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Chapter 22 <strong>Cannulae</strong><br />

<strong>Cannulae</strong><br />

The various cannulae used in surgery are important to the perfusionist.<br />

These cannulae link the perfusion circuit with the patient. The cannulae of the<br />

perfusion circuit include the arterial, venous, antegrade cardioplegia and<br />

retrograde cardioplegia. In addition, there are left ventricular vents, pulmonary<br />

artery vents and aortic root vents. Features of the cannulae are discussed in<br />

this section. These features should be considered when cannulae are chosen.<br />

The arterial and venous cannulae often create controversy. The<br />

perfusionist wants the largest possible cannula while the surgeon prefers to<br />

place the smallest possible cannula. The perfusionist requires a certain size<br />

cannula to achieve certain flows without exceeding pressure gradients. The<br />

surgeon must limit the size of the cannula if surgical considerations make it<br />

imperative.<br />

Arterial <strong>Cannulae</strong><br />

The arterial cannula used is determined by evaluating the flow and<br />

pressure drop charts. The pressure drop (the difference between the pressure<br />

entering the cannula and that leaving) shows resistance. The greater the<br />

pressure drop, the greater is the resistance. This is usually inversely related to<br />

the size of the cannula. With higher pressure across the cannula, there is an<br />

increase in jetting at the tip that can cause intimal damage to the aorta and<br />

hemolysis. The accepted limit of pressure drop is 100 mmHg. This should not<br />

ordinarily be exceeded. By examining the charts the manufacturer provides<br />

with the cannula, determination of maximum flow can be made. The charts<br />

found later in this chapter will list some of the <strong>com</strong>mon arterial cannulae used<br />

and their maximum flows.<br />

Venous <strong>Cannulae</strong><br />

Venous cannulae flows are by gravity drainage. The higher the<br />

pressure drop, the greater is the resistance to flow. Therefore, the lower the<br />

pressure drop, the better the flow is. The pressure drop is inversely related to<br />

size. Generally, the larger the venous cannula, the lower the pressure drop, and<br />

the better the flow is. The most <strong>com</strong>mon venous cannula used is the two stage<br />

cannula. It has an open tip that is placed in the inferior vena cava (IVC), and<br />

more proximal openings that will be located in the right atrium. This produces<br />

only partial bypass and may require venting of the heart to prevent distention.<br />

There are large single stage cannulae that may be placed in the right atrium.<br />

These do not always drain as well as a two stage, but are sometimes used when<br />

a two stage cannula will not go into the IVC. The other method of venous<br />

cannulation is with two single stage cannulae. One is placed in the superior<br />

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Chapter 22 The Manual of Clinical <strong>Perfusion</strong><br />

vena cava (SVC) and the other in the IVC. These are connected to a <strong>com</strong>mon<br />

venous line with a Y-connector. This type of cannulation also causes the<br />

effect of partial bypass as the two stage cannula does. That is some blood<br />

manages to go around the cannulae, through the heart and to the lungs. When<br />

the cannulae in the SVC and IVC have either a clamp or umbilical tape pulled<br />

around them, all blood <strong>com</strong>ing to the heart is diverted to the cannulae. This is<br />

termed total bypass. This manner of venous cannulation is most often used in<br />

valvular or congenital surgery. A venous cannulae chart will be listed later in<br />

this chapter. This chart suggests the cannulae used with certain weight<br />

categories.<br />

Cardioplegia <strong>Cannulae</strong><br />

The other cannulae used during bypass are specific to certain<br />

procedures. Retrograde cardioplegia is a popular technique of giving<br />

cardioplegia. The cannula is placed into the coronary sinus through the right<br />

atrium. The cannula has a balloon near its tip that when inflated prevents the<br />

flow of the cardioplegia back into the right atrium. The flow is, instead, forced<br />

backwards through the coronary veins, capillaries and arteries. The cannulae<br />

are of two basic types: either automatic or manual balloon inflation. Selection<br />

is surgeon preference.<br />

Antegrade cardioplegia is given through a cannula in the aortic root<br />

or directly into the coronary os. (When given directly into the os a coronary<br />

perfusion cannula is used.) These cannulae <strong>com</strong>e in various sizes and in different<br />

configurations. Basically, they have short needle tips that are placed into the<br />

aorta. Cardioplegia is then given into the root. The aortic valve and the aortic<br />

cross clamp prevent flow in either direction and thus force the cardioplegia<br />

into the coronary arteries. Some have an extra arm <strong>com</strong>ing off the side to allow<br />

a vent tubing to be connected and thus provide both functions in turn. The<br />

sizes of these cannulae affect the pressure drop and thus the maximum flow.<br />

Selection is surgeon preference.<br />

Coronary perfusion cannulae <strong>com</strong>e in different sizes and shapes. A<br />

<strong>com</strong>mon design is the small hand held cannula with a soft tip that is placed<br />

over the coronary os. Others have tips that engage the coronary os. These<br />

cannulae are used when the aortic root is opened for a valve replacement.<br />

Since the development of the retrograde cannula these cannulae are not often<br />

used. Retrograde delivery is easier and may be done while the surgeon continues<br />

to work.<br />

Vents<br />

The LV vents, PA vents and aortic root vents are the last of the cannulae<br />

types to be discussed. These vents are available in many sizes and shapes.<br />

The type of vent depends on the cannulation site. There are short metal tipped<br />

needles that fit in the aortic root. There are long thin cannulae placed through<br />

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Chapter 22 <strong>Cannulae</strong><br />

the right superior pulmonary vein, through the mitral valve and into the left<br />

ventricle. There are short right angled cannulae that may be placed into the<br />

apex of the left ventricle. There are cannulae placed in the main pulmonary<br />

artery distal to the pulmonary valve. The selection of these cannulae depends<br />

on the vent placement the surgeon prefers and the type cannula he prefers.<br />

NOTE: Always use a one-way valve in pump tubing connected to a<br />

vent to prevent accidental introduction of air into either the aorta or the left<br />

ventricle.<br />

The following is a chart of arterial cannulae, their pressure drops and<br />

maximum flows. These values <strong>com</strong>e from flow charts provided with the products.<br />

The venous cannulae chart is one that lists the standard re<strong>com</strong>mendations at<br />

certain weights. The charts are general re<strong>com</strong>mendations and more specific<br />

information can be obtained from the manufacturers.<br />

NOTE: On the arterial charts many cannulae reached the maximum<br />

flow on the chart before reaching the 100mmHg pressure drop. In these<br />

cases the maximum flow listed is actually less than its maximum flow that<br />

could be achieved at the 100mmHg pressure drop.<br />

ARTERIAL CANNULAE<br />

model size(OD) flow ( L/min ) pressure drop<br />

mmHg<br />

Bard<br />

Opti-Clear Aortic Arch 18 FR 4.75 100<br />

Opti-Clear Aortic Arch 20 FR 6.25 100<br />

Opti-Clear Aortic Arch 22 FR 7 70<br />

Opti-Clear Aortic Arch 24 FR 7 50<br />

Bio Medicus - Femoral<br />

96530-015 15 FR 3 100<br />

96530-017 17 FR 4 100<br />

96530-019 19 FR 5.5 100<br />

96530-021 21 FR 6.5 100<br />

DLP - curved tip arterial<br />

model 83020 20 FR 6.5 100<br />

model 83022 22 FR 8 81<br />

model 83024 24 FR 9 68<br />

DLP - descending arch cannula<br />

71321 21 FR 5 100<br />

71324 24 FR 6 100<br />

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Chapter 22 The Manual of Clinical <strong>Perfusion</strong><br />

ARTERIAL CANNULAE<br />

model size(OD) flow ( L/min ) pressure drop<br />

mmHg<br />

Gish-Curved tip, wire reinforced, with vent plug<br />

RA-1116 18FR 5.2 100<br />

RA-1117 21FR 6 56<br />

RA-1118 24FR 6 31<br />

Gish-Straight tip with vented connector<br />

NA-2116 18FR 5.2 100<br />

NA-2117 21FR 6 56<br />

NA-2118 24FR 6 31<br />

Research Medical<br />

ARL-2011-90-TA 20 FR 5.9 100<br />

ARL-2211-90-TA 22 FR 6 60<br />

ARL-2411-90-TA 24 FR 6 35<br />

Research Medical - Femoral arterial cannulae<br />

TF-A-020-25 20FR 3.3 100<br />

TF-A-022-25 22FR 5.25 100<br />

TF-A-024-25 24FR 6.2 100<br />

TF-A-024-25-H 24FR 7 87<br />

Sarns<br />

High Flow Aortic Arch 3.8 mm 1.5 100<br />

High Flow Aortic Arch 5.2 mm 3.5 100<br />

High Flow Aortic Arch 6.5 mm 5.25 100<br />

High Flow Aortic Arch 8.0 mm 8 60<br />

Sorin<br />

A211-30 3.0 mm 1.2 100<br />

A211-38 3.8 mm 1.8 100<br />

A211-45 4.5 mm 2.9 100<br />

A211-52 5.2 mm 4.1 100<br />

A211-65 6.5 mm 6.3 90<br />

A211-80 8.0 mm 6.5 40<br />

A211-95 9.5 mm 6.5 20<br />

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Chapter 22 <strong>Cannulae</strong><br />

model size(OD) flow ( L/min ) pressure drop<br />

mmHg<br />

William Harvey - Bard Arterial<br />

Type 1858 18 FR 4 100<br />

Type 1858 20 FR 5.5 100<br />

Type 1858 22 FR 6 85<br />

Type 1858 24 FR 6 70<br />

William Harvey - Bard Arterial<br />

Type 1860 18 FR 4 100<br />

Type 1860 20 FR 5 100<br />

Type 1860 22 FR 6 85<br />

Type 1860 24 FR 6 50<br />

VENOUS CANNULAE<br />

weight in kgs SVC/IVC <strong>Cannulae</strong> RA Cannula<br />

in French size in French size<br />

0-3 12 / 12 18<br />

3-6 12 / 14 18<br />

6-8 14 / 14 20<br />

8-10 14 / 16 22<br />

10-12 16 / 16 24<br />

12-15 16 / 20 24<br />

15-20 20 / 20 26<br />

20-25 20 / 24 28<br />

25-30 24 / 24 28<br />

30-35 26 / 26 30<br />

35-40 28 / 28 32<br />

40-50 30 / 30 36<br />

50-60 30 / 32 36<br />

60-70 32 / 32 51<br />

70-80 34 / 34 51<br />

80-90 34 / 36 51<br />

90-100 36 / 36 51<br />

100-110 36 / 38 51<br />

110-120 38 / 38 51<br />

120-130 38 / 40 51<br />

130-140 40 / 40 51<br />

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Chapter 22 The Manual of Clinical <strong>Perfusion</strong><br />

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