Dr Tom Roques, Norfolk & Norwich University Hospital

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09/01/2013 PET to improve concordance Steenbakkers et al. IJROBP 2008 Radiochemotherapy +/- tirapazamine in HN cancer 861 patients, 82 centres in 16 countries Diagnostic imaging and plans submitted for central review by end of week 1 of therapy (n=687). Changes recommended in 197 (29%) 14
09/01/2013 QA review of all plans within trial Further TMC review after trial closed of all evaluable patients (n=820) 97 major errors - 24 incorrect GTV, 41 PTV not covered, 25 incorrect prescription, 7 prolonged treatment 197 plans had major changes recommended during the study Of these 89 were implemented - all passed TMC review 108 not implemented - 95 failed TMC review 15
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Page 9 and 10: 09/01/2013 Huge variation in the UK
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Page 21: 09/01/2013 Conclusions • Take lea

Dr Tom Roques, Norfolk & Norwich University Hospital

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