of Science<br />
and Technology, KOREA), Yoon Sup Choi, Jae-Ho Kim, Pann-Ghill Suh, Sung Ho Ryu,<br />
Taehoon G. Lee<br />
Depot Specific Proliferation-Related Proteins In Bovine Adipose Stromal<br />
Vascular Cells<br />
Seulmina Kwon (National Institute of Animal Science, KOREA), Sujin Park, Mirim<br />
Park, Enjung Jang, Mina Park, Ssanggoo Cho, Dongwoon Kim, sunggoo Hong,<br />
Hyunjung Lee<br />
Application Of A Iterative Exclusion (IE)-MS Analysis to Human Embryonic Stem<br />
Cells<br />
Gilles Lajoie (University of Western Ontario, CANADA), Sean Bendall, Chris Hughes,<br />
Mickie Bhatia, Morag Stewart<br />
P-MON-348<br />
P-MON-349<br />
P-MON-350<br />
P-MON-351<br />
P-MON-352<br />
P-MON-353<br />
Proteomic Analysis Of The Effects Of Bmp4 Exposure On Human Embryonic<br />
Stem Cells<br />
Gilbert Omenn (University of Michigan, UNITED STATES), Anastasia Yocum, Theresa<br />
Gratsch, Nancy Leff, John Strahler, Angela Walker, George Michailidis, K Sue<br />
O’Shea, Philip Andrews<br />
Proteomic Analysis Of Bovine Muscle Satellite Cells During Adipogenic<br />
Differentiation<br />
Mi-Rim Park (National Livestock Research Institute, KOREA), Su-Jin Park, Seulmina<br />
Kwon, Eung-Jung Jang, Dong-Woon Kim, Hyun-Jung Lee<br />
Integrated Approach To Study Protein Expression In Mouse Embryonic Stem Cells<br />
KS Setty Rakesh, Minoru S.H. Ko, Dawood Dudekula, Ramaiah Nagaraja,<br />
Ravi Sirdeshmukh (Centre for Cellular and Molecular Biology, INDIA)<br />
Comparative Proteome And Transcriptome Analysis Of Human, Mouse, And<br />
Monkey Escs During Differentiation<br />
Ghasem Salekdeh (Royan Institute, IRAN)<br />
Studies Of Krab Znf Genes Differentially Expressed In Induced Pluripotent Stem<br />
Cells (IPS)<br />
Hans-Juergen Thiesen (Institute of Immunology, University of Rostock, GERMANY),<br />
Peter Lorenz, Michael Kreutzer, Cristina Al-Khalili Szigyarto, Matthias Uhlén, Guohui<br />
Ding, Yixue Li<br />
Comparative Transcriptomics And Proteomics Of Fetal And Adult Human Liver<br />
Konstantin Yarygin (Institute of Biomedical Chemistry RAMS, RUSSIAN<br />
FEDERATION), I Cheglakov, L Kurbatov, I Toropygin, A Archakov, G Sukhikh, G<br />
Vartanian<br />
94 95
Structural Proteomics<br />
P-MON-354<br />
P-MON-355<br />
P-MON-356<br />
Characterization Of The Fc And Fab Parts Of Recombinant- And Plasma Derived<br />
Polyclonal- Antibodies By MALDI Mass Spectrometry<br />
Omar Belgacem (Shimadzu Biotech, UNITED KINGDOM), Emmanuel Raptakis, Gerald<br />
Stubiger, Andrea Buchacher, Katharina Pock<br />
Cross-Linking Analysis Of Affinity-Purified Multi-Protein Complexes<br />
Zhuo Chen (University of Edinburgh, UNITED KINGDOM), Morten Rasmussen, Salman<br />
Tahir, Sjaak van der Sar, Kevin G. Hardwick, Juri Rappsilber<br />
Effects Of Low Ph On Amyloid-Fibrillation Of A Beta2-Microglobulin Variant<br />
Dorthe Corlin (Statens Serum Institut, DENMARK)<br />
P-MON-368<br />
P-MON-369<br />
P-MON-370<br />
Specific Enrichment Of Cross-Linked Peptides From Complex Mixtures<br />
Lau Sennels (Wellcome Trust Centre for Cell Biology, University of Edinburgh,<br />
UNITED KINGDOM), Adam Belsom, Mark Bradley, Juri Rappsilber<br />
Membrane Topology Of Monotopic Proteins: Shaving Off Biological Membranes<br />
Illarion Turko (Center for Advanced Research in Biotechnology, UNITED STATES),<br />
Natalia Mast, Wei-Li Liao, Irina Pikuleva<br />
Software Supported Top-Down Protein Sequence Characterization And<br />
Assignment Of Termini<br />
Lars Vorwerg, Anja Resemann (Bruker Daltonik GmbH, GERMANY), Detlev Suckau<br />
P-MON-357<br />
P-MON-358<br />
P-MON-359<br />
P-MON-360<br />
P-MON-361<br />
P-MON-362<br />
P-MON-363<br />
P-MON-364<br />
P-MON-365<br />
P-MON-366<br />
P-MON-367<br />
Contribution Of Human Telomerase Processivity To Telomere Length Maintenance<br />
Yasmin D’Souza (Lady Davis Institute, Jewish General Hospital, CANADA), Sophie<br />
Dupuis, Chantal Autexier<br />
Surface Mapping Of Human Cystathionine Beta-Synthase By Chemical<br />
Modification Of Amino Acids<br />
Ales Hnizda (Institution of metabolic disorder, 1st Medical Faculty, CZECH REPUBLIC),<br />
Viktor Kozich<br />
Rapid Assignment Of Disulfide Linked Peptides Utilizing Automatic A1 Ion Screening<br />
Sheng Yu Huang (Life Science business unit, C Sun MFG. LTD., TAIWAN), Chien Hsien<br />
Wen, Ding Tzai Li, Fong Ku Shi<br />
Caveolar Traffic Of Birch Pollen Allergen Bet V 1 Through Nasal Epithelium In<br />
Allergic Patients<br />
Risto Renkonen (Haartman Institute, University of Helsinki, FINLAND), Sakari<br />
Joenväärä, Pirkko Mattila, Antti Mäkitie, Sanna Salmi, Jutta Renkonen<br />
IMGT Colliers De Perles For Standardized Analysis Of V, C And G Type Domains<br />
François Ehrenmann (IMGT, the international ImMunoGeneTics information system,<br />
FRANCE)<br />
Conformational Changes In The P22 Portal Observed By Mass Spectrometry<br />
Kristina Lorenzen (UU, THE NETHERLANDS)<br />
Beyond Bottlenecks In Membrane Protein Overproduction In Lactococcus Lactis<br />
Ravi Kanth Reddy Marreddy (University of Groningen, THE NETHERLANDS), Joao<br />
P.C. Pinto, Eric R. Geertsma, Jan Kok, Bert Poolman<br />
Monitoring Protein Interactions By Bimolecular Fluorescence Complementation<br />
And Flow Cytometry<br />
Montserrat Morell (Institut Biotecnologia i Biomedicina - UAB, SPAIN), Alba<br />
Espargaro, Francesc Xavier Aviles, Salvador Ventura<br />
Novel Reagents For Structural Proteomics Crosslinking Applications<br />
Evgeniy Petrotchenko (UVic-Genome BC Proteomics Center, CANADA), Jamie Thomas,<br />
Christoph Borchers<br />
Profiling A Proteome For Hyperstable Proteins And Cellular Processes<br />
Vesna Prosinecki (Instituto Tecnologia Química e Biológica, Universidade Nova de<br />
Lisboa, PORTUGAL), Trong Khoa Pham, Phillip C. Wright, Claudio M. Gomes<br />
Identification Of Cross-Linked Peptides In Proteomic-Scale Experiments<br />
Juri Rappsilber (University of Edinburgh, UNITED KINGDOM), Morten Rasmussen,<br />
Salman Tahir, Zhuo Chen<br />
96 97
Poster Listing<br />
<strong>Tuesday</strong> <strong>19</strong> august<br />
Alternative Splicing & Protein Processing<br />
P-TUE-001<br />
P-TUE-002<br />
P-TUE-003<br />
P-TUE-004<br />
P-TUE-005<br />
P-TUE-006<br />
P-TUE-007<br />
P-TUE-008<br />
P-TUE-009<br />
P-TUE-010<br />
P-TUE-011<br />
P-TUE-012<br />
Search For Protein Over-Expression In Micro-Organisms Using Proteomics Tools<br />
Michiel Akeroyd (Dsm, THE NETHERLANDS)<br />
Protein N-Alpha-Acetylation Analyzed By N-Terminal Cofradic<br />
Thomas Arnesen (University of Bergen, NORWAY), Petra van Damme, Bogdan<br />
Polevoda, Kenny Helsens, Rune Evjenth, Jan Erik Varhaug, Joël Vandekerckhove,<br />
Johan R. Lillehaug, Fred Sherman, Kris Gevaert<br />
Withdrawn<br />
The Ligandome Of Non-Classical Mhc On Tumor Escape Variants<br />
Arnoud de Ru (Lumc, THE NETHERLANDS), Bianca Querido, Frits Koning, Thorbald<br />
van Hall, Peter van Veelen<br />
Isolation Of Protein Isoforms By Free Flow Electrophoresis Preserving Biological<br />
Activity<br />
Afsaneh Abdolzade-Bavil (Bd Diagnostics, GERMANY), Christian Obermaier, Siegfied<br />
Hirler, Ute Sukop, Gerhard Weber, Mikkel Nissum, Christoph Eckerskorn<br />
Alternative Splicing Of Tissue Factor And enos In Tnf-á Stimulated Human<br />
Endothelial Cells<br />
Andreas Eisenreich (Charitè – Universitätsmedizin Berlin, Campus Benjamin Franklin,<br />
Centrum Für Herz- Und Kreislaufmedizin, GERMANY), Vladimir Bogdanov, Heinz-<br />
Peter Schultheiss, Ursula Rauch<br />
Ppr: The Protein Processing Resource<br />
Niklaas Colaert (Department of Medical Protein Research / Department of<br />
Biochemistry, Ghent University, BELGIUM), Lennart Martens, Joël Vandekerckhove,<br />
Kris Gevaert<br />
The Human Protein Atlas - A Resource For Discovery And Validation Of<br />
Biomarkers<br />
Caroline Kampf (Uppsala University, SWEDEN), Anna Asplund, Kenneth Wester,<br />
Mathias Uhlén, Fredrik Ponten<br />
Further Improvement Of A Novel Method For C-Terminal Sequence Analysis In<br />
The Proteomic Era<br />
Pablo Moerman (Ghent University, BELGIUM)<br />
Comparison Of Secreted Protein Expression From Hepg2 Cells Exposed To<br />
2,3,7,8-Tetrachlorodibenzo-P-Dioxin And 2,3,4,7,8-Pentachloro Dibenzofuran<br />
Sohee Phark (KOREA University, KOREA), Seonyoung Choi, Zhi Zheng, Eunkyoung Jo,<br />
Min Lee, So-Young Park, Donggeun Sul<br />
Recipes For Resolved Electrophoresis Gels From Pure Chemicals<br />
Naziha Chirani (Université Des Sciences Et Technologies De Lille, FRANCE), Caroline<br />
Tokarski, Christian Rolando<br />
Targeted Analysis Of Protein Termini<br />
Bas van Breukelen (Uu, THE NETHERLANDS), Wilma Dormeyer, Shabaz Mohammed,<br />
Jeroen Krijgsveld, Albert Heck<br />
P-TUE-013<br />
P-TUE-014<br />
Biomarkers Ii<br />
P-TUE-015<br />
P-TUE-016<br />
P-TUE-017<br />
P-TUE-018<br />
P-TUE-0<strong>19</strong><br />
P-TUE-020<br />
P-tue-021<br />
P-TUE-022<br />
P-TUE-023<br />
P-TUE-024<br />
P-TUE-025<br />
A Proteomics Approach To Identification Of Minor Histocompatibility Antigens<br />
Peter van Veelen (Lumc, THE NETHERLANDS), Michel Kester, Kees van Bergen,<br />
Frits Koning, Harm Nijveen, Jack Leunissen, Arnoud de Ru<br />
Quantitative Glyco-Proteomics Detects Macrophage Release Of Inflammatory<br />
Mediators Following Activation<br />
Wei Yan, Ivan Gomez, Zhiyuan Hu, Hamid Mirzaei, Alexander Schmidt, Elaine Raines,<br />
Reudi Abersold (Institute For Systems Biology, UNITED STATES / Institute of<br />
Molecular Systems Biology / Faculty of Science, University of Zurich, SWITZERLAND)<br />
The Comprehensive Proteomic Analyses For The Discovery Of Novel Markers Of<br />
Alcohol Abuse<br />
Fumio Nomura (Department of Molecular Diagnosis, Graduate School of Medicine,<br />
Chiba University, Division of Laboratory Medicine, Clinical Genetics and Proteomics,<br />
Chiba University Hospital, JAPAN), Kazuyuki Sogawa, Takeshi Tomonaga, Yoshio<br />
Kodera, Tadakazu Maeda<br />
Isolation Of Low Molecular Weight Protein In Vitreous Humor Using A Protein<br />
Separator<br />
Haru Okamoto (National Tokyo Medical Center, JAPAN), Hiroyuki Shimada, Kiyoshi<br />
Matsuno, Kazuhiro Tanahashi, Jun Utsumi, Takeshi Iwata<br />
Withdrawn<br />
Withdrawn<br />
Unipep - A Resource For Targeted Biomarker Evaluation In Human Plasma And<br />
Tissue Samples<br />
Reto Ossola (Institute of Molecular Systemsbiology, SWITZERLAND), Johan<br />
Malmstroem, Dave Campbell, Kelly Cooke, Alexander Schmidt, Lars Malmstroem,<br />
Julian Watts, Ruedi Aebersold, Bruno Domon<br />
The Number, Composition, And Autoimmunity Of Circulating Microparticles In<br />
Rheumatoid Arthritis And Systemic Lupus Erythematosus<br />
Ole Østergaard (Statens Serum InsTitut, DENMARK), Christoffer T. Nielsen, Lone<br />
Troelsen, Martin R. Larsen, Søren Jacobsen, Niels Heegaard<br />
Identification Of Hsp 27 As Methylglyoxal Target In Colon Mucosa Of Ulcerative<br />
Colitis<br />
Tomoko Oya-Ito (Department of Medical Proteomics, Kyoto Prefectural University<br />
of Medicine, JAPAN), Yuji Naito, Tomohisa Takagi, Osamu Handa, Hirofumi Matsui,<br />
Toshikazu Yoshikawa<br />
Withdrawn<br />
Depot Specific Expressions Of Proliferation-Related Proteins In Bovine Satellite Cells<br />
Soo-Jin Park (National Institute of Animal Science, KOREA), Seulmina Kwon, Eun<br />
Jung Jang, Mi-Rim Park, Dong-Woon Kim, Seung-Gu Hong, Hyun-JeonG Lee<br />
Elevation Of Complement Component 3 In The Blood Of Autistic Patients<br />
Traci Pawlowski (Translational Genomics Research Institute (Tgen), UNITED<br />
STATES), April Allen, Jason Corneveaux, Jennifer Webster, Dietrich Stephan,<br />
Christopher Smith, Sarah Brautigam, Janet Kirwin, Matthew Huentelman<br />
Identifying Predictive Biomarkers Of Gastric Cancer Using Ms Profiling And 2-D Dige<br />
Megan Penno (Adelaide Proteomics Centre, University of Adelaide, AUSTRALIA),<br />
Matthias Ernst, Peter Hoffmann<br />
98 99
P-TUE-026<br />
P-TUE-027<br />
P-TUE-028<br />
P-TUE-029<br />
P-TUE-030<br />
P-TUE-031<br />
P-TUE-032<br />
P-TUE-033<br />
P-TUE-034<br />
P-TUE-035<br />
P-TUE-036<br />
P-TUE-037<br />
P-TUE-038<br />
P-TUE-039<br />
P-TUE-040<br />
Plasma Biomarker Discovery In Hepatocellular Carcinoma- A Pilot Case-Control<br />
Study In The Gambia<br />
Amelie Plymoth (International Agency for Research on Cancer, FRANCE), Pierre<br />
Hainaut, Laura Beretta<br />
Effects Of Organophosphates On Peptide Fraction Of Human Blood Serum<br />
Ekaterina Podolskaya (Institute for Analytical Instrumentation, Ras, RUSSIAN<br />
FEDERATION), Vladimir Babakov, Nikolay Goncharov, Lidia Glashkina, Elena Ermolaeva,<br />
Dariya Prokof’eva, Iliya Krasnov, Nikita Polyakov, Andrey RadiLov, Nikolay Krasnov<br />
Proteome Analysis Of Lung Squamous Cell Carcinoma Tissue Reveals Hsp47 And<br />
Cytokeratins As Potential Biomarkers<br />
Gereon Poschmann (Ruhr-Universität Bochum, GERMANY), Bence Sipos, Anna<br />
Ulrich, Christian Stefan, Bettina Warscheid, Guenther Kloeppel, Ann Vander Borght,<br />
Frans Ramaekers, Helmut E. Meyer, Kai Stuehler<br />
Potential Biomarkers For Early Detection Of Graft-Versus-Host Disease<br />
Alexandra Kaplanova, Ondrej Sedo, Hana Konecna, Sarka Pospisilova (Center of Molecular<br />
Biology and Gene Therapy, Department of Internal Medicine - Hematooncology, Medical<br />
Faculty Mu and University Hospital Brno, CZECH REPUBLIC), Jiri Mayer, Zbynek Zdrahal<br />
Characterization Of Ptms Of Ttr In Csf From Dementia Patients And Controls<br />
By Ia-Ms<br />
Keld Poulsen (Statens Serum Institut, DENMARK), Justyna Bahl, Martin Larsem,<br />
Niels Heegaard<br />
Sample Preparation For The Proteomic Analysis Of The Lung Biofluids<br />
Anne Puustinen (Finnish Institute of Occupational Health, FINLAND)<br />
Urine Peptidomics With Lc-Ms<br />
Suvi Ravela (Clinical Chemistry, University of Helsinki, FINLAND), Sakari Joenväärä,<br />
Risto Renkonen, Ulf-Håkan Stenman, Leena Valmu<br />
Plasma Protein Profiles In Early Asthmatic Responses To Inhalation Allergen Challenge<br />
Taiyoun Rhim (Soonchunhyang University Hospital, KOREA), Yun-Sung Choi, Bo-Young<br />
Nam, Soo Taek Uh, Jongsook Park, Yong Hoon Kim, Choon-Sik Park<br />
Study Of Protein Biomarker For Diabetes Type 2 In Local Population<br />
Samreen Riaz (Microbiology & Molecualr Genetics Dept, Punjab Univesrity, Lahore,<br />
PAKISTAN), Saadia Shahzad Alam, M Waheed Akhtar<br />
Identification Of Serum Candidate Biomarkers By 2-De And Maldi Tof/Tof Ms<br />
Maria Stella Ritorto (Fraunhofer Item, GERMANY), Juergen Borlak<br />
Secretome Analysis Of Human Primary Fibroblasts Undergoing Senescence<br />
Adelina Rogowska-Wrzesinska (University of Southern Denmark, DENMARK), Lucia<br />
Miciutkowa, Thomas Diener, Chen Li, Rong Zeng, Pidder Jansen-Dürr, Peter Roepstorff<br />
Correlation Of Proteomics And Clinical Data Of Patients With Chronic<br />
Lymphocytic Leukemia<br />
Jose Cesar Rosa (Fmrp - University of Sao Paulo, BRAZIL)<br />
Withdrawn<br />
Search For Multiple Sclerosis Proteomic Biomarkers In Cerebrospinal Fluid By<br />
Chiplc-Ms<br />
Therese Rosenling (University of Groningen, THE NETHERLANDS)<br />
Sensitive And Fast Hepcidin Quantitation From Crude Urine With Maldi Ms<br />
Udo Roth, Christoph Menzel (Qiagen GmbH, GERMANY), Christian Feckler, Kerstin Steinert<br />
C. Elegans And Drosophila<br />
P-TUE-041<br />
P-TUE-042<br />
P-TUE-043<br />
P-TUE-044<br />
P-TUE-045<br />
P-TUE-046<br />
P-TUE-047<br />
O-Linked N-Acetylglucosamine Modification Regulates Dauer Entry In<br />
Caenorhabditis Elegans<br />
Kwang Youl Kim (Department of Biochemistry, Yonsei University, KOREA), Jeeyong<br />
Lee, Jihyun Lee, Young-Ki Paik<br />
Withdrawn<br />
Identification Of Phosphorylcholine Substituted Proteins In Caenorhabditis Elegans<br />
Julia Grabitzki, Michael Ahrend, Rudolf Geyer, Guenter Lochnit (Institute of<br />
Biochemistry, University Giessen, GERMANY)<br />
Proteomic Studies Of Lepidoptera<br />
Susanne Preiss (Max Planck Institute for Chemical Ecology, GERMANY), Yannick<br />
Pauchet, Juliette Courtiade, David Heckel<br />
Comparative Functional Analysis Of The Caenorhabditis Elegans And Drosophila<br />
Melanogaster Proteomes<br />
Sabine Schrimpf (University of Zurich; Institute of Molecular Biology,<br />
SWITZERLAND), Manuel Weiss, Lukas Reiter, Christian Ahrens, Marko Jovanovic,<br />
Johan Malmström<br />
Withdrawn<br />
Pressure-Mediated Sample Preparation Methods For Isolating Proteins From<br />
Caenorhabditis Elegans<br />
Gary Smejkal (Pressure Biosciences, UNITED STATES), Jobriah Anderson, W Kelley<br />
Thomas, Ada Kwan, Greta Carlson, Vera Gross, Alexander Lazarev<br />
P-TUE-048 Involvement Of Nucleotidyl Transferases In Rnai And Germline Viability In C.<br />
Elegans<br />
Josien van Wolfswinkel (Utrecht University, Dept of Biomolecular Mass<br />
Spectrometry / Hubrecht Institute, Dept of Rna Silencing, THE NETHERLANDS),<br />
Jeroen Krijgsveld, Abby Dernburg, Albert Heck, Rene Ketting<br />
Cancer Related Signaling<br />
P-TUE-049<br />
P-TUE-050<br />
P-TUE-051<br />
P-TUE-052<br />
Modified Tumor Cell Protein Expression And Modification Under Physiological Oxygen<br />
Tamara Nyberg (Molecular Probes-Invitrogen, UNITED STATES), Kondala Atkuri,<br />
Courtenay Hart, Kurosh Ameri, Brian Agnew<br />
Differential Protein Expression In Activated E2f2-/- T Lymphocyte Non-Cytosolic<br />
Fraction<br />
Mikel Azkargorta (Department of Biochemistry and Molecular Biology, University of<br />
The Basque Country, SPAIN), Kerman Aloria, Ana Zubiaga, Jesus Mari Arizmendi,<br />
Asier Fullaondo<br />
Systemic Analysis Of Tgf β; Proteomics Revealed Involvement Of Plag1/Cnk1/<br />
Rassf1a/Src Network In Tgf β;1-Dependent Activation Of Erk1/2 And Cell<br />
Proliferation<br />
Nimesh Bhaskaran (Karolinska Biomics Center, Department of Oncology-Pathology,<br />
Karolinska Institutet, Karolinska University Hospital, SWEDEN), Serhiy Souchelnytskyi<br />
Detection Of Protein Signatures Associated With Tumor Cell Dissemination In<br />
Oral Cancer<br />
Onno Bleijerveld (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />
University, THE NETHERLANDS), Ruud Brakenhoff, Mirjam Damen, Maarten Altelaar,<br />
Albert Heck, Rene Leemans, Monique Slijper<br />
100 101
P-TUE-053<br />
P-TUE-054<br />
P-TUE-055<br />
Induction Of Apoptosis In Jeko-1 Mantle Cell Lymphoma Cell Line By Resveratrol:<br />
A Proteomic Analysis<br />
Daniela Cecconi (University of Verona, Dip. Scientifico e Tecnologico, Laboratorio di<br />
Proteomica, ITALY), Alberto Zamò, Alice Parisi, Elena Bianchi, Claudia Parolini, Anna<br />
Maria Timperio<br />
Differentially Expressed Phosphorylated Proteins In Gastrointestinal Stromal<br />
Tumors According To Kit And Pdgfra Mutation<br />
Hee-Jung Choi (Department of Pathology / Brain Korea 21 Project for Medical<br />
Sciences, Yonsei University College of Medicine, KOREA), Hyun Ju Kang, Hanna Lee,<br />
Yeong Hee Ahn, Jong Shin Yoo, Hoguen Kim<br />
Proteome Analysis Of Human Ovarian Cancer Cells To Identify Tubb3 Protein<br />
Complexes<br />
Lucia Cicchillitti (“John Paul Ii ” Centre for High Technology Research and Education<br />
in Biomedical Sciences, Catholic University, Campobasso, ITALY)<br />
P-TUE-065<br />
P-TUE-066<br />
P-TUE-067<br />
P-TUE-068<br />
Functional Proteomics: Bisphenol A Disrupts The Mammary Proteome<br />
Sarah Jenkins (University of Alabama at Birmingham, Department of Pharmacology<br />
& Toxicology, UNITED STATES), Nandini Raghuraman, Coral Lamartiniere<br />
Dynamics Of Protein Nitration In The Cell Cycle<br />
Min Jia (Karolinska Biomics Center, THE NETHERLANDS)<br />
Combining Formaldehyde-Based Affinity Enrichment And Global Silac To Study<br />
Cdc42 Activity<br />
Juergen Kast (University of British Columbia, CANADA), Brent W. Sutherland<br />
Non-Histone Nuclear Factor Hmgb1 Is Secreted Through The Nuclear Pkc-Δ<br />
Mediated Phosphorylation<br />
Hanna Lee, Hyun Ju Kang, Hee-Jung Choi, Yeong-Hee Ahn, Hoguen Kim (Department<br />
of Pathology / Brain Korea 21 Project for Medical Sciences, Yonsei University College<br />
of Medicine, KOREA)<br />
P-TUE-056<br />
P-TUE-057<br />
AnaLysis Of Trail Resistance In Human Melanoma Cells Using Dige<br />
Ben Crossett (University of Sydney, AUSTRALIA), Eva Yang, Xu Dong Zhang, Peter<br />
Hersey, Richard Christopherson<br />
Proteome Profiling Of Neuroblastoma Resistant Cell Line By 2de And Label-Free<br />
Lc-Ms<br />
Simona D’aguanno (Dipartimento di Medicina Interna Università di Tor Vergata Rome/<br />
Irccs-Fondazione Santa Lucia Centro di Ricerca Sul Cervello, ITALY), Annamaria<br />
D’alessandro, Luisa Pieroni, Sergio Bernardini, Giorgio Federici, Andrea Urbani<br />
P-TUE-069<br />
P-TUE-070<br />
Subnuclear Proteomics Through Differential Extraction Of Colorectal Cancer<br />
Tissue<br />
Jakob Albrethsen, Jaco Knol (Oncoproteomics Laboratory, VUmc-Cancer Center<br />
Amsterdam, THE NETHERLANDS), Sander Piersma, Meike de Wit, Sandra Mongera,<br />
Beatriz Carvalho, Gerrit Meijer, Connie Jimenez<br />
Interaction Of The Corepressor Alien With E2f/Rb Pathway<br />
Robert Kob (Institute of Human Genetics and Anthropology, GERMANY), Juliane<br />
Kelm, Aria Baniahmad, Ferdinand von Eggeling, Christian Melle<br />
P-TUE-058<br />
P-TUE-059<br />
P-TUE-060<br />
The Proteomic Analysis Of B Cell Signaling In Chronic Lymphocytic Leukaemia<br />
Gina Eagle (Cancer Biology Proteomics Group, Post Graduate Medical Institute<br />
of the University of Hull in Association with the Hull York Medical School, UNITED<br />
KINGDOM), David Allsup, Lynn Cawkwell<br />
New Functions Of P16ink4a Using A Proteomic Approach<br />
Josep M. Estanyol (University Of Barcelona, SPAIN)<br />
Protein And Peptide Profiling Of Fresh Human Breast Cancer Tumours<br />
Christina Greenwood (Helen RollaSon Heal Cancer Research Laboratory, Anglia<br />
Ruskin University, UNITED KINGDOM), Gergana Metodieva, Louise Alldridge, Laura<br />
Thwaites, Khalid Al-Janabi, Metodi Metodiev<br />
P-TUE-071<br />
P-TUE-072<br />
P-TUE-073<br />
Human Prostate Cancer Progression: A Complete Proteomic Analysis<br />
John Lapek (Proteomics Center, University of Rochester, UNITED STATES), Lauren<br />
Jensen, William Ricke, Alan Friedman<br />
Use Of Peptide Ief-Lc-Ms/Ms Reveals Proteome Components Involved In Lung<br />
Cancer Therapy Response<br />
Janne Lehtiö (Karolinska Institutet, SWEDEN), Lukas Orre, Johan Lengqvist, Hanna<br />
Eriksson, Bengt Persson, Per-Johan Jakobsson, Rolf Lewensohn<br />
Proteomics Approaches For Studying Molecular Mechanism Of Invasion Of Highly<br />
Invasive Clones Of Mcf-7 Human Breast Carcinoma<br />
Kah-Wai Lin (Karolinska Biomics Center, SWEDEN), Serhiy Souchelnytskyi<br />
P-TUE-061<br />
P-TUE-062<br />
P-TUE-063<br />
P-TUE-064<br />
Whole-Celss Proteome Analysis Of The Mtor Signaling Using 2d Digest-Lc-Ms/<br />
Ms And Index-T<br />
Sang Hoon Ha (Sigmol Inc., KOREA), Yoen-Young Yoo, Pann-Ghill Suh, Sung Ho Ryu,<br />
Taehoon Lee<br />
Target Proteins Of Lps-Stimulated Lipid Accumulation Regulated By Thiol-<br />
Antioxidant Thioredoxin<br />
Gi-Yeon Han (Korea University, KOREA), Eun-KYung Lee, Hye-Won Park, Hyun-Ji Lee,<br />
Eun-Jeong So, Won-A Joo, Yoon-Ha Kim, Jun-Seop Shin, Mi-Ryung Kim, Chan-Wha<br />
Kim<br />
Effects Of Microenvironment On Tumor Growth: A Comparative Proteomics<br />
Approach<br />
Sen-Yung Hsieh (Chang Gung Memorial Hospital, TAIWAN), Ying-Chin Chen<br />
Metastasis-Associated C4.4a, A Gpi-Anchored Protein Cleaved By Adam10 And<br />
Adam17<br />
Cary Esselens, Jordi Malapeira, Nuria Colome, Joaquin Arribas, Francesc Canals,<br />
Wolfgang Jabs (Bruker Daltonik GmbH, GERMANY), Detlev Suckau, Carsten<br />
Baessmann<br />
P-TUE-074<br />
P-TUE-075<br />
P-TUE-076<br />
P-TUE-077<br />
Discovery Of Pra1-Associated Dysregulated Proteins By Itraq And<br />
Multidimensional Lc-Ms/Ms<br />
Hao-Ping Liu (Institute of Basic Medical Science, Chang Gung University, TAIWAN)<br />
Exploration Of The Cathepsin D Protein Complexes In Senescent Pathways<br />
Xiaomin Lou (Beijing Genomics Institute, Chinese Academy of Sciences / Beijing<br />
Proteomics Institute, CHINA), Ju Zhang, Maomao Sun, Siqi Liu, Ningzhi Xu<br />
Down-Regulation Of Ptk6 In Breast Cancer Cell Lines For Identification Of Novel<br />
Therapy Targets<br />
Natalie Ludyga (Helmholtz Zentrum München - German Research Center for<br />
Environmental Health, GERMANY), Manuela Ram, Natasa Anastasov, Ulrike Reich,<br />
Heinz Höfler, Michaela Aubele<br />
Identification Of Proteins Targeted By Apc/C-Cdh1 During Mitosis Exit By Silac<br />
Jose L. Luque-Garcia (Protein Technology Unit. Spanish National Cancer Research<br />
Center (Cnio), SPAIN), Eusebio Manchado, Marcos Malumbres, Ignacio Casal<br />
102 103
P-TUE-078<br />
P-TUE-079<br />
P-TUE-080<br />
P-TUE-081<br />
P-TUE-082<br />
P-TUE-083<br />
P-TUE-084<br />
P-TUE-085<br />
P-TUE-086<br />
P-TUE-087<br />
P-TUE-088<br />
P-TUE-089<br />
Proteome And Phosphoproteome Dynamics In Human Cells Upon Inhibition Of<br />
Hsp90<br />
Boris Macek (Mpi for Biochemistry, Dept. of ProteoMics and Signal Transduction,<br />
GERMANY), Martin Vabulas, Chanchal Kumar, Florian Gnad, Ulrich Hartl, Matthias<br />
Mann<br />
Proteomic Analysis Of The Interacting Partners Of The Spindle Checkpoint<br />
Protein Bub3<br />
Alessio Maiolica (European Institute of Oncology Ieo, ITALY), Silvia Monzani, Paolo<br />
Soffientini, Andrea Musacchio<br />
Far Upstream Element Binding Protein-1, A C-Myc Transcription Factor, Is<br />
Cleaved By Caspases During Apoptosis<br />
Jang Mi (KOREA)<br />
Proteomic Analysis Of TransforminG Growth Factor Beta Signaling In Colon<br />
Cancer Cells<br />
Naveid Ali, Karlie Nielson, Mark Molloy (Macquarie University, AUSTRALIA)<br />
Withdrawn<br />
Indoor Air Exposure Of Volatile Organic Compounds On Human Alveolar Cells<br />
Nora Mörbt (Department of Proteomics, Helmholtz-Centre for Environmental<br />
Research, GERMANY), Frank Schmidt, Ralph Feltens, Carmen Röder-Stolinski,<br />
Gundula Fischäder, Irina Lehmann, Martin Von Bergen<br />
Complex Formation Between S100a11 And Rad54b At Dna Damage Sites<br />
Ulrike Murzik (Institute of Human Genetics and Anthropology, Medical Faculty,<br />
Friedrich-Schiller-University, GERMANY), Peter Hemmerich, Juliane Jung, Ferdinand<br />
von Eggeling, Christian Melle<br />
Proteomics Of Pcna: Cell Transformation Is Accompanied By Up-Regulation Of<br />
Pcna Without Post-Translational Modifications<br />
Stanislav Naryzhny (Hrsrh, CANADA), Hoyun Lee<br />
Label-Free Proteome Profiling Of Archival Childhood Brainstem Tumors<br />
Javad Nazarian (Children’s National Medical Center, UNITED STATES), Brian Halligan,<br />
Mariarita Santi, Tobey Macdonald, Yetrib Hathout<br />
Novel Functional Approach Combining Reverse Phase Protein Micorarrays<br />
(Rpma) And 3d Ex-Vivo Tissue Cultures: Expression Analysis Of Apoptosis-<br />
Related Proteins In Human Colon Cancer And Response To Chemotherapeutic<br />
Treatment<br />
Michael Pawlak (Nmi Natural and Medical Sciences Institute, GERMANY), Gerhard<br />
G. Thallinger, Markus F. Templin, Markus Borner<br />
Secreted Proteins Of Malignant Breast Cells Coordinate Angiogenesis Through<br />
Ecm Degradation<br />
Xiquan Liang, Jarkko Huuskonen, Mahbod Hajivandi, Paul Predki, Marshall Pope<br />
(Invitrogen, UNITED STATES)<br />
Protein Expression Analysis By 2d-Dige Of Different Areas Of Gbm From<br />
Patient Biopsies<br />
Roberto Raggiaschi (Siena Biotech S.P.A., ITALY), Silvia Matteoni, Annunziato<br />
Mangiola, Letizia Magnoni, Stefano Gotta, Andreas Kremer, Marco Rossi, Silvia<br />
Valensin, Annette Bakker<br />
P-TUE-090<br />
P-TUE-091<br />
P-TUE-092<br />
P-TUE-093<br />
P-TUE-094<br />
P-TUE-095<br />
P-TUE-096<br />
P-TUE-097<br />
P-TUE-098<br />
P-TUE-099<br />
P-TUE-100<br />
Search For Markers Predicting The Cisplatin Chemosensitivity In Large-Cell<br />
Neuroendocrine Carcinoma<br />
Yuichi Sato (Department of Molecular Diagnostics, Kitasato University School of Allied<br />
Healh Scinences / Department f Molecular Diagnostics, Kitasato University Graduate<br />
School of Medical Siences / Center for Disease Proteomics, Kitasato University<br />
School of Science, JAPAN), Taihei Kageyama, Ryo Nagashio, Toshihide Tatsumoto,<br />
Mihoko Ohnishi, Yoshio Kodera, Tadakazu Maeda, Shi-Xu Jiang, Isao Okayasu<br />
Macrophage-Differentiating Factors Of Cancer Cell Lines Studied By Secretome<br />
Profiling<br />
Silvia Schiarea (Istituto di Ricerche Farmacologiche Mario Negri, ITALY), Paola<br />
Allavena, Graziella Solinas, Roberto Fanelli, Chiara Chiabrando<br />
Spink3 Is An Indicator Of Erbeta Negative, Poorly Differentiated Prostatic<br />
Epithelium<br />
Thomas Schwend (Karolinska Institute, SWEDEN), Otabek Imamov, Thomas Ruppert,<br />
Linda Waage, Ulf Bergerheim, Jan-Ãke Gustafsson<br />
From Proteomics To Molecular Targets For Elimination Of Apoptosis-Resistant<br />
Leukemic Cells<br />
Tereza Simonova (Department Of Pathophysiology, First Faculty Of Medicine, Charles<br />
University, CZECH REPUBLIC), Ondrej Toman, Petr Halada, Pavel Klener, Jan Zivny,<br />
Jiri Petrak<br />
Identification Of Holliday Junction (Hj) Processing Enzymes In Human Cells<br />
J Mark Skehel (Cancer Research Uk, UNITED KINGDOM), Stephen Ip, Helen Flynn,<br />
Simon Swindell, Mark Pitman, Stephen West<br />
Proteomics Of Breast Cancer: Systemic Analysis Of Various Datasets To Identify<br />
Markers And Drug Targets<br />
Serhiy Souchelnytskyi (Karolinska Biomics Center, SWEDEN)<br />
Quantitative Proteome And Phosphoproteome Analysis Of Fasl/Trail-Induced<br />
Apoptosis<br />
Gabriele Stoehr (Department of Proteomics and Signal Transduction, Max Planck<br />
Institute for Biochemistry, GERMANY), Chunaram Choudhary, Boris Macek,<br />
Matthias Mann<br />
Identification Of P53 Interacting Proteins In Nasopharyngeal Carcinoma Cells By<br />
Proteomics Analysis<br />
Yi Sun (Key Laboratory of Cancer Proteomics of Chinese Ministry of Health,<br />
Xiangya Hospital / Cancer Research Institute, Xiangya School of Medicine / Human<br />
Reproductive and Stem Cell Engineering Institute, CHINA), Zhi-Qiang Xiao, Zhu-Chu<br />
Chen, Mao-Yu Li<br />
Tissue Transglutaminase 2 Could Be A Novel Candidate Of Hepatocellular Carcinoma<br />
Yilin Sun (State Key Labotatory of Molecular Oncology, Cancer Institute & Hospital,<br />
Chinese Academy of Medical Sciences, CHINA), Wei Mi, Jianqiang Cai, Wantao Ying,<br />
Fang Liu, Lei Li, Wei Jia, Lanping Zhou, Xinyu Bi, Haizhen Lu<br />
Escape Mechanisms In Metronomic Cyclophosphamide Therapy In Vivo<br />
Lilja Thoenes (Lmu Munich, GERMANY), Michael Guenther, Manfred Ogris, Georg J.<br />
Arnold, Ernst Wagner<br />
Silencing Bcl-2 In Mantle Cell Lymphoma<br />
Catherine Tucker (Department of Advanced Therapeutics / DepartMent of Pathology<br />
and Laboratory Medicine, CANADA), Anita Kapanen, Ghania Chikh, Brad Hoffman,<br />
Alastair Kyle, Ian Wilson, Dana Masin, Randy Gascoyne, Marcel Bally, Richard Klasa<br />
104 105
P-TUE-101<br />
P-TUE-102<br />
Characterisation Of Signal Transduction Complexes Associated With The C-Kit<br />
Receptor<br />
Jurjen van Bolhuis (Erasmus University Mc, THE NETHERLANDS)<br />
Proteomic Profiling Of Glioblastoma Cells Following mir-21 Knockdown<br />
Matthew Willetts (Applied Biosystems, UNITED STATES), Marjorie Minkoff, Thales<br />
Papagiannakopoulos, Kenneth Kosik, Phil Ross, Darryl Pappin<br />
Chemical Proteomics<br />
P-TUE-111<br />
Selectivity In Enrichment Of Pka And Their Interactors Using Modified Affinity<br />
Resins And Chemical Proteomics<br />
Thin Thin Aye (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />
University; Department of Medical Physiology, University Medical Centre, THE<br />
NETHERLANDS)<br />
P-TUE-103<br />
Ca11, An Autocrine Protein In Gastric Epithelium, Plays A Role In Regulation Of<br />
Cell Cycle<br />
Rui Xing (Beijing Genomics Institute, Cas, CHINA), Jun Zhang, Bin Kang, Siqi Liu,<br />
Youyong Lu<br />
P-TUE-112<br />
A Chemical Proteomics Approach For Assessing Target Selectivity Of Kinase<br />
Inhibitors<br />
Marcus Bantscheff (Cellzome Ag, GERMANY), Dirk Eberhard, Friedrich Reinhard,<br />
Carsten Hopf, Ulrich Kruse, Bernhard Kuster, Gerard Drewes<br />
P-TUE-104<br />
P-TUE-105<br />
Phosphorylation Of Eef1a1 By Tgf-Beta Receptor<br />
Ihor Yakymovych (Karolinska Biomics Center, Department of Oncology-Pathology,<br />
Karolinska University Hospital, SWEDEN), Mariya Yakymovych, Serhiy Souchelnytskyi<br />
Cross-Link Of Proteome With Transcriptome For Metastasis Hcc<br />
Pengyuan Yang (Institutes for Biomedical Sciences and Research Institute for Liver<br />
Cancer, Fudan Uni Shanghai, CHINA)<br />
P-TUE-113<br />
P-TUE-114<br />
Fast Enzymatic Protein Digestion: Microwave Versus Ultrasonication<br />
Jose-Luis Capelo-Martínez (New University of Lisbon, Portugal)<br />
Proteomics Of Stressed Chondrocytes To UndersTand Mechanisms Of Skeletal<br />
Dysplasia<br />
Wai Ling Chan (The University of Hong Kong, CHINA), Danny Chan, Stephen Lee, Kse<br />
Cheah, Julian A. Tanner<br />
P-TUE-106<br />
P-TUE-107<br />
Proteomics Analysis Of Anti-Cancer Activity Of Luteolin In Human Hepatoma<br />
Huh-7 Cells<br />
Dong-Ryeol Yoo (Gachon University of Medicine and Science, KOREA), Young-Keul<br />
Jeon, Yun-Ho Jang, Dong-Jin Yim, Ju-Yeon Kim, Won Jeon, Chae-Jun Lim, Myeong-Jin<br />
Nam<br />
Proteome Profiling Of Human Breast Cancer (Case Studies)<br />
Olena Zakharchenko (Karolinska BIomics Center, SWEDEN)<br />
P-TUE-115<br />
P-TUE-116<br />
Fluorescein As A Versatile Tag For Enhanced Selectivity In Analyzing Cysteine-<br />
Containing Proteins/Peptides Using Mass Spectrometry<br />
Shu-Hui Chen, Jue-Liang Hsu, Fong-Sian Lin, Pai-Chiao Cheng (Department of<br />
Chemistry, National Cheng Kung University, TAIWAN)<br />
Modified Au Nanoparticles For Resolving Protein Complexes Related To Estrogen<br />
Action<br />
Pai-Chiao Cheng (National Cheng Kung University, TAIWAN)<br />
P-TUE-108<br />
P-TUE-109<br />
P-TUE-110<br />
Mapping The Melanoma Phosphoproteome By High Resolution Mass<br />
Spectrometry<br />
Sara Zanivan (Max-Planck Institute for Biochemistry, Dept of Proteomics and Signal<br />
Transduction, GERMANY), Sara Wickström, Tami Geiger, Juergen Cox, Florian Gnad,<br />
Boris Macek, Reinhard Fässler, Matthias Mann<br />
Exploring The Functions Of Bag2 Complexes In Cell Senescence<br />
Ju Zhang (Beijing Genomics Institute, Chinese Academy of Science / Beijing<br />
Proteomics Institute, CHINA), Xiaomin Lou, ShanGbin Yang, Siqi Liu, Ningzhi Xu<br />
The Interaction Of Mawbp/Mawd Is Likely Involved In Tgf-Beta Signaling<br />
Pathway<br />
Jun Zhang (Beijing Genomics Institute, Chinese Academy of Sciences / Beijing<br />
Proteomics Institute, CHINA), Bin Kang, Rui Xing, Ningzhi Xu, Siqi Liu, Youyong Lu<br />
P-TUE-117<br />
P-TUE-118<br />
P-TUE-1<strong>19</strong><br />
P-TUE-120<br />
Withdrawn<br />
Assessing Dynamic Change Of Protein S-Nitrosylation By Label-Free<br />
Quantitative Proteomics<br />
Hsiao-Chiao Chou (Department of Chemistry, National Taiwan University, TAIWAN),<br />
Yi-Ju Chen, Wei-Chi Ku, Yu-Ju Chen<br />
Using Chemical Proteomics And Peptide Disrupters Technology To Evaluate Ri<br />
And Rii Specific Akaps<br />
Alessandro Cuomo (Ceinge Biotecnologie Avanzate, °S.E.M.M. -European School of<br />
Molecular Medicine, ITALY)<br />
Quantitative Chemical Proteomics: A Tool For Investigating (Off-) Target Binding<br />
Poupak Dadvar (Utrecht Institute for Pharmaceutical Sciences, THE<br />
NETHERLANDS), Arjen Scholten, Shabaz Mohammed, Bas Breukelen, Klaus Rumpel,<br />
Albert Heck<br />
P-TUE-121<br />
Functionality Directed Reduction Of Proteome Complexity<br />
Christian Dalhoff (Caprotec Bioanalytics GmbH, GERMANY), Peter Poot, Michael<br />
Hüben, Thomas Lenz, Christian Jurinke, Elmar Weinhold, Hubert Köster<br />
P-TUE-122<br />
Chemical Proteomics Strategy Reports On Proteasome Activity In Living Cells<br />
Bogdan (Bobby) Florea (Dept of Bio-Organic Chemistry, Leiden Institute of<br />
Chemistry, Leiden University, THE NETHERLANDS)<br />
P-TUE-123<br />
The Two Phase Partitioning System For Purification Of C. Glutamicum Membrane<br />
Proteins<br />
Benjamin Fränzel, Dirk Wolters (Analytical Chemistry, Ruhr University Bochum,<br />
GERMANY)<br />
106 107
P-TUE-124<br />
Functionalized Succinylhydroxamate Peptide Inhibitors For Activity-Based<br />
Enrichment Of Mmps/Adams<br />
Paul Geurink (Leiden University, THE NETHERLANDS), Theo Klein, Gijs van der Marel,<br />
Rainer Bischoff, Herman Overkleeft<br />
Computational Approaches To Mine Proteomic Data<br />
P-TUE-136<br />
Systems Biology For Compound And Protein Classification, And Interaction Mapping<br />
Ken Aoshima (Eisai Co., Ltd., JAPAN), Yoshiya Oda, Yuji Miura, Masumi Takahashi<br />
P-TUE-125<br />
P-TUE-126<br />
P-TUE-127<br />
P-TUE-128<br />
P-TUE-129<br />
Withdrawn<br />
Affinity Pull-Down Of Metalloproteases From Arabidopsis Thaliana<br />
Janina Lenger (Bioorganic Chemistry, Department of Chemistry, Bielefeld University,<br />
GERMANY), Jens Conradi, Hannes Patrik Plattner, Karl-Josef Dietz, Norbert Sewald<br />
Detection Of Galectin-3 By The Use Of Chemical Probes<br />
Monique van Scherpenzeel (Uu, THE NETHERLANDS), Rob M.J. Liskamp, Roland J.<br />
Pieters<br />
Ultrasonic Assisted Enzymatic Protein Digestion Kinetic Studies<br />
Carlos Lodeiro (Requimte- Chemistry Department, Faculty of Science and<br />
Technology, University Nova of Lisbon, Monte de Caparica, Portugal), Diana V. Vieira,<br />
Hugo M. Santos, Issa Isaac, José Luis Capelo<br />
Protein Kinase C Microarray Profiling To Design Isozyme Selective Inhibitors<br />
Alex J. Poot (Utrecht University, THE NETHERLANDS), Jeroen Ameijde, Rob<br />
Ruijtenbeek, Riet Hilhorst, Monique Slijper, Dirk T.S. Rijkers, Rob M.J. Liskamp<br />
P-TUE-137<br />
P-TUE-138<br />
P-TUE-139<br />
P-TUE-140<br />
Postman, A New Tool For Comparative Lc-Ms In Ptm Detection<br />
Magnus Arntzen (Probe Proteomic Unit, Department of Biomedicine, University of<br />
Bergen, NORWAY), Christoffer Osland, Christopher Raa, Maria Ekman, Burkhard<br />
Fleckenstein, Aurelia Lewis, Clive Dsantos<br />
Of Planets And Portability: A Common Api For Desktop Proteomics Data Analysis<br />
Manor Askenazi (Dana-Farber Cancer Institute, UNITED STATES), Jignesh Parikh,<br />
Tanya Cashorali, Scott Ficarro, Yi Zhang, Nathaniel Blank, Jarrod Marto<br />
Close Correlations Between Transcript And Proteome Expression Of Gene-<br />
Protein Pairs Across Heart- And Skeletal Muscle<br />
Emøke Bendixen (University of Århus, DENMARK), Frank Panitz, Henrik Hornshøj,<br />
Lene Conley, Pernille Andersen, Jakob Hedegaard, Christian Bendixen<br />
Increase Identification Rate By Combining On-The-Fly Spectral Library And<br />
Sequence Searches<br />
Erik Ahrne, Markus Müller, Pierre-Alain Binz, Alexandre Masselot, Frederique Lisacek<br />
(Swiss Institute of Bioinformatics, Proteome Informatics Group, SWITZERLAND)<br />
P-TUE-130<br />
P-TUE-131<br />
Proteomic Analysis Of Macrophages Stimulated By Lipopolysaccharide And<br />
Treated With Celecoxib As Selective Cox-2 Inhibitor<br />
Mona Salimi (Research & Development Center, Pasteur Institute of Iran, Karaj,<br />
IRAN), Faegheh Rezaee, Soudabeh Akbarzadeh, Mohammad Hossein Ghahremani,<br />
Behrouz Vaziri<br />
Desalting Free Ultrasonic-BaSed Method For Protein Identification By Pmf<br />
Hugo Miguel Santos (Requimte - Chemistry Department Fct-Unl, PORTUGAL),<br />
Cristiano Mota, Isabel Moura, Carlos Lodeiro, Issa Isaac, José-Luis Capelo<br />
P-TUE-141<br />
P-TUE-142<br />
On The Stability Of Peptide Identifications When Looking At Variations In<br />
Ms/Ms Spectra<br />
Markus Müller, Pierre-Alain Binz, David Bouyssié, Frederique Lisacek, Olivier Philippe<br />
(Geneva Bioinformatics (Genebio), SWITZERLAND)<br />
Classification Using A 1d Representation Of Lc-Ms Data<br />
Tom Bloemberg (Analytical Chemistry - Institute for Molecules and Materials -<br />
Radboud University Nijmegen, THE NETHERLANDS), Jolein Gloerich, Hans Wessels,<br />
Wendy Pluk, Ron Wehrens, Lambert van den Heuvel, Lutgarde Buydens<br />
P-TUE-132<br />
Paired Stable Isotope Metabolic Tracers: A Novel Approach For Discovery Of<br />
Drug Metabolites<br />
Nicolas A.S. Stewart (University of Pittsburgh, UNITED STATES), Jennifer N.<br />
Sutton, Brian L. Hood, Raman Venkataramanan, Michael Athanas, Robert A. Branch,<br />
Thomas P. Conrads<br />
P-TUE-143<br />
Icplquant - A New Software Tool For Isotope-Labelling Based Proteomics And<br />
Biomarker Discovery<br />
Achim Brunner (Max-Planck Institute of Biochemistry, Martinsried, GERMANY),<br />
Eva-Maria Keidel, Monica Zobawa, Silke Martin, Michael Kersten, Josef Kellermann,<br />
Friedrich Lottspeich<br />
P-TUE-133<br />
P-TUE-134<br />
P-TUE-135<br />
Probing Proteasome Regulation<br />
Wouter van der Linden (Biosyn Leiden University, THE NETHERLANDS), Martijn<br />
Verdoes, Bobby Florea, Gijsbert van der Marel, Herman Overkleeft<br />
Chemical Tools To Probe The Proteasome<br />
Martijn Verdoes (Bioorganic Synthesis, Leiden Institute of Chemistry, THE<br />
NETHERLANDS), Bogdan Florea, Ulrik Hillaert, Wouter van der Linden, Lianne<br />
Willems, Myra Sae-Heng, Gijsbert van der Marel, Herman Overkleeft<br />
The Synthesis And Biological Evaluation Of Peptide N-Glycanase Inhibitors<br />
Martin D. Witte (Bioorganic Synthesis, Leiden Institute of Chemistry, THE<br />
NETHERLANDS), Bogdan I. Florea, Gijsbert van der Marel, Herman S. Overkleeft<br />
P-TUE-144<br />
P-TUE-145<br />
P-TUE-146<br />
P-TUE-147<br />
Withdrawn<br />
The Gene Ontology Annotation (Goa) Project At The Ebi<br />
Emily Dimmer (European Bioinformatics Institute, UNITED KINGDOM), Rachael<br />
Huntley, Daniel Barrell, David Binns, Claire O’Donovan, Rolf Apweiler<br />
Identification And Quantification Of Endogenous Peptides In A Model Of<br />
Parkinson’s Disease<br />
Maria Falth (Uppsala University, SWEDEN), Anna Nilsson, Kim Kultima, David Fenyö,<br />
Per Svenningsson, Per Andren<br />
On The Peptide Fragment Mass Information Required To Identify Peptides<br />
David Fenyo (The Rockefeller University, UNITED STATES), Elena Ossipova, Jan Eriksson<br />
P-TUE-148<br />
Keynode AnaylysiS ¡V Method To Identify Potential Biomarkers For Dominant<br />
Signaling Pathways<br />
Yi Man Eva Fung (Division of Molecular Biometry, Institute for Cell and Molecular Biology,<br />
Uppsala University, SWEDEN), Roman A. Zubarev, Peter Bergsten, Hanna Nyblom<br />
108 109
P-TUE-149<br />
Machine Learning-Based Membrane Protein Identification<br />
Tejas Gandhi (Membrane Enzymology Group / Groningen Bioinformatics Center,<br />
University of Groningen, THE NETHERLANDS), Bert Poolman, Hjalmar Permentier,<br />
Rainer Brietling<br />
P-TUE-162<br />
Probability Assignment And Protein Inference For Accurate Mass And Time<br />
Analysis<br />
Damon May (Fred Hutchinson Cancer Research Center, UNITED STATES), Yan Liu,<br />
Wendy Law, Martin Mcintosh<br />
P-TUE-150<br />
P-TUE-151<br />
P-TUE-152<br />
P-TUE-153<br />
Withdrawn<br />
Peptizer: A Rule-Based Bioinformatics Tool To Select Suspicious Peptide<br />
Identifications<br />
Kenny Helsens (Department of Medical Protein Research/ Department of<br />
Biochemistry, Ghent University, BELGIUM), Evy Timmerman, Joël Vandekerckhove,<br />
Kris Gevaert, Lennart Martens<br />
A Machine Learning Approach For Ranking Of Proteotypic Peptides For Ms<br />
Carsten Henneges (Wilhelm-Schickard-Institute / Computerarchitecture,<br />
GERMANY), Georg Hinselmann, Johannes Madlung, Stephan Jung, Tobias<br />
Lamkemeyer, Alfred Nordheim, Andreas Zell<br />
Withdrawn<br />
P-TUE-163<br />
P-TUE-164<br />
P-TUE-165<br />
New Developments For Open-Source Shotgun Proteomics Analysis With The<br />
Trans-Proteomic Pipeline<br />
Luis Mendoza (Institute for Systems Biology, UNITED STATES), Joshua Tasman,<br />
David Shteynberg, James Eddes, Brian Pratt, Eric Deutsch, Chee-Hong Wong,<br />
Henry Lam, Jimmy Eng, Ruedi Aebersold<br />
Identifying Unexpected Modifications Using Accurate Mass Ms And A New<br />
Search Algorithm<br />
Christine A. Miller (Agilent Technologies, UNITED STATES), David M. Horn, Joseph C. Roark<br />
Analysis Of Peak Intensity Correlations To Improve Diagnostic Accuracy And Maximize<br />
Biological Meaning Of Mass-Spectral Diagnostics Of Ovarian And Prostate Cancer<br />
Sergey Moshkovskiy (Institute of Biomedical Chemistry Rams, RUSSIAN FEDERATION),<br />
M Vlasova, M Pyatnitsky, I ToropygIn, A Archakov<br />
P-TUE-154<br />
P-TUE-155<br />
P-TUE-156<br />
P-TUE-157<br />
P-TUE-158<br />
P-TUE-159<br />
P-TUE-160<br />
P-TUE-161<br />
Proteomedigger: A Versatile Disease Proteome Database And Analysis Platform<br />
For The Discovery Of Plasma-Localized Cancer Biomarkers.<br />
Seul-Ki Jeong (Department of Biochemistry, Yonsei Proteome Research Center and<br />
Biomedical Proteome Research Center, KOREA), Min-Seok Kwon, Eun-Young Lee,<br />
Sang Yun Cho, Hoguen Kim, Gilbert S. Omenn, Ruedi Aebersold, Young-Ki Paik<br />
Calculation Of Unique Peptide Sequences For Unambiguous Identification Of<br />
Highly Homologous Proteins<br />
Michael Kohl (Medizinisches Proteom Center, GERMANY), Gorden Redlich, Martin<br />
Eisenacher, Anke Schnabel, Katrin Marcus, Helmut E. Meyer, Christian Stephan<br />
Consensus Predictors For Peptide Detectability<br />
King Wai Lau (Faculty of Life Sciences, University of Manchester, UNITED<br />
KINGDOM), Claire Eyers, David Wedge, Simon Gaskell, Simon J Hubbard<br />
Pnmerge: A Novel Cytoscape Plugin To Merge The Biological Pathway And<br />
Protein Networks<br />
Hanchang Sun, Dong Li (The State Key Laboratory of Proteomics, Beijing Proteome<br />
Research Center, Beijing Institute of Radiation Medicine, CHINA), Jian Wang,<br />
Hongwei Xie, Yunping Zhu, Fuchu He<br />
Comparative Analysis Of Various Parsimony Methods And Its Influence Factors<br />
For Protein Inference In Shotgun Proteomics<br />
Ning Li (State Key Laboratory of Proteomics, Beijing Proteome Research Center,<br />
Beijing Institute of Radiation Medicine, CHINA), Songfeng Wu, Yunping Zhu, Fuchu He<br />
A Missing Piece In Proteomics Identification Task: The Protein Family Tree<br />
Michal Linial (The Hebrew University of Jerusalem, Israel), Menachem Fromer,<br />
Solange Karsenty, Yaniv Loewenstein<br />
X!Tandem Powered By Cell Be Processor Runs 10-Times Faster Than The Same<br />
On A Pc<br />
Yaroslav Lyurvinskiy (Institut for Analytical Instrumentation, RUSSIAN<br />
FEDERATION), Sergej Fironov, Nikolay Krasnov<br />
Conservation And Stoichiometry Of The Human Mitotic Spindle Phosphoproteome<br />
Rainer Malik (Max Planck Institute for Biochemistry, Department of Cell Biology,<br />
GERMANY), Erich A. Nigg, Roman Körner<br />
P-TUE-166<br />
P-TUE-167<br />
P-TUE-168<br />
P-TUE-169<br />
P-TUE-170<br />
P-TUE-171<br />
P-TUE-172<br />
P-TUE-173<br />
P-TUE-174<br />
Assessing Significance Of Protein-Protein Interactions Using Spectral Counts<br />
Hyungwon Choi, Ashton Breitkreutz, Brett G. Larsen, Zhaohui S. Qin, Anne-Claude<br />
Gingras, Mike Tyers, Alexey I. Nesvizhskii (University of Michigan, Department of<br />
Pathology, UNITED STATES)<br />
Software Tools For The Analysis Of Quantitative Proteomics Data<br />
Lars Nilse (Manchester University, UNITED KINGDOM)<br />
Comparative Proteomic Phenotyping To Assess Preservation Of Cell Functions<br />
Cuiping Pan (Max-Planck Institute for Biochemistry, GERMANY), Chanchal Kumar,<br />
Sebastian Bohl, Ursula Klingmueller, Matthias Mann<br />
Identification Of Low Quality Peptide Ms/Ms Spectra Using Dominant<br />
Fragmentation Patterns<br />
Hjalmar Permentier (University of Groningen, THE NETHERLANDS), Elena Wiederhold,<br />
Bert Poolman<br />
The Same Proteins Again? A Hit Parade Of Differentially Expressed Proteins<br />
Repeatedly Identified By 2-De<br />
Jiri Petrak (Institute of Hematology and Blood Transfusion / Department of<br />
Pathophysiology, First Faculty of Medicine, Charles University, CZECH REPUBLIC),<br />
Robert Ivanek, Ondrej Toman, Daniel Vyoral, Jan Zivny, Christopher Vulpe<br />
Intensity-Based Differential Analysis Of Complex Protein Mixtures Using Two-<br />
Dimensional (2dlc and Gelc) Datasets Coupled To Ms/Ms<br />
Thang Pham (Vu University Medical Center, THE NETHERLANDS), Sander Piersma,<br />
Connie Jimenez<br />
Automated Meta-Analysis Confirms The Hit-Parade Of Repeatedly Identified Proteins<br />
Elena Ponomarenko (Institute of Biomedical Chemistry Rams, RUSSIAN FEDERATION),<br />
A Lisitsa, J Petrak, S Moshkovskiy, A Archakov<br />
Evaluation Of Efficiency Of Cross-Species Comparisons<br />
Derek Potter (Proxeon A/S, DENMARK), Hans Jespersen, Alexandre Podtelejnikov,<br />
Morten Bern<br />
Analysis Workflows To Mine Mass Spectrometry Data<br />
Andreas Quandt (Swiss Institute of Bioinformatics, SWITZERLAND), Patricia<br />
Hernandez, Alexandre Masselot, Celine Hernandez, Sergio Maffioletti, Cesare<br />
Pautasso, Ron D. Appel, Frederique Lisacek<br />
110 111
P-TUE-175 Nist Reference Libraries Of Peptide Fragmentation Spectra: 2008<br />
Paul Rudnick (Nist, UNITED STATES), Niksa Blonder, Yuri Mirokhin, Lewis Geer,<br />
Dmitrii Tchekhovskoi, Lisa Kilpatrick, Jeri Roth, Qian Dong, Stephen Stein<br />
P-TUE-176<br />
P-TUE-177<br />
P-TUE-178<br />
P-TUE-179<br />
P-TUE-180<br />
P-TUE-181<br />
P-TUE-182<br />
P-TUE-183<br />
P-TUE-184<br />
P-TUE-185<br />
P-TUE-186<br />
P-TUE-187<br />
P-TUE-188<br />
Software Supported Process Optimization For Magnetic Beads Purification Of<br />
Glycoproteins<br />
Ulrike Schweiger-Hufnagel (Bruker Daltonik GmbH, GERMANY), Peter Hufnagel,<br />
Stefan Weise, Arnd Asperger, Katrin Sparbier, Irina Kessler, Markus Kostrzewa,<br />
Detlev Suckau<br />
WIelding The Double Edged Sword Of Multiple Ms/Ms Searching Engines<br />
Brian Searle (Proteome Software Inc., UNITED STATES), Mark Turner<br />
Protein Identification With Linear Programming<br />
Oliver Serang (University of Washington, UNITED STATES)<br />
Extensive Peptide Identification Via Sequence Temperature Values And Feature<br />
Probabilities<br />
Sean L. Seymour (Applied Biosystems|Mds Analytical Technologies, UNITED STATES),<br />
Ignat V. Shilov, Alpesh A. Patel, Wilfred H. Tang, Alex Loboda, Christie L. Hunter,<br />
Lydia M. Nuwaysir, Daniel A. Schaeffer<br />
Protein Methylation Site Prediction Using Profile-Based Bayesian Kernel Feature<br />
Extraction<br />
Jianlin Shao (Department of Biology, The Chinese University of Hong Kong, CHINA),<br />
Saiming Ngai<br />
Iprophet: Improved Validation Of Peptide Identification In Shotgun Proteomics.<br />
David Shteynberg (Institute for Systems Biology, UNITED STATES), Eric Deutsch,<br />
Henry Lam, Ruedi Aebersold, Alexey Nesvizhskii<br />
Rapid Proteome Profiling And Genome Annotation Using Positional Signature Peptides<br />
Jennifer Siepen (University of Manchester, UNITED KINGDOM), Lucy Mcdonald,<br />
James Wright, Robert Beynon, Simon Hubbard<br />
N-Dimensional Grouping As A Tool For Mining Proteomic Expression Profiling Data<br />
Stephen Tate (Mds Analytical Technologies, CANADA), Devando Pinto, Ron Bonner,<br />
Lyle Burton, Gordana Ivosev<br />
Proteomics Pipelining And Profiling Of Mass Spectrometry Data (P²M)<br />
Felix Tschoerner (Experimental Ophthalmology, Department of Ophthalmology, University<br />
of Mainz, GERMANY), Phllip Kroll, Marcel Blindert, Nils Boehm, Norbert Pfeiffer, Franz Grus<br />
Predicting Protein-Protein Interaction Motifs Based On Proteomic Interaction Data<br />
Aalt-Jan van Dijk (Plant Research International, Wageningen Ur, THE NETHERLANDS),<br />
Cajo ter Braak, Richard Immink, Gerco Angenent, Roeland van Ham<br />
Comparative Functional Analysis Of The Caenorhabditis Elegans And Drosophila<br />
Melanogaster Proteomes<br />
Manuel Weiss (University of Zurich, SWITZERLAND)<br />
Spectral Profile Libraries For Cross Species Proteomics<br />
James Wright (Veterinary Pre-Clinical Sciences, The University of Liverpool / Faculty<br />
of Life Sciences, The University of Manchester, UNITED KINGDOM), Simon Hubbard,<br />
Robert Beynon<br />
ProConf: A New Method To Estimate The False Positive Ratio Employing<br />
Hypergeometric Distribution Model<br />
Songfeng Wu (Beijing Proteome Research Center, CHINA), Ning Li, Jie Ma, Yunping<br />
Zhu, Fuchu He<br />
P-TUE-189<br />
P-TUE-<strong>19</strong>0<br />
P-TUE-<strong>19</strong>1<br />
P-TUE-<strong>19</strong>2<br />
P-TUE-<strong>19</strong>3<br />
Connecting Nci Proteomics Repository To The Cancer Biomedical Informatics<br />
Grid (Cabig)<br />
Liming Yang (National Cancer Institute, UNITED STATES), Denny Chan, Carl Blake,<br />
Carl Schaefer<br />
High Confident Protein Id Of Etd And Ecd Spectra With A New Mass List<br />
Preprocessor<br />
Martin Zeller (Thermo Fisher Scientific, GERMANY), Bernard Delanghe, Torsten Ueckert<br />
An Innovative Algorithm For Sequence Motif Search<br />
Jianjun Zhang (Genentech Inc., UNITED STATES), Colin Watanabe<br />
Msaq: A New Software For Quantitative Proteomic Analysis With Stable<br />
Isotope-Coded Labeling<br />
Jiyang Zhang, Xin Liu, Hongwei Xie, Yunping Zhu (State Key Laboratory of<br />
Proteomics / Beijing Proteome Research Center / Beijing Institute of Radiation<br />
Medicine, CHINA), Xiaohong Qian, Fuchu He<br />
Prelocabc-- A Novel Predictor For Proteins’ Subcellular Localization By A<br />
Bayesian Classifier<br />
Yanqiong Zhang, Tao Li, Chunyuan Yang, Yunping Zhu (State Key Laboratory of<br />
Proteomics / Beijing Proteome Research Center / Beijing Institute of Radiation<br />
Medicine, CHINA), Fuchu He<br />
Glycoproteomics<br />
P-TUE-<strong>19</strong>4<br />
P-TUE-<strong>19</strong>5<br />
P-TUE-<strong>19</strong>6<br />
P-TUE-<strong>19</strong>7<br />
P-TUE-<strong>19</strong>8<br />
P-TUE-<strong>19</strong>9<br />
P-TUE-200<br />
P-TUE-201<br />
The Er N-Glycoproteome Research Of C57bl/6j Mouse<br />
Yun Cai (State Key Laboratory of Proteomics, Beijing Proteome Research Center.<br />
Beijing Institute of Radiation Medicine, CHINA)<br />
Proteomics Approach To Identify Serum Glycoproteins As Biomarkers Of Human<br />
Lung Adenocarcinoma<br />
Chu-Ling Wen (Graguate Institute of Biochemistry and Molecularbiology, Collage of<br />
Medicine, National Taiwan University, TAIWAN), Lu-Ping Chow<br />
Characterization Of Ptms And Their Effect On Enzyme Activity And Stability<br />
Maja Christiansen (Novozymes A/S University of Southern Denmark, DENMARK),<br />
Carsten Sönksen, Christian Jørgensen, Ole Jensen<br />
Glycation Plasma Proteome In Gestational Diabetes Predisposed To Preeclampsia<br />
Cc Wang (The Chinese University of Hong Kong, CHINA), Cy Chu, Tcw Poon, Wh Tam,<br />
Cy Li, Ms Rogers<br />
Glycoproteomics Of Paclitaxel Chemoresistance In Ovarian Cancer Cell Lines<br />
Michela di Michele (Catholic University, ITALY), Anna della Corte, Lucia Cicchillitti,<br />
Piero del Boccio, Andrea Urbani, Cristiano Ferlini<br />
Withdrawn<br />
Glycoproteomics: Analysis Of Carbohydrate Msms Fragment Ion Spectra By<br />
Database Searching<br />
Matthias Glueckmann, Donna Potts (Applied Biosystems, GERMANY), Christof Lenz,<br />
Lydia Nuwaysir, Ningombam Sanjib Meitei, Radha Nigam, Kamal Kishore<br />
Glycan Analysis By Capillary Electrophoresis Coupled To High Resolution Mass<br />
Spectrometry<br />
Carolin Huhn (Aalen University, GERMANY), L Renee Ruhaak, André M. Deelder,<br />
Manfred Wuhrer, Christian Neusüß<br />
112 113
P-TUE-202<br />
Glycomics Of Dmbt1sag: Potential Bacterial Binding Of Identified<br />
Polyfucosylated Lewis Type O-Linked Glycans<br />
Samah Issa (National University of Ireland Galway, IRELAND), Niclas Karlsson,<br />
Antoon Ligtenberg<br />
P-TUE-215<br />
A High Througput Sample Preparation Method For N-Glycan Profiling Of Plasma<br />
Glycoproteins<br />
L Renee Ruhaak (Leiden University Medical Center, THE NETHERLANDS), Manfred<br />
Wuhrer, Carolien A.M. Koeleman, Cornelis H. Hokke, Andre M. Deelder<br />
P-TUE-203<br />
De Novo Glycan Structure Search With Cid Ms/Ms Spectra Of Native<br />
N-Glycopeptides<br />
Hannu Peltoniemi (Medicel Ltd, FINLAND), Sakari Joenväärä, Risto Renkonen<br />
P-TUE-216<br />
Comparative Glycoproteomics Of Campylobacter Jejuni: An Insight Into Clinical<br />
Differences<br />
Nichollas Scott (University of Sydney, AUSTRALIA), Stuart Cordwell<br />
P-TUE-204<br />
P-TUE-205<br />
P-TUE-206<br />
P-TUE-207<br />
P-TUE-208<br />
P-TUE-209<br />
P-TUE-210<br />
N-Glycoproteomics - An Automated Workflow Approach<br />
Sakari Joenväärä (Medicel Ltd, FINLAND), Ilja Ritamo, Hannu Peltoniemi, Risto Renkonen<br />
Human Salivary Mucins: Mg2 (Muc7) Glycosylation Is Consistent, Whereas<br />
Mg1 (Muc5b) Glycosylation Varies Extensively Between Healthy Individuals<br />
Niclas Karlsson (Centre for Bioanalytical ScIences, Nui Galway, IRELAND), Kristina<br />
Thomsson, Nicolle Packer<br />
Glycoproteins Expressed Differentially In Mouse Exposed By Mercury Chloride<br />
Bong-Hwa Kim (Department of Molecular Medicine, KOREA), Hee-Young Son, Pyong-<br />
Gon Moon, Hong-Bae Jeon, Mi-Na Song, Sang-Hyun Kim, Moon-Chang Baek<br />
Improved Glycopeptide Profiling Of Pharmaceutical Compounds By Novel<br />
Enrichment Strategies<br />
Peter Leland (Emd Chemicals, Inc., UNITED STATES), Jessica Wohlgemuth, Thomas<br />
Eichhorn, Christian Hunzinger, Robertus Hendriks, Sven Andrecht<br />
Glycoblotting For Quantitative N- And O-Glycomics In Disease Diagnosis<br />
Yoshiaki Miura (Hokkaido University, JAPAN), Yasuro Shinohara, Jun-Ichi Furukawa,<br />
Shin-Ichiro Nishimura<br />
Mass Spectrometric Study Of Fgf-2 Glycation<br />
Helen Montgomery (Koichi Tanaka Mass Spec. Research Lab., Shimadzu, UNITED<br />
KINGDOM), Omar Belgacem, A Qadeer, Nessar Ahmed<br />
Boronic Acid Lectin Affinity Chromatography (Blac) In Glycoproteomics<br />
Alex Monzo (Horvath Laboratory of Bioseparation Sciences, AUSTRIA), Marcell<br />
Olajos, Lorenzo De Benedictis, Guenther Bonn, Andras Guttman<br />
P-TUE-217<br />
P-TUE-218<br />
P-TUE-2<strong>19</strong><br />
P-TUE-220<br />
P-TUE-221<br />
P-TUE-222<br />
Disease Related Changes In The Glycosylation Pattern Of Serum Igg Analyzed By<br />
Maldi-Tof Ms<br />
Katrin Sparbier, Hassan Dihazi, Sabine Blaschke, Gerd-Anton Mueller, Thomas Flad,<br />
Markus Kostrzewa (Bruker Daltonik GmbH, GERMANY)<br />
Effect Of Glycosylation On The Extracellular Domain Of The Ag43 Bacterial<br />
Autotransporter<br />
Allan Stensballe (University of Aalborg, DENMARK), Daniel Otzen, Stine K. Knudsen<br />
Quantitative Proteomic Approach To Profile Phosphorylation And Glycosylation<br />
Changes In Mammalian Cells In Response To Hypoxia Treatment<br />
Safia Thaminy (Institute for Systems Biology, UNITED STATES), Yong Zhou, Mi-Youn<br />
Brusniak, Ning Zhang, Jingchun Chen, Simon Letarte, Carey Sheu, Julian Watts,<br />
Ruedi Aebersold<br />
High-Sensitivity Nano- And Capillary-Lc/Ms For Mucin O-Glycan Profiling<br />
Kristina Thomsson (Institute of Biomedicine, Göteborg University, SWEDEN), Malin<br />
Bäckström, Hasse Karlsson, Gunnar C. Hansson<br />
A Proteomic Approach To Detect Galectin-3 Ligands From Human Neutrophils<br />
Gisele Tomazella (Centro de Química de Proteínas - Unfesp, BRAZIL), Gustavo de<br />
Souza, Idalete da Silva, Harald Wiker, Roger Chammas, Lewis Greene<br />
Sweet Success: Characterizing O-Glcnac Sites With Electron Transfer<br />
Dissociation Ms<br />
Namrata Udeshi (Department of Chemistry, University of Virginia, UNITED STATES),<br />
Youn-Cheon Kim, Michael Housley, Gerald Hart, Neil Olszewski, Jeffrey Shabanowitz,<br />
Donald Hunt<br />
P-TUE-211<br />
P-TUE-212<br />
P-TUE-213<br />
Spot The Difference: What Is A Normal Glycomic Profile?<br />
Nicolle Packer (Macquarie University, AUSTRALIA), Pia Hønnerup-Jensen, Daniel<br />
Kolarich<br />
Mass Spectrometric Characterization Of Glycosylation In Antiophidic Proteins<br />
Dm43 and Dm64<br />
Ileana R. León, Jonas Perales (Oswaldo Cruz Foundation-Fiocruz / Rio De Janeiro<br />
Proteomic Network, BRAZIL), Ana G.C. Neves-Ferreira, Surza L.G. Rocha, Monique<br />
R.O. Trugilho, Daniela G. Beghini, Richard H. Valente<br />
Study Of Glycations Of Barley Lipid Transfer Proteins<br />
Inga Petry-Podgorska (Institute of Analytical Chemistry of The Ascr, CZECH<br />
REPUBLIC), Karel Mazanec, Janette Bobalova<br />
P-TUE-223<br />
P-TUE-224<br />
P-TUE-225<br />
N-Glycome Of Mesenchymal Stem Cells Can Be Used To Evaluate Cellular<br />
Differentiation<br />
Leena Valmu (Finnish Red Cross Blood Service, FINLAND), Suvi Natunen, Tero<br />
Satomaa, Annamari Heiskanen, Jari Natunen, Sari Tiitinen, Ulla Impola, Petri<br />
Lehenkari, Juhani Saarinen<br />
Withdrawn<br />
Automatic Interpretation Strategy For Ms-Based Analysis Of Standard<br />
Glycoproteins<br />
Yang Zhang (Institutes of Biomedical Sciences, Fudan University, CHINA)<br />
P-TUE-214<br />
Glycoproteomics: Applications For Stem Cell And Cancer Biomarkers<br />
Michael Pierce (Center for Biomedical Glycomics, Complex Carbohydrate Research<br />
Center, University of Georgia, UNITED STATES), Steven Dalton, Kelley Moremen,<br />
Michael Tiemeyer, Lance Wells, Ron Orlando, Karen Abbott, Gerardo Alvarez-Manilla,<br />
William York<br />
114 115
Mass Spectrometric Innovations<br />
P-TUE-226<br />
P-TUE-227<br />
P-TUE-228<br />
P-TUE-229<br />
P-TUE-230<br />
P-TUE-231<br />
Enhancing Linear Ion Trap Mass Spectrometry Etd Performance Using<br />
Supplemental Activation<br />
Zhiqi Hao, Jae Schwartz, John Syka, Andreas Huhmer (Thermo Fisher Scientific,<br />
UNITED STATES)<br />
Characterization Of Small Molecule-Protein Interaction Site By Combined<br />
Scanning Mode-Ion Filtering In A Hybrid Triple Quadrupole<br />
Enrique Calvo (Cnic, SPAIN), Emilio Camafeita, Juan Antonio Lopez<br />
N-Terminal Plasma Profiling In Biomarker Discovery<br />
Gemma Davidson (University of Liverpool, UNITED KINGDOM), Lucy Mcdonald,<br />
Duncan Robertson, Robert Beynon<br />
Metal-Imaging Mass Spectrometry (Mims): An Imaging Mass Spectrometry<br />
Technology To Determine The Distribution Of Metal Ions In Tissue Samples.<br />
Philip Doble (University of Technology Sydney, AUSTRALIA)<br />
Optimization Of Intact Pprotein Funnel-Skimmer Dissociation For Ftms<br />
Jennifer S. Cobb, Michael L. Easterling (Bruker Daltonics Inc., UNITED STATES),<br />
Jeffrey N. Agar<br />
Mass Spectrometric Analysis Of Plasma Proteins Using An Experimental Design:<br />
Challenges & Perspectives<br />
Srinubabu Gedela (Andhra University College of Engineering, India), Appa Rao Allam<br />
P-TUE-239<br />
P-TUE-240<br />
P-TUE-241<br />
P-TUE-242<br />
P-TUE-243<br />
P-TUE-244<br />
Full Automation Of Sample Preparation On Maldi Targets Using Stagetips<br />
Christopher Loessner (German Cancer Research Center, GERMANY), Heinrich<br />
Gausepohl, Martina Schnolzer<br />
A Simple And Efficient Concept For Etd and Ptr In A Spherical Ion Trap<br />
Ralf Hartmer, Markus Lubeck (Bruker Daltonik GmbH, GERMANY), Andreas<br />
Brekenfeld, Carsten Baessmann, Arnd Ingendoh<br />
Hplc–Ms Analysis Of Large Peptides And Intact Proteins Using Etd and Ptr<br />
Ion/Ion Reactions<br />
Andreas Leinenbach, Markus Lubeck, Ralf Hartmer, Carsten Baessmann, Christian<br />
Huber, Christian Albers (Bruker Daltonik, GERMANY)<br />
Combination Of Lc-Ms and Lc-Ms/Ms Datasets In Bottom-Up Proteomics<br />
Magnus Palmblad (Leiden University Medical Center, THE NETHERLANDS), Yuri van<br />
der Burgt, Hans Dalebout, André Deelder<br />
Lc/Ms Intact Mass Analysis Of Immunoglobulin Gamma Antibodies By Ltq-<br />
Orbitrap<br />
Pavel V. Bondarenko, Tonya Pekar Second (Thermo Fisher, UNITED KINGDOM), Vlad<br />
Zabrouskov, Alexander A. Makarov, Zhongqi Zhang<br />
An Ipg Mudpit Workflow For Ms Analysis Of Protein Complexes Purified By Blue<br />
Native Gels<br />
Mahbod Hajivandi (Invitrogen, UNITED STATES), Thomas Beardslee, Xiquan Liang,<br />
Paul Predki, R Marshall Pope<br />
P-TUE-232<br />
P-TUE-233<br />
P-TUE-234<br />
P-TUE-235<br />
P-TUE-236<br />
P-TUE-237<br />
Analyzing Plasma Proteome With Electron Transfer Dissociation And Proton<br />
Transfer Reaction<br />
Sarah Hart (University of Manchester, UNITED KINGDOM), Richard Blankley,<br />
Carsten Baessmann, Markus Lubeck, Laura Main, Simon Gaskell<br />
Evaluation Of Etd In A Hybrid Qh-Ftms Proteins<br />
Michael Easterling, Ralf Hartmer (Bruker Daltonik GmbH, GERMANY), Jiong Yang,<br />
Melvin A. Park<br />
Improved Coverage In Global Bottom Up Proteomics Survey Experiments By<br />
Decreasing Cycle Time On A Linear Ion Trap Mass Spectrometer<br />
Julian Phillips (Thermo Fisher Scientific, UNITED STATES), Julie Horner, Amy<br />
Zumwalt, Andreas Huhmer<br />
Optimization Of Parameters For Protein And Peptide Analysis Using High Field<br />
Asymmetric Waveform Ion Mobility Spectrometry (Faims)<br />
Julie Hornerr (Thermo Fisher Scientific, UNITED STATES), Sucharita Dutta, Julian<br />
Phillips, Mark Sanders<br />
Using Ims To Separate Precursors From Species Of Different Charges In Tandem<br />
Ms Analyses<br />
Chris Hughes (Waters Ms Technologies Centre, Manchester, UNITED KINGDOM),<br />
Therese Mckenna, Jim Langridge<br />
Specific Maldi Imaging Using Oligonucleotides, Antibodies And Lectins<br />
Amelie Laure Jacquet (Maldi Imaging Team Ustl, FRANCE), Mohamed El Ayed,<br />
Marchald Deschamp, I Rudolff, GG Proess, Maxence M. Wisztorski, Isabelle Fournier,<br />
Michel Salzet<br />
P-TUE-245<br />
P-TUE-246<br />
P-TUE-247<br />
P-TUE-248<br />
P-TUE-249<br />
P-TUE-250<br />
Imaldi+: A Targeted Proteomics Approach To Clinical Diagnostics<br />
Brinda Shah (Uvic Genome Bc Proteomics Centre / University of Victoria, CANADA),<br />
Jennifer Reid, Christoph Borchers<br />
Unprecedented Mass Accuracy Using Orbitrap Mass Spectrometry<br />
Richard Scheltema (University of Groningen, THE NETHERLANDS), David Wildridge,<br />
Michael Barrett, Ritsert Jansen, Rainer Breitling<br />
Continuously Monitoring The States Of Tryptic Digestion Processes Of Proteins<br />
By Ambient Liquid Mass Spectrometry (Alms)<br />
Jentaie Shiea, Cheng-Hui Yuan (Department of Chemistry, National Sun Yat-Sen<br />
University, TAIWAN), Jingyueh Jeng, Chih-Yuan Cheng, Li-Hua Lo<br />
Nano-Esi And Ion Trap-Etd/Ptr-Ms/Ms For The Analysis Of Post-Translational<br />
Modifications<br />
Frank Sobott (Oxford University, UNITED KINGDOM)<br />
Targeted Assignment Of Protein N- And C-Termini In Protein Samples By A<br />
Comprehensive Top-Down Lc-Maldi-Isd Sequencing Strategy<br />
Detlev Suckau (Bruker Daltonics, GERMANY), Anja Resemann<br />
Fast And Accurate Determination Of Monoisotopic Masses Of Polypeptides From<br />
Ftms<br />
Kunsoo Park, Joo Young Yoon, Sunho Lee, Eunok Paek (University of Seoul, KOREA),<br />
Heejin Park, Sang-Won Lee<br />
P-TUE-238<br />
A New Peptide Profiling Technology For Early Diagnosis And Personalized Medicine<br />
Lyang-Ja Lee (Protosera Inc., JAPAN), Kenji Tanaka, Nobuya Sanuki, Ushio Takeda,<br />
Kazuhiro Ishida, Teruto Hashiguchi, Ikurou Maruyama<br />
116 117
Phosphoproteomics<br />
P-TUE-251<br />
P-TUE-252<br />
P-TUE-253<br />
Evaluation Of Chemical Beta-Elimination For Analysis Of Phosphorylated Peptides<br />
Nicolai Bache (University of Southern Denmark, DENMARK), Martin Røssel Larsen<br />
Cerebrospinal Fluid Phosphoproteome Investigated Using Tio2 Chromatography<br />
And Mass Spectrometry<br />
Justyna Bahl (Statens Serum Institut, Dpt. of Autoimmunology, DENMARK), Søren<br />
Jensen, Martin Larsen, Niels Heegaard<br />
A Comprehensive Phosphoproteome Workflow<br />
Roger G. Biringer (Thermo Fisher Scientific, UNITED STATES), Zhiqi Hao, Michael G.<br />
Harrington, Andreas F.R. Hühmer<br />
P-TUE-263<br />
P-TUE-264<br />
P-TUE-265<br />
Serine 395, Controls Transcriptional Activity In The Aryl Hydrocarbon Receptor<br />
Alan Friedman (University of Rochester, UNITED STATES), Brent Kobielush, Gary<br />
Minsavage, Daria Vorojeikina, Mike Easterling, Thomas Gasiewicz<br />
Phosphoproteome Profiling Of Human Lung Cancer<br />
Angelo Gámez-Pozo (Hospital Universitario La Paz, SPAIN), Iker Sánchez-Navarro,<br />
Enrique Calvo, Manuel Nistal, JavIer de Castro, Enrique Espinosa, Juan Antonio<br />
López, Manuel González-Barán, Juan Ángel Fresno Vara, E Camafeita<br />
Protein Phosphorylation Characterization By Maldi-Tof Mass Spectrometry<br />
With The Improved Matrix Layer Sample Preparation<br />
Ignazio Garaguso (Fraunhofer Institute of Toxicology and Experimental Medicine,<br />
GERMANY), Juergen Borlak<br />
P-TUE-254<br />
P-TUE-255<br />
P-TUE-256<br />
P-TUE-257<br />
P-TUE-258<br />
P-TUE-259<br />
Automated Serum Phosphopeptide Profiling Of Glaucoma Patients<br />
Nils Boehm (Experimental Ophthalmology, Department of Ophthalmology, University<br />
of Mainz, GERMANY), Joachim Richter, Susanne Rosfa, Stephanie Joachim, Norbert<br />
Pfeiffer, Franz Grus<br />
Phosphorylation-Specific Interaction And Regulation Of Vasp In Platelets<br />
Julia Burkhart (Protein Mass Spectrometry and Functional Proteomics Group<br />
Rudolf-Virchow-Center, GERMANY), Thomas Premsler, Peter Benz, Michaela Kuhn,<br />
Thomas Renné, Albert Sickmann<br />
First Round And Second Round Search Engines For Analyzing Post-Translational<br />
Modifications Such As Phosphorylation<br />
M Blueggel, LM Freimark, RJ Shaw, DC Chamrad, C Huels (Protagen Ag, GERMANY),<br />
JM Asara<br />
Phosphoproteomic Analysis Of Oxidative Stress In Epithelial Cells: Major Role Of<br />
Src Kinase-Dependent Phosphorylation In Regulating Adhesion<br />
Hong-Lin Chan, Hsiu-Chuan Chou, Jana Gruenewald, Michael Waterfield, Anne Ridley,<br />
John Timms (Ega Institute for Women’s Health, University College London, UNITED<br />
KINGDOM)<br />
Quantitative Phosphoproteome Analysis Applied To The Human Neural Stem Cell<br />
Kun Cho (Mass Spectrometry Research Team, Korea Basic Science Institute,<br />
KOREA), Eunmin Kim, Gun Wook Park, Jeong Hwa Lee, Yeong Hee Ahn, Kyung-Hoon<br />
Kwon, Jin Young Kim, Kyung Hee Byun, Bong Hee Lee, Jong Shin Yoo<br />
Anchoring Phosphorylation To Surfaces For Localisation And Enrichment Studies<br />
Garry Corthals (Turku Centre for Biotechnology / University of Turku/ Åbo Akademi<br />
University, FINLAND), Petri Kouvonen, Susumu Imanishi, John Eriksson, Eeva Rainio,<br />
Päivi Koskinen, Anne Rokka, Mika Linden, Jan-Henrik Smått<br />
P-TUE-266<br />
P-TUE-267<br />
P-TUE-268<br />
P-TUE-269<br />
P-TUE-270<br />
P-TUE-271<br />
P-TUE-272<br />
Strategies For Finding The Most Important Phosphorylation Sites In A Protein<br />
Mark Graham (Children’s Medical Research Institute, AUSTRALIA), Ling Chan, Phillip<br />
Robinson<br />
Quantification Of Tyrosine Phosphorylation By Affinity Enrichment And Isotopic Labelling<br />
Peter Hoffmann (University of Adelaide, AUSTRALIA), Mark R. Condina, Shaun R. Mccoll<br />
Cid And Etd Analysis Of Kinase Sites Of Phosporylation With High Mass<br />
Accuracy Measurement<br />
Martin Hornshaw (Thermo Fisher Scientific, UNITED KINGDOM), Kai Scheffler,<br />
Martin Zeller, Nick Morrice<br />
Phosphoproteomic Signature In Lung Cancer Metastasis Revealed By A Label-<br />
Free Strategy<br />
Chuan-Chih Hsu (Department of Chemistry, National TAIWAN University / Institute of<br />
Chemistry, Academia Sinica, TAIWAN), Yi-Ting Wang, Chia-Feng Tsai, Pei-Yi Lin, Tzu-<br />
Chan Hong, Chih-Chiang Tsou, Wen-Lian Hsu, Ting-Yi Sung, Tze-Min Hong, Yu-Ju Chen<br />
Phosphoproteome Analysis Of Estrogen-Induced Breast Cancer Cell Signaling<br />
Koshi Imami (Institute for Advanced Biosciences, Keio University, JAPAN), Naoyuki<br />
Sugiyama, Yutaka Kyono, Masaru Tomita, Yasushi Ishihama<br />
Comparative Cid and Etd Of Enriched Hydrophobic Peptides Of H. Salinarum<br />
Membrane Proteins<br />
Arnd Ingendoh (Bruker Daltonik GmbH, GERMANY), Christian Klein, Frank Siedler,<br />
Dieter Oesterhelt, Beatrix Scheffer, Friedhelm Peiffer<br />
Acidic Amino Acid Modifications In Proteins/Peptides From Frog Skin Secretion<br />
Lene A. Jakobsen (University of Southern Denmark, DENMARK), Tianbao Chen, Chris<br />
Shaw, Martin R. Larsen<br />
P-TUE-260<br />
Proteomics Screen To Identify 14-3-3 Binding Partners Regulated By Insulin<br />
Fanny Dubois (Mrc Protein Phosphorylation Unit, UNITED KINGDOM), Franck<br />
Vandermoere, Rachel Toth, Nicholas Morrice, Carol Mackintosh<br />
P-TUE-273<br />
A New Sample Prep Tool For Enrichment Of Phospho-Peptides Using Phos Spintrap Fe<br />
Lena Jonsson (Ge Healthcare, SWEDEN), Johan Öhman, Ann-Marie Nissfolk, Marika<br />
Sjödahl, Inger Salomonsson, Ulf Hellberg, Helena Hedlund<br />
P-TUE-261<br />
P-TUE-262<br />
Comparative Analysis Of The Human Kinome Phosphorylation At Distinct Mitotic<br />
Stages<br />
Kalyan Dulla (Dept of Cell Biology, Max Planck Institute of Biochemie, GERMANY),<br />
Henrik Daub, Renate Hornberger, Albert Ries, Erich A. Nigg, Roman Körner<br />
Comprehensive Strategy For Characterization Of Phosphorylation Events In The<br />
Il-1β Pathway<br />
Kasper Engholm-Keller (University of Southern Denmark, DENMARK), Søren Skov<br />
Jensen, Flemming Pociot, Martin Røssel Larsen<br />
P-TUE-274<br />
P-TUE-275<br />
Array Based Protein Expression Analysis Cell Signalling In Murine Hepatocellular<br />
Carcinomas<br />
Thomas Knorpp (Nmi - Natural and Medical Sciences Institute at The University of<br />
Tübingen, GERMANY), Berthold Gierke, Philip Marx-Stölting, Michael Pawlak, Michael<br />
Schwarz, Markus F. Templin<br />
Performing Phosphopetide Analysis On A Titanium Dioxide Based Enrichment And<br />
Separation Chip<br />
Karsten Kraiczek (Utrecht University Biomolecular Ms and Proteomics Group, GERMANY),<br />
Shabaz Mohammed, Martijn Pinkse, Reinout Raijmakers, Tom van de Goor, Albert<br />
Heck, Simone Lemeer<br />
118 1<strong>19</strong>
P-TUE-276<br />
Dissection Of The Insulin And Igf-1 Signaling Pathways By Quantitative Proteomics<br />
Irina Kratchmarova (Dep. of Biochemistry and Molecular Biology, University of<br />
Southern Denmark, DENMARK)<br />
P-TUE-288<br />
Enrichment And Separation Of Phosphopeptides Using Free Flow Electrophoresis<br />
Mikkel Nissum, Sabine Kronbauer, Robert Wildgruber (Bd Diagnostics, GERMANY),<br />
Craig Gelfand, Christoph Eckerskorn, David Craft<br />
P-TUE-277<br />
Arthritis-Inducible Protein, Annexin Vii: High Phosphorylation In Rheumatoid Arthritis<br />
Manae Kurokawa (Clinical Proteomics & Molecular Medicine, St. Marianna University<br />
School of Medi, JAPAN), Kosuke Matsuo, Hiroshi Nakamura, Kayo Masuko, Kazuki<br />
Okamoto, Tomohiro Kato<br />
P-TUE-289<br />
Global Phosphopeptide Profiling In Lncap-Cells<br />
Heike Piechura (Medizinisches Proteom-Center, Ruhr-Universitaet Bochum,<br />
GERMANY), Sebastian WIese, Christian Bunse, Eva M. Neuhaus, Hanns H. Hatt,<br />
Helmut E. Meyer, Bettina Warscheid<br />
P-TUE-278<br />
P-TUE-279<br />
P-TUE-280<br />
P-TUE-281<br />
P-TUE-282<br />
P-TUE-283<br />
P-TUE-284<br />
Quantitative Phosphoproteomics Of Depolarized Nerve Terminals.<br />
Martin R. Larsen (University of Southern Denmark, DENMARK), Mark E. Graham,<br />
Phillip J. Robinson<br />
Discovery Of Phosphoprotein Hepatocellular Carcinoma Biomarkers Using A Fully<br />
Automated Tio2-Based 3dlc (Scx/Tio2/C18)-Ms/Ms Method<br />
Hyoung-Joo Lee (Yonsei Proteome Research Center, Biomedical Proteome Research<br />
Center, Department of Biochemistry, KOREA), Keun Na, Min-Seok Kwon, Min-Jeong<br />
Kang, Hoguen Kim, Young-Ki Paik<br />
Novel Tyrosine Kinase Substrates In Oncogenic Egf Signaling And Breast Cancer<br />
Development<br />
Yoon Pin Lim (National University of Singapore, Singapore), Yunhao Chen, Lee Yee<br />
Choong, Qingsong Lin, Robin Philp<br />
Targeted Srm Assays Of Cell Lysate Phosphopeptides Enriched By Automated,<br />
Magnetic Bead-Based System<br />
Mary F. Lopez, Bryan Krastins (Thermofisher Scientific, UNITED STATES), David<br />
Sarracino, John Rogers, Paul Haney, Michael Athanas, Amol Prakash<br />
Insulin Dosages Mediate Irs-1 Phosphorylation Patterns That Are Associated<br />
With Positive And Negative Signaling Effects<br />
Xiao-Ming Lu (Massachusetts General Hospital, Harvard Medical School / The<br />
Shriners Hospital for Children, UNITED STATES), Amy Lu, Edward Carter, Joseph<br />
Avruch, Ronald Tompkins, Alan Fischman<br />
Enhanced Phosphopeptide Detection And Sequencing Using Uplc With A Tandem<br />
Quadrupole<br />
Therese Mckenna, Daniel J. Kenny, James I. Langridge (Waters Corporation, UNITED<br />
KINGDOM)<br />
Characterization Of Foxm1 Phosphorylation Sites Using Online Tio2<br />
Phosphopeptide Enrichment<br />
Jamila Laoukili, Monica Alvarez, Lars Meijer (Department of Physiological Chemistry and<br />
Centre for Biomedical Genetics, University Medical Center Utrecht, THE NETHERLANDS),<br />
Marie Stahl, Shabaz Mohammed, Livio Kleij, Albert Heck, René Medema<br />
P-TUE-290<br />
P-TUE-291<br />
P-TUE-292<br />
P-TUE-293<br />
P-TUE-294<br />
P-TUE-295<br />
P-TUE-296<br />
Characterization Of Imac And Tio2 In The Study Of Dynamic Regulation Of<br />
Phosphorylation<br />
Xiquan Liang (Invitrogen, UNITED STATES), Gier Fonnum, Mahbod Hajivandi, Torkel<br />
Stene, Nini H. Kjus, Erlend Ragnhildstveit, Joseph W. Amshey, Paul Predki, R<br />
Marshall Pope<br />
Phosphorylation-Specific Interaction And Regulation Of Vasodilator-Stimulated<br />
Phosphoprotein<br />
Thomas Premsler (Rudolf-Virchow-Center for Experimental Biomedicine, Protein<br />
Mass Spectrometry, University of Wuerzburg, GERMANY), Julia Maria Burkhart,<br />
Albert Sickmann, Peter Benz, Thomas Renné, Michaela Kuhn<br />
Analysis Of Stoichiometry Of Protein Phosphorylation In Adipocyte Lipid<br />
Droplets By Isotopic Tagging<br />
Alexey Pshezhetsky (Deps of Pediatrics And Biochemistry, University of Montreal<br />
/ Department of Medical Genetics, Sainte-Justine Hospital, CANADA), Eugenii<br />
Kanshin, Shu Pei Wang, Mila Ashmarina, Grant Mitchell, Ilya Nifant’ev<br />
Imatinib Resistance In Cml Is Caused By Bcr-Abl-Independent Activation Of<br />
Raf<br />
Julia Rosenhahn (Institute of Human Genetics and Anthopologie, Friedrich Schiller<br />
University Jena, GERMANY), Ignacio Rubio, Christina Hipler, Ivan F. Loncarevic,<br />
Ferdinand von Eggeling<br />
Multiple Protease Digestion Using Immobilized Enzymes: An Effective Sample<br />
Preparation Method For The Protein Structural Analysis By Mass Spectrometry.<br />
Yukie Sasakura (Hitachi High-Technologies, JAPAN), Ayumi Suzuki, Katsuhiro Kanda,<br />
Izumi Waki<br />
Plant Phosphoproteome By Hydroxy Acid-Modified Metal Oxide Chromatography<br />
(Hammoc)<br />
Naoyuki Sugiyama (Institute for Advanced Biosciences, Keio University / Human<br />
Metabolome Technologies, Inc., JAPAN), Hirofumi Nakagami, Sumiko Ohnuma, Keiichi<br />
Mochida, Arsalan Daudi, Masaru Tomita, Ken Shirasu, Yasushi Ishihama<br />
Withdrawn<br />
P-TUE-285<br />
Online Automated Phosphoproteomics Using Tio2<br />
Martijn Pinkse, Shabaz Mohammed, Martina O’Flaherty (Biomolecular Mass<br />
Spectrometry and Proteomics Group, Utrecht University, THE NETHERLANDS),<br />
Simone Lemeer, Albert Heck<br />
P-TUE-297<br />
Targeting Biologically Important But Poorly Ionized Phosphopeptides Using Lc/<br />
Mrm/Ms/Ms<br />
Lorne Taylor (Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, CANADA),<br />
Andreas Traweger, Brett Larsen, David Cox, Stephen Tate, Tony Pawson<br />
P-TUE-286<br />
P-TUE-287<br />
Phosphoproteomic Analysis Of 3 Distinct Tumor Cell Lines Arrested At M-Phase<br />
Kohji Nagano (Chugai Pharmaceutical Co., Ltd., JAPAN), Takashi Shinkawa, Osamu<br />
Kondoh, Sayuri Morimoto, Noriyuki Inomata, Nobuya Ishii, Yuko Aoki, Masayuki<br />
Haramura<br />
Protein Phosphorylation Analysis And Quantification Of Mice Kidney Proteins By<br />
2d-DpAge And Icp-Ms<br />
Boris Neumann (Proteome Factory Ag, GERMANY), Karola Lehmann, Jens Altvater,<br />
Robert Ahrends, Franz Theuring, Christian Scheler<br />
P-TUE-298<br />
P-TUE-299<br />
Titanium Dioxide Coated MAldi Plate For On Target Analysis Of Phosphopeptides<br />
Federico Torta (San Raffaele Scientific Institute, ITALY), Angela Bachi, Matteo Fusi,<br />
Carlo S. Casari, Carlo E. Bottani<br />
Serine 395, Imporant For Transcriptional Activity In Mouse-Ahr, Is<br />
Phosphorylated By Pka<br />
Alan Friedman, Michael Easterling, Patrick van Houts (Bruker Daltonics Inc., UNITED<br />
STATES), Brent R. Kobielush, Daria Vorojeikina, Thomas A. Gasiewicz<br />
120 121
P-TUE-300<br />
P-TUE-301<br />
Evaluation Of The Low-Specificity Protease Elastase For Phosphoproteome<br />
Analysis<br />
Bin Wang (Max Planck Institute for Biochemistry, GERMANY), Rainer Malik, Albert<br />
Ries, Erich A. Nigg, Roman Körner<br />
Analysis Of Phosphopeptides By Alkaline Phosphatase Reactor And Micro-Hplc-<br />
Esi-Ms/Ms<br />
Hui Wang (Dalian Institute of Chemical Physics, Chinese Academy of Sciences,<br />
CHINA), Jicheng Duan, Zhen Liang, Lihua Zhang, Yukui Zhang<br />
P-TUE-313<br />
P-TUE-314<br />
Rainer Breitling, Maarteen Koornneef, Ritsert Jansen<br />
Peptid Markers To Identify Wheat Allergens<br />
Tamas Janaky (Department of Medical Chemistry, University of Szeged, Hungary),<br />
Eva Gelencser, Attila Csorba, Krisztina Takacs, Jeno Szamos<br />
The Effects Of Peripheral And Central Administration Of Hypericum Perforatum<br />
L. On Chronic And Acute Pain<br />
Farzaneh Biranvand (Medical Sciences, Iran), Mojtaba Khaksarian<br />
P-TUE-302<br />
P-TUE-303<br />
Specific And Efficient Enrichment Of Phosphopeptides For Phospho-Proteome<br />
Analysis By Mass Spectrometry<br />
Paige Weis (Emd Chemicals, UNITED STATES)<br />
Optimization Of Immobilized Metal Ion Affinity Chromatography For Phosphopeptide<br />
Enrichment Prior To Mass Spectrometry<br />
Juanying Ye (Protein Research Group, Department of Biochemistry and Molecular<br />
Biology, University of Southern Denmark, DENMARK), Xumin Zhang, Peter Roepstorff,<br />
Ole Nørregaard Jensen<br />
P-TUE-315<br />
P-TUE-316<br />
Studty Of Photochemical And Antinociceptive Properties Of Medicinal Plant<br />
Allium Jesdianum And Probable Role Of The Opioidergic System<br />
Mojtaba Khaksarian (University of Medical Science, Iran), Bahram Delfan, Behroz<br />
Ahmadi<br />
Compared Proteomic Of The Flag Leaves Senescence Between Rice 93-11 And<br />
Nipponbare<br />
Qingtao Lu (Institute of Botany, CHINA / Institute of Plant Science, SWITZERLAND),<br />
Wei Li, Congming Lu<br />
P-TUE-304<br />
P-TUE-305<br />
P-TUE-306<br />
Withdrawn<br />
Tyrosine-Phosphorylated Proteins Are Predominantly Localized In The Glomerulus<br />
Of Normal Rat Kidney<br />
Ying Zhang (Department of Structural Pathology, Institute of Neprhology, Niigata<br />
Graduate School of Medical and Dental Sciences, JAPAN), Yutaka Yoshida, Bo Xu,<br />
Masaaki Nameta, Eishin Yaoita, Hidehiko Fujinaka, Tadashi Yamamoto<br />
Comparative Analysis Of Phosphoproteome Between Human Cerebellum And<br />
Prefrontal Cortex<br />
Ning Fu (Shanghai Institutes for Biological Sciences, CHINA), Jie Dai, Yi-Xue Li, Jia-<br />
Rui Wu, Philipp Khaitovich, Rong Zeng<br />
Plant Proteomics<br />
P-TUE-307<br />
P-TUE-308<br />
P-TUE-309<br />
P-TUE-310<br />
P-TUE-311<br />
Lead Induced Changes On Proteome Of Catharanthus Roseus (L.) G.Don<br />
Palanisamy Arun Mozhi Varman (Bharathidasan University, India)<br />
Fungal Proteomics<br />
Vijai Bhadauria (State Key Laboratory for Agrobiotechnology, China Agricultural<br />
University, CHINA), You-Liang Peng<br />
Rapid Bioinformatic Comparative Analysis Of Cold Shock TreaTed Rice Proteome<br />
John Chakel (Proxeon A/S, DENMARK), Alexandre Podtelejnikov, K Neilson, J Chick,<br />
Paul Haynes<br />
Dehydration Stress Responsive Comparative Proteome Of Lathyrus Sativus, A<br />
Hardy Legume<br />
Arnab Chattopadhyay, Aarti Pandey, Deepti Bhushan, Lalit Agrawal, Asis Datta,<br />
Subhra Chakraborty, Niranjan Chakraborty (National Institute for Plant Genome<br />
Research, India)<br />
Mass Spectrometry Studies Of S-Nitrosylated Peptides In Plant Proteomics<br />
Lisa Elviri (University of Parma, ITALY), Francesca Speroni, Emanuela Vurro, Maria<br />
Careri, Alessandro Mangia, Roberto de Michele, Michela Zottini, Fiorella lo Schiavo<br />
P-TUE-317<br />
P-TUE-318<br />
P-TUE-3<strong>19</strong><br />
P-TUE-320<br />
P-TUE-321<br />
P-TUE-322<br />
The Changes In The Phospholipid Composition Of Nuclear Subfractions In Treated<br />
By Non-Thermal Electromagnetic Radiation Wheat Seedlings<br />
Liya Alexandrovna Minasbekyan (Yerevan State University, Armenia)<br />
2de and 2d-Lc Analysis Of Wheat Line Taichung29*6/Yr5 Inoculated With<br />
Stripe Rust Race Cy32<br />
Yinghong Pan (Institute of Crop Science, Chinese Academy of Agricultural Sciences<br />
/ Nfcri, CHINA), Shichang Xiu, Cheng Ma, Jing Liu, Zhaohui Zhang, Ji Luo<br />
The Proteome Of Arabidopsis Thaliana Analyzed By Electron Transfer<br />
Dissociation Utilizing High Mass Accuracy Measurements<br />
Kai Scheffler (Thermo Fisher Scientific, Dreieich, GERMANY), Martin Hornshaw,<br />
Martin Zeller, Bernd Mueller<br />
Ion Mobility Coupled To NanOspray Lc Adds Another Dimension Of Separation<br />
For Complex Proteomics Samples<br />
Michaela Scigelova (Thermo Fisher Scientific, Dreieich, GERMANY), Gary Woffendin,<br />
Martin Hornshaw, Kai Scheffler, Bernd Mueller<br />
Digging Into The Plant Proteome<br />
Sergey Sikora (Genway Biotech, Inc., UNITED STATES), Xiangming Fang, Li Deng,<br />
Wei-Wei Zhang<br />
Profiling The Proteome Of Chlamydomonas Reinhardtii (Green Algae) Exposed To<br />
Multiple Stressors<br />
Marc Suter (Eawag, SWITZERLAND), Holger Nestler, René Schönenberger, Victor<br />
Nesatyy<br />
P-TUE-312<br />
Genetic Basis Of Proteome Variation In Arabidopsis<br />
Jingyuan Fu (Groningen Bioinformatics Centre, Groningen Biomolecular Sciences<br />
and Biotechnology Institute, University of Groningen, THE NETHERLANDS), Joost<br />
Keurentjes, Twan America, Richard Scheltema, Martijn Dijkstra, Dick Vreugdenhil,<br />
122 123
Proteomics Of Macromolecular Complexes<br />
P-TUE-323<br />
P-TUE-324<br />
P-TUE-325<br />
Analysis Of Nuclear Pore Complex Phosphorylation Sites Using A Maldi-Ltq<br />
Orbitrap Mass Spectrometer<br />
Justin Blethrow (Thermo Fisher Scientific, UNITED STATES), Rosa Viner, Vlad<br />
Zabrouskov, Joseph Glavy<br />
Analyses Of Proteasome Complexes And Proteome Variations In Acute Myeloid<br />
Leukemia Cells<br />
Mariette Matondo, Marie-Pierre Bousquet-Dubouch, Sandrine Uttenweiler-Joseph,<br />
Bernard Payrastre, Stéphane Manenti, Bernard Monsarrat, Odile Burlet-Schiltz<br />
(Institut de Pharmacologie et De Biologie Structurale, Cnrs, FRANCE)<br />
Mapping Human Protein Interaction Networks: The Human Proteotheque<br />
Initiative (Hupi)<br />
Benoit Coulombe (Institut de Recherches Cliniques de Montréal, CANADA), Philippe<br />
Cloutier, Annie Bouchard, Célia Jeronimo, Andrée-Anne Lacombe, Racha Al-Khoury,<br />
Mathieu Lavallée-Adam, Jack Greenblatt, Mathieu Blanchette, Diane Forget<br />
P-TUE-334<br />
P-TUE-335<br />
P-TUE-336<br />
P-TUE-337<br />
Quantitative Analysis Of C/Ebp{Alpha} Transcription Complexes In Leukemia<br />
Rositsa Koleva (Dana-Farber Cancer Institute, UNITED STATES), Scott Ficarro,<br />
Manor Askenazi, Jarrod Marto<br />
Shot-Gun Membrane Proteomics By Acid Hydrolysis Combined With Trypsin And<br />
Chymotrypsin<br />
Joseph Kwon (Proteome Research Team, Korea Basic Science Institute, KOREA),<br />
Jeehyun Oh, Sunghoon Lee, Seung Il Kim, Jong-Soon Choi<br />
Proteomics Study On Human Ccr4-Not: A Multi-Functional Complex Involved In<br />
Mrna Metabolism<br />
Nga-Chi Lau (Umc-Utrecht, THE NETHERLANDS), Annemieke Kolkman, Pim Pijnappel,<br />
Albert Heck, Marc Timmers<br />
Identification Of Protein Phosphorylation Sites Associated With Protein Complex<br />
Assembly Using An Imac-Based Proteomics Procedure<br />
Chang-Hung Lee (Institute of Biochemistry and Molecular Biology, National Yang-<br />
Ming University, TAIWAN)<br />
P-TUE-326<br />
Characterization Of A Novel Subunit Of The Drosophila Melanogaster Chromatin<br />
Remodeling Complex Pbap<br />
Jeroen Demmers (Erasmus Mc, THE NETHERLANDS), Gillian Chalkley, Yuri Moshkin,<br />
Karin Langenberg, Karel Bezstarosti, Andras Blastyak, Henrik Gyurkovics, Peter Verrijzer<br />
P-TUE-338<br />
Molecular Recognition In Oligomeric Enzymes: Integration Of Bioinformatic And<br />
Biosensoric Approaches<br />
Andrey Lisitsa (Institute of Biomedical Chemistry Rams, RUSSIAN FEDERATION), YU<br />
Mezentsev, P Ershov, A Molnar, A Ivanov, A Archakov<br />
P-TUE-327<br />
P-TUE-328<br />
P-TUE-329<br />
Differential Biotinylation To Study Influenza A Polymerase Subunit Pb1<br />
Heterodimerisation<br />
Mathias Dreger (Department of Physiology, Anatomy and Genetics, University of<br />
Oxford, UNITED KINGDOM), Tao Deng, George G. Brownlee<br />
Proteomics Of Protein Complexes: An Approach To Analyze Native Proteomes<br />
Oliver Drews (Department of Physiology, University of California Los Angeles,<br />
UNITED STATES), Yueju Wang, Emily Chen, Jun Zhang, John Yates 3rd, Peipei Ping<br />
Topology And Dynamics Of Protein Interaction Networks That Control Cell Growth<br />
Matthias Gstaiger (Institute of Molecular Systems Biology / Competence Center for<br />
Systems Physiology and Metabolic Diseases, SWITZERLAND), Oliver Rinner, Timo Glatter,<br />
Alexander Wepf, Irena Jevtov, Katja Köhler, Hugo Stocker, Ernst Hafen, Ruedi Aebersold<br />
P-TUE-339<br />
P-tue-340<br />
P-TUE-341<br />
Capture Of The Activated Fc Receptor Complex From The Surface Of Live Cells<br />
By Affinity Receptor Chromatography<br />
John Marshall (Ryerson University, CANADA), Peihong Zhu, Andy Jankowski<br />
Post-Translational Modifications Of The Endogenously Expressed Transcription<br />
Factors Tfiid and Saga<br />
N Mischerikow (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />
University, THE NETHERLANDS), AFM Altelaar, HTM Timmers, WWM Pijnappel, AJR<br />
Heck<br />
Spatiotemporal Changes Of Pka-Akap Complexes In Response To Prostaglandin E2<br />
Nikolaus Oberprieler (Biotechnology Centre of Oslo, University of Oslo, NORWAY),<br />
Thin Thin Aye, Knut Martin Torgersen, Albert Heck, Kjetil Tasken<br />
P-TUE-330<br />
P-TUE-331<br />
Pull-Downs Of Endogenously Expressed, Tagged Proteins For Interactions And<br />
Modifications<br />
Nina Hubner (Max-Planck Institute for Biochemistry, Dep. Proteomic and Signal<br />
Transduction, GERMANY), Johannes Graumann, Michiel Vermeulen, Alexander Bird,<br />
Ina Poser, Matthias Mann<br />
“Tagless” Strategy Of Protein Complex Identification: Towards High Throughput<br />
Jian Jin (Lawrence Berkeley National Laboratory, UNITED STATES), Lee Yang,<br />
Haichuan Liu, Ming Dong, Simon Allan, Steven Hall, Susan Fisher, John-Marc<br />
Chandonia, Mark Biggin, Ewa Witkowska, Peter Walian, Bing Jap, Terry C. Hazen<br />
P-TUE-342<br />
P-TUE-343<br />
Looking For E2f2 Transcription Factor Interacting Proteins<br />
Nerea Osinalde (Department of Biochemistry and Molecular Biology, University of<br />
The Basque Country, SPAIN), Kerman Aloria, Ana Zubiaga, Asier Fullaondo, Jesus M.<br />
Arizmendi<br />
Quantitative Phospho-Proteomics Elucidates Phosphorylation-Dependent<br />
Transcriptional Regulation Of The Yeast Mediator Complex<br />
Gideon Oudgenoeg (Biomolecular Mass Spectrometry and Proteomics Group,<br />
Utrecht University, THE NETHERLANDS), Manuel Tzouros, Joris Benschop, Tony<br />
Miles, Frank Holstege, JeroeN Krijgsveld<br />
P-TUE-332<br />
P-TUE-333<br />
Characterization Of Protein-Complexes Complementing Functional-Genomic<br />
Screens In Human Cell-Lines<br />
Magno Junqueira (Max Planck Institute of Molecular Cell Biology and Genetics -<br />
Dresden, GERMANY), Yusuke Toyoda, Mikolaj Slabicki, Zoltan Maliga, Mirko Theis,<br />
Dragomir Krastev, Frank Buchholz, Antony Hyman, Andrej Shevchenko<br />
Chromatin Proteome Demonstrates System-Wide Response To Replication<br />
Inhibition<br />
Guennadi A. Khoudoli (University of Dundee, UNITED KINGDOM), Peter J. Gillespie,<br />
Graeme X. Stewart, Jens S. Andersen, Jason R. Swedlow, J Julian Blow<br />
P-TUE-344<br />
P-TUE-345<br />
P-TUE-346<br />
Targeting Dynamic Changes Of The Cftr Interactome In Cystic Fibrosis<br />
Sandra Pankow (The Scripps Research Institute, UNITED STATES), Casimir<br />
Bamberger, William Balch, John R. Yates<br />
Cell Cycle Regulation Of Tbp Complexes In Human Cells<br />
Pim Pijnappel (Umc-Utrecht, THE NETHERLANDS), Annemieke Kolkman, Marijke<br />
Baltissen, Albert Heck, Marc Timmers<br />
Examination Of The Protein Complexes Bound On Gal Operon Promoter Of<br />
Thermoanaerobacter Tengcongensis<br />
Zhong Qian (Beijing Genomics Institute, Cas, CHINA), Fan Wei, Li Guo, Siqi Liu<br />
124 125
P-TUE-347<br />
Background Proteins In Immunoprecipitations: What Are They And How To<br />
Reduce Them<br />
Manfredo Quadroni (University of Lausanne, SWITZERLAND), Waridel Patrice,<br />
Bastienne Jaccard, Alexandra Potts<br />
P-TUE-361<br />
Identification Of Putative Complex I Assembly Factors By Blue Native Liquid<br />
Chromatography Ms/Ms<br />
JCT Wessels (Radboud University Nijmegen Medical Center, THE NETHERLANDS),<br />
RO Vogel, LP van den Heuvel, RJ Rodenburg, LG Nijtmans, JAM Smeitink, MH Farhoud<br />
P-TUE-348<br />
P-TUE-349<br />
P-TUE-350<br />
P-TUE-351<br />
P-TUE-352<br />
P-TUE-353<br />
P-TUE-354<br />
P-TUE-355<br />
P-TUE-356<br />
P-TUE-357<br />
P-TUE-358<br />
P-TUE-359<br />
P-TUE-360<br />
Optimized Immunoprecipitation And Co-Immunoprecipitation Using Dynabeads<br />
Elisabeth Breivold, David Gillooly, Paal Songe, Erlend Ragnhildstveit (Invitrogen Dynal<br />
As, NORWAY)<br />
Proteasome Diversity Analysed By Isotope Labelling And Protein Quantitation<br />
Reinout Raijmakers (Biomolecular Mass Spectrometry and Proteomics Group,<br />
Utrecht University, THE NETHERLANDS), Celia Berkers, Annemieke de Jong, Huib<br />
Ovaa, Shabaz Mohammed, Albert Heck<br />
Withdrawn<br />
Withdrawn<br />
Lc-Ms AnalysIs To Identify Ryanodine Receptor 1 (Ryr1) Protein-Protein Interactions<br />
Timothy Ryan (University of Toronto, CANADA)<br />
Quantitative 20s Proteasome Analysis From 5fu-Induced Apoptotic Jurkat T<br />
Cells By Silac, Sds-Page, And 2de Based Analysis<br />
Frank Schmidt (Helmholtz Centre, Leipzig, GERMANY), Alexander Kloos, Martin von<br />
Bergen, Burkhardt Dahlmann, Peter Jungblut, Bernd Thiede<br />
Proteomic Analysis Of Membrane Protein Complexes: Lessons From Affinity-<br />
Purified Ion Channels And Receptors<br />
Uwe Schulte (Logopharm GmbH, GERMANY), Catrin Müller, Wolfgang Bildl, Bernd Fakler<br />
Analysis Of Subunit Composition Of The 20s Proteasome Of Plasmodium Falciparum<br />
Nicole Sessler (Proteome Center Tübingen, University of Tübingen, GERMANY),<br />
Wolfgang Schütz, Rolf Fendel, Benjamin Mordmüller, Peter G. Kremsner, Tobias<br />
Lamkemeyer, Alfred Nordheim<br />
Comparative Mass Spectrometry Of The Endogenously Expressed Nuclear And<br />
Cytoplasmic Exosome<br />
Silvia Synowsky (Utrecht University, THE NETHERLANDS), Reinout Raijmakers, Albert Heck<br />
Identification Of Intracellular Molecules Interacting With The Stress-Induced,<br />
Psoriasis Susceptibility-Related Non-Coding Rna, Prins<br />
Krisztina Szegedi (Department of Dermatology and Allergology, University of<br />
Szeged, Hungary), Mária Antal, István Németh, Zsuzsanna Bata-Csörgõ, Attila<br />
Dobozy, Lajos Kemény, Márta Széll<br />
A Quantitative Proteomics Approach To Reveal Dynamics In Transcription Factor<br />
Complexes<br />
Marc Timmers (University Medical Centre Utrecht, THE NETHERLANDS), Florence<br />
Mousson, Petra de Graaf, Annemieke Kolkman, Pim Pijnappel, Bart Gevers<br />
Proteomic Analysis Of Ubxd1: Identification Of Novel Interaction Partners<br />
Julian Vasilescu (Ottawa Institute of Systems Biology, University of Ottawa,<br />
CANADA), Daniel Zweitzig, Dale Haines, Daniel Figeys<br />
Quantification Of Protein Complex Components In Interaction Networks<br />
Alexander Wepf (Institute for Molecular Systems Biology / Competence Center for<br />
Systems Physiology and Metabolic Diseases, SWITZERLAND), Timo Glatter, Ruedi<br />
Aebersold, Matthias Gstaiger<br />
P-TUE-362<br />
Contrasting Proteome Biology And Functional Heterogeneity Of The 20s<br />
Proteasome Complexes<br />
Glen Young (University of California, Los Angeles, united states), Aldrin Gomes,<br />
Yueju Wang, Peipei Ping<br />
Yeast Proteomics; Sparks For New Biology<br />
P-TUE-363<br />
P-TUE-364<br />
P-TUE-365<br />
P-TUE-366<br />
P-TUE-367<br />
P-TUE-368<br />
P-TUE-369<br />
P-TUE-370<br />
A New Approach To Achieving A Fast, In-Depth Biological Overview Of Yeast<br />
Proteomics Data<br />
Morten Bern (Proxeon A/S, DENMARK), John Chakel, Ole Vorm<br />
Comprehensive Curation And Analysis Of Global Interaction Networks<br />
Lorrie Boucher (Samuel Lunenfeld Research Institute, Toronto, CANADA), Teresa<br />
Reguly, Bobby-Joe Breitkreutz, Chris Stark, Rose Oughtred, Michael Livstone,<br />
Ashton Breitkreutz, Valerie Wood, Kara Dolinski, Mike Tyers<br />
Interrogation Of The Tor Signaling Network In Budding Yeast<br />
Ashton Breitkreutz (Samuel Lunenfeld Research Institute, Toronto, CANADA), Jeff<br />
Sharom, Brett Larsen, Zhen-Yuan Lin, Lorrie Boucher, Anne-Claude Gingras, Mike Tyers<br />
Cystein Modification In Response To Photoinduced Oxidative Stress In<br />
Saccharomyces Cerevisiae<br />
Audrey Combes (Institut Jacques Monod, FRANCE), Jean Michel Camadro<br />
Changing Profiles Of Mannose-1-Phosphate Guanyltransferase (Psa1) Interacting<br />
Proteins During Batch Culture<br />
Ville Parviainen (Haartman Institute, FINLAND), Sakari Joenväärä, Pirkko Mattila,<br />
Risto Renkonen<br />
Analysis Of Basal And Activated Pre-Initiation Complexes With Itraq Based<br />
Proteomics<br />
Timothy Sikorski (Harvard Medical School, UNITED STATES), Scott Ficarro, Jignesh<br />
Parikh, Manor Askenazi, Stephen Buratowski, Jarrod Marto<br />
A Modular Network Regulates Longevity In Yeast<br />
Vladimir Titorenko (Concordia University, Biology Department, CANADA)<br />
Differential Expression Proteomics Of A Yeast Mutant With Low 14-3-3 Protein<br />
Activity.<br />
Paul van Heusden (Institute of Biology, Leiden University, THE NETHERLANDS)<br />
126 127
Poster Listing<br />
Wednesday 20 august<br />
Array Based Proteomics<br />
P-WED-001<br />
P-WED-002<br />
P-WED-003<br />
The Proteomic Landscape Of In Vitro Growth: A Comparative Analysis Using<br />
Antibody-Based Proteomics<br />
Sara Strömberg, Anna Asplund (Uppsala University, SWEDEN), Linn Fagerberg, Adila<br />
Elobeid, Marcus Gry, Kenneth Nilsson, Peter Nilsson, Rebecca Rimini, Mathias Uhlen,<br />
Fredrik Ponten<br />
Hyphenation Of Surface Plasmon Resonance Imaging To MALDI Mass<br />
Spectrometry By On-Chip MALDI MS Analysis<br />
Sophie Bellon (Genoptics, Orsay France, FRANCE), William Buchmann, Florence<br />
Gonnet, Nathalie Jarroux, Marielle Anger-Leroy, Regis Daniel<br />
Antibody Microarray Scan Of 725 Antibodies To Identify Biomarkers Of<br />
Radioresistance<br />
Laura Smith, Omar Qutob, Mark Watson, Andrew Beavis, Michael Lind, Philip Drew,<br />
Lynn Cawkwell (University of Hull, UNITED KINGDOM)<br />
P-WED-012<br />
P-WED-013<br />
P-WED-014<br />
P-WED-015<br />
Anti-Angiogenic Effect Of A Cell Permeable Peptide, P11, On Huvec<br />
Proliferation Via Analysis Of Differential Protein Expression Profiling Using<br />
ProteoChip-Based Antibody Microarray.<br />
In-Cheol Kang (Department of Biological Science, Biochip Research Center, Hoseo<br />
University, KOREA)<br />
Development Of Screening Method Of Breast Cancer Based On Multiple Serum<br />
Proteins Using Diagnostic Algorithm<br />
Byoung-Kwon Kim (Department of Pathology, Seoul National University Hospital,<br />
KOREA), Chul Woo Kim, Dong-Young Noh, Jong Won Lee, Pil Je Park<br />
Protein Microarrays As Tool For The Quantitative Analysis Of Signal<br />
Transduction In Tumor Samples<br />
Ulrike Korf (Molecular Genome Analysis, German Cancer Research Center,<br />
GERMANY), Christian Löbke, Frauke Henjes, Heiko Mannsperger, Christian Schmidt,<br />
Holger Sültmann<br />
Dub-1, A Fate Determinant Of Dynein Heavy Chain In B-Lymphocytes, Is<br />
Regulated By The Ubiquitin-Proteasome Pathway<br />
Min-Young Lee (Cell and Gene Therapy Research Institute, Graduate School of Life<br />
Science and Biotechnology, Pochon Cha University, Cha General Hospital, KOREA),<br />
Brijesh S. Ajjappala, Myung-Sun Kim, Suresh Ramakrishna, YU-Kyoung Oh, Kwang-<br />
Hyun Baek<br />
P-WED-004<br />
P-WED-005<br />
P-WED-006<br />
P-WED-007<br />
Withdrawn<br />
An Automated Quantitative Platform For The Analysis Of Biomarkers In Tissue<br />
Jason Christiansen (Historx, UNITED STATES), Mark Gustavson, Robert Pinard,<br />
Jane Mayotte, Brian Bourke, Wendy Davis<br />
Cladribine And Fludarabine Induce Proteomic Changes In B-Lymphoproliferative<br />
Disorders<br />
Richard Christopherson (School of Molecular and Micobial Biosciences, University<br />
of Sydney, AUSTRALIA), Swetlana Gez, Carlos Cassano, Stephen Mulligan, Larissa<br />
Belov, Pauline Huang<br />
Multiplexing Immunoassay Platforms: Are They Appropriate For The Biomarker<br />
Discovery Pipeline?<br />
Qin Fu (Johns Hopkins University, Department of Medicine, Bayview Proteomics<br />
Center, UNITED STATES), Jennifer van Eyk<br />
P-WED-016<br />
P-WED-017<br />
P-WED-018<br />
P-WED-0<strong>19</strong><br />
Establishing A High Throughput Platform For Constructing Monoclonal Antibody Bank<br />
Ching-Yu Lin (Graduate Institute of Applied Science and Engineering, Catholic Fu-Jen<br />
University, TAIWAN), Jen-Chieh Lee, Han-Min Chen<br />
Novel Method For Detection Of Activated Transcription Factors In Human<br />
Gestational Tissues<br />
Karen Oliva (Translational Proteomics, Baker Heart Research Institute, AUSTRALIA),<br />
Martha Lappas, Gillian Barker, Greg Rice<br />
MALDI-Ms Readable Protein Arrays<br />
Richard Goodwin, Ekaterina Mckenna, Andrew Pitt (Institute of Biomedical and Life<br />
Sciences, University of Glasgow, UNITED KINGDOM)<br />
Mapping The Human Proteome - A Comprehensive In Situ Analysis Of Protein<br />
Profiles In Normal And Cancer Cells<br />
Fredrik Ponten (Uppsala University, SWEDEN)<br />
P-WED-008<br />
P-WED-009<br />
P-WED-010<br />
P-WED-011<br />
Celluspots Peptide Arrays For Immunodiagnosis And Kinase Profiling<br />
Heinrich Gausepohl (Intavis Bioanalytical Instruments Ag, GERMANY), Evelyn<br />
Rossmann, Ole Brandt, Reinhard Wallich<br />
Large Scale Comperative Rna And Protein Expression Analysis<br />
Marcus Gry (Dept of Proteomics, SWEDEN)<br />
Generation Of Phosphorylation Profiles For Cancer Biomarker Research On<br />
Peptide Microarrays<br />
Riet Hilhorst (Pamgene International Bv, THE NETHERLANDS), Liesbeth Houkes,<br />
Adriënne van Denberg, Rob Ruijtenbeek<br />
Nanobiochips For Proteomics And Diagnostics<br />
Yury Ivanov (Institute of Biomedical Chemistry Rams, RUSSIAN FEDERATION), S<br />
Nikitina, T Pleshakova, A Ivanov, A Kaysheva, P. Frantsuzov, A Archakov<br />
P-WED-020<br />
P-WED-021<br />
P-WED-022<br />
P-WED-023<br />
Multiparametric Protein Analyses From Core Needle Biopsies Of Primary Breast<br />
Cancer Lesions<br />
Thomas Joos, Nicole Schneiderhan-Marra (Nmi Natural and Medical Sciences<br />
Institute at the University of Tubingen, GERMANY), Cornelia Kazmaier, Karin Koretz,<br />
Georg Sauer, Rainer Muche, Helmut Deissler<br />
Profiling Cancer Proteomes With Complex Antibody Microarrays<br />
Christoph Schroeder (German Cancer Research Center, Functional Genome<br />
Analysis, GERMANY), Alexandra Nieters, Sven Rueffer, Jakob Linseisen, Kurt<br />
Fellenberg, Joerg D. Hoheisel<br />
Peptide Microarrays For Immune Monitoring And Biomarker Discovery<br />
Mike Schutkowski (Jpt Peptide Technologies GmbH, GERMANY)<br />
Antibody Suspension Bead Arrays – An Application For Serum And Plasma<br />
Analysis Within Antibody Proteomics<br />
Jochen Schwenk (Department of Proteomics, School of Biotechnology, Kth – Royal<br />
Institute of Technology, SWEDEN), Marcus Gry, Rebecca Rimini, Mathias Uhlén,<br />
Peter Nilsson<br />
128 129
P-WED-024<br />
P-WED-025<br />
P-WED-026<br />
P-WED-027<br />
P-WED-028<br />
Biomarkers Iii<br />
P-WED-029<br />
P-WED-030<br />
P-WED-031<br />
P-WED-032<br />
P-WED-033<br />
P-WED-034<br />
P-WED-035<br />
Profiling Post-Translational Modification Activity In Complex Biological Mixtures<br />
Using Protein Microarray Technology<br />
Charles Spruck (Sidney Kimmel Cancer Center, UNITED STATES), Sonia del Rincon,<br />
Jeff Rogers<br />
An Antibody-Based Proteomics Approach To Identify Diagnostic And Prognostic<br />
Markers In Malignant Melanoma<br />
Sara Stromberg (Dept of Genetics and Pathology, Uppsala University, SWEDEN),<br />
Margret Agnarsdottir, Anna Asplund, Fredrik Ponten<br />
Production Of Hen Egg Yolk Antibodies (Igy) To Human Plasma Proteins<br />
Sock Hwee Tan (Dept of Chemistry and Biomolecular Sciences, Macquarie University,<br />
AUSTRALIA), Amit Kapur, Veronika Polaskova, Wai-Kei Shum, Mark Baker<br />
Tracing Pathway Activities With Kinase Inhibitors And Reverse Phase Protein<br />
Arrays<br />
Jan van Oostrum (Zeptosens, SWITZERLAND), Markus Ehrat, Hans Voshol<br />
Preprocessing And Normalization Of Protein Array Data For Biomarker Discovery<br />
Zhen Zhang (Ctr for Biomarker Discovery, Johns Hopkins School of Medicine, UNITED<br />
STATES), Yan Li, C Nicole Rosenzweig, Lori Sokoll, Xiaer Sun, Katherine Osborne,<br />
Autumn Breaud, Daniel W. Chan<br />
Identification Of Proteomic-Specific Profiles In Patients With Fibrocystic Breast<br />
Disease<br />
Milena Saccomanno (Lab. of Proteomics and Ms, Magna Graecia University of<br />
Catanzaro, ITALY), Domenica Scumaci, Marco Gaspari, Pierosandro Tagliaferri,<br />
Francesco Boccardo, Giovanni Cuda<br />
Tissue Proteomics Of Ovarian Cancer<br />
Michel Salzet (MALDI Imaging Team, FRANCE), Mohamed El Ayed, Amélie -Laure<br />
Jacquet, Pierre Collinet, Jean-Philippe Lucot, Denis Vinatier, Isabelle Fournier<br />
Proteomic Analysis Evidenced Cd148 As A New Biomarker For Mantle Cell<br />
Lymphoma Diagnosis<br />
Laurent Miguet, Luc Fornecker, Raoul Herbrecht, Sarah Sanglier-Cianférani (Cnrs-<br />
Iphc-Dsa-Lsmbo, FRANCE), Alain van Dorsselaer, Laurent Mauvieux<br />
Early Detection Of Oral Precancer Using Protein Biomarkers<br />
Tieneke Schaaij-Visser (University of Utrecht, THE NETHERLANDS), Ruud<br />
Brakenhoff, Albert Heck, René Leemans, Monique Slijper<br />
A Novel Validated Protein Signature For Prostate Cancer Diagnosis<br />
Ralph Schiess (Institute of Molecular Systems Biology / Competence Center for<br />
Systems Physiology and Metabolic Disease, SWITZERLAND), Igor Cima, Silke Gillessen,<br />
Vinzenz Lange, Arnoud Templeton, Thomas Cerny, Wilhelm Krek, Ruedi Aebersold<br />
Urinary Proteomic Biomarkers In Coronary Artery Disease<br />
Eric Schiffer (Mosaiques Diagnostics and Therapeutics Ag, GERMANY), Lukas U.<br />
Zimmerli, Janet K. Snell-Bergeon, David M. Maahs, Harald Harald Mischak, Anna F.<br />
Dominiczak<br />
Analysis Of The Immune System: Whole Blood Stimulation Assays And Multi-<br />
Analyte Profiling<br />
Thomas Joos, Nicole Schneiderhan-Marra, Mike SpaIn, Jim Mapes, Sonja Volk (Nmi<br />
Natural and Medical Sciences Institute at the University of Tubingen, GERMANY),<br />
Marion Schneider, Manfred Schmolz<br />
P-WED-036<br />
P-WED-037<br />
P-WED-038<br />
P-WED-039<br />
P-WED-040<br />
P-WED-041<br />
P-WED-042<br />
P-WED-043<br />
P-WED-044<br />
P-WED-045<br />
P-WED-046<br />
P-WED-047<br />
Identification Of Differentially Expressed Proteins In Breast Cancer Subtypes By<br />
Dige And MALDI-TOFms<br />
Daniela Schulz (Institute of Pathology, Helmholtz Zentrum München, German<br />
Research Center for Environmental Health, GERMANY), Claudia Böllner, Ulrike Reich,<br />
Gerry Thomas, Heinz Höfler, Michaela Aubele<br />
Annexin A3 In Urine: A Novel Biomarker For Prostate Cancer Superior To Psa<br />
Gerhard Schwall (Proteosys Ag, GERMANY), Slobodan Poznanovic, Karlfried Groebe,<br />
Martin Schostak, Markus Müller, Helmut Klocker, Joerg Hennenlotter, Susan<br />
Feyerabend, Arnulf Stenzel, Andre Schrattenholz<br />
Comparative Analysis Of Intestinal Epithelial Cells’ Secretome And Exosomes<br />
Irmgard Schwarte-Waldhoff (University of Bochum, Med. Clinic, Imbl, GERMANY),<br />
Susanne Klein-Scory, Hanna Diehl, Christian Stephan, Katja Kuhlmann, Andrea<br />
Tannapfel, Kai Stühler, Helmut MeYer, Wolff Schmiegel, Bettina Warscheid<br />
Transcriptomic And Proteomic Analysis Of Liver Cancer In Hbx Tg Mice<br />
Je Kyung Seong (Seoul National University, KOREA), Yu Hee Lee, Sae Jin Oh, Kyung<br />
Jin Roh, Dae Yul Yu<br />
New Protein Biomarkers That Distinguish Between Aggressive And Indolent<br />
Chronic Lymphocytic Leukemia<br />
Zhouxin Shen (Cell and Developmental Biology, University of California, UNITED<br />
STATES), Han-Yu Chuang, Laura Z. Rassenti, Thomas J. Kipps, Steven P. Briggs<br />
Maximizing Technical Reproducibility By Multi-Instrument Alignment Allows<br />
In-Depth And Timely Proteomic Analysis Of Large Cohort Of Clinical Samples:<br />
Kidney Function<br />
Simon Sheng (Johns Hopkins University, UNITED STATES), Andrew Meng, Helena<br />
Skalnikova, Qin Fu, Jie Zhu, Jennifer van Eyk<br />
MALDI-TOF Ms Is Perspective Method For Profiling Biomarkers Bound To<br />
Albumine To Detection Lung Cancer<br />
Valeriy Shevchenko (N.N. Blokhin Russian Cancer Research Center, RUSSIAN<br />
FEDERATION), Natalia Arnotskaya, David Zaridze<br />
Quantitative Proteomics Study Of Breast Cancer Cell Lines Isolated From A<br />
Single Patient<br />
Qian Shi (Fudan University, CHINA), Bo Gu, Xiaoen Xu, Meng Qiao, Ping Wei, Yinghua<br />
Jiang, Jing Lu<br />
Targeted Proteomics Of Rat Liver Preneoplastic Lesions Using Laser Capture<br />
Microdissection Coupled With iTRAQ® Reagents<br />
Takeshi Shibata (Applied Biosystems Japan Ltd, JAPAN), Anna Kakehashi, Masayo<br />
Inoue, Masato Aoshima, Mayumi Shindo, Kenichi Kudo, Takuichi Tsubata, Sumie Ando,<br />
Hideki Wanibuchi<br />
Study Of Lysozyme / Lipocalin Ion Ratio In Tear With Age By MALDI-TOF<br />
Jentaie Shiea, Li-Hua Lo (National Sun Yat-Sen University, TAIWAN)<br />
Rapidly Screening Of Albuminuria Using Matrix-Assisted Laser Desorption<br />
Ionization/Time-Of-Flight Mass Spectrometry<br />
Jentaie Shiea, Huan-Yao Wang (Department of Chemistry, National Sun Yat-Sen<br />
University, TAIWAN), Yi-Tzu Cho, Li-Hua Lo, Deng-Chyang Wu, Min-Zong Huang<br />
Rapid Diagnosis Of Hematuria And Hemoglobinuria Using Matrix-Assisted Laser<br />
Desorption Ionization/Time-Of-Flight Mass Spectrometry<br />
Jentaie Shiea, Yi-Hsuan Chen (National Sun Yat-Sen University, TAIWAN), Li-Hua Lo,<br />
Deng-Chyang Wu, Min-Zong Huang<br />
130 131
P-WED-048<br />
P-WED-049<br />
P-WED-050<br />
P-WED-051<br />
P-WED-052<br />
P-WED-053<br />
P-WED-054<br />
P-WED-055<br />
P-WED-056<br />
P-WED-057<br />
Rapid Detection Of Hemoglobins As Ischemic Stroke Biomarkers In Serum By<br />
Mass Spectrometry<br />
Jentaie Shiea, Poyin Huang (Department of Neurology, Kaohsiung Medical University<br />
Chung-Ho Memorial Hospital, Kaohsiung Medical Univ., TAIWAN), Li-Hua Lo, Ching-<br />
Kuan Liu, Yi-Hsuan Chen<br />
Development Of Novel Biomarkers For Breast Cancer In North Indian Population<br />
Yogeshwer Shukla (Indian Institute of Toxicolgy Research, Lucknow, INDIA), Jasmine<br />
George, Preeti Roy, Pranav Chaturvedi, Shailendra Kumar, Sandeep Kumar<br />
Cyclic Abundant Plasma Immuno-Depletion (Capi)<br />
Wai-Kei Shum (Dept of Chemistry and Biomolecular Sciences, Macquarie University,<br />
AUSTRALIA), Amit Kapur, Veronika Polaskova, Sock-Hwee Tan, Mark Baker<br />
Novel Urinary Peptidomic Analysis For Acute Rejection Monitoring For Renal<br />
Transplants<br />
Tara Sigdel (Stanford University Medical School, UNITED STATES), Xuefeng Ling, Ken<br />
Lau, Irwin Lau, James Schilling, Minnie Sarwal<br />
Seppro® Fractionation Platform For Enhanced Detection Of Biomarkers In<br />
Biofluids.<br />
Sergey Sikora (Genway Biotech, Inc., UNITED STATES), Xiangming Fang, Li Deng,<br />
Matthew Landry, Wei-Wei Zhang<br />
Withdrawn<br />
Proteome Characterization Of Healthy And Asthmatic Nasal Epithelium Cells<br />
Tania Simoes (Insa, I.P., PORTUGAL), Fatima Vaz, Antonio Bugalho Almeida, Timothy<br />
Veenstra, Josip Blonder, Deborah Penque<br />
Markers For Assault - Proteomics And Forensic Science In New Zealand<br />
Joanne Simons (Forensic Biology Group, Esr (Institute of Environmental and<br />
Scientific Research), NEW ZEALAND), Sue Vintiner, Penny Truman, Danny Kay, Kelly<br />
Atkinson<br />
Prognostic Significance Of Head-And-Neck Cancer Biomarkers Previously<br />
Discovered And Identified Using iTRAQ-Labeling And Multidimensional Liquid<br />
Chromatography – Tandem Mass Spectrometry<br />
KW Michael Siu (York University, CANADA), Ajay Matta, Nootan Kumar Shukla,<br />
Siddhartha D. Gupta, Ranju Ralhan<br />
Stabilization Of Proteins And Peptides And Identification Of Peptides In<br />
Pancreatic Tissue<br />
Karl Sköld (Denator Ab, SWEDEN), Céline Fernandez, Sofia Waldemarson, Roberto<br />
Stella, Mikhail Savitski, Marcus Svensson, Mats Borén, Roman Zubarev, Per E.<br />
Andrén, Peter James<br />
P-WED-061<br />
P-WED-062<br />
P-WED-063<br />
P-WED-064<br />
P-WED-065<br />
P-WED-066<br />
P-WED-067<br />
P-WED-068<br />
P-WED-069<br />
P-WED-070<br />
Withdrawn<br />
Multiple Sclerosis Related Proteins In Csf Identified By Advanced Mass Spectrometry<br />
Marcel Stoop (Department of Neurology, Erasmus University Medical Centre, THE<br />
NETHERLANDS), Lennard Dekker, Mark Titulaer, Peter Burgers, Peter Sillevis<br />
Smitt, Theo Luider, Rogier Hintzen<br />
Sample Preparation For Molecular Histology<br />
Martin Schürenberg (Bruker Daltonics, GERMANY), Gongyi Shi, Rolf Müller, Sören O.<br />
Deininger, Detlev Suckau<br />
Effect Of 50-Hz Magnetic Fields On Proteome Of Human Sh-Sy5y<br />
Neuroblastoma Cells<br />
Marilisa Sulpizio (Department of Biomedical Science, Excellent Center on Aging<br />
Studies, ITALY), Stefano Falone, Enrica Eleutero, Fabrizio di Giuseppe, Alessandro<br />
Mirabilio, Fernanda Amicarelli, Carmine di Ilio, Stefania Angelucci<br />
A Dynamic Urinary Proteomic Analysis Reveals Stable Proteins May Be Used As<br />
A Source Of Potential Biomarker<br />
Wei Sun (Department of Pathophysiology, Proteomics Research Center, Institute<br />
of Basic Medical Sciences, Chinese Academy of Medical Sciences / Peking Union<br />
Medical College, CHINA)<br />
Serum Amyloid A As A Serum Biomarker For The Detection Of Lung Adenocarcinoma<br />
Hye-Jin Sung (Department of Biochemistry, School of Dentistry Kyungpook National<br />
Univ., KOREA), Jung-Mo Ahn, Jae-Young KIm, Jae-Yong Park, Je-Yoel Cho<br />
A Novel Approach For Biomarker Discovery In Colorectal Cancer<br />
Silvia Surinova (Institute of Molecular Systems Biology / Life Science Zürich Phd<br />
Program ‘Systems Biology of Complex Diseases’ of The Competence Center for<br />
Systems Physiology and Metabolic Disease, SWITZERLAND), Bruno Domon, Marian<br />
Hajdúch, Ruedi Aebersold<br />
Peptidomic Analysis Of Serum And Dialysate In Hemodialysis Patients<br />
Kenji Tanaka (Protosera, Inc., JAPAN), Lyang-Ja Lee, Yoshihiro Motomiya, Ikurou<br />
Maruyama<br />
Csf Proteomics To Identify Candidate Biomarkers For Multiple Sclerosis<br />
Charlotte Teunissen (Vu University Medical Center Amsterdam, Department of<br />
Molecular and Cellular Biology and Immunology, THE NETHERLANDS), Marleen Koel-<br />
Simmelink, Thang Pham, Laura van der Voort, Connie Jimenez<br />
Als Biomarker Discovery In Cortex Samples By MALDI-TOF, MALDI Imaging, And<br />
MALDI-Ftms<br />
Kristin Boggio, Long Li, Michael L. Easterling, Christopher J. Thompson (Bruker<br />
Daltonics Inc., UNITED STATES), Nathalie Y.R. Agar, Jeffrey N. Agar<br />
P-WED-058<br />
P-WED-059<br />
P-WED-060<br />
Global Shotgun Proteomic Analysis Of Colorectal Carcinoma<br />
Robbert Slebos (Vanderbilt University, UNITED STATES)<br />
Proteomics Of Sepsis<br />
Afonso Soares (Protein Chemistry Laboratory, Dept of Biochemistry, Institute of<br />
Chemistry, Ufrj/ Rio de Janeiro Proteomics Network, BRAZIL), Marise Santos,<br />
Monique Trugilho, Ana Ferreira, Jonas Perales, Gilberto Domont<br />
Proteomic Analyses Of Retina Of Excitatory Amino Acid Carrier 1 (Eaac1)-<br />
Deficient Mice<br />
Nazariy Souchelnytskyi (Karolinska Biomics Center, SWEDEN)<br />
P-WED-071<br />
P-WED-072<br />
P-WED-073<br />
Identification And Quantification Of Tear Proteins In Sjogren’s Syndrome<br />
Naohisa Tomosugi (Kanazawa Medical University, JAPAN), Kazuko Kitagawa, Hideyuki<br />
Tsuchida, Masato Higuchi<br />
Serum Proteome Analysis Of Patients With Hodgkin’s Lymphoma<br />
Thanh Tran (Institute of Biotechnology (Ibt), Vietnam), Chi Phan<br />
Prognostic Biomarker In Esophageal Cancer By 2d-Dige, Tumor Tissues And<br />
Clinical Data<br />
Norihisa Uemura (Proteome Bioinformatics Project, National Cancer Center Research<br />
Institute / Division of Esophageal Surgery, National Cancer Center Hospital / Division<br />
of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine,<br />
JAPAN), Yukihiro Nakanishi, Hoichi Kato, Masato Nagino, Setsuo Hirohashi, Tadashi Kondo<br />
132 133
P-WED-074<br />
Identification Of A Tamoxifen Response Protein Profile In Breast Cancer By<br />
Nanolc-Fticr Ms<br />
Arzu Umar (Erasmus Mc Rotterdam, THE NETHERLANDS)<br />
P-WED-087<br />
Measuring Protein Synthesis As Part Of Proteomics Study On Cancer Cell Proliferation<br />
Gary Guishan Xiao (Genomics & Functional Proteomics Lab/Orc at Creighton University,<br />
UNITED STATES), Yingchun Zhao, Shu Lim, Jing Xiao, Robert Recker, Wai-Nang Paul Lee<br />
P-WED-075<br />
P-WED-076<br />
P-WED-077<br />
P-WED-078<br />
Addressing Systematic Factors Affecting Ms Molecular Biomarker Discovery<br />
Andrea Urbani (University of Chieti and Pescara / Irccs-Santa Lucia, ITALY),<br />
Damiana Pieragostino, Piero del Boccio, Francesca Petrucci, Dante Mantini, Barbara<br />
Pavone, Valeria Marzano, Federica Forli, Carmine di Ilio, Giorgio Federici<br />
Sarcoidosis Specific Biomarkers Detection In Bronchoalveolar Lavage 2d<br />
Proteomes For The Early Diagnosis Of The Disease<br />
María Uribarri (Proteomika S.L., SPAIN), Hannelore Kothmaier, Susanna Petzmann,<br />
Alberto Monasterio, José Riera, Daniel Nagore, Laureano Simón, Antonio Martinez,<br />
Helmut Popper<br />
Identification Of Carboxymethyl Lysine Modified Serum Proteins From Diabetic Patients<br />
Meeme Utt (University of Tartu, ESTONIA)<br />
Segment-Specific Analysis And Quantitation Of The Mouse Nephron Proteome<br />
Ana Velic (Max-Planck Institute of Biochemistry, GERMANY), Boris Macek, Jürgen<br />
Cox, Florian Gnad, Maria Lecca, Andre Brändli, Johannes Loffing, Nicolas Picard,<br />
Carsten Wagner, Matthias Mann<br />
P-WED-088<br />
P-WED-089<br />
P-WED-090<br />
P-WED-091<br />
Identificating Nm23-H1 As A Metastasis-Promoting Factor In Nasopharyngeal<br />
Carcinoma By Proteomic Analysis<br />
Zhi-Qiang Xiao (Key Laboratory of Cancer Proteomics of Chinese Ministry of Health,<br />
Xiangya Hospital, Central South University, CHINA), Bin Yi, Mao-Yu Li, Peng-Fei<br />
Zhang, Cui Li, Zhu-Chu Chen<br />
Identificating Cathepsin D As A Biomarker For Differentiation And Prognosis Of<br />
Nasopharyngeal Carcinoma By Laser Capture Microdissection And Proteomic<br />
Analysis<br />
Bin Yi (Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya<br />
Hospi, CHINA), Ai-Lan Cheng, Wei-Guo Huang, Zhu-Chu Chen, Zhi-Qiang Xiao<br />
Changes In Levels Of Prostaglandin D2 Metabolite In Cerebrospinal Fluids Of<br />
Rheumatoid Patients<br />
Yukio Yamamoto (Tokyo Metropolitan Institute of Medical Science, JAPAN), Mariko<br />
Shimamura, Yoshiko Akiota, Hiroshi Sato, Susumu Fukasaku, Kosuke Aritake<br />
Withdrawn<br />
P-WED-079<br />
Identification Of Biomarkers For Depression-Like Behavior In A Mouse Model<br />
Christian Webhofer (Max Planck Institute of Psychiatry, GERMANY), Yuji Odagaki,<br />
Birgit Bisle, Elisabeth Frank, Melanie Keßler, Katrin Haegler, Giuseppina Maccarrone,<br />
Boris Hambsch, Rainer Landgraf, Christoph W. Turck<br />
P-WED-092<br />
Cross-Link Of Proteome With Transcriptome For Metastasis Hcc<br />
Pengyuan Yang (Institutes for Biomedical Sciences and Research Institute For Liver<br />
Cancer, Fudan University, CHINA), Huali Shen, Fan Zhong, Yang Zhang, Yinkun Liu,<br />
Fuchu He<br />
P-WED-080<br />
P-WED-081<br />
P-WED-082<br />
Quantitative Proteomic Analysis Of Hsp90 Modulation Using iTRAQ-Based<br />
Online Three-Dimensional Nlc-Esi-Cid-Pqd-Ms/Ms<br />
Jing Wei (Biogen Idec Corp., UNITED STATES), Ben Colson, Mark J. Daniels, Diem<br />
Tran, Noel Timple, Naveen Dakappagari, Shabnam Tangri, Steve French, Karen<br />
Lundgren, Alex Buko<br />
Comparative Proteomic Biomarkers Analysis Of Human Brain Tumors<br />
Ching-Yi Weng (Institute of Basic Medical Science, College of Medicine, National<br />
Cheng-Kung University, TAIWAN), Kuo-Chen We, Tsuey-Yu Chang, Chia-Haw Huang,<br />
Jung-Hsien Chiang, Petrus Tang, Jyh-Wei Shin<br />
Diagnosis Of Ovarian Cancer By Mass Spectrometry – Getting Closer?<br />
Mikkel West-Nørager (Statens Serum Institut, DENMARK), Rasmus Bro, Estrid<br />
Høgdall, Claus Høgdall, Lotte Nedergaard, Niels H.H. Heegaard<br />
P-WED-093<br />
P-WED-094<br />
P-WED-095<br />
Autoantibody To Tumor Antigen, Alpha 2-Hs Glycoprotein: A Novel Biomarker Of<br />
Breast Cancer<br />
Jae Kyo Yi (Cancer Institute, Seoul National University College of Medicine, KOREA),<br />
Jong Wook Chang, Wonshik Han, Jong Won Lee, Myeong-Hee Yu, Dong-Young Noh<br />
Comprehensive Analysis Of Cell-Cycle-Associated Biomarkers Induced By Genistein<br />
Kenichi Yoshida (Meiji University, JAPAN)<br />
Proteomic Profiling Of Human Lymphatic Endothelial Cells For Analyzing<br />
Lymphangiogenesis<br />
Yasunobu Yoshida (Laboratory of Pharmaceutical Proteomics, National Institute of<br />
Biomedical||Innovation (Nibio)/ Graduate School of Pharmaceutical Sciences, Osaka<br />
University, JAPAN), Sunao Imai, Tomoaki Yoshikawa, Haruhiko Kamada, Shin-Ichi<br />
Tsunoda, Yasuo Tsutsumi<br />
P-WED-083<br />
Early Protein Biomarkers Associated With Experimentally Induced Gastric<br />
Cancer In Rats<br />
Lam Wing Kei (The Proteomic Task Force, Department of Applied Biology and<br />
Chemical Technology, The Hong Kong Polytechnic University, CHINA)<br />
P-WED-096<br />
Identification Of The Potential Biomarkers For Prostate Cancer From Tears And Sera<br />
Jingjing You (University of New South Wales / Minomic Pty Ltd, AUSTRALIA), Anna<br />
Fitzgerald, Paul J. Cozzi, Zhenjun Zhao, Pamela J. Russell, Bradley J. Walsh, Mark<br />
Willcox, Yong Li<br />
P-WED-084<br />
P-WED-085<br />
P-WED-086<br />
Serum Protein Profiling Of Sle Using Recombinant Antibody Microarrays<br />
Christer Wingren (Lund University, SWEDEN)<br />
Proteomic Serum Profiling For Analyzing The Individual Risk For Endometriosis<br />
Monika Wölfler (Rwth Aachen University, Department of Obstetrics and Gynecology,<br />
GERMANY), Daniela Otten, Corinna Henkel, Ruth Knüchel-Clarke, Werner Rath,<br />
Kristina Schwamborn<br />
Proteomic And Bioinformatic Analysis Of Cancer-Cell Secretome For Biomarker<br />
Identification<br />
Chih-Ching Wu (Proteomics Core Laboratory / Molecular Medicine Research Center,<br />
Chang Gung University, TAIWAN), Chia-Wei Hsu, Chi-De Chen, Jau-Song Yu<br />
P-WED-097<br />
P-WED-098<br />
P-WED-099<br />
Withdrawn<br />
Biomarker Screening Using Feature Selection And Analysis Framework<br />
Su-Jun Li (Shanghai Institutes for Biological Sciences, CHINA), Rong-Xia Li, Wei-Ping<br />
Jia, Yi-Xue Li, Jia-Rui Wu, Rong Zeng<br />
Proteome Analysis Of Mouse Lung Cancer Cmt Cell Lines<br />
Kelan Zhang (Protein Research Group, Dept. of Biochemistry and Molecular Biology,<br />
University of Southern Denmark, DENMARK), Krzysztof Wrzesinski, Stephen J. Fey,<br />
Peter Mose Larsen, Xumin Zhang, Peter Roepstorff<br />
134 135
P-WED-100<br />
P-WED-101<br />
Biomarker Discovery In Brain And Plasma Of A Mouse Model Of Trait Anxiety<br />
Y Zhang (Max Planck Institute f Psychiatry, GERMANY), Md Filiou, B Bisle, E Frank,<br />
Ms Ksssler, K Haegler, G Maccarrone, B Hambsch, R Landgraf, Cw Turck<br />
Exploring Biomarkers From Pancreatic Cancer Secretome<br />
Xiaohang Zhao (State Key Laboratory of Molecular Oncology, Cancer Institute &<br />
Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, CHINA)<br />
Cardiovascular Proteome Biology<br />
P-WED-102<br />
P-WED-103<br />
P-WED-104<br />
P-WED-105<br />
P-WED-106<br />
P-WED-107<br />
P-WED-108<br />
P-WED-109<br />
P-WED-110<br />
P-WED-111<br />
The Effect Of 7,8-Dihydroxy-3-(3-Methylphenyl) Coumarin On The Protein<br />
Profiles Of Rat Liver<br />
Volkan Altay (Marmara University Faculty of Arts and Sciences, Turkey), Basak<br />
Yuce, Ayse Ogan, Goksel Sener, Mustafa Bulut<br />
Secretome Analysis Of Human Artery Biopsies In The Search For<br />
Atherothrombotic Biomarkers<br />
Gloria Alvarez-Llamas, Fernando de la Cuesta, Veronica M. Darde, Maite Tejerina,<br />
Rocio Juarez, Luis R. Padial, Angel G. Pinto, Maria G. Barderas, Fernando Vivanco<br />
(Department of Immunology. Fundacion Jimenez Diaz / Department of Biochemistry<br />
and Molecular Biology, Universidad Complutense, SPAIN)<br />
New Insights Into The Pathogenesis Of Ectopic Calcification: A Lesson From The<br />
Pxe Model<br />
Giulia Annovi (University of Modena and Reggio Emilia, ITALY), Federica Boraldi, Leon<br />
J Schurgers, Cees Vermeer, Ivonne Pasquali-Ronchetti, Daniela Quaglino<br />
Myocardial Proteomic Profiling Helps Identify Different Forms Of Heart Disease<br />
Gökhan Baykut (Bruker Daltonik GmbH, GERMANY), Matthias Witt, Maria Bergquist,<br />
Hans-Reinhard Zerkowski, Doan Baykut, Jonas Bergquist<br />
Lipolytic Activity Profiling In Mouse Liver<br />
Ruth Birner-Gruenberger (Medical University of Graz, AUSTRIA), Albin Hermetter,<br />
Manfred Kollroser, Heidrun Susani-Etzerodt, Gerald Rechberger<br />
Characterization Of The Murine Cardiac Proteome<br />
Nicolas Bousette (Department of Physiology, University of Toronto, CANADA),<br />
Thomas Kislinger, Ruth Isserlin, Andrew Emili, Anthony Gramolini<br />
Changes In The Rat Aorta Proteome With The Dietary Folate Supply<br />
Patrick Brachet (Institut National de la Recherche Agronomique, FRANCE)<br />
Proteomic Analysis Of A Mouse Model Of Heart Failure Resulting From Cardiac<br />
Hypertrophy<br />
Shaan Chugh (Banting and Best Department of Medical Research, University of<br />
Toronto, CANADA)<br />
Isolation Of Human Arterial Intimal Layer And Single Cells For Proteomic<br />
Analysis<br />
Fernando de la Cuesta (Fundacion Jimenez Diaz-Capio, SPAIN), Gloria Alvarez-<br />
Llamas, Veronica M. Darde, Alicia Donado, Aroa S. Maroto, Luis R. Padial, Angel G.<br />
Pinto, Maria G. Barderas, Fernando Vivanco<br />
Electron Transfer Dissociation (Etd) Enabled Identification Of Specific<br />
Phosphorylation Sites In Key Metabolic Enzymes Of Cardiac Mitochondria<br />
Philip Doran (Ucla, UNITED STATES), Yueju Wang, Ning Deng, Jun Zhang, Chenggong<br />
Zong, Michael Mueller, Paavo Korge, James Weiss, Rolf Apweiler, Peipei Ping<br />
P-WED-112<br />
P-WED-113<br />
P-WED-114<br />
P-WED-115<br />
P-WED-116<br />
P-WED-117<br />
P-WED-118<br />
P-WED-1<strong>19</strong><br />
P-WED-120<br />
P-WED-121<br />
P-WED-122<br />
P-WED-123<br />
Analysis Of Proteins Secreted During Vessel Maturation In An In-Vitro<br />
Angiogenesis Model<br />
Tom Dunkley (Astrazeneca, UNITED KINGDOM), Mark Pearson, Rachel Rowlinson,<br />
Beverley Isherwood, Simon Barry<br />
Proteomic Analysis Of Cardiac Targets Involved In Anesthetic-Induced Preconditioning<br />
Nadine Dyballa (University of Duesseldorf, GERMANY), Christian Schuh, Hendrik<br />
Vogt, Wolfgang Schlack, Nina Weber, Sabine Metzger<br />
Lipid Rafts In Platelets - Novel Signalling Platforms?<br />
Beate Eyrich (Protein Mass Spectrometry and Functional Proteomics Group, Rudolf-<br />
Virchow-Center for Experimental Biomedicine, GERMANY), Albert Sickmann<br />
Characterization Of The Human Platelet Proteome By Shotgun Lc-Ms/Ms Analysis<br />
Marco Gaspari (Dept. Experimental & Clinical Medicine, University of Catanzaro,<br />
ITALY), Shibu Krishnan, Cosimo Gasparri, Giuseppe Argirò, Patrizia Bianchi, Annalisa<br />
Fregola, Daniele Torella, Ciro Indolfi, Giovanni Cuda<br />
Dynamic Cardiac Mitochondrial Proteome Alterations After Ischemia/Reperfusion<br />
Injury<br />
Abdelbary Prince (Department of Physiology and Biophysics, Mitochondrial Signaling<br />
Laboratory, College of Medicine, Cardiovascular and Metabolic Diseases Center, Inje<br />
University, Korea / Department of Biochemistry, Faculty of Veterinary Medicine,<br />
Cairo University, Egypt), Hyungkyu Kim, Samy Abdelaziz, Eman Gouda, Jin Han<br />
Withdrawn<br />
Effects Of Dilated Cardiomyopathy And Immunoadsorption Therapy On Cardiac<br />
Gene Expression<br />
Sabine Ciecholewski (Medical Faculty, University Greifswald, GERMANY), Katrin<br />
Darm, Leif Steil, Alexander Staudt, Elke Hammer, Sacha Aft van Hijum, Heyo K<br />
Kroemer, Reinhardt Kandolf, Stephan B Felix, Uwe Völker<br />
Bh4 Deficiency Impaired Cardiac Mitochondrial Function<br />
Hyoung Kyu Kim (Department of Physiology, Colleage of Medicine, Inje University,<br />
KOREA), Won Sun Park, Abdel Bary Prince, Jin Han<br />
Analysis Of Protein Profiles In Astemizole And Loratadine-Treated Rat<br />
Cardiomyocytes<br />
So Young Kim (Korea Food & Drug Administration, KOREA), Ho-Sang Jeong Ho-Sang<br />
Jeong, Moon Jeong Ko Moon Jeong Ko, Joon Ik Ahn Joon Ik Ahn, Sun Ok Choi, Hye<br />
Joo Chung Hye Joo Chung<br />
Human Plasma Proteome Investigations Into Acute Coronary Microvascular<br />
Disorders<br />
Victoria Kopetz (The Queen Elizabeth Hospital, AUSTRALIA), Megan Penno, Peter<br />
Hoffmann, John Beltrame<br />
iTRAQ Analysis Of Doxorubicin Effect On Rat Heart Myoblast-Derived Cells H9c2<br />
Juraj Lenco (Department of Molecular Pathology, Faculty of Military Health<br />
Sciences, University of Defence, CZECH REPUBLIC), Marek Link, Tomas Simunek,<br />
Martin Sterba, Jiri Stulik<br />
Analysis Of The Platelet Proteome<br />
Urs Lewandrowski (Rudolf-Virchow-Center for Experimental Biomedicine, Protein<br />
Mass Spectrometry and Functional Proteomics Group, University Würzburg,<br />
GERMANY), Rene Zahedi, Katharina Lohrig, Dirk Wolters, Stefanie Wortelkamp,<br />
Thomas Premsler, Albert Sickmann<br />
136 137
P-WED-124<br />
P-WED-125<br />
P-WED-126<br />
P-WED-127<br />
P-WED-128<br />
Participate In The Cardiovascular Gene Ontology Annotation Initiative<br />
Ruth Lovering (Centre for Cardiovascular Genetics, Department of Medicine,<br />
University College London, UNITED KINGDOM), Varsha Khodiyar, Emily Dimmer,<br />
Daniel Barrell, Peter Scambler, Mike Hubank, Rolf Apweiler, Philippa Talmud<br />
Proteomics, Metabolomics And Immunomics On Atherosclerotic Plaques-Derived<br />
Microparticles<br />
Manuel Mayr (Cardiovascular Division, Kings College London, University of London,<br />
UNITED KINGDOM), David Grainger, Ursula Mayr, Aurelie Leroyer, Guy Leseche,<br />
Anissa Sidibe, Xiaoke Yin, Basseti Madhu, Aldrin Gomes, John Griffiths<br />
Phenotyptic Continuum Between Growth And Protection: Analysis Of Organellar<br />
Sub-Proteomes In The Heart<br />
Anna Paulsson (University of California, UNITED STATES), Sarah Warburton, Shuxun<br />
Ren, Sherise Mitchell, Sujing Wang, Yibin Wang, Thomas Vondriska<br />
Proteomics Characterization Of Hemodialysis Membranes Biocompatibility<br />
Luisa Pieroni (Fondazione S. Lucia - Irccs, ITALY), Andrea Urbani, Mario Bonomini,<br />
Santina Lupisella, Barbara Pavone, Sonia Bucci, Vittorio Sirolli, Moreno di Cesare,<br />
Giorgio Federici, Federica Forli<br />
Role Of Endothelial Cells As Targets Of Low-Dose Radiation In Cardiovascular<br />
Diseases<br />
Franka Pluder (Institute of Radiation Biology, Helmholtz Zentrum München – German<br />
Research Center for Environmental Health (GmbH), GERMANY), Reetta Nylund,<br />
Dariusz Leszczynski, Michael Atkinson, Soile Tapio<br />
P-WED-136<br />
P-WED-137<br />
P-WED-138<br />
P-WED-139<br />
P-WED-140<br />
P-WED-141<br />
Investigating Post-Translational Modifications Of Apo B-100 By Oxidative Stress<br />
Katrina Thomson (Glasgow University, UNITED KINGDOM), Edina Silajdzic, Laetitia<br />
Mouls, Corinne Spickett, Andrew Pitt<br />
Mass Spectrometry-Based Analysis Of Nitroxylated Proteins In The Human<br />
Platelet Proteome<br />
Geraldine Walsh (Biomedical Research Centre, CANADA), Michael Hoffman, Dana<br />
Devine, Juergen Kast<br />
Proteomic Analysis Of Failed Thrombolysis Following Acute Myocardial Infarction<br />
Jules Westbrook (Ucd Conway Institute of Biomolecular and Biomedical Research,<br />
University College Dublin, Ireland)<br />
Alterations To The Mitochondrial Subproteome With Myocardial Ischemic<br />
Preconditioning<br />
Melanie Y. White (Johns Hopkins School of Medicine, UNITED STATES), David A.<br />
Brown, Brian O’Rourke, Jennifer E. van Eyk<br />
The Secretome Of Colony Forming Units And Non-Colony Forming Endothelial<br />
Progenitor Cells<br />
Xiaoke Yin (Cardiovascular Division, King’s College London, UNITED KINGDOM),<br />
Ursula Mayr, Colin Evans, Qingzhong Xiao, Qingbo Xu, Manuel Mayr<br />
A Proteomics Study Of Mouse Brain Endothelial Cells After Oxygen And Glucose<br />
Deprivation<br />
Chenggang Zhang (Beijing Institute of Radiation Medicine, CHINA), Yong Gu<br />
P-WED-129<br />
Proteomics Analysis Of Role Of Hsp60 In Digitalis-Induced Toxicity In Endothelial<br />
Cells<br />
Jie Qiu (Shandong University Qilu Hospital, CHINA), Hai-Qing Gao, Xiao-Pei Cui, Gai-<br />
Xia Zhao<br />
P-WED-142<br />
Tec Tyrosine Kinase Signaling In Cardiac Ischemia And Reperfusion<br />
Michael Zhang (Departments of Anesthesiology, Medicine and Physiology, University<br />
of California, UNITED STATES), Sarah Warburton, Sujing Wang, Scherise Mitchell,<br />
Hiroyuki Mano, Thomas Vondriska<br />
P-WED-130<br />
P-WED-131<br />
Label-Free Quantitative Protein Study Of Plasma In Patients With Coronary<br />
Artery Disease<br />
Susanne Ragg (Indiana University School of Medicine, UNITED STATES), Olga Vitek,<br />
Gunther Schadow, Vladimir Fokin, Nadine Lee, Siegmund Braun, Ilka Ott<br />
Human Primary Subcutaneous Adipocytes Are Source Of Many Cytokines And<br />
Chemokines<br />
Marcel de Vries, Marcel van Bruinenberg, Saed Lahham, Desiree Weening, Andrea<br />
Venema, Niels Kloosterhuis, Roel Vonk, Farhad Rezaee (University Medical Centre<br />
Groningen, THE NETHERLANDS)<br />
P-WED-143<br />
Activation Of Aortic Endothelial Cells By Oxidized Phospholipids:<br />
Phosphoproteomic Analysis<br />
Alejandro Zimman (Pathology & Laboratory Medicine, University of California,<br />
UNITED STATES), Sharon S. Chen, Evangelia Komisopoulou, Wan Lam Szeto, Judith<br />
A. Berliner, Thomas G. Graeber<br />
P-WED-132<br />
Mlc Degradation Is Associated With Increased Mmp-2 Activity In Neonatal<br />
Pigs With Hypoxia-Reoxygenation<br />
Jolanta Sawicka, Justyna Fert-Bober, Po-Yin Cheung, Grzegorz Sawicki (University<br />
of Saskatchewan, CANADA)<br />
P-WED-133<br />
Purification Of Endogenous Cardiac Thick Filament Proteins For Ptm<br />
Identification<br />
Sarah B. Scruggs (University of Illinois at Chicago, Center for Cardiovascular<br />
Research, UNITED STATES), Peter M. Buttrick, R John Solaro<br />
P-WED-134<br />
Proteomic Profiling Of The Cardiomyocyte Plasma Membrane<br />
Parveen Sharma (Department of Physiology, University of Toronto, CANADA), Alex<br />
Ignatchenko, Nic Bousette, Andreas Evangelou, Anthony Gramolini, Thomas Kislinger<br />
P-WED-135<br />
Four And A Half Lim Domains Protein 1 (Fhl1) Interactions In Mammalian Muscle<br />
Thiruchelvi Shathasivam (Department of Physiology, University of Toronto, CANADA),<br />
Parveen Sharma, Alex Ignatchenko, Thomas Kislinger, Anthony Gramolini<br />
138 139
Integration And Storage Of Proteomics Data<br />
P-WED-144<br />
P-WED-145<br />
P-WED-146<br />
P-WED-147<br />
Prose – “Software As A Service” For Quantitative Proteomics<br />
Stefan Albaum (Center for Biotechnology, Bielefeld University, GERMANY),<br />
Heiko Neuweger, Sita Lange, Dominik Mertens, Kai Runte, Joern Kalinowski, Tim<br />
Nattkemper, Alexander Goesmann<br />
A Common Sequence Database Format In Proteomics<br />
Pierre-Alain Binz (Swiss Institute of Bioinformatics, Proteome Informatics Group<br />
/ Geneva Bioinformatics (Genebio) Sa, SWITZERLAND), Eugene A. Kapp, Jim<br />
Shofstahl, David Creasy, Uniprot Consortium, Jayson A. Falkner, Philip C. Andrews,<br />
Sean L. Seymour<br />
The Human Muscle Proteome In Unloading-Induced Atrophy: data Management<br />
Using Proteus(Tm)Software.<br />
Gary Coulton (St. George’s, University of London, UNITED KINGDOM), Glen Alder,<br />
Maarten de Boer, Marco Narici, Simon Swindell, Kevin Jones<br />
Proteomics Tools And Pipelines Work Packages 3 & 5 Of Prodac (Proteomics<br />
Data Collection)<br />
Martin Eisenacher (Medizinisches Proteom-Center, Ruhr-Universitaet Bochum,<br />
GERMANY), Phil Jones, Lennart Martens, Fredrik Levander, Michael Kohl, Jari<br />
Häkkinen, Rolf Apweiler, Helmut E. Meyer, Christian Stephan<br />
P-WED-155<br />
P-WED-156<br />
P-WED-157<br />
P-WED-158<br />
P-WED-159<br />
The Psi Semantic Validators – How Compliant Is Your Proteomics Data?<br />
Samuel Kerrien (European Molecular Biology Laboratory (Embl) – European<br />
Bioinformatics Institute, Wellcome Trust Genome Campus, UNITED KINGDOM), Luisa<br />
Montecchi-Palazzi, Florian Reisinger, Bruno Aranda, Andrew R. Jones, Matthias<br />
Oesterheld, Lennart Martens, Henning Hermjakob<br />
Proteincv: Hierarchical Statecharts Data Model For Molecular Information On<br />
Proteins<br />
Per Kraulis (Avatar Software Ab, SWEDEN)<br />
Miape Generator Tool: A Useful Aid To Report Proteomics Experiments According<br />
To Miape Guidelines<br />
Salvador Martínez de Bartolomé (Proteored - National Center for Biotechnolgy-<br />
Csic, SPAIN), Alberto Medina, Jose María Carazo, Juan Pablo Albar<br />
A New Web Standard-Based Interface To Report Proteomics Experiments<br />
J Alberto Medina-Aunon (Proteomics Facility, National Center for Biotechnology<br />
(Cnb-Csic), Spanish Proteomics Institute (Proteored), SPAIN), J Pablo Albar<br />
The International Molecular Exchange Consortium<br />
Sandra Orchard (Embl- European Bioinformatics Institute, UNITED KINGDOM),<br />
Samuel Kerrien, Bruno Aranda, Arnaud Coel, Andrew Chatr-Arymontri, Lukasz<br />
Salwinski, Sylvie Ricard Blum, Rolf Apweiler, Henning Hermjakob<br />
P-WED-148<br />
Prodac Proteomics Data Collection - Coordinated Action Within The 6th Eu<br />
Framework Programme<br />
Christian Stephan (Medizinisches Proteom-Center, Ruhr-Universitaet Bochum,<br />
GERMANY), Tanja Hardt, Martin Eisenacher, Michael Hamacher, Rolf Apweiler,<br />
Jari Häkkinen, Rudi Aebersold, Joel Vandekerckhove, Michael J. Dunn, Frederique<br />
Lisacek, Ron Appel, Simon Hubbard, Pierre-Alain Binz, Martin Blüggel, Herbert<br />
Thiele, John Cottrell, Helmut E. Meyer<br />
P-WED-160<br />
P-WED-161<br />
Using Discovery To Power Targeted Analysis: From Traps To Triples<br />
Amol Prakash (Thermofisher Scientific, UNITED STATES), David Sarracino, Michael<br />
Athanas, Bryan Krastins, Scott Peterman, Kypros Nicholaides, Mary Lopez<br />
Generalized Method For Statistical Analysis Of Peptide Identification Scores<br />
From Ms/Ms Data And Database Searching<br />
Antonio Ramos Fernández (Cnb-Csic, SPAIN)<br />
P-WED-149<br />
Epims: A Versatile Tool For Data Management And Analyses Scheduling<br />
Myriam Ferro (Cea, FRANCE), Véronique Dupierris, Mimi Grebici, Damien Barthe,<br />
Jérôme Garin, Christophe Bruley<br />
P-WED-162<br />
Pass: End-To-End Bioinformatics Data Warehouse For Clinical Proteomics<br />
Gautam Saxena (Integrated Analysis, Inc., UNITED STATES), Julius C-Zar, Cathy<br />
Kimani, Edwin Mulwa<br />
P-WED-150<br />
Accelerating Proteomics Through Integrated Data Management And<br />
Bioinformatics Pipelining<br />
Charles G. Howes, Frank Worsley, Matthew J. Myhre, Mike Sanders, Leonard<br />
J. Foster (Centre for High-Throughput Biology, Department of Biochemistry &<br />
Molecular Biology, University of British Columbia, CANADA)<br />
P-WED-163<br />
Managing Proteomics Data From Generation And Data Warehousing To Central<br />
Data Repository<br />
Herbert Thiele (Bruker Daltonik GmbH, GERMANY), Peter Hufnagel, Jörg Glandorf,<br />
Gerhard Körting, Martin Blüggel, Martin Eisenacher, Helmut E. Meyer, Christian<br />
Stephan<br />
P-WED-151<br />
World-2dpage Repository: Your Contribution To A Large Proteomics Data<br />
Network<br />
Christine Hoogland (Swiss Institute of Bioinformatics, SWITZERLAND), Khaled<br />
Mostaguir, Ron D. Appel, Frederique Lisacek<br />
P-WED-164<br />
Data Processing And Analysis At The Biomolecular Mass Spectrometry And<br />
Proteomics Group<br />
Henk W.P. van den Toorn (Uu, THE NETHERLANDS), Madalina Drugan, Robert<br />
Kerkhoven, Albert Heck, Bas van Breukelen<br />
P-WED-152<br />
P-WED-153<br />
Genome Medicine Database Of Japan Proteomics (Gemdbj Proteomics)<br />
Mutsumi Hosako (Proteome Bioinformatics Project, National Cancer Center<br />
Research Institute, JAPAN), Masayo Yamada, Setsuo Hirohashi, Tadashi Kondo<br />
How Bioinformatics Helps To Achieve And Publish Proteomics Results Following<br />
Publications Guidelines<br />
Deltev Suckau, Peter Hufnagel (Bruker Daltonik GmbH, GERMANY), Ulrike<br />
Schweiger-Hufnagel, Jörg Glandorf, Herbert Thiele, Stefan Weise, Martin Blüggel<br />
P-WED-165<br />
P-WED-166<br />
Integrated Bioinformatics For Biodefense Proteomics<br />
Cathy Wu (Protein Information Resource, UNITED STATES)<br />
Miapegeldb: A Web-Based Submission Tool And Public Repository For Miape Gel<br />
Electrophoresis Documents<br />
Robin Xavier (University of Geneva / Swiss Institute of Bioinformatics,<br />
SWITZERLAND), Christine Hoogland, Ron D. Appel, Frederique Lisacek<br />
P-WED-154<br />
An Integrated Protein Repository For Mining Proteomics Data<br />
Christian Ingrell (Proxeon A/S, DENMARK), Peter Venø, Morten Bern<br />
140 141
Kinase-Protein Substrate Networks<br />
P-WED-167<br />
P-WED-168<br />
P-WED-169<br />
P-WED-170<br />
P-WED-171<br />
Establishing A Kinase Rnai Screen To Investigate Recruitment Of Human<br />
Kinetochore Proteins Mcm21/Cenp-O and Chl4/Cenp-N<br />
Mukta Belwal (Eth Zürich, SWITZERLAND)<br />
Cck Stimulates Peptide Chain Elongation In Mouse Pancreatic Acini And The<br />
Molecular Mechanism<br />
Chaojun Duan (Xiangya Hospital, Central South University, CHINA)<br />
Screen Biomarkers From Human Nasopharyngeal Carcinoma Serum Using A<br />
Proteomics Approach<br />
Chaojun Duan (Xiangya Hospital, Central South University, CHINA)<br />
Nuclear Plcbeta1 Signaling: eef1a2 Is A Novel Phospho-Substrate Of Pkcbeta1<br />
In Myoblast<br />
Manuela Piazzi (Cellular Signalling Laboratory, Department of Anatomical Sciences,<br />
University of Bologna / Cell Biology and Electron Microscopy Laboratory, ITALY),<br />
Alberto Bavelloni, Gabriella Cioffi, Simona D’Aguanno, Andrea Urbani, Nadir Mario<br />
Maraldi, Lucio Cocco<br />
Selective Enrichment And Quantitation Of Phosphoproteins Involved In Cell Proliferation<br />
Michael Major, Rosa Viner, Michael Rosenblatt, Terry Zhang, Vlad Zabrouskov, Sarah<br />
Klipp, Navid Haghdoost (Thermo Scientific, UNITED STATES), Barbara Kaboord, John<br />
Rogers<br />
Proteome Biology Of Infectious Diseases<br />
P-WED-172<br />
P-WED-173<br />
P-WED-174<br />
P-WED-175<br />
P-WED-176<br />
P-WED-177<br />
P-WED-178<br />
P-WED-179<br />
Large Scale Analysis Of Cross Presented Hla Class I Peptides<br />
Michal Bassani-Sternberg, Arie Admon (Technion-Israel Institute of Technology, ISRAEL)<br />
A Proteomic Analysis Of Biofilm Induced By Bile Salts In Vibrio Cholerae O1<br />
Livia Barbosa, Paulo Mascarello Bisch (Unidade Multidisciplinar de Genômica, Rede<br />
Proteoma Do Rio de Janeiro – Ibccf, Ufrj, BRAZIL), Wanda von Krüger<br />
Identification Of The Spi2 Effector Interactome In The Salmonella Cell<br />
Nat Brown (Griffith University, AUSTRALIA), Scott Nankervis, Lindsay Rogers,<br />
Leonard Foster<br />
Proteomes Of Non-Pylori Helicobacter: The Search For Pathogenic Determinants<br />
Winita Fowsantear, Evelyn Argo, Cheryl Ritchie, ElIzabeth Stewart, Emad El-Omar,<br />
Georgina Hold, Phil Cash (University of Aberdeen, UNITED KINGDOM)<br />
New Insights In Dendritic Cells Funtionning Are Revealed By Proteomics<br />
Thierry Rabilloud, Mireille Chevallet (Cea / Irtsv / Lbbsi, FRANCE), Christian Villiers,<br />
Hélène Diemer, Patrice Marche, Alain van Dorssealer<br />
Quorum Sensing Contributes To Proteomic Changes Of Enterohemorrhagic<br />
Escherichia Coli O157:H7<br />
Seung-Hak Cho (Korean National Institute of Health, KOREA), Jong-Chul Kim, Bok<br />
Kwon Lee<br />
Bile Stress Response Of The Enteric Pathogen Vibrio Cholerae<br />
Rukhsana Chowdhury (Indian Institute of Chemical Biology, INDIA), Tanusree Das<br />
Proteomic Analysis Of Nuclear Enriched Fractions From Hcc Liver Tissues<br />
Erika Codarin (Department of Biomedical Sciences and Technologies, University of<br />
Udine, ITALY), Chiara D’Ambrosio, Andrea Scaloni, Laura Cesaratto, Carlo Vascotto,<br />
Umberto Baccarani, Claudio Avellini, Claudio Tiribelli, Franco Quadrifoglio, Gianluca Tell<br />
P-WED-180<br />
P-WED-181<br />
P-WED-182<br />
P-WED-183<br />
P-WED-184<br />
P-WED-185<br />
P-WED-186<br />
P-WED-187<br />
P-WED-188<br />
P-WED-189<br />
P-WED-<strong>19</strong>0<br />
P-WED-<strong>19</strong>1<br />
Identification Of Herpes Simplex Virus Type 1 Signaling Targets In Human<br />
Hepatoma Cells By Functional Organelle Proteomics<br />
Fernando Corrales (Foundation for Applied Medical Research (Fima), SPAIN), Enrique<br />
Santamaría, Corinne Potel, Joaquín Fernández-Irigoyen, Rubén Hernández-Alcoceba,<br />
Alberto Epstein<br />
Validating Divergent Orf Annotation In M. Tuberculosis Datasets Using A Ltq-<br />
Orbitrap<br />
Gustavo de Souza (Gades Institute, Dept. of Immunology and Microbiology, Uib,<br />
NORWAY), Hiwa Malen, Tina Softland, GisLe Saelesminde, Inge Jonassen, Harald<br />
Wiker<br />
Adaptation Of E.Coli Protein Expression In The Mouse Gastrointestinal Tract<br />
Wolfram Engst (German Institute of Human Nutrition Potsdam-Rehbrücke,<br />
GERMANY), Carl Alpert, Jacqueline Scheel, Gunnar Loh, Michael Blaut<br />
Withdrawn<br />
Proteomic Analysis Of Mycoplasma Penetrans Membrane<br />
Mario Ferrer-Navarro (Institut de Biotecnologia I Biomedicina, SPAIN), Raquel<br />
Planell, Sílvia Bronsoms, Núria Colomé, Francesc Canals, Francesc Xavier Aviles,<br />
Enrique Querol<br />
Proteomic Study Of Tyk2 Deficient Murine Macrophages In Response To Poly I:c<br />
Tom Grunert (Institute of Chemical Technologies and Analytics, Vienna University<br />
of Technology / Institute of Animal Breeding and Genetics, University of Veterinary<br />
Medicine, AUSTRIA), Birgit Strobl, Martina Marchetti, Ingrid Miller, Marta Radwan,<br />
Claus Vogl, Manfred Gemeiner, Günter Allmaier, Mathias Müller<br />
The Secreted Proteome Of Epidemic Cystic Fibrosis (Cf) Pseudomonas<br />
Aeruginosa Aes-1<br />
Nathan Hare (School of Molecular and Microbial Biosciences, University of Sydney,<br />
AUSTRALIA), Colin Harbour, Barbara Rose, Stuart Cordwell<br />
Altered Proteome In Human Endothelial Cells During Dengue Virus Infection<br />
Rattiyaporn Kanlaya (Department of Immunology and Immunology Graduate Program,<br />
Faculty of Medicine Siriraj Hospital, Mahidol University / Medical Molecular Biology<br />
Unit, Office for Research and Development, Faculty of Medicine Siriraj Hospital,<br />
Mahidol University, THAILAND), Sa-Nga Pattanakitsakul, Supachok Sinchaikul, Shui-<br />
Tein Chen, Visith Thongboonkerd<br />
Hcv Induced Cirrhosis: A Proteomic Approach<br />
Rizma Khan (University of Karachi, Pakistan), Saadia Zahid, Nikhat Ahmed, M Ataur<br />
Rahman<br />
Identification Of Immunogenic Proteins From Chlamydophila Pneumoniae Knih-1<br />
Kwang-Jun Lee (National Institute of Health, Kcdc, KOREA), Sung-Ha Park, Su-Jin<br />
Kwon, Young-Chang Kim, Yeon-Ho Kang<br />
Detection Of Phosphorylcholine-Modified Peptides By Precursor Ion Scanning<br />
And Mrm<br />
Christof Lenz, Julia Grabitzki, Günter Lochnit, Donna Potts (Applied Biosystems,<br />
GERMANY)<br />
Dissecting Phosphorylcholine-Modified Proteins In The Parasite Plasmodium<br />
Falciparum<br />
Julia Grabitzki, Sascha Koncarevic, Katja Becker, Guenter Lochnit (Institute of<br />
Biochemistry, University Giessen, GERMANY)<br />
142 143
P-WED-<strong>19</strong>2<br />
P-WED-<strong>19</strong>3<br />
P-WED-<strong>19</strong>4<br />
Proteomic Profile Of The Upper Airways Of Children Suffering Viral Infection<br />
Luis M. Teran (Instituto Nacional Enfermedades Respiratorias, Mexico), Sabrina<br />
Rüggeberg, Jose Luis Hernandez, Thomas Franz<br />
Proteomic Analysis Of Cytoplasmic And Surface Proteins From Yeast Cells,<br />
Hyphae, And Biofilms Of Candida Albicans<br />
Martínez-Gomariz Montse (Unidad de Proteómica, Pcm-Ucm, SPAIN), Perumal<br />
Palani, Mekala Satish, Nombela César, Chaffin W. Lajean, Gil Concha<br />
Direct Identification Of Uropathogens In Urine Samples With Maldi-TOF-Ms<br />
Frank Mosel (Institute of Hygiene and Occupational Medicine, GERMANY)<br />
P-WED-206<br />
P-WED-207<br />
P-WED-208<br />
Proteomic Analysis Of The Antibiotic Response Of Stenotrophomonas Maltophilia<br />
Laurence van Oudenhove (L-Probe, Ugent, BELGIUM)<br />
Dynamics Of The Proteomes Of Mammalian Cell Lines During Influenza A Virus<br />
Infection<br />
Diana Vester (Bioprocess Engineering, Otto-Von-Guericke University Magdeburg,<br />
GERMANY), Erdmann Rapp, Yvonne Genzel, Doerte Gade, Udo Reichl<br />
Quantitative Proteomics Analysis Of Human Macrophage Activation<br />
Sara Vosmaer (University Medical Centre Groningen / Centre for Medical Biomics,<br />
THE NETHERLANDS), Marcel de Vries, Roel Vonk, Han Roelofsen<br />
P-WED-<strong>19</strong>5<br />
P-WED-<strong>19</strong>6<br />
P-WED-<strong>19</strong>7<br />
P-WED-<strong>19</strong>8<br />
P-wed-<strong>19</strong>9<br />
P-WED-200<br />
P-WED-201<br />
P-WED-202<br />
P-WED-203<br />
P-WED-204<br />
P-WED-205<br />
Protein Expression Patterns In Adult Angiostrongylus Costaricensis Nematode<br />
Ana Neves-Ferreira (Laboratório de Toxinologia, Instituto Oswaldo Cruz, BRAZIL), Juliana<br />
São Luis, Ester Mota, Ileana León, Richard Valente, Henrique Lenzi, Jonas Perales<br />
Proteomics To Characterise Activation Of Innate Immunity In Human Keratinocytes<br />
Tuula Nyman (Institute of Biotechnology, FINLAND), Tiina Öhman, Niina LIetzén,<br />
Rauna Tanskanen, Sampsa Matikainen<br />
Proteome Characterization Of Influenza A Virus Infected Human Primary<br />
Macrophages<br />
Tiina Öhman (Institute of Biotechnology, University of Helsinki, FINLAND), Johanna<br />
Rintahaka, Sampsa Matikainen, Tuula Nyman<br />
Plasmodium Knowlesi And Rheses Red Blood Cell Proteomics<br />
Erica Pasini (Biomedical Primate Research Centre, THE NETHERLANDS), Matthias<br />
Mann, Alan Thomas<br />
Proteomic Analysis Of Host Responses In Human Foreskin Fibroblast Cells During<br />
Dengue Virus Infection<br />
Sa-Nga Pattanakitsakul (Medical Molecular Biology Unit, Office for Research and<br />
Development, Faculty of Medicine Siriraj Hospital, Mahidol University, THAILAND),<br />
Kamonthip Rungrojcharoenkit, Rattiyaporn Kanlaya, Supachok Sinchaikul, Shui-Tein<br />
Chen, Visith Thongboonkerd<br />
Withdrawn<br />
Proteomics And Its Role In The Clinical Diagnosis Diseasea<br />
Maryam Saleh (Pasteur Institute of Iran, Iran)<br />
Fungal Pathogen Pseudallescheria Boydii Secreted Proteins Characterization<br />
Jan Sklenar (Institute of Microbiology, CZECH REPUBLIC), Bara Fliedrova, Vladimir<br />
Havlicek<br />
From Target Identification To Drug Discovery: The Hiv-1 / Human Ledgf - Case Study<br />
Petra Tafelmeyer (Hybrigenics Sa Services, FRANCE), Philippe Guedat, Jean-<br />
Christophe Rain, Etienne Formstecher, Fanny Moisant, Anne Pecquery-Texier,<br />
Richard Benarous, Sabine Barbey, Jean-Marc Paris, Stephane Emiliani<br />
Effectors Molecules Secreted By The Obligate Intercelluar Pathogen Coxiella<br />
Burnetti<br />
Georgios Tsiotis (University of Crete, Dept. Of Chemistry, Greece), Georgios Samoilis,<br />
Michalis Aivaliotis, Iosif Vranakis, Anastasia Papadioti, Anna Pasroulaki, Yannis Tselentis<br />
Optimized Alkaline Proteome Mapping Of The Human Parasite Trypanosoma Cruzi<br />
Marcelo Valle de Sousa (University of Brasilia, BRAZIL), Adriana Magalhães, Sebastien<br />
Charneau, Jaime Paba, Rafael Guercio, Jaime Santana, Antonio Teixeira, Carlos<br />
André Ricart<br />
Proteomics and Epigenetics<br />
P-WED-209<br />
P-WED-210<br />
P-WED-211<br />
P-WED-212<br />
P-WED-213<br />
P-WED-214<br />
P-WED-215<br />
P-WED-216<br />
P-WED-217<br />
On The Protein Profile Of Pxe Fibroblasts: From Genetic To Epigenetic<br />
Pathogenesis<br />
Federica Boraldi (University of Modena and Reggio Emilia, ITALY), Giulia Annovi,<br />
Deanna Guerra, Roberta Tiozzo, Ivonne Pasquali-Ronchetti, Daniela Quaglino<br />
Differential Proteomics For Priamry And Secondary Polyposis And Cftr Network.<br />
Ludovic Jeanson, Chiara Guerrera, André Coste, Estelle Escudier, Serge Amselem,<br />
Aleksander Edelman (Inserm / Université Paris Descartes / Plateau Proteome<br />
Necker, FRANCE)<br />
Searching For Proteins Involved In Lymphoma: A Network Of Proteomic And<br />
Transcriptomic Clues<br />
Anouk Emadali (Cea, Dsv, Irtsv, Laboratoire D’Etude de la Dynamique Des<br />
Protéomes, FRANCE), Sylvie Kieffer, Christophe Masselon, Mary Callanan, Sophie<br />
Rousseaux, Saadi Khochbin, Jérôme Garin, Myriam Ferro<br />
Proteomic Analysis Of Protein Complement During Honeybee (Apis Mellifera)<br />
Drone Egg Development<br />
Jianke Li (Institute of Apicultural Research, Chinese Academy of Agircultural<br />
Science, CHINA)<br />
Proteomic Analysis To Evaluate The Effects On Colon Cancer Cells Of A Novel<br />
Hdac Inhibitor<br />
Alberto Milli (Universitã Degli Studi di Verona, Dip. Scientifico E Tecnologico,<br />
Laboratorio di Proteomica, ITALY), Daniela Cecconi, Lello Zolla, Franco Zunino,<br />
Federico Odreman, Pier Giorgio Righetti<br />
Human Corneal Epithelial Cell Migration: An Epigenetic Approach<br />
Syed Zulfiqar Ali Naqvi (Neurochemistry Research Unit, Department of<br />
Biochemistry, University of Karachi / Research Laboratory, Department of Biological<br />
& Biomedical Sciences, Aga Khan University, Pakistan), Shamim Mushtaq, Anwar<br />
Ali Siddiqui, Nikhat Ahmed<br />
A Mass Spectrometric Analysis Of Embryonic Zebrafish Proteins<br />
Angel Pizarro (University of Pennsylvania, UNITED STATES), Margaret Lucitt, Tom<br />
Price, Tilo Grosser, Weichen Wu, Anastasia Yocum, Christoph Seiler, Michael Pack,<br />
Ian Blair Blair, Garret Fitzgerald<br />
Proteomic Analysis Of Models Of Ovarian Cancer Tumour Suppression<br />
John Sinclair (Ucl, UNITED KINGDOM)<br />
Efficient Procedures For Avoiding Human Keratin Contaminations During 2d Gel<br />
Proteomics Analysis<br />
Bo Xu (Niigata University, JAPAN), Zongjiang Zhao, Ying Zhang, Yutaka Yoshida,<br />
Eishin Yaoita, Tadashi Yamamoto<br />
144 145
Proteomics Of The Nervous Systems<br />
P-WED-218<br />
P-WED-2<strong>19</strong><br />
P-WED-220<br />
P-WED-221<br />
Enhanced Peptide Extraction In Combination With Targeted Ms For Improved<br />
Identification Of The Nervous Tissue Peptidome<br />
Maarten Altelaar (Biomolecular Mass Spectrometry and Proteomics Group, Utrecht<br />
University, THE NETHERLANDS), Shabaz Mohammed, Roger Adan, Albert Heck<br />
Withdrawn<br />
Neuropeptidomic And Imaging Ms Strategies For Studying Experimental<br />
Parkinson’s Disease<br />
Per Andren (Uppsala University, SWEDEN), Maria Falth, Anna Nilsson, Karl Skold,<br />
Marcus Svensson, Mats Boren, Malin Andersson, David Fenyo, Per Svenningsson<br />
Seldi-Tof Ms and MALDI-TOF-Tof Ms Detection Of Proteomic Biomarkers For<br />
Glaucoma In Neuroretinal Cells<br />
Katharina Bell (Experimental Ophthalmology, Dept. of Ophthalmology, University of<br />
Mainz, GERMANY), G Seigel, N Pfeiffer, FH Grus<br />
P-WED-229<br />
P-WED-230<br />
P-WED-231<br />
P-WED-232<br />
Protein Expression Changes Involved In Early Mitochondrial Dysfunction In<br />
Senescence-Accelerated Mouse Revealed By Comparative Proteomic Analysis<br />
Jianguo Ji (Department of Biochemistry and Molecular Biology, College of Life<br />
Sciences, National Laboratory of Protein Engineering and Plant Genetic Engineering,<br />
Peking University, CHINA)<br />
Quantitative Proteomics Analysis Of Specific Carbonylated Proteins In The<br />
Temporal Lobe Of Aged Rat: The Deterioration Of Antioxidant System<br />
Shaoyi Ji (The National Laboratory of Protein Engineering and Plant Genetic<br />
Engineering, College of Life Sciences, Peking University, CHINA)<br />
Comprehensive Analysis Of Human And Chimpanzee Brain Proteomes<br />
Philipp Khaitovich (Cas-Mpg Institute for Computational Biology, CHINA), Xing Fu,<br />
Ning Fu, Wei Chen, Svante Paabo, Rong Zeng<br />
Interindividual Differences In Protein Identities And Abundances In Cerebrospinal<br />
Fluid Of Controls<br />
Robert-Jan Lamers (Erasmus Mc, THE NETHERLANDS)<br />
P-WED-222<br />
P-WED-223<br />
P-WED-224<br />
P-WED-225<br />
Identification Of Novel Abeta/App Isoforms In Human Cerebrospinal Fluid And<br />
Plasma<br />
Ann Westman-Brinkmalm (Clinical Neurochemistry Laboratory, Sahlgrnska University<br />
Hospital, SWEDEN), Erik Portelius, Gunnar Brinkmalm, Henrik Zetterberg, Kaj<br />
Blennow<br />
Reliable Biostatistical Analysis Of Differentially Expressed Spots From 2-De Gels<br />
Oliver Broedel (A+M Proteome Science Berlin, GERMANY), Ulrich Mansmann, Murat<br />
Eravci, Stephanie Weist, Andreas Baumgartner<br />
Pi Injuring Effect On A Dopaminergic Nb Cell Line Model And Estradiol Rescue<br />
Annamaria D’Alessandro (Santa Lucia Foundation-Irccs, Section of Proteomics and<br />
Metabonomics / University of Rome “Tor Vergata”, ITALY), Simona D’Aguanno, Maria<br />
Teresa Cencioni, Adamo Diamantini, Luca Battistini, Luisa Pieroni, Sergio Bernardini,<br />
Giorgio Federici, Andrea Urbani<br />
Quantitative Analysis Of Differentially Expressed Brain Proteins In The Eae-<br />
Model For Multiple Sclerosis<br />
Ruth Daniels (Hasselt University, Biomedical Research Institute (Biomed) and<br />
Transnationale Universiteit Limburg, School of Life Sciences, BELGIUM), Annelies<br />
Vanheel, Kurt Baeten, Jerome Hendrix, Johan Robben, Jean-Paul Noben, Piet<br />
Stinissen<br />
P-WED-233<br />
P-WED-234<br />
P-WED-235<br />
P-WED-236<br />
P-WED-237<br />
Longitudinal Analysis Of Csf In The Assessment Of Alzheimer’s Disease Ivig<br />
Immunotherapy<br />
Kelvin Lee (University of Delaware, UNITED STATES), Leila Choe, Norman Relkin<br />
Comparative Proteome Analysis Of Rat Spinal Cord Protein Expression After<br />
Severe Traumatic Injury<br />
Cui Li (Department of Neurosurgery, Xiangya Hospital, Central South University,<br />
CHINA), Xuejun Li, Lan Gu<br />
Protein Profiling Of Guillain-Barre’ Patients Cerebrospinal Fluid By 2de And Ms<br />
Santina Lupisella (Centro Europeo Ricerca Sul Cervello, Irccs-Fondazione Santa<br />
Lucia / Dipartimento di Medicina di Laboratorio, Policlinico di Tor Vergata, ITALY),<br />
Simona D’Aguanno, Gian Vico Melzi D’Eril, Alessandra Barassi, Diego Franciotta,<br />
Alessandra Lugaresi, Sergio Bernardini, Andrea Urbani, Giorgio Federici<br />
Gfap Is Lipoxidated In Frontotemporal Lobar Degeneration<br />
Anna Martinez (Universitat de Barcelona, SPAIN), Anna Gómez, Isidre Ferrer<br />
Amyloid Precursor Protein Intracellular Domain (Aicd) - Dependent Modulation<br />
Of Protein Abundance<br />
Thorsten Müller (Medizinisches Proteom Center, Funktionelle Proteomik, Ruhr-<br />
University Bochum, GERMANY), Anna Ulrich, Katrin Marcus<br />
P-WED-226<br />
P-WED-227<br />
Quantitative Analysis Of 5 Subcellular Fractions From Rat Brain By 2-D Gel<br />
Electrophoresis<br />
Murat Eravci (Department of Radiology and Nuclear Medicine (Radiochemistry),<br />
Charité Universitätsmedizin / A+M Proteome Science, GERMANY), Oliver Broedel,<br />
Stephanie Weist, Selda Eravci, Andreas Baumgartner<br />
Oxidation Of Glycolitic Enzymes In Frontal Cortex Occurs In Aging And Is<br />
Increased In Dlb<br />
Anna Gomez (Universitat de Barcelona, SPAIN)<br />
P-WED-238<br />
P-WED-239<br />
Altered Protein Expression In The Brain Of Alzheimer’s Disease Mouse Model,<br />
Appswe/Ps1de9<br />
Choongseob Oh (Gwangju Institute of Science & Technology (Gist), KOREA),<br />
Hyunwoo Choi, Eun Sil Park, Jong Hyuk Yoon, Zee-Yong Park, Yung Joon Yoo<br />
Proteomic Profiling Of Human Ventricular Cerebrospinal Fluid<br />
Peter Pingerelli, Haroon Saleem, Victor Ozols, Becky Duffy, Charles Adler, Thomas<br />
Beach, Holly Shill, Marwan Sabbagh, John Caviness, Richard Burns (Barrow<br />
Neurological Institute, UNITED STATES)<br />
P-WED-228<br />
Immune Response Biomarker Profiling In Glaucoma Patients By Means Of Protein<br />
Micro-Arrays (Protoarray)<br />
Franz Grus (Experimental Ophthalmology, Dept. of Ophthalmology, University of<br />
Mainz, GERMANY), D Buhr, Lissa Freeman-Cook, Nils Boehm, Norbert Pfeiffer<br />
P-WED-240<br />
P-WED-241<br />
Proteomic Approach To Determination Of Relative Expression Of Vdac Isoforms<br />
Mirele Daiana Poleti (Universidade de São Paulo, BRAZIL), Carla Rossini Crepaldi, Andrea<br />
Cristina Tesch, Flávia Simone Munin, Marcelo Cerqueira César, Marcos Nogueira Eberlin<br />
Neuropeptidomic Analysis In Embryonic Quail Diencephalon<br />
Birger Scholz (Department of Pharmaceutical Biosciences, Centre for Reproductive<br />
Biology, Uppsala University, SWEDEN), Henrik Alm, Anna Mattsson, Anna Nilsson,<br />
Mikhail Savitski, Maria Fälth, Kim Kultima, Karl Sköld, Per E Andren, Lennart Dencker<br />
146 147
P-WED-242<br />
P-WED-243<br />
P-WED-244<br />
P-WED-245<br />
P-WED-246<br />
P-WED-247<br />
P-WED-248<br />
P-wed-249<br />
P-WED-250<br />
P-WED-251<br />
Test Of Protein Extraction Systems For Downstream Protein Profiling Studies<br />
With Magnetic Beads<br />
Susanne Schwonbeck (Cea / Institut de Genomique, Centre National de Genotypage,<br />
FRANCE), Duong Nguyen Thi Thuy, Ivo G. Gut<br />
Profiling Of Csf By MALDI-Tof Mass Spectrometry: Assessment Of Magnetic<br />
Bead Based Enrichment<br />
Somdutta Sen (The Centre for Genomic Application, INDIA), Reena Arora, Sagarika<br />
Haldar, Jaya Sivaswami Tyagi, Neera Sharma, Vijay Kumar Gupta, Krishnamoorthy<br />
Narayanasamy<br />
Exploring The Cerebral Hypoxome<br />
Roos van Elzen (University of Antwerp, BELGIUM), Bart Ghesquière, Evy Timmerman,<br />
Kris Geveart, Sylvia Dewilde, Luc Moens<br />
Explorative Proteomics And Metabolomics Of Human Csf Following Pk-Pd<br />
Analyses<br />
Alain van Gool (Organon, A Part of Schering-Plough Corporation, THE NETHERLANDS),<br />
Benno Ingelse, Maarten Sollewijn Gelpke, Huub-Jan Kleijn, Sushmita Mimi Roy, Chris<br />
Becker, Felice de Jong, Danny Alexander, Jacques Schipper<br />
Lc-MALDI Profiling Analysis Of Csf<br />
Judith Barends (Organon, A Part of Schering-Plough Corporation, THE NETHERLANDS),<br />
Maarten Sollewijn Gelpke, Alain van Gool, Eckhard Belau, Detlev Suckau, Sven Brand<br />
Cognitive Performance And Age-Related Changes In The Hippocampal Proteome<br />
Willard Freeman, Heather Vanguilder (Penn State College of Medicine, UNITED<br />
STATES), Willard Freeman<br />
Effects Of Ifn-Beta On Astrocytes: A Proteomic And Nanotechnological<br />
Approach<br />
Daniele Vergara (National Nanotechnology Laboratory of Infm-Cnr, Isufi,<br />
University of Salento, ITALY), Roberta Martignago, Stefano Leporatti, Francesco de<br />
Nuccio, Giuseppe Nicolardi, Rosaria Rinaldi, Michele Maffia<br />
Proteomic Analysis Of Hippocampal Remapping<br />
Evelyn Wang (Exelixis, Inc., UNITED STATES)<br />
Effects Of Different Post Mortem Conditions On The Proteome Of 11 Rat Brain<br />
Areas<br />
Stephanie Weist (A+M Proteome Science, GERMANY), Murat Eravci, Oliver Broedel,<br />
Selda Eravci<br />
Toward A Better Understanding Of Human Brain Proteome: Membrane Proteome<br />
Analysis Of Brain Regions Using 2de<br />
Saadia Zahid (Neurochemistry Research Unit, Department of Biochemistry,<br />
University of Karachi, Pakistan), Rizma Khan, Afshan Wasti, AR Asif, Ahsana Dar,<br />
Nikhat Ahmed<br />
Quantification Ii<br />
P-WED-252<br />
P-WED-253<br />
P-WED-254<br />
P-WED-255<br />
P-WED-256<br />
P-WED-257<br />
P-WED-258<br />
P-WED-259<br />
P-WED-260<br />
P-WED-261<br />
P-WED-262<br />
Evaluation Of Label-Free Proteomics For Comprehensive Proteome Studies<br />
Sebastian Link (Medizinisches Proteom-Center, Ruhr-University Bochum,<br />
GERMANY), Barbara Sitek, Birgit Korte, Christian Stephan, Wolfgang Jabs, Carsten<br />
Baessmann, Martin Blueggel, Daniel Chamrad, Helmut E. Meyer, Kai Stuehler<br />
Rapid Sample Processing For Quantitative Proteomics Using High Intensity<br />
Focused Ultrasounds<br />
Daniel Lopez-Ferrer (Pacific Northwest National Laboratory, UNITED STATES), Tyler<br />
Heibeck, Konstantinos Petritis, Kim Hixson, Weijun Qian, Matthew Monroe, Anoop<br />
Mayampurath, Mikhail Belov, David Camp, Richard Smith<br />
Quantification Of Glyoxalase I, A Biomarker For A Mouse Model Of Trait Anxiety<br />
Giuseppina Maccarrone (Max Planck Institute of Psychiatry, GERMANY), Susanne<br />
Ciniawsky, Boris Hambsch, Christiane Rewerts, BirgiT Bisle, Christoph Turck<br />
Quantification Of Insulin And Other Biosimilars At Microdosing Levels Using Lc-Ms/Ms<br />
Louis Maljers (Thermo Fisher Scientific, UNITED STATES), Jonathan Mcnally, Rohan Thakur<br />
Global Sumo2 Proteome Dynamics In Response To Heat Shock<br />
Ivan Matic (Department of Proteomics and Signal Transduction, Max Planck Institute<br />
for Bioch, GERMANY), Filip Golebiowski, Jürgen Cox, Matthias Mann, Ronald Hay<br />
Targeted Mass Spectrometry Of sirna Based Rna Interference On Gapdh At<br />
The Protein Level<br />
Sahana Mollah (Applied Biosystems, UNITED STATES)<br />
Culture-Derived Isotope Tag (Cdit) Is Powerful Technique For The Quantitative<br />
Proteomics<br />
Tatsuji Nakamura (Eisai Co., Ltd. Laboratory of Core Technology, JAPAN), Yoshiya<br />
Oda, Junro Kuromitsu<br />
Immunogenicity Testing In The Presence Of Excess Protein Therapeutic Using<br />
Immunoprecipitation And Quantitative Mass Spectrometry<br />
Hendrik Neubert (Pfizer Inc, UNITED KINGDOM), Chris Grace, Klaus Rumpel, Ian James<br />
Vems: A Software For Quantitation And Analysis Of 18o Labelled Peptides<br />
Miren Josu Omaetxebarria (University of The Basque Country, Biochemistry and<br />
Molecular Biology Department, SPAIN), Kerman Aloria, Jesus Maria Arizmendi, Rune<br />
Matthiesen<br />
Intelligent Use Of Retention Time For Higher Order Multiple Reaction Monitoring<br />
Multiplexing- Scheduled Mrm Algorithm<br />
Madalina Oppermann (Applied Biosystems, SWEDEN), Christie Hunter<br />
Endoplasmic Reticulum Stress In Insulin Producing Ins-1e Cells: A 2d-Dige Analysis<br />
Lut Overbergh (Legendo, Catholic University Leuven, BELGIUM), Wannes D’Hertog,<br />
Kasper Lage, Daen Hansen, Etienne Waelkens, Decio Eizirik, Chantal Mathieu<br />
P-WED-263<br />
P-WED-264<br />
Automating High-Throughput Srm Assays Without Sacrificing Sensitivity<br />
Scott Peterman (Thermo Fisher Scientific, UNITED STATES), Amol Prakash, Mary<br />
Lopez, David Sarracino, Bryan Krastins, Claire Dauly<br />
Quantitative Proteome Analysis Of Human Neuronal Cells Treated By Clostridium<br />
Botulinum C3exoenzyme<br />
Marika Victoria Muetzelburg, Fred Hofmann, Ingo Just, Andreas Pich (Hannover<br />
Medical School, Department of Toxicology, GERMANY)<br />
148 149
P-WED-265<br />
iTRAQ-Analysis Of A Cell Culture Model For Malignant Transformation<br />
Stephanie Pütz (Rudolf Virchow Center, Dfg Research Center for Experimental Biomedicine,<br />
University of Wurzburg, GERMANY), Andreas Böhm, Thorsten Stiewe, Albert Sickmann<br />
P-WED-278<br />
Lc-Ms Based Quantitation Of Proteins Separated By Gel-Electrophoresis<br />
Zoltan Szabo (Department of Medical Chemistry, University of Szeged, HUNGARY),<br />
Istvan Foldi, Judit Szeline Szomor, Tamas Janaky<br />
P-WED-266<br />
P-WED-267<br />
P-WED-268<br />
Comparative Analysis Of Urine Proteins By 2d-Hplc Via Fluorescence Detection<br />
Xiaoqiang Qiao (National Chromatographic R. &. A. Center, Dalian Institute of<br />
Chemical Physics, CHINA), Junfeng Ma, Lihua Zhang, Zhen Liang, Yukui Zhang<br />
Acute Proteomic Response Of Muscle To Prednisone And Testosterone<br />
Erica Reeves (Children’s National Medical Center, UNITED STATES)<br />
Application Of Qconcat Technology To Protein Quantification<br />
Jennifer Rivers (University of Liverpool, UNITED KINGDOM), Deborah Simpson,<br />
Simon Gaskell, Robert Beynon<br />
P-WED-279<br />
P-WED-280<br />
P-WED-281<br />
Cysteinyl Peptide Enrichment Combined With iTRAQ As An Alternative To Icat<br />
Vojtech Tambor (Institute of Molecular Pathology, CZECH REPUBLIC)<br />
Protein Quantitation Using Multiple Reaction Monitoring<br />
Ning Tang (Agilent Technologies, UNITED STATES), Christine Miller<br />
Protein Quantification Using Laser Induced Fluorescence Detector And Nanoesi-<br />
Ecd-Ms/Ms<br />
Caroline Tokarski, Claude Netter, Jocelyne Tahar, Christian Rolando (Université Des<br />
Sciences et Technologies de Lille, FRANCE)<br />
P-WED-269<br />
P-WED-270<br />
P-WED-271<br />
P-WED-272<br />
P-WED-273<br />
P-WED-274<br />
P-WED-275<br />
P-WED-276<br />
P-WED-277<br />
Vems: A Tool To Quantify iTRAQ Labeled Samples<br />
Eva María Rodríguez Suárez (Cicbiogune, SPAIN), Felix Elortza, Jose María Mato,<br />
Rune Matthiesen<br />
Cilair: A Novel, Quantitative Method To Study Tissue Secretome Changes<br />
Han Roelofsen (University Medical Centre Groningen, Centre for Medical Biomics,<br />
THE NETHERLANDS), Desiree Weening, Marcel de Vries, Annemieke Hoek, Roel J. Vonk<br />
Targeted Analysis Of The Proteome And Phosphoproteome Of The Human Hepatocyte<br />
Anke Schnabel (Medizinisches Proteom-Center, Ruhr-Universitaet Bochum,<br />
GERMANY), Elmar Langenfeld, Gorden Redlich, Bettina Serschnitzki, Nicolai Bache,<br />
Andreas Nussler, Ole Jensen, Ulrich Zanger, Helmut Meyer, Katrin Marcus<br />
Integrated Workflow For Biomarker Discovery, Assay Development And<br />
Validation Using Tandem Mass Tags<br />
Peter Schulz-Knappe (Proteome Sciences Plc, Uk / Proteome Sciences R&D GmbH<br />
& Co Kg, GERMANY), Karsten Kuhn, Darragh O´Brien, Malcolm Ward, Helen Byers<br />
Identification Of Microrna Targets By Pulsed Silac<br />
Bjoern Schwanhaeusser, Nadine Thierfelder, Zhou Fang, Manfred Gossen, Nikolaus<br />
Rajewsky, Matthias Selbach (Max Delbrueck Center for Molecular Medicine,<br />
GERMANY)<br />
Up-Regulation Of Glycolytic Enzymes In Proteins Secreted From Human Colon<br />
Cancer Cells With 5-Fluorouracil Resistance<br />
Young-Kyoung Shin (Cancer Research Institute and Cancer Research Center, Seoul<br />
National University / Research Institute and Hospital, National Cancer Center,<br />
KOREA), Byong Chul Yoo, Kyung Hae Jung, Jae-Gahb Park<br />
Proteome Analysis Of Lung Carcinoma Cell Line A549 Using Label-Free And Dige<br />
Techniques<br />
Barbara Sitek (Ruhr-Universitaet-Bochum, GERMANY), Sebastian Link, Birgit Korte,<br />
Christian Stephan, Wolfgang Jabs, Carsten Baesmann, Martin Blüggel, Daniel C.<br />
Chamrad, Helmut E. Meyer, Kai Stühler<br />
2d Liquid Fractionation Of Proteins For Quantitative Mass Spectrometry In<br />
Cancer Research<br />
Helena Skalnikova (Institute of Animal Physiology and Genetics As Cr, V.V.I., CZECH<br />
REPUBLIC), Jirina Martinkova, Petr Halada, Andreas Ekefjard, Daniel Enetoft,<br />
Michaela Zilvarova, PeTr Dzubak, Hana Kovarova<br />
Absolute Quantification Of Plasma And Serum Proteins: Gaucher Disease<br />
Diagnostic Markers<br />
Richard Sprenger (Academic Medical Center, THE NETHERLANDS), Craig Dorschel,<br />
Hans Vissers, Hans Aerts<br />
P-WED-282<br />
P-WED-283<br />
P-WED-284<br />
P-WED-285<br />
P-WED-286<br />
P-WED-287<br />
P-WED-288<br />
P-WED-289<br />
P-WED-290<br />
P-WED-291<br />
Top-Down Vs Bottom-Up Stable Isotope Based Proteomics For Protein Quantification<br />
Yury Tsybin (Biomolecular Mass Spectrometry Laboratory, Ecole Polytechnique<br />
Fédérale, SWITZERLAND), Thibaut Douche, Hisham Ben Hamidane, Michael Affolter,<br />
Martin Kussmann, Adrien Schmid<br />
Pitfalls In Silac Analysis. Illustration By The Identification Of Syk Kinase Substrates<br />
Romain Larive, Serge Urbach (Igf / Plateforme Protéomique, FRANCE), Kévin<br />
Contrepois, Joël Poncet, Patrick Jouin, Guilhem Mascré, Alain Sahuquet, Peter<br />
Coopman, Nadir Bettache<br />
Using Mascot Scores As Semiquantitative Measure In Proteomic Analyses Of<br />
Short-Chain Acyl-Coa Dehydrogenase (Scad) Deficiency Patients<br />
Søren Vang (Research Unit for Molecular Medicine, DENMARK), Christina Bak<br />
Pedersen, Johan Palmfeldt, Niels Gregersen<br />
Evaluating Isobaric Tandem Mass Tags For Quantitative Peptidomics.<br />
Peter Verhaert (Delft University of Technology, Department of Biotechnology, THE<br />
NETHERLANDS), Martijn Pinkse<br />
Profiling Of A1 Mes-C-Myc Mouse Embryonic Mesencephalon Cells By Data<br />
Independent Lc-Ms<br />
Angela Chambery, Johannes Vissers (Waters Corporation, Ms Technologies Center,<br />
UNITED KINGDOM), James I. Langridge, Luca Colucci-D’Amato, <strong>August</strong>o Parente<br />
Automated Optimization Of Triple Quadrupole Parameters For Nanoflow Lc/Ms<br />
Of Peptides<br />
Keith Waddell (Agilent Technologies, UNITED STATES), Christine Miller, Ning Tang, S Torvi<br />
Multiple Approaches To The Identification And Quantification Of The Human Liver<br />
Proteome<br />
Yuqin Wang (Swansea University, UNITED KINGDOM), Cathrin Sibert, Brian<br />
Davidson, Barry Fuller, William Griffiths<br />
Quantitative Proteomics By Lc-Ms/Ms Multiplex Analysis Of Guanidino-Labeled<br />
(Glad) Samples<br />
Patrice Waridel (University of Lausanne, SWITZERLAND), Francesco Brancia,<br />
Jachen Barblan, Manfredo Quadroni<br />
Withdrawn<br />
Transformation Of Ion Intensity Improves Peptide Quantification<br />
Xiaoyong Wu (Mcgill University, CANADA), Brian Carrillo, Pascal Pleynet, Daniel<br />
Boismenu, Sylvie Laboissiere, Robert Kearney, Robert Nadon<br />
150 151
Other<br />
P-WED-292<br />
P-WED-293<br />
Protease Proteomics - Meprin Alpha Releases Vesicular Integral-Membrane<br />
Protein Vip36<br />
Daniel Ambort (Department of Medical Biochemistry, University of Gothenburg,<br />
Sweden / Institute of Biochemistry and Molecular Medicine, University of Berne,<br />
SWITZERLAND), Daniel Stalder, Manfred Heller, Erwin E. Sterchi<br />
The Development Of Novel Computer Approaches For Diseases At Its<br />
Development In Lipid Peroxidation.<br />
Sukiasyan Astghik (State Engineering University of Armenia, Armenia), Kirakosyan<br />
Armen, Tadevosyan Artashes, Humbardzumyan Armen<br />
P-WED-304<br />
P-WED-305<br />
Proteomic Analysis Of Exosomes Secreted By Hepatocytes<br />
Javier Conde-Vancells, Felix Elortza (Proteomics Unit, Cic Biogune , SPAIN), Eva<br />
Rodríguez-Suárez, Rune Matthiesen, Nieves Embade, Esperanza González, Jose M.<br />
Mato, Juan M. Falcón-Pérez<br />
A Proteomic Approach On The Immunomodulatory Effects Of Tx527, A<br />
1,25-Dihydroxyvitamin D3 Analogue, In Human Dendritic Cells And T<br />
Lymphocytes<br />
Gabriela Ferreira (Laboratoryof Experimental Medicine and Endocrinology, Catholic<br />
University of Leuven (Kul), BELGIUM), Femke Baeke, Lut Overbergh, Evelyne van<br />
Etten, Kasper Lage, Daniel Hansen, Etienne Waelkens, Christopher Workman,<br />
Chantal Mathieu<br />
P-WED-294<br />
Penguin Plasma Proteomics: Differential Analyses According To The Metabolic Status<br />
Fabrice Bertile (Iphc-Dsa, Ulp, Cnrs, FRANCE), Laetitia Fouillen, Thierry Raclot,<br />
Alain van Dorsselaer<br />
P-WED-306<br />
Lc-Ms/Ms-Based Proteome Profiling In Dahnia Pulex And Daphnia Longicephala.<br />
Thomas Frohlich (University Munich - Genecenter - Lafuga, GERMANY), Georg J.<br />
Arnold, Christian Laforsch<br />
P-WED-295<br />
Two-Dimensional Protein Profile Of Human Follicular Fluid: Pregnant X Non-Pregnant<br />
Ricardo Bertolla (Federal University of Sao Paulo, BRAZIL), Paula Lopes, Edson Lo<br />
Turco, Agnaldo Cedenho<br />
P-WED-307<br />
Rapid On-Membrane Profiling Of Phosphoproteins Using The Piezoelectric<br />
Technology<br />
Masaru Furuta (Shimadzu Corporation, JAPAN), Tsuyoshi Nakanishi, Eiji Ando<br />
P-WED-296<br />
P-WED-297<br />
P-WED-298<br />
The Human Proteome Initiative, Providing A Complete Set Of Human Protein<br />
Sequences<br />
Lionel Breuza (Swiss Institute of Bioinformatics (Sib), SWITZERLAND), Amos<br />
Bairoch, Uniprot Consortium<br />
Complete De Novo Sequencing Of Allergenic Proteins Using Bottom-Up<br />
Proteomics And Accurate Moecular Mass Measurement By Fticr-Ms<br />
Monica Carrera (Instituto de Investigaciones Marinas (Iim), Consejo Superior de<br />
Investigaciones Cientificas (Csic), SPAIN), Benito Canas, Lorena Barros, Jesus<br />
Vazquez, Jose Manuel Gallardo<br />
Identification Of Ubiquitination Sites And Chain Architecture: The Hunt For Red<br />
K29<br />
Emma Carrick (Mrc Ppu, University of Dundee, UNITED KINGDOM), Nick Morrice<br />
P-WED-308<br />
P-WED-309<br />
P-WED-310<br />
Hepatocystin Is Not Secreted In Cyst Fluid Of Hepatocystin Mutant Polycystic<br />
Livers<br />
Esmé Waanders, Anke L.L. Lameris, Huub J.M. op den Camp, Wendy Pluk, Jolein Gloerich<br />
(Nijmegen Proteomics Facility, Radboud University Nijmegen Medical Center, THE<br />
NETHERLANDS), Simon P. Strijk, Joost P.H. Drenth<br />
Integration Of Proteomics With Metalloproteomics (Metallomics) And Genomics<br />
In Sequenced Model Organisms<br />
Jose Luis Gomez-Ariza (Universidad de Huelva, SPAIN)<br />
Integrated Plant Metabolomics By Fourier Transform Ion Cyclotron Resonance<br />
Mass Spectrometry<br />
Jun Han (University of Victoria – Genome Bc Proteomics Centre, CANADA), Ryan M.<br />
Danell, Dustin Lippert, Monica Elloitt, Jörg Bohlmann, Christoph H. Borchers<br />
P-WED-299<br />
P-WED-300<br />
P-WED-301<br />
P-WED-302<br />
Hepcidin Measurement, Using Seldi-Tof-Ms, In Clinically Relevant Samples<br />
Annalisa Castagna (University of Verona, ITALY), Natascia Campostrini, Claudia<br />
Bozzini, Michela Pasino, Fabiana Busti, Roberto Corrocher, Domenico Girelli<br />
Functional Role Of 0-Glcnac Modification On Nfkappab<br />
Jin Won Cho (Yonsei Univ. Dept of Biology, KOREA), Won Ho Yang, Sang Yoon Park,<br />
Do Hyun Kim<br />
Protein Microarray Based Target Identification Of Bioactive Protein<br />
Yoon Sun Cho (Chemical Genomics Laboratory, Department of Biotechnology, College<br />
of Life Science and Biotechnology, Yonsei University, KOREA), Hye Jin Jung, Ho<br />
Jeong Kwon, Jung Min Han, Sung Hoon Kim<br />
Proteome Analysis Of Sulfur-Reducing Hyperthermophilic Archaea Thermococcus<br />
Onnurineus Na1<br />
Chi-Won Choi (Korea Basic Science Institute, KOREA), Sung Ho Yun, Sang Oh Kwon,<br />
Sung Gyun Kang, Jung-Hyun Lee, Gun Wook Park, Jin Young Kim, Jong-Soon Choi,<br />
Seung Il Kim<br />
P-WED-311<br />
P-WED-312<br />
P-WED-313<br />
P-WED-314<br />
Method To Identify And Isolate Maturing B Cells In Neonatal Mice<br />
Jenny Hansson (Department of Biochemistry and Molecular Biology, University of<br />
Southern Denmark, Denmark / Nestlé Research Center, SWITZERLAND), Manuel<br />
Oliveira, Laurent Favre, Jalil Benyacoub, Stephanie Blum, Ole N. Jensen, Martin<br />
Kussmann<br />
Mass Spectrometric Analysis Of Sumoylation Of The Transcriptional Repressor Tel<br />
Paul Hensbergen (Lumc, Biomolecular Mass Spectrometry Unit, Dept. of<br />
Parasitology, THE NETHERLANDS), Guy Roukens, Mariam Halloul-Ramdhani, Alfred<br />
Vertegaal, Crina Balog, André Deelder, David Baker<br />
Engineered Antibody Mimics Selected Against Novel Proteomic Biomarkers Are<br />
High-Value Reagents<br />
Peter Hudson (Csiro, AUSTRALIA)<br />
Using Targeted Proteomics To Id Cellular Targets Of Oxidation In Type 1 Diabetes<br />
Karen Jonscher (University of Colorado Denver, UNITED STATES), Miriam Kornfeld,<br />
Gloria Ortiz, Bj Ada, Bjorn Schneidewind, Sonia Flores<br />
P-WED-303<br />
Pig As A Model Organism For Human Diseases<br />
Marianne Danielsen (University of Aarhus, DENMARK), Emøke Bendixen, Marius<br />
Codrea, Bent Jensen, Lone Rasmussen, Knud Larsen, Christian Bendixen, Jan<br />
Stagsted, Per Sangild, Andrew Kessel<br />
P-WED-315<br />
Identification Of Ca-Binding Proteins In Anabaena Sp Pcc7120 Using Proteomic<br />
Techniques<br />
Alberto Jorge-Garcia (Centro de Biologia Molecular Severo Ochoa, SPAIN), Francisco<br />
Leganes, Francisca Fernandez-Pinas<br />
152 153
P-WED-316<br />
P-WED-317<br />
Withdrawn<br />
Cold Acclimation In Synechocystis Pcc6803<br />
John Rowland (Durham University / Nepaf, UNITED KINGDOM), Joanne Robson,<br />
Jogadhenu Prakash, Glen Kemp, Achim Treumann, Norio Murata<br />
P-WED-328<br />
P-WED-329<br />
Full Genome Analysis Of T-Regulatory Cells Isolated From Cancer Patients<br />
Alexei Lupatov (V.N. Orechovich Institute of Biomedical Chemistry Rams , RUSSIAN<br />
FEDERATION)<br />
Withdrawn<br />
P-WED-318<br />
P-WED-3<strong>19</strong><br />
P-WED-320<br />
P-WED-321<br />
P-WED-322<br />
Proteomics Analysis For Vibration Effect On Acl Cells<br />
Ji-Hye Kim (Korea University, KOREA), Eun-Jeong So, Hyun-Jung Kim, Young-Kwon<br />
Seo, Jung-Keuk Park, Chan-Wha Kim<br />
Protein Identification By Means Of Coherent Two-Dimensional Infrared<br />
Spectroscopy<br />
David Klug (Imperial College London, UNITED KINGDOM), Frederic Fournier, Elizabeth<br />
Gardner, Paul Donaldson, Christian Loeffeld, Rui Guo, Keith Willison<br />
Investigation Of Low Culture Temperature Response In Cho-K1 Cells Using<br />
Proteomics Tools<br />
Niraj Kumar (National Institute for Cellular Biotechnology, Ireland), Patrick<br />
Gammell, Paula Meleady, Michael Henry, Niall Barron, Martin Clynes<br />
Exploration Of The Human Chondrocyte Proteome By A Dual Prefractionation<br />
Approach<br />
Stijn Lambrecht (Ghent University - Department of Rheumatology / Laboratory for<br />
Pharmaceutical Biotechnology, BELGIUM), Maarten Dhaenens, Gust Verbruggen,<br />
Dirk Elewaut, Dieter Deforce<br />
Identification Of Tomato Fruit Allergen Profiles By Two Proteomics Approaches<br />
Karola Lehmann (Proteome Factory Ag, GERMANY), Sabine Dölle, Margitta Worm,<br />
Dietmar Schwarz, Philipp Franken, Olivia Bässler, Wolfram Weckwerth, Christian<br />
Scheler<br />
P-WED-330<br />
P-WED-331<br />
P-WED-332<br />
P-WED-333<br />
P-WED-334<br />
Identification Of Delta Antigen Nuclear Localization Signal Interacting Cellular<br />
Proteins<br />
Marta Mendes (Unidade de Biologia Molecular, Centro de Malária E Outras Doenças<br />
Tropicais, Instituto de Higiene E Medicina Tropical, Universidade Nova de Lisboa,<br />
PORTUGAL), Carolina Alves, Sérgio Mota, Natália Freitas, Ana Casaca, Déborah<br />
Penque, Celso Cunha<br />
Validation Of Procedures For Ms Based Database Search Protocols For Protein<br />
Identification<br />
Jackie Mosely (Durham University, UNITED KINGDOM), Gavin O’Connor, Simon<br />
Cowen, Sarah Williams<br />
Role Of Albumin Precursor And Hsp70 Proteins In Wound Healing Of Corneal<br />
Epithelial Cells<br />
Shamim Mushtaq (University of Karachi, Pakistan)<br />
Analysis Of Ubr1 Targets In Patients With Johanson-Blizzard Syndrome And A<br />
Murine Model<br />
Karanam Narasimha Kumar (Department of Medicine A / Institute of Functional Genomics,<br />
Ernst-Moritz-Arndt-University Greifswald, GERMANY), Martin Zenker, Alexander<br />
Varshavsky, Christian Scharf, Elke Hammer, Markus M. Lerch, Uwe Völker, Julia Mayerle<br />
Proteomics Analysis Of Human Endothelial Cells Exposed To Mobile Phone Radiation<br />
Reetta Nylund (Stuk, FINLAND), Hanna Tammio, Niels Kuster, Dariusz Leszczynski<br />
P-WED-323<br />
P-WED-324<br />
Proteomic Analysis Of The Schistosome Proteins Released Into Host Serum<br />
Feng Liu (Shanghai-Most Key Laboratory of Health and Disease Genomics, Chinese<br />
National Human Genome Center at Shanghai / Shanghai Jiao Tong University School<br />
Of Medicine, CHINA), Wei Hu, Shu-Jian Cui, Zhi-Qin Wang, Ze-Guang Han<br />
Two-Dimensional Protein Profile Of Human Follicular Fluid: Endometriosis X Good<br />
Responders<br />
Edson lo Turco (Federal University of Sao Paulo, BRAZIL), Paula Lopes, Ricardo<br />
Bertolla, Maisa Sakata, Ismael Silva, Agnaldo Cedenho<br />
P-WED-335<br />
P-WED-336<br />
Comparison Of Carbonylated Peptide Enrichment Methods Optimized For Mass<br />
Spectrometry<br />
Angela Pereira da Rocha (Protein Research Group, Department of Biochemistry and<br />
Molecular Biology, University of Southern Denmark, DENMARK), Adelina Rogowska-<br />
Wrzesinska, Kenneth Bendix Jensen, Peter Roepstorff<br />
2-De Protein Analysis In Carboplatin Treated Human Renal Tubular Epithelial Cells<br />
Juliana Perez (Federal University of Sao Paulo, BRAZIL), Maisa Sakata, Ricardo<br />
Bertolla, Dulce Casarini<br />
P-WED-325<br />
P-WED-326<br />
P-WED-327<br />
Automated “In-Gel” And “On-Membrane” Digest For High-throughput Protein<br />
Identification<br />
Bjoern H. Bender (Institute of Biochemistry, University Giessen, GERMANY), Anne<br />
Wagner, Julia Grabitzki, Peter Kiesau, Brian Mcglothlen, Carsten Mang, Peter Engel,<br />
Guenter Lochnit<br />
Interfacing Capillary Electrophoresis And 2d-Infrared Spectroscopy For High<br />
Throughput Proteomics<br />
Christian Loeffeld (Imperial College London, UNITED KINGDOM), Frederic Fournier,<br />
Paul Donaldson, Miriam Goyder, Rafal Marszalek, Bo Zhang, Christopher Barnett,<br />
Keith Willison, David Klug<br />
Two-Dimensional Protein Profile Of Human Follicular Fluid: Good X Poor Ovarian<br />
Responders<br />
Paula Lopes (Federal University of Sao Paulo, BRAZIL), Ricardo Bertolla, Edson Lo<br />
Turco, Juliana Perez, Dulce Casarini, Agnaldo Cedenho<br />
P-WED-337<br />
P-WED-338<br />
P-WED-339<br />
P-WED-340<br />
P-WED-341<br />
Copmparision Between Different Protein Dectection Techniques For<br />
Polyacrylamid Gels<br />
Mario Pink (Institute of Hygiene and Occupational Medicine, University Hospital<br />
Essen, GERMANY), Albert W. Rettenmeier, Simone Schmitz-Spanke<br />
Combined Transcriptome/Peptidome Analysis From Odorrana Schmackeri, The<br />
Chinese Odorous Frog<br />
Martijn Pinkse (Delft University of Technology, Department of Biotechnology, THE<br />
NETHERLANDS), Geisa Caprini, Tienbao Chen, Peter Verhaert, Christopher Shaw<br />
Establishment Of A High-Throughput Generation System Of Monoclonal<br />
Antibodies Using Multiplexed Immunization And Antigen Microarrays<br />
Feifei Qi (Beijing Proteome Research Center, CHINA)<br />
Withdrawn<br />
Identification Of Novel Human Adipokines<br />
Anja Rosenow (Maastricht University, THE NETHERLANDS), Edwin Mariman, Johan<br />
Renes<br />
154 155
P-WED-342<br />
P-WED-343<br />
P-WED-344<br />
Mitochondrial Proteomic Alterations In Osteoarthritic Human Articular<br />
ChondrOcytes<br />
Cristina Ruiz-Romero (Osteoarticular and Aging Research Lab, Proteomics Unit.<br />
Biomedical Research Center, Ch Universitario Juan Canalejo, SPAIN), Vanessa<br />
Carreira, Silvia Remeseiro, Valentina Calamia, Jesús Mateos, María Fernández,<br />
Fausto Galdo, Fj Blanco<br />
Proteomic Analysis Of Human Chondrocytes Treated With Glucosamine And<br />
Chondroitin Sulfate<br />
V Calamia (Osteoarticular and Aging Research Laboratory. Proteomics Unit.<br />
Biomedical Research Center. Ch Universitario Juan Canalejo, SPAIN), C Ruiz-Romero,<br />
V Carreira, J Mateos, B Cillero-Pastor, E Montell, J Verges, Fj Blanco<br />
Differential Effects Of Il-1beta And Tnf-Alpha In The Protein Profile Of Human<br />
Normal Chondrocytes<br />
B Cillero-Pastor (Osteoarticular and Aging Research Lab. Biomedical Research<br />
Center, C.H.U. Juan Canalejo, SPAIN), MJ López-Armada, C Ruiz-Romero, J Mateos,<br />
M Lires-Deán, B Caramés, B Lema, FJ Blanco<br />
P-WED-353<br />
P-WED-354<br />
P-WED-355<br />
And Imaging Analysis For Size-Dependent Biological Behavior Of Silica-Nanoparticles<br />
Tomoaki Yoshikawa (Universitylaboratory of Pharmaceutical Proteomics, National<br />
Institute of Biomedical Innovation, JAPAN), Hiromi Nabeshi, Toshiki Sugita, Kazuya<br />
Nagano, Shin-Ichi Tsunoda, Yasuo Tsutsumi<br />
Placental Plasma Proteome Study Of Human Parturition<br />
Wei Yuan (University of Bristol, UNITED KINGDOM), Kate Heesom, Neil Avent,<br />
Andrés López Bernal<br />
Sensitive Detection Of Oligomeric Conformations Of Proteins By Proximity<br />
Ligation Assay<br />
C Annink (Uppsala University, SWEDEN), H Englund, S Darmanis, FE Pettersson,<br />
O Söderberg, D Sehlin, A Lord, L Nilsson, L Lannfelt, U Landegren and M Kamali-M<br />
P-WED-345<br />
Role Of Magnesium Supplementation In Post-Ischemic Acute Renal Failure<br />
Maisa Sakata (Federal University of Sao Paulo, BRAZIL), Juliana Perez, Ricardo<br />
Bertolla, Dulce Casarini<br />
P-WED-346<br />
Analysis Of Rho Gtpase Activation And Inhibition In A Multiplexed, Miniaturised<br />
Format<br />
Thomas Joos, Nicole Schneiderhan-Marra, Michael Schmohl (Nmi Natural and<br />
Medical Sciences Institute at The University of Tubingen, GERMANY), Stefanie<br />
Rimmele, Oliver Poetz, Peter Gierschik, Yoel Kloog<br />
P-WED-347<br />
Assessment Of Protein Alterations In Platelets Caused By Uvc-, Uvb- And<br />
Gamma-Irradiation<br />
Leif Steil (Interfaculty Institute of Genetics and Functional Genomics, Ernst-Moritz-<br />
Arndt University Greifswald, GERMANY), Thomas Thiele, Elke Hammer, Harald Mohr,<br />
Ulrich Pohl, Thomas Müller, Andreas Greinacher, Uwe Völker<br />
P-WED-348<br />
Proteomic Analysis Of Calcium Oxalate Monohydrate Crystal-Induced<br />
Cytotoxicity In Distal Renal Tubular Cells<br />
Visith Thongboonkerd (Medical Proteomics Unit & Medical Molecular Biology Unit,<br />
Office for Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol<br />
University, Thailand), Theptida SemaNgoen, Supachok Sinchaikul, Shui-Tein Chen<br />
P-WED-349<br />
A High-Throughput Strategy For Validation Of Antibodies Towards Unknown<br />
Proteins.<br />
Kenneth Wester (Dept of Genetics & Pathology, Uppsala University, SWEDEN), Anna<br />
Asplund, Caroline Kampf, Mathias Uhlen, Sophia Hober, Henrik Wernerus, Fredrik<br />
Ponten<br />
P-WED-350<br />
Fluorescent Proteins, Ocean’s Gift To Research And Biotechnology<br />
Krzysztof Wrzesinski (Protein Research Group, Department for Biochemistry and<br />
Molecular Biology, University of Southern Denmark, DENMARK), Nicolai Bache,<br />
Martin Røssel Larsen, Ole Thastrup, Peter Roepstorff Roepstorff<br />
P-WED-351<br />
Direct Visualization Of Fluorescent Signals In Protein Gels Using A Backlit Blue<br />
Light Plate<br />
Szu-Yu Wu (Institute of Applied Science and Engineering, Fu-Jen Catholic University,<br />
TAIWAN), Li-Te Chin, Li-Ming Chen, Han-Min Chen<br />
P-WED-352<br />
Multistep Approach For Ptms Analysis In An In-Gel Digest With MALDI-Ms/Ms<br />
Yuzo Yamazaki (Shimadzu Corporation, JAPAN), Masaki Yamada<br />
156 157
Look for career opportunities at<br />
www.netherlandsproteomicscentre.nl<br />
High-level proteomics research,<br />
technology development & transfer<br />
for biological and biomedical applications<br />
www.netherlandsproteomicscentre.nl<br />
Agilent in Proteomics<br />
Unique HPLC-Chip LCMS solutions for faster, easier<br />
and more flexible answers for proteomics workflow<br />
© Agilent Technologies Inc., 2008<br />
Our measure is your success.<br />
products | applications | <strong>software</strong> | services<br />
Join Agilent<br />
for an informative workshop on<br />
Proteomics Workflows<br />
Monday <strong>August</strong> 18 th , 2008<br />
12:30 – 14:00, Room B<br />
For registration, visit the Agilent display at booth #32/33.<br />
The New HPLC-CHIP 6530 QTOF<br />
and 6460 Triple Quadrupole<br />
Solutions for true ‘high def’<br />
accurate-mass protein ID and<br />
sensitive targeted peptide<br />
quantitation<br />
Information for Oral and<br />
Poster Presenters<br />
Oral Presentations<br />
Speakers should make sure that at least 4 hours before the start of the session,<br />
their PowerPoint presentations are uploaded in the Speaker Ready Room. Computers<br />
are available for a last minute check of the presentation and a technician will be there<br />
to assist.<br />
The Speaker Ready Room is located in Room M in the Forum Centre<br />
and will be open at the following hours:<br />
Saturday, 16 <strong>August</strong> 08.30 - 18.30 hrs<br />
Sunday, 17 <strong>August</strong> 08.30 - 17.00 hrs<br />
Monday, 18 <strong>August</strong> 06.30 - <strong>19</strong>.00 hrs<br />
<strong>Tuesday</strong>, <strong>19</strong> <strong>August</strong> 06.30 - 20.00 hrs<br />
Wednesday, 20 <strong>August</strong> 06.30 - 17.00 hrs<br />
Speakers are requested to be present in the meeting room at least 10 minutes prior<br />
to the start of the session to meet the chairperson and to check with the audio<br />
visual assistant. All meeting rooms are equipped with data projection, a PC and a<br />
laser pointer. Speakers are not allowed to bring their own laptop. The chairperson will<br />
time all presentations. It is essential that all presentations are kept to the program<br />
timetable.<br />
Poster Presentations<br />
Posters will be on display in the exhibition and poster area (Hall 10 of the RAI Convention<br />
Centre). From Monday to Wednesday, posters can be viewed during meeting breaks<br />
which are scheduled daily on the following hours:<br />
Morning break<br />
09.30 - 11.00 hrs<br />
Lunch break<br />
12.30 - 14.00 hrs<br />
Afternoon break 15.30 - 16.00 hrs<br />
We would like to ask all poster presenters to be present at their poster at least<br />
during the morning and afternoon break.<br />
All posters will be on display for one day only, either on Monday, <strong>Tuesday</strong> or Wednesday.<br />
Posters will be numbered as P-MON-#, P-TUE-# and P-WED-# respectively (see pages<br />
68 - 157).<br />
Posters must be put on the allocated poster board on the day of presentation between<br />
07.30 and 09.00 hrs. Poster numbers are printed on the poster boards. Fixing material<br />
will be available in the poster area. Posters should be removed from the poster boards<br />
between 16.00 and <strong>19</strong>.00 hrs.<br />
The organization will not be responsible for posters that are not removed in time, they<br />
will be discarded after the congress.<br />
158 159
Exhibition Information<br />
The 7th HUPO Annual World Congress expresses its warm thanks to our Exhibitors<br />
for supporting the Congress. We encourage all delegates to visit the Exhibition and to<br />
learn more about the products and services on show. The Exhibition is located in Hall<br />
10, accessible from the first floor of the congress centre. The booth numbers can be<br />
found on page 20 in this Final Program.<br />
Exhibition opening hours:<br />
Monday 18 <strong>August</strong><br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />
Wednesday 20 <strong>August</strong><br />
09.30 - <strong>19</strong>.00 hrs<br />
09.30 - 20.00 hrs<br />
09.30 - 16.00 hrs<br />
Exhibition Information / Registration Desk opening hours:<br />
Saturday 16 <strong>August</strong> 13.00 - 20.00 hrs<br />
Sunday 17 <strong>August</strong> 10.00 - 20.00 hrs<br />
Monday 18 <strong>August</strong> 08.00 - 13.00 hrs<br />
Wednesday 20 <strong>August</strong> 16.00 - 18.00 hrs<br />
General Information<br />
Abstracts<br />
The abstracts are available on a USB stick which is included in the registration package<br />
for registered delegates.<br />
Beach South<br />
Behind the Auditorium Centre you will find this upmarket city beach ‘Strand Zuid’<br />
(Beach South), with elegant beach furniture and a nice bar. It borders the Beatrix Park<br />
pond, no swimming is allowed but showers are available. DJ’s are playing there during<br />
the weekends. It is open during the Congress for lunch, dinner or just to relax!<br />
Coffee and tea breaks<br />
For registered participants wearing their name badges, coffee and tea during the<br />
breaks are included in the fee. The coffee breaks on Monday are sponsored by:<br />
Cloakroom facilities<br />
A paid cloakroom is situated at the Forum Lounge, near the registration desk. The<br />
cloakroom will be guarded during Congress hours. The organizers cannot accept liability<br />
for loss or damage to property.<br />
Currency and banking<br />
The local currency is the euro (Eur/€). € 1 = 100 cents. Visa, MasterCard and<br />
American Express are accepted at the Registration Desk. Foreign currency will not be<br />
accepted. You are requested to pay with credit card or cash in Euros only. In general,<br />
all major credit cards are accepted for payment in hotels, restaurants and shops.<br />
There is an ATM machine in the RAI Convention Center, accessible via the entrance K2<br />
(exit the Auditorium Center, keep to the left and walk up to the corner, turn left; the<br />
first entrance is K2. Please ask the receptionist for further directions). There is also<br />
an ATM machine in the square opposite the RAI (ABN AMRO Bank, Scheldeplein 1-5).<br />
Banks are open Monday to Friday from 10.00 - 16.00 hrs.<br />
Disclaimer<br />
All best endeavours will be made to present the program as printed. However, the<br />
organizers reserve the right to alter or cancel, without prior notice, any arrangements,<br />
timetables, plans or other items relating directly or indirectly to the Congress for any<br />
cause beyond it’s reasonable control. In registering for the 7th HUPO Annual World<br />
Congress you agree that neither the organizing committee nor the congress secretariat<br />
accept any liability whatsoever. The organizers accept no liability for personal injuries<br />
or loss, of any nature whatsoever, or for loss or damage to property either during or<br />
as a result of the Congress. Participation is completely at the delegate’s own risk.<br />
The organizers will not be liable and will not compensate for any damage incurred to<br />
delegates during the Congress. Dutch laws apply. Delegates are advised to acquire<br />
their own travel insurance and to extend their policy to cover personal possessions<br />
160 161
as the Congress does not cover individuals against cancellation or bookings or theft<br />
or damage to belongings.<br />
Dress code<br />
Recommended dress code for the Congress and all social functions is smart casual.<br />
Electricity supply<br />
Electricity in the Netherlands is supplied at 220V - 50Hz AC. USA, English and some<br />
other foreign appliances require an adapter for the voltage as well as an adapter for<br />
the plug. There are no adapters available at the RAI Convention Centre.<br />
Emergencies<br />
If you or any other delegate is unwell, an accident or any other emergency occurs,<br />
while at the Amsterdam RAI Convention Centre, please contact the registration desk<br />
or any staff member.<br />
Internet Corner sponsored by WATERS:<br />
An Internet corner is at the disposal of the Congress delegates during Congress<br />
opening hours. Wireless internet will also be provided free of charge in this area. No<br />
access code required. Just select the HUPO 2008 network.<br />
Language<br />
The official congress language will be English. No translation arrangements will be made.<br />
Lost Property<br />
If you see any unattended parcel, please report to one of the Congress staff members.<br />
Should you loose anything at the Amsterdam RAI Convention Centre, please enquire<br />
at the Registration Desk.<br />
Lunches<br />
Lunch can be bought in the exhibition hall 10 or at Beach South.<br />
Messages<br />
Messages for delegates should be handed in at the Registration Desk. Notification<br />
of messages will be displayed on the message board next to the Registration Desk.<br />
Please check the board daily and pick up your messages – they may be urgent.<br />
Mobile phones<br />
Mobile phones must be switched off in the meeting rooms.<br />
Name badges and tickets<br />
For security purposes, delegates and exhibitors must wear their name badges at all<br />
times during the Congress. Entrance to the Amsterdam RAI Convention Centre will be<br />
limited to badge holders only. Replacement of lost name badges can be requested at the<br />
registration desk (costs € 25). Tickets for social <strong>event</strong>s and excursions will be issued to<br />
delegates who have booked for these <strong>event</strong>s. Please present your tickets at these <strong>event</strong>s<br />
and excursions.<br />
Orange Student Brigade<br />
A team of enthusiastic students will be at your service. During Congress hours, they<br />
will provide hospitality support and steward services. They will also serve in most<br />
of the meeting rooms as technical assistants and can be easily recognized by their<br />
orange shirts.<br />
Program changes<br />
The organizers cannot accept liability for any changes in the program due to external<br />
or unforeseen circumstances.<br />
Public Transport<br />
Amsterdam is a very compact city where your destination usually will not be at a great<br />
distance. Therefore, Amsterdam is ideal for getting around by foot, bicycle or public<br />
transport. There is a dense public transport system and tram, metro or bus stops<br />
are usually around the corner. Cars are less suitable for navigating in Amsterdam.<br />
Moreover, parking must be paid for in almost the entire city and the rates can be<br />
substantial.<br />
How to reach the Amsterdam RAI Convention Center:<br />
From Amsterdam RAI railway Station: from this station it is a short walk (8<br />
minutes) to the Convention Center. You can also take tram 4; first stop in front of<br />
the Convention Center.<br />
From the Central railway Station: tram 4<br />
From the Amstel railway Station: bus no. 15 or 62 to the Amsterdam RAI railway<br />
Station.<br />
There will be no shuttle service available between Schiphol Amsterdam International<br />
Airport, the Amsterdam RAI or the Congress hotels.<br />
Registration and Information:<br />
The registration desk will be located at the ground floor of the Forum Center<br />
(Entrance E of The Rai Convention Center).<br />
Opening hours:<br />
Saturday 16 <strong>August</strong><br />
Sunday 17 <strong>August</strong><br />
Monday 18 <strong>August</strong><br />
<strong>Tuesday</strong> <strong>19</strong> <strong>August</strong><br />
Wednesday 20 <strong>August</strong><br />
09.00 - <strong>19</strong>.00 hrs<br />
08.30 - 18.00 hrs<br />
07.30 - 18.00 hrs*<br />
07.30 - 20.00 hrs*<br />
07.30 - 18.30 hrs*<br />
* For Corporate Workshops registration from 06.30 hrs.<br />
Registered participants and students are entitled to:<br />
Opening ceremony and welcome reception<br />
Attendance to scientific sessions<br />
Entrance to the exhibition<br />
All congress documents<br />
Coffee and tea during the breaks<br />
162 163
Registered accompanying persons are entitled to:<br />
Opening ceremony and welcome reception<br />
Amsterdam city tour<br />
Services for the Disabled<br />
All the rooms at the Congress venue are fully accessible to delegates with<br />
disabilities.<br />
Smoking Policy<br />
In the RAI Convention Centre, smoking is prohibited by law. Smoking is only permitted<br />
in a few designated areas outside the building.<br />
Shopping<br />
Most shops are open from <strong>Tuesday</strong> through Friday from 9.00 to 18.00 hours, Saturdays<br />
from 09.00 to 17.00 hours. On Mondays, many shops are closed in the morning. They<br />
open between 11.00 and 13.00 hours and close at 18.00 hours. Evening shopping<br />
(until 21.00 hours) is on Thursdays and many shops in the city centre open on Sundays<br />
from 12.00 to 17.00 hours.<br />
Time<br />
Amsterdam is 1 hour ahead of Greenwich Mean Time.<br />
Tipping<br />
Service is always included. However, it is customary to tip in restaurants and when<br />
paying for taxi’s. As a general rule tipping between 5 - 10% should be adequate.<br />
Taxis<br />
Taxis can be ordered at the Porter’s Desk in the access hall of the Auditorium.<br />
Social Program<br />
opening ceremony & welcome reception<br />
Date:<br />
Time:<br />
Location:<br />
Dress code:<br />
Price:<br />
Monday 18 <strong>August</strong><br />
16:00 - <strong>19</strong>:00 hrs<br />
Amsterdam RAI Convention Centre, Auditorium & Exhibition Area<br />
Smart casual<br />
included in the registration fee for registered participants and<br />
registered accompanying persons.<br />
The Opening Ceremony will be held in the Auditorium and opened by eminent<br />
representatives of the international scientific community. Don’t miss this opportunity<br />
to enjoy this mix of Dutch and international cultural outings! The Opening Ceremony will<br />
be followed by the welcome reception.<br />
A welcome reception will be offered to delegates and registered accompanying persons<br />
at the Exhibition area. Just enjoy each other’s company and mingle while enjoying<br />
typical Dutch snacks and entertainment. All participants are invited to attend this<br />
reception of the 7th Annual HUPO Congress so bring your (registered) family and<br />
friends and have a good start of the congress!<br />
congress dinner<br />
Date:<br />
Wednesday 20 <strong>August</strong><br />
Time:<br />
<strong>19</strong>:00 - 23:00 hrs<br />
Location: Stopera (acronym for “Stadhuis”=City Hall and the “Opera”=Theatre)<br />
Departure: By canal boat from RAI Harbour at 18.15 hrs.<br />
Dress code: Smart casual<br />
Price: €65,00<br />
We would like to invite all participants to attend the 7th Annual HUPO Congress<br />
Dinner. Join us and all the other delegates from around the world on this splendid,<br />
colorful evening in the heart of Amsterdam. The Stopera is beautifully located right<br />
on the Amstel river, and the high open foyers overlook the historic panorama of<br />
Amsterdam.<br />
164 165
Accompanying Persons<br />
Tour / Excursion *<br />
(included in the Accompanying Person’s fee)<br />
This tour includes a most panoramic drive through the centre and the modern suburbs,<br />
passing the most important monuments and sights including a stop at the Rembrandt<br />
windmill. The excursion will end with a canal cruise through the city of Amsterdam and<br />
to admire the famous 17th century merchant houses with its different gable structures<br />
and the numerous bridges which makes Amsterdam ‘The Venice of the North’.<br />
Date: Monday 18 <strong>August</strong><br />
Time: 12:30 - 15:30 hrs<br />
Rate: €35,00 per person<br />
Amsterdam city tour<br />
Tours should have been booked in advance when registering for the congress<br />
Registration and cancellation conditions are applied to the tours and excursions.<br />
The cost of tickets cannot be refunded if you do not take part or have not taken<br />
part in the tour / excursion.<br />
* Due to an insufficient number of registrations, the following tours had to be cancelled: Aalsmeer, Delft &<br />
the Hague; Rotterdam and Kinderdijk Windmills; Zaanse Schans; Castles & River Vecht. If you have already<br />
registered for one of those, you are most welcome to join the other tour. Pease contact the Registration Desk<br />
for more information.<br />
Exhibitor and Sponsor Listing<br />
Abfrontier Co. Ltd<br />
Stand: 070<br />
Korea<br />
Website: www.abfrontier.com<br />
Agilent Technologies<br />
Stand: 032<br />
Website: www.agilent.com/chem<br />
American Chemical Society<br />
Stand: 027<br />
USA<br />
Website: http://pubs.acs.org<br />
Applied Biosystems / MDS Analytical Technologies<br />
Stand: 063<br />
USA<br />
Website: www.appliedbiosystems.com<br />
Atlas Antibodies<br />
Stand: 025<br />
Sweden<br />
Website: www.atlasantibodies.com<br />
A Publication of the American Chemical Society<br />
Aushon BioSystems<br />
Stand: 115<br />
USA<br />
Website: www.aushon.com<br />
Australian Proteome Analysis Facility Ltd<br />
Stand: 008<br />
Australia<br />
Website: www.proteome.org.au<br />
APAF<br />
australian proteome<br />
anaylsis facility<br />
Axela Inc.<br />
Stand: 104<br />
Canada<br />
Website: www.axela.com<br />
166 167
BD Biosciences<br />
Stand: 082<br />
Belgium<br />
Website: www.bdbiosciences.com<br />
BD Diagnostics<br />
Stand: 080<br />
Germany<br />
Website: www.bd.com<br />
Bio-Rad Laboratories<br />
Stand: 090<br />
USA<br />
Website: www.bio-rad.com<br />
Bruker Daltonics<br />
Stand: 022<br />
Germany<br />
Website: www.bdal.de<br />
Caprotec Bioanalytics GmbH<br />
Stand: 044<br />
Germany<br />
Website: www.caprotec.com<br />
Digilab Genomic Solutions (UK) Ltd<br />
Stand: 023<br />
UK<br />
Website: www.genomicsolutions.com<br />
Dionex Corporation<br />
Stand: 061<br />
Switzerland<br />
Website: www.dionex.com<br />
Dualsystems Biotech AG<br />
Stand: 073<br />
Switzerland<br />
Website: www.dualsystems.com<br />
Eksigent Technologies<br />
Stand: 084<br />
USA<br />
Website: www.eksigent.com<br />
Elsevier<br />
Stand: 078<br />
The Netherlands<br />
Website: www.elsevier.com<br />
GENOMIC SOLUTIONS<br />
CovalX AG<br />
Stand: 083<br />
Switzerland<br />
Website: www.covalx.com<br />
CTMM<br />
The Netherlands<br />
Website: www.ctmm.nl<br />
Decodon<br />
Stand: 101<br />
Germany<br />
Website: www.decodon.com<br />
Denator AB<br />
Stand: 072<br />
Sweden<br />
Website: www.denator.com<br />
C OVAL X<br />
Solutions for Protein Complex Analysis<br />
EMBL-European Bioinformatics Institute<br />
Stand: 047<br />
UK<br />
Website: www.ebi.ac.uk<br />
Epitomics, Inc.<br />
Stand: 046<br />
USA<br />
Website: www.epitomics.com<br />
EuPA / The Swedish Academy of Pharmaceutical Sciences<br />
Stand: 074<br />
Website: www.eupa.org<br />
GE Healthcare Europe GmbH<br />
Stand: 052<br />
Germany<br />
Website: www.gelifesciences.com<br />
168 169
Genebio Geneva Bioinformatics<br />
Stand: 103<br />
Switzerland<br />
Website: www.genebio.com<br />
GenoLogics<br />
Stand: 100<br />
Canada<br />
Website: www.genologics.com<br />
GenWay Biotech, Inc.<br />
Stand: 012<br />
USA<br />
Website: www.genwaybio.com<br />
GL Sciences, Inc.<br />
Stand: 001<br />
Japan<br />
Website: www.gls.co.jp<br />
GenWay Biotech, Inc.<br />
Protein and Antibody Solutions<br />
Integrated Analysis, Inc.<br />
USA<br />
Website: www.i-a-inc.com<br />
Invitrogen / Dynal<br />
Stand: 108<br />
Scotland, UK<br />
Website: www.invitrogen.com<br />
IOS Press<br />
Stand: 105<br />
The Netherlands<br />
Website: www.iospress.nl<br />
JPT Peptide Technologies GmbH<br />
Stand: 003<br />
Germany<br />
Website: www.jpt.com<br />
Hoefer, Inc.<br />
Stand: 102<br />
USA<br />
Website: www.hoeferinc.com<br />
HUPO 2009<br />
Stand: 075<br />
Website: www.hupo2009.com<br />
HUPO 2010<br />
Australia<br />
Website: www.hupo2010.com<br />
Labcyte, Inc.<br />
Stand: 110<br />
USA<br />
Website: www.labcyte.com<br />
Ludesi AB<br />
Stand: 087<br />
Sweden<br />
Website: www.ludesi.com<br />
Merck & Co., Inc.<br />
USA<br />
Website: www.merck.com<br />
TM<br />
HUPO HQ<br />
Stand: 076<br />
Canada<br />
Website: www.hupo.org<br />
INTAVIS Bioanalytical Instruments<br />
Stand: 002<br />
Germany<br />
Website: www.intavis.com<br />
Merck/EMD, Novagen & Calbiochem<br />
Stand: 107<br />
USA<br />
Website: www.emdchemicals.com<br />
Miltenyi Biotec<br />
Stand: 030<br />
Germany<br />
Website: www.miltenyibiotec.com<br />
170 171
Nanoxis AB<br />
Stand: 051<br />
Sweden<br />
Website: www.nanoxis.com<br />
Netherlands Genomics Initiative / Netherlands Proteomics Centre<br />
Stand: 009<br />
The Netherlands<br />
Website: www.genomics.nl / www.netherlandsproteomicscentre.nl<br />
Nonlinear Dynamics<br />
Stand: 037<br />
UK<br />
Website: www.nonlinear.com<br />
Pall Life Sciences<br />
Stand: 011<br />
UK<br />
Website: www.pall.com<br />
Peaks<br />
Stand: 031<br />
Canada<br />
Website: www.bioinfor.com<br />
PSS Europe GmbH<br />
Stand: 045<br />
Germany<br />
Website: www.pss-europe.de<br />
Pressure BioSciences, Inc.<br />
Stand: 118<br />
USA<br />
Website: www.pressurebiosciences.com<br />
Proteored<br />
Spain<br />
Website: www.proteored.org<br />
Proxeon<br />
Stand: 004<br />
Denmark<br />
Website: www.proxeon.com<br />
Qiagen<br />
Stand: 071<br />
UK<br />
Website: www.qiagen.com<br />
RSC Publishing<br />
Stand: 111<br />
UK<br />
Website: www.rsc.org<br />
R&D Systems Europe Ltd<br />
Stand: 066<br />
UK<br />
Website: www.rndsystems.com<br />
Rosetta Bio<strong>software</strong><br />
Stand: 085<br />
USA<br />
Website: www.rosettabio.com<br />
Science International / AAAS<br />
Stand: 079<br />
UK<br />
Website: www.science-int.co.uk<br />
national institutefor proteomics<br />
Promega Corporation<br />
Stand: 042<br />
USA<br />
Website: www.promega.com<br />
Protein Forest, Inc.<br />
Stand: 086<br />
USA<br />
Website: www.proteinforest.com<br />
SERVA Electrophoresis GmbH / Bridge4Bio<br />
Stand: 068<br />
Germany<br />
Website: www.serva.de<br />
Shimadzu Europe GmbH<br />
Stand: 092<br />
Germany<br />
Website: www.shimadzu.eu<br />
172 173
Sigma-Aldrich<br />
Stand: 026<br />
USA<br />
Website: www.sigma-aldrich.com<br />
Silantes GmbH<br />
Stand: 005<br />
Germany<br />
Website: www.silantes.com<br />
Syngene<br />
Stand: 040<br />
UK<br />
Website: www.syngene.com<br />
Thermo Scientific<br />
Stand: 034<br />
UK<br />
Website: www.thermo.com<br />
UVic Genome BC Proteomics Centre<br />
Stand: 006<br />
Canada<br />
Website: www.proteincentre.com<br />
UVP<br />
Stand: 007<br />
UK<br />
Website: www.uvp.com<br />
Wiley-VCH Verlag<br />
Stand: 1<strong>19</strong><br />
Germany<br />
Website: www.wiley-vch.de<br />
Waters<br />
Stand: 060<br />
France<br />
Website: www.waters.com<br />
UVic Genome BC<br />
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See these industry-leading targeted quantitative proteomics solutions in booth #63.<br />
• 4000 QTRAP ® LC/MS/MS System —The only system to provide MRM quantitation<br />
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• MultiQuant Software—Easy-to-use <strong>software</strong> optimized for high throughput<br />
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• Scheduled MRM Algorithm—Maximizing MRM dwell times for more robust<br />
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BOOTH #63<br />
Applera, Applied Biosystems and AB (Design) are registered trademarks of Applera Corporation or its subsidiaries in the US and/or certain other countries. QTRAP is a registered trademark and mTRAQ, MRMPilot, Scheduled MRM<br />
and MultiQuant are trademarks of Applied Biosystems/MDS Analytical Technologies, a joint venture of Applera Corporation and MDS Inc. MDS Analytical Technologies is a trademark of MDS Inc.<br />
© 2008 Applera Corporation and MDS Inc. Joint Owners. All rights reserved.<br />
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16<br />
7<br />
6 14<br />
8<br />
2<br />
5<br />
4<br />
11<br />
21<br />
<strong>19</strong><br />
10<br />
9<br />
18<br />
20<br />
23 3<br />
1<br />
22<br />
17<br />
12<br />
13<br />
15<br />
Hotel Map<br />
Nr. Hotel Nr. Hotel<br />
1 Hotel Okura Amsterdam 12 Mercure Amsterdam a/d Amstel<br />
2 NH Barbizon Palace 13 Holiday Inn<br />
3 Hilton Amsterdam 14 Park Plaza Victoria Amsterdam<br />
4 NH City Centre 15 Novotel Amsterdam<br />
5 NH Grand Hotel Krasnapolsky 16 Ibis Amsterdam Centre<br />
6 Crowne Plaza Amsterdam City Centre 17 Artemis Amsterdam<br />
7 Renaissance Amsterdam Hotel 18 Vondel Park Plaza<br />
8 Sofitel Amsterdam <strong>19</strong> Eden Hotel Amsterdam<br />
9 Park Hotel 20 Trianon Hotel<br />
10 Eden Rembrandt Square 21 Amstel Botel<br />
11 Mövenpick Hotel Amsterdam City 22 Hotel Casa 400<br />
23 Bilderberg Garden Hotel Amsterdam<br />
176