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Clinical Guidelines for the use of Palliative Care Drugs in Renal ...

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<strong>Cl<strong>in</strong>ical</strong> <strong>Guidel<strong>in</strong>es</strong> <strong>for</strong> In<strong>for</strong>mation is from <strong>in</strong>dividual data sheets, except, <strong>in</strong> blue = <strong>Renal</strong> Drug Handbook 2 nd<br />

PALLIATIVE CARE DRUGS IN RENAL FAILURE Edition, and <strong>in</strong> green = Micromedex. All o<strong>the</strong>r references are specified.<br />

DRUG<br />

Enoxapar<strong>in</strong><br />

METABOLITES<br />

(A=active,<br />

I=<strong>in</strong>active)<br />

ELIMINATION<br />

(D=drug,<br />

M=metabolites)<br />

Erythromyc<strong>in</strong> Biliary(D)<br />

Fentanyl Norfentalyl (I) D – 9% faecal<br />

D,M - 75% renal<br />

Flucloxacill<strong>in</strong> <strong>Renal</strong> (D)<br />

Fluconazole<br />

Fluoxet<strong>in</strong>e<br />

1,2,3-triazole and<br />

o<strong>the</strong>rs (liver – poor<br />

metab)<br />

Norfluoxet<strong>in</strong>e (A)<br />

(and o<strong>the</strong>r<br />

unidentified M)<br />

<strong>Renal</strong> D,M<br />

(approx. 80%<br />

unchanged)<br />

Ur<strong>in</strong>e

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