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Radiation Protection for Radiotherapy - E. Aird (ESTRO) - European ...

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<strong>ESTRO</strong> Activities: <strong>Radiation</strong><br />

<strong>Protection</strong> <strong>for</strong> <strong>Radiotherapy</strong><br />

Edwin <strong>Aird</strong><br />

RPA/<strong>ESTRO</strong> Teacher


<strong>ESTRO</strong> Mission ( education)<br />

• The <strong>ESTRO</strong> School of <strong>Radiotherapy</strong> and<br />

Oncology is an international school that aims to<br />

improve, professionalise and standardise<br />

knowledge and practice in radiation oncology<br />

and associated professions in Europe and<br />

beyond. Our guiding principles are set out in our<br />

mission statement which was approved by the<br />

<strong>ESTRO</strong> Board on 14th September, 2008<br />

• To organise courses; workshops; large scientific<br />

meetings (all professions and researchers)<br />

together with the manufacturers.


801<br />

958<br />

1199<br />

1149<br />

1138<br />

1434<br />

1826<br />

1976<br />

2611<br />

2745<br />

2836<br />

2843<br />

Recent <strong>ESTRO</strong> Activity<br />

NUMBER OF COURSES AND PARTICIPANTS<br />

2000-2011<br />

Courses<br />

Participants<br />

1<br />

0<br />

1<br />

3<br />

1<br />

2<br />

1<br />

1<br />

1<br />

2<br />

1<br />

4<br />

1<br />

6<br />

1<br />

9<br />

2<br />

3<br />

2<br />

8<br />

3<br />

0<br />

3<br />

1<br />

2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011


<strong>ESTRO</strong> LIVE COURSES:<br />

ROADMAP


Aim of <strong>Radiotherapy</strong> (and the meaning of<br />

radiation protection in <strong>Radiotherapy</strong>)<br />

• To sterilise the tumour (e.g 74Gy)with<br />

minimum damage to the surrounding<br />

normal tissues and critical structures<br />

• Best practice requires: optimal planning in<br />

3D on CT; dose prescription includes<br />

dose/fraction and overall time AND critical<br />

structure tolerances (dose/volume criteria);<br />

full reporting of all these factors (ICRU 50<br />

ICRU 62; ICRU ## etc)


TISSUE EFFECTS FOR<br />

RADIOTHERAPY: Tumour Control<br />

Probability can increase without<br />

increasing NTCP if CTV-PTV<br />

margins are reduced<br />

Dose<br />

Escalation<br />

Moves to the<br />

right as<br />

margin<br />

reduced


ICRU volumes<br />

<strong>for</strong> Breast<br />

Internal Target<br />

Volume


<strong>Radiotherapy</strong> Process<br />

• Pre-planning diagnostic images<br />

• Planning Images: CT/MRI/PET/US etc<br />

• Transfer of 3D Patient Image to Treatment<br />

Planning System<br />

• Planning: 3D Con<strong>for</strong>mal; IMRT etc<br />

• Transfer actual patient to linac (or other) and<br />

correctly and accurately position<br />

• Verification Radiographs/CBCT<br />

• Treat/Follow-up


General Knowledge <strong>for</strong> R/T<br />

• Physics of the atom<br />

• Sources: High Energy 6-20MV + Diagnostic; Sealed and<br />

unsealed sources (e.g. Ir-192; I-125; I-131)<br />

• <strong>Radiation</strong> Physics<br />

– Interaction; geometry of beams etc<br />

• Radiobiology<br />

– Time/dose/fractionation; models etc<br />

• Concomitant Imaging <strong>for</strong> <strong>Radiotherapy</strong> ([For Image<br />

Guided <strong>Radiotherapy</strong> (IGRT)]<br />

• Second Cancer: imaging doses and out-of-beam doses<br />

• <strong>Protection</strong> Legislation


Modern Linac with the addition of kV<br />

On-Board-Imaging (Includes CBCT)


100000<br />

Dose in<br />

mGy<br />

10000<br />

Rectum<br />

Bone-<br />

Marrow<br />

R/T doses (mGy)<br />

<strong>for</strong> Prostate 74Gy<br />

(15MV) vs distance<br />

ALLEGRO<br />

EU Project<br />

1000<br />

100<br />

Colon<br />

Stomach<br />

Lung<br />

CT doses<br />

<strong>for</strong> daily<br />

CBCT<br />

R/T<br />

C/T<br />

Liver<br />

10<br />

Thyroid<br />

1<br />

0 20 40 60 80<br />

Distance<br />

Distance cm<br />

from centre<br />

from of fields centre


<strong>ESTRO</strong> and <strong>European</strong> Curricula<br />

<strong>European</strong> Core Curricula have been developed <strong>for</strong> the training<br />

of medical specialists in radiotherapy (radiation oncology),<br />

medical physicists in the field of radiotherapy<br />

and radiotherapy technologists.<br />

In 2002, these were endorsed by representatives<br />

from 35 <strong>European</strong> countries. In 2008 the school was created<br />

to bring together the established teaching<br />

Courses into a coherent structure. In 2011 the 3 Core Curricula<br />

have been updated


Basic Science <strong>for</strong> Oncologists (Part of<br />

<strong>ESTRO</strong> Core Curricula)<br />

• Radiobiology:<br />

– Describes the interaction of radiation on molecular<br />

level (knowledge)<br />

– Discusses DNA damage (comprehension)<br />

– Describes cellular effects, mechanisms of cell death<br />

(knowledge)<br />

– Describes repair of radiation damage (knowledge)<br />

– Discusses cell survival curves (comprehension)<br />

– Describes normal tissue systems (knowledge)


Basic Sciences (oncologists)<br />

• Basic radiation physics<br />

– Describes atomic and nuclear structure<br />

(knowledge)<br />

– Describes radioactive decay (knowledge)<br />

– Contrasts the properties of particle and<br />

electromagnetic radiation (analysis)<br />

– Defines and describes radioisotopes<br />

(knowledge)


Eg Part of <strong>ESTRO</strong> Training Course<br />

• Physics of teletherapy beams:<br />

– Energy of X-ray beams<br />

– Build-up and skin sparing<br />

– PDD and Isodose curves<br />

– Principles of wedges<br />

– Output factors<br />

– Beam geometry/penumbra etc


Isodoses<br />

• Depth dose penetrates further<br />

into tissue through thin end<br />

• Dynamic wedges give “pointier”<br />

isodoses<br />

• Slope reduces with depth due to<br />

scatter<br />

• Used in oblique incidence to<br />

shift isodoses by angle of<br />

incidence


Wedged pair<br />

• For head region<br />

• e.g. maxillary antrum or floor of the mouth<br />

• [NB What about Monitor Units?]


Treating the prostate ( 74Gy in 2Gy per#); avoiding rectum, bladder, etc


Isodose display - can be<br />

complex and 3D


Prostate Intensity Modulated RT plan,<br />

showing some reduction of rectal wall dose


Basic Sciences (oncologists)<br />

• Radioprotection<br />

– Discusses the general philosophy of radioprotection including<br />

ALARA (comprehension)<br />

– Contrasts stochastic and deterministic effects (analysis)<br />

– Discusses the risk of induction of secondary tumours<br />

(comprehension)<br />

– Defines and discusses radiation weighting factor (knowledge)<br />

– Defines and discusses equivalent dose – tissue weighting factor<br />

(comprehension)<br />

– Discusses occupational/public health consequences of radiation<br />

exposure, radioprotection and dose<br />

– limits <strong>for</strong> occupational and public exposure (comprehension)<br />

– Outlines <strong>European</strong> and national legislation (knowledge)<br />

– Determines what is evidence based in radioprotection<br />

(knowledge


Cyberknife<br />

Robotic<br />

<strong>Radiotherapy</strong><br />

using 6MV x-<br />

rays<br />

<strong>ESTRO</strong> Physics 2007<br />

<strong>ESTRO</strong> Physics 2007


Aspects of <strong>Radiation</strong> protection <strong>for</strong><br />

<strong>Radiotherapy</strong><br />

• Room Design; staff protection only <strong>for</strong><br />

sealed and unsealed sources<br />

• Second Cancer<br />

• Quality Assurance:<br />

– Definitions: QA, QC , QM, QS<br />

– Verification<br />

– Reporting Near misses and errors<br />

– What’s in a prescription…link to legislation


<strong>ESTRO</strong> Ref<br />

• The updated <strong>ESTRO</strong> core curricula 2011 <strong>for</strong> clinicians, medical<br />

physicists and RTTs in radiotherapy/radiation oncology JG Eriksen<br />

et al <strong>Radiotherapy</strong> & Oncology 103, 103-108 (2012)<br />

• Competencies in radiation oncology: A new approach <strong>for</strong> education<br />

and training of professionals <strong>for</strong> radiiotherapy and oncology in<br />

Europe R Potter et al <strong>Radiotherapy</strong> & Oncology 103, 1-4 (2012)<br />

• Shaping the future; training of professionals <strong>for</strong> radiotherapy in<br />

Europe M Baumann et al <strong>Radiotherapy</strong> & Oncology 70, 103 (2004)<br />

• Guidelines <strong>for</strong> the infrastructure of training institutes and teaching<br />

departments <strong>for</strong> radiotherapy in Europe E Rottinger et al Radio &<br />

Oncol 70, 123 (2004)


<strong>ESTRO</strong><br />

• <strong>ESTRO</strong> e-learning: EAGLE: <strong>ESTRO</strong><br />

Application <strong>for</strong> Global Learning<br />

• <strong>ESTRO</strong> web education:<br />

• http://www.estro-education.org


<strong>Protection</strong> <strong>for</strong> Brachy HDR<br />

• Well designed room ( which includes antiterrorist<br />

measures) +room GM tube<br />

• Calibration of new source (well chamber)<br />

• Emergency procedures ( especially if<br />

source sticks in patient)<br />

• Security (Environment Agency/Anti-Terror)<br />

• Quality Assurance: daily checks


HDR room design (example)


Layout example


<strong>Radiation</strong> <strong>Protection</strong> (<strong>ESTRO</strong> Physicists)<br />

– They have to be prepared to address the needs of<br />

protecting the patient, personnel and the general<br />

public in the radiotherapy department.<br />

– They have to know the physical and biological effects<br />

of radiation <strong>for</strong> exposed individuals, the relevant<br />

regulations, methods of compliance and record<br />

keeping.<br />

– This knowledge will allow them to assess the<br />

radiation risk and optimise the medical exposures.<br />

– They will be asked to apply the ALARA and dose<br />

limitation principles in the design of radiation therapy<br />

facilities, treatment and imaging protocols.


<strong>Radiation</strong> <strong>Protection</strong> <strong>for</strong> Physicists<br />

• Competences<br />

• • demonstrate an understanding of the principles of radiation safety procedures;<br />

• • ability to measure effective per<strong>for</strong>mance of radiation safety procedures;<br />

• • ability to improve effective per<strong>for</strong>mance of radiation safety procedures;<br />

• • ability to investigate and assess risk factors of radiation;<br />

• • ability to optimise medical exposures;<br />

• • ability to verify that the clinical physics program is in compliance with applicable<br />

national radiation safety regulations (e.g., radioactive materials licenses, occupational<br />

dose limits, and review of radiation surveys <strong>for</strong> any new construction);<br />

• • ability to per<strong>for</strong>m radiation surveys of an area using appropriate dose-rate meters<br />

• • ability to per<strong>for</strong>m design calculations <strong>for</strong> a linac room, simulator/CT room,<br />

brachytherapy source room;<br />

• • ability to discuss the use of personal dosimeters;<br />

• • ability to prepare the documentation needed <strong>for</strong> audits by the radiation protection<br />

authorities;


Basic Sciences (oncologists)<br />

• <strong>Radiation</strong> physics applied in radiation therapy (RT)<br />

• Outlines the design and explains the mechanism of action of an X-<br />

ray tube (comprehension)<br />

• Describes the design and explains the mechanism of action of a<br />

linear accelerators<br />

• (comprehension)<br />

• Describes specialized collimating systems (knowledge)<br />

• Describes brachytherapy systems (knowledge)<br />

• Outlines the design and explains the mechanism of action of a<br />

cyclotron (comprehension)<br />

• Defines, explains and discusses absorbed dose distributions<br />

(comprehension)<br />

• Describes treatment planning including 3D planning, virtual and CT<br />

simulation and applies these<br />

• procedures to plan patients’ treatments (application

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