Clinical Guidelines for the use of Palliative Care Drugs in Renal ...
Clinical Guidelines for the use of Palliative Care Drugs in Renal ...
Clinical Guidelines for the use of Palliative Care Drugs in Renal ...
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<strong>Cl<strong>in</strong>ical</strong> <strong>Guidel<strong>in</strong>es</strong> <strong>for</strong> In<strong>for</strong>mation is from <strong>in</strong>dividual data sheets, except, <strong>in</strong> blue = <strong>Renal</strong> Drug Handbook 2 nd<br />
PALLIATIVE CARE DRUGS IN RENAL FAILURE Edition, <strong>in</strong> p<strong>in</strong>k = <strong>Renal</strong> Drug Handbook – Draft 3 rd edition and <strong>in</strong> green = Micromedex.<br />
All o<strong>the</strong>r references are specified.<br />
DRUG<br />
Ibupr<strong>of</strong>en<br />
Ketam<strong>in</strong>e<br />
Ketorolac<br />
Lactulose<br />
METABOLITES<br />
(A=active,<br />
I=<strong>in</strong>active)<br />
Liver metabolism to<br />
<strong>in</strong>active conjugates (I)<br />
Nor-ketam<strong>in</strong>e (A)<br />
dehydronor-ketam<strong>in</strong>e<br />
(I)<br />
Hydroxylated <strong>in</strong>to<br />
<strong>in</strong>active metabolite (I)<br />
Lactic acid (A)<br />
Formic acid (A)<br />
Acetic acid (A)<br />
ELIMINATION<br />
(D=drug,<br />
M=metabolites)<br />
<strong>Renal</strong><br />
D