Trends und Probleme aus der Praxis - GV-Solas

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Goals Anesthesia – species-specific problems in mouse anesthesia – types of anesthesia • injection anesthesia • inhalation anesthesia ‣examples, problems ‣optimized protocols Pain therapy – decide on pain therapy – drugs, side effects – dosages ‣intensive post-operative care in mice
Species-specific problems in mouse anesthesia the mouse – 18 – 50 g body weight – hypothermia – access to arteries, veins – injection side the drugs – feasibility Propofol ® , diazepam, di-ethyl-ether, … – availability InnovarVet ® > off the market Hypnorm ® > narcotics laws, import from UK – i.p., s.c. Halothane > off the market? monitoring Metofane ® > import from Australia blood pressure heart rate, ECG – regulations for protection of the personnel secure gas scavenging pulsoximetry blood gases and acid base balance – legal restrictions from welfare concerns Avertin ® , di-ethyl-ether, … – intervention cardiac arrest respiratory depression
Page 1: Bundesinstitut für Risikobewertung
Page 5 and 6: Avertin ® Tribromoethanol Zeller,
Page 7 and 8: Injection anesthesia Combination of
Page 9 and 10: Sensitivity to injectable anestheti
Page 11 and 12: Time of surgical tolerance and immo
Page 13 and 14: example Improved ketamin xylazine a
Page 15 and 16: example Short intraperitoneal injec
Page 17 and 18: Isoflurane: long-term exposition of
Page 19 and 20: pressure reducing valve flow meter
Page 21 and 22: How to decide on pain therapy exper
Page 23 and 24: Trends in rodent pain therapy Table
Page 25 and 26: Intensive care in mice after major
Page 27 and 28: Fluid therapy Ringer-Lactat or NaCl

Trends und Probleme aus der Praxis - GV-Solas

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