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Background: Neurologic Injury In Open Heart Surgery • Prevention: • Using systemic hypothermia (SH) during cardiopulmonary bypass (CPB) • causes a reduction in oxygen consumption and results in an increased neuroprotective effect. • SH does <strong>com</strong>e with other risks 2
Effects of Hypothermia and Rewarming Hypothermia • Decrease metabolism and oxygen demand • Decreases chance for ischemic injury in tissues • Delays the coagulation cascade and causes decreasing platelet function. • Requires the patient to be rewarmed. Rewarming • Historical strategies heat the body back to 37°C while causing the brain to be effectively warmed to 38 or 39°C. • The brain rewarms faster than other tissues of the body. • Increased temperatures can contribute to neurologic injury.
Page 1: Thromboelastographic Assessment of
Page 5 and 6: Balancing the Pros and Cons Hypothe
Page 7 and 8: Q: How much must the patient be rew
Page 9 and 10: Background: Thromboelastography (TE
Page 11 and 12: Hypotheses • H 0 : It is feasible
Page 13 and 14: Verification of Proper Temperature
Page 15 and 16: Results R values Trial 33 Trial 34
Page 17 and 18: Results MA Values Trial 33 Trial 34
Page 19 and 20: Conclusion • As a pilot study, si
Page 21 and 22: Future Research • A study modeled
Page 23: Thank you for this opportunity! Que

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