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Introduction to CV Pharmacology - Orlando Health

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<strong>CV</strong> <strong>Pharmacology</strong><br />

systemic vasoconstriction and a decreased blood pressure.<br />

Indications<br />

ARBs are indicated for the treatment and management of mild <strong>to</strong> severe hypertension. Used in<br />

patients with heart failure because they block the vasoconstrictive effects of angiotension-II and<br />

the release of aldosterone.<br />

Precautions<br />

Angiotensin recep<strong>to</strong>r antagonists may cause hypotension or symp<strong>to</strong>ms related <strong>to</strong><br />

hypotension.<br />

In some patients, the use of ARB therapy may result in transient increases in BUN and<br />

creatinine.<br />

© 2010 <strong>Orlando</strong> <strong>Health</strong>, Education & Development 27

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