IDEXX Laboratories, Inc. - PerkinElmer
IDEXX Laboratories, Inc. - PerkinElmer
IDEXX Laboratories, Inc. - PerkinElmer
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Conjugate and Components by CE<br />
Conclusions<br />
• We have limited or no selectivity in disulfide reduction. Most of the IgY S-S is broken by<br />
the reduction.<br />
• We are relying on hydrophobic, H-bond and ionic interactions to maintain IgY structural<br />
integrity.<br />
• Of the 7 ENZ containing IgY conjugate species in CE only four contain active light chain.<br />
• Free, unconjugated light chain is a significant fraction<br />
• Conjugated heavy-chain-only species are a significant fraction<br />
20 | © 2012 <strong>IDEXX</strong> <strong>Laboratories</strong>, <strong>Inc</strong>. All rights reserved.
Change language